Antibody Humanization
Powerful & Optimal Platforms u
CDR grafting
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Resurfacing
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SDR grafting
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Superhumanization
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Phage display
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Transgenic animals
Human string content (HSC) optimization
General Process & Our Strong Capacity We have launched the GHA® Platform to germinalize humanized antibodies as well as
Hi-Affi™ Platform to develop human monoclonal antibodies from non-human primates.
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Antibody Sequencing
Humanized Antibody Design
Antibody Production
Quality Tests & Delivery
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RNA extraction
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RT-PCR
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Sequencing
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Identifying back mutations
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Selecting human germlines
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CDR grafting
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Gene synthesis & cloning
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Transient transfection
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QC analysis
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ELISA against antigen
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Specificity and affinity
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Biophysical properties
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Universal antibody humanization service or customized service for special needs.
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30 days guaranteed workdays, once clients’ VH and VK sequences received.
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High-quality humanized candidates for delivery and ensure their epitope specificity & binding affinity.
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If clients are satisfied with humanized antibody variants, we offer the stable cell line further optimized for high yield expression and validated for scale-up.
Creative Biolabs Confidential
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