For a happier, healthier life
“Dedicated to helping people live happier and healthier lives by realizing their genetic potential�
Metagenics’ power Paul Coussement, CEO Metagenics Europe
Metagenics Europe is a leader in the development, manufacturing and distribution of nutrients for healthcare professionals in the European market. Metagenics works together with doctors, pharmacists and professional healthcare providers to improve the lives of their patients. Our products form an important addition to the therapeutic arsenal to fight nutritional deficiencies, chronic diseases, disturbed immunity… and are recommended by healthcare professionals every day. This respectful relationship, based on quality and scientific foundations, is our basis.
This is where the power of Metagenics lies. All of our products are the result of many years of scientific research by renowned Doctors of Medicine and scientists worldwide. Thanks to their findings, we have dozens of patents, granted or pending – something no one in our branch can claim. In our European headquarters in Ostend, we develop, manufacture and pack nutrients under strictly controlled conditions. In house manufacturing allows maximum control over the complete manufacturing and dispatching process.
Our team of 130 motivated professionals works full of passion, is one of the few probiotics to be Our product Probactiol dedication and with eye for quality towards one common goal: granted a quality label by the European Scientific League for to offer new perspectives on a quality life; a nice reward for Probiotics*, which makes it easier for healthcare providers to our hard work every day. make a distinction between scientifically documented products and products without such a label. * www.probioleague.org ®
Micronutrition and science The key to a healthier life Every human being has the genetic potential to live healthily. Changing nutritional habits, food composition and lifestyle have an impact on this potential and are co-responsible for the growing number of chronic diseases in our society. It is the mission of Metagenics to help people realize their genetic health potential through science-based micronutrition. Product innovation and development are the driving force of Metagenics. Thanks to continuous investments in scientific research and new technologies, the product formulas are perfectly adapted to the biochemical processes of the body. Metagenics looks for the most absorbable ingredients, the synergistic effects with other nutrients and the cofactors, activators and inhibitors which play a role in this process.
Stefaan Vervarcke R&D Manager For MetaRelax速 to have an optimal effect, we chose magnesium glycerophosphate. Scientific research has shown that this is an easily absorbed form of magnesium salt, without any gastrointestinal inconveniences. Further, we added vitamin B6, B9, B12 and taurine, as they support the effect of magnesium. This way, these nutrients have an optimal therapeutic effect.
Part of a global group
Metagenics Europe is a dynamic company in full expansion with its own activities in Belgium, the Netherlands, Luxemburg and Italy. In the other European countries, Metagenics is operational through our distributors. Metagenics Inc., with its headquarters in California, has activities in more than thirty countries. The company is the market leader in the United States, Australia and NewZealand. Metagenics employs 980 people worldwide. In June 2010, Metagenics became part of the Alticor group.
Fundamental research Studying and investigating the mechanisms at the basis of functional disorders, is the main activity of a team of over thirty scientists and physicians who work at Metagenics’ own research center (MetaProteomics Nutrigenomics Research Center) in the United States.
Jeffrey bland President Personalized Lifestyle Medicine Institute Today, “functional disorders” account for three quarters of the doctors visits. If they are not effectively treated, they may become chronic. Ever more people are starting to have functional problems, such as disturbed immunity.
In Europe, Metagenics organizes both fundamental and applied clinical research together with several important universities and renowned scientists. Furthermore, the R&D department of Metagenics commits itself to always base its work on the most recent, internationally recognized studies, published in important scientific journals. This way, only science-based (evidence-based) products are offered, which ensure an optimal nutritional support.
Mieke Van Den Driessche Science Manager In close cooperation with the University of Ghent, we have managed to develop and launch the product MenoHop速 onto the market. This contains the phyto-estrogen hopein which helps to relieve menopausal complaints. A double-blind placebo-controlled study among 67 menopausal women has shown that the women who took Menohop速 during 12 weeks, experienced significantly fewer hot flushes.
European production center Key criterium Quality formulas
Metagenics Europe accommodates a research and development department, a laboratory and a production and distribution line in Ostend. Through this vertical integration, Metagenics keeps maximum control on the complete quality process. Metagenics carefully selects the suppliers and ingredients, all components are subjected to a profound quality control.
Metagenics chooses the best ingredients in the right doses. The finished products exclusively contain nutrients which are easily absorbed and very well tolerated by the body.
Stefan Daenekynt QA/QC Coordinator Every day, 6.500 product units are produced. The powders are blended following strictly determined procedures and afterwards manufactured into Strict norms HACCP and ISO
tablets and capsules. The packaging is important as well, because it protects the products and makes them easy to use. Several of our nutrients are packed in a blister pack and we are a pioneer in the use of serving sachets
Metagenics applies the newest production methods following the most recent HACCP norms, which guarantees the food safety and quality of the products. For the same reason, the company has chosen implementation of the ISO9002 system, which entails the obligation to continuously improve the procedures, products and services. All developments within the company are securely followed up through external audits and by the Federal Agency for Food Safety. Moreover, all health claims comply with the guidelines of the European Authority for Food Safety (EFSA).
for powders.
In close cooperation with healthcare providers Since 1983, Metagenics has been working together with doctors, pharmacists and other healthcare professionals. Micronutrition is an efficient addition to the medicinal arsenal of health professionals, on the one hand to treat diseases or disorders, on the other hand to make the treatment more successful or to suppress the side effects. That is because there is a link between numerous diseases and a nutritional imbalance. Adding specific nutrients to the treatment, in the right doses, provides great advantages for the patient, both preventively and therapeutically. Thanks to the right nutrients, every person is able to optimally use their genetic potential.
CHRONIC DISEASE
NUTRITIONAL IMBALANCE
Barbara Samain Product Manager For Probactiol速, we offer coolers in several sizes. That is because it is recommended to store Probactiol速 in the refrigerator, to guarantee the amount of live bacteria up to the expiry date. This way, the quality is assured when the product reaches the patient.
Sharing knowledge
The Metagenics Academy Metagenics wishes to share its recent scientific insights. Via the Metagenics academy, evening lectures, weekend seminars and webinars are organized, presided by specialists. A team of nutritional advisors personally brings the newest scientific insights to healthcare professionals. At regular intervals, thousands of healthcare professionals are reached through our journals Meta Insights and Meta Solutions.
Maurizio Salamone Scientific Product Specialist Via the “education� section of our E-learning platform at www.metagenics.eu, we offer several extra trainings, customized to healthcare professionals. The sessions are brought by external key opinion leaders, whose concise approach is focused on practice. An extra advantage is that they can be followed at any time of day.
The Metagenics product line consists of over 250 formulas. Below, you will find some of our top products:
A couple of products in the spotlight Probactiol®
MetaRelax®
Highly dosed probiotic
In case of stress – fatigue
SCIENCE-BASED
SCIENCE-BASED
• Leyer G.J. et al. Probiotic Effects on Cold and Influenza-Like Symptom Incidence and Duration
• Driessens F. et al. On formulas for daily oral
in Childeren. Pediatrics Jul 27, 2009; 124;e172 – e179.
magnesium supplementation and some of their side
• Ringel et al. Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis
effects. Magnesium Bull 1993;15:10-12.
Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders:
• Galan P. et al. Dietary magnesium intake in
a double-blind study. J Clin Gastroenterol. 2011 Jul;45(6):518-2.
a French adult population. Magnesium Res
• Ibrahim F. et al. Probiotics and immunosenescence: cheese as a carrier. FEMS Immunol Med
1997;10(4):321-8.
Microbiol. 2010 Jun 1;59(1):53-9. Epub. • Sergey R. Konstantinov et al. S. layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions. PNAS 105/49, 19474-19479 December 9, 2008.
Nutrimonium™ Basic Nutritional Support
Eskimo®-3
SCIENCE-BASED
Heart and brain function
• Fuentes et al. Metabolic role of glutamine and
SCIENCE-BASED
its importance in nutritional therapy. Nutr Hosp
• Haglund O. et al. Effects of a new fluid fish oil concentrate, ESKIMO®-3, on triglycerides, choles-
199;11(4):215-25.
terol, fibrinogen and blood pressure. J Intern Med. 1990 May;227(5):347-53.
• Dos Santos et al. Glutamine supplementation
• Engström K. et al. Effect of fish oils containing different amounts of EPA, DHA and antioxidants
decreases intestinal permeability and preserves gut
on plasma and brain fatty acids and brain nitricoxide synthase activity in rats. Ups J Med Sci.
mucosa integrity in an experimental mouse model.
2009;114(4):206-13.
JPEN 2010;34(4):408-13. • Roberfroid et al. Prebiotic effects: metabolic and health benefits. Br J Nutr2010;104:suppl2:S1-63.
Our line of omega-3 products, Eskimo®, carries the international label “Friend of the Sea”. This guarantees that the sustainability of fisheries and aquaculture are respected during production.
E.Vlietinckstraat 20, B-8400 Oostende This information is intended explicitly for readers who deal with health and nutrition on professional
+32 (0)59 80 58 24
grounds. It is not intended for laymen or consumers. Diagnosis and treatment of a disease should happen under the responsibility of a recognized health professional.
info@metagenics.eu - www.metagenics.eu
v.u. Paul Coussement - Ganzendries 63 - 3212 Pellenberg
Metagenics Belgium BVBA