Biomaterials & Medical Devices

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New and Noteworthy Textbooks in

Biomaterials & Medical Devices from CRC Press

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Contents Nanomaterials ......................................................3 Complex Tissue & Organs....................................8 Engineering Cells ................................................12 Biotechnology ....................................................14 Materials Science ................................................16 Page 3

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Drug Delivery ....................................................21 Biomaterials Education........................................22 Medical Devices..................................................25 Industry Applications ..........................................30

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Nanomaterials New!

Nanoscience and Nanoengineering Advances and Applications Edited by

Ajit D. Kelkar, Daniel J.C. Herr. and James G. Ryan Joint School of Nanoscience and Nanoengineering, North Carolina A&T State University, Greensboro, USA

This book provides readers with a selection of recent breakthroughs in six nanotechnology platforms that exhibit high impact potential. These platforms include nanoelectronics, nanobiology, nanomedicine, nanomodeling, nanomanufacturing and related applications, and nanosafety. The chapters are designed to convey synergistic advances in understanding and application opportunities that can be achieved through an interdisciplinary approach to exploring each platform. Across each platform run thematic threads that help to reinforce the need for a multidisciplinary to understanding and leveraging nanoworld phenomena.

• Includes a framework for interdisciplinary nanoscale research • Serves as a catalyst for novel strategic research directions • Identifies entrepreneurial nanoengineering opportunities

Selected Contents: Introduction: The Mechanical and Biological Paradigms. Part 1 NANOELECTRONICS. NanoElectro-Mechanical Systems (Nems): Processes and Devices. A Study of Ga Assisted Growth of GaAs/GaAsSb Axial Nanowires by Molecular Beam Epitaxy. Applications of Micro/Nanotechnology in Design and Control of Neural Interfaces. Part 2 NANOBIO. Characterization Biological and Condensed Matter at the Nano Scale. Biological Nanostructures: Formation, Function, and Potential Applications. Part 3 NANO MEDICINE. Current Nanodelivery Systems for Imaging and Therapeutics.

Nanodevices and Systems for Clinical Diagnostics.

Fullerenes and Their Potential in Nanomedicine. Part 4 NANOMODELING. Modeling at Nano Scale – Material Chemistry Level Modeling in Processing and Mechanics of Engineered Materials. Computational Modeling of Bio-Nano Interfaces. Part 5 NANOLITHOGRAPHY AND NANOFABRICATION. Multi-scale Glass Fiber Reinforced Composite Developed from Epoxy Resin Containing Electrospun Glass Nanofibers. ...Part 6 NANOSAFETY. Towards Understanding Toxicity of Engineered Nanomaterials. ...

Catalog no. K22712, May 2014, 328 pp.

ISBN: 978-1-4822-3119-9, $159.95 / £99.00 Also available as an eBook

Nanomedical Device and Systems Design Challenges, Possibilities, Visions Edited by

Frank Boehm Independent Designer, Ontario, Canada

This volume articulates the development and implementation of beneficial advanced nanomedical diagnostic and therapeutic devices and systems, which may have strong potential toward enabling myriad paradigm shifts in the field of medicine. It presents conceptual and laboratory-derived examples of sophisticated, highly efficient, minimally invasive, and cost-effective nanomedical diagnostic and therapeutic strategies. It explores how these strategies might facilitate significantly increased accessibility to advanced medical procedures assisting those in both the developing and developed worlds. It also explores nanomedicine in human augmentation, longevity, and space travel.

• Presents innovative nanotechnological and biomimetically derived strategies in the design of potential nanomedical devices and their constituents • Contains several post-chapter Proposed Research Tasking Lists to facilitate the further investigation and potential development of specific nanomedical capacities • Includes eight chapters contributed by some of the leading experts in nanotechnology, nanomaterials, and nanomedicine

Selected Contents: Section I Envisaged Nanomedical Device and System Design Strategies. Exemplar Nanomedical Vascular Cartographic Scanning Nanodevice. Design Challenges and Considerations for Nanomedical Ingress and Egress. Design Challenges and Considerations for Nanomedical In Vivo Aqueous Propulsion, Surface Ambling, and Navigation. Design Challenges and Considerations for Nanomedical Energy Harvesting and Generation. ... Section II Merging with Reality: Nascent Nanomedical Diagnostics and Therapeutics. Nanomaterial-Based Electrochemical Biosensors. Gold Nanorods in Sensing and Nanomedical Applications. Ophthalmic Glucose Nanosensors for Diabetes Management. Sensorcyte Artificial Cells for Human Diagnostics and Analytics. ...

Section III Beyond the Event Horizon: Nanomedical Visions. Nanomedical Device and Systems Design in Remote Regions and the Developing World.

Nanomedical Device and Systems Design in Space Applications. ...

Catalog no. 7498, November 2013, 787 pp.

ISBN: 978-0-8493-7498-2, $179.95 / £114.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Nanomaterials New!

Nanopatterning and Nanoscale Devices for Biological Applications Edited by

Krzysztof Iniewski CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada

Seila Selimovic Harvard Medical School, Cambridge, Massachusetts, USA Series: Devices, Circuits, and Systems

Providing valuable insight into the latest developments in nanoscale technologies for the study of biological systems, this book covers device fabrication methods targeting the substrate on the nanoscale through surface modification. It discusses biosensors and integrated devices with nanoscale functionalities, and examines biological applications of nanoscale devices, including a review of nanotechnology in tissue engineering and regenerative medicine. It is especially useful to researchers in biological and biomedical engineering, electrical engineering, biophysics, biochemistry, and related disciplines.

• Offers a concise overview of nanofluidic and microfluidic approaches to biological problems • Presents the rapidly developing fields of nanofluidics and microfluidics in the context of biological and bioengineering research • Includes chapters dedicated to the utilization of nanopatterning methods and mass transport on nanofluidics platforms

Selected Contents: Section I: Fabrication. Nanopatterning through Self Assembly. Nanoscale Lithography. Materials for Nano- and Microscale Biological Applications.

Principles of Nano- vs. Microfluidics: Fluid Flow, Transport Phenomena, Particle Manipulation. Tailoring Wettability for Passive Fluid Control in Microfluidics.

Droplet-Based Microfluidics: Reactions and Analyses at the Picoliter Scale. Section II: Integration. Nanoscale Electrochemical and Optofluidic Biosensors. In Situ Nanotechnology-Derived Sensors for Ensuring Implant Success. Integrated Microscale Devices. Biosensors for Tissue Engineering. Deterministic Assembly to Add New Biosensing Capabilities to Si CMOS. Section III: General Application. Lab-on-Chip Technologies for Cell-Sensing Applications. DNA-Manipulation using Nano- and Microfluidics. Nanoscale Devices for Tissue Engineering and Drug Screening. Stem Cells-on-aChip: Stem Cells and Biomimetic Materials for Tissue Engineering and Regenerative Medicine. ...

Carbon Nanomaterials Second Edition Edited by

Yury Gogotsi and Volker Presser Drexel University, Philadelphia, Pennsylvania, USA Series: Advanced Materials and Technologies

This book provides information on synthesis, properties, and applications of carbon nanomaterials. With novel materials, such as graphene (atomically flat carbon) or carbon onions (carbon nanospheres), the family of carbon nanomaterials is rapidly growing.

The book provides a state-of-the-art overview and in-depth analysis of the most important carbon nanomaterials. Each chapter is written by a leading expert in the field which ensures that both a review on the subject along with emerging perspectives is provided to the reader.

Selected Contents: Graphene: Synthesis, Properties, and Applications Fullerene C60 Architectures in Materials Science Graphite Whiskers, Cones, and Polyhedral Crystals Epitaxial Graphene and Carbon Nanotubes on Silicon Carbide Cooperative Interaction, Crystallization, and Properties of Polymer–Carbon Nanotube Nanocomposites Carbon Nanotube Biosensors Carbon Nanostructures in Biomedical Applications Field Emission from Carbon Nanotubes Nanocrystalline Diamond. Carbon Onions Carbide-Derived Carbons Templated and Ordered Mesoporous Carbons Oxidation and Purification of Carbon Nanostructures Hydrothermal Synthesis of Nano-Carbons Carbon Nanomaterials for Water Desalination by Capacitive Deionization Carbon Nanotubes for Photoinduced Energy Conversion Applications Index Catalog no. K14293, October 2013, 529 pp.

ISBN: 978-1-4398-9781-2, $169.95 / £108.00 Also available as an eBook

Catalog no. K20286, July 2014, 392 pp.

ISBN: 978-1-4665-8631-4, $129.95 / £82.00 Also available as an eBook

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Nanomaterials Nanobiomaterials Development and Applications Edited by

Dong Kee Yi Gachon University, Gyeonggi-do, Republic of Korea

Georgia C. Papaefthymiou Villanova University, Pennsylvania, USA Series: Advances in Materials Science and Engineering

Nanobiotechnology serves as a bridge between nano and bio, with nanoscale materials providing the building blocks for the construction of the "bridge." This book gives you a broad, interdisciplinary view of advances and applications in bionanomaterials.

International contributors at the forefront of research in their disciplines explore a diverse set of topics.

Coverage includes biomimetic synthesis, bioimaging and cancer diagnosis, virus-enabled manufacturing of functional nanomaterials, tumor targeting, cytotoxicity, and more. The book demonstrates the importance of bionanomaterials to biotechnology, biomedicine, and environmental remediation.

Nanoporous Materials Advanced Techniques for Characterization, Modeling, and Processing Edited by

Nick Kanellopoulos Demokritos National Centre for Scientific Research, Greece

The past 30 years have seen a dramatic rise in the field of porous materials due to the development of an increasing number of novel materials. Designed for researchers from different disciplines, this book offers a clear and concise presentation of the state of the art, advances, and expected developments, as well as simulation techniques and their applications to optimize processes involving sorbents, membranes, and catalysts. The contributors address experimental modeling techniques and processes, presenting case studies to reinforce concepts.

Catalog no. K10550, February 2011, 578 pp.

ISBN: 978-1-4398-1104-7, $179.95 / £115.00 Also available as an eBook

Catalog no. K13550, August 2013, 490 pp.

ISBN: 978-1-4398-7641-1, $149.95 / £99.00 Also available as an eBook

Bioengineered Nanomaterials Edited by

Atul Tiwari University of Hawaii at Manoa, Honolulu, USA

Ashutosh Tiwari Linköping University, Sweden

This book presents in-depth information on bioengineered nanomaterials currently being developed in leading research laboratories around the world. In particular, the book focuses on nanomaterials for biomedical applications. Renowned international researchers discuss nanoemulsions as a vaccine adjuvant, bioceramic nanomaterials in medical applications, nanoporous membranes for cell encapsulation therapy, and inorganic nanoparticle materials for the controlled release of drugs. They also explore nanomedicine in brain tumor treatment, nanoparticles for the treatment of solid tumors and metastasis, and silver nanoparticles toxicity testing and bioapplications, among other topics.

Catalog no. K20269, August 2013, 436 pp.

ISBN: 978-1-4665-8595-9, $179.95 / £114.00 Also available as an eBook

The Nanobiotechnology Handbook Edited by

Yubing Xie University at Albany, College of Nanoscale Science and Engineering, New York, USA

Offering a uniquely thorough overview of nanobiotechnology and its place in today’s advancements in applied science, this comprehensive survey combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science, bioanalysis, and bioenergy to address the full scope of current and future developments. Worldclass experts discuss the role of nanobiotechnology in bioanalysis, biomolecular nanotechnology, biosensors, and the use of nanotechnology in biofuels.

Extensive references within each chapter facilitate further investigation into the field.

Catalog no. K11758, November 2012, 692 pp.

ISBN: 978-1-4398-3869-3, $169.95 / £108.00 Also available as an eBook

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Nanomaterials Nanotechnology The Whole Story Ben Rogers and Jesse Adams

RNA Nanotechnology and Therapeutics Edited by

NevadaNano, Sparks, USA

Peixuan Guo and Farzin Haque

Sumita Pennathur University of California, Santa Barbara, USA

This book communicates, in easy-to-understand language, the sometimes tough-tounderstand concepts of nanotechnology. It provides a comprehensive reference for technically interested/trained laymen in the general public who want to learn more about this revolutionary, highimpact field of technology. The amount and level of math used in the pedagogy of the text has been minimized to cater to a general audience. The book includes behind-the-scenes stories of Nobel-prize-winning scientists—completes with eureka moments—as well as back-of-the-envelope calculations showing the real numbers of nanotechnology.

Catalog no. K14290, March 2013, 395 pp.

ISBN: 978-1-4398-9780-5, $69.95 / £44.99 Also available as an eBook

Biosensors Based on Nanomaterials and Nanodevices Edited by

University of Kentucky, Lexington, USA

Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. The text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, RNA chemistry for nanoparticle synthesis, and conjugation and labeling.

Catalog no. K14577, July 2013, 611 pp.

ISBN: 978-1-4665-0566-7, $179.95 / £114.00 Also available as an eBook

Bionanotechnology Maheshwar Sharon IIT Bombay (retired), Birla College, Nanotechnology Research Center, India

Madhuri Sharon

Jun Li

Monad Nanotech Pvt. Limited, Mumbai, India

Kansas State University, Manhattan, USA

Nianqiang Wu West Virginia University, Morgantown, USA Series: Nanomaterials and their Applications

Linking leading interdisciplinary research, this book provides a comprehensive source for key advancements and future trends in nanostructured biosensor development. It describes the concepts, principles, materials, device fabrications, functions, system integrations, and applications of various biosensors based on signal transduction mechanisms. It explains how to utilize the unique properties of nanomaterials to construct nanostructured biosensors to achieve enhanced performance; includes examples of biosensors based on both typical and emerging nanomaterials; and inspires new ideas for tackling multiscale and multidisciplinary issues in the development of high-performance biosensors.

Highlighting the human applications of the science, this volume discusses the fundamental concepts and underlying science of bionanotechnology, and the bionanomachines that result from research into this exciting new field. Distilling the authors' research and groundbreaking original experimentation, chapters cover bionanomachines and their use with and manipulation of DNA, RNA, proteins, carbohydrates, and lipids. Well-documented and authoritative, this book offers students and scientists alike the foundational information required to advance this powerful and potentially life-altering field.

Catalog no. K12393, May 2012, 300 pp.

ISBN: 978-1-4398-5214-9, $79.95 / £49.99

Catalog no. K15174, December 2013, 517 pp.

ISBN: 978-1-4665-5151-0, $159.95 / £99.00 Also available as an eBook

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Nanomaterials Nanotechnology Understanding Small Systems, Second Edition Ben Rogers and Jesse Adams

Fundamentals of Microfabrication and Nanotechnology

NevadaNano, Sparks, USA

Third Edition, Three-Volume Set

Sumita Pennathur

Marc J. Madou

University of California, Santa Barbara, USA Series: Mechanical and Aerospace Engineering Series

This book works from the ground up to provide a detailed yet accessible introduction to one of the world’s fastest growing fields. It contains a clear presentation of real-world examples and original illustrations, as well as hundreds of homework problems of varying types, including multiple choice, true-false, indepth calculation, and essay (with complete solutions manual). This book uses a systems-based approach that illustrates how underlying areas of nano are assembled to create systems with unique functions and characteristics.

Catalog no. K12225, July 2011, 421 pp.

ISBN: 978-1-4398-4920-0, $104.95 / £66.99 Also available as an eBook

Nanobiomaterials Handbook Edited by

Balaji Sitharaman State University of New York at Stony Brook, USA

Nanobiomaterials exhibit distinctive characteristics which make them suitable for a variety of biological applications.

This volume provides a comprehensive overview of the field, offering a broad introduction for those new to the subject as well as a useful reference for advanced professionals. The book examines various synthesis and processing techniques important for developing nanobiomaterials, explores their unique nanoscopic physicochemical properties, discusses potential applications, and provides a detailed overview of the interactions between bionanomaterials/biological systems and the biocompatibility issues associated with bionanomaterials.

Catalog no. 94661, June 2011, 737 pp.

ISBN: 978-1-4200-9466-4, $179.95 / £115.00 Also available as an eBook

University of California, Irvine, USA

This text provides a theoretical and practical understanding of MEMS and NEMS. Expanded to three volumes to reflect substantial growth in the field, the first volume offers a rigorous theoretical treatment of micro- and nanosciences, and includes sections on solid-state physics, quantum mechanics, crystallography, and fluidics. The second volume presents a large set of manufacturing techniques for micro- and nanofabrication and covers different forms of lithography, material removal processes, and additive technologies. The third volume focuses on manufacturing techniques and applications of Bio-MEMS and BioNEMS. Catalog no. 3180, August 2011, 1992 pp.

ISBN: 978-0-8493-3180-0, $259.95 / £166.00

Nanotechnology in Tissue Engineering and Regenerative Medicine Edited by

Ketul Popat Colorado State University, Fort Collins, USA

Referred to as "nanomedicine" or "nanobiomedicine," the application of nanotechnology to medicine can impact diagnosis, monitoring, and treatment of diseases, as well as the control and understanding of biological systems. Bringing together an unparalleled field of experts, this volume explores various aspects of nanotechnology and its applications in biomedical fields. The book uses an application-oriented approach to relate laboratory-based research to the development of technologies that are easily adaptable to an industry environment, focusing chiefly on drug delivery, tissue engineering, and regenerative medicine.

Catalog no. K10090, November 2010, 302 pp.

ISBN: 978-1-4398-0141-3, $129.95 / £83.00 Also available as an eBook

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Nanomaterials Nano- and Biocomposites Edited by

Complex Tissues & Organs Tissue Engineering Principles and Practices

Alan Kin-tak Lau University of Southern Queensland, Australia and The Hong Kong Polytechnic University, Kowloon

Edited by

John P. Fisher University of Maryland, Kensington, USA

Farzana Hussain Oregon State University, Corvallis, USA

Antonios G. Mikos Rice University, Houston, Texas, USA

Khalid Lafdi University of Dayton, Ohio, USA

Advances in nanotechnology are leading to the creation of composites with a myriad of medical applications. This book melds research in biocomposites with advances in nanocomposite technology to provide an interdisciplinary resource on advanced materials for the biomedical industry. It brings together pioneering researchers who describe their contributions to the field. They cover nanostructured polymer composites and nano/bio composites. They look at developments in tissue engineering, safer resins for tooth and bone repair, and improved artificial joints. They also discuss potential opportunities for continued research.

Catalog no. 8027X, August 2009, 408 pp.

ISBN: 978-1-4200-8027-8, $184.95 / £118.00 Also available as an eBook

Joseph D. Bronzino Simsbury, Connecticut, USA

Donald R. Peterson University of Connecticut, Farmington, USA

This book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more.

The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. It also provides a very comprehensive overview of major research topics in tissue engineering.

• Includes contributions from experts and pioneers • Covers emerging topics such as regenerative medicine

Cadmium Telluride Quantum Dots

• Discusses the impact tissue engineering products could have on the future of medicine

Advances and Applications

Fundamentals: Strategic Directions. Calcium Phosphates. Protein Based Biomaterials. Synthetic Biomaterials. Morphogens. Signal Expression.

Embryonic Stem Cells. Hematopoietic Stem Cells.

Mesenchymal Stem Cells. Enabling Technologies: Nanobiomaterials. Biomimetics. Molecular Biology Techniques. Biomaterial Mechanics. Mechanical Conditioning. Micropatterned Surfaces. Drug Delivery.

Gene Therapy. Cell Engineering. Cell Encapsulation.

Cocultures. Bioreactors. Shear Forces. Vascularization.

Bioimaging. Modeling. Applications: Bone Engineering. Craniofacial Engineering. Tendon & Ligament Engineering. Cartilage Tissue Engineering.

TMJ Engineering. Interfacial Tissue Engineering. Dental Tissue Engineering. Urological Tissue Engineering.

Vascular Engineering. Neural Engineering. Engineering Tumors.

Edited by

John Donegan Yury Rakovich Trinity College Dublin, Ireland

Among nanomaterials, CdTe holds special technological importance as the only known II–VI material that can form conventional p–n junctions. This makes CdTe very important for the development of novel optoelectronic devices such as light-emitting diodes, solar cells, and lasers. This book focuses on CdTe quantum dots and addresses their synthesis, assembly, optical properties, and applications in biology and medicine. It makes for a very informative reading for anyone involved in nanotechnology and will also benefit those scientists who are looking for current research.

Catalog no. N10697, December 2013, 248 pp.

ISBN: 978-981-4316-05-7, $149.95 / £95.00 Also available as an eBook

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Selected Contents:

Catalog no. K13429, December 2012, 771 pp.

ISBN: 978-1-4398-7400-4, $149.95 / £95.00 Also available as an eBook

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Complex Tissues & Organs New!

Vascularization Regenerative Medicine and Tissue Engineering Edited by

Eric M. Brey Illinois Institute of Technology, Chicago, USA

This book presents the latest research and science on the process of vessel assembly, with an emphasis on methods for controlling the process for therapeutic applications. It has a strong orientation toward regenerative medicine and tissue engineering applications with contributions from engineers, basic scientists, and biologists. The book provides the reader with an understanding of the process of how blood vessels and methods for controlling this process are engineered in order to develop treatments for various pathologies and surgical situations.

Catalog no. K16910, August 2014, 396 pp.

ISBN: 978-1-4665-8045-9, $149.95 / £95.00 Also available as an eBook

University of the Witwatersrand, Johannesburg, South Africa

Wan-Ju Li University of Wisconsin, Madison, USA

This book bridges the gap between nanotechnology and regenerative medicine to facilitate the transition from the lab to the clinic. It compiles important aspects of basic science and fundamental principles for current nanotechnological innovations in biomaterials and cell, tissue, and organ engineering, and their clinical relevance. The book is intended for a wide audience including students, researchers, professors, and industrial experts working in the fields of biomaterial science and engineering, nanoscience and nanotechnology, bioengineering, cell biology, biomedical sciences, tissue engineering, and nanomedicine.

Catalog no. K13868, September 2012, 592 pp.

ISBN: 978-1-4398-8185-9, $149.95 / £95.00 Also available as an eBook

Bankura U

Teik-Che

SIM Univer

U. Rajen Ngee Ann

Catalog no. K13287, December 2012, 496 pp.

ISBN: 978-1-4398-7173-7, $179.95 / £109.00 Also available as an eBook

University of California, Davis, USA

Ugo Ripamonti

Subhaga

Therapeutic engineering (TE) is a cutting-edge domain in today’s era of medical technology research.

Through engineering algorithms that provide technological solutions, it aims to elevate the quality of life of disabled individuals. It describes therapeutic processes and mechanisms currently applied to healthcare in a range of areas, including mobility, communications, hearing, vision, and mental health and cognition. It will prove enlightening to researchers and practitioners in a host of disciplines who want to understand the recent advances achieved globally in the field of therapeutic engineering.

A Nano Approach

University of Turku, Finland

Chiba Univ

Wenwei Yu, Subhagata Chattopadhyay, Teik-Cheng Lim, and U. Rajendra Acharya

Articular Cartilage

Murugan Ramalingam Pekka Vallittu

Wenwei

Edited by

Tissue Engineering and Regenerative Medicine Edited by

Edited by

Advances in Therapeutic Engineering

Kyriacos A. Athanasiou Eric M. Darling Brown University, Providence, Rhode Island, USA

Grayson D. DuRaine and Jerry C. Hu University of California, Davis, USA

A. Hari Reddi University of California, Davis, School of Medicine, Sacramento, USA

Articular cartilage injuries, which are well known for their inability to heal, often degenerate inexplicably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. However, over the past two decades, there has been swift growth and development of new knowledge and technologies for cartilage formation, pathology, and repair. Written by world-class experts, this book covers all the latest research and clinical applications related to cartilage tissue engineering, including the role of nanotechnology.

Catalog no. K12457, March 2013, 439 pp.

ISBN: 978-1-4398-5324-5, $169.95 / £108.00 Also available as an eBook

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Complex Tissues & Organs Imaging in Cellular and Tissue Engineering

Polymers for Vascular and Urogenital Applications

Edited by

Hanry Yu and Nur Aida Abdul Rahim National University of Singapore Series: Series in Cellular and Clinical Imaging

As the field of tissue engineering moves from creating simpler outer body parts to more sophisticated internal organs, researchers need to evaluate and control how well the tissues are engineered and integrated into the living body. Suitable for both experts and newcomers in bioengineering and biomedical imaging, this book shows researchers how to apply imaging techniques to next-generation engineered cells and tissues. It helps them assess the suitability of specific imaging modalities for applications with various functional requirements.

Catalog no. K12139, May 2013, 298 pp.

ISBN: 978-1-4398-4803-6, $149.95 / £95.00 Also available as an eBook

Shalaby W. Shalaby, Karen J.L. Burg, and Waleed Shalaby Series: Advances in Polymeric Biomaterials

This book covers attributes of polymers used for vascular, urological, and gynecological materials. It provides a brief analysis of how the use of polymers in vascular and urogenital applications has evolved in the past five decades and outlines their common and specific functional requirements. It features small, readable monographs that provide a brief description of the evolving role of a particular material, and present topics in highly integrated, well-balanced, authoritatively prepared segments on materials processing and in vitro and in vivo evaluation.

Catalog no. 76949, May 2012, 270 pp.

ISBN: 978-1-4200-7694-3, $179.95 / £114.00 Also available as an eBook

Tissue Engineering

New!

The Law of Regenerative Medicine and Tissue Engineering

John P. Fisher University of Maryland, College Park, USA

Antonios G. Mikos Rice University, Houston, Texas, USA

David S. Smith Pepper Hamilton LLP, Pittsburgh, Pennsylvania, USA

Providing an overview of elements that can significantly impact the clinical introduction of cell- and tissue-based products, this text is an important reference at both the federal and state level. It discusses guidelines for the numerous current clinical trials for complex tissue constructs and cell therapies and considers the development of strategies for building patent portfolios for the increasing number of companies commercializing skin substitutes, expanded cell populations for cartilage repair, and extracellular materials intended to enable remodeling or repair at the implementation site.

Catalog no. K11293, December 2014, 270 pp.

Soft Cover, ISBN: 978-1-4398-2650-8 $59.95 / £38.99 Also available as an eBook

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Edited by

Joseph D. Bronzino Trinity College, Hartford, Connecticut, USA

The ability to engineer biocompatible tissue is the hallmark of modern biomedical engineering, integrating all aspects of every sub-discipline in the field. Bringing in a diverse group of international contributors with backgrounds in academia, clinical medicine, and industry, this volume surveys advances in this relatively young area. It discusses the fundamental concepts of tissue engineering, enabling technologies, and tissue engineering applications. It examines strategies that incorporate scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques that are being applied in regenerative medicine.

Catalog no. 9026, May 2007, 600 pp.

ISBN: 978-0-8493-9026-5, $109.95 / £69.99 Also available as an eBook

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Complex Tissues & Organs New!

New!

Skin Bioscience

Tissue and Organ Regeneration

A Molecular Approach Edited by

Toyoko Imae National Taiwan University of Science & Technology, Taipei

This text introduces skin bioscience with a specific focus on the molecular approach. Following the description of the fundamental structure and unique functionality of the skin, it examines the response of the skin to exterior stimulation. It also focuses on the beautification and regeneration of the skin. The book provides readers with the molecular knowledge of the skin and stimulates their interest in further investigation and development of skin bioscience.

Catalog no. N10701, February 2014, 240 pp.

ISBN: 978-981-4364-95-9, $149.95 / £95.00 Also available as an eBook

Advances in Microand Nanotechnology Edited by

Lijie Grace Zhang, Ali Khademhosseini, and Thomas Webster Edited by three of the top researchers in the field of tissue engineering and nanomedicine, with contributions from a team of pioneers and well-known leading experts in the biomedical field, this book presents the latest nano/microtechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. It covers and details cutting-edge research in nano/microfabrication techniques and biomaterials for various tissues/organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, and cardiovascular tissue, and regenerations.

Catalog no. N10888, March 2014, 800 pp.

ISBN: 978-981-4411-67-7, $169.95 / £108.00 Also available as an eBook

New!

New!

Biomechanics of Artificial Organs and Prostheses

Scaffolds for Tissue Engineering

Megh R Goyal University of Puerto Rico (retired professor) Series: Advances in Bioengineering Research and Applications, Volume 2

Artificial organs are one of the world’s greatest advancements in medicine. This book covers cardiopulmonary bypass surgery; artificial hearts and pacemakers; stenting and ballooning; artificial lungs, kidneys, and knees; dental protheses; and more. It is a one-stop source of basic knowledge and techniques necessary to understand, design, develop, and evaluate artificial organs and prostheses. It covers the basic principles and applications, types and mechanics, and biomaterials. It is a must for physicians, scientists, and educators.

Catalog no. N11052, February 2014, 634 pp.

ISBN: 978-1-926895-84-0, $149.95 / £95.00 Also available as an eBook

Biological Design, Materials and Fabrication Edited by

Claudio Migliaresi and Antonella Motta University of Trento, Italy

This book illustrates design principles for scaffolds for tissue engineering with particular relevance to the biological requirements needed to control and drive the biological cross-talk, and reviews materials and fabrication and validation methods. The book is mainly addressed to graduate and post-graduate students, who are approaching tissue engineering or experienced researchers who wish to have condensed but comprehensive information on materials, fabrication techniques, biological principles, and design criteria.

The contributors are among the scientific leaders in their respective fields.

Catalog no. N10887, June 2014, 350 pp.

ISBN: 978-981-4463-20-1, $149.95 / £95.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Engineering Cells Stem Cell Engineering

Mechanics of Cellular Bone Remodeling

Principles and Practices Edited by

David Schaffer University of California - Berkeley, USA

Joseph D. Bronzino

Coupled Thermal, Electrical, and Mechanical Field Effects Qing-Hua Qin Australian National University, Canberra, Acton

Simsbury, Connecticut, USA

Donald R. Peterson University of Connecticut, Farmington, USA

With contributions from pioneers and experts, this book provides a broad overview of the challenges of stem cell engineering. It discusses advances made during the last decade that have led to increasingly defined culture systems for growing human ES cells.

The book highlights recent advances in the understanding of the cellular and molecular composition of the hematopoietic stem cell niche, as well as approaches to build upon this basic information to direct stem cell differentiation into blood cell lineages.

Catalog no. K13309, November 2012, 221 pp.

ISBN: 978-1-4398-7204-8, $99.95 / £63.99 Also available as an eBook

Bacterial NanoCellulose A Sophisticated Multifunctional Material

Research on bone remodeling has resulted in new information and has led to improvements in design and biomedical practices. This volume presents a unified exploration of recent advances, giving readers a sound understanding of bone remodeling and its mathematical representation. The book details the development of each of the techniques and ideas.

From there it progresses to the derivation and construction of multifield and cellular bone remodeling and examines how they arise naturally in response to external multifield loads.

Catalog no. K16026, January 2013, 320 pp.

ISBN: 978-1-4665-6416-9, $139.95 / £89.00 Also available as an eBook

Biomaterials for Stem Cell Therapy State of Art and Vision for the Future

Edited by

Edited by

Miguel Gama, Paul Gatenholm, and Dieter Klemm

Loredana De Bartolo Institute on Membrane Technology, Rende, Italy

Series: Perspectives in Nanotechnology

Center for Biotechnology and Biomedicine (BBZ), Leipzig, Germany

This seminal work covers the basic science, technology, and economic impact of this bulk chemical as well as the companies and patents that are driving the field. It reviews the biosynthesis and properties of BC, including genetics and characterization; discusses the advancing technology as it relates to product development, bioreactors, and production; and analyzes the economic impact of BC on a diverse range of industry applications, including materials and biomaterials, biological and polymer sciences, and electromechanical engineering.

Catalog no. K13216, November 2012, 304 pp.

ISBN: 978-1-4398-6991-8, $129.95 / £82.00 Also available as an eBook

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Augustinus Bader This book provides state-of-the-art developments with a specific focus. It details the interaction of stem cells with biomaterials for constructing and regenerating tissues and organs integrating strategies from basic biology, to materials for remodeling, to production processes. It discusses stem cells of embryonic and adult origin with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair, and cardiovascular therapy.

It includes developments in the field reflecting the design and construction of the human body and its principal anatomy.

Catalog no. K16738, January 2013, 662 pp.

ISBN: 978-1-4665-7639-1, $199.95 / £127.00 Also available as an eBook

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Engineering Cells Biology of Oral Cancer Key Apoptotic Regulators Prakash S. Bisen Defense Research & Development Establishment, Gwalior, India

Zakir Khan Institut Curie, Orsay, France

Saurabh Bundela Department of Post Graduate Studies and Research in Biological Sciences, Rani Durgawati University, Jabalpur, India

Cancer is a class of disease or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues. One new approach in dealing with cancer is through apoptotic regulators, the process of controlling cell growth by abnormally prolonging cell survival, facilitating the accumulation of transforming mutations and promoting resistance. This book uses oral cancers as the specific means to demonstrate this technique with this particular type of cancer, which is quite prevalent in India and other parts of Asia.

Catalog no. K16715, July 2013, 292 pp.

ISBN: 978-1-4665-7558-5, $139.95 / £89.00 Also available as an eBook

Mechanobiology Handbook Edited by

Jiro Nagatomi Clemson University, South Carolina, USA

Mechanobiology examines the effects of mechanical force stimuli on cellular biological functions. At appropriate levels, mechanical stimuli are necessary for the growth and maintenance of healthy tissues and organs. The past two decades have seen a dramatic increase in the level of research in mechanobiology. This volume presents basic materials in mechanics and cell biology. The book is an appropriate reference for those new to the field and is designed to stimulate new ways of thinking in current mechanobiology researchers.

Catalog no. 91212, March 2011, 563 pp.

ISBN: 978-1-4200-9121-2, $179.95 / £115.00 Also available as an eBook

Biomaterials and Stem Cells in Regenerative Medicine Edited by

Murugan Ramalingam Seeram Ramakrishna National University of Singapore

Serena Best University of Cambridge, UK Series: BASEES/Routledge Series on Russian and East European Studies

This book brings together current knowledge on biomaterials and stem cells in the context of tissue engineering and regenerative medicine. It explores key scientific and clinical aspects, including the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications. Coverage ranges from fundamental principles to advances at the macro, micro, nano, and molecular scales. The book bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities.

Catalog no. K13711, July 2012, 564 pp.

ISBN: 978-1-4398-7925-2, $149.95 / £95.00 Also available as an eBook

Handbook of Therapeutic Biomarkers in Cancer Edited by

Sherry X. Yang National Cancer Institute, Bethesda, Maryland, USA

Janet E. Dancey Ontario Institute for Cancer Research, Toronto, Canada

In this volume, a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions.

This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology.

Catalog no. N10578, June 2013, 518 pp.

ISBN: 978-981-4364-65-2, $179.95 / £114.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Biotechnology New!

Biotechnology in Medical Sciences Firdos Alam Khan Manipal University, Dubai, UAE

This book is a comprehensive overview of all the important aspects of medical biotechnology intended for interested, scientifically oriented laypersons, along with those who want a relatively low-level presentation of important biotechnology medical specialties such as bacteriology, immunology, recombinant DNA, molecular diagnostics, gene therapy, synthetic biology, tissue engineering, bioethics, IP issues, vaccines, and more.

• Provides a holistic view of all aspects of medical biotechnology, from labs to clinics • Presents major medical biotechnology events, research, and breakthroughs in chronological order • Includes a bibliography at the end of each chapter to encourage further study • Contains colorful illustrations to clarify key topics

New!

Foam Fractionation Principles and Process Design Paul Stevenson and Xueliang Li University of Auckland, New Zealand

This book explains the underlying physics of foam fractionation, describes process intensification strategies, provides design guidance for plant-scale installations, contains the latest knowledge of foam fractionation transport processes, and presents a case study of the world’s largest commercial foam fractionation plant producing the food preservative Nisin. It capitalizes on the authors’ extensive practical experience of foam fractionation and allied processes to give process engineers, industrial designers, chemical engineers, academics, and graduate students a greater understanding of the mechanistic basis and real-world applications of foam fractionation.

• Delivers a systematic explanation of the underlying physics of foam fractionation

• Dedicates an entire chapter to career opportunities

• Discusses the fundamentals of molecular adsorption to gas liquid interfaces and the dynamics of foam

Selected Contents:

• Describes foam fractionation process intensification strategies

Introduction to Biotechnology in Medical Sciences Human Diseases: Causes and Reasons Bacteriology and Antibiotics Virology and Vaccines Immunological Disorders & Immunotherapy Recombinant DNA Technology and Therapeutic Proteins Stem Cell Technology Cell and Tissue Engineering Molecular Diagnostics and Forensic Science Genetic Disorders and Gene Therapy Synthetic Biology and Nanomedicine Pharmacogenomics and Predictive Medicine Bioethics Biobusiness and Intellectual Property Rights Career Opportunities Glossary Catalog no. K22340, June 2014, 480 pp.

ISBN: 978-1-4822-2367-5, $79.99 / £119.95 Also available as an eBook

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• Contains the latest knowledge of foam fractionation transport processes

Selected Contents: Introduction Adsorption of Surface Active Species to Gas-Liquid Interfaces Hydrodynamics of Pneumatic Foam Mechanisms of Foam Instability Hydrodynamics of Bubble Swarms Modes of Operation Bubble Production and Foamate Recovery Column and Process Design Process Intensification Case Study: The Production of Nisin Catalog no. K15518, February 2014, 206 pp.

ISBN: 978-1-4665-5851-9, $229.95 / £146.00 Also available as an eBook

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Biotechnology Biotechnology Fundamentals Firdos Alam Khan Manipal University, Dubai, UAE

Biological and Biomedical Coatings Handbook Two-Volume Set Edited by

Sam Zhang Nanyang Technological University, Singapore Series: Advances in Materials Science and Engineering

Important in today’s nanotechnology, biological and biomedical coatings have been studied extensively and are receiving much attention from researchers. A timely reference for experts and newcomers, this handbook explores the latest developments in films and coatings for biological and biomedical applications. The text covers a wide array of material types, including sol-gel, bio-ceramics, polymers, glass, nanomaterials, and chitosan. It also addresses various processes for developing and implementing these coatings, including CVD and PVD, drug delivery, released-control coatings, and spectroscopy.

• Covers processing, properties, and performance • Discusses sol-gels, bio-ceramics, polymers, glasses, nanomaterials, and other materials • Explores CVD and PVD • Includes information on drug delivery and released-control coatings • Presents cutting-edge developments from world leaders in films and coatings research • Serves as a simplified introductory stepping stone for new entrants to the field • Gives experts up-to-date figures, tables, plots, and images to aid their own work Catalog no. K11126, May 2011, 976 pp.

ISBN: 978-1-4398-2125-1, $259.95 / £166.00 Also available as an eBook

Biological and Biomedical Coatings Handbook Applications

Catalog no. K12270, May 2011, 520 pp.

ISBN: 978-1-4398-4996-5, $146.95 / £94.00 Also available as an eBook

Biological and Biomedical Coatings Handbook Processing and Characterization

Catalog no. K12269, May 2011, 456 pp.

ISBN: 978-1-4398-4995-8, $146.95 / £94.00 Also available as an eBook

This textbook discusses the fundamentals of biotechnology as well as the latest developments such as stem cell research, cloning, biofuel, transgenic plants, genetically modified food or crops, pharmacogenomics, and nano-biotechnology. Incorporating extensive pedagogy into the content, the authors provide examples, end-of-chapter problems case studies, and laboratory tutorials. They include definitions, historical perspectives, time lines, and major discoveries along with the major segments of biotechnology, products, current research and development, career prospects, ethical issues, and future trends.

Catalog no. K11059, September 2011, 608 pp.

ISBN: 978-1-4398-2009-4, $93.95 / £49.99 Also available as an eBook

OMICS Applications in Biomedical, Agricultural, and Environmental Sciences Edited by

Debmalya Barh, Vasudeo Zambare, and Vasco Azevedo Featuring contributions from active researchers around the world, this book explores current and emerging fields such as glycomics, miRNA, metagenomics, and environomics and their various applications. In one volume, it examines a wide range of applications across the life sciences, demonstrating the real diversity of omics. This timely book discusses toxicogenomics in the assessment of environmental pollutants, plant metabolomics, nutrigenomics and its therapeutic applications, microalgal omics, omics for biofuel development, omics approaches for crop improvement and environmental sustainability, breast cancer biomarkers, and much more.

Catalog no. K15973, March 2013, 713 pp.

ISBN: 978-1-4665-6281-3, $169.95 / £108.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Biotechnology OMICS

Materials Science New!

Orthopaedic Biomaterials in Research and Practice

Biomedical Perspectives and Applications Edited by

Debmalya Barh Institute of Integrative Omics and Applied Biotechnology (IIOAB), Purba Medinipur, West Bengal, India

Second Edition Kevin L. Ong Exponent Inc., Philadelphia, Pennsylvania, USA

Kenneth Blum and Margaret A. Madigan

Scott Lovald

LifeGen, San Diego, California, USA

Jonathan Black

A reflection of the explosion of research and development in this field, this book explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. It collates recent developments in the field into a state-of-the-art framework for this discipline. A select panel of experts discusses their cutting-edge omics research and novel technologies, supplying a basic platform of methods and applications as well as a multi-omics approach to future endeavors in the fertile areas of omics research.

Clemson University (Professor Emeritus), South Carolina, USA

Catalog no. K12277, November 2011, 613 pp.

ISBN: 978-1-4398-5008-4, $159.95 / £99.00 Also available as an eBook

Biotechnology Operations Principles and Practices

Extensively revised, this text explores the biomaterials aspects of research on and treatment of injuries, disabilities, and diseases of the musculoskeletal system, emphasizing properties of natural soft and hard tissues and of materials used to replace or treat them, and the interactions between native tissues and manmade (engineered) materials. It is intended for use in both teaching and self-study settings. The work introduces materials science as applied to medical research and treatment (biomaterials) for students and practitioners who may lack formal training in engineering.

• Focuses directly on the biomaterials aspects of orthopaedic research and practice • Supplies worked problems, problems to solve and a self-test • Includes a comprehensive glossary of engineering terms • Provides references at the end of each chapter

Selected Contents:

Michael J. Roy University of Wisconsin-Madison, Madison, USA

This book introduces key biotechnology developments and covers critical elements, such as project management, regulatory affairs, quality assurance, biomanufacturing, quality control, nonclinical safety testing, and clinical evaluation. The author discusses these subjects in relation to development planning, process and pathways, management of integrated projects, and the business and economic aspects of development.

Using simple language and explanatory figures, it describes the functional areas that must be successfully integrated to safely and efficiently bring a biotechnology product to market.

Catalog no. K11486, March 2011, 416 pp.

ISBN: 978-1-4398-3027-7, $104.95 / £66.99 Also available as an eBook

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Exponent, Inc., Menlo Park, California

Forces and Equilibrium Deformation Mechanical Properties Viscoelasticity Properties of Natural Materials Polymers Metals Ceramics and Composites Tissue engineering Hybrid, Combination and Replant Materials Friction and Wear Corrosion and Degradation Fixation Host Response Testing and Introduction of New Materials Materials Retrieval and Analysis Annotated Bibliography Index Catalog no. K14467, February 2014, 476 pp.

ISBN: 978-1-4665-0350-2, $179.95 / £114.00 Also available as an eBook

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Materials Science Marine Biomaterials Characterization, Isolation and Applications Edited by

Se-Kwon Kim Pukyong National University, Busan, South Korea

Bringing together a wide range of research in this important area, this book includes the latest developments and applications of marine-derived biomaterials, from preliminary research to clinical trials. Essential reading for the novice and expert alike, it details the isolation and characterization of biomaterials and their biological activities, including antiviral, anti-allergic, and anticoagulant effects. The book also discusses the viability of low-cost marine biomaterials, biomedical applications such as tissue engineering and drug delivery, and commercialization of marine-derived products.

• Offers very thorough coverage of isolation and characterization as well as the industrial and medical applications of marine materials • Details various approaches for the extraction and application of marine materials, such as those pertaining to tissue engineering • Contains an extensive reference list in each chapter to encourage further study

New!

Computational Bioengineering Guigen Zhang Clemson University, South Carolina, USA

Computational bioengineering takes advantage of the latest computational capabilities to deal with scientific and engineering problems associated with the field of bioengineering, using a multidisciplinary approach. This book introduces readers to the need and power of multidisciplinary computer modeling to advance a number of critical areas within bioengineering. It contains comprehensive coverage of the interplay of multiple governing principles underlying common biomedical devices and problems. Many of the contributors are world-class experts and appropriate case studies are included.

Catalog no. K15115, September 2014, 700 pp.

ISBN: 978-1-4665-1755-4, $179.95 / £114.00 Also available as an eBook

Biomaterials Principles and Practices

Selected Contents:

Edited by

Part I: Isolation and Characterization of Marine Biomaterials Part II Biological Activities of Marine Biomaterials Part III Biomedical Applications of Marine Biomaterials Part IV: Industrial Applications of Marine-Derived Biomaterials Index

Joyce Y. Wong

Catalog no. K14576, April 2013, 840 pp.

ISBN: 978-1-4665-0564-3, $189.95 / £121.00 Also available as an eBook

Most current applications of biomaterials involve structural functions. Complex chemical functions such as those of the liver and complex electrical or electrochemical functions such as those of the brain and sense organs cannot be carried out by biomaterials at this time. With these basic concepts in mind, this book focuses on biomaterials consisting of different materials such as metallic, ceramic, polymeric, and composite. It highlights the impact of recent advances in the area of nano- and microtechnology on biomaterial design.

Boston University, Massachusetts, USA

Joseph D. Bronzino Simsbury, Connecticut, USA

Donald R. Peterson University of Connecticut, Farmington, USA

Catalog no. K13339, December 2012, 281 pp.

ISBN: 978-1-4398-7251-2, $139.95 / £89.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Materials Science Szycher's Handbook of Polyurethanes, Second Edition Edited by

Michael Szycher, Ph.D

Biomaterials Science An Integrated Clinical and Engineering Approach

Sterling Biomedical, Inc., Lynnfield, Massachusetts, USA

Edited by

Written as a reference for polyurethane technologists and end users, raw materials suppliers, and students in the field, this second edition covers the technical advances in the field over the past ten years. Filled with tables, charts, and photographs, it includes new data on green polyurethanes, automotive applications, new coatings, new manufacturing equipment, new health-care uses, and more. Individuals from all major polyurethane intermediate suppliers and equipment manufacturers contributed to this updated handbook, and discuss current products and provide a comprehensive list of product portfolios.

Superior NanoBioSystems, Silver Spring, Maryland, USA

Catalog no. K11811, July 2012, 1144 pp.

ISBN: 978-1-4398-3958-4, $199.95 / £127.00 Also available as an eBook

Yitzhak Rosen Noel Elman Cambridge, Massachusetts, USA

This book approaches biomaterials science not just from materials science and engineering perspectives, but also from the clinical side. It integrates both fields at many levels, helping them increase the rate of successful deployment of biomaterials, lower the side effects of such a deployment, and accumulate knowledge for improving current methodologies and meeting future challenges. Leading contributors address topics such as hemocompatibility, carcinogenesis, infections, and cellular mechanisms, as well as signal transduction, clinical trials, MEMS, nanotechnology, FDA regulations, and ethical issues.

Catalog no. K10223, June 2012, 310 pp.

ISBN: 978-1-4398-0404-9, $149.95 / £95.00 Also available as an eBook

Corrosion of Ceramic Materials

Materials in Biology and Medicine Edited by

Third Edition

Sunggyu Lee

Ronald A. McCauley

Ohio University, Athens, USA

Rutgers, The State University of New Jersey, Piscataway, USA

David Henthorn St. Louis University, Missouri, USA

Series: Corrosion Technology

Series: Green Chemistry and Chemical Engineering

With an abundance of practical features and new information, this expanded and completely reorganized third edition helps readers address corrosion problems and create the most corrosion-resistant systems possible.

Reflecting the many changes in the field since the publication of the second edition, the book includes new chapters on corrosion by biological sources as well as corrosion of architectural materials. This edition also contains more questions and examples, additional material on thermal and environmental barrier coatings, an expanded chapter on composites, and new literature sources.

With peer-reviewed chapters written by a select group of academic and industry experts, this comprehensive yet accessible book covers the most advanced materials used in biology and medicine. The book focuses on biomaterials and bioinspired materials, functional and responsive materials, controlling biology with materials, and the development of devices and enabling technologies. It will help readers tackle challenges of novel materials, carry out new process and product development projects, and create new methodologies for applications that enhance the quality of life.

Catalog no. K13848, March 2012, 260 pp.

ISBN: 978-1-4398-8169-9, $169.95 / £108.00 Also available as an eBook

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Catalog no. K11066, January 2013, 462 pp.

ISBN: 978-1-4398-2022-3, $159.95 / £99.00 Also available as an eBook

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CJN01_5.5x8.5_MC_Temp 4/30/14 12:36 PM Page 19

Materials Science Hydroxyapatite Coatings for Biomedical Applications Edited by

Sam Zhang Nanyang Technological University, Singapore Series: Advances in Materials Science and Engineering

With a bonelike structure that promotes osseointegration, hydroxyapatite (HA) coating can be applied to otherwise bioinactive implants to make their surface bioactive, thus achieving faster healing and recovery.

This book explores developments in the processing and property characterization and applications of hydroxyapatite, providing a timely resource for active researchers and newcomers to the field. HA experts from the United States, Japan, Singapore, and China present valuable insights on topics ranging from deposition processes to applications in orthopedic and dental implants and drug delivery.

Catalog no. K14030, May 2013, 469 pp.

ISBN: 978-1-4398-8693-9, $219.95 / £140.00 Also available as an eBook

Polymer and Polymer-Hybrid Nanoparticles From Synthesis to Biomedical Applications Stanislav Rangelov Asterios Pispas Polymeric and hybrid nanoparticles have received increased scientific interest in terms of basic research as well as commercial applications. This book covers an array of topics from polymer synthesis and macromolecular design to possible biomedical applications. The authors present a well-rounded picture of objects ranging from simple polymeric micelles to complex hybrid polymer-based nanostructures, detailing synthetic procedures, techniques for characterization and analysis, properties, and behavior in select solvents and dispersions. They summarize important developments in the field, condensing the relevant research into a comprehensive resource.

Catalog no. K13166, August 2013, 499 pp.

ISBN: 978-1-4398-6907-9, $149.95 / £95.00 Also available as an eBook

Optical Techniques in Regenerative Medicine Edited by

Stephen P. Morgan, Felicity R. Rose, and Stephen J. Matcher This practical book illustrates how to use optical imaging techniques and instrumentation for the fabrication, assessment, and longitudinal monitoring of regenerative medicine therapies. It covers optical coherence tomography, acousto-optic imaging, Raman spectroscopy, machine vision, bioluminescence, second harmonic generation microscopy, multi-photon microscopy, coherent anti-Stokes Raman scattering, fluorescence spectroscopy, and light scattering spectroscopy. Each chapter provides an overview of a particular technique, its advantages and limitations in terms of structural and functional information, and examples of applications in regenerative medicine.

Catalog no. K12560, August 2013, 438 pp.

ISBN: 978-1-4398-5495-2, $129.95 / £82.00 Also available as an eBook

Polymeric Biomaterials 2 Volume Set, Third Edition Edited by

Severian Dumitriu University of Sherbrooke, Quebec, Canada

Valentin Popa Technical University of Iasi, Romania

The third edition of a bestseller, this comprehensive reference presents the latest polymer developments and most up-to-date applications of polymeric biomaterials in medicine. This substantially larger resource contains 53 chapters in two volumes, which include state-of-the-art research and successful breakthroughs in applications that have occurred in the last ten years. Completely revised and expanded, the third edition covers the structure and properties of synthetic and natural polymers as well as applications of polymeric biomaterials including drug delivery, tissue engineering, anticancer therapies, hydrogels, and bioartificial organs.

Catalog no. 94726, January 2013, 1710 pp.

ISBN: 978-1-4200-9472-5, $329.95 / £210.00 Also available as an eBook

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Materials Science Biological and Medical Sensor Technologies Edited by

Krzysztof Iniewski CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada Series: Devices, Circuits, and Systems

This book contains contributions from experts exploring the development and use of sensors in biological and medical applications. It covers advanced sensing and communications, modeling of DNA-derivative architecture, and the use of enzyme and quartz crystal microbalance-based biosensors. It also addresses biosensors in human behavior measurement, sweat rate wearable sensors, and the future of medical imaging, including developments in spatial and spectral resolution of semiconductor detectors. Contributors discuss application of high-resolution CdTe detectors in gamma ray imaging and recent advances in positron emission tomography technology.

Catalog no. K13895, February 2012, 412 pp.

ISBN: 978-1-4398-8267-2, $149.95 / £95.00 Also available as an eBook

Functions and Applications Edited by

Kangde Yao, Junjie Li, Fanglian Yao, and Yuji Yin Tianjin University, China

This work details the latest progress in the research and development of chitosan-based biomaterials, providing the foundation for future research. The book introduces the formation and chemical structure of chitosan-based hydrogels. It also discusses the relationship between their structure and functions, which provides a theoretical basis for the design of biomaterials. In addition, many real-world examples illustrate the potential application of chitosan-based hydrogels in various fields, including materials science, biotechnology, pharmaceuticals, regenerative medicine, and cell engineering.

Catalog no. K11120, July 2011, 521 pp.

ISBN: 978-1-4398-2114-5, $199.95 / £127.00 Also available as an eBook

Polyurethane Shape Memory Polymers

Physical Properties of Materials

W.M. Huang

Second Edition Mary Anne White Dalhousie University, Halifax, Nova Scotia, Canada

Designed for advanced undergraduate students, this bestselling text establishes the principles that control the optical, thermal, electronic, magnetic, and mechanical properties of materials.

This fully revised and updated second edition now covers materials sustainability, crystalline structures, graphene, carbon nanotubes, nanocomposites, quantum dots, magnetocaloric effect, spintronics, and polymer classifications. It also includes a new capstone tutorial on the materials science of cymbals, more than 60 new end-of-chapter problems, and updated references. A host of ancillaries are available on a companion website.

Catalog no. K12969, June 2011, 469 pp.

ISBN: 978-1-4398-6651-1, $83.95 / £52.99 Also available as an eBook

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Chitosan-Based Hydrogels

Nanyang Techological University, Singapore

Bin Yang Helvoet Rubber & Plastic Technologies Pte Ltd., Singapore

Yong Qing Fu Heriot Watt University, Edinburgh, UK

An important member of the smart materials family, the shape memory polymer has attracted serious attention as a result of its ability to recover its original shape after having a stimulus applied to them. This book provides the full story of polyurethane-based shape memory polymers, including discussion of thermomechanical properties and behavior of the polymer and its composites. It also addresses the modification of the shape memory polymer and introduces novel actuation mechanisms, as well as presenting the wide range of state-of-the-art (and potential) applications.

Catalog no. K11723, September 2011, 383 pp.

ISBN: 978-1-4398-3800-6, $189.95 / £121.00 Also available as an eBook

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CJN01_5.5x8.5_MC_Temp 4/30/14 12:36 PM Page 21

Materials Science

Drug Delivery

Handbook of Oral Biomaterials

Nanomedicine in Drug Delivery

Edited by

Arun Kumar

Jukka Pekka Matinlinna University of Hong Kong, Sai Ying Pun

The book introduces the latest advances in dental materials and biomaterials science. It covers ceramic, metallic, and polymeric oral biomaterials. The contributing authors are from all over the world and are distinguished in their disciplines. A solid primer for dental students, the book is also highly recommended for students of engineering and basic science who want to gain an insight in contemporary biomaterials science. For medical practitioners, the book offers an invaluable opportunity to learn about the latest steps in dental biomaterials.

Selected Contents: Bonding to Dentin and Enamel. Biomineralization and Biodemineralization of Enamel. Materials in Dentistry.

Biomechanics in Dentistry. Biocompatibility. Resinbased Cements used in Dentistry. Glass Fibers in Fiber-reinforced Composites. Bioactive Glasses.

Biological Activity of Titanium. Titanium in Implant Dentistry. Surface Pretreatment Methods and Silanization. Sol-Gel Coatings on Titanium. Internal Fixation in Oral and Maxillofacial Surgery. Zirconia and Implant Dentistry. Bonding to Zirconia. ...

Catalog no. N10876, April 2014, 600 pp.

ISBN: 978-981-4463-12-6, $249.95 / £159.00 Also available as an eBook

Edited by University of Delaware, Newark, USA

Heidi M. Mansour University of Kentucky, Lexington, USA

Adam Friedman Albert Einstein College of Medicine, Bronx, New York, USA

Eric R. Blough Marshall University, Huntington, West Virginia, USA

Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects.

This book gives an overview of aspects of nanomedicine to help readers design and develop novel drug delivery systems and devices that build on nanoscale technologies. Contributors explore the use of nanoparticles in inhalation aerosols, nanodermatology, wound healing, bioimaging, anticancer drug delivery, ocular drug delivery, and more. They also discuss nanotoxicity and safety studies.

Catalog no. K14612, June 2013, 469 pp.

ISBN: 978-1-4665-0616-9, $159.95 / £99.00 Also available as an eBook

Biofunctional Surface Engineering

Nanotechnology for the Delivery of Therapeutic Nucleic Acids

Edited by

Edited by

Martin Scholz

Dan Peer

LEUKOCARE AG, Munich, Germany

Tel Aviv University, Israel

The lack of effective sterilization techniques for biologics has spawned discussions about the reduction of regulatory requirements which might impose significant safety risks. On the other hand, novel and safe technologies enable the coupling, stabilization, and protection of effector molecules in a way that allows terminal sterilization without loss of function. This book provides a comprehensive overview on the state of the art and the future of biofunctional surface engineering.

Written by world experts in the field of nanotechnology for nucleic acid (NA) delivery, the authors explore the state of the art in delivery strategies using lipids, polymers, chemical conjugates, NA aptamers, and proteins. They strongly emphasize issues and aspects that are of essence to the pharmaceutical industry working in areas such as stability, general toxicity, immune-toxicity, pharmacokinetics, and the efficacy and validation of new drug targets in vivo by using unique approaches based on exquisite nanotechnology strategies.

Catalog no. N10827, February 2014, 344 pp.

ISBN: 978-981-4411-60-8, $149.95 / £95.00 Also available as an eBook

Catalog no. N10808, March 2013, 240 pp.

ISBN: 978-981-4411-04-2, $149.95 / £95.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Biomaterials Education A Laboratory Course in Biomaterials

Regenerative Engineering Edited by

Cato T. Laurencin and Yusuf Khan

Wujing Xian

University of Connecticut Health Center, Farmington, USA

Regenerative engineering is the intersection of regenerative medicine and tissue engineering. Regenerative medicine focuses on the biological aspects of tissue regeneration, while tissue engineering focuses on the integration of materials science and life sciences. This book integrates these two areas, presenting each concept in the framework of regenerative engineering.

Through the combination of fundamental lecturebased teaching and problem-based learning approaches, this textbook develops students into future researchers capable of completing the translation of their work from the bench top to the bedside.

• Provides a brief overview of the regeneration and repair of diverse tissue types • Synergizes the fields of tissue engineering, materials science, and regenerative medicine

University of Illinois at Urbana-Champaign, USA

A teaching tool for instructors in biomaterials and bioengineering, this volume is a comprehensive laboratory textbook. It introduces laboratory skills, data analysis, problem solving, and scientific writing. It integrates a variety of principles that include materials science, chemistry, biochemistry, molecular and cell biology, and engineering. Providing detailed descriptions, explanations, and illustrations of experiments, the text includes a series of questions and answers at the end of each chapter to clarify concepts.

It presents detailed, step-by-step descriptions of lab procedures and explanations for the underlying principles.

Catalog no. 75829, June 2009, 216 pp., Soft Cover ISBN: 978-1-4200-7582-3, $67.95 / £43.99 Also available as an eBook

• Includes examples, case studies, and extensive references

Selected Contents:

An Introduction to Biomaterials

Regenerative Engineering: The Future of Medicine Cell Biology Stem Cells and Tissue Regeneration Introduction to Materials Science Biomaterials In Vitro Assessment of Cell–Biomaterial Interactions Host Response to Biomaterials and Its Implications in Regenerative Engineering Organ Regenerative Engineering: Cell Sources, Considerations, and Strategies Cardiovascular Regenerative Engineering Bone Regenerative Engineering Engineering Tissue-to-Tissue Interfaces Neural Regenerative Engineering Ligament Regenerative Engineering Skeletal Muscle Regenerative Engineering Engineering Limb Regeneration: Lessons from Animals That Can Regenerate. Index

The second edition of this popular text includes nine new chapters that provide a comprehensive and up-todate educational framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living system into which it is implanted. The book explains in vitro and in vivo testing paradigms and provides numerous examples in the chapters on experimental design, laboratory assays, and animal models.

Catalog no. K10724, June 2013, 435 pp.

ISBN: 978-1-4398-1412-3, $99.95 / £63.99 Also available as an eBook

Catalog no. K10637, November 2011, 644 pp.

ISBN: 978-1-4398-1256-3, $119.95 / £49.99 Also available as an eBook

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Second Edition Edited by

Jeffrey O. Hollinger Carnegie Mellon University, Pittsburgh, Pennsylvania, USA Series: Biomedical Engineering

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Biomaterials Education Ultrasonic and Electromagnetic NDE for Structure and Material Characterization Engineering and Biomedical Applications Edited by

Tribikram Kundu The University of Arizona, Tucson, USA

Most books on NDE focus either on the theoretical background or on advanced applications. Bridging the gap, this book brings together the principles, equations, and applications of ultrasonic and electromagnetic NDE in a single, authoritative resource. It begins with the fundamentals of mechanics and electromagnetic theory, derives the basic equations, and then, step by step, covers state-of-the-art topics and applications. These include structural health monitoring, acoustic microscopy, terahertz imaging, and more. This book appeals to students as well as practicing engineers and researchers.

Catalog no. K11655, June 2012, 890 pp.

ISBN: 978-1-4398-3663-7, $149.95 / £95.00 Also available as an eBook

Learning Bio-MicroNanotechnology Mel I. Mendelson This book is designed for students who lack a cross-disciplinary background and knowledge of micro- and nano-technology. It contains many examples, questions, and problems divided into three hierarchical learning skills: understanding, analyzing, and evaluating the concepts. The author attempts to break down the boundaries between biology, chemistry, physics, engineering and ethics. He accomplishes this by co-mingling the vocabulary and concepts of these disciplines around bio-applications. This new text leans heavily towards biological and biomedical applications and includes a comprehensive chapter on ethics.

Catalog no. 82035, January 2013, 611 pp.

ISBN: 978-1-4200-8203-6, $89.95 / £57.99 Also available as an eBook

A Laboratory Course in Tissue Engineering Melissa Kurtis Micou University of California, San Diego, USA

Dawn Kilkenny University of Toronto, Ontario, Canada

This book fills the need for a hands-on lab manual for tissue engineering instruction. Providing more than a semester’s worth of activities, it contains 15 standalone experiments based on both classic and modern approaches. Experiments encompass a set of widely applicable techniques: cell culture, microscopy, histology, immunohistochemistry, mechanical testing, soft lithography, and common biochemical assays. The experiments emphasize engineering analysis, mathematical modeling, and statistical experimental design.

To minimize lab costs, experiments use equipment commonly found in labs equipped for tissue culture.

Catalog no. K13694, August 2012, 304 pp.

Soft Cover, ISBN: 978-1-4398-7893-4 $59.95 / £38.99 Also available as an eBook

The Textbook of Nanoneuroscience and Nanoneurosurgery Edited by

Babak Kateb Cedars Sinai Medical Center, West Hollywood, California, USA

John D. Heiss National Institutes of Health, Bethesda, Maryland, USA

Providing a state-of-the-art review of this quickly evolving field, the groundbreaking volume presents current information about nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology. This text focuses on the educational gap across different disciplines, emphasizing the importance of integrating nanotechnology into clinical practice. The contributors review currently available nanoplatforms developed for cancer imaging, drug delivery, and therapeutics for neurological disorders. They also address regulatory guidelines and safety issues.

Catalog no. K12237, July 2013, 602 pp.

ISBN: 978-1-4398-4941-5, $299.95 / £191.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Biomaterials Education Biomaterials

Introduction to BioMEMS

A Nano Approach

Albert Folch

Seeram Ramakrishna

University of Washington, Seattle, USA

National University of Singapore

Murugan Ramalingam

This classroom-tested book— in color throughout —covers the whole breadth of this dynamic field, including classical microfabrication, microfluidics, tissue engineering, cellbased and noncell-based devices, and implantable systems. It gives readers a real sense of how the field has grown by providing historical perspectives and covering the state of the art. The text contains problem sets, design challenges, key references, and over 400 color figures, most of which are from the original researchers. Downloadable PowerPoint slides are available for instructors.

University of Strasbourg, France

Catalog no. K10966, August 2012, 528 pp.

ISBN: 978-1-4398-1839-8, $89.95 / £57.99 Also available as an eBook

T.S. Sampath Kumar Indian Institute of Technology, Madras

Winston O. Soboyejo Princeton University, New Jersey, USA

This book examines basic concepts, various processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications. It spans their historical development and reviews recent advances in the field. It describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. Presenting illustrative examples and a variety of applications, this text offers a solid framework for understanding present and future trends of biomaterials in human health care systems.

Catalog no. 47817, June 2010, 372 pp.

ISBN: 978-1-4200-4781-3, $104.95 / £73.99 Also available as an eBook

New!

Robotic Surgery

BioMEMS Science and Engineering Perspectives

Smart Materials, Robotic Structures, and Artificial Muscles

Simona Badilescu and Muthukumaran Packirisamy

Mohsen Shahinpoor and Siavash Gheshmi

Concordia University, Montreal, Quebec, Canada

This text focuses on robotic surgery and biomimetic artificial muscles and their possible engineering, industrial, medical, and science applications. It presents the fundamentals of surgical robots, including the design of their geometrical configurations, kinematics, dynamics, and control. It also describes the designs of ophthalmic surgical robots and general laparoscopic surgical robots as well as applications of materials and systems that can be manufactured or fabricated to act like biomimetic artificial muscles, sensors, and actuators.

University of Maine, Orono, USA

Covering often overlooked areas in the field of bioMEMS, this volume spans topics associated with biomolecules and complex biological entities, as well as subjects directly linked to the design, fabrication, and characterization of devices. Unlike other references, this text aids in the fundamental physicochemical understanding of biological processes relevant to the performance of various biosensing devices. Useful for upper-level undergraduate and graduate students enrolled in engineering programs, the book includes problems in each chapter, in addition to case studies that provide real-life examples.

Catalog no. N11018, June 2014, 300 pp.

ISBN: 978-981-4316-23-1, $179.95 / £114.00

Catalog no. K10877, April 2011, 368 pp.

ISBN: 978-1-4398-1699-8, $104.95 / £66.99 Also available as an eBook

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Medical Devices Quality of Life Technology Handbook

Design Controls for the Medical Device Industry

Edited by

Second Edition

Richard Schulz

Marie B. Teixeira

University of Pittsburgh, Pennsylvania, USA

QA/RA Compliance Connection, Inc., Odessa, Florida, USA

Series: Rehabilitation Science in Practice Series

This second edition of a bestseller provides a comprehensive review of design control requirements, as well as techniques to ensure your design control program follows current industry practice. The text assists you in developing a program that not only satisfies US FDA Quality System Regulation (QSR) and ISO 9001 and 13485 standards, but also meets third-party auditor/investigator expectations. The author’s continual participation in FDA QSR inspections and Notified Body ISO audits is reflected in practical updates to all chapters and appendices of the book.

A collaboration between leading scientists, practitioners, and researchers at Carnegie Mellon University and the University of Pittsburgh, this book describes the development, evaluation, adoption, and commercialization of quality of life technologies. It takes an interdisciplinary team approach to the process of technology development for disabled and older persons and discusses the state of the art and future directions of technologies. It provides direction on how to identify user needs and preferences, engage end-users in the design and development process, and evaluate and commercialize the technologies.

• Introduces an innovative model that conceptualizes QoL systems in terms of functional domain, adaptability, user involvement, and systems intelligence • Provides detailed how-to guidance for each step of the technology development-commercialization process in the field • Includes illustrations, figures, and tables to clarify concepts

Selected Contents: Introduction and Conceptual Foundations: Who Can Benefit from Quality of Life Technology?

Facilitators and Barriers to Technology Uptake: Individual End-User Perspectives. Facilitators and Barriers to Technology Uptake: Organizational and Societal Perspectives. Design, Development, and Evaluation: Assessing Needs, Preferences, and Attitudes Using Survey Methods. Design and Development Process. Universal Design for Quality of Life Technologies. Fostering Teamwork and Community Partnerships. Evaluating Quality of Life Technologies. Core Technologies and Their Application: Vision-Based Sensing Approaches to QoLT. HERB: Personal Assistive Mobile Manipulator in the Home. Architecture and Applications of Virtual Coaches. Non-Wearable In-Home Sensing for Early Detection of Health Changes. Quality of Life Technologies in Supporting Family Caregivers.

Transforming Education and the Market Place: Developing Future Generations of QoLT Researchers through Education, Outreach, and Diversity Initiatives.

Innovation, Commercialization, and Start-Ups. Catalog no. K14561, October 2012, 334 pp.

ISBN: 978-1-4665-0534-6, $139.95 / £89.00 Also available as an eBook

• Offers a major revision of a bestselling reference, with revised and expanded chapters • Includes a new chapter on risk management, as well as updated appendices • Delivers even more practical advice, examples, and explanations • Covers current expectations and thinking in regard to design control compliance • Supplies extensive new references at the end of each chapter to enhance further study

Selected Contents: Preface Author Biography Introduction Device Classification Overview of Design Controls Design and Development Planning Design Inputs Part I Design Inputs Part II Design Outputs Design Review Design Verification Risk Management Design Validation Biocompatibility Design Transfer Design Change Design History File Quality System Inspection Technique References Appendices Index Catalog no. K14470, November 2013, 205 pp.

ISBN: 978-1-4665-0354-0, $169.95 / £108.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Medical Devices Medical Equipment Management

Reliable Design of Medical Devices

Keith Willson

Third Edition

Imperial College London, UK

Richard C. Fries

Keith Ison

ISORel, Inc., Fitchburg, Wisconsin, USA

Head of Medical Physics, Guy's and St Thomas' NHS Foundation Trust, UK

Slavik Tabakov Consultant Medical Physicist, Department of Medical Physics, King's College Hospital Foundation Trust and Programme Director, Medical Engineering and Physics, King's College London, UK Series: Series in Medical Physics and Biomedical Engineering

As medical technology in clinical care becomes more complex, clinical professionals and support staff must know how to keep patients safe and equipment working in the clinical environment. Accessible to all healthcare professionals and managers, this book presents an integrated approach to managing medical equipment in healthcare organizations. It explains the underlying principles and requirements and raises awareness of what needs to be done and what questions to ask. The book also provides practical advice and refers readers to appropriate legislation and guidelines.

• Applies risk management approaches to medical equipment management/healthcare technology management, guiding readers on how to stay within the law and efficiently purchase medical equipment • Provides practical advice and examples of the medical equipment lifecycle, including servicing and maintenance • Describes organizational structures and political processes relevant to medical equipment management policy and its implementation in a healthcare organization • Discusses monitoring and improving the performance of equipment service organizations • Includes reference sources to regulatory agencies, international standards, societies, and other organizations • Introduces electrical safety for medical equipment at a level suitable for students and healthcare professionals

Selected Contents: Introduction. Risk, Regulation and Governance.

The Equipment Management Process. Specialized Content. Appendices: Illustrative Examples.

Catalog no. K10003, December 2013, 344 pp.

ISBN: 978-1-4200-9958-4, $79.95 / £49.99 Also available as an eBook

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Following in the footsteps of the bestselling second edition, this book shows you how to improve reliability in the design of advanced medical devices. The organization of the book now mirrors the typical product development process, from the concept, feasibility, and design phases through to verification and validation, design transfer and manufacturing, and field activity.

Updated throughout, it reflects recent changes in the medical device field. This practical, hands-on book guides you in preparing, designing, and testing medical devices more effectively.

• Incorporates reliability into the whole design and development process • Explains the design process from conception to field monitoring • Discusses regulations and standards as well as human factors • Emphasizes safety and risk analysis • Includes numerous illustrations, tables, sample forms, checklists of deliverables, references, and useful appendices

Selected Contents: The Basics of Reliability: Reliability. The Concept of Failure. The Product Design and Development Process. The Concept Phase: Defining the Device.

Safety and Risk Management. Documents and Deliverables. The Feasibility Phase: The FDA. The Medical Devices Directives. Important Medical Device Standards. Human Factors. Requirements Engineering.

Liability. Intellectual Property. The Project Team. The Reliability Goal and Plan. Documents and Deliverables.

The Design Phase: Hardware Design. Hardware Risk Analysis. Design and Project Metrics. Design for Six Sigma. Software Design. Software Coding. Software Risk Analysis. Software Metrics. Documents and Deliverables. Verification and Validation: The Basis and Types of Testing. Hardware Verification and Validation. Hardware Data Analysis. Software Verification and Validation. Software Data Analysis.

Documents and Deliverables. Design Transfer and Manufacturing: Transfer to Manufacturing. Hardware Manufacturing. Software Manufacturing.

Configuration Management. Documents and Deliverables. Field Activity: Analysis of Field Data.

Monitored Activity. Appendices. Index.

Catalog no. K14218, September 2012, 501 pp.

ISBN: 978-1-4398-9491-0, $179.95 / £114.00 Also available as an eBook

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CJN01_5.5x8.5_MC_Temp 4/30/14 12:37 PM Page 27

Medical Devices New!

New!

Design of Biomedical Devices and Systems

Preventing Medical Device Recalls

Third Edition

Based on the author’s extensive experience in the medical devices and manufacturing engineering industries, this book can save medical device companies millions of dollars by preventing many deaths and costly recalls. It is the first text to show how to control safety risks, starting from specifications to safely retiring the products without harm to the environment. The book covers medical device requirements, preventing recalls during specification writing, risk assessment and management, preventing recalls during design and development, and much more.

Paul H. King, Richard C. Fries, and Arthur T. Johnson Intended for a senior design course in biomedical/bioengineering, this book offers a comprehensive approach to the design methodologies of modern medical devices. A substantial revision of a solid text, the third edition contains new coverage on clinical trials, provides additional mathematical modeling tools, includes information on sterilization and bioprocessing, devotes more instruction to integrating medical and biological considerations with engineering, and features updates to all chapters as well as new problems, examples, and case studies throughout.

Catalog no. K16421, August 2014, 400 pp.

ISBN: 978-1-4665-6913-3, $129.95 / £82.00 Also available as an eBook

New!

Mobile Point-ofCare Monitors and Diagnostic Device Design Edited by

Walter Karlen Series: Devices, Circuits, and Systems, Vol. 31

Diagnostics at the point of care is a disruptive technology that will change how health care is delivered.

Connecting mobile health and point-of-care technology, this book gives an overview of available technologies for mobile point-of-care systems. It also offers insights on state-of-the-art technology, research, and methods for designing personal diagnostic and ambulatory healthcare devices. Topics include portable diagnostics devices and sensors, lab-on-chip systems, energy and power efficient solutions, computer vision and signal processing for real-time diagnostics, user interface design, and quality control and regulatory approval challenges.

Catalog no. K20399, August 2014, 168 pp.

ISBN: 978-1-4665-8929-2, $99.95 / £63.99 Also available as an eBook

Dev Raheja

Catalog no. K16376, July 2014, 232 pp.

ISBN: 978-1-4665-6822-8, $99.95 / £63.99 Also available as an eBook

Computer Systems Experiences of Users with and Without Disabilities An Evaluation Guide for Professionals Simone Borsci Masaaki Kurosu Stefano Federici and Maria Laura Mele University of Perugia, Italy

Series: Rehabilitation Science in Practice Series This book provides the necessary tools for the evaluation of the interaction between the user who is disabled and the computer system that was designed to assist that person. The book creates an evaluation process that is able to assess the user's satisfaction with a developed system. Presenting a new theoretical perspective in the human computer interaction evaluation of disabled persons, it takes into account all of the individuals involved in the evaluation process.

Catalog no. K14823, November 2013, 295 pp.

ISBN: 978-1-4665-1113-2, $149.95 / £95.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Medical Devices The Medical Device R&D Handbook Second Edition Edited by

Theodore R. Kucklick TRKD Medical Devices, Los Gatos, California, USA

This reference explains the basics on how to prototype and develop a medical device. It discusses the basics of plastics, adhesives, medical needles, and rapid prototyping as well as tips and tools to save time and money. This updated and expanded second edition includes practical advice, information on intellectual property management, and insightful interviews from key opinion leaders and pioneers in the field.

Extensive references at the end of each chapter enhance additional study.

Catalog no. K10598, December 2012, 510 pp.

ISBN: 978-1-4398-1189-4, $169.95 / £108.00 Also available as an eBook

Devices for Mobility and Manipulation for People with Reduced Abilities Teodiano Freire Bastos-Filho Federal University of Espirito Santo, Vitoria, Brazil

Dinesh Kumar and Sridhar Poosapadi Arjunan RMIT University, Melbourne, Australia Series: Rehabilitation Science in Practice Series

This volume provides insight into current research trends and discusses technologies that are under development. Each chapter covers one specific technology, starting with a general introduction, followed by technical details and an assessment from the user viewpoint—including the user benefits, user suitability, cost, reliability, and required infrastructure. Each chapter also provides illustrations or photographs of the devices, making it accessible to the lay person as well as clinical audiences. The book also identifies shortcomings, current research related to the technology, and possible development opportunities.

Catalog no. K20293, April 2014 ISBN: 978-1-4665-8645-1, $139.95 / £89.00 Also available as an eBook

Biomedical Technology and Devices

ISO 13485

Second Edition

A Complete Guide to Quality Management in the Medical Device Industry

Edited by

James E. Moore Jr Duncan J. Maitland

Itay Abuhav

Series: Handbook Series for Mechanical Engineering

Hinterforst, Switzerland

Fully revised since its original publication, this reference illuminates the equipment, devices, and techniques used in modern medicine to diagnose, treat, and monitor human illnesses. With topics ranging from basic procedures like blood pressure measurements to cutting-edge imaging equipment, biological tests, and genetic engineering, the book is organized to navigate smoothly from simple procedures and concepts to more sophisticated and complex ones.

Each section contains a description of the technique, its technical considerations, and its use according to its applications and relevant body systems.

The United States and European Union now require the ISO 13485 Standard certification for medical device manufacturers. Written by an experienced industry professional, this practical book provides a complete guide to the ISO 13485 Standard certification for medical device manufacturing in terms of quality control. It covers all the requirements of ISO 13485 and offers a step-by-step comparison between the ISO 13485 and ISO 9001, enabling a sound understanding of these new procedures.

Catalog no. K12728, June 2013, 820 pp.

ISBN: 978-1-4398-5959-9, $189.95 / £121.00 Also available as an eBook

Catalog no. K12946, October 2011, 374 pp.

ISBN: 978-1-4398-6611-5, $139.95 / £89.00 Also available as an eBook

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Medical Devices Usability Testing of Medical Devices Michael E. Wiklund, P.E., Jonathan Kendler and Allison Y. Strochlic Wiklund Research & Design, Inc., Concord, Massachusetts, USA

Informative, practical, and engaging, this handbook covers how to conduct usability tests of medical devices. Recognizing that the intended readers are busy and disinclined to read lengthy textbooks, this book has been carefully designed to be concise and visual, allowing readers to jump from one section to another as needed. The book provides a general understanding of usability testing and reviews key concepts. It highlights the challenges of validating that protects against dangerous errors that could lead to patient injury and death.

Catalog no. K10595, December 2010, 412 pp.

ISBN: 978-1-4398-1183-2, $76.95 / £48.99 Also available as an eBook

Handbook of Human Factors in Medical Device Design Edited by

Matthew Bret Weinger, Michael E. Wiklund, and Daryle Jean Gardner-Bonneau Promoting the user-centric design of safe, effective, and usable medical devices, this book offers information on general and specific design guidelines. A comprehensive guide, it explores fundamental topics, general human factors principles, the design of specific interface elements, specific types of devices, and devices for particular use environments. It also includes expanded discussions of design issues, product design case studies, and supporting examples, tables, figures, and illustrations. The text contains cross references that make finding information quick and easy.

Catalog no. ER562X, December 2010, 844 pp.

ISBN: 978-0-8058-5627-9, $145.95 / £93.00 Also available as an eBook

Designing Usability into Medical Products

Handbook of Medical Device Regulatory Affairs in Asia

Michael E. Wiklund

Edited by

Wiklund Research & Design, Inc., Concord, Massachusetts, USA

Jack Wong

Stephen B. Wilcox Design Science, Philadelphia, Pennsylvania, USA

This book covers the essential processes and specific techniques necessary to produce safe, effective, usable, and appealing medical systems and products.

Written by experts on user-centered research, design, and evaluation, the book provides a range of alternative approaches. It explores how to make medical devices safe and effective by involving users in the design process. They discuss specific design and evaluation methods and tools, present case studies of user-friendly medical technologies and corporate human factors programs, and supply related resources for medical design professionals.

Catalog no. 2843, February 2005, 376 pp.

ISBN: 978-0-8493-2843-5, $146.95 / £94.00 Also available as an eBook

Asia Regulatory Professional Association, Kwun Tong, Kowloon, Hong Kong

Raymond Tong Kaiyu Hong Kong Polytechnic University, Hung Hom, Kowloon

With a focus on Asian countries, this handbook covers medical device regulatory systems in different regions, ISO standards for medical devices, clinical trial and regulatory requirements, and documentation for application. Each chapter provides background materials relevant to the particular area to provide readers with a better understanding of regulatory affairs. With contributions from authors working with regulatory bodies around the world, the handbook explains the basics of the Asian market and how to access it. It also guides product developers through the global regulatory environment.

Catalog no. N10745, March 2013, 616 pp.

ISBN: 978-981-4411-21-9, $149.95 / £95.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Industry Applications New!

Process Safety Practical Applications for Safe and Reliable Operations James A. Klein Bruce K. Vaughen This book covers the basics of process safety that are applicable to plant engineering in a targeted, practical way.

It assists plant engineers working with process safety systems that impact their daily work and helps them contribute to plant safety, operations, and reliability.

Topics include understanding process hazards and events, the design and operation of your facility, what can go wrong and how to respond, making equipment and facility changes safely, maintaining safe and reliable equipment, and monitoring plant safety performance.

• Covers the basic, practical application of process safety for plant engineers • Employs an accessible writing style focused on practical use rather than theory • Focuses on the general plant engineer rather than the specialist engineer • Offers a practical introduction for engineering students with an interest in plant careers • Includes practical examples, case studies, and tools to help plant engineers work more safely and productively Catalog no. K16099, November 2014, 400 pp.

ISBN: 978-1-4665-6542-5, $159.95 / £99.00 Also available as an eBook

New!

Measurement, Instrumentation, and Sensors Handbook, Second Edition Spatial, Mechanical, Thermal, and Radiation Measurement Edited by

John G. Webster University of Wisconsin - Madison, USA

Halit Eren Curtin University, Bentley, Australia

A concise and useful reference for engineers, designers, scientists, students, academia, and industry professionals, this text describes the implementation of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences. It contains contributions from field experts, new chapters, and updates to all 96 existing chapters. It covers instrumentation and measurement concepts, spatial and mechanical variables, displacement, acoustics, flow and spot velocity, radiation, wireless instrumentation, and control and human factors.

• Describes the use of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences • Presents information organized according to measurement problem • Discusses processing systems, automatic data acquisition, reduction and analysis, operation characteristics, accuracy, errors, calibrations, and the incorporation of standards for control purposes • Contains contributions from field experts, new chapters, and updates to all 96 existing chapters • Covers instrumentation and measurement concepts, spatial and mechanical variables, displacement, acoustics, flow and spot velocity, radiation, wireless instrumentation, and control and human factors

Selected Contents: Preface. Acknowledgments. Editors. Contributors.

Instrumentation and Measurement Concepts. Spatial Variables. Displacement. Mechanical Variables.

Acoustics. Flow and Spot Velocity. Thermal and Temperature Measurement. Radiation. Wireless Techniques and Instrumentation. Control and Human Factors. Appendix: Units and Conversions. Index.

Catalog no. K12208, January 2014, 1640 pp.

ISBN: 978-1-4398-4888-3, $149.95 / £95.00 Also available as an eBook

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Industry Applications What Every Engineer Should Know About Cyber Security and Digital Forensics Joanna F. DeFranco The Pennsylvania State University, Malvern, USA Series: What Every Engineer Should Know

Designed for the non-security professional, this volume is an overview of cyber security and digital forensics. Topics include network and personal data security, the information security common body of knowledge, cloud and mobile computing, preparing for and responding to an incident, evidence handling, security compliance, law, and more. By mastering the principles in this volume, engineering professionals will not only better understand how to mitigate the risk of security incidents and keep their data secure, but also understand how to break into this expanding field.

Catalog no. K16045, October 2013, 168 pp.

Soft Cover, ISBN: 978-1-4665-6452-7 $59.95 / £38.99 Also available as an eBook

Biomaterials Fabrication and Processing Handbook Edited by

Paul K. Chu City University of Hong Kong, Kowloon

Xuanyong Liu Shanghai Institute of Ceramics, China

Comprehensive in scope, this volume focuses on a variety of production and processing aspects of the latest biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials, such as hard tissue, blood contacting, and soft tissue. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bio-MEMS. This book provides detailed, practical guidance on producing biomaterials and employing them in biomedicine.

Technical Writing A Practical Guide for Engineers and Scientists Phillip A. Laplante The Pennsylvania State University, Malvern, USA Series: What Every Engineer Should Know

Written by a renowned engineer and widely published technical author, this guide enables readers to write, edit, and publish materials of a technical nature, including books, articles, reports, and electronic media. Complementing the traditional writer’s reference manuals and other books on technical writing, it helps readers understand the practical considerations in writing technical content. Drawing on his own experiences, the author presents many first-hand examples of writing, editing, and publishing technical materials. These examples illustrate how a publication originated as well as various challenges and solutions.

Catalog no. K11106, July 2011, 250 pp., Soft Cover ISBN: 978-1-4398-2085-8, $41.95 / £26.99 Also available as an eBook

Contracts for Engineers Intellectual Property, Standards, and Ethics Robert D. Hunter Robert D. Hunter Associates, Austin, Texas, USA

Engineers encounter various forms of contracts at nearly every turn in their careers. This book enhances their ability to communicate contractual issues to lawyers and then better understand the consequent legal advice they receive. The text introduces the related subjects of intellectual property and standards. The author also addresses the role of ethics which has been emphasized in response to the collapse of Boston’s Big Dig, the oil spill in the Gulf of Mexico, and the coal mine accident that resulted in the many deaths.

Catalog no. K12434, September 2011, 368 pp.

ISBN: 978-1-4398-5286-6, $72.95 / £46.99 Also available as an eBook

Catalog no. 7973, March 2008, 720 pp.

ISBN: 978-0-8493-7973-4, $179.95 / £115.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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