Epitope Binning and Mapping
Our Epitope Binning Technologies We offer high-resolution conformational epitope mapping service for complex proteins and conformational epitopes with >95% success. Our Shotgun Mutagenesis technology can reliably map conformational epitopes at even single amino acid resolution.
Co-Crystallography
Conformational epitopes
High resolution
Complex proteins Energetic hot-spots
Speed
Peptide Scanning
Epitope Binning
H/D Exchange
Shotgun Mutagenesis Epitope Mapping
We also have extensive experience in highly complex epitopes such as: l
Highly conformational epitopes;
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Epitopes on GPCRs, multi-transmembrane proteins and viral structural proteins;
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Epitopes on multi-subunit proteins.
Our End-to-end Epitope Binning and Mapping Services We offer various types of epitope binning and mapping services to help our clients get the key epitope data of mechanism of action to progress lead candidates, and also protect antibodies via stronger patents. Assay setup according to the specific program
Mutagenesis of the target protein
Antibody screening with the designed mutation array
Deliver final report including graphical representation of the epitope data, identification of critical residues, and mapped epitope
Our Characteristic Platforms u
SPR for high-throughput epitope binning
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IBIS MX96&CFM platform
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BLI platform-based Octet system
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ProteOn platform
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Biacore system
Creative Biolabs Confidential
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