cohen_oct202011

Influencing Behavior of Providers and Pa4ents: The Micro-­‐Financial Environment Jessica L. Cohen Harvard School of Public Health & Brookings Ins4tu4on October 20, 2011

The Pa4ent:

Incen4ves to Use RDTs Ø An RDT is a “consump4on good”: consume informa4on about true cause of illness

Ø “Value of informa4on” = willingness to pay for info, prior to decision

Ø Value = Benefit – Cost

Ø Direct and indirect costs of purchasing informa4on.

Ø No direct benefits to RDTs per se—benefit is the aversion of costs – One benefit is poten4ally avoiding cost of unnecessary an4malarial.

– Another is avoiding an illness that progresses in severity

Ø Pa4ents who want informa4on on true cause of illness have op/ons, of which RDTs are only one, each with an associated cost and benefit – Presump4ve treatment of malaria is one way of purchasing info – “Wait and see” is a form of informa4on acquisi4on too

Condi4ons for Pa4ents to Want RDTs I. There is Some Value to the Informa4on Ø RDTs only valuable in condi4ons of uncertainty

Ø Value of informa4on is low when:

1) People are sure they know when symptoms equal malaria or symptoms do

not equal malaria.

2) People don’t believe test is accurate. Or at least more accurate than subjec4ve assessment of probe(malaria|symptoms).

Ø The RDT most valuable (i.e. WTP highest) when least certain in own assessment and most certain about accuracy of test.

Condi4ons for Pa4ents to Want RDTs II. Benefit of the Informa4on Exceeds its Cost Cost:

Ø Price of the RDT Ø Opportunity cost of 4me Ø Non-­‐economic (e.g. psychological, sociological)—fear, reluctance to try new technology, etc.

Benefit:

Benefit is in aversion of costs incurred if don’t take RDT. Directly linked to what alterna/ves people have.

E.g., if relevant alterna4ve is presump4ve treatment, poten4al benefits are:

Ø Avoiding the cost of the an4malarial Ø Avoiding mis-­‐diagnosis (poten4ally lead to worse illness) Ø Non-­‐economic (e.g. psychological)—uncertainty avoidance

Condi4ons for Pa4ents to Want RDTs II. Benefit of the Informa4on Exceeds its Cost Costs are lowered when:

Ø RDTs subsidized and/or measures taken to reduce mark-­‐ups Ø RDTs are easily accessible & available (OTC, provided by CHWs, etc.) Ø They become familiar, there is learning-­‐by-­‐doing or learning from peers

Benefits are increased when:

Ø An4malarials are expensive (or have side effects) Ø Public facili4es are far, inconvenient, not well-­‐stocked, etc. Ø Probability it is not malaria is high & consequences of delay in trea4ng not-­‐malarial illness is high (e.g. for pneumonia in children) Ø Alterna4ve types of learning unreliable—e.g. microscopy high error rate

Condi4ons for Pa4ents to Want RDTs

III. Net Benefit of RDTs Higher than Alterna4ves Op4on 1: Do Nothing/Wait

Costs: Zero today. Possibly high future costs if illness gets worse.

Benefits: Avoid the cost of medicine and opportunity cost of seeking care.

Op4on 2: Treat Presump4vely with OTC An4-­‐malarial

Costs: Direct cost of meds. Possibly high future costs if not malaria & gets worse.

Benefits: Avoid the cost of seeking care at facility & possibility of missed malaria.

Op4on 3: Buy an RDT at Drug Shop

Costs: Direct cost of RDT & of meds if test posi4ve. Possibly high future cost if RDT is nega4ve and true illness gets worse.

Benefits: Avoid the cost of seeking care at facility & possibility of missed malaria.

Op4on 4: Go to Health Facility

Costs: Direct costs of health facility visit (depends on context; usually an4malarials free). Direct & indirect costs of travel & wai4ng, stockouts.

Benefits: Possibly most accurate diagnosis (including assessment & treatment of alterna4ve illness)—avoid missed illness. Avoid costs of an4malarial.

Pa4ents: Evidence Cohen, Dupas & Schaner (2011); Western Kenya

• Pre-­‐AMFm, gave households cards allowing purchase of subsidized ACTs & RDTs in local drug shops • Random varia4on in price of ACTs & RDTs; RDTs varied from $0 -­‐ $0.20 • Measured WTP & impact on treatment seeking

Some basic results:

Ø Doubled rate at which illnesses diagnosed (from 22% to 44%) Ø Did not crowd out diagnosis (microscopy) at health center Ø Good distribu4onal effects : illiterate: 14%-­‐> 31%; literate: 27% -­‐> 52% Ø RDT seeking increasing with “predicted posi4vity” (Figure ) Ø 80% of the 4me, when people bought ACTs, bought RDT also. Willing to pay (at these low prices). Ø People no more likely to use RDT when ACT price was higher. Ø 99% of RDT-­‐posi4ve bought ACT; 60% of RDT-­‐nega4ve bought ACT

Pa4ents: Evidence Cohen (2011); Central Uganda

• Pre-­‐AMFm. Subsidized ACTs offered for sale with varying packaging/ messaging to encourage adherence • RDTs randomly offered to some pa4ents when arrived at shops to buy ACT • Measuring impact of packaging and RDT on adherence to ACTs • Measure beliefs about whether the illness was malaria prior to doing RDT

Some basic results: Ø Ø Ø Ø

There is significant uncertainty about the likelihood of malaria (Fig1) People are decent guessers (but not perfect) about chances (Fig2) Over-­‐treatment much more likely for adults (Fig 3) RDT-­‐posi4ve 25% more likely to adhere, but not necessarily the effect of RDTs

Cohen, Dupas, Schaner (on-­‐going); Western Kenya • Ask about chances the illness is malaria before and ater RDT. Ø People revise upward when test posi4ve (but not to 1), revise downward when test nega4ve (but not to 0); suggests some belief in test but not perfect

Providers:

Incen4ves to Sell RDTs; Components of RDT Prices Ø Commonly heard that shops wouldn’t want to sell RDTs. Why? – Well-­‐known that people “over-­‐treat” malaria – Shops could lose money on these unnecessary an4malarial purchases

Ø True, but they can make addi4onal profits from: – Selling the test – Selling alterna4ve treatment when test is nega4ve – Selling the an4malarial at a higher price (WTP could increase w/ certainty)

Ø As profits from these products increase, drug shops become more willing to sell RDTs

Ø Profit will depend on what they can charge, which in turn depends on the things highlighted on the part of consumers – E.g. price of RDT can be higher as belief in test increases

Ø Will depend on market condi4ons (compe44on) as well as things like value of reputa4on (avrac4ng repeat customers).

Providers: Evidence I. Cohen & Dickens (2011): Economic Model of Shop Behavior No externali4es to over-­‐treatment & Shops & customers have accurate beliefs about malaria probability Externali4es from over-­‐ or treatment

Sell RDTs under all condi4ons we would want them to (max welfare)

Consumer probability belief > than shop owner’s

or

Subsidies for an4malarials

Shop under-­‐provides RDTs

Mechanisms to increase RDT provision:

1. BCC targe4ng beliefs about malaria prevalence & accuracy of test 2. Increase compe44on between shops 3. Introduce RDT subsidy

Op4mal RDT Subsidy =

(Rate of overtreatment)*[(Subsidy for an4malarial) + (Social Cost of Over-­‐treatment)]

Providers: Evidence Cohen, Fink, Dickens (Uganda; Ongoing)

• Sell subsidized RDTs ($0.50) through wholesaler to shops in 8 districts.

• Implement BCC campaign (with Uganda Health Marke4ng Group) to test key messages on RDT use and adherence to test results

Some results so far:

Ø RDTs are converging in price to around $1 (100% mark-­‐up) Ø Rural shops more likely to sell/promote the RDTs than “urban” ones (stated reason: proximity of urban shops to health centers) Ø RDTs more oten purchased for children than adults Ø Shops are crea4ve in promo4ng the RDTs (for example…) Ø RDTs maintaining quality (based on lot tes4ng ater 4me in field) Ø Shops easily trained for the most part & following protocol Ø Some crea4ve shops are offering a “bundle price” for the RDT and treatment

Summing Up: Some Key Missing Pieces • Not really enough to know willingness to pay for RDTs. Why? Ø This is likely to change over 4me as people revise expecta4ons about the prob(malaria|symptoms) and the belief in the test. Ø Very high rates of over-­‐treatment & ignoring test results could be “short-­‐ run”

• What are the key behavioral messages to encourage diagnosis and adherence to test results? This could speed up acceptance of RDTs. • Cri4cal need for bever evidence on how treatment seeking varies with underlying endemicity – For example, oten assume RDTs more cost-­‐effec4ve in low endemicity se|ngs, but this is only if people are really bad at guessing.

• How do RDTs affect adherence to ACTs? – Important for cost-­‐effec4veness calcula4ons which are majorly determined by probability of resistance

• What determines shops’ RDT pricing decisions? Are there any policy levers we can pull to influence them?

• Are there technological improvements in RDTs that bever fit consumer/

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