In Vivo Efficacy As an end-to-end solution provider and concentrated CRO in cancer immunotherapy discovery and
development, Creative Biolabs offers our clients with a comprehensive suite of validated in vivo cancer efficacy studies to advance their pre-clinical development projects in a cost-effective and
timely manner. We are committed to helping you to choose the most appropriate animal models,
study designs, and screening assays matched to your potential immunotherapy candidates, including checkpoint inhibitors, co-stimulatory agonists, oncolytic viruses, therapeutic engineered immune cells, cytokines and antibodies.
Anti-tumor Studies n
Tumor volume and growth curve;
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Tumor recurrence and metastasis;
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Survival curve;
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Cytokine production;
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Evaluation of tumor infiltrating lymphocytes, macrophages, dendritic cells, etc.
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Hematology (CBC/Diff) analysis;
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Biomarker evaluation.
Various approaches n
Flow immune-cytometry,
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ELISPOT assay,
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Bioluminescence imaging and
Highlights n
xenograft models, n
immunofluorescence, n
Histopathological analysis or tissue sampling,
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Immunohistochemistry analysis,
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Wright-Giemsa staining of the peripheral
Covering almost all cancer types for Reproducible and accurate efficacy data,
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Regulatory experts’ guidance to ensure compliance.
blood.
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