Antibodies for Breast Cancer Research Increase Your Efficiency and Value with Consistent Performance Antibodies: detection, imaging, diagnostic, etc. info@creative-biolabs.com www.antibody-creativebiolabs.com
Antibodies for Breast Cancer Research High-quality & validated antibodies for all your needs Creative Biolabs offers high quality ready-to-use catalogue antibodies, as well as flexible and comprehensive customized services for the antibody production to facilitate the basic discovery of breast cancer. Empowered by extensive experience and senior teams, we are committed to offering cuttingedge antibodies with superior performance for a wide range of applications to best maximize the success of your projects at the forefront of technological innovation.
Trusted Antibody Quality
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Antibodies for Breast Cancer Research Breast Cancer Breast cancer is the principle cause of cancer-related mortality among women worldwide. It's highly heterogeneous and can be classified into 3 types - TNBC, HER2+ and Luminal (non-HER2+).
Types, frequency and associated mutant genes TNBC Triple-negative breast cancers are ER-PR-HER2- and show significant but not complete overlap with the basal-like subtype of breast cancer (which is defined by differentiation state and gene expression profile).
TNBC 10% HER2+ 20%
HER2+ breast cancers have luminal features and are characterized by ERBB2 gene amplification and overexpression, leading to a dependency on HER2 signaling.
Luminal, non-HER2+ 70%
Luminal (non-HER2+) tumors are typically estrogen receptor positive, displaying high ERα levels. These tumors are dependent on estrogen for growth and, therefore, respond to endocrine therapy.
A Quick Glance at Key Targets in Breast Cancer Kind reminder: If you are interested in any other targets, please visit our website or contact us.
Commonly mutated targets
Key markers • • • •
ESR1 HER2/ERBB2 Ki67 Progesteron receptor (PGR)
• • • • • •
TP53 PIK3CA GATA3 MAP3K1 MLL3 CDH1
• • • • • •
USH2A PTEN RUNX1 NCOR1 RB1 TBX3
• • • • • •
PIK3R1 CTCF NF1 SF3B1 AKT1 CBFB
• •
FOXA1 CDKN1B
Key signaling factors • • • • • •
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SRC RAS BRAF MEK1 MEK2 ERK1/MAPK3
• • • • • •
ERK2/MAPK1 MAP2K4 JNK/MAPK8 STMN2 PIK3R1 PIK3R3
• • • • • •
AKT2 PTEN MDM2 p53 TBX3 GSK3B
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• • • • • •
Cyclin D1/CCND1 Cyclin D3/CCND3 CDK4 PRB1/2 NCOA3 MYC
• • • • • •
MYB FOXA1 GATA3 CBFB RUNX1 NCOR1
• •
TBL1XR1 p16Ink4A /CDKN2A
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Antibodies for Breast Cancer Research Antibodies for commonly mutated targets Targets TP53 PIK3CA GATA3 MAP3K1 MLL3 CDH1 USH2A
PTEN
RUNX1 NCOR1
RB1
TBX3
PIK3R1
CTCF
NF1
Clone
Applications
Species reactivity
Cat.No.
1285C CBWJW-083 1F7 CBYC-P379 H.843.0 4F3 1A12-1D9 7B5 CBLG1-676 CBFYM-0114 9D8 3A10 CBFYM-1193 1686CT202.60.69 CBYY-C0043 3G44 3G42
WB, IHC, IF, P, FC WB, P, PE IP, M, WB WB, IP, IC, IF P, IP, WB WB, E, F, IC, IF IC, IF, P, IP, WB E, IH, P, WB IC/IF, P, IP, WB F, IF, P, WB WB E, F, IC, IF, WB WB, E WB IS, WB, IF, IH, IP F, IF, IH, IP, WB E, F, IF, IH, IP, WB
Human, Mouse Human, Mouse, Rat Human Human Cattle, Human,Mouse, Rat Human Human, Mouse, Rat Human Human Human Human Human, Mouse Human Human Human, Dog, Mouse, Rat Human, Mouse Human
CBMAB-1838CQ CBMAB-T0002-WJ CBMAB-0266-LY CBMAB-P1796-YC CBMAB-P1797-YC CBMAB-P1795-YC CBMAB-G2217-LY CBMAB-G2223-LY CBMAB-G2244-LY CBMAB-M0132-FY CBMAB-1022-YC CBMAB-1021-YC CBMAB-M1350-FY CBMAB-K1430-LY CBMAB-C0119-YY CBMAB-C6150-LY CBMAB-C6148-LY
CBXU-038
WB
Human
CBMAB-U0154-CQ
10BA33
IF, WB
CBMAB-1516CQ
D4.3
WB, IP
1B8 CBYC-A1038 15B RXDMC 7A7A9 CBWJN-0129 9BA9 Rb1 (1F8) CBXC-2448
E, F, IC, IF, WB F E, IC, P, WB F E, IH, P, WB E, IH, WB E, WB IH, IF WB, P, C
CBXC-2426
WB, IF
CBYJT-2161 CBYJT-2160 CBYJT-2158
WB, IP, IF, E WB, IP, F WB, E, P, F, IC, IF
U5
C, IP, WB
2E7 8C11 2B12E2 1D11 CBXC-1870 2D1 A-12
E, M E, WB, P, IF, IC, F E, WB, IF E, WB WB, IH, P E, WB WB, IP, IF, P, E
CBWJN-0652
WB, E, IP, P
Human Human, Mouse, Rat, Hamster, Monkey, Dog, Chicken Human, Mouse Human, Monkey Human Human, Mouse Human Human Human Human Human, Mouse Human, Mouse, Rat, Dog, Primate, Rabbit Human,Rat, Mouse Human,Rat, Mouse Human Cattle, Human,Mouse, NonHuman primate, Rat Human Human, Mouse Human, Mouse Human, Monkey Human Human mouse, rat, Human Human, Mouse, Rat, Guinea Porcine
CBMAB-P3310-YC CBMAB-P3306-YC CBMAB-A4717-YC CBMAB-A4712-YC CBMAB-R3861-CN CBMAB-N1470-WJ CBMAB-N1469-WJ CBMAB-1448CQ CBMAB-C1002-CQ CBMAB-C0046-CQ CBMAB-C0034-CQ
CBMAB-T1266-YJ CBMAB-T1265-YJ CBMAB-T1263-YJ CBMAB-P1817-YC CBMAB-0832-CN CBMAB-P1814-YC CBMAB-C4674-LY CBMAB-C3807-LY CBMAB-C5096-CQ CBMAB-N2125-W CBMAB-N2129-WJ CBMAB-N0290-WJ
To be continued.
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Antibodies for Breast Cancer Research Antibodies for commonly mutated targets Targets SF3B1
AKT1 CBFB FOXA1
CDKN1B
Clone
Applications
CBXS-5436
WB
CBXS-2265 CBXS-1300 4E10 4C3 5C10 A-4 8C84 1E6 3C1 2D7 CBXF-3132 SX53G8 0.N.491 CBLC-LY-008
WB, IP, IF, E WB, P, IF WB, IH, IF, F E, IP, PLA, RNAi E, WB WB, IP, IF, E DB, C, WB IP, WB, M WB, E, P, IF E, WB, IH IC, IH, WB P F, IF, IH, IP, WB F, IF, C, P, IP, WB
Species reactivity Human, Mouse, Rat, Monkey, Hamster, Cattle Mouse, Rat, Human Human Human,Dog, Rat, Monkey, Mouse Human Human,Mouse, Rat, Dog Human Human Human Human Human Human, Mouse Human,Mouse, Rat, Primate Dog, Human,Mouse, Rat Mouse
Cat.No. CBMAB-S2647-CQ CBMAB-S5027-CQ CBMAB-S4159-CQ CBMAB-A2050-YC CBMAB-A2048-YC CBMAB-A2053-YC CBMAB-P0143-YC CBMAB-C9108-LY CBMAB-0194-YC CBMAB-F0941-CQ CBMAB-F2967-CQ CBMAB-F3828-CQ CBMAB-P0194-YC CBMAB-P0188-YC CBMAB-C9407-LY
Popular antibodies for key markers
Creative Biolabs' antibodies help meet your breast cancer research needs and budget requirements, increasing efficiency and offering the best value for a wide range of applications and specific assays.
ESR1 The anti-ESR1 antibody shows obvious nuclear positivity in human breast tissue using IHC. By western blot analysis, ESR1 is clearly detected around 68KDa. Targets
Clone
Applications
Species reactivity
Cat.No.
ESR1
ESR1/420 2G112B3 CBFYE-1267
WB, F, IF E, WB IC, IH, IP, WB
Human Human Hamster, Human, Mouse, Rat
CBMAB-E0318-FY CBMAB-1204-YC CBMAB-E1850-FY
Applications
Species reactivity
Cat.No.
F, E, IH, MC
Human
CBMAB-E1659-FY
P, WB F, IF, C, P, IP, WB
Human, Mouse, Rat, Monkey Human
CBMAB-E1645-FY CBMAB-E1648-FY
HER2/ERBB2 The anti-HER2 antibody shows distinct membranous positivity in HER2-negative and positive ductal carcinoma. Targets
Clone
HER2/ ERBB2
4D5-8 (TrasTuzumab) SPM495 9G6
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Antibodies for Breast Cancer Research Ki67 The anti-Ki67 antibody shows obvious nuclear positivity in human lymph node via IHC. By ICCIF, Ki67 is detected in nucleoli of human cell line U-2OS. Targets
Clone
Applications
Species reactivity
Cat.No.
Ki67
3D11 4A1 SP6
IH, P, WB IA, IH IH, IC/IF, P, C
Human Human Human, Mouse, Rat, Dog
CBMAB-K2136-LY CBMAB-K2137-LY CBMAB-K2173-LY
Progesteron receptor (PGR) By immunofluorescence and immunohistochemistry, PGR is detected in MCF-7 cell and formalin-fixed paraffin-embedded human breast cancer tissue. Targets
Clone
Applications
Species reactivity
Cat.No.
PGR
4E9 0.N.529 8A11H1
E, IF, P, WB IF, IH, IP, WB WB
Human Equine, Human,Pig, Sheep Human
CBMAB-P1613-YC CBMAB-P1605-YC CBMAB-P1614-YC
Popular antibodies for key signaling factors
Key signaling pathways involved in breast cancer include RAS/RAF, RAS/MAPK, PI3K/AKT etc. Creative Biolabs provides a wide range of antibodies for involved signaling factors, but not limited to these. Please contact us for more products information.
Targets SRC
RAS BRAF
MEK1
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Clone
Applications
CBXS-3318
F, IC, IH, IP, WB
CBXS-2306 CBXS-1773 Y13-259 1C8 CBFYH-1953 15B239 CBYY-2086 CBYY-1674 25/MEK1 CBFYM-1441
IC, IP, WB IH WB WB WB, IH, IF WB IH, P, WB F, IC, IH, P, WB F WB, P, IF, IP
CBFYM-1438
WB
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Species reactivity Cattle, Hamster, Human, Monkey, Mouse, Rat Chicken Human Mouse, Rat, Human Human, Monkey Human, Dog, Rat, Monkey, Mouse Human, Mouse Human, Dog Human Human, Chicken, Dog, Mouse, Rat Human, Mouse, Rat, Zebrafish Dog, Human, Mouse, Non-human primate, Rat
Cat.No. CBMAB-S6057-CQ
CBMAB-S5068-CQ CBMAB-S4590-CQ CBMAB-G6077-LY CBMAB-G6073-LY CBMAB-H2964-FY CBMAB-R0430-CN CBMAB-2435-YY CBMAB-2023-YY CBMAB-M0108-FY CBMAB-M1601-FY CBMAB-M1598-FY
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Antibodies for Breast Cancer Research Antibodies for key signaling factors in breast cancer Targets MEK2 ERK1/MAP K3 ERK2/MAP K1
MAP2K4
JNK/MAPK 8
STMN2
PIK3R1 PIK3R3 AKT2
PTEN
MDM2
p53 TBX3 GSK3B
Clone
Applications
Species reactivity
Cat.No.
CBFYM-1465
WB, E, F, IF
CBMAB-M1625-FY
CBFYM-1456
F
CBFYM-1455 3C9 1E5 12D11 4F3-A10-E7 CBFYM-1574 4C11 CBXS-4988 CBXS-5919
F, IC, IF, WB E, IC, IF, P, IP, WB E, P, F, IC, IF, WB WB, CI, IH, IF, P WB E, WB, IH, IC E, IC, IF, IH, C, P, WB F, IF, IH, P, IP, WB F, IF, IH, P, WB
CBFYM-1486
WB, IP
Mouse, Rat, Human Human, Chicken, Dog, Frog, Mouse, Rat Human Human Human, Mouse, Rat, Monkey Human, Mouse, Primate Human,Mouse, Rat Human, Mouse, Rat, Sheep Human, Mouse, Monkey Human Human, Dog Human, Mouse, Rat, Monkey, Dog
41/JNK/SAPK (pT183/pY185)
WB
Human, Mouse, Rat
CBMAB-0199-WJ
H.715.7
IP, WB
2F3 CBXS-3507 CBXS-1399 CBXS-0804 8C11 2E7
WB, IP, E, P E, WB WB, IP SE, E, WB E, WB, P, IF, IC, F E, M
U13
WB, IP
2F8 CBYC-P386 5B5 AW114 D16-H 10BA33
E, PLA, WB WB, P, IC, IF WB, IP WB, IP E, WB, IF, IC, IP IF, WB
D4.3
WB, IP
1B8 CBFYM-1965 CBFYM-1964 CBFYM-1961 7A4 CBWJW-083 CBLG1-2390 CBYJT-2161 CBYJT-2159 CBYJT-2160 E.948.2 3A11 3D6B4
E, F, IC, IF, WB E, F, IC, IF, WB E, WB, IH IC, IF, IH, IP, WB IF, IH, IP, WB WB, P, PE IF, SE, E, WB WB, IP, IF, E E, IC, WB WB, IP, F P, IP, WB E, WB WB, F, E, IH, MC
Hamster, Human, Mink, Mouse, Primate, Rat Human Human Mouse, Rat, Human Human Human, Mouse Human Mouse, Rat, Cattle, Human, Monkey Human Mouse, Rat, Human Human,Mouse, Rat, Monkey Human, Rat Human,Mouse, Rat Human Human, Mouse, Rat, Hamster, Monkey, Dog, Chicken Human, Mouse Mouse Human, Mouse, Rat Human Common fruit fly Human, Mouse, Rat Human Human,Rat, Mouse Human Human,Rat, Mouse Human, Mouse, Primate, Rat Human, Mouse, Rat Human, Mouse
CBMAB-M1616-FY CBMAB-M1615-FY CBMAB-1195-YC CBMAB-1192-YC CBMAB-E2167-FY CBMAB-P0477-YC CBMAB-M1740-FY CBMAB-1201-YC CBMAB-S2210-CQ CBMAB-S0768-CQ CBMAB-M1646-FY
CBMAB-0363-WJ
CBMAB-0148-WJ CBMAB-S6236-CQ CBMAB-S4257-CQ CBMAB-S3731-CQ CBMAB-P1814-YC CBMAB-0832-CN CBMAB-P1816-YC CBMAB-P1824-YC CBMAB-P1825-YC CBMAB-A2093-YC CBMAB-A2101-YC CBMAB-A2102-YC CBMAB-1516CQ CBMAB-P3310-YC CBMAB-P3306-YC CBMAB-M2140-FY CBMAB-M2139-FY CBMAB-M2136-FY CBMAB-0433-LY CBMAB-T0002-WJ CBMAB-G6398-LY CBMAB-T1266-YJ CBMAB-T1264-YJ CBMAB-T1265-YJ CBMAB-G5224-LY CBMAB-G0845-LY CBMAB-H1379-FY
To be continued.
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Antibodies for Breast Cancer Research Antibodies for key signaling factors in breast cancer Targets
Clone
Applications
Species reactivity
Cat.No.
Cyclin D1/CCND 1
CD1.1 SP4
WB, F, E, IH, IP, P, C WB, IH, IF, P
Human, Rat Human, Mouse, Rat, Baboon
CBMAB-C4698-CQ CBMAB-C4697-CQ
CBXC-1590
E, F, IH, IP, WB
Human, Rat
CBMAB-C4700-CQ
Cyclin D3/CCND 3
CBYY-C0337 CBFYC-1042
WB, IH F, IF, IH, IP, N, WB
Human Human, Mouse, Rat
CBMAB-C1127-YY CBMAB-C1099-FY
CBFYC-1040
WB, IF, IH, IP
Mouse, Dog, Human, Rat
CBMAB-C1097-FY
CDK4
5J210 3F9-B12-C8 0.N.199
IF, IH, IP, WB WB, E IF, IP, WB
Human, Mouse, Rat Mouse, Rat, Dog, Human, Pig Human, Mouse, Pig, Rat
CBMAB-C7749-LY CBMAB-C6085-LY CBMAB-C1404-LY
PRB1/2
BA0343
WB, P
Human
CBMAB-0690CQ
NCOA3
AX15.3 AC3 F-2
Human Human mouse, rat, Human
CBMAB-S2958-CQ CBMAB-N0184-WJ CBMAB-N1451-WJ
Human, Mouse, Chicken, Yeast
CBMAB-C9324-LY
3G32 CT14.G4 10A3 D-12 4-E3 4F6 CBFYH-0203 SP88 1A12-1D9 7B5 CBLG1-676 A-4 4D9 CBYY-C1023 CBYC-A1038 15B RXDMC 7A7A9 CBWJN-0129 9BA9
E, IH, P, IP, WB, CI WB, IH, IF, P WB, IP, IF, E WB, CI, F, E, IH, IP, P, C, MC E, IF, IH, IP, WB F, IF IP, WB WB, IP, IF, E WB, IP E, IF, P, WB WB, IP, IF, P, E F, P IC, IF, P, IP, WB E, IH, P, WB IC/IF, P, IP, WB WB, IP, IF, E IP, WB, M DB, IC, WB F E, IC, P, WB F E, IH, P, WB E, IH, WB E, WB
CBMAB-C6137-LY CBMAB-C0609-CQ CBMAB-V0114-LY CBMAB-A4588-YC CBMAB-A4587-YC CBMAB-F2445-CQ CBMAB-H1077-FY CBMAB-F0220-CQ CBMAB-G2217-LY CBMAB-G2223-LY CBMAB-G2244-LY CBMAB-P0143-YC CBMAB-0199-YC CBMAB-C2460-YY CBMAB-A4717-YC CBMAB-A4712-YC CBMAB-R3861-CN CBMAB-N1470-WJ CBMAB-N1469-WJ CBMAB-1448CQ
CBYJT-2103
E, WB, IH, IC
CBYJT-2102 CBYJT-2105 5-C3-1 2D9A12 1E12E10
WB, E, P, IC WB, IP, CI IF, IH, IP, WB WB, P WB, P
Human, Mouse Human, Primate Human, Mouse, Zebrafish Mouse, Rat, Human Human, Mouse, Xenopus Human Mouse, Rat, Human Human Human, Mouse, Rat Human Human Human Human Human Human, Monkey Human Human, Mouse Human Human Human Human,Mouse, Rat, Cattle, Pig, Dog, Zebrafish Human,Mouse Human, Monkey Mouse Human Human, Mouse, Rat
9E11
MYC
MYB
FOXA1
GATA3
CBFB
RUNX1
NCOR1
TBL1XR1
p16Ink4A /CDKN2A
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CBMAB-T1202-YJ CBMAB-T1201-YJ CBMAB-T1204-YJ CBMAB-C7387-LY CBMAB-C4943-LY CBMAB-C3919-LY
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Antibodies for Breast Cancer Research “ Creative Biolabs offers comprehensive antibody products and related services. Please contact us for more detailed information and our team will get back to you as soon as possible. We are always here to serve you to help promote your projects. The list above only exhibits a small part of our products. Please visit our website for more information. https://www.antibody-creativebiolabs.com
Antibody Services Guidance What's my target?
Popular
Specific
Catalogue Ab Available or not in Creative Biolabs?
Custom Ab
No
Specific epitope
Yes Order the Catalogue Ab Online
Mouse or rabbit? Batch to batch reproducibility Monoclonal Ab
Test the Ab
Polyclonal Ab
Epitope synthesises or not?
Suit my project
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Antibodies for Breast Cancer Research Highlight Features: Innovative technologies and ideas Numerous worldwide customers High-level Ph.D. scientists and experienced technicians
High efficiency and short turnaround time Close collaboration Extensive forefront knowledge sharing Advanced and one-stop platforms
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With extensive experience and over a decade superior antibody services for numerous worldwide customers, Creative Biolabs has blossomed into a service leader in the field of antibody products and services. We offer a comprehensive set of package services and also individual modules, and aim to maximize the success of your breast cancer research discovery and development.
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Custom Antibody Service Process
Submit protein sequence
Antigen design
Antigen synthesis
Antibody production and purification
Quality control
Delivery
A wide range of applications WB
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IHC
ELISA
IP/ChIP
IF/FC
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Functional assay
Expedite Your Breast Cancer Research Leverage the expertise of our senior scientists to obtain a wide array of antibodies or custom products to fit your project.
Tel: 1-631-381-2994 Fax: 1-631-207-8356 Email: info@creative-biolabs.com
www.antibody-creativebiolabs.com 45-1 Ramsey Road, Shirley, NY 11967, USA
The trusted antibody and custom service & solution provider.
Our promise: Guaranteed product quality, expert customer support.
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