The Most Influential Women Leaders In Real Estate

A PATH TO EXCELLENCE

TRACY UTTLEY

Real Estate Agent Realty Group

From Editor’ s Desk

- Virginia Rometty, CEO of IBM

Oneofthemostlucrativesectorsintheeconomyisrealestate,likeasharkinthesea.The marketsize,itsgrowthpattern,highreturns,andnottoforgetthepowerfulcontactsaresome ofthefewmainfactorsthathaveencouragedpeopletoenterthismarket.Allyouhavetodo tosurvivethismarketisgrabtherightopportunities.

CIOWomenMagazine’sthisissueofTheMostInfluentialWomenLeadersinRealEstate featuresthestoriesofwomenwhohavetakentherealestatemarketbystormandhaveleft theirimprints.

FortheCoverreadabout-

Astheleaderofaprominentrealestatefirm, hasachievedunprecedented TracyUttley successanddemonstratedoutstandingleadershipskills,earningthisrecognition..Her accomplishmentsandinnovativeapproachhavenotonlyimpactedthelocalrealestatemarket butalsoinspiredcountlessaspiringprofessionalstofollowinherfootsteps.

Uttley’sjourneyinrealestatehasbeenmarkedbyaseriesofremarkableachievements. Besidesquicklybecomingoneofthetopresidentialrealtorsinherarea,underherleadership, hercompany,UttleyRealEstatebrokeredbyRealtyGroup,hassuccessfullyundertaken severalhigher-profileprojects,includingthesaleofherfirstlargescalecommercial building..Withaninnateunderstandingofmarkettrendsandakeeneyeforbuyingand sellingopportunities,Uttleyhasconsistentlydeliveredexceptionalresultsforherclients.

WhatsetsUttleyapartisherabilitytoleadbyexampleandinspirethosearoundher.

KathyColvilleisadistinguishedrealtorandaleaderinherfield,inspiringwomentobreak barriersandshatterglassceilingsintherealestateindustry

KathyColvilleisasuccessfulrealtorwithover37yearsofexperienceintheindustry.Her journeyasarealestateagentbeganin1986,shortlyafterdecidingtosellhercondoandmove intoasingle-familyhomewithherfirsthusbandandtwosmallchildren.Kathydecidedto becomealicensedrealestateagenttostaycurrentwiththehousingmarket.

Aftercompletingtherequiredcoursesandpassingtheexam,KathyColvillejoinedTownand CountryRealEstatefirm,whereshequicklylearnedthatholdingopenhouseswasthebest waytoattractbuyers.Sheheldopenhousesforanyhomeinthefirst-timebuyer’spricerange andsoonhadherfirstclient,whichledtoherbecomingafull-timeprofessionalrealtor

“I learned to always take on things I d never done before. Growth and comfort do not coexist.”

This list is NOT a ranking. The companies on listed in magazine serve different aspects of the market, making ranking them in any order except revenue impossible and unfair. We try to bring a perfect platform for business organization to showcase their valued products/ services.

PR News Section

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~ AmantyahasbeendeclaredaleaderintheSmall andMediumServicesProvidersverticalinER&D Services–Telecommunicationssegmentandhas beenrankedintheExecutiveZoneintheoverall ER&DcategoryinZinnovZones’annualER&D Servicesratings.

AmantyaTechnologiesInc.,aleadingglobalproduct engineeringandsystemintegrationcompany, announcedtodaythatithasbeenrankedinthe ‘LeadershipZone’intheER&DServices–Telecommunicationsverticalandinthe‘Executive Zone’intheoverallER&DServicescategoryin ZinnovZones’2022GlobalER&DServicesRatings.

Theannualreportbytheprestigiousglobal managementconsultingandstrategyconsultingfirm providesa360-degreeevaluationofengineering researchanddevelopment(ER&D)service providers,identifyingtheirexpertiseandscalability acrosskeymarketsandtechnologies,andis consideredanindustrystandard.The2022study evaluatedover75+topglobalserviceproviders acrossindustryverticalsandmicro-verticalsfortheir digitalengineeringprowess.Theratingshavebeen assessedonmultipledimensions,including scalability,growthrate,innovationandIP,services capability,maturityofdeliveryandservices capabilities,ecosystemlinkages,andfeedbackfrom enterprisebuyers.

“Wearethrilledtoreceivethisrecognitionandbe includedinZinnovZones’ER&DServicesratings. It’sahugehonortobefelicitatedbysucha prestigiousbodyandberecognizedforourstrong capabilitiestodelivervalue-addedservicesand solutionsinthe5Gwirelessanddigitaldomains. BuildingacultureofR&Danddisruptingnew

technologiesareattheheartofwhatwedoat Amantya.Ourin-houseinnovations,5GSACore, 5GNetwork-in-a-Box,and5Genterprisesolution, 5GAstra,areatestamenttothiscommitment.

Theratingacknowledgesourcontinuedabilityand deepcommitmenttoexploringanddisrupting cutting-edgetechnologiesthatdrivenext-gen digitaltransformations.Overthepastfewyears,we havepartneredwithsomeofthebestcompanies globally,andourleadershippositioninginZinnov ER&DServicesreiteratesourgrowingstaturein themarket.Welookforwardtoacceleratingand broadeningourexpertiseinemergingtechnologies andbeingafrontrunnerinprovidingsolutionsthat transformeverydayexperiences,”saidAnuradha Gupta,CEO,AmantyaTechnologies,Inc.

Thecompanywasalsorecognizedas“BestSMEin TelecomEcosystem2022”atIndiaMobile Congressand“MostPreferredWorkplacein IT/ITES2022-23”byMarksmenDaily

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AboutAmantyaTechnologies,Inc.

AmantyaTechnologiesisaleadingproduct engineeringandsystemintegrationcompanywith operationsintheUSA,Canada,andIndia (Gurugram,Bangalore&Nagpur).Aglobal organizationwithprovenexpertiseinnextgenerationtechnologieslike5G,IoT,AIML,edge, andcloudservices,Amantyaworkswithsomeof theworld’sbestbrands,includingFortune500 companies.

Formoreinformation,pleasevisit amantyatech.com

C O N T TRACY UTTLEY

E N T S

The Many First Women

Meryl Streep - How Meryl Streep Became The Best Performing Artist Of Her Time?

Profile

Leading With Purpose

Monuments

Eiffel Tower - All You Need To Know Before Visiting Eiffel Tower In Paris

Article

Ai Tools Are Finally Changing The Biopharma Landscape

Heroes.Moreover,shebecamea memberoftheAcademyofMotion PictureArtsandSciences(AMPAS). Merylhasreceivedherhonorary degreefromPrincetonUniversityin Princeton,NewJersey.Fortheseand manyothermemorableperformances, shewasranked37thGreatestMovie StarofalltimebyEntertainment Weekly.

Thingsyouprobablydon'tknow aboutMerylStreep

DoyouknowMerylishernickname givenbyherfather?Beingadie-hard fanofMerylStreep,youmightknow manyinterestingfactsabouther.Inthis section,youwillexploresomelesserknownfactsabouther

Ÿ Merylhadappliedtotrademark hername

Justacelebritything,MerylStreephad appliedtotrademarkhername.She appliedtotheUnitedStatesTrademark Officetotrademarkhernameofficially Itgaveherexclusiverightstouseher nameintheentertainmentindustryof Hollywood.Thisapplicationreferred tohermovieappearances, engagements,television,etc.toprevent anyoneelsefromusinghernameand earningmoneyofftheirbrand.Itgave heranextraadvantagetoprotecther namefromanyunauthorized commercialuse.

Ÿ Sheholdsanadvanceddegree fromanIvyLeagueuniversity

Beingacheerleaderinhighschool, Meryldidn'tneglectherstudies.In 1969,shejoinedVassarCollegeafter completingherhighschoolstudiesand receivedaBachelor'sDegreeinFine Arts.Laterin1975,shecompletedher Master'sdegreeinthesamefieldfrom YaleUniversity.Furthermore,shewas awardedanHonoraryDoctorofArts degreebyDartmouthCollege.Meryl StreephashonorarydegreesfromIvy Leagueuniversities.

Ÿ MerylStreepwasonceevicted fromherapartment

MerylStreepwasinvolvedina relationshipwithJohnCazalewhowas apartof“TheGodfather”movie.She sharedanapartmentwithhimandtheir relationshiplastedforalmostthree years.Johnwasdetectedwithlung cancerandMerylhadtosettlehis medicalbillsafterhisdeath. Consequently,shewasevictedfrom theapartment.Eventually,Merylhad tostaywithherbrotherandhisfriend.

Ÿ Shegaveawayhersalarytothe Women'sHistoryMuseum

In2011,MerylStreepplayedtherole ofBritishPrimeMinisterMargaret Thatcher,thefirstfemaleprime ministeroftheUnitedKingdominthe movie“TheIronLady”.Surprisingly, shewaspaidonemilliondollarsforthe movieandtherolemadeherwinthe thirdOscar.Shedonatedherentire earningfromthemovietobuilda HistoryMuseumattheNationalMall inWashington.Themuseumwasbuilt toteachthehistoryofwomeninthe world.

Ÿ MerylStreephastakentraining foroperasinging

YoumightknowthatMerylStreephas beennominatedforGrammyAwards forherworkin“MammaMia”.She hasbeentrainedasanOperaSinger underherteacherEstelleLiebling. MerylStreepstarredinMusicalssuch as“IntotheWoods”,and“Mamma Mia:HereWeGoAgain!”

Ÿ Shewasnominatedfor21 AcademyAwards

MerylStreepwasnominatedforatotal of21AcademyAwardsandwonthree Oscarsforheroutstanding performancein“Kramervs.Kramer”, “Sophie'sChoice”,and“TheIron Lady”.Mostofthesenominationswere forBestActressandBestSupporting Actress.

Ÿ MerylStreepdonatedDevil WearsPradawardrobeforthe causeofcharity

MerylStreepplayedtheroleof MirandaPriestlyin“TheDevilWears Prada”.Itwasoneofthemostfamous rolessheplayedeverinhercareer Morethanonemilliondollarswere spentonhercostumedespitetheloans fromvariousdesigners.Themovie spenthugemoneyonthecostumeas itsmainfocuswasonhigh-end fashion. Ratherthankeepingthat wardrobe,Meryldonatedittoacharity auction.

Ÿ SheleftherfirstOscarAwardin theladiesroombymistake

MerylStreepwonthefirstOscar AwardforherroleinKramervs. KramerastheBestSupportingActress in1979.Aftergivingheracceptance speechonthestage,shewenttothe ladiesroomandmistakenlyleftthe award.Themomentwashilariousas shegottoknowaboutitonlywhen someoneshouted,“Someonehasleft theOscarAwardintheladiesroom.”

AwardSeriesofMerylStreep

MerylStreephasbeentheTop AchieverinvariousAward Nominationsandhaswonmanyof them.Sheistherecipientof3 PrimetimeEmmyAwardsalongwith nominationsfor17ScreenActors GuildAwardsand15BritishAcademy Awards.Merylhad31GoldenGlobe Nominations,however,shehad received8suchawards.Furthermore, in1979,sheperformedinthesmall televisionseriesknownasHolocaust, whichgrantedherEmmyAward.Later on,shegotnominatedforAcademy AwardforthefilmDeerHunter

VariousOscar-assignedrolesofMeryl Streepinclude,TheFrench Lieutenant'sWoman(1981),Silkwood (1983),OutofAfrica(1985),Ironweed (1987),EvilAngels(1988),Postcards fromtheEdge(1990),TheBridgesof

MadisonCounty(1995),Doubt(2008), OneTrueThing(1998),Musicofthe Heart(1999),Adaptation(2002),The DevilWearsPrada(2006),Intothe Woods(2014),andFlorenceFoster Jenkins(2016).

10Must-WatchMerylStreepFilms

MerylStreephasperformedinnumerous moviesandhasbeenacclaimedforher performancenotjustbyaudiencesbut alsobycritics.Since1975,shewas featuredin75moviesandappearedon someotherplatformsinmedia.Itisa difficultjobtochoosethebestMeryl Streepperformance.However,therearea fewMerylStreepfilmsyoucan'tmiss:

1.Sophie'sChoice(1982)

2.Doubt(2008)

3.TheHours(2002)

4.TheBridgesOfMadisonCounty (1995)

5.Adaptation(2002)

6.KramerVs.Kramer(1979)

7.LittleWomen(2019)

8.Manhattan(1979)

9.FantasticMr.Fox(2009)

10.TheDeerHunter(1979)

FAQs

1.HowoldisMeryl Streep?

Currently,in2023,Meryl Streepis73yearsold.

2.WhatisMerylStreep's networth?

AccordingtoCelebrity Networth,MerylStreep'snet worthis160milliondollars.

3.WhoisMerylStreep's husband?

MerylStreepmarriedDon Gummerin1978andthe couplehasfourchildren.

4.WhendidMerylStreep startacting?

Merylstartedactinginher earlycollegedays,however, shewasfeaturedfirsttimein 1977inthemovie“Julia”.

TRA

TRACY UTTLEY

CoverStory

Intheever-evolvingworldofreal estate,TracyUttleystandsoutasa trailblazerandasuperbleader With herunwaveringcommitmentto excellenceandremarkablevision,she hasmadeasignificantimpactinthe industry TheEnterpriseWorldisproud tointroduceherasoneoftheMost InfluentialWomenLeadersinReal Estate.

Astheleaderofaprominentrealestate firm,Uttleyhasachieved unprecedentedsuccessand demonstratedoutstandingleadership skills,earningthisrecognition..Her accomplishmentsandinnovative approachhavenotonlyimpactedthe localrealestatemarketbutalso inspiredcountlessaspiring professionalstofollowinher footsteps..

Uttley’sjourneyinrealestatehasbeen markedbyaseriesofremarkable achievements.Besidesquickly becomingoneofthetopresidential realtorsinherarea,underher

leadership,hercompany,UttleyReal EstatebrokeredbyRealtyGroup,has successfullyundertakenseveralhigherprofileprojects,includingthesaleofher firstlargescalecommercialbuilding.. Withaninnateunderstandingofmarket trendsandakeeneyeforbuyingand sellingopportunities,Uttleyhas consistentlydeliveredexceptional resultsforherclients..

WhatsetsUttleyapartisherabilityto leadbyexampleandinspirethose aroundher.Shebelievesinfosteringa cultureofcollaborationand empowerment,recognizingthatthe strengthofateamliesinitsdiversity andsharedgoals.

Hereffectivecommunicationskills, coupledwithherstrategicmindset, enablehertorallyherteamtoward achievingambitioustargets,whilealso ensuringthateveryonefeelsvaluedand supported.Uttleycontinuestoshapethe futureofrealestate,leavinganindelible markonthefieldandpavingtheway forfuturegenerationsofleaders.

To reinforce my newfound mindset, I wrote the affirmation ‘I am Unstoppable’ on my bulletin board. Initially, I found it amusing to read such a bold statement, but as I embraced my own audacity, I became increasingly daring.

ExceptionalRealEstateExperiences

LedbyUttley,UttleyRealEstatebrokeredbyRealty Groupisatrustedrealestateagencyknownfor deliveringexceptionalserviceandsatisfaction.With afocusonintegrityandprofessionalism,the companyguidesclientsthrougheverystepoftheir realestatejourney

Itspersonalizedapproach,marketexpertise,and commitmenttoclientrelationshipssetitapart.Uttley RealEstate’strackrecordofsuccessandpositive reviewssolidifyitspositionasapremieragency dedicatedtoprovidingexceptionalrealestate experiences.

In2020,TracyUttleyobtainedherrealestatelicense, markingapivotalmomentinhercareer Whileshe hadsuccessfullygeneratedsubstantialprofitsfor othersasaSalesandMarketingDirector,sherealized thatshehadnotplacedenoughvalueonherself. Recognizingthisrevelation,shefeltasurgeof determination,akintoaracehorseatthestartinggate, eagertosprintforward.Sheadds, “To reinforce my newfound mindset, I wrote the affirmation ‘I am Unstoppable’on my bulletin board. Initially, I found it amusing to read such a bold statement, but as I embraced my own audacity, I became increasingly daring.”

OnenotableexampleofUttley’sboldapproachwas herdoor-to-doorprospectingstrategy.Fearlessly,she knockedonpeople’sdoors,askingiftheywere interestedinsellingtheirhomes.Thisunconventional methodprovedfruitfulwhenshesecuredalisting valuedat$845,000—atestamenttoherfearless persistenceandwillingnesstostepoutofhercomfort zone.

LeadingtheWayinRealEstate

“Growing up in a family business, I understand the importance of exceptional service.”

Uttley’sparents,successfulentrepreneurs,owned55 businessesovertheyears.Shewitnessedherfather’s negotiationskills,inspiredbyhergrandmother’s dealingswithcowtradersontheirWisconsinfarm. Aftercollege,sheworkedasawaitressatHotelDel CoronadoinCalifornia,impressinghermanagerwith herMidwesternworkethic.

ShelaterreturnedtoMinnesota, joininghotelsalesandrisingto DirectorofSalesandMarketing.Her experienceinsalesandmarketing, coupledwithherownershipofhotels andrestaurants,providesherakeen understandingofthemarket.She excelsinhelpingclientsachievetop dollarfortheirhomes,leveragingher energy,communicationskills,anda lifetimeofbusinessexpertise. Drivenbyaninspiringrevelation, Uttleyembarkedonatransformative journeyafewyearsagowhenshe realizedtheneedforacareerchange. Althoughherlongstandingaspiration wastoworkinrealestate,anintense fearofrejectionhadheldherback.

However,duringthechallengingtimes ofthepandemic,Uttleyengagedin deepself-reflection,ultimately decidingtoovercomeherfearand pursueherdreamjobwithunwavering determination.Despitefacingmultiple cancellationsofherrealestateexam duetoCovid-19,Uttley’sindomitable spiritledhertoembarkonajourney, emergingtriumphantasshepassed withflyingcolors.

UnleashingDetermination

Iftherewereabookchronicling Uttley’slifestory,itwould undoubtedlybetitled“TrueGrit,”a testamenttoherextraordinary determinationtogiveherallin everythingsheundertakes.Shehas facednumerousobstaclesand setbacks,butshehasconsistently pickedherselfup,dustedoffthe setbacks,andforgedahead.

Thedemandingnatureofherroleasa Realtorrequireshertoworktirelessly, dedicatingherselftoherclientsseven daysaweekandalwaysbeingoncall. Uttley’sdedicationisevidentinher willingnesstodropeverythingto accommodateherclients’schedules,

ensuringthattheyhaveevery opportunitytoviewpropertiesof interest.

Beingasuccessfulrealtornecessitates amultitudeofskills,andUttley possessestheminabundance.From marketingprowessandproblemsolvingacumentoanin-depth knowledgeoftheindustry,exceptional negotiationskills,ethicsandintegrity, sheembodiesthemultifacetednature oftheprofession.Despitethe challengesthatcomewiththejob, Uttleywholeheartedlyloveswhatshe does,andherenduringtenacityallows hertothriveinthedemandingworldof realestate.

EntrepreneurialRoots

Uttley’sentrepreneurialspiritwas deeplyinfluencedbyherpersonallife experiences.Growingupinafamilyof entrepreneurs,shewitnessedfirst-hand thedeterminationandresilience requiredtosucceedasasmallbusiness owner

Shesays, “I jumped in head first and did not hold back. Considering ninety percent of realtors fail in the first few years of business, I have done exceptionally well. My strong business sense and entrepreneurial spirit helped me to launch a successful business.”

Unlikeherpreviousroles,whereshe feltcompelledtohidehercreativity andvulnerability,Uttleymadea consciousdecisiontoletherauthentic selfshineinherrealestatecareer.By embracinghertruenature,shehas forgedgenuineconnectionswithher clients,approachingeachinteraction withawealthofknowledge,wisdom, andkindness.

EmbracingAuthenticity

Inhindsight,Uttleyreflectsonthe adviceshewouldgiveheryounger self:tobetrueandauthentic.Growing

up,herstrongsenseofempathyledher toprioritizethefeelingsofothersabove herown.Seekingacceptanceandtrying tofitin,shelosttouchwithhergenuine self.Theconstantpursuitofapproval causedhertoneglectherownneedsand desires.

Thishasproventobetransformativein herrelationshipsandbusinessendeavors. Bystayingtruetoherownvaluesand beliefs,Uttleyhasfostereddeeper connectionswithothers.Herempathy hasallowedhertoconnectwithpeople onagenuinelevel,understandingand resonatingwiththeiremotions.

Shehasfoundfulfillmentinbothher personalandprofessionallife.Her commitmenttobeingtruetoherselfnot onlyallowshertomakeapositive impactonothersbutalsofostersasense ofself-acceptanceandinner contentment.

FromVisiontoMilestones

Uttleyhadaclearvisioninmind:to createcreativemarketingthatstandsout fromthecrowd.Herson,atalented filmmaker,returnedhomeduringthe pandemic,lendinghisexpertiseto producecaptivatingvideosthatmade wavesonsocialmedia.Shesays, “Grateful for his assistance, I launched my business, forever indebted to his contribution.”

However,herapproachdidn’tstopat captivatingvideos.Despiteinitial skepticismfromherBusinessCoach,she hadthecouragetoinfusehermonthlyENewsletterwithpersonaltouches. Sharingherpassionforyogaandthe innerstrengthitcultivated,Uttley touchedtheheartsofherreaders.Ina serendipitousturnofevents,one recipientforwardedtheNewslettertoa fellowyogiwhoultimatelyentrusted Uttleywiththesaleofaremarkable$1.2 millionproperty.

CoverStory

Today,Uttleystandsonthecuspofa remarkablemilestoneinhercareer. Withherupcomingclosings,shewill celebrateher50thsuccessfullyclosed transactioninjustovertwoyears. Notably,heraccomplishmentsextend beyondresidentialproperties,asshe recentlysecuredherfirstcommercial buildingsale,pushinghertotalsales toapproximately$22million. Moreover,she’sactivelyengagedin twoothercommercialtransactions thathavethepotentialtomorethan doublehersalesrecord.

Uttley’stenacityhasnotgone unnoticed,assherecentlyreceived theprestigiousDirectorsGroup Awardforsalesvolume,ranking amongthetop10%ofMinnesota’s 18,000realtors.Fuelledbyher fearlessapproach,shehasthrown herselfwholeheartedlyintotheworld ofrealestate,devotingherutmost energyanddeterminationtoevery endeavor

Sheadds, “My strong work ethic, steadfast determination, and innate ability to connect with people has catapulted me into the top 10 percent of all realtors in Minnesota.”

Gratitudestemsfromthepersonaland professionalgrowthshehas experienced,whilejoyarisesfromthe privilegeofbeingapartofherclients’ uniquejourneys.Unfazedbythefear offailure,Uttley’senthusiasmfor participationhaspropelledherto remarkableachievements.

RejectionasaCatalyst

Uttleyunderstoodthatsuccessinher fieldrequiredputtingherselfout there.Shesays, “Rejection became a frequent companion, an inherent part of the job. Rather than succumbing to its painful sting, I chose to turn rejection into a game of growth and learning.”

Forthirtyconsecutivedays,she challengedherselftoseekrejectionat leastoncedaily Thisunique experimentallowedhertofacethe fearandshameassociatedwith rejectionhead-on.Insteadof avoidingorfearingit,sheembraced rejectionasanopportunityfor personalandprofessional development.

Hershiftinmindsetprovedpivotalin herjourney.Byreframingrejection asasteppingstonetowardsgrowth, shefosteredresilience.Eachrejection becameavaluablelesson,propelling herforwardinherrealestatecareer Bytransformingrejectionintoa gameofgrowth,shenotonly overcameitsnegativeeffectsbutalso harnesseditspowertobecomea strongerandmoresuccessfulrealtor.

DefyingStereotypes,Building Community

Uttley’srealestateambitions transcendtraditionaltransactions. Shesays, “I aspire to sell hotels and prove my worth in a male-dominated industry.” Determinedtodefy stereotypes,sheharnessesthefire withinhertoovercomechallenges andshowcasehercapabilities. Hercommitmenttohercommunity shinesthroughheractsofkindness. Whenshediscoveredbareshelvesat herlocalFoodShelf,shetook immediateaction.Organizinga neighborhoodfooddrive,sherallied hergenerousneighbors,resultingin anoutpouringofsupport.

Yearafteryear,theeventgrows, collectingincreasingamountsoffood toaddresshungerinhercommunity Additionally,Uttleyactivelysupports thelocalWomen’sShelterthrough herinvolvementintheGivingCircle, providingwomenandtheirchildren withasafeplacetoliveandthrive..

ForUttley,successgoesbeyond businesstransactions.Itliesinmaking apositiveimpact,andhelpingfamilies inhercommunity Through determination,empathy,andasteadfast commitmenttoservice,she exemplifiesthepowerofdefying stereotypesandbuildingabetterfuture forall.

Word of the wise

Do not wait for the right opportunity. Create them. After college, Uttley worked at the Hotel del Coronado, waiting on several celebrities, including Bruce Willis, who invited her to a party he hosted at the hotel. She has regretted not going, but she lacked self-confidence.

Uttley said she missed many other opportunities because of self-doubt.. For years she believed that there were a finite number of opportunities. However, she has since learned that the world changes every minute, and new opportunities show up daily. If you missed the last one, another is just around the corner.

Believing in yourself is one of the most important steps to learning how to identify and embrace opportunities. They rarely happen while in our comfort zone. Having the confidence to engage with new people and situations and try new things opens the door to possibilities beyond your wildest imagination.

ALL YOU NEED TO KNOW BEFORE VISITING

B B

Backinmychildhood,oneofmy friendsgiftedmeakeychainofthe EiffelTower.Iwassoawestruckbyits sheerbeautythatIcouldn'ttakemy eyesoffit.Istartedresearchingaboutit ontheinternetandgottoknowabout theEiffelTowerinParis.Sincethen,I havebeencuriousaboutthemonument andwantedtoexploresome enchantingsecretsregardingthesame.

ThisUNESCOWorldHeritageSitehas afascinatinghistoryandstunning architecture.Youcanunraveltheallure oftheEiffelTowerinPariswithme throughthisarticletodiscoversome mesmerizingfactsandinsightsabout it.Moreover,throughthisarticle,you willunlockthedynamichistorical backgroundofthetowerandknow moreaboutthelavishhotelstostay nearthemagnificentEiffelTowerin Paris.

VibrantHistoricalBackground

EiffelTowerorLaTourEiffelin French,isaneminentsymbolofParis andoneoftheworld'smost recognizablelandmarks.Gustave Eiffel,aFrenchengineerandhisteam constructedthetowerin1889forthe occasionofExpositionUniverselle (World'sFair)whichwasheldinParis tocelebratethe100thanniversaryof theFrenchRevolution.Theheightof theEiffelToweris330metersanditis thetallestman-madestructureatthat time.Despitefacingcriticismfrom citizensforwastingmoney,thetower wasacclaimednotonlywithinFrance butalsoattheinternationallevel.

Severalglobalfilmmakerscravefor shootingfilmsorsongsneartheEiffel TowerinParis.Itisoneofthemost visitedmonumentsworldwideand attractsmillionsoftouristseveryyear. Byservingasapowerfulsymbolof Parisianbeauty,theEiffelTowerstands asatestamenttohumaningenuity.Its richhistoryandtimelessbeauty continuetocaptivatevisitorsfrom aroundtheworld.

UnveilingFascinatingFactsabout EiffelTower

Beingoneofthemosticonic landmarksintheworld,theEiffel Towerenduresnumerousintriguing secretsandcaptivatingstoriesthatwill blowyourmind.Hereareafew interestingfactsaboutthisarchitectural marvel:

1.EiffelTowerusedtolookyellow earlier

E I F F E L T O W E R

Aftereverysevenyears,60tonsof paintisappliedtothetowertomakeit lookyoungforever

2.EiffelTowerusedtobetheworld's largestbillboard

During1925-1936,duskfellacross Parisandquartermillionbulbs attachedtoitssidewereilluminatedto spellthenameoftheFrench automobilecompanyCitroën.The advertisementincluded100-foot verticleletterswhichwerevisiblefrom 20milesaway

3.ThePetitionagainstEiffelTower inParis

EiffelToweriswidelyrecognizedas thesymbolofromance.However, artistsfromParisclaimthatthedesign ofEiffelTowerwasnotoriginal.A petitionwasfiledby300peoplethat includepainters,artists,sculptors,etc. Theycalledita“giganticblackfactory chimney”thatevencommercialmindedAmericadoesnotwanttobuy andtheyfiledthepetitionin1887on theoccasionofValentine'sDay

4.Hometoascientificlaboratory

Namesof72Frenchscientistsare engravedontheEiffelTowerandon thetoplevel,ascientificlaboratory wasinstalled.Scientistsusedtostudy anatomy,astronomy,meteorology, physiology,etc.byexperimentingin thelab.Eiffelinstalledan aerodynamicswindtunnelin1909at thebasetochecktestsofexperiments.

5.Itwassupposedtobetorndown after20years

Theintentionbehindbuildingthe EiffelTowerinPariswastoshowoff theindustrialprogressofFranceand destroyitafter20years.TheFrench governmenthaddecidedtodemolishit byestablishingaradioantennaand

wirelesstelegraphtransmitterinthe tower.However,thankstoits increasingpopularityamongmasses, thatdidn'thappen.

HiddenGemsnearEiffelTower

Undoubtedly,EiffelTowerisan impeccableexampleofan architecturalmonument.However, youcanvisitsomeotherplacesnear itonceyouareinParis.Thesegems giveyouanunforgettableexperience thatwilladdmoretoyourEiffel Towertrip.

1.MuséeduQuaiBranly-Jacques Chirac:Inthismuseum,youwill findinformationabouttheartand civilizationsofAfrica,Asia,Oceania, andtheAmericas.Ithaspreserved variousartifactsandculturalobjects aroundtheworld.

2.TrocadéroGardens:Itislocated justacrosstheSeineRiverwithina fewstepsfromtheEiffelTower The Gardensofferexcitingviewsofthe towerfromwhichyougetthebest picturestopostonsocialmedia.The fountainnearthegardengivesyoua soothingfeelingandthelightsinthe waterareatreattotheeyes.

3.ChampdeMars:Itisavastgreen spacethatstretchesfromtheEiffel TowertotheÉcoleMilitaire.Ifyou arelookingforanidealpicnicspot, thisistherightchoiceforyou.Along withenjoyingtheiconicviewofthe tower,youcanhaveastrollthere.

4.MuséeRodin:Itshowcasesthe workoffamoussculptorAuguste Rodinandissituatedinabeautiful mansionnearEiffelTowerinParis. Theextensivecollectionofthe museumincludesiconicsculptures like“TheThinker”and“TheKiss,” setamidstaserenegarden.

5.Invalides:Itisestablishedatashortdistancefromthe EiffelToweranditisacomplexofbuildingsthathouses severalmuseumsandmonuments,includingtheMusée del'Armée(ArmyMuseum)andthetombofNapoleon Bonaparte.

BestHotelstostaynearEiffelTower

TherearedistinctotherattractionsnearEiffelTowerin Paris.IfyouwanttostaynearEiffelTower,youshould beawareofthesehotelsthatarelocatedinitsproximity

E I F F E L T O W E R

Ÿ BulgariHotelParis:Thehotelis thelatestjewelintheGolden TriangleoftheCityofLightsthat islocatedelegantlynearAvenue GeorgeV.Ithasavibrantbarand loungethattakescareofthetaste ofeverykindofguestatthe internationallevel.Thepenthouse providesapersonalbathroom, bathtub,coffeemachine,minibar, safetydepositbox,etc.toenjoya lavishstayatthehotel.Itis1.2 milesawayfromtheEiffelTower

Ÿ MaisonVilleroy:Thepropertyis locatedinParisandgrantsallergyfreeroomsandrestaurants.You canhavefreeWiFieverywhere andenjoyacomplimentary breakfast.EiffelTowerisa16minutewalkfromthehotel.Spa andwellnesscenterservicesare thecherriesonthecakehere.

Ÿ Relais12bisBed&Breakfastby EiffelTower:Thehotelis500m awayfromtheEiffelTowerand situatedonthe1stfloorofthe building.Itsroomsare individuallydecoratedandit includescontemporaryfurniture thatgoeswiththetasteofguests. Yougetthefacilityofluxury toiletries,ahairdryer,abathrobe, andslippers.Dinneratits restaurantsmatchestheexperience ofhavingdinnerattheEiffel Tower

Ÿ RésidenceCharlesFloquet:The hotelislocatedintheheartof Parisandis50mawayfromthe EiffelTower.Inevery accommodation,youwillfinda balconyforeveryroom, comfortablebeds,andminibars. TheHotelisrenovatedbygiving historictouchtoit.Everyroom providesapicturesqueviewofthe EiffelTower

TipsforVisitingEiffelTower

GoingforaParistripandcoming withoutvisitingtheEiffelToweris somethingthathappensveryrarely! ButbeforeplanningyourParistrip, youshouldknowwhatprecautions needtobetaken.Hereistheessential informationyoumustknowbeforeyou visittheEiffelTowerinParis.

Ÿ TheIdealtimetovisitEiffelTower isintheearlymorningafter9.30 am.Ittakesmostly1to1.5hrsto seeEiffelToweroverall.Thenyou canhavebreakfastorlunchat MadameBrasserie,onthefirstfloor oftheEiffelTower.

Ÿ YoucanusetheParistravel guidebooktoavoidtimedelaysand mismanagement.Itwillenrichyour tripexperienceandcreate memories.Itisadvisedtouse comfortablewalkingshoesand wearlightweightclothesinaddition tocarryingaselfiestickandthe camera.

Ÿ Itisimportanttogetthe'museum pass'onedaybeforeifyouare planningtovisitmanyplaces withinlessduration.The'citypass' givesyoutheextraadvantageof freetransportoryoucanbooka privatecabasperyour convenience.

Ÿ Itisbettertobuyonlineticketsto EiffelTowersothatyoudon'thave towaitinalongqueueforalong time.Furthermore,youcangeta tourguidewhowillexplain everythingindetailaboutEiffel TowerinParis.

TheConcludingNote!

EiffelTowerinParisisamarvelof engineeringandthemostacclaimed monument.Itscaptivatingbeautyand historicalsignificancehavemadeita must-visitdestinationfortravelers aroundtheglobe.Fromitsstunning

viewstoitsintricatedesign,theEiffel Towercontinuestoinspireaweand admiration.Wehopeyouenjoyed readingourblogandreceived importantinsightsonEiffelTower

FAQsrelatedtoEiffelTowerinParis

1.Whatisthenearestbusand railwaystationtoEiffelTower?

“ChampdeMars-TourEiffel.”isthe nearestbusstationaswellasarailway stationfromtheEiffelTower.Itis locatedatwalkingdistancefromthe landmarkandyouwillfindthemost convenientstationtoreachEiffel Tower.

2.HowoldisEiffelTower?

EiffelToweris130yearsoldandone ofthemostdistinctivesymbolsofnot justthecapitalcityofParisbutalso everyFrenchcitizen.

3.WhatisParisfamousfor?

InadditiontoEiffelTower,Parisis famousforLouvreMuseum,and Notre-Damecathedral.Duringyour vacationsinParis,youcaninclude thesetouristspotsinyourlist.

KATHY COLVILLE

LEADING WITH PURPOSE

Kathy Colville and Associates | Owner

KathyColvilleisadistinguished realtorandaleaderinherfield, inspiringwomentobreakbarriersand shatterglassceilingsintherealestate industry.CIOWomenMagazineis proudtointroducehertoTheMost InfluentialWomenLeadersInReal Estate.

Effectivecommunicationisahallmark ofleadership,andaleaderwhocan conveytheirmessageinaclear, concisemannercaninspireand motivatetheirteamtoachievetheir goals.Patienceisanothercrucialtrait, asitallowsaleadertoremaincalmand focusedduringtimesofstressand uncertainty.

Leaderswhopossesskeenattentionto detailcanidentifyandrectifypotential problemsbeforetheybecomemajor issues.Additionally,aleaderwhois attentivetotheirclients'needscan buildtrustandconfidence,ultimately leadingtoincreasedsatisfactionand loyalty

Thesequalitiesareparamountinthe fast-pacedandever-changingworldof realestateaswell,wheresuccess dependsonbuildingstrong relationshipsanddelivering exceptionalservice.Kathy'ssuccessin therealestateindustryisatestamentto herleadershipqualitiesandher

commitmenttoprovidingexceptional servicetoherclients.

KWheredidthejourneybegin?

KathyColvilleisasuccessfulrealtor withover37yearsofexperienceinthe industry.Herjourneyasarealestate agentbeganin1986,shortlyafter decidingtosellhercondoandmove intoasingle-familyhomewithherfirst husbandandtwosmallchildren.Kathy decidedtobecomealicensedreal estateagenttostaycurrentwiththe housingmarket. Aftercompletingtherequiredcourses andpassingtheexam,Kathyjoined TownandCountryRealEstatefirm, whereshequicklylearnedthatholding openhouseswasthebestwaytoattract buyers.Sheheldopenhousesforany homeinthefirst-timebuyer’sprice rangeandsoonhadherfirstclient, whichledtoherbecomingafull-time professionalrealtor.Herhardworkand dedicationearnedhertheRookieofthe YearawardandaspotintheDAAR MillionDollarClub.

KathypursuedtheGraduateRealtor Institute(GRI)andCertified ResidentialSpecialist(CRS) designationstofurtherherknowledge andexpertise.Shethenjoined REMAXSELECTProperties,where shelearnedfromtoprealtorsinthe businessandsurroundedherselfwith mentorstoguideheralongtheway

AsKathy'svolumeandnumberof homessoldgrew,sherealizedshe neededhelptotakeherbusinesstothe nextlevel.Shebecameoneofthefirst agentsinherareatohireanassistant andstreamlineheroffice,which allowedhertostartherfirstteam, KathyColvilleandAssociatesLLC. Herteamcontinuedtogrowand prosper,helpingover2,700families findorselltheirdreamhomes.

In2018,KathyjoinedCentury21 RedwoodRealty,whichprovidedher withthecutting-edgerealestate technologyneededtoadapttotheeverchangingindustry.Herdedicationand hardworkearnedherfiveDouble CenturianawardswithC21Realtyand aspotintheTop500Realtorsinthe NorthernVirginiaarea.Sheisalsoone ofthetop1%ofrealtorsinthecountry, holdingapositionintheTop5Real EstateCompaniesintheUnitedStates andnumber1inVirginia.

Evenduringthepandemic,Kathy's teamcontinuedtothrivebyadaptingto virtualappointments,videoshowings, andmaintainingexcellent communicationthroughouttheprocess withfamilies.In2020and2021,her teamhadtwooftheirbestyearsyet.

KathyColville'sjourneyasarealtoris oneofhardwork,dedication,and perseverance.Hersuccessisa testamenttoherpassionforhelping familiesfindtheirdreamhomesand herwillingnesstoadapttotheeverchangingindustry

DefiningWork-LifeBalance

Inher37yearsofexperienceinthe realestateindustry,Kathyhaslearned tomaintainahealthywork-life balance.Sheunderstandsthe importanceofspendingtimewithher familyandmakesaconsciouseffortto taketimeoffworkforthatpurpose.

However,herpassionforherwork ensuresthatevenwhileatwork,it neverfeelslikework.Kathy's dedicationtoherclientshashelpedher buildlong-lastingrelationshipswith them,andtheyhavebecomemorethan justbusinessassociatesbutalso friends.Spendingtimewiththemisnot onlyapleasurebutalsoapartofher jobthatshethoroughlyenjoys.

TheGameChanger

KathyColvilleandAssociates

LLC(KCA)isarenownedreal estateteam,consistingofof sevenexperiencedrealtorsand twofull-timeassistants.Witha missiontokeepclientsforlife, thefirmhasearnedareputation foritshighlevelof professionalismand communication.

TheKCAteamunderstandsthat buyingorsellingapropertycan beanoverwhelmingexperience, andthus,theystrivetoprovide theirclientswiththebestpossible experience.Theyworkclosely withclientstounderstandtheir needsandprovidecustomized solutionsthatmeettheirunique requirements.

Theteam’s'scommitmentto keepingclientsforlifeisevident intheexceptionalservicethey provide.Theteamgoesaboveand beyondtoensurethattheirclients aresatisfiedwiththeirservices, andtheymakesuretomaintain communicationthroughoutthe buyingorsellingprocess.

KCAhasaproventrackrecordof success,withnumeroussatisfied clientswhohavereferredthe teamtotheirfriendsandfamily

Theteam’s'ssuccesscanbe attributedtoitscorevalues, whichincludehonesty,integrity, andacommitmenttoexcellence.

Inadditiontoprovidingtop-notch realestateservices,theKCAteam alsobelievesingivingbacktothe community.Theyareactively involvedinvariouscharitable causesandorganizations,and theybelievethatgivingbackisan essentialpartoftheirbusiness.

My team is unique because I allow the individual agents to brand themselves as well as being part of the total team.

Withtheirextensiveknowledgeofthe realestatemarketandcommitmentto keepingclientsforlife,theyarethe perfectpartnerforallyourrealestate needs.

Roadblocks

Inthebusinessworld,everysector facesitsuniquesetofchallengesand requirements.However,someissues canhaveaprofoundimpacton businessesacrossindustries. Successfulcompaniesmustnavigate

thesechallengestodifferentiate themselvesfromtheircompetitors, maintainqualitycustomer relationships,andensureemployee satisfaction.

KCAhasfacedsimilarchallengesinits pursuitofexcellence.In1994,when Kathyhiredherfirstassistant,the practicewasnotyetcommonamong realtors.TheRealtorassociationswere unsureofhowtoincorporateassistants intothecodeofethicsandwhattasks theycouldperformforagents.

Nevertheless,Kathyworkedwithher brokerandtheassociationsto demonstratethebenefitsofhavingfulltimeofficestaffhandletheeverchangingpaperworkandprocesses, whichwasawinforboththecompany anditsclients.

Long-standingsuccess

KathyColvilleandAssociatesLLC, withareputationforexcellence,has enjoyedlong-standingsuccessthanks toitsunwaveringcommitmentto treatingclientslikefamily

Withaphilosophycenteredonrespect, theteamofrealtorstreatseachclient's moneyanddecisionsasiftheywere theirown,andstaysintouchlongafter thetransactioniscompletetooffer continuedvalue.

Thisapproachhasledtoaloyalclient basewhoreturnyearafteryear,aswell asprovidevaluablereferralstofriends andfamily Thefirm'ssuccessisa testamenttoitsdedicationtoproviding exceptionalserviceandbuildinglonglastingrelationshipswithitsclients.

Teamforthewin

Asuccessfulfirmisbuiltonthe foundationofastrongteam,andthisis especiallytrueforarealestateteam likeKathyColvilleandAssociates LLC.Theteamconsistsofseven experiencedrealtorsandtwofull-time assistants,allofwhombringunique skillsandperspectivestothetable.

Byworkingtogethertowardsa commongoalofprovidingthehighest levelofprofessionalismand communicationtotheirclients,the teamisabletoachievegreatersuccess thananyindividualcouldalone.

Theteamplacesgreatvalueon creatingapositiveandsupportivework

environmentwhereeveryonefeels valuedandempoweredtocontribute theirbestwork.Theteam's commitmenttoexcellenceandtheir willingnesstocollaboratewitheach otherisreflectedintheteam’s'slongstandingsuccess.

Settingitapart

KathyColvilleandAssociates,a licensedrealestateteamserving clientsinVirginia,WestVirginia, Maryland,andWashingtonDC,is committedtomeetingthe continuouslychangingdemandsof itsclients.Theteamunderstandsthe importanceofmaintainingvarious modesofcommunicationsuchas email,socialmedia,text,andvideo conferencingtoensureseamless interactionswithclients.

Tostayabreastoftheevolvingtrends andtechnologies,KathyColvilleand Associatesincorporatestechnology intoitsofferings.Thefirmleverages varioustoolsandplatformsto provideitsclientswithinnovative solutionsandbetterservices.By adoptingnewtechnologies,Kathy ColvilleandAssociatesremains competitiveandabletodeliverthe bestresultstoitsclients.

Kathyadds,“Wehaveagrowing socialmediapresenceinallareas.All formsarenowonline,andsentfor signatureselectronically,which allowsformoregrowth.”

Astepahead

KathyColvilleandAssociatesLLC hasalwaysbeenforward-thinkingin itsapproachtorealestate,andithas showninitscontinuedsuccess.With itsclientsattheforefront,theteamis nowtakingthenextstepinits journey

Thenextstepfortheteamistotrain inbranding,withafocusongrowingall areasofsocialmedia.Thisstepwillallowtheteamtocreateastrongerbrand identityandfurtherengagewithitsclientsthroughsocialmediaplatforms.By stayingup-to-datewiththelatesttrendsintechnologyandmarketing,thefirm iscommittedtoprovidingthehighestlevelofserviceandsupporttoitsclients.

Wordofthewise

KathyColville Owner

Focusonwhatmakesyouunique,notwhatsocietyexpectsyoutobe.

AI TOOLS ARE FINALLY CHANGING THE

BIOPHARMA LANDSCAPE

BIOPHARMA

ThebiopharmaindustryAItools

arefinallychangingbecauseof howquicklyandhowmuch medicalandscientificprogressisbeing made.Newbusinessmodelsarebeing madebecausepatientswanttobemore involvedandhaveabetterexperience. Biopharma’snewcurrencyisdatathat ismade,captured,analyzed,andused inreal-timebynewmedicaldevices. Oneofthemostimportantthingsthat setcompaniesapartishowwellthey cangetinsightsandprooffrom multipledatasources.Sincethisisthe case,digitaltransformationisa strategicmust.Thisreportexplains howtechnologiesthatAItoolsare finallychanginguseartificial intelligencewillaffectthebiopharma valuechainandspeedupthedigital transformationofbiopharma. Eventhoughthereisalotof innovationintheindustry,biopharma companiesarefacingacomplexand difficultenvironmentduetomore competitionandlongerR&Dcycle times,lesstimeonthemarket,patents thatareabouttoexpire,fallingpeak sales,pressurearoundreimbursement, andmorescrutinyfromregulators.As we’veshowninourseriesofreportson “Measuringthereturnfrom pharmaceuticalinnovation,”these factorsarecausingtheprojectedreturn oninvestmentthatlargebiopharma companiescouldgetfromtheirlatestagepipelinestodropbyanalarming amount,whichthreatenstheirlongtermfuturesAItoolsarefinally changing.

HerearesomewaysthatAItoolsare finallychangingtheworldof biopharma:

Somebiopharmacompanieswanttheir chiefinformationofficers(CIOs)to leadtheirdigitaltransformationefforts, whileothershavehiredchiefdigital officers(CDOs),whoareoftenfrom otherindustries,orchiefdigital

informationofficers(CDIOs),who combinemanyoftheskillsofaCIO andaCDO.

Ÿ AItoolsarefinallychanging

Ÿ scientificprogress

Ÿ Artificialintelligence

Nomatterwhattheirjobtitleis,those inchargeofdigitaltransformationin biopharmacompaniesneedtousedata andnewdigitaltechnologiestothe fullesttochangetheirbusinessand operatingmodels.Themostanticipated andimportantofthesetechnologiesare thosethatfallundertheterm“AI.”

Atthemoment,machinelearning(ML) isthemostimportantpartofmanyAI technologies.Recentimprovementsin MLalgorithmsandthemore complicatedpartofMLcalleddeep learning(DL)arewhataregetting peopleexcited.Untilrecently,many companiesdidn’thavetheskillsto makethemostofAItoolsarefinally changing.Thisisbecausefindingthe rightusecases,makingcustom solutions,andusingthesesolutionsat thescalerequiredaccesstolargedata sets,specializedinfrastructureand processingpower,andateamofdata andanalyticsexperts.7Usingitona largescalealsorequiredalotofmoney tobespent.

Today,thisisquicklychangingastech giantsandstart-upsthatwereearlyto useAIofferAI-baseddevelopment toolsandappsasproductsand services,sothatothercompaniescan alsouseAI.Biopharmacompanies haveaccesstolargedatasets,andthe resourcestogetthecomputingpower andtoptechnicaltalenttheyneedand areinagoodpositiontoprofitfromAI iftheyinvestearlyAItoolsarefinally changing.

1.ThemarketforAIinbiopharma

MarketsandMarketspredictsthatthe marketforAItoolsarefinallychanging inthebiopharmaindustryandwill growfrom$208millionin2018to $3.88billionin2025,whichisa compoundannualgrowthrate(CAGR) of52.9%.

8Thesevaluesaredifferentineachof thefourregions:NorthAmerica, Europe,Asia-Pacific(APAC),andthe RestoftheWorld(RoW),which includesSouthAmerica,Africa,and theMiddleEast(seefigure3).

Between2018and2025,itisexpected thatdrugdiscovery,precision medicine,medicalimagingand diagnostics,andresearchwilldrive mostoftheAItoolsthatarefinally changinginbiopharma.Duringthe periodoftheforecast,drugdiscovery willbethebiggestmarket.Itwillgrow from$159.8millionin2015to $2,999.7millionin2025,whichisa CAGRof52.0%.Overthenextfive years,themarketforprecision medicineisexpectedtogrowby60.2% peryear,from$16.3millionin2018to $440,9million.CAGRsofover50% arealsoexpectedformedicalimaging anddiagnosticsandresearch(see figure4).

2.ThingsthataremakingAIgrow acrossthevaluechain.

ThegrowthofglobalAItoolsare finallychanginginbiopharmaandthe potentialfordigitaltransformationare causedbyseveralthings.Froma technologyanddatapointofview, transformationisbeingdrivenbythree thingsinparticular:moredata,more powerfulcomputers,andcheaper computers.

3.Biopharma’sfuturewillbedriven byAI

Biopharmacompanieswilluse technologiestospeedupinnovation, streamlineprocesses,andgetridof

barriersasaresultofdigital transformation.AItechnologieswillbe attheforefrontofthischange.They willhelpimproveefficiency,power newproductsorservices,enablenew businessmodels,andcreatea biopharmaindustrythatisvery differentfromwhatitisnowAItools arefinallychanging.

4.AIwillaffecteverypartofthe biopharmaceuticalvaluechain.

AIwillaffectthewholebiopharma valuechain.Atfirst,itwilldothisby collectingandcombininginformation fromdata(seefigure15).Hereare someexamplesofhowAIcouldbe usedinthedifferentpartsofthevalue chainAItoolsarefinallychanging.

5.Researchandfindout

UsingAIandcomputationalbiologyto findnewdrugsandmakethembetter couldmakeahugedifferenceinhow productivepeopleare.Inturn,thiswill makeresearchanddiscoveryless expensive,faster,andbetter.Itwillcut downonthenumberofdrugsthat don’tworkbyfindingpatternsinalot ofdata.Itwillalsoimprovetarget identification,safetyandeffectiveness assessments,andmodelingthat predictswhatwillhappenand“testing inthecomputer.”

OneimportantthingthatAItoolsare finallychangingispredictinghow moleculeswillinteractwitheachother Thishelpsusfigureouthowdiseases work.Inturn,thesemechanismscould helpfindnewbiomarkers,find,design, validate,andoptimizenewdrug candidates,andfindexistingdrugsthat couldbeusedforotherpurposes.

CombiningAIwithothertechnologies likeorgan-on-a-chip,3Dcellcultures, andothercellmodelsthatmimic humanbiologyin-vitrocouldreduce theneedtotestonanimalsandcould eventuallyleadtotheendofPhase1

clinicaltrialsinhealthyvolunteers.

Atthemoment,over148start-up companiesandover33large biopharmacompaniesareusingAIto researchandfindnewdrugs.Theydo thisthroughpartnershipsorontheir own.

40–41.Companiesarealsolooking intothepossibilityofusingAIto designandrunpreclinicalexperiments, whichcouldhelpcutdownthetimeit takestofind,develop,andreleasea newdrugAItoolsarefinallychanging.

6.Clinicaldevelopment

Clinicaltrialsarereadyforchange becausetheyaretakinglonger,cost more,andhavealotofmanualsteps. Also,alotoftrialsareneverfinished. ClinicalTrials.govwasusedtoregister morethan30,000clinicaltrialsin 2018.Sincetheyear2000,nearly 300,000trialshavebeenregistered. Butlessthan5,000trialsreportedtheir resultsin2018,andsince2000,less than35,000registeredstudieshave reportedtheirresultsAItoolsare finallychanging.

Biopharmacompaniesarecurrently lookingintohowtheycanuseAI technologytoimprovetheirclinical trials.Thisincludesimprovingtrial designandpatientrecruitment, analyzingbothtrialresultsand evidencefromtherealworld,and automatingthepublicationofresultsto makeitfasterandmoreefficient.Ifthe implementationgoeswell, developmentcostscouldgodown, peoplewouldbemorelikelytofollow therules,andtheresultswouldbe better&AItoolsarefinallychanging.

Also,havingaccesstolargeamounts ofdataandAI-poweredanalyticscould leadtothecreationofhighlyeffective personalizedtherapieswithouttheneed forlarge-scaleclinicaltrials.

7.Makingthingsandgetting supplies

Biopharmamanufacturingandsupply chainscreatealotofreal-timedatathat hasn’tbeenusedinausefulwayfor manyyears.ButAItoolsarefinally changingtechnologiesthatcould changetheseprocessesbyprocessing andmakingdecisionsaboutdatainreal time.Thiscouldmakesupplychains trulydata-driven.Thepotentialfor end-to-endvisibilityinmanufacturing andsupplychainswillhelpbiopharma companiesimprovetheirsupplychain planning,inventorymanagement, demandforecasting,logistics optimization,workforceplanning,and purchasing.

Biopharmacompanieswillbeableto managetheirsupply,quality,safety, security,andcostsbetteriftheycan changeprocessesandtrack medicationsinreal-time.Thiswilllead tosmartermanufacturingandsupply chaindecisions.

Thebusinessworldislikelytomove awayfromlinearsupplychainsand towarddigitalsupplynetworksthatare open,flexible,andlinked(DSNs). DSNsusedigitaltechnologieslike sensors,roboticprocessautomation (RPA),blockchain,andadvanced analyticstoimprovethevisibility, traceability,andcontrolofproducts andinventory.MLappliedto productiondatatobuildcompliance andqualityriskmodelsthathelp predictfailuresandcompliance problemsisalreadyhelpingseveral companies.Atthesametime,RPAand NLPcouldautomatethecreationand filingofcompliancereportsAItools arefinallychanging.

Cellandgenetherapies,whichare examplesofnext-generationproducts, willprobablyneedadifferentsetof skillstomakeandshipthantraditional molecules.Thesecapabilitiesshould

includeadvancedanalyticsand workflowautomationtomakeiteasy tocoordinatepatientcellcollection, manufacturingcapacity,coldchain logistics,anddeliveryofviable productstothetransfusioncenter

8.Launchandbusiness

Biopharmacompaniescouldbenefit greatlyfrombeingabletoseehow theirproductsaresoldfromstartto finish.UsingAIcanhelpcompanies planproductlaunchesbetter,get patientsmoreinvolved,helpdoctors makedecisionsandrunmarketing operations,andpredictdecisionsabout marketaccessandpricing.AItoolsare finallychangingandarealreadybeing usedtotrytoimproveengagementby customizingbehavioralnudgestoeach person’spersonality,motivations,care journey,andengagementchallenges.

Customizedengagementwith healthcareprofessionals(HCPs)could helpmakesurethattherightHCPsget therightinformationattherighttime. AIcanbeusedtodivideHCPsinto different“personas”basedontheir habits,preferences,andhowopenthey aretomarketingmessages.Tosupport reimbursementmodelsfornew curativetherapiesandservices,itwill likelybecomeimportanttogather evidencetoshowproofofvalueAI toolsarefinallychanging.

9.Post-marketsurveillanceand patient

supportprograms

Afteradrugisreleased,biopharma companiesmayalsoneedinteroperable healthdatatokeeptrackofpatients, communicatewiththemfroma distance,andofferthempersonalized treatmentoptionsattherighttime.For this,patientdatamustbeintegrated andanalyzedinreal-timetofigureout ifandwhenaninterventionisneeded. ItwillbeimportanttouseAIto improvesafety,especiallytofind

possiblebadthingshappeningorbad thingshappeninginreal-timeAItools arefinallychanging.

Itwillalsobeimportanttolearnmore aboutpatientmonitoringthanjust safety,andmanybiopharmacompanies andstart-upsarefocusingonthisarea. AI-poweredpatientsupportprograms couldchangethewaybiopharma interactswithitscustomers,improve enrollment,adherence,andretention, andimprovetheoveralloutcomefor patients.