Oxidative Stress r esearch Centre (OS r C)

Prof Jeanine Marnewick

The OSRC contributes to existing knowledge regarding the role of oxidative stress in health and disease development through high-quality research. These research findings and knowledge are disseminated to the general public in order to improve the health status of the South African population. The centre also houses the Analytical Testing Laboratory, serving the dual purpose of providing a testing service to industry and other institutes, as well as training postgraduate students.

2014 brought about exciting new opportunities for the OSRC, one being the creation of the Institute of Biomedical and Microbial Biotechnology (IBMB) at CPUT by the office of the DVC: RTIP. Together with IBMB, we will enhance research capacity and capabilities in order to ensure a multidisciplinary approach to address research questions. This year, the centre welcomed a new senior scientist, Dr Liana van der Westhuizen, to drive a new research initiative investigating dietary compounds showing potential in disease prevention as biomarkers of exposure, efficacy and bioavailability, as well as their drug interactions. We also welcomed Dr Dirk Bester as the new research leader of the Experimental Biology initiative in the centre. We wish them every success.

As always, 2014 has been a very productive year, with outputs concentrated around publications and invited talks. Prof Oguntibeju, leader of the Nutrition and Chronic Disease Research Group, and his colleagues presented at two international and one national conference and published seven articles and seven book chapters. Dr Van der Westhuizen received the best paper of the year award from the editors of the World Mycotoxin Journal for a paper titled Fumonisin biomarkers in maize eaters and implications for human disease. Seven publications, one book chapter and a number of conference presentations emanated from the Medicinal Plant Research Group.

Various role players in industry and the higher education sector showed keen interest in our research involving rooibos and its health benefits. In this regard, Prof Marnewick was the invited guest speaker at the annual Afriplex Technical Symposium; the Innovation Symposium (ATS in association with the TIA, Industrial Development Corporation and CPUT); the South African Association for Food Science and Technology (SAAFoST) Cape Branch Symposium; the Cell Biology Symposium (Anatomical Society of Southern Africa); and at the lecture series presented by the Royal Society of South Africa and the Academy of Science of South Africa. A concerted effort was made to disseminate our research to the general public: Prof Marnewick featured in the DRUSSA Digest in October regarding her successful research uptake strategy at CPUT, while she also presented at the Hermanus Culture Society and at the Worcester Herbal Club. She attended SARIMA’s Get Strategic with Science

One of our neighbouring institutes (SU’s Department of Medical Physiology and Department of Physiology,) invited Dr Bester to present on the effects of dietary Garcinia kola supplementation on myocardial ischaemia/reperfusion and the role of inflammation in the isolated perfused rat heart model. Research collaborations with these departments were subsequently established. A number of our researchers also collaborate globally, including with the University of Kaposvar.

All in all, it was a good year for the OSRC, and we aim to build on that in 2015.

books/chapters

Aboua YG, Manirafasha C, Mosito RB, Van der Linde M & Du Plessis S

Potential of phytotherapeutic treatment of erectile dysfunction

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 279-295, ISBN 978-953-51-1215-0

Adedapa AA, Ofuegbe S & Oguntibeju OO

The antidiabetic activities of the aqueous leaf extract of phyllanthus amarus in some laboratory animals

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 115-137, ISBN 978-953-51-1215-0

Akinmoladun AC, Farombi EO & Oguntibeju OO

Antidiabetic botanicals and their potential benefit in the management of diabetes mellitus

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 139-164, ISBN 978-953-51-1215-0

Alinde OBL, Esterhuyse AJ & Oguntibeju OO

Potential role of Parkia biglobosa in the management and treatment of cardiovascular diseases

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 349-369, ISBN 978-953-51-1215-0

Arise RO, Aderounmu AL & Oguntibeju OO

Lipid profile, antidiabetic and antioxidant activity of Acacia ataxacantha bark exctract in Streptozotocininduced diabetic rats

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 3-23, ISBN 978-953-51-1215-0

Ayepola OR, Brooks NL & Oguntibeju OO

Oxidative stress and diabetic complications: The role of antioxidant vitamins and flavonoids

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 25-58, ISBN 978-953-51-1215-0

Esterhuyse AJ, Farombi EO, Oguntibeju OO, Oyagbemi AA & Salihu MM

Some selected medicinal plants with antidiabetic potentials

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 95-113, ISBN 978-953-51-1215-0

Marnewick JL, Venter I, Rautenbach F, Neethling H & Kotze M

Rooibos: Effect on iron status in South African adults at risk for coronary heart disease

Juliani HR, Simon JE & Ho C-T (eds): African Natural Plant Products Volume II: New Discoveries and Challenges in Chemistry and Quality

New York: Oxford University Press, 2013, pp 103-114, ISBN 978-084-12-2804-7

Obizoba IC, Oguntibeju OO & Udenta EA Anti-diabetic effects of Nigerian indegenous plant foods/diets

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 59-93, ISBN 978-953-51-1215-0

Oyenihi AB, Brooks NL, Oguntibeju OO & Aboua YG

Antioxidant-rich natural products and diabetes mellitus

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 317-345, ISBN 978-953-51-1215-0

Pantsi WG, Bester DJ, Esterhuyse AJ & Aboua YG

Dietary antioxidant properties of vegetable oils and nuts – The race against cardiovascular disease progression

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 209-238, ISBN 978-953-51-1215-0

Skosana B, Aboua YG & Du Plessis S Buchu – The multi-purpose ethnomedicinally important species and its benefits in the reproductive system

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 297-316, ISBN 978-953-51-1215-0

Valente C, Aboua YG & Du Plessis S Garlic and its effects on health with special reference to the reproductive system

Oguntibeju OO (ed): Antioxidant-Antidiabetic Agents and Human Health

Croatia: InTech, 2014, pp 259-277, ISBN 978-953-51-1215-0

Conference papers

Ayeleso AO, Oguntibeju OO & Brooks NL

Impact of co-administration of red palm oil (Elaeis guineensis) and rooibos (Aspalathus linearis) on glycaemic parameters, key glycolytic enzymes and liver function in diabetic rats, 2nd International Conference of the African Society for Lab Medicine, Cape Town, 30 November-4 December 2014

Davies SEH, West S, Taliep S, Rautenbanch F & Marnewick J

Anti-oxidants and exercise performance: Preliminary findings regarding rooibos (Aspalathus linearis), Zing Conference on Oxidative Stress Parador de Orospesa, Madrid, 3-6 October 2014

Davison GM, Esterhuyse AJ & Aggett H

Haematology education in Africa, Inaugural Indian Ocean Rim Laboratory Haematology Congress, Perth, 16-17 October 2014

Engel-Hills P

The contribution of professional education to the disaster recovery process, FMU-IAEA International Academic Conference – Radiation, Health, and Population: The Multiple Dimensions of PostFukushima Disaster Recovery, Fukushima, Japan, July 2014

Engel-Hills P, Rip A & Winberg C

Ethics “upfront”: Generating an organizational framework for a new university of technology, 2014 IEEE International Symposium on Ethics in Engineering, Science, and Technology, Ethics’2014, Chicago, IL, 23-24 May 2014

Oguntibeju OO, Ayepola O & Brooks NL

Antioxidant, anti-inflammatory and anti-lipidaemic effects of bitter kola seeds-derived biflavonoid complex (kolaviron) in the blood of diabetic rats, European Congress of Pathology-Understanding Disease, London, 29 August-3 September 2014

Olabiyi FA, Olatunji OI, Makinwa TT & Oguntibeju OO

Palm oil and groundnut oil supplementation effects on hyperglycaemic and antioxidant status of diabetic rats, 50th Annual Conference of the Association of Medical Laboratory Scientists of Nigeria, Akure, Nigeria, 2-7 November 2014

Marnewick JL

Dietary flavonoids, more than just antioxidants, South African Association for Food Science and Technology Symposium, Cape Town, 23 July 2014

Marnewick JL

Dietary polyphenols and health: Do we need them? Afriplex Integrated Pharmacy Technical Symposium, Stellenbosch, 2 April 2014

Marnewick JL

Rooibos: Food for health applications, Innovation Symposium, Cape Town, 17 September 2014

Marnewick JL

Rooibos and Honeybush: Protection against the African sun, Cell Biology Symposium, Stellenbosch, 13 April 2014

Shephard GS, Burger H-M, Gambacorta L, Gong YY, Krska R, Rheeder JP, Solfrizzo M, Srey C, Sulyok M, Visconti A, Warth B & Van der Westhuizen L

Measuring mycotoxin exposure in a South African rural community, International Mycotoxin Conference, Beijing, 19-23 May 2014

Sibanda L, Engel-Hills P & Davidson F Plain skull and plain lumbar spine diagnostic radiology requests in Zimbabwe’s public hospital complex: Completeness, accuracy and justification, Government of Zimbabwe, Research and Intellectual Expo, Science, Engineering and Technology (RIE-SET) 2014, Harare, 3-6 September 2014

Conference posters

Esau C, Khalil D & Dunn A

Prevention and management of occupational injuries at selected higher education instructions in the Western Cape, South Africa, CPUT Research Day, 27 November 2014

Garba I, Davidson F & Engel-Hills P

Local diagnostic reference level for brain computed tomography scan in Nigeria, International Conference on Radiation Protection in Medicine, Varna, Bulgaria, 30 May-2 June 2014

Popoola OK, Marnewick JL, Rautenbach F, Ameer F & Hussein A

Inhibition of oxidative stress and tyrosinase in vitro by South African Helichrysum teretifolium constituents PACN Congress 2014 – Biodiversity and Global Challenges: A Chemical Sciences Approach, Addis Ababa, 30 November-2 December 2014

Pretorius M, Khalil DD & Dunn A

Knowledge and practices of occupational health nurse practitioners in the management of diabetes mellitus in South Africa, CPUT Research Day, 27 November 2014

Pretorius M, Khalil D & Dunn A

Lack of knowledge and gaps in practices of occupational health nurse practitioners in management of diabetes mellitus in South Africa, CPUT Research Day 2014, 27 November 2014

Rheeder JP, Imri G, Shephard GS & Van der Westhuizen L

Fumonisin levels and Fusarium species in maize collected from rural areas in the Eastern Cape, South Africa, CPUT Research Day 2014, 27 November 2014

Van der Westhuizen L, Shephard GS, Burger HM, Rheeder JP, Gelderblom WCA, Wild CP & Gong YY

Culturally acceptable intervention method reduced fumonisin exposure in maize subsistence farmers of the Eastern Cape, CPUT Research Day, 27 November 2014

Vergotine Z, Kengne AP, Pillay TS, Erasmus RT & Matsha TE

Indices of insulin resistance and markers of sub-clinical cardiovascular disease in mixed-ancestry South Africans, International Federation of Clinical Chemistry (IFCC) and Laboratory Medicine, World Lab Congress, Istanbul, 22-26 June 2014

Vergotine Z, Yako Y, Kengne AP, Erasmus RT & Matsha TE

The potential associations of rare peroxisome proliferator-activated receptor gamma (PPARG) mutations with insulin resistance and diabetes risk in a South African population, UNIPATH and Laboratory Medicine in the Era of P4 Medicine, Pretoria, 19-21 September 2014

journal articles (DHET subsidised)

Ajuwon OR, Oguntibeju OO & Marnewick JL

Amelioration of lipopolysaccharide-induced liver injury by aqueous rooibos (Aspalathus linearis) extract via inhibition of proinflammatory cytokines and oxidative stress

BMC Complementary and Alternative Medicine, 14(392):1-12, 2014

Ayeleso AO, Oguntibeju OO, Aboua YG & Brooks NL

Effects of red palm oil and rooibos on sperm motility parameters in streptozotocin-induced diabetic rats

African Journal of Traditional Complementary and Alternative Medicines, 11(5):8-15, 2014

Ayeleso AO, Oguntibeju OO & Brooks NL In vitro study on the antioxidant potentials of the leaves and fruits of Nauclea latifolia

Scientific World Journal, 2014(Article ID 437081):1-8, 2014

Ayepola OR, Brooks NL & Oguntibeju OO

Kolaviron improved resistance to oxidative stress and inflammation in the blood (erythrocyte, serum and plasma) of streptozotocin-induced diabetic rats

Scientific World Journal, 2014(Article ID 921080):1-8, 2014

Ayepola OR, Cerf M, Brooks NL & Oguntibeju OO

Kolaviron, a biflavonoid complex of Garcinia kola seeds modulates apoptosis by suppressing oxidative stress and inflammation in diabetes-induced nephrotoxic rats

Phytomedicine, 21:1785-1793, 2014

Bester BH & Sobuwa S

Utilisation of prehospital intravenous access

SAMJ South African Medical Journal, 104(9):615-618, 2014

Canda BD, Oguntibeju OO & Marnewick JL

Effects of consumption of rooibos (Aspalathus linearis) and a rooibos-derived commercial supplement on hepatic tissue injury by tertbutyl hydroperoxide in Wistar rats

Oxidative Medicine and Cellular Longevity, 2014 (Article ID 716332):1-9, 2014

Dobrowsky PH, Van Deventer A, De Kwaadsteniet M, Ndlovu T, Khan S, Cloete TE & Khan W

Prevalence of virulence genes associated with pathogenic Escherichia coli strains isolated from domestically harvested rainwater during low- and high-rainfall periods

Applied and Environmental Microbiology, 80(5):1633-1638, 2014

Freemantle CS, Sacks N, Topic M & PinedaVargas CA

Impurity characterization of zinc-recycled WC-6 wt% Co cemented carbides

International Journal of Refractory Metals & Hard Materials, 44:94-102, 2014

Gachago D, Ivala EN, Barnes VE, FelixMinnaar JV, Morkel J & Vajat N

Towards the development of digital storytelling practices for use in resource-poor environments, across disciplines and with students from diverse backgrounds

South African Journal of Higher Education, 28(3):961-982, 2014

Garraway JW, Hugo CV & De Waal B

Futures studies and scenarios of degrees in universities of technology

Progressio, 36(1):19-33, 2014

Gihwala D, Mars JA & Pineda-Vargas CA

Application of particle-induced X-ray emission, backscattering spectrometry and scanning electron microscopy in the evaluation of orthodontic materials

Journal of Radioanalytical and Nuclear Chemistry, 279:423-429, 2013

Grant KA, Apffelstaedt JP, Wright C, Myburgh E, Pienaar R, De Klerk M & Kotze MJ

MammaPrint Pre-screen Algorithm (MPA) reduces chemotherapy in patients with earlystage breast cancer

SAMJ South African Medical Journal, 103(8):522-526, 2013

Guesmia A, Ammi H, Mammeri S, Dib A, Pineda-Vargas CA, Msimanga M & Hedibel M

Semi empirical formula for electronic stopping power determination of 24Mg, 27Al and 28Si ions crossing Formvar foil in the ion energy domain of LSS theory

Radiation Physics and Chemistry, 95:205210, 2014

Kengne AP, Masconi K, Mbanya VN, Lekoubou A, Echouffo-Tcheugui JB & Matsha TE

Risk predictive modelling for diabetes and cardiovascular disease

Critical Reviews in Clinical Laboratory Sciences, 51(1):1-12, 2014

Kheswa NY, Papka P, Pineda-Vargas CA, Przybylowicz WJ, Steyn GF, Madiba TE & Sharpey-Shafer JF

Characterisation of thin solid Xe targets

Journal of Radioanalytical and Nuclear Chemistry, 299:1067-1072, 2014

Le Roux M, Phiri E, Khan W, Sakiroglu M, Valentine AJ & Khan S

Expression of novel cytosolic malate dehydrogenases (cMDH) in Lupinus angustifolius nodules during phosphorus starvation

Journal of Plant Physiology, 171:1609-1618, 2014

Macharia M, Kengne AP, Blackhurst DM, Erasmus RT & Matsha TE

The impact of chronic untreated hyperglycaemia on the long term stability of paraoxonase 1 (PON1) and antioxidant status in human sera

Journal of Clinical Pathology, 67:55-59, 2014

Matsha TE, Soita DJ, Hassan MS, Erasmus RT & Kengne AP

Deterioration, improvement of kidney function over time and determinants in the Cape Town Bellville South cohort

Nephrology, 19:638-647, 2014

Msimanga M, Pineda-Vargas CA, Hlatshwayo T, Comrie CM, Ammi H & Nkosi M

Electronic stopping force of 12C, 28Si and 63Cu ions in HfO2 and SiO2 dielectric films

Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms, 322:54-54, 2014

Pineda-Vargas CA, Topic M & Ntsoane T Micro-PIXE analysis of bioconductive hydroxyapatite coatings on titanium alloy

Journal of Radioanalytical and Nuclear Chemistry, 297:457-461, 2013

Oguntibeju O, Ayeleso AO & Brooks NL

Modulatory effects of rooibos and red palm oil on antioxidant status in streptozotocin-induced hyperglycemic male Wistar rats

Clinical Nutrition, 32(1):S219-220, 2013

Olafisoye OB, Fatoki OS, Oguntibeju OO & Osibote OA

Determination of trace and major elements in water on oil palm plantations by inductively coupled plasma-optical emission spectrometry

Instrumentation Science & Technology, 42(6):652666, 2014

Onyenekwu CP, Hoffmann M, Smit FC, Matsha TE & Erasmus RT

Comparison of LDL-cholesterol estimate using the Friedewald formula and the newly proposed de Cordova formula with a directly measured LDLcholesterol in a healthy South African population

Annals of Clinical Biochemistry, 51(6):672-679, 2014

Schloms L, Smith C, Storbeck KH, Marnewick JL, Swart P & Swart AC

Rooibos influences glucocorticoid levels and steroid ratios in vivo and in vitro: A natural approach in the management of stress and metabolic disorders?

Molecular Nutrition & Food Research, 58:537-549, 2014

Sobuwa S, Hartzenberg HB, Geduld H & Uys CS

Predicting outcome in severe traumatic brain injury using a simple prognostic model

SAMJ South African Medical Journal, 104(7):492494, 2014

Spicer RMF & Sobuwa S

An analysis of the validity of medical legal documentation in cases where the patient refuses treatment and/or transport

South African Journal of Bioethics and Law, 7(2):64-68, 2014

Thamahane-Katengua ETM, Marnewick JL, Ajuwon OR, Chegou NN, Szucs G, Ferdinandy P, Csont T, Csonka C & Van Rooyen J

The combination of red palm oil and rooibos show anti-inflammatory effects in rats

Journal of Inflammation – London, 11(41):1-12, 2014

Topic M, Khumalo Z & Pineda-Vargas CA

Studies on Pt-Mo phases using analytical techniques with high resolution

Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms, 318:163-167, 2014

Vergotine Z, Yako Y, Matsha TE, Kengne AP & Erasmus RT

Proliferator-activated receptor gamma Pro12Ala interacts with the insulin receptor substrate 1Gly972Arg and increases the risk of insulin resistance and diabetes in the mixed ancestry population from South Africa

BMC Genetics, 15(10):1-8, 2014

j ournal articles (not DHET subsidised)

Kotze MJ, Marnewick JL, Kidd M, Fisher LR & Van Velden DP

Assessment of the impact of hereditary factors on biochemical parameters of cardiovascular risk in relation to moderate alcohol consumption

Nutrition and Aging, 2:189-195, 2014

Kyei KA, Antwi WK, Opoku SY, Hermans S, Anim-Sampong S & Engel-Hills P Radiographers’ knowledge, attitude and challenges on pain management

The South African Radiographer, 52(1):22-25, 2014

Lekoubou A, Matsha TE, Sobngwi E & Kengne AP

Effects of diabetes mellitus on amyotrophic lateral sclerosis: A systematic review BioMed Central Research Notes, 7:171, March 2014

Matsha TE, Hassan MS, Hon GM, Soita DJ, Kengne AP & Erasmus RT

Derivation and validation of a waist circumference optimal cutoff for diagnosing metabolic syndrome in a South African mixed ancestry population

International Journal of Cardiology, 168(3):2954-2955, 2013

Nabasenje C, Davidson F, Kotze G & Engel-Hills P

Dose reference level for barium enemas at state hospitals in the Western Cape, South Africa

The South African Radiographer, 52(2):21-25, 2014

Nomakhosi M & Ramhurry C

An investigation into the effectiveness of light emitting diodes on treating melasma on skin type VI

American Journal of Dermatology and Venereology, 3(3):51-56, 2014

Odunaiya NA, Owonuwa DD & Oguntibeju OO

Ergonomic suitability of educational furniture and possible health implications in a university setting

Advances in Medical Education and Practice, 5:1-14, 2014

Parbhunath OL, Rautenbach F, Davison G & Marnewick JL

Optimization and validation of a reverse-phase high performance liquid chromatography assay with ultra-violet detection for measuring total L-ascorbic acid in food and beverage products

Journal of Analytical and Bioanalytical Techniques, 5(4):1-11, 2014

Swart AC, Schloms L, Smith C, Storbeck KH, Roos M, Marnewick JL & Swart P Rooibos tea: A functional food in the management of metabolic disorders

PharmaNutrition, 2(3):82-83, 2014

Technical reports

Abando C, Bonfiglioli AM, Coffey M, Engel-Hills P, Omar Y, Osztavics A, Rosenblatt E, Van de Velde G, Van Dyk J & Wadhawan GS

A Handbook for the Education of Radiation

Therapists (RTTs), Training Course Series: 58

(IAEA-TCS-58), International Atomic Energy Agency (IAEA), Vienna, 2014

Rheeder JP & Van der Westhuizen L

Multi-mycotoxin and mycological surveillance of small-holder farmers in four maize-growing provinces in South Africa, Maize Trust Project 12/01 Progress Report, August 2014

Postgraduate degrees conferred

DTech: Biomedical Technology

Ayepola OR

Effects of kolaviron, a Garcinia Kola biflavonoid, on biochemichal and histological parameters in streptozotocin-induced diabetes and diabetic complications (nephrotoxicity and hepatotoxicity) in male Wistar rats

Supervisors: Prof OO Ogunitbeju, Dr NL Brooks

MTech: Biomedical Technology

Atbayga AMA

In vitro cytotoxicity of titanium dioxide nanocomposites to be used in dental applications

Supervisors: Dr JA Mars, Prof D Gihwala

De Waal-Miller C

Determination of reference ranges for selected clinical laboratory tests for a medical laboratory in Namibia using pre-tested data

Supervisors: Prof AJ Esterhuyse, Prof B Noden

Madubedube JH

The role of FTO, ENPP1 and TCF7L2 in the pathogenesis of diabetes in an adult population from Bellville South, Cape Town,

South Africa

Supervisors: Prof TE Matsha, Dr Y Yako

Manirafasha C

The effect of kolaviron on epididymal and testicular function in streptozotocin-induced diabetic Wistar rats

Supervisors: Dr YG Aboua, Dr NL Brooks, Prof SS du Plessis

MTech: Dental Technology

Van der Poel NO

Mechanical retention of acrylic teeth onto a pure nylon base

Supervisors: Prof D Gihwala, Dr P van Zyl

MTech: Nursing

Egbera JI

Male university students’ knowledge, beliefs and attitude towards screening for prostate cancer in Benin City, Nigeria

Supervisors: Prof DD Khalil, Mrs F Kagee

Esau CAG

Prevention and management of occupational injuries in two higher education institutions of the Western Cape

Supervisors: Prof DD Khalil, Mrs A Dunn

Fugar EA

Exploring nurses’ role in the management of Ghanaian children diagnosed with cancer

Supervisor: Prof DD Khalil, Mrs A Dunn

Katjau I

Perceived factors that hinder the acceptance of contraceptives amongst the young adults in Outjo district, Namibia

Supervisors: Prof DD Khalil, Ms F Kagee, Mr S Hassan

Pretorius M

Knowledge and practices of occupational health nurse practitioners in the management of diabetes mellitus in South Africa

Supervisors: Prof DD Khalil, Mrs A Dunn, Mr S Hassan

MTech: Radiography Hartnick MD

Echocardiography for early detection of heart disease in high risk diabetic patients

Supervisor: Prof P Engel-Hills

Postgraduate degree obtained by a staff member

PhD Stellenbosch University

Grant KA

Analysis of the clinical utility of gene expression profiling in relation to conventional prognostic markers in South African patients with breast carcinomax