CDA Journal - November 2021: The 20th Anniversary of Dental Stem Cells

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zirconia implants C D A J O U R N A L , V O L 4 9 , Nº 11

Pre-Sintering Airborne Particle Abrasion Improves Surface and Biological Properties of Zirconia Tanjira Kueakulkangwanphol, DDS; Nichamon Chaianant, DDS, PhD; Yanee Tantilertanant, DDS, PhD; and Weerachai Singhatanadgit, DDS, PhD

abstract Background: Surface topography of a zirconia dental implant has a major impact on osseointegration and clinical success. Modification of a fully sintered zirconia surface can be problematic due to its high strength and bio-inert surface. Methods: The present study therefore aimed to investigate the effect of airborne-particle abrasion of presintered zirconia on surface properties and biological performance of the resulting fully sintered zirconia. Results: The results showed that surface topographies of fully sintered zirconia were influenced by abrasive particle size and blasting time used in repeated pre-sintering airborne particle abrasion. Well-optimized pre-sintering airborne-particle abrasion of zirconia surface could render a highly roughened and hydrophilic surface with increased fibronectin-to-albumin adsorption ratio and mesenchymal stem cell adhesion. Practical implications: This technique may be suitable for modifying zirconia surface to facilitate osseointegration of zirconia-based dental implants. Keyword: Pre-sintering airborne-particle abrasion, zirconia, surface roughness, surface hydrophilic, mesenchymal stem cells

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