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CONTENTS Biosignals and Systems............................................3 Biomechanics ..........................................................6 BioMEMS, BioNEMS, and Biomaterials ..................8 Biomedical Imaging ..............................................13 Page 3
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Biotechnology ......................................................18 General Textbooks ................................................22
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Biosignals and Systems Bestseller!
Basic Transport Phenomena in Biomedical Engineering Third Edition Ronald L. Fournier University of Toledo, Ohio, USA
Bringing together fundamental engineering and life science principles, this highly accessible text provides a focused coverage of key momentum and mass transport concepts in biomedical engineering. It offers a basic review of units and dimensions, material balances, and problem-solving tips, and emphasizes those chemical and physical transport processes that have applications in the development of artificial and bioartificial organs, controlled drug delivery systems, and tissue engineering. The book also includes a discussion of thermodynamic concepts and covers topics such as body fluids, osmosis and membrane filtration, physical and flow properties of blood, solute and oxygen transport, and pharmacokinetic analysis. It concludes with the application of these principles to extracorporeal devices as well as tissue engineering and bioartificial organs. Designed for the beginning student, the book provides a quantitative understanding of the underlying physical, chemical, and biological phenomena involved. It offers mathematical models using the “shell balance” or compartmental approaches, along with numerous examples and end-of-chapter problems based on these mathematical models. In many cases these models are compared with actual experimental data. Encouraging students to work examples with the mathematical software package of their choice, this text provides them the opportunity to explore various aspects of the solution on their own, or apply these techniques as starting points for the solution to their own problems.
Selected Contents: Introduction. A Review of Thermodynamic Concepts. Physical Properties of the Body Fluids and the Cell Membrane. The Physical and Flow Properties of Blood. Solute Transport in Biological Systems. Pharmacokinetic Analysis. Extracorporeal Devices. Tissue Engineering. Bioartificial Organs. Index. Catalog no. K11304, August 2011, 483 pp. ISBN: 978-1-4398-2670-6, $109.95 / £55.99 Also available as an eBook
Systems Biology Mathematical Modeling and Model Analysis Andreas Kremling Technical University Munich, Germany
Series: Chapman & Hall/CRC Mathematical and Computational Biology
“Computational modeling of biological circuits, networks, and pathways is one of the most exciting areas in biology today, and Andreas Kremling's Systems Biology: Mathematical Modeling and Model Analysis is a meticulous and far-reaching treatment of this critically important subject. This book clearly aims to be comprehensive without sacrificing depth, and the result is an exhaustive survey of modeling approaches. Each chapter is thoughtfully crafted to draw in novices to the field while still engaging experts. Additionally, a number of welldesigned exercises complement each chapter. I found the sections on model analysis and control theory particularly useful and relevant.” —Markus Covert, Stanford University
Drawing on the latest research in the field, this text presents various methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about cellular systems. It also explores how the models are systematically applied in biotechnology. The book includes many analytical and numerical examples as well as exercises and a bibliography at the end of each chapter. MATLAB® code is available on the book’s CRC Press web page.
Selected Contents: Fundamentals: Introduction. Biological Basics. Fundamentals of Mathematical Modeling. Model Calibration and Experimental Design. Modeling of Cellular Processes: Enzymatic Conversion. Polymerization Processes. Signal Transduction and Genetically Regulated Systems. Analysis of Modules and Motifs: General Methods of Model Analysis. Aspects of Control Theory. Motifs in Cellular Networks. Analysis of Cellular Networks: Metabolic Engineering. Topological Characteristics. Appendix. Index. Catalog no. K16367, November 2013, 379 pp. ISBN: 978-1-4665-6789-4, $79.95 / £49.99 Also available as an eBook
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Biosignals and Systems Introduction to Biomedical Engineering Technology Second Edition Laurence Street Rosedale, British Colombia, Canada
Medical devices are often complex, but while there are differences in design from one manufacturer to another, the principles of operation and the physiological and anatomical characteristics on which they operate are universal. This book explains the uses and applications of medical technology as well as the principles of medical equipment management to familiarize readers with their prospective work environment. Written by an experienced biomedical engineering technologist, the book describes technological devices, tools, and test equipment used in today’s health care arena. Photographs of representative equipment as well as the technical, physiological, and anatomical basis for their function is detailed for a wide range of biomedical devices—from defibrillators to electrosurgery units. Also discussed are the locations where the equipment is commonly found in hospitals. Thoroughly revised and updated, this second edition covers a wider range of devices and includes an expanded section on equipment management. The author’s practical approach and organization, outlining everyday functions and applications of the medical devices, prepares readers for situations they will encounter on the job. Appendices supply useful information such as normal medical values, a list of regulatory bodies, Internet resources, and information on training programs. The revised second edition includes more examples and illustrations as well as end-of-chapter questions to test the reader’s understanding. The book also contains more than 360 illustrations.
Selected Contents:
Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation Second Edition Robert B. Northrop University of Connecticut, Storrs, USA
Series: Biomedical Engineering
This book helps biomedical engineers understand and design signal conditioning systems using analog integrated circuits. It explains the electronic components and subsystems—the “building blocks”—that are used in ECG, EEG, EMG, ERG, tomographic images, biochemical spectrograms, and other crucial medical applications. This updated second edition features a glossary, new end-of-chapter problems, and three new chapters that address wireless patient monitoring using UHF telemetry, power amplifiers and their applications to biomedical instruments, and RFID, GPS, and ultrasonic tags used in ecological research. The book provides end-of-chapter problems as well as examples that emphasize biomedical electronic applications. Catalog no. K12982, March 2012, 578 pp. ISBN: 978-1-4398-6669-6, $125.95 / £81.00 Also available as an eBook
New!
Ambient Diagnostics Yang Cai Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
Introduction. Diagnostic Devices: Part One, Part Two, and Part Three. Diagnostic Imaging. Treatment Devices: Part One, Part Two, and Part Three. Biomedical Engineering Technologist (BMET) Work. Testers and Tools. Batteries, Radiation, and Computers. Technology Management. Appendices: Normal Values, Regulations and Standards, Biomedical Engineering Technology Programs in the United States and Canada, Biomedical Associations, Devices and Manufacturers, Test Equipment Manufacturers, Bibliography and Internet Resources.
This text addresses innovative methods for discovering patterns from affordable devices, such as mobile phones, watches, cameras, and game interfaces to interpret multimedia data for personal health monitoring and diagnosis. This is the first comprehensive textbook for studying multidisciplinary innovations in affordable health care—from sensory fusion to pattern detection to classification. The book includes 171 exercise problems and 45 case studies.
Catalog no. K12781, October 2011, 391 pp. ISBN: 978-1-4398-6058-8, $98.95 / £62.99
Catalog no. K14779, July 2014, c. 394 pp. ISBN: 978-1-4665-1041-8, $99.95 / £63.99
Also available as an eBook
Also available as an eBook
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Biosignals and Systems Biomedical Engineering Principles Second Edition
Signals and Systems Analysis In Biomedical Engineering
Arthur B. Ritter, Vikki Hazelwood, Antonio Valdevit, and Alfred N. Ascione
Second Edition
Praise for the Previous Edition:
Series: Biomedical Engineering
“For practicing engineers without biomedical engineering background, the book provides an excellent resource to explain the many intricacies of biomedical engineering and provides sufficient background material to make the subject understandable.” —Richard C. Fries, PE, CRE, Baxter Healthcare, Inc., in IEEE Engineering in Medicine and Biology Magazine, December 2006
“[Provides] not only an in-breadth overview on current BME fields, but also an in-depth analysis of specific selected topics that are supported by appropriate mathematical models, equations, quantitative data charts and tables.” —Biomedical Engineering Online, 2005
Integrating engineering, medicine, biology, and physics, this book clearly defines basic principles in image processing, biomechanics, modeling physiological processes, and bioelectric signal analysis to build a solid understanding of devices and designs for improved functioning of the human body. It includes cutting-edge discussions on tissue engineering, cardiovascular components, bone regrowth, and nerve regeneration. Other topics covered include technologies at the forefront of cardiac care—such as total artificial hearts, left ventricular assist devices, and stents—and issues related to minimally invasive and robotic surgery, next-generation imaging devices, and nanodevices.
Selected Contents: Introduction: Modeling of Physiological Processes. Cell Physiology and Transport. Principles and Biomedical Applications of Hemodynamics. A Systems Approach to Physiology. The Cardiovascular System. Biomedical Signal Processing. Signal Acquisition and Processing. Techniques for Physiological Signal Processing. Examples of Physiological Signal Processing. Principles of Biomechanics. Practical Applications of Biomechanics. Biomaterials. Principles of Biomedical Capstone Design. Unmet Clinical Needs. Entrepreneurship: Reasons why Most Good Designs Never Get to Market. An Engineering Solution in Search of a Biomedical Problem to Solve. Tissue Engineering. Future Trends in BME. Catalog no. K10621, May 2011, 540 pp. ISBN: 978-1-4398-1232-7, $109.95 / £69.99
Robert B. Northrop University of Connecticut, Storrs, USA
This book focuses on the mathematical tools required to analyze and describe biomedical signals and systems. Based on the author's 30 years of experience in teaching as well as his personal research on neurosensory systems, this book, now in its second edition, provides a ready source of information on the specialized mathematical techniques most useful in describing and analyzing biomedical signals. It discusses the analysis of nonlinear systems, nonlinear oscillators, and biological clocks. It also explores the mathematics of tomographic imaging, covers joint time-frequency analysis of nonstationary biomedical signals, and describes the Hilbert transform. Catalog no. K10633, March 2010, 654 pp. ISBN: 978-1-4398-1251-8, $129.95 / £77.99 Also available as an eBook
Biology for Engineers Arthur T. Johnson University of Maryland, College Park, USA
Biology is a critical application area for engineering analysis and design. Engineering students in some programs must be well versed in the fundamentals of biology as they relate to their field. This is an introductory text that minimizes unnecessary memorization of connections and classifications and instead emphasizes concepts, technology, and the utilization of living things. Emphasizing the ever-present interactions between a biological unit and its physical, chemical, and biological environments, the book provides ample instruction on the basics of physics, chemistry, mathematics, and engineering. It brings together all the concepts needed to understand the role of biology in modern technology. Catalog no. 77635, September 2010, 775 pp. ISBN: 978-1-4200-7763-6, $115.95 / £72.99 Also available as an eBook
Also available as an eBook
For more information and complete contents, visit www.crctextbooks.com
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Biomechanics Biofluid Mechanics
Fundamentals of Biomechanics
The Human Circulation, Second Edition
Ronald L. Huston
Krishnan B. Chandran, Stanley E. Rittgers, and Ajit P. Yoganathan “... the book provides a good platform in fluid mechanics prior to progressing to the physiological applications which make it an appropriate textbook for BME students.” —Professor Tim McGloughlin, Centre for Applied Biomedical Engineering Research and Department of Mechanical Aeronautical and Biomedical Engineering, University of Limerick
This classroom-tested text teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition includes improved figures, additional examples, and more problems at the end of each chapter. It also presents a new chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas.
University of Cincinnati, Ohio, USA
“This biomechanics book does indeed lay the ground for learning the fundamentals in biomechanics, which have been lacking for so many years. The book gets away from the statics concepts that are quite abundant and dominant topics in previous published biomechanics books and instead focuses on motion, dynamics, and current practical problems that are relevant to gait analysis and human joint dynamics. The examples are vivid, intuitive, [and] interesting.” —Farid Amirouche, University of Illinois at Chicago
• Reviews fluid and solid mechanics and normal cardiovascular physiology
This textbook provides a comprehensive survey of how principles of mechanics are applied to human systems and organs. After a review of terminology, a summary of human anatomy, and a presentation of anthropometric data, the text discusses methods for biomechanical analyses including essential mathematics, mechanics, and modeling techniques. It then covers tissue biomechanics, kinematics, and dynamics of human body models as well as applications such as lifting, walking, swimming, and accident victim simulation. Each chapter contains reference lists for more in-depth study and problems sets with solutions.
• Explains how to model steady and unsteady flows
Selected Contents:
• Evaluates the design and development of artificial heart valves, stent implants, and vascular grafts • Describes various approaches for modeling cardiovascular diseases and therapies • Includes end-of-chapter references and problems as well as numerous figures throughout
Selected Contents: Fluid And Solid Mechanics And Cardiovascular Physiology: Fundamentals of Fluid Mechanics. Introduction to Solid Mechanics. Cardiovascular Physiology. Biomechanics Of The Human Circulation: Rheology of Blood and Vascular Mechanics. Static and Steady Flow Models. Unsteady Flow and Nonuniform Geometric Models. Native Heart Valves. Cardiovascular Implants, Biomechanical Measurements, And Computational Simulations: Prosthetic Heart Valve Dynamics. Vascular Therapeutic Techniques. Fluid Dynamic Measurement Techniques. Computational Fluid Dynamic Analysis of the Human Circulation. Index.
Introduction. Review of Human Anatomy and Some Basic Terminology. Methods of Analysis I: Review of Vectors, Dyadics, Matrices, and Determinants. Methods of Analysis II: Forces and Force Systems. Methods of Analysis III: Mechanics of Materials. Methods of Analysis IV: Modeling of Biosystems. Tissue Biomechanics. Kinematical Preliminaries: Fundamental Equations. Kinematic Preliminaries: Inertia Force Considerations. Human Body Inertia Properties. Kinematics of Human Body Models. Kinetics of Human Body Models. Dynamics of Human Body Models. Numerical Methods. Simulations and Applications. Catalog no. K14776, April 2013, 470 pp. ISBN: 978-1-4665-1037-1, $99.95 / £63.99 Also available as an eBook
Catalog no. K12006, February 2012, 451 pp. ISBN: 978-1-4398-4516-5, $109.95 / £69.99 Also available as an eBook
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Biomechanics Biomechanics of the Upper Limbs
Biofluid Dynamics
Mechanics, Modeling and Musculoskeletal Injuries, Second Edition
Principles and Selected Applications
Andris Freivalds The Pennsylvania State University, University Park, USA
There already is a wealth of literature covering cumulative trauma disorders, medical management, and lower back problems. However, despite a spike in the number of work-related musculoskeletal disorders of the upper limbs due to an increase in the number of computer-related jobs, few if any books have focused exclusively on such disorders, until now. In its second edition, this comprehensive text is expanded to include recent findings regarding job stressors and ergonomic solutions. It provides up-todate research on the biomechanics of the upper limbs and the mechanics of neuromuscular systems. It covers risk factors for various disorders and tools used to identify their causes. The book provides numerous examples in each chapter and also features downloadable PowerPoint slides, sample exams, and other background material on a supporting website.
This comprehensive text explores: • Biomechanics of the upper limbs and the motor control system • The structure and physiology of the human musculoskeletal and neuromuscular systems • Recent research findings and solutions to various ergonomic problems
Clement Kleinstreuer North Carolina State University, Raleigh, USA
Biofluid Dynamics builds a solid understanding of medical implants and devices from a bioengineering standpoint. The text features extensive worked examples and mathematical appendices; exercises and project assignments to stimulate critical thinking and build problem-solving skills; numerous illustrations, including a 16-page color insert; computer simulations of biofluid dynamics processes and medical device operations; tools for solving basic biofluid problems; and a glossary of terms. The text can be used as a primary selection for a comprehensive course, as a two-course sequence, or as a reference for professionals in biomedical engineering and medicine. • Presents the first comprehensive textbook on biofluid dynamics • Provides extensive worked examples, homework problems, and illustrations • Contains project assignments to stimulate critical thinking and build students’ problem-solving skills • Develops the necessary tools for solving basic biofluid problems analytically, approximately, and numerically • Offers computer simulations of biofluid dynamics processes and medical device operations
• Risk factors for disorders and tools used to identify their causes
Selected Contents:
Selected Contents:
Elements of Continuum Mechanics. Biofluid Dynamics Concepts. Analyses of Arterial Diseases. Biofluid Mechanics of Organ Systems. Case Studies in Biofluid Dynamics. Appendices. Index.
Introduction to Biomechanics. Structure of the Musculoskeletal System. Neuromuscular Physiology and Motor Control. Modeling of Muscle Mechanics. Models of the Upper Limbs. Musculoskeletal Disorders and Risk Factors. Instrumentation. Job and Worksite Analysis. Hand Tools. The Office Environment.
Catalog no. 2221, April 2006, 528 pp. ISBN: 978-0-8493-2221-1, $125.95 / £82.00 Also available as an eBook
Catalog no. 91190, February 2011, 564 pp. ISBN: 978-1-4200-9119-9, $129.95 / £84.00 Also available as an eBook
For more information and complete contents, visit www.crctextbooks.com
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BioMEMS, BioNEMS, and Biomaterials Introduction to BioMEMS Albert Folch University of Washington, Seattle, USA
“Dr. Folch’s book is a monumental achievement which brings an authoritative and comprehensive account to the rapidly growing, multidisciplinary field of BioMEMS. Many working scientists and engineers as well as students will find this book fascinating.” —Mehmet Toner, Helen Andrus Benedict Professor of Bioengineering, Harvard Medical School
“With extensive citations of the current literature, explanations that really put the technology in context, clear enunciation of the motivations for miniaturization, and historical perspective, the author has made the material very accessible and clear … . I definitely recommend this textbook for bioengineering students.” —Professor Karen C. Cheung, University of British Columbia
This classroom-tested book covers the whole breadth of the field, including classical microfabrication, microfluidics, tissue engineering, implantable systems, and cell- and noncell-based devices. It gives readers a real sense of how the field has grown by providing historical perspectives and covering the state of the art. The text contains problem sets, design challenges, key references, and more than 400 color figures—most from the original researcher. Downloadable PowerPoint slides are available for instructors. • Focuses on the essentials of microfabrication • Presents in-depth coverage of the techniques of cell/protein micropatterning • Provides a thorough presentation of microfluidics
Molecular Motors in Bionanotechnology Keith Firman and James Youell University of Portsmouth, UK
Biological molecular motors provide most cells with the dynamic systems required for their day-to-day existence. Examples occur in even the simplest organism (e.g. a bacteria virus) and the range of tasks that they carry out is vast. Over the last few years there has been a large increase in the study of these motors, and it is becoming apparent that many motors will find uses in either bionanotechnology or synthetic biology. Molecular Motors in Bionanotechnology describes a wide range of molecular motors, ranging from chemical to biological motors, in a manner that updates, or reviews, both classification of the type of motor and their grouping into families. Many techniques have evolved to study and characterize molecular motors at the single-molecule level (e.g. use of molecular tweezer devices for single-molecule studies). The text introduces the reader to the concepts and benefits of these techniques. In addition, the book discusses motors that are being used or may be used in the future as part of a synthetic biology approach to building devices and sensors. • Illustrates examples of major groupings of motors • Provides a coherent review of groupings and families of molecular motors • Discusses various uses in synthetic biology and bionanotechnology Catalog no. N10568, March 2013, 212 pp. ISBN: 978-981-4267-02-1, $149.95 / £95.00 Also available as an eBook
• Discusses how BioMEMS devices can improve fluid handling • Provides a good overall vision of the evolution of implantable microdevices
Selected Contents: How Do We Make Small Things? Micropatterning of Substrates and Cells. Microfluidics. Molecular Biology on a Chip. Cell-Based Chips for Biotechnology. BioMEMS for Cell Biology. Tissue Microengineering. Implantable Microdevices. Appendix. Index. Catalog no. K10966, August 2012, 528 pp. ISBN: 978-1-4398-1839-8, $93.95 / £59.99 Also available as an eBook
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BioMEMS, BioNEMS, and Biomaterials Regenerative Engineering
An Introduction to Biomaterials
Edited by
Second Edition
Cato T. Laurencin
Edited by
University of Connecticut Health Center, Farmington, USA
Jeffrey O. Hollinger
Yusuf Khan
Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
University of Connecticut Health Center, Farmington, USA
Series: Biomedical Engineering
“The text is well written and succinct. The references are up to date. Given the background of the senior editor as an orthopaedic surgeon, clinical details are provided in most of the chapters in a highly readable manner, and this can be useful for the non-clinician user.” —The Journal of Histotechnology, March 2014
Regenerative engineering is the intersection of regenerative medicine and tissue engineering. Regenerative medicine focuses on the biological aspects of tissue regeneration via stem cells, factors, and cytokines. Tissue engineering focuses on the integration of materials science and life sciences. This book integrates these two areas, presenting each concept in the framework of regenerative engineering. Through the combination of fundamental lecture-based teaching and problem-based learning approaches, the textbook aims to develop students into future researchers capable of completing the translation of their work from the benchtop to the bedside.
Selected Contents: Regenerative Engineering: The Future of Medicine. Cell Biology. Stem Cells and Tissue Regeneration. Introduction to Materials Science. Biomaterials. In Vitro Assessment of Cell–Biomaterial Interactions. Host Response to Biomaterials and Its Implications in Regenerative Engineering. Organ Regenerative Engineering: Cell Sources, Considerations, and Strategies. Cardiovascular Regenerative Engineering. Bone Regenerative Engineering. Engineering Tissueto-Tissue Interfaces. Neural Regenerative Engineering. Ligament Regenerative Engineering. Skeletal Muscle Regenerative Engineering. Engineering Limb Regeneration: Lessons from Animals That Can Regenerate. Index. Catalog no. K10724, June 2013, 435 pp. ISBN: 978-1-4398-1412-3, $99.95 / £63.99
The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date educational framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living system into which they are implanted. The book explains in vitro and in vivo testing paradigms and provides numerous examples on experimental design, laboratory assays, and animal models. Emphasizing the importance of the regulatory process, it describes how innovation in the biomaterials process relates to patentability and inventorship. • Covers wound healing biology and host response to implanted biomaterials • Examines the regulatory process, including standardized product testing • Reviews the innovativeness of biomaterials, with inventorship and patents in mind • Considers experimental design, basic scientific methods, and statistics • Includes extensive references for further study • Contains end-of-chapter questions and answers
Selected Contents: Biology, Biomechanics, Biomaterial Interactions: Wound Healing Biology; Cellular Mechanics; Materials–Host Interactions. Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Standardized Materials Testing; Statistics. Biomaterials Compositions. Biomaterials Applications. Index. Catalog no. K10637, November 2011, 644 pp. ISBN: 978-1-4398-1256-3, $125.95 / £51.99 Also available as an eBook
Also available as an eBook
For more information and complete contents, visit www.crctextbooks.com
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BioMEMS, BioNEMS, and Biomaterials Understanding Nanomedicine An Introductory Textbook Rob Burgess Medical Nanotechnologies Incorporated, Richardson, Texas, USA
This book addresses the latest findings and intriguing possibilities in nanomedicine, drawing on real data and published research from the medical sciences. It comprehensively covers a broad range of therapeutic and diagnostic applications of nanotechnology, providing descriptions of cutting-edge discoveries along with historical perspectives. The text focuses on nanomaterials and nanoparticles—the sectors that hold the most promise for the future of medicine. The book presents the impact of nanotechnology in major medical areas including cancer treatment, clinical neuroscience, tissue engineering, and drug delivery. Also covered is the worldwide governmental regulatory impact on nanomedicine. Catalog no. N10477, June 2012, 524 pp. ISBN: 978-981-4316-38-5, $149.95 / £95.00
From MEMS to Bio-MEMS and Bio-NEMS Manufacturing Techniques and Applications Marc J. Madou University of California, Irvine, USA
This book details manufacturing techniques applicable to bio-nanotechnology. The book first reviews MEMS techniques, materials, and modeling. It then covers nanofabrication, genetically engineered proteins, artificial cells, nanochemistry, and self-assembly. The book also discusses scaling laws in MEMS and NEMS, actuators, fluidics, and power and brains in miniature devices. It concludes with coverage of various MEMS and NEMS applications. This color text offers end-of-chapter problems, worked examples throughout, extensive references, and PowerPoint slides for download. Catalog no. 5516X, June 2011, 650 pp. ISBN: 978-1-4200-5516-0, $109.95 / £69.99 Also available as an eBook
Also available as an eBook
Biomedical Microsystems Ellis Meng University of Southern California, Los Angeles, USA
The book begins with an introduction on the benefits of miniaturization. It then presents a rigorous and indepth treatment of biomedical microelectromechanical systems (BioMEMS) including materials, methods, processes, and concepts. The author covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The book then explores several important applications of BioMEMS such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering. It also describes research and commercialized BioMEMS devices as well as emerging applications. Detailed examples, exercises, and illustrations help clarify the concepts included. Catalog no. 51229, September 2010, 408 pp. ISBN: 978-1-4200-5122-3, $104.95 / £65.99
A Laboratory Course in Biomaterials Wujing Xian University of Illinois at UrbanaChampaign, USA
A teaching tool for instructors in biomaterials and bioengineering, this volume is a comprehensive laboratory textbook with detailed, stepby-step descriptions of lab procedures and explanations. It trains readers in laboratory skills, data analysis, problem solving, and scientific writing. The book integrates principles from materials science, chemistry, biochemistry, cell biology, and engineering. Many of the experiments presented are adapted from research papers to reflect recent progress in biomaterials and bioengineering. The text includes text boxes with in-depth information, case studies, and lab tips as well as information on equipment, reagents, and supplies. Catalog no. 75829, June 2009, 216 pp., Soft Cover ISBN: 978-1-4200-7582-3, $74.95 / £45.99 Also available as an eBook
Also available as an eBook
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BioMEMS, BioNEMS, and Biomaterials A Laboratory Course in Tissue Engineering Melissa Kurtis Micou University of California, San Diego, USA
Dawn Kilkenny University of Toronto, Ontario, Canada
This book contains 15 standalone experiments based on both classic and modern approaches. Experiments encompass a set of widely applicable techniques including cell culture, microscopy, histology, immunohistochemistry, mechanical testing, soft lithography, and common biochemical assays. The book presents experiments using equipment commonly found in labs equipped for tissue culture thus minimizing the cost of reagents. In addition to teaching specific techniques, the experiments emphasize engineering analysis, mathematical modeling, and statistical experimental design. It also describes multiple formats useful for the presentation of results, including technical posters, extended abstracts, and technical reports. The book includes pre- and post-lab questions for each experiment. Catalog no. K13694, August 2012, 304 pp., Soft Cover ISBN: 978-1-4398-7893-4, $62.95 / £40.99
BioMEMS Science and Engineering Perspectives Simona Badilescu Concordia University, Montreal, Quebec, Canada
Muthukumaran Packirisamy Concordia University, Montreal, Quebec, Canada
This books supports the multidisciplinary learning involved in the development of biomicrosystems. It presents a balanced introduction of the biological, engineering, application, and commercialization aspects of the field. With a focus on molecules of biological interest, the book explores the building blocks of cells and viruses as well as linkers, molecules that form the self-assembled monolayers (SAMs), and hydrogels used for making different surfaces biocompatible through functionalization. The book covers fabrication techniques and includes problems in each chapter in addition to real-life examples. Catalog no. K10877, April 2011, 368 pp. ISBN: 978-1-4398-1699-8, $109.95 / £69.99 Also available as an eBook
Also available as an eBook
Ultrasonic and Electromagnetic NDE for Structure and Material Characterization Engineering and Biomedical Applications Edited by
Tribikram Kundu The University of Arizona, Tucson, USA
Most books on nondestructive evaluation (NDE) focus either on the theoretical background or on advanced applications. Bridging the gap between the two, this book brings together the principles, equations, and applications of ultrasonic and electromagnetic NDE in a single, authoritative resource. It begins with the fundamentals of mechanics and electromagnetic theory and then covers state-of-the-art topics and applications. These include structural health monitoring, acoustic microscopy, terahertz imaging, and more. The book includes questions, problems, and workedout examples as well as hundreds of illustrations.
Forthcoming!
Biomaterials A Basic Introduction Qizhi Chen Monash University, Clayton, Australia
George Thouas The multidisciplinary field of biomaterials incorporates principles from fields as diverse as materials science, engineering, cell biology, and medicine. This textbook provides an appropriate balance between depth and broadness of coverage to enable understanding of the most important concepts and principles at the right level by students from a wide academic spectrum. The book introduces the fundamental science relevant to biomaterials and presents the properties and principles of biomaterials from the point of view of clinical applications. The book includes learning objectives, chapter highlights, laboratory practices, problems, and references. Catalog no. K22550, November 2014, c. 736 pp. ISBN: 978-1-4822-2769-7, $119.95 / £76.99 Also available as an eBook
Catalog no. K11655, June 2012, 890 pp. ISBN: 978-1-4398-3663-7, $139.95 / £80.00 Also available as an eBook
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BioMEMS, BioNEMS, and Biomaterials New!
Design of Biomedical Devices and Systems Third Edition Paul H. King, Richard C. Fries, and Arthur T. Johnson
“This book is a comprehensive overview of all the pieces that need to come together to bring a medical device from an idea to approved device. It is an impressive compilation of information that is not easily found elsewhere, and includes extensive references for every chapter. The writing is clear, yet succinct. The book is well organized with labeled subsections that let the reader find exactly what content he/she may want to explore. Each chapter has exercises that can be used as a self-assessment or to supplement a class.” —Anna Iwaniec Hickerson, Keck Graduate Institute of Applied Life Sciences, Claremont, California, USA
Design of Biomedical Devices and Systems, Third Edition covers the design of biomedical engineering devices and systems. The book strongly emphasizes and clarifies the standards of design procedure. Following best practices for conducting and completing a design project, it outlines the various steps in the design process in a basic, flexible, and logical order.
What’s New in the Third Edition: This latest edition contains a new chapters on biological engineering design, product development, and FDA regulations for items other than devices such as drugs. It adds mathematical modeling tools and provides new information on clinical trials and sterilization methods. This new edition: • Familiarizes the reader with medical devices, their design, regulation, and use • Emphasizes a practical, hands-on approach to device design
A substantial revision of a solid text, the third edition includes information on bioprocessing and devotes more instruction to integrating medical and biological considerations with engineering. It features updates to all chapters as well as new problems, examples, and case studies throughout.
Selected Contents: Introduction to Biomedical Engineering Design. Fundamental Design Tools. Design Team Management, Reporting, and Documentation. Product Definition. Product Documentation. Product Development. Hardware Development Methods and Tools. Software Development Methods and Tools. Human Factors. Industrial Design. Biomaterials and Material Testing. Risk Analysis—Devices and Processes. Testing. Analysis of Test Data. Product Liability and Accident Investigations. The FDA and Devices. Food and Drug Administration History and Relevant Nondevice Regulations. Biological Engineering Designs. International Regulations and Standards. Intellectual Property: Patents, Copyrights, Trade Secrets, and Licensing Patents. Manufacturing and Quality Control. Miscellaneous Issues. Professional Issues. Concept to Product? Suggested Reading. Appendices. Visit www.crcpress.com for complete contents
Catalog no. K16421, August 2014, c. 505 pp. ISBN: 978-1-4665-6913-3, $129.95 / £82.00 Also available as an eBook
• Provides an overview of basic design issues • Considers device safety aspects • Discusses the need for documentation • Provides a summary of key ways to protect intellectual property • Discusses the legal ramifications of medical device development and failure
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Biomedical Imaging Introduction to Nuclear Science
Practical Ultrasound
Second Edition
An Illustrated Guide, Second Edition
Jeff C. Bryan University of Wisconsin–La Crosse, USA
This introductory textbook provides a clear and complete introduction to nuclear chemistry and physics— from basic concepts to nuclear power and medical applications. The book covers energetics, nuclear stability, radioactive decay, nuclear reactions, interactions of radiation with matter, detection methods, and safety measures such as monitoring and regulations. It explores applications in medicine, power generation, food safety, waste, and weapons. This second edition of a bestseller contains 60 percent more material and includes new chapters on dosimetry as well as new sections on nuclear forensics, radiology, gamma cameras, and decay through proton or neutron emission. This expanded edition provides a much-needed textbook and resource for undergraduate students in science and engineering as well as those studying nuclear medicine and radiation therapy. It also serves as a general introduction to nuclear science for all interested readers. All chapters are updated and contain additional end-of-chapter problems. A new appendix provides nuclear data for all nuclides mentioned.
New to This Edition: • More in-depth coverage of nuclear reactors and recent accidents such as the one in Fukushima, Japan • A chapter on dosimetry of radiation fields • Expanded discussion of applications • More detailed explanations of the necessary mathematics
Selected Contents: Introduction. Mathematics of Radioactive Decay. Energy and the Nucleus. Applications of Nuclear Science I: Power and Weapons. Radioactive Decay: The Gory Details. Interactions of Ionizing Radiation with Matter. Detection of Ionizing Radiation. Applications of Nuclear Science II: Medicine and Food. Nuclear Reactions. Fission and Fusion. Applications of Nuclear Science III: More about Nuclear Reactors. Radiation Protection. X-ray Production. Dosimetry of Radiation Fields. Appendices. Bibliography. Index. Catalog no. K14329, March 2013, 420 pp. ISBN: 978-1-4398-9892-5, $89.95 / £57.99 Also available as an eBook
Jane Alty Consultant Neurologist, Leeds Teaching Hospitals NHS Trust and Honorary Senior Lecturer, University of Leeds, UK
Edward Hoey Consultant Radiologist, Heart of England NHS Foundation Trust, UK and Honorary Senior Lecturer, University of Birmingham, UK
“The authors are to be congratulated for their efforts. … Not only are you on the brink of discovering a wonderful world of non-invasive imaging, but also your pathway to achieving the competence that you desire will be made considerably easier by this book.” —Henry C Irving FRCR, Consultant Radiologist, St James’s University Hospital, Leeds, UK; Ex-Treasurer of The Royal College of Radiologists
Commended by the British Medical Association, this volume focuses on the scans regularly encountered in a busy ultrasound department and provides everything practitioners need to know to become competent and skilled in scanning. Each chapter contains examples of common and clinically relevant pathologies and discusses the salient features of these conditions. This second edition includes new chapters on breast, musculoskeletal, and Focused Assessment with Sonography in Trauma (FAST) ultrasonography. Beginning with the general principles of ultrasound scanning and a guide to using the ultrasound machine, the book provides step-by-step instructions on how to perform scans and is supplemented by high-quality images and handy tips. • Covers everything a trainee needs to know to become competent in ultrasound scanning • Presents a practical guide, using simple illustrations, accurate images, and uncomplicated language • Provides step-by-step instructions on how to perform ultrasound scans
Selected Contents: General Principles of Ultrasound Scanning. Guide to Using the Ultrasound Machine. Abdomen. Renal, Including Renal Transplant. Abdominal Aorta. Liver Transplant. Testes. Lower Limb Veins. Carotid Doppler Examination. Female Pelvis. Early Pregnancy. Thyroid. Focused Assessment with Sonography in Trauma (FAST). Breast. Musculoskeletal Ultrasound. Index. Catalog no. K17225, August 2013, 295 pp. Soft Cover ISBN: 978-1-4441-6829-7, $79.95 / £49.99 Also available as an eBook
For more information and complete contents, visit www.crctextbooks.com
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Biomedical Imaging New!
Applied Medical Image Processing Second Edition, A Basic Course Wolfgang Birkfellner Medical University of Vienna, Austria
“I mention the book every time I meet someone who asks what the best way is to get into this field.” —Professor Leo Joskowicz, Head of Computer-Assisted Surgery and Medical Image Processing Laboratory, The Hebrew University of Jerusalem, Israel
Praise for the First Edition: “This is a lucid, well-written, and hands-on textbook that explains in simple terms—and with examples— the basic issues of medical image processing. It contains many examples and useful programs.” —Professor Leo Joskowicz, Head of Computer-Assisted Surgery and Medical Image Processing Laboratory, The Hebrew University of Jerusalem, Israel
“The plethora of examples in each chapter … allows the reader to apply the theory and visually assess the outcomes. This book is a perfect blend of theory and practice. I highly recommend it.” —Dr. Pascal Fallavollita, Technical University of Munich, Germany
Avoiding excessive mathematical formalisms, this second edition of a bestseller delivers an ideal introduction to medical image processing, presenting key principles and algorithms using simple MATLAB®/Octave scripts. It discusses data storage, transformations, segmentation, rendering, registration, and reconstruction and also has a chapter on clinical applications as well as an image-guided therapy tutorial. Including examples from radiology, internal medicine, surgery, and radiation therapy, the text is helpful to students of medical physics, biomedical engineering, computer science, and applied mathematics as well as radiology professionals.
Selected Contents: A Few Basics of Medical Image Sources. Image Processing in Clinical Practice. Image Representation. Operations in Intensity Space. Filtering and Transformations. Segmentation. Spatial Transforms. Rendering and Surface Models. Registration. CT Reconstruction. A Tutorial on Image Guided Therapy. A Selection of MATLAB® Commands. Catalog no. K15380, March 2014, 455 pp. ISBN: 978-1-4665-5557-0, $79.95 / £49.99 Also available as an eBook
Biomedical Signal and Image Processing Second Edition Kayvan Najarian Virginia Commonwealth University, Richmond, USA
Robert Splinter University of North Carolina at Charlotte, USA
This book has received wide and welcome reception from universities and industry research institutions alike. It addresses the application of standard and novel processing techniques to biomedical signals and images. The first section presents an introduction to digital signal and image processing, including Fourier transform, image filtering, edge detection, and wavelet transform. The second section investigates specific biomedical signals, such as ECG, EEG, and EMG. The third section focuses on imaging using CT, x-ray, MRI, ultrasound, positron, and other biomedical imaging techniques. Retaining all of the quality and precision of the first edition, the book offers numerous additional examples— predominantly MATLAB®-based—to illustrate the concepts described in the text and to ensure a complete understanding of the material. The author takes great care to clarify ambiguities in some mathematical equations and to further explain and justify the more complex signal and image processing concepts thus offering a complete and understandable approach to complicated concepts. • Includes updates for all chapters as well as many additional examples • Employs understandable descriptions of mathematical techniques • Provides a simple approach to complicated concepts • Presents newly revised and expanded end-of-chapter problems
Selected Contents: Introduction To Digital Signal And Image Processing: Signals and Biomedical Signal Processing. Fourier Transform. Image Filtering, Enhancement, and Restoration. Edge Detection and Segmentation of Images. Wavelet Transform. Other Signal and Image Processing Methods. Clustering and Classification. Processing Of Biomedical Signals: Electrical Activities of Cell. Electrocardiogram. Electroencephalogram. Electromyogram. Other Biomedical Signals. Processing Of Biomedical Images: Principles of Computed Tomography. X-Ray Imaging and Computed Tomography. Magnetic Resonance Imaging. Ultrasound Imaging. Positron Emission Tomography. Other Biomedical Imaging Techniques. Related Titles. Catalog no. K13235, May 2012, 411 pp. ISBN: 978-1-4398-7033-4, $119.95 / £70.99 Also available as an eBook
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Biomedical Imaging Biosignal and Medical Image Processing Third Edition
Physics for Diagnostic Radiology Third Edition
John L. Semmlow
P. P. Dendy
Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Addenbrookes NHS Trust, Cambridge, UK
B. Heaton
Benjamin Griffel
Aberdeen Radiation Protection Services, UK
This third edition of a bestseller offers comprehensive coverage of the major approaches in biomedical signal and image processing. It provides a complete set of signal processing tools, including diagnostic decisionmaking tools and classification methods. Thoroughly revised and updated, it supplies important new material on nonlinear methods for describing and classifying signals, including entropy-based methods and scaling methods. This edition covers data “cleaning” methods commonly used in areas such as heart rate variability studies along with actual examples. It also includes new end-of-chapter problems. This is the first and only textbook to supply a handson tutorial in biomedical signal and image processing and offers a unique and proven approach to signal processing instruction, unlike any other competing source on the topic. The book also showcases valuable implementation procedures, common pitfalls, and essential application concepts. The text is accompanied by a CD with support data files and all MATLAB® examples and figures found in the text. • Offers a substantial revision to a well-established textbook • Adds new material on nonlinear methods for describing and classifying signals • Supplies new end-of-chapter problems and examples • Includes studies dealing with heart rate variability as actual examples • Incorporates MATLAB® throughout the text
Selected Contents:
“This is the third edition of a well-established and popular textbook on physics of diagnostic radiology… The textbook describes recent state-of-the-art advances in medical imaging in a way radiologists, radiographers, and medical physicists will find easy to understand. It is internationally recognized as one of the key textbooks in its field.” —Dr. Keith Faulkner, North East Strategic Health Authority, UK
Praise for the Second Edition: “One of the most useful features is the amount of review material. A series of discussion questions are given at the end of each chapter and six to fourteen multiplechoice questions per chapter are listed in an appendix, with an answer key for all questions and explanatory footnotes for some … On the whole, I found the material to be authoritative, comprehensive, and accurate.” —Doody Online Reviews
Fully revised and updated, this bestseller helps readers understand how various imaging techniques work. This edition includes new chapters on PET and PACS as well as new material on digital receptors, radiation doses, and risks to patients as well as special radiographic techniques including subtraction techniques and interventional radiology. It also emphasizes the differences between analog and digital images and covers other topics including multi-slice CT and three-dimensional resolution, dual energy applications, and cone beam CT. The book includes exercises, multiple choice questions, extensive references, and suggestions for further reading.
Selected Contents:
Introduction. Basic Concepts. Spectral Analysis: Classical Methods. Digital Filters. Spectral Analysis: Modern Techniques. Time–Frequency Analysis. Wavelet Analysis. Advanced Signal Processing Techniques: Optimal and Adaptive Filters. Multivariate Analyses: Principal Component Analysis and Independent Component Analysis. Fundamentals of Imaging Processing: MATLAB® Image Processing Toolbox. Spectral Analysis: The Fourier Transform. Image Segmentation. Image Reconstruction. Classification I: Linear Discriminant Analysis and Support Vector Machines. Adaptive Neural Nets.
Fundamentals of Radiation Physics and Radioactivity. Production of X-Rays. Interaction of X-Rays and Gamma Rays with Matter. Radiation Measurement. The Image Receptor. The Radiological Image. Assessment of Image Quality and Optimisation. Tomographic Imaging with X-Rays. Special Radiographic Techniques. Diagnostic Imaging with Radioactive Materials. Positron Emission Tomographic Imaging (PET). Radiobiology and Generic Radiation Risks. Radiation Doses and Risks to Patients. Practical Radiation Protection and Legislation. Diagnostic Ultrasound. Magnetic Resonance Imaging. Digital Image Storage and Handling. Multiple Choice Questions. Index.
Catalog no. K16329, February 2014, 630 pp. ISBN: 978-1-4665-6736-8, $119.95 / £76.99
Catalog no. 83155, August 2011, 720 pp. ISBN: 978-1-4200-8315-6, $83.95 / £51.99
Also available as an eBook
Also available as an eBook
For more information and complete contents, visit www.crctextbooks.com
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Biomedical Imaging Webb's Physics of Medical Imaging
Rapid Review of Radiology Shahid Hussain, Sherif Aaron Abdel Latif, and Adrian David Hall
Second Edition Edited by
Series: Medical Rapid Review Series
M. A. Flower Institute of Cancer Research/Royal Marsden NHS Foundation Trust, UK
Series: Series in Medical Physics and Biomedical Engineering
“Possibly the most comprehensive book on the subject currently on the market.” —Dr. Sandro Olivo, University College London
“Despite its small size, this case-based review of diagnostic radiology is remarkably comprehensive... Overall, this book is of very high quality and would be quite useful for senior radiology trainees in the U.K. and radiology residents preparing for American Board of Radiology exams.” (5 stars) —Dana Smetherman, MD, Ochsner Clinic Foundation, Doody's Review Service
Praise for the First Edition: “Steve Webb has produced a first-class book. Because The Physics of Medical Imaging is up to date in a rapidly changing field, it is the text of choice for teaching graduate research students in this new and exciting subspecialty of physics.” —Physics Today
“… a worthwhile addition to the personal library of anyone connected with this field.” —Journal of Clinical Physics and Physiological Measurement
Since the publication of the best-selling first edition, the technology and clinical applications of medical imaging have changed significantly. Gathering these developments into one volume, this comprehensive second edition presents the basic physics, modern technology, and up-to-date examples of clinical application across all the modalities of medical imaging. It now covers state-of-the-art detector technology and computer processing used in medical imaging. Along with many new examples and figures, this edition includes new chapters on medical image processing and multimodality imaging.
As in all specialties, learning in radiology is a life-long process. But for radiologists in training, there are vast amounts of information to assimilate. In this book, the authors have compiled 191 cases to help the reader with practical aspects of image recognition and differential diagnosis. The selection of cases is broad enough to provide an introduction to some readers, but also includes more testing cases for those in the later stages of training. Each self-test case is presented with one or more images, along with pertinent clinical details. The solution and explanation is also presented along with differential diagnoses that logically derive from the images and history. The correct diagnosis is followed by discussion of the underlying problem, strategy points, and main imaging findings. The book contains 500 images including x-rays, ultrasound, CT, MRI, interventional techniques, and nuclear medicine imaging. It is of value to radiologists in training and other health professionals wishing to improve their radiological skills and is the first book for the FRCR Part 2B exam.
Selected Contents:
Selected Contents:
In the Beginning: The Origins of Medical Imaging. Diagnostic Radiology with X-Rays. X-Ray Transmission Computed Tomography. Clinical Applications of X-Ray Computed Tomography in Radiotherapy Planning. Radioisotope Imaging. Diagnostic Ultrasound. Spatially Localised Magnetic Resonance. Physical Aspects of Infrared Imaging. Imaging of Tissue Electrical Impedance. Optical Imaging. Mathematics of Image Formation and Image Processing. Medical Image Processing. Perception and Interpretation of Images. Computer Requirements of Imaging Systems. Multimodality Imaging. Epilogue. Index.
General Introduction. Chest Imaging. Abdominal Imaging. Central Nervous System Head and Neck Imaging. Musculoskeletal Imaging. Pediatric Imaging. Breast Imaging. Catalog no. K21978, May 2010, 352 pp., Soft Cover ISBN: 978-1-84076-120-7, $75.95 / £46.99
Catalog no. IP743, June 2012, 864 pp. ISBN: 978-0-7503-0573-0, $93.95 / £51.99 Also available as an eBook
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Biomedical Imaging New!
Magnetic Resonance Imaging The Basics Christakis Constantinides University of Cyprus, Nicosia
This book provides a solid introduction to the fundamentals of MRI technology. Based on courses taught at The Johns Hopkins University, the book provides an overview of magnetic resonance and examines the principles of physics for nuclear magnetic resonance (NMR) signal formation and image construction. It explains the mathematical formulation of MRI and discusses image quantitative indices. Additional topics include Fourier transformations, hardware and electronics of an MRI scanner, magnetic fields, and NMR spectroscopy and spectral acquisition and imaging techniques. The book includes worked examples and problem sets to explain the concepts taught. Catalog no. K22099, March 2014, 235 pp. Soft Cover ISBN: 978-1-4822-1731-5, $69.95 / £44.99 Also available as an eBook
Clark's Essential Physics in Imaging for Radiographers
Image Processing with MATLAB® Applications in Medicine and Biology, Second Edition Omer Demirkaya, Musa H. Asyali, and Prasanna K. Sahoo Image Processing with MATLAB®: Applications in Medicine and Biology explains complex, theory-laden topics through examples and MATLAB® algorithms. It describes classical as well emerging areas in image processing and analysis. Reducing the need for the trial-and-error way of solving problems, this book helps readers understand advanced concepts by applying algorithms to realworld problems in medicine and biology. Each chapter has been revised and updated with new chapters added in morphological operations, validation of image analysis methods, and image registration. Substantial updates have been given to chapters on medical imaging systems, image segmentation methods, and deformation models. The book also includes new modalities such as ultrasound, and more. • Includes several new contributors as experts in their respective fields • Contains new questions and examples • Adds new chapters on image registration, morphological operations, and validation of image analysis methods
Ken Holmes, Marcus Elkington, and Phil Harris
• Features a solutions manual available for instructors wishing to convert this reference to classroom use
An invaluable tool for students, assistant practitioners, and radiographers, this easyto-understand pocket guide provides an accessible introduction to the study of physics in imaging for radiographers in a reader-friendly format. With diagrams and photographs to support the text, each chapter provides clear learning objectives and a series of MCQs to test reader assimilation of the material. The book opens with overviews of image production, basic mathematics and physics relevant to medical imaging, and follows with detailed chapters on the physics relevant to producing diagnostic images using x-rays. Features diagrams and photographs to support the text.
Catalog no. K22900, March 2015, c. 475 pp. ISBN: 978-1-4822-3246-2, $99.95 / £63.99 Also available as an eBook
Catalog no. K18088, October 2013, 214 pp. Soft Cover ISBN: 978-1-4441-4561-8, $31.95 / £19.99 Also available as an eBook
For more information and complete contents, visit www.crctextbooks.com
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Biotechnology Algorithms in Bioinformatics
New!
Robotic Surgery
A Practical Introduction Wing-Kin Sung National University of Singapore
“This aptly titled book is a timely publication that details several algorithms widely used in bioinformatics. … This work can serve as a reference guide for students and researchers attempting to implement or learn algorithms relevant to bioinformatics. Although some concepts referenced in the book specifically target advanced bioinformatics experts, general users should not be discouraged from reading this work. …Summing Up: Recommended.” —CHOICE, June 2010
“… an excellent guide. The book is appropriate for advanced undergraduates and graduates in mathematics or CS. … The 27-page introduction is the most efficient concept-building summary and explication of molecular biology that I have encountered. … Section 1.8 sets a new, high standard for sciencehistory exposition, covering Gregor Mendel to the present. …This self-contained, well-designed, and well-written book, with its many good exercises, bibliographic references, and photo-quality figures, is an ideal introduction to bioinformatics.” —George Hacken, Computing Reviews, March 2010
This classroom-tested text provides an in-depth introduction to the algorithmic techniques applied in bioinformatics. For each topic the author clearly details the biological motivation, precisely defines the corresponding computational problems, and includes detailed examples to illustrate each algorithm. The text covers basic molecular biology concepts, sequence similarity, the suffix tree, sequence databases, sequence and genome alignment, the phylogenetic tree, genome rearrangement, motif finding, the secondary structure of RNA, peptide sequencing, and population genetics. Supplementary material is provided on the author’s website and a solutions manual is available for qualifying instructors.
Selected Contents: Introduction to Molecular Biology. Sequence Similarity. Suffix Tree. Database Search. Multiple Sequence Alignment. Genome Alignment. Phylogeny Reconstruction. Phylogeny Comparison. Genome Rearrangement. Motif Finding. RNA Secondary Structure Prediction. Peptide Sequencing. Population Genetics. References. Index.
With Smart Materials, Robotic Structures, and Artificial Muscles Mohsen Shahinpoor University of Maine, Orono, USA
Siavash Gheshmi University of Maine, Orono, USA
In recent years robotic surgery has garnered a great deal of interest due to its non-invasive surgical approach. This book focuses on robotic surgery and biomimetic artificial muscles and their possible engineering, industrial, medical, and science applications. It presents the fundamentals of surgical robots, including the design of their geometrical configurations, kinematics, dynamics, and control. It also describes systems that can be manufactured or fabricated to act like biomimetic artificial muscles, sensors, and actuators. This book is expected to include an introductory general chapter on the history of robotic surgery and biomimetic artificial muscles and their possible engineering, industrial, medical, and science applications. Other chapters are expected to cover the fundamentals of surgical robots such as design of their geometrical configurations, kinematics, dynamics, and control. Also discussed are the designs of ophthalmic surgical robots, general laparoscopic surgical robots, and applications of a number of particular materials and systems that are currently available. • Serves as a textbook on robotic surgery education • Addresses the applications of artificial muscles, smart materials, and sensors to robotic surgery • Includes end-of-chapter homework problems and MATLAB® codes for the diagrams in the appendix
Selected Contents: Introduction to Surgical Robots General Configurations. Surgical Robots Kinematics and Workspace. Intraocular Robotic Surgical Systems. Deployable Laparoscopic Robotic Surgical Systems. Applications of Intelligent Materials and Artificial Muscles to Robotic Surgery. Summary and Conclusions. References. Appendix. Index. Catalog no. N11018, August 2014, c. 300 pp. ISBN: 978-981-4316-23-1, $179.95 / £114.00
Catalog no. C7033, November 2009, 407 pp. Pack - Book and Ebook ISBN: 978-1-4200-7033-0, $91.95 / £43.99 Also available as an eBook
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Biotechnology Learning Bio-MicroNanotechnology
Biotechnology Fundamentals
Mel I. Mendelson
Manipal University, Dubai, UAE
Loyola Marymount University, Los Angeles, California, USA
This textbook discusses the fundamentals of biotechnology as well as recent related developments such as stem cell research, cloning, biofuel, transgenic plants, genetically modified food, pharmacogenomics, and nanobiotechnology. Incorporating extensive pedagogy into the content, the authors provide examples, endof-chapter problems case studies, and laboratory tutorials. The book also includes definitions, historical perspectives, time lines, and major discoveries along with information on biotechnology products, current research and development, career prospects, ethical issues, and future trends.
“… a great combination of two key disciplines in the coming quarter of this century, biotechnology and nanotechnology. This will be a good guidebook for the academic adventure as well as a bible for the pioneer in the engineering and scientific field.” —Hideyuki Kanematsu, Suzuka National College of Technology
“… provides an excellent, multi-dimensional approach to learning that I have not seen in other nanotechnology textbooks.” —Kory Goldammer, Richland College
A primary text for undergraduate nanotechnology courses, this book is designed for students who lack a cross-disciplinary background and knowledge of micro and nanotechnology. Clearly and concisely written, it contains many examples, questions, and problems divided into three hierarchical learning skills: understanding, analyzing, and evaluating concepts. The author attempts to break down the boundaries between biology, chemistry, physics, engineering, and ethics. He accomplishes this by co-mingling the vocabulary and concepts of these disciplines around bio-applications. Copiously illustrated, this new text leans heavily towards biological and biomedical applications and includes a comprehensive chapter on ethics. • Introduces micro/nanotechnology vocabulary, concepts, and applications from first principles • Emphasizes learning with thinking exercises, analogies, and study questions • Includes team assignments and assessment exercises • Discusses nanotechnology and cancer, risks, ethics, and future predictions
Firdos Alam Khan
• Includes information on current research trends • Covers novel medical genetics topics such as intra-uterine insemination • Discusses the process of biotech product development, with suitable examples • Examines ethical issues within biotechnology research and product development
Selected Contents: Introduction to Biotechnology. Genes and Genomics. Proteins and Proteomics. Recombinant DNA Technology. Microbial Biotechnology. Agricultural Biotechnology. Animal Biotechnology. Environmental Biotechnology. Medical Biotechnology. Nanobiotechnology. Product Development in Biotechnology. Industrial Biotechnology. Ethics in Biotechnology. Careers in Biotechnology. Laboratory Tutorials. Glossary. Catalog no. K11059, September 2011, 608 pp. ISBN: 978-1-4398-2009-4, $98.95 / £51.99 Also available as an eBook
Selected Contents: Thinking Small and Big. Biomolecules and Cells. Molecular Chemistry. Bit of Physics. Engineering Bits and Bytes. Seeing Small Things. Nanoelectronics. Microelectromechanical Systems. Nanotechnology and Cancer. Risks: Nano or Mega? Ethics and Social Relevance. Self-Assembled Future. Appendices. Catalog no. 82035, January 2013, 611 pp. ISBN: 978-1-4200-8203-6, $89.95 / £57.99 Also available as an eBook
For more information and complete contents, visit www.crctextbooks.com
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Biotechnology Introduction to Instrumentation in Life Sciences Prakash Singh Bisen Defense Research & Development Establishment, Gwalior, India
Anjana Sharma Rani Durgavati University, Jabalpur, India
“A comprehensive textbook on instrumentation methods which covers all major topics including practical exercises representing the syllabi of various postgraduate and undergraduate programs in life sciences.” —Prof. Vinay Sharma, Prof. & Head, Dept. of Bioscience & Biotechnology, Banasthali University, India
“The proposed book is an excellent one for use of students, research scholars and teachers of life sciences, biotechnology, biochemistry, biophysics and other related disciplines where such books exclusively dedicated for life sciences are not available.” —Prof. Sukh Mahendra Singh, Coordinator, School of Biotechnology, Banaras Hindu University, India
Addressing aspects of instrumentation that hold the key for cutting-edge research and innovative applications, this book is designed to serve a wide range of students and researchers in the diversified fields of life sciences including pharmacy, biotechnology, microbiology, biochemistry, and environmental sciences. The book is unique in its broad subject coverage, incorporating fundamental techniques as well as applications of modern molecular and proteomic tools that are the basis for state-of-the-art research. It includes well-illustrated diagrams to explain the principles and theories behind the instruments described. • Includes basic theoretical and practical details for numerous types of chromatography • Describes a broad range of spectroscopic techniques • Contains unique in-depth coverage of fermentation processes • Offers an excellent bench manual for researchers
Selected Contents: Microscopy. Micrometry. Electrochemical Techniques. Chromatography. Spectroscopy. Centrifugation. Electrophoresis. X-Ray Microanalysis. Techniques with Radioisotopes. Fermentation. Conductivity Meters. Glossary. Index. Catalog no. K14893, September 2012, 383 pp. Soft Cover ISBN: 978-1-4665-1240-5, $83.95 / £51.99 Also available as an eBook
Biotechnology Operations Principles and Practices Michael J. Roy University of Wisconsin-Madison, USA
Due to rapid developments in the biotechnology industry— and the wide range of disciplines that contribute to its collective growth—there is a need to more carefully plan and fully integrate biotech development projects. Despite the wealth of operations experience and associated literature available, no single book has yet offered a comprehensive, practical guide to fundamentals. Filling this void, this book presents an integrative philosophy serving as a practical guide for students, professionals, or anyone else with interests in the biotech industry. Using simple language and explanatory figures, this book describes the functional areas that must be successfully integrated to safely and efficiently bring a biotechnology product to market. Although many books emphasize specific technical aspects of biotech, this is perhaps the first to integrate essential concepts of product development and scientific and management skills with the seven functional areas of biotechnology: • • • • • • •
Biomanufacturing Clinical trials Nonclinical studies Project management Quality assurance Quality control Regulatory affairs
A practical roadmap to optimizing biotechnology operations, this reference illustrates how to use specific product planning, design, and project management processes to seamlessly merge plans and efforts in key functional areas. Applying lessons learned throughout the nascent history of biotech, the author highlights developmental principles that could help bring future products to market with increased safety and efficiency. Drawing from his experiences working in both industry and government, the author clarifies basic methodologies and practices to help reduce risks and resolve problems as future technological discoveries are developed into tangible products.
Selected Contents: Introduction to Biotechnology Operations: Planning for Success. Project Management. Regulatory Affairs. Regulatory Compliance. Quality Systems. Biomanufacture. Quality Control. Nonclinical Studies. Clinical Trials. Glossary. Additional Reading. Practical Problems and Questions. Catalog no. K11486, March 2011, 416 pp. ISBN: 978-1-4398-3027-7, $119.95 / £69.99 Also available as an eBook
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Biotechnology Forthcoming!
Nanotechnology Understanding Small Systems, Third Edition Ben Rogers, Jesse Adams, and Sumita Pennathur Series: Mechanical and Aerospace Engineering Series
“The book is well written with lots of examples and historic perspectives that certainly make reading more enjoyable and stimulating.” —Dr. Prabhu Arumugam, Louisiana Tech University, Ruston, USA
Nanotechnology is a gigantic topic about small things. This book uncovers the most important aspects of nanotechnology for the reader. It begins with an overview of nanotechnology emphasizing its history, key personalities, and early milestones. The book then presents the issues, promises, and fundamentals behind nanotechnology. Also covered are a variety of topics including nanomaterials, nanomechanics, nanoelectronics, nanoscale heat transfer, nanophotonics, nanoscale fluid mechanics, nanobiotechnology, and nanomedicine. In these “nano” chapters the authors discuss the specific, fundamental differences between macroscale and nanoscale phenomena and devices—using applications to teach key concepts. This is a substantial revision of one of the first true primary texts in nanotechnology. The second edition was a CHOICE Award winner in 2011. Each chapter in the third edition has been thoroughly revised and updated. It also includes a major chapter on nanomedicine. This edition: • Includes new personality profiles and sidebars to emphasize the people and history of the field • Provides the latest understanding of the human health ramifications of nanomaterials • Incorporates new problems, examples, and an exhaustive nanotech glossary • Provides a list of recommended resources for further study
Catalog no. K21691, October 2014, c. 432 pp. ISBN: 978-1-4822-1172-6, $99.95 / £72.99 Also available as an eBook
Selected Contents: Big Picture and Principles of the Small World: Understanding the Atom: Ex Nihilo Nihil Fit. Nanotechnology Starts with a Dare: Feynman’s Big Little Challenges. Why One-Billionth of a Meter Is a Big Deal. Thinking It Through: The Broad Implications of Nanotechnology. The Business of Nanotech: Plenty of Room at the Bottom Line Too. Introduction to Miniaturization: Background: The Smaller, the Better. Scaling Laws. The Basics of Quantum Mechanics. Summary. Introduction to Nanoscale Physics: Background: Newton Never Saw a Nanotube. One Hundred Hours and Eight Minutes of Nanoscale Physics. The Basics of Quantum Mechanics. Summary. Nanomaterials: Background: Matter Matters. Bonding Atoms to Make Molecules and Solids. Crystal Structures. Structures Small Enough to Be Different (and Useful). Summary. Nanomechanics: Background: The Universe Mechanism. A High-Speed Review of Motion: Displacement, Velocity, Acceleration, and Force. Nanomechanical Oscillators: A Tale of Beams and Atoms. Feeling Faint Forces. Summary. Nanoelectronics: Background: The Problem (Opportunity). Electron Energy Band. Electrons in Solids: Conductors, Insulators, and Semiconductors. Fermi Energy. Density of States for Solids. Turn Down the Volume! (How to Make a Solid Act More Like an Atom). Quantum Confinement. Tunneling. Single Electron Phenomena. Molecular Electronics. Summary. Nanoscale Heat Transfer: Background: Hot Topic. All Heat Is Nanoscale Heat. Conduction. Convection. Radiation. Summary. Nanophotonics: Background: The Lycurgus Cup and the Birth of the Photon. Photonic Properties of Nanomaterials. NearField Light. Optical Tweezers. Photonic Crystals: A Band Gap for Photons. Summary. Nanoscale Fluid Mechanics: Background: Becoming Fluent in Fluids. Fluids at the Nanoscale: Major Concepts. How Fluids Flow at the Nanoscale. Applications of Nanofluidics. Summary. Nanobiotechnology: Background: Our World in a Cell. Introduction: How Biology “Feels” at the Nanometer Scale. The Machinery of the Cell. Applications of Nanobiotechnology. Summary. Nanomedicine: What Is Nanomedicine? Medical Nanoparticles. Nanomedicine and Cancer. Biomimicry in Nanomedicine. Commercial Exploration. Summary. Glossary. Index.
For more information and complete contents, visit www.crctextbooks.com
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General Textbooks Numerical Methods for Chemical Engineers Using Excel, VBA, and MATLAB® Victor J. Law Tulane University, New Orleans, Louisiana, USA
While teaching a course for engineers over the last 15 years, the author found the need for a new textbook—one that was less elementary and provided applications better suited for chemical engineers. Six years’ worth of teaching notes were enhanced to develop this book. Since many practical engineering problems must be solved numerically, this text shows how to use numerical methods and Excel®/VBA for chemical and biomolecular engineering problems. Topics covered include nonlinear equations, Visual Basic, linear algebra, ordinary differential equations, regression analysis, partial differential equations, and mathematical programming methods. The book also includes an introduction to MATLAB®, which becomes easier to learn after studying the programming tools presented in previous chapters. Most of the examples and problems discussed in the text are related to chemical and biomolecular engineering and cover a broad range of application areas including thermodynamics, fluid flow, heat transfer, mass transfer, reaction kinetics, reactor design, process design, and process control. The chapters feature “Did You Know” boxes, which teach readers specific Excel features. Each chapter contains examples that demonstrate how a particular numerical method or programming methodology can be implemented. The book also contains end-of-chapter exercises.
Selected Contents: Roots of a Single Nonlinear Equation. Visual Basic® for Applications Programming. Linear Algebra and Systems of Linear Equations. Numerical Differentiation and Integration. Ordinary Differential Equations (Initial Value Problems). Ordinary Differential Equations (Boundary Value Problems). Regression Analysis and Parameter Estimation. Partial Differential Equations. Linear Programming, Nonlinear Programming, Nonlinear Equations, and Nonlinear Regression Using Solver. Introduction to MATLAB®. Appendix A: Additional Features of VBA. Index. Catalog no. K16702, March 2013, 247 pp. ISBN: 978-1-4665-7534-9, $59.95 / £38.99
Technical Writing A Practical Guide for Engineers and Scientists Phillip A. Laplante The Pennsylvania State University, Malvern, USA
Series: What Every Engineer Should Know
“Concisely written, fast-paced, comprehensive, and written with workplace expectations in mind, Laplante hits the mark when he says his book is intended to complement reference books or other technical communication books… The language is easy for students to understand; the design, graphics, and examples keep readers engaged; and it can be a great supplement or primary text depending on how much original material of your own you would like to provide to your students.” —Diane Martinez, Technical Communication, May 2012
Written by a renowned engineer and widely published technical author, this guide enables readers to write, edit, and publish materials of a technical nature including books, articles, reports, and electronic media. Complementing the traditional writer’s reference manuals and other books on technical writing, this text helps readers understand the practical considerations in writing technical content. Drawing on his own work, the author presents many first-hand examples of writing, editing, and publishing technical materials. This book: • Offers precise, hands-on coverage of technical writing • Explains how to write for blogs, social networks, and other e-media • Incorporates at least one figure, table, graphic, bullet list, or equation on most pages
Selected Contents: The Nature of Technical Writing. Technical Writing Basics. The Writing Process. Scientific Writing. Business Communications. Technical Reporting. Using Graphical Elements. Publishing Your Work. Writing for E-Media. Writing with Collaborators. Glossary. Index. Catalog no. K11106, July 2011, 250 pp., Soft Cover ISBN: 978-1-4398-2085-8, $43.95 / £28.99 Also available as an eBook
Also available as an eBook
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