Cell expansion market forecast to 2022 by scalar market research

Cell Expansion Market, by Products (Reagents, Media, Sera, Disposables, Bioreactors, Flow Cytometers, Centrifuges, Cell Counters), Applications (Regenerative Medicine, Stem Cell Research, Cancer Research), End-users (Hospitals, Cell Banks, Biopharmaceutical Companies, Research Institutes) – Global Market Size and Forecast to 2022

December 2016

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Table of Contents 1

MARKET OVERVIEW ......................................................................................................................14 1.1

Definitions.............................................................................................................................14

1.2

Research Methodology .........................................................................................................14

1.3

Market Segmentation ...........................................................................................................16

2

EXECUTIVE SUMMARY ..................................................................................................................17

3

MARKET DYNAMICS ......................................................................................................................18 3.1

Drivers ...................................................................................................................................18

3.2

Restraints ..............................................................................................................................19

3.3

Opportunities........................................................................................................................20 Increasing global geriatric population ..........................................................................20

3.3.2

High prevalence rate of chronic diseases .....................................................................20

3.3.3

Increased Healthcare Awareness..................................................................................20

5

Trends ...................................................................................................................................22 Rising healthcare expenditures across the world .........................................................22

3.4.2

Increasing use of cell expansion technology across varied therapeutic sectors ..........22

3.4.3

Expansion of cell banking and manufacturing facilities................................................22

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3.4.1

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3.4

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3.3.1

INDUSTRY ANALYSIS......................................................................................................................23 4.1

Value Chain Analysis .............................................................................................................23

4.2

Regulatory Landscape ...........................................................................................................24

CELL EXPANSION MARKET, BY PRODUCTS....................................................................................25 5.1

Segment Share ......................................................................................................................25

5.2

Global Cell Expansion Market, By Products ..........................................................................26

5.2.1

Reagents, Media, and Sera ...........................................................................................27

5.2.2

Disposables ...................................................................................................................29

5.2.3

Bioreactors ....................................................................................................................30

5.2.4

Flow Cytometers ...........................................................................................................32

5.2.5

Centrifuges ....................................................................................................................33

5.2.6

Cell Counters .................................................................................................................35

2

5.2.7

Segment Share ......................................................................................................................38

6.2

Global Cell Expansion Market, By Applications ....................................................................39

6.2.1

Regenerative Medicine and Stem Cell Research ..........................................................40

6.2.2

Cancer Research............................................................................................................42

6.2.3

Other Applications ........................................................................................................44

CELL EXPANSION MARKET, BY END-USERS ...................................................................................46 7.1

Segment Share ......................................................................................................................46

7.2

Global Cell Expansion Market, By End-users ........................................................................47 Hospitals and Cell Banks ...............................................................................................48

7.2.2

Biopharmaceutical Companies .....................................................................................50

7.2.3

Research Institutes........................................................................................................52

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7.2.1

CELL EXPANSION MARKET, BY REGIONS.......................................................................................54

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6.1

8.1

Segment Share ......................................................................................................................54

8.2

Global Cell Expansion Market, By Regions............................................................................55

8.3

North America.......................................................................................................................56

8.3.1

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CELL EXPANSION MARKET, BY APPLICATIONS ..............................................................................38

Cell Expansion Market in North America, By Regions ..................................................57

8.3.1.1

U.S. ............................................................................................................................58

8.3.1.2

Rest of North America...............................................................................................59

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Other Products..............................................................................................................36

8.3.2

Cell Expansion Market in North America, By Products.................................................59

8.3.3

Cell Expansion Market in North America, By Applications ...........................................61

8.3.4

Cell Expansion Market in North America, By End-users ...............................................63

8.4

Europe...................................................................................................................................65

8.4.1

Cell Expansion Market in Europe, By Regions...............................................................66

8.4.1.1

Germany....................................................................................................................67

8.4.1.2

U.K.............................................................................................................................68

8.4.1.3

France........................................................................................................................68

8.4.1.4

Rest of Europe...........................................................................................................69

8.4.2

Cell Expansion Market in Europe, By Products .............................................................69

8.4.3

Cell Expansion Market in Europe, By Applications .......................................................71

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8.4.4 8.5

Asia-Pacific ............................................................................................................................75

8.5.1

Cell Expansion Market in Asia-Pacific, By Regions ........................................................76

8.5.1.1

China .........................................................................................................................77

8.5.1.2

Japan .........................................................................................................................78

8.5.1.3

India...........................................................................................................................78

8.5.1.4

Rest of Asia-Pacific ....................................................................................................79

8.5.2

Cell Expansion Market in Asia-Pacific, By Products ......................................................79

8.5.3

Cell Expansion Market in Asia-Pacific, By Applications.................................................81

8.5.4

Cell Expansion Market in Asia-Pacific, By End-users.....................................................83

Rest of the World (RoW).......................................................................................................85 Cell Expansion Market in RoW, By Regions ..................................................................86

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8.6.1 8.6.1.1

Latin America ............................................................................................................87

8.6.1.2

Middle East and Africa ..............................................................................................88

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8.6

Cell Expansion Market in RoW, By Products.................................................................88

8.6.3

Cell Expansion Market in RoW, By Applications ...........................................................90

8.6.4

Cell Expansion Market in RoW, By End-users ...............................................................92

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8.6.2

KEY MARKET PLAYERS ...................................................................................................................94 9.1

Thermo Fisher Scientific Inc. .................................................................................................94

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Cell Expansion Market in Europe, By End-users ...........................................................73

9.1.1

Overview .......................................................................................................................94

9.1.2

Key Strategies................................................................................................................94

9.1.2.1

Focus on Product Innovation ....................................................................................94

9.1.2.2

Strategic Acquisitions and Partnerships to Strengthen Technological Capabilities..94

9.1.3 9.2

Recent Developments...................................................................................................94

Beckman Coulter, Inc. ...........................................................................................................96

9.2.1

Overview .......................................................................................................................96

9.2.2

Key Strategies................................................................................................................96

9.2.2.1

Strategic Market Expansion ......................................................................................96

9.2.2.2

Strategic Acquisitions and Partnerships to Strengthen Technological Capabilities..96

9.2.3 9.3

Recent Developments...................................................................................................96

Corning Incorporated............................................................................................................98

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9.3.1

Overview .......................................................................................................................98

9.3.2

Key Strategies................................................................................................................98

9.3.2.1

Product Innovation ...................................................................................................98

9.3.2.2

Strategic Collaborations and Partnerships................................................................98

9.3.3 9.4

Recent Developments...................................................................................................98

General Electric Company. (GE Healthcare) .......................................................................100

9.4.1

Overview .....................................................................................................................100

9.4.2

Key Strategies..............................................................................................................100

9.4.2.1

Focus on Technological Developments...................................................................100

9.4.2.2

Strategic Acquisition and Collaboration..................................................................100

9.4.3

Lonza ...................................................................................................................................102

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9.5

Recent Developments.................................................................................................100

Overview .....................................................................................................................102

9.5.2

Key Strategy ................................................................................................................102

9.5.2.1 9.5.3

Strategic Acquisitions to Expand their Capabilities ................................................102 Recent Development ..................................................................................................102

Merck KGaA. .......................................................................................................................104

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9.6

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9.5.1

Overview .....................................................................................................................104

9.6.2

Key Strategy ................................................................................................................104

9.6.2.1

Product Innovation .................................................................................................104

9.6.2.2

Strategic Acquisition, Collaborations and Partnerships..........................................104

9.6.3 9.7

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9.6.1

Recent Developments.................................................................................................104

Miltenyi Biotec ....................................................................................................................106

9.7.1

Overview .....................................................................................................................106

9.7.2

Key Strategy ................................................................................................................106

9.7.2.1 9.7.3 9.8

Strategic Acquisitions, Collaborations and Partnerships ........................................106 Recent Developments.................................................................................................106

STEMCELL Technologies Inc. ...............................................................................................107

9.8.1

Overview .....................................................................................................................107

9.8.2

Key Strategy ................................................................................................................107

9.8.2.1

Strategic Collaboration and Partnership.................................................................107

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9.8.3 9.9

Recent Developments.................................................................................................107

TERUMO BCT, INC. ..............................................................................................................108

9.9.1

Overview .....................................................................................................................108

9.9.2

Key Strategy ................................................................................................................108

9.9.2.1 9.9.3 9.10

Focus on Strategic Collaboration and Partnership .................................................108 Recent Developments.................................................................................................108

BECTON, DICKINSON AND COMPANY.................................................................................109

9.10.1

Overview .....................................................................................................................109

9.10.2

Key Strategies..............................................................................................................109

9.10.2.1

Focus on Product Innovation ..............................................................................109

9.10.2.2

Strategic Acquisitions and Partnerships to Strengthen Technological Capabilities 109

Recent Developments.................................................................................................109

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9.10.3

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10 SCALAR 360 DEGREE MARKET PERSPECTIVE ..............................................................................111

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11 APPENDIX ....................................................................................................................................112

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List of Tables Global Cell Expansion Market Snapshot ...........................................................................17

Table 2.

Global Cell Expansion Market Drivers...............................................................................18

Table 3.

Global Cell Expansion Market Restraints ..........................................................................19

Table 4.

Global Cell Expansion Market Size (US$ billion), By Products (2014 – 2022) ...................26

Table 5.

Global Reagents, Media, and Sera Market Size (US$ billion), By Regions (2014 – 2022).28

Table 6.

Global Disposables Market Size (US$ billion), By Regions (2014 – 2022).........................29

Table 7.

Global Bioreactors Market Size (US$ billion), By Regions (2014 – 2022) .........................31

Table 8.

Global Flow Cytometers Market Size (US$ billion), By Regions (2014 – 2022).................32

Table 9.

Global Centrifuges Market Size (US$ billion), By Regions (2014 – 2022) .........................34

Table 10.

Global Cell Counters Market Size (US$ billion), By Regions (2014 – 2022) ......................35

Table 11.

Global Other Products Market Size (US$ billion), By Regions (2014 – 2022) ...................37

Table 12.

Global Cell Expansion Market Size (US$ billion), By Applications (2014 – 2022) .............39

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Table 1.

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Table 13. Global Cell Expansion Market for Regenerative Medicine and Stem Cell Research, Market Size (US$ billion), By Regions (2014 – 2022) ............................................................................40

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Table 14. Global Cell Expansion Market for Cancer Research, Market Size (US$ billion), By Regions (2014 – 2022) ........................................................................................................................................43 Table 15. Global Cell Expansion Market for Other Applications, Market Size (US$ billion), By Regions (2014 – 2022) ..........................................................................................................................44 Table 16.

Global Cell Expansion Market Size (US$ billion), By End-users (2014 – 2022) .................47

Table 17. Global Cell Expansion Market for Hospitals and Cell Banks, Market Size (US$ billion), By Regions (2014 – 2022) ..........................................................................................................................48 Table 18. Global Cell Expansion Market for Biopharmaceutical Companies, Market Size (US$ billion), By Regions (2014 – 2022).........................................................................................................51 Table 19. Global Cell Expansion Market for Research Institutes, Market Size (US$ billion), By Regions (2014 – 2022) ..........................................................................................................................52 Table 20.

Global Cell Expansion Market Size (US$ billion), By Regions (2014 – 2022).....................55

Table 21.

Cell Expansion Market in North America, Market Snapshot ............................................56

Table 22.

2022)

Cell Expansion Market in North America, Market Size (US$ billion), By Regions (2014 – 57

Table 23.

Cell Expansion Market in U.S., Market Size and Annual Growth Rate (2015 – 2022) ......58

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Table 24. Cell Expansion Market in Rest of North America, Market Size and Annual Growth Rate (2015 – 2022) ........................................................................................................................................59 Cell Expansion Market in North America, Market Size (US$ billion), By Products (2014 – 60

Table 26.

– 2022)

Cell Expansion Market in North America, Market Size (US$ billion), By Applications (2014 62

Table 27.

2022)

Cell Expansion Market in North America, Market Size (US$ billion), By End-users (2014 – 63

Table 28.

Cell Expansion Market in Europe, Market Snapshot ........................................................65

Table 29.

Cell Expansion Market in Europe, Market Size (US$ billion), By Regions (2014 – 2022)..66

Table 30.

Cell Expansion Market in Germany, Market Size and Annual Growth Rate (2015 – 2022) 67

Table 31.

Cell Expansion Market in U.K., Market Size and Annual Growth Rate (2015 – 2022) ......68

Table 32.

Cell Expansion Market in France, Market Size and Annual Growth Rate (2015 – 2022)..68

Table 33.

2022)

Cell Expansion Market in Rest of Europe, Market Size and Annual Growth Rate (2015 – 69

Table 34.

Cell Expansion Market in Europe, Market Size (US$ billion), By Products (2014 – 2022) 70

Table 35.

2022)

Cell Expansion Market in Europe, Market Size (US$ billion), By Applications (2014 – 72

Table 36.

Cell Expansion Market in Europe, Market Size (US$ billion), By End-users (2014 – 2022) 73

Table 37.

Cell Expansion Market in Asia-Pacific, Market Snapshot..................................................75

Table 38.

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By Regions (2014 – 2022) 76

Table 39.

Cell Expansion Market in China, Market Size and Annual Growth Rate (2015 – 2022)....77

Table 40.

Cell Expansion Market in Japan, Market Size and Annual Growth Rate (2015 – 2022) ...78

Table 41.

Cell Expansion Market in India, Market Size and Annual Growth Rate (2015 – 2022).....78

Table 42.

– 2022)

Cell Expansion Market in Rest of Asia-Pacific, Market Size and Annual Growth Rate (2015 79

Table 43.

2022)

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By Products (2014 – 80

Table 44.

2022)

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By Applications (2014 – 82

Table 45.

2022)

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By End-users (2014 – 83

Table 46.

Cell Expansion Market in RoW, Market Snapshot ............................................................85

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Table 25.

2022)

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Table 47.

Cell Expansion Market in RoW, Market Size (US$ billion), By Regions (2014 – 2022)......86

Table 48.

2022)

Cell Expansion Market in Latin America, Market Size and Annual Growth Rate (2015 – 87

Table 49. Cell Expansion Market in Middle East and Africa, Market Size and Annual Growth Rate (2015 – 2022) ........................................................................................................................................88 Cell Expansion Market in RoW, Market Size (US$ billion), By Products (2014 – 2022) ....89

Table 51.

Cell Expansion Market in RoW, Market Size (US$ billion), By Applications (2014 – 2022) 91

Table 52.

Cell Expansion Market in RoW, Market Size (US$ billion), By End-users (2014 – 2022) ..92

Table 53.

Pen Needles Market Snapshot........................................................................................111

Table 54.

List of Acronyms..............................................................................................................112

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Table 50.

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List of Figures Research Methodology .....................................................................................................15

Figure 2.

Global Cell Expansion Market Segmentation....................................................................16

Figure 3.

Global Cell Expansion Value Chain Analysis......................................................................23

Figure 4.

U.S. Cell Expansion Regulatory Landscape........................................................................24

Figure 5.

Global Cell Expansion Market, Segment Share (%) By Products, 2016 and 2022.............25

Figure 6.

Global Cell Expansion Market Size (US$ billion), By Products, 2016 and 2022 ................27

Figure 7.

2022

Global Reagents, Media, and Sera Market, Segment Share (%) By Regions, 2016 and 27

Figure 8.

Global Reagents, Media, and Sera Market Size (US$ billion), By Regions, 2016 and 2022 28

Figure 9.

Global Disposables Market, Segment Share (%) By Regions, 2016 and 2022 ..................29

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Figure 1.

Global Disposables Market Size (US$ billion), By Regions, 2016 and 2022 ..................30

Figure 11.

Global Bioreactors Market, Segment Share (%) By Regions, 2016 and 2022 ...............30

Figure 12.

Global Bioreactors Market Size (US$ billion), By Regions, 2016 and 2022...................31

Figure 13.

Global Flow Cytometers Market, Segment Share (%) By Regions, 2016 and 2022 ......32

Figure 14.

Global Flow Cytometers Market Size (US$ billion), By Regions, 2016 and 2022..........33

Figure 15.

Global Centrifuges Market, Segment Share (%) By Regions, 2016 and 2022 ...............33

Figure 16.

Global Centrifuges Market Size (US$ billion), By Regions, 2016 and 2022...................34

Figure 17.

Global Cell Counters Market, Segment Share (%) By Regions, 2016 and 2022 ............35

Figure 18.

Global Cell Counters Market Size (US$ billion), By Regions, 2016 and 2022................36

Figure 19.

Global Other Products Market, Segment Share (%) By Regions, 2016 and 2022 .........36

Figure 20.

Global Other Products Market Size (US$ billion), By Regions, 2016 and 2022.............37

Figure 21.

Global Cell Expansion Market, Segment Share (%) By Applications, 2016 and 2022 ...38

Figure 22.

Global Cell Expansion Market Size (US$ billion), By Applications, 2016 and 2022.......39

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Figure 10.

Figure 23.

Global Cell Expansion Market for Regenerative Medicine and Stem Cell Research, Segment Share (%) By Regions, 2016 and 2022 ...................................................................................40 Figure 24.

Global Cell Expansion Market for Regenerative Medicine and Stem Cell Research, Market Size (US$ billion), By Regions, 2016 and 2022 .........................................................................41 Figure 25.

Global Cell Expansion Market for Cancer Research, Segment Share (%) By Regions, 2016 and 2022 ......................................................................................................................................42

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Figure 26.

Global Cell Expansion Market for Cancer Research, Market Size (US$ billion), By Regions, 2016 and 2022........................................................................................................................43 Figure 27.

Global Cell Expansion Market for Other Applications, Segment Share (%) By Regions, 2016 and 2022 ......................................................................................................................................44 Figure 28.

Global Cell Expansion Market for Other Applications, Market Size (US$ billion), By Regions, 2016 and 2022........................................................................................................................45 Figure 29.

Global Cell Expansion Market, Segment Share (%) By End-users, 2016 and 2022 .......46

Figure 30.

Global Cell Expansion Market Size (US$ billion), By End-users, 2016 and 2022...........47

Figure 31.

Global Cell Expansion Market for Hospitals and Cell Banks, Segment Share (%) By Regions, 2016 and 2022........................................................................................................................48 Figure 32.

Global Cell Expansion Market for Hospitals and Cell Banks, Market Size (US$ billion),

By Regions, 2016 and 2022...................................................................................................................49 Figure 33.

Global Cell Expansion Market for Biopharmaceutical Companies, Segment Share (%)

By Regions, 2016 and 2022...................................................................................................................50

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Figure 34.

Global Cell Expansion Market for Biopharmaceutical Companies, Market Size (US$ billion), By Regions, 2016 and 2022......................................................................................................51 Figure 35.

Global Cell Expansion Market for Research Institutes, Segment Share (%) By Regions, 2016 and 2022 ......................................................................................................................................52

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Figure 36.

Global Cell Expansion Market for Research Institutes, Market Size (US$ billion), By Regions, 2016 and 2022........................................................................................................................53 Global Cell Expansion Market, Segment Share (%) By Regions, 2016 and 2022 ..........54

Figure 38.

Global Cell Expansion Market Size (US$ billion), By Regions, 2016 and 2022 ..............55

Figure 39.

2022

Cell Expansion Market in North America, Segment Share (%) By Regions, 2016 and 57

Figure 40. and 2022

Cell Expansion Market in North America, Market Size (US$ billion), By Regions, 2016 58

Figure 41.

2022

Cell Expansion Market in North America, Segment Share (%) By Products, 2016 and 59

Figure 42. and 2022

Cell Expansion Market in North America, Market Size (US$ billion), By Products, 2016 61

Figure 43. and 2022

Cell Expansion Market in North America, Segment Share (%) By Applications, 2016 61

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Figure 37.

Figure 44.

Cell Expansion Market in North America, Market Size (US$ billion), By Applications, 2016 and 2022 ......................................................................................................................................62 Figure 45.

2022

Cell Expansion Market in North America, Segment Share (%) By End-users, 2016 and 63

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Cell Expansion Market in North America, Market Size (US$ billion), By End-users, 2016 64

Figure 47.

Cell Expansion Market in Europe, Segment Share (%) By Regions, 2016 and 2022 .....66

Figure 48.

Cell Expansion Market in Europe, Market Size (US$ billion), By Regions, 2016 and 2022 67

Figure 49.

Cell Expansion Market in Europe, Segment Share (%) By Products, 2016 and 2022....69

Figure 50.

2022

Cell Expansion Market in Europe, Market Size (US$ billion), By Products, 2016 and 71

Figure 51.

Cell Expansion Market in Europe, Segment Share (%) By Applications, 2016 and 2022 71

Figure 52.

2022

Cell Expansion Market in Europe, Market Size (US$ billion), By Applications, 2016 and 72

Figure 53.

Cell Expansion Market in Europe, Segment Share (%) By End-users, 2016 and 2022..73

Figure 54.

2022

Cell Expansion Market in Europe, Market Size (US$ billion), By End-users, 2016 and 74

Figure 55.

Cell Expansion Market in Asia-Pacific, Segment Share (%) By Regions, 2016 and 2022 76

Figure 56.

2022

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By Regions, 2016 and 77

Figure 57.

Cell Expansion Market in Asia-Pacific, Segment Share (%) By Products, 2016 and 2022 79

Figure 58.

2022

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By Products, 2016 and 81

Figure 59.

2022

Cell Expansion Market in Asia-Pacific, Segment Share (%) By Applications, 2016 and 81

Figure 60. and 2022

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By Applications, 2016 82

Figure 61.

Cell Expansion Market in Asia-Pacific, Segment Share (%) By End-users, 2016 and 2022 83

Figure 62. and 2022

Cell Expansion Market in Asia-Pacific, Market Size (US$ billion), By End-users, 2016 84

Figure 63.

Cell Expansion Market in RoW, Segment Share (%) By Regions, 2016 and 2022 .........86

Figure 64.

Cell Expansion Market in RoW, Market Size (US$ billion), By Regions, 2016 and 2022 87

Figure 65.

Cell Expansion Market in RoW, Segment Share (%) By Products, 2016 and 2022 .......88

Figure 66.

Cell Expansion Market in RoW, Market Size (US$ billion), By Products, 2016 and 2022 90

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Figure 46. and 2022

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Cell Expansion Market in RoW, Segment Share (%) By Applications, 2016 and 2022..90

Figure 68.

2022

Cell Expansion Market in RoW, Market Size (US$ billion), By Applications, 2016 and 91

Figure 69.

Cell Expansion Market in RoW, Segment Share (%) By End-users, 2016 and 2022......92

Figure 70.

Cell Expansion Market in RoW, Market Size (US$ billion), By End-users, 2016 and 2022 93

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Figure 67.

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1 MARKET OVERVIEW 1.1 Definitions Cell cultures are being increasingly investigated for the treatment and management of multiple diseases. Cell cultures are extensively used in the production of biologic therapeutic products. Furthermore, cell-based therapies like stem cell therapies are showing promising results in pre-clinical and clinical trial phases. Increasing research activity related to cell biology is an important driver for this market. Increasing research funding in public and private sectors too will aid market growth.

The ‘Cell Expansion Market – Global Market Size and Forecast to 2022' report includes market size and forecast estimates for the period 2014 to 2022. The scope

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of this report is instruments and consumables that are used in research and

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therapeutic applications of cell expansion. The report segments the market on the basis of products, application, end-users, and regions. The report includes market size and forecast estimates for all market segments in the study period. The report

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forecast period.

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has 2015 as the base year, 2014 as the historical year, and 2016 to 2022 as the

1.2 Research Methodology

The research methodology for market research reports at Scalar Market Research includes a combination of top-down and bottom-up research formats. Continuous market tracking, rigorous fact-checking, data-triangulation, and multiple layers of quality control ensure high quality data that can be leveraged for actionable insights.

Scalar Market Research’s research methodology starts with extensive secondary research. Important secondary sources include SEC filings, annual reports, financial reports, investor presentations, and technical & industry publications. Secondary research helps build a comprehensive map of the structure of the market. It helps identify key players in all market segments and helps build their profiles by identifying their financials, product portfolios, and growth strategies. It also identifies

14

qualitative market factors like regulatory scenario, patent estates, and market developments.

Figure 1. Research Methodology

Top-down Global Market Size

Global Market Size

Market-specific Revenues of Key Players

Segment-specific Market Size

Regional Total Revenues of Key Players

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Market Size

Bottom-up

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Source: Scalar Market Research Analysis

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A bottom-up market sizing format is used to arrive at the top-line market size.

Revenues of key market players used to arrive at the market-specific revenues of

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each key market player. A process of inward bracketing is used to arrive at the market-specific revenues for each key market player. The market specific revenues are combined to arrive at the top-line global market size. Segment-specific and regional market sizes are estimated through top-down market sizing.

Data synthesis and triangulation techniques are used to develop the market model.

The model represents current consensus market opinion. The market estimates from the model are used to generate reports that include qualitative and quantitative insights about the market.

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1.3 Market Segmentation Figure 2. Global Cell Expansion Market Segmentation Global Cell Expansion Market By Applications

By End-users

By Regions

Reagents, Media, and Sera

Regenerative Medicine and Stem Cell Research

Hospitals and Cell Banks

Disposables

Cancer Research

Biopharmaceuti cal Companies

U.S.

Germany

China

Latin America

Bioreactors

Other Applications

Research Institutes

Rest of North America

U.K.

Japan

Middle East and Africa

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By Products

India

Rest of Europe

Rest of AsiaPacific

North America

Flow Cytometers

Europe

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France

Centrifuges

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Cell Counters

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Other Products Source: Scalar Market Research Analysis

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Asia-Pacific

RoW

2 EXECUTIVE SUMMARY Table 1.

Global Cell Expansion Market Snapshot Market Size (US$ billion)

Global Cell Expansion Market

2016 7.96

Total

2022 18.74

Reagents, Media, and Sera Disposables Bioreactors Flow Cytometers

Cell Counters

Cancer Research

Hospitals and Cell Banks Biopharmaceutical Companies Research Institutes North America Europe

Regions

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Other Applications

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Regenerative Medicine and Stem Cell Research

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Other Products

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End-users

Applications

Products

Centrifuges

Asia-Pacific RoW

Source: Scalar Market Research Analysis

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CAGR% (2016 – 2022) 15.3

3 MARKET DYNAMICS 3.1

Drivers

Table 2.

Global Cell Expansion Market Drivers 2014-16

Drivers

2017- 19

Increasing investments of stem cell therapy Stem cell therapy is set to revolutionize the field of medical treatments. However, huge funding i s required to be invested to overcome the cell therapy manufacturing challenges and come up with innovative products. Large number of organizations and governments across the globe are hugely investing in stem cell research.

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In the U.S, in 2016, the National Institutes of Health (NIH) invested around $1.495 billion into stem cell research projects. In 2016, the Canadian government provided funds over $20 million in order to establish a new facility for the Centre for the Commercialization of Regenerative Medicine.

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Source: Scalar Market Research Analysis Note:

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● Very High Impact, ◕ High Impact, ◑ Medium Impact, ◔ Low Impact

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◕

2020-22

3.2

Restraints

Table 3.

Global Cell Expansion Market Restraints Restraints

2014-16

High costs associated with cell based therapies

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● Very High Impact, ◕ High Impact, ◑ Medium Impact, ◔ Low Impact

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Note:

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Source: Scalar Market Research Analysis

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2020-22

●

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For instance, treatment with Prochymal which is a stem celltherapy to relieve rejection of bone-marrow transplants in children, is expected to cost as high as $200,000. The cell based vaccine, Provenge for the treatment of prostrate cancer was priced at $93,000 that extended patients' lives by an average of four months.

2017- 19

◑

4 INDUSTRY ANALYSIS 4.1 Value Chain Analysis Figure 3. Global Cell Expansion Value Chain Analysis

Hospitals Raw Material & Sub-component Suppliers

OEMs & System Integrators

Cell Expansion Manufacturers

End-users

Research Organizations

E

High level of Integration

SA

M

PL

Source: Scalar Market Research Analysis

23

Clinics

5 CELL EXPANSION MARKET, BY PRODUCTS The global cell expansion market is expected to be valued at US$XX billion in 2016.

This market is expected to grow at a CAGR of XX% in the forecast period and reach US$ XX billion by 2022. The product segments in this market are reagents, media, and sera, disposables, bioreactors, flow cytometers, centrifuges, cell counters, and other products. Reagents, media, and sera are the largest product segment. It is expected to have a XX% share of the global cell expansion market in 2016. On the other hand, the flow cytometers segment is expected to grow at the highest rate in the forecast period. The share of this market segment is expected to grow from XX% in 2016 to XX% in the 2022.

E

5.1 Segment Share

2016

2022

7.6%

5.7%

5.9%

Reagents, Media, and Sera

6.7%

10.3%

Disposables

30.6%

M

31.7%

SA

9.9%

13.2%

PL

Figure 5. Global Cell Expansion Market, Segment Share (%) By Products, 2016 and 2022

15.8%

Flow Cytometers Centrifuges

14.9% 14.4%

15.9%

17.3%

Source: Scalar Market Research Analysis

25

Bioreactors

Cell Counters Other Products

5.2 Global Cell Expansion Market, By Products Table 4.

Global Cell Expansion Market Size (US$ billion), By Products (2014 – 2022)

Products

2014

2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

Reagents, Media, and Sera Disposables Bioreactors Flow Cytometers Centrifuges Cell Counters

E

Other Products Total

PL

Source: Scalar Market Research Analysis

Reagents, media, and sera is the largest product segment of the global cell

M

expansion market. This segment is expected be valued at US$ XX billion in 2016.

On the other hand, flow cytometers is expected to be the fastest-growing product

SA

segment in the forecast period. This segment is expected to grow at a CAGR of XX% between 2016 and 2022.

26

2016

5.73

1.05

0.79

1.26 0.60

E

1.08 0.47

Other Products

1.92

Cell Counters

1.26

Centrifuges

Disposables

1.26

2.80

Flow Cytometers

2.52

2022

3.25

Bioreactors

2.70

Reagents, Media, an d Sera

Market Size (US$ billion)

Figure 6. Global Cell Expansion Market Size (US$ billion), By Products, 2016 and 2022

5.2.1 Reagents, Media, and Sera

PL

Source: Scalar Market Research Analysis

SA

2016

M

Figure 7. Global Reagents, Media, and Sera Market, Segment Share (%) By Regions, 2016 and 2022

12.6%

2022 North America 13.8% 30.4%

34.2%

20.8%

Europe

25.3% Asia-Pacific

30.4%

32.4%

Source: Scalar Market Research Analysis

27

RoW

Table 5.

Global Reagents, Media, and Sera Market Size (US$ billion), By Regions (2014 – 2022)

Regions

2014

2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

North America Europe Asia-Pacific Rest of the World Total Source: Scalar Market Research Analysis

E

North America is the largest regional segment of the global reagents, media, and sera market. This segment is expected be valued at US$ XX billion in 2016. On the

PL

other hand, Asia-Pacific is expected to be the fastest-growing regional segment in the forecast period. This segment is expected to grow at a CAGR of XX% between

M

2016 and 2022.

SA

Figure 8. Global Reagents, Media, and Sera Market Size (US$ billion), By Regions, 2016 and 2022

Market Size (US$ billion)

1.74

0.86

1.74 1.45

0.82

0.79 0.52 0.32

North America

Europe

Asia-Pacific 2016

Source: Scalar Market Research Analysis

28

2022

RoW

6 CELL EXPANSION MARKET, BY APPLICATIONS The global cell expansion market is expected to be valued at US$ XX billion in 2016.

This market is expected to grow at a CAGR of XX% in the forecast period and reach US$ XX billion by 2022. The application segments in this market are regenerative medicine and stem cell research, cancer research, and other applications.

Regenerative medicine and stem cell research is the largest application segment. It is expected to have a XX% share of the global cell expansion market in 2016. This segment is also expected to grow at the highest rate in the forecast period. The share of this market segment is expected to grow to XX% in the 2022.

E

6.1 Segment Share

PL

Figure 21. Global Cell Expansion Market, Segment Share (%) By Applications, 2016 and 2022 2016

2022

Regenerative Medicine and Stem Cell Research

23.2%

M

25.0%

SA

41.9%

44.7%

32.1%

33.1%

Source: Scalar Market Research Analysis

38

Cancer Research

Other Applications

6.2 Global Cell Expansion Market, By Applications Table 12. Global Cell Expansion Market Size (US$ billion), By Applications (2014 – 2022) Applications

2014

2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

Regenerative Medicine and Stem Cell Research Cancer Research Other Applications Total Source: Scalar Market Research Analysis

E

Regenerative medicine and stem cell research is the largest application segment of

PL

the global cell expansion market. This segment is expected be valued at US$ XX billion in 2016. This segment is also expected to be the fastest-growing application segment in the forecast period. This segment is expected to grow at a CAGR of

M

XX% between 2016 and 2022.

SA

Figure 22. Global Cell Expansion Market Size (US$ billion), By Applications, 2016 and 2022

Market Size (US$ billion)

8.37

6.02 4.35

3.34

Regenerative Medicine and Stem Cell Research

2.63

1.99

Cancer Research

2016 Source: Scalar Market Research Analysis

39

2022

Other Applications

6.2.1 Regenerative Medicine and Stem Cell Research Figure 23. Global Cell Expansion Market for Regenerative Medicine and Stem Cell Research, Segment Share (%) By Regions, 2016 and 2022 2016

2022 North America

13.1%

14.4% 28.9%

32.7%

Europe

21.3% 26.1%

Asia-Pacific

RoW

30.6%

32.9%

E

Source: Scalar Market Research Analysis

Regions

2014

2015

2016

Europe

Total

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

SA

Asia-Pacific Rest of the World

2017

M

North America

PL

Table 13. Global Cell Expansion Market for Regenerative Medicine and Stem Cell Research, Market Size (US$ billion), By Regions (2014 – 2022)

Source: Scalar Market Research Analysis

North America is the largest regional segment of the global cell expansion market for regenerative medicine and stem cell research. This segment is expected be valued at US$ XX billion in 2016. On the other hand, Asia-Pacific is expected to be the fastest-growing regional segment in the forecast period. This segment is expected to grow at a CAGR of XX% between 2016 and 2022.

40

Figure 24. Global Cell Expansion Market for Regenerative Medicine and Stem Cell Research, Market Size (US$ billion), By Regions, 2016 and 2022 2.56

Market Size (US$ billion)

2.42

1.09

2.19

1.21

1.10 0.71 0.44

North America

Europe

Asia-Pacific 2022

E

2016

SA

M

PL

Source: Scalar Market Research Analysis

41

RoW

7 CELL EXPANSION MARKET, BY END-USERS The global cell expansion market is expected to be valued at US$ XX billion in 2016.

This market is expected to grow at a CAGR of XX% in the forecast period and reach US$ XX billion by 2022. The end-user segments in this market are hospitals and cell banks, biopharmaceutical companies, and research institutes. Hospitals and cell banks is the largest end-user segment. It is expected to have a XX% share of the global cell expansion market in 2016. On the other hand, the biopharmaceutical companies segment is expected to grow at the highest rate in the forecast period.

The share of this market segment is expected to grow from XX% to XX% in the

E

2022.

7.1 Segment Share

PL

Figure 29. Global Cell Expansion Market, Segment Share (%) By End-users, 2016 and 2022 2022

M

2016

28.9%

Hospitals and Cell Banks

28.1% 38.0%

SA

38.5%

Biopharmaceutical Companies

Research Institutes 33.9%

32.6%

Source: Scalar Market Research Analysis

46

7.2 Global Cell Expansion Market, By End-users Table 16. Global Cell Expansion Market Size (US$ billion), By End-users (2014 – 2022) End-users

2014

2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

Hospitals and Cell Banks Biopharmaceutical Companies Research Institutes Total Source: Scalar Market Research Analysis

E

Hospitals and cell banks are the largest end-user segment of the global cell

PL

expansion market. This segment is expected be valued at US$ XX billion in 2016.

This segment is also expected to be the fastest-growing end-user segment in the forecast period. This segment is expected to grow at a CAGR of XX% between 2016

M

and 2022.

SA

Figure 30. Global Cell Expansion Market Size (US$ billion), By End-users, 2016 and 2022

Market Size (US$ billion)

7.11

3.06

Hospitals and Cell Banks

6.35 5.27

2.59

2.30

Biopharmaceutical Companies 2016

Source: Scalar Market Research Analysis

47

2022

Research Institutes

7.2.1 Hospitals and Cell Banks Figure 31. Global Cell Expansion Market for Hospitals and Cell Banks, Segment Share (%) By Regions, 2016 and 2022 2016

2022

10.2%

North America

10.7%

36.9%

17.4%

34.4% 20.1%

Europe

Asia-Pacific

35.4%

RoW

34.8%

E

Source: Scalar Market Research Analysis

Regions

2014

2015

2016

Europe

Total

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

SA

Asia-Pacific Rest of the World

2017

M

North America

PL

Table 17. Global Cell Expansion Market for Hospitals and Cell Banks, Market Size (US$ billion), By Regions (2014 – 2022)

Source: Scalar Market Research Analysis

North America is the largest regional segment of the global cell expansion market for hospitals and cell banks. This segment is expected be valued at US$ XX billion in 2016. On the other hand, Asia-Pacific is expected to be the fastest-growing regional segment in the forecast period. This segment is expected to grow at a CAGR of XX% between 2016 and 2022.

48

Figure 32. Global Cell Expansion Market for Hospitals and Cell Banks, Market Size (US$ billion), By Regions, 2016 and 2022

2.48

Market Size (US$ billion)

2.45

1.43 1.13

1.08 0.53

North America

Europe

Asia-Pacific 2022

E

2016

SA

M

PL

Source: Scalar Market Research Analysis

49

0.76 0.31

RoW

8 CELL EXPANSION MARKET, BY REGIONS The global cell expansion market is segmented into regional segments of North America, Europe, Asia-Pacific, and Rest of the World. North America is expected to be the largest regional segment in 2016. This segment is expected to have a share of XX% in 2016. On the other hand, Asia-Pacific is expected to be the fastestgrowing regional segment in the forecast period. The share of this segment is expected to grow from XX% in 2016 to XX% in 2022.

North America is further sub-segmented into U.S. and Rest of North America.

Europe is further sub-segmented into Germany, U.K., France, and Rest of Europe.

Asia-Pacific is further sub-segmented into China, Japan, India, and Rest of Asia-

E

Pacific. Rest of the World is further sub-segmented into Latin America and Middle

PL

East and Africa.

8.1 Segment Share

SA

2016

M

Figure 37. Global Cell Expansion Market, Segment Share (%) By Regions, 2016 and 2022

13.8%

2022 North America 15.1% 28.6%

32.6%

23.1%

Europe

Asia-Pacific

28.0%

28.3%

30.5%

Source: Scalar Market Research Analysis

54

RoW

8.2 Global Cell Expansion Market, By Regions Table 20. Global Cell Expansion Market Size (US$ billion), By Regions (2014 – 2022) Regions

2014

2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

North America Europe Asia-Pacific Rest of the World Total Source: Scalar Market Research Analysis

E

North America is the largest regional segment of the global cell expansion market.

PL

This segment is expected be valued at US$ XX billion in 2016. On the other hand, Asia-Pacific is expected to be the fastest-growing regional segment in the forecast period. This segment is expected to grow at a CAGR of XX% between 2016 and

M

2022.

SA

Figure 38. Global Cell Expansion Market Size (US$ billion), By Regions, 2016 and 2022

Market Size (US$ billion)

5.36

2.60

5.30

5.25

2.83

2.43 1.84 1.10

North America

Europe

Asia-Pacific 2016

Source: Scalar Market Research Analysis

55

2022

RoW

8.3 North America The cell expansion market in North America is sub-segmented into U.S. and Rest of North America. U.S. is expected to be the largest regional segment North America in 2016. This segment is expected to have an XX% share of the market in 2016. On the other hand, Rest of North America is expected to be the fastest-growing regional segment in North America in the forecast period. The share of this segment is expected to grow from XX% in 2016 to XX% in 2022.

Table 21. Cell Expansion Market in North America, Market Snapshot

Total

Market Size (US$ billion) 2016 2.60

PL

Reagents, Media, and Sera Disposables

Flow Cytometers

Regions

End-users

Cell Counters

SA

Applications

Products

Centrifuges

M

Bioreactors

Other Products

Regenerative Medicine and Stem Cell Research Cancer Research

Other Applications Hospitals and Cell Banks Biopharmaceutical Companies Research Institutes U.S. Rest of North America

Source: Scalar Market Research Analysis

56

2022 5.36

E

Cell Expansion Market in North America

CAGR% (2016 – 2022) 12.9

8.3.1 Cell Expansion Market in North America, By Regions Figure 39. Cell Expansion Market in North America, Segment Share (%) By Regions, 2016 and 2022 2016

2022

18.9%

20.7%

U.S.

Rest of North America

79.3%

81.1%

E

Source: Scalar Market Research Analysis

2014

2015

Total

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

SA

U.S. Rest of North America

2016

M

Regions

PL

Table 22. Cell Expansion Market in North America, Market Size (US$ billion), By Regions (2014 – 2022)

Source: Scalar Market Research Analysis

U.S. is the largest regional segment of the cell expansion market in North America.

This segment is expected be valued at US$ XX billion in 2016. On the other hand, Rest of North America is expected to be the fastest-growing regional segment in North America in the forecast period. This segment is expected to grow at a CAGR of XX% between 2016 and 2022.

57

Figure 40. Cell Expansion Market in North America, Market Size (US$ billion), By Regions, 2016 and 2022

Market Size (US$ billion)

4.25

2.11 1.11 0.49

U.S.

Rest of North America 2022

E

2016

PL

Source: Scalar Market Research Analysis

Market Size (US$ billion) Annual Growth Rate (%)

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

SA

2015

M

8.3.1.1 U.S. Table 23. Cell Expansion Market in U.S., Market Size and Annual Growth Rate (2015 – 2022)

Source: Scalar Market Research Analysis

The cell expansion market in U.S. is expected to grow from US$ XX billion in 2016 to US$ XX billion in 2022 at a CAGR of 12.4% between these two years. The annual growth rates for this market segment are expected to vary between XX% and XX% in this period.

58

8.3.1.2 Rest of North America Table 24. Cell Expansion Market in Rest of North America, Market Size and Annual Growth Rate (2015 – 2022) 2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

Market Size (US$ billion) Annual Growth Rate (%) Source: Scalar Market Research Analysis

The cell expansion market in Rest of North America is expected to grow from US$ XX billion in 2016 to US$ XX billion in 2022 at a CAGR of XX% between these two years. The annual growth rates for this market segment are expected to vary

PL

E

between XX% and XX% in this period.

8.3.2 Cell Expansion Market in North America, By Products

2016

10.0%

13.3%

SA

7.9% 5.2%

M

Figure 41. Cell Expansion Market in North America, Segment Share (%) By Products, 2016 and 2022

33.3%

2022 4.9%

Reagents, Media, and Sera

7.1%

Disposables

32.5%

10.3%

Bioreactors Flow Cytometers Centrifuges

14.9%

Cell Counters

14.3%

16.1%

15.5%

Source: Scalar Market Research Analysis

59

14.8% Other Products

Table 25. Cell Expansion Market in North America, Market Size (US$ billion), By Products (2014 – 2022) Products

2014

2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

Reagents, Media, and Sera Disposables Bioreactors Flow Cytometers Centrifuges Cell Counters Other Products

E

Total

PL

Source: Scalar Market Research Analysis

Reagents, media, and sera are the largest product segment of the cell expansion

M

market in North America. This segment is expected be valued at US$ XX billion in 2016. On the other hand, flow cytometers is expected to be the fastest-growing

SA

product segment in the forecast period. This segment is expected to grow at a CAGR of XX% between 2016 and 2022.

60

Figure 42. Cell Expansion Market in North America, Market Size (US$ billion), By Products, 2016 and 2022 2016

0.83

0.80 0.55 0.26

0.26 0.14

0.38 0.21

E

Other Products

0.34

Cell Counters

0.37

Centrifuges

Disposables

0.42

2022

Flow Cytometers

0.79

Bioreactors

0.86

Reagents, Media, an d Sera

Market Size (US$ billion)

1.74

PL

Source: Scalar Market Research Analysis

8.3.3 Cell Expansion Market in North America, By Applications

26.7%

SA

2016

M

Figure 43. Cell Expansion Market in North America, Segment Share (%) By Applications, 2016 and 2022 2022 Regenerative Medicine and Stem Cell Research

24.9%

42.1%

45.1%

Cancer Research

Other Applications 30.0%

31.3%

Source: Scalar Market Research Analysis

61

Table 26. Cell Expansion Market in North America, Market Size (US$ billion), By Applications (2014 – 2022) Applications

2014

2015

2016

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

Regenerative Medicine and Stem Cell Research Cancer Research Other Applications Total Source: Scalar Market Research Analysis

Regenerative medicine and stem cell research is the largest application segment of

E

the cell expansion market in North America. This segment is expected be valued at

PL

US$ XX billion in 2016. This segment is also expected to be the fastest-growing application segment in the forecast period. It is expected to grow at a CAGR of XX%

M

between 2016 and 2022.

SA

Market Size (US$ billion)

Figure 44. Cell Expansion Market in North America, Market Size (US$ billion), By Applications, 2016 and 2022

2.42

1.61 1.33

1.09 0.81

Regenerative Medicine and Stem Cell Research

0.69

Cancer Research

2016 Source: Scalar Market Research Analysis

62

2022

Other Applications

8.3.4 Cell Expansion Market in North America, By End-users Figure 45. Cell Expansion Market in North America, Segment Share (%) By End-users, 2016 and 2022 2016

2022 Hospitals and Cell Banks 26.0%

27.8%

43.6%

45.6%

Research Institutes

28.4%

28.6%

E

Source: Scalar Market Research Analysis

Biopharmaceutical Companies

2014

2015

Research Institutes Total

2017

2018

2019

2020

2021

2022

CAGR% (2016 – 2022)

SA

Hospitals and Cell Banks Biopharmaceutical Companies

2016

M

End-users

PL

Table 27. Cell Expansion Market in North America, Market Size (US$ billion), By Endusers (2014 – 2022)

Source: Scalar Market Research Analysis

Hospitals and cell banks are the largest end-user segment of the cell expansion market in North America. This segment is expected be valued at US$ XX billion in 2016. This segment is also expected to be the fastest-growing end-user segment in the forecast period. It is expected to grow at a CAGR of XX% between 2016 and 2022.

63

Market Size (US$ billion)

Figure 46. Cell Expansion Market in North America, Market Size (US$ billion), By Endusers, 2016 and 2022

2.45

1.52

1.40

1.13 0.74

Hospitals and Cell Banks

0.72

Biopharmaceutical Companies 2022

E

2016

Research Institutes

SA

M

PL

Source: Scalar Market Research Analysis

64

11 APPENDIX 11.1 Acronyms Table 54. List of Acronyms Acronym

Expansion

RoW

Rest of the World

CAGR

Compound Annual Growth Rate

W.H.O.

World Health Organization

Stem Cell Therapy Market, by Treatments (Allogeneic Stem Cell Therapy,

PL



E

11.2 Related Reports

Autologous Stem Cell Therapy), Applications (Oncology, Eye Diseases, Central Nervous System Diseases, Musculoskeletal Diseases, Wound & Injuries, Metabolic

M

Disorders, Cardiovascular Disorders, Immune System Disorders), End-users (Hospitals, Ambulatory Surgical Centers) - Global Revenue, Trends, Growth, Share,



SA

Size and Forecast to 2022

Biologics Market, by Products (Vaccines, Human Cells and Tissues, Gene Therapies, Xenotransplantation Products, Blood & Blood Product, Proteins & Allergenic Extracts ), Source Materials (Avian Cell Culture, Bacteria, Transgenic, Yeast, Insect Cell Culture & Humans ) and Applications (Cancer, Diabetes, Rheumatoid Arthritis, and Anemia ) - Global Revenue, Trends, Growth, Share, Size and Forecast to 2022

112