Bioengineering and Biotechnology

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 1

Teach with the books you trust.™

Request your complimentary inspection copy today!

CRC Press Textbooks

New and Noteworthy Textbooks in

Bioengineering and Biotechnology

WWW.CRCTEXTBOOKS.COM

CRC Press Taylor & Francis Group

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 2

CONTENTS Bio Signals & Systems ............................................3 Biomechanics ..........................................................7 Bio MEMS, NEMS & Materials ................................9 Biomedical Imaging ..............................................15 Biophysics..............................................................17 Page 3

Page 7

Biotechnology ......................................................18 General Textbooks ................................................22

Page 8

Page 9

Page 11

Page 15

For more information and complete tables of contents or to request your complimentary inspection copy visit

www.crctextbooks.com CRC Press Textbooks

1-800-634-7064 • 1-859-727-5000 +44 (0) 1235 400 524 orders@crcpress.com

Teach with the books you trust.™ HJM01 Textbook Minicat_ISSUU_8.08.13_gtr

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 3

Bio Signals & Systems Coming Soon

Systems Biology Mathematical Modeling and Model Analysis Andreas Kremling Technical University Munich, Germany

Series: Chapman & Hall/CRC Mathematical & Computational Biology

This text covers the main aspects of systems biology from a systems theoretical point of view. Systems biology is an emerging research field that incorporates methods and tools from molecular biology, systems theory, and information science in order to understand and infer properties of cellular networks. The book introduces theoretical approaches motivated by systems theory, presents mathematical modeling approaches, and describes methods to analyze the models.

• Presents mathematical modeling approaches for cellular systems • Describes cellular processes such as enzymatic reactions, transport across the cell membrane, signaling, and polymerization • Discusses methods for the analysis of motifs, modules, and large-scale networks

Pedagogical Features • Includes analytical and numerical examples • Provides MATLAB® m-files for all simulation studies Figure slides are available upon qualifying course adoption.

Selected Contents Fundamentals Introduction Biological Basics Fundamentals of Mathematical Modeling Model Calibration and Experimental Design Modeling of Cellular Processes Enzymatic Conversion Polymerization Processes Signal Transduction and Genetically Regulated Systems Analysis of Modules and Motifs General Methods of Model Analysis Aspects of Control Theory Motifs in Cellular Networks Analysis of Cellular Networks Metabolic Engineering Topological Characteristics Appendix Index Catalog no. K16367, October 2013, c. 389 pp.

ISBN: 978-1-4665-6789-4, $79.95 / £49.99 Also available as an eBook

From Esteemed Author Robert B. Northrop University of Connecticut, Storrs, USA

Updated Edition of a Bestseller

Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation Second Edition Series: Biomedical Engineering

This book helps biomedical engineers understand and design signal conditioning systems using analog integrated circuits. It explains the electronic components and subsystems—the "building blocks"—that are used in ECG, EEG, EMG, ERG, tomographic images, biochemical spectrograms, and other crucial medical applications. This second edition has been substantially updated and revised.

• Introduces the basic mathematical tools used to describe noise and its propagation through linear systems • Describes how to improve signal-to-noise ratios with signal averaging and linear filtering • Shows how op amps can be used to build instrumentation amplifiers, active filters, and other systems and subsystems • Features three new chapters on power amplifiers, wireless patient monitoring, and RFID, GPS, and ultrasonic tags

Pedagogical Features • Includes an extensive glossary • Provides end-of-chapter problems and examples that emphasize biomedical electronic applications A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Sources and Properties of Biomedical Signals.

Properties and Models of Semiconductor Devices Used in Analog Electronic Systems. The Differential Amplifier. General Properties of Electronic, SingleLoop Feedback Systems. Feedback, Frequency Response, and Amplifier Stability. Operational Amplifiers and Comparators. Introduction to Analog Active Filters. Instrumentation and Medical Isolation Amplifiers. Noise and the Design of Low-Noise Signal Conditioning Systems for Biomedical Applications.

Digital Interfaces. ...

Catalog no. K12982, March 2012, 578 pp.

ISBN: 978-1-4398-6669-6, $119.95 / £76.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

3

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 4

Bio Signals & Systems From Esteemed Author Robert B. Northrop University of Connecticut, Storrs, USA

Signals and Systems Analysis in Biomedical Engineering Second Edition Series: Biomedical Engineering

Based on the author's 30 years of experience in teaching as well as his personal research on neurosensory systems, this book, now in its second edition, provides a ready source of information on the specialized mathematical techniques most useful in describing and analyzing biomedical signals.

• Includes a comprehensive chapter on joint time-frequency analysis of nonstationary biomedical signals, and the use of wavelets in JTFA

Introduction to Complexity and Complex Systems Written for students and professionals in the fields of biomedical engineering, systems biology, biophysics, and physiology, this unique reference covers complexity issues within living systems.

Topics include human responses to coping with complex systems, the Law of Unintended Consequences, the relation of complexity to evolution, the complexity inherent in invertebrate immune systems, and the complexity inherent in economic systems.

Pedagogical Features

• Explores the mathematics of tomographic imaging

• Provides dynamic models for various complex systems

• Describes the analytical signal and the Hilbert transform

• Offers present-day examples for dealing with complex systems

• Discusses the analysis of nonlinear systems, nonlinear oscillators, and biological clocks

• Supplies homework problems for better comprehension

• Introduces the analysis of and modeling strategies for complex systems

• Includes a glossary

A solutions manual is available upon qualifying course adoption.

Selected Contents

A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents

Introduction to Biomedical Signals and Systems.

Review of Linear Systems Theory. The Laplace Transform and Its Applications. Fourier Series Analysis of Periodic Signals. The Continuous Fourier Transform. The Discrete Fourier Transform.

Introduction to Joint Time-Frequency Analysis of Biomedical Signals. Introduction to the Analysis of Stationary Noise, and Signals Contaminated with Noise. Basic Mathematical Tools Used in the Characterization of Physiological Systems.

Introduction to the Mathematics of Tomographic Imaging. Introduction to the Analysis of Nonlinear Biochemical Systems and Biochemical Oscillators.

Introduction to Complex Systems in Biology and Medicine. Glossary. Appendices.

Introduction to Complexity and Complex Systems.

Introduction to Large Linear Systems. Introduction to Nonlinear Biochemical Systems and Biochemical Oscillators. Modularity, Redundancy, Degeneracy, Pleiotropy and Robustness in Complex Biological Systems. The Evolution of Biological Complexity; Invertebrate Immune Systems. The Complex Adaptive and Innate Human Immune Systems.

Complexity in Quasispecies: MicroRNAs. Introduction to Physiological Complexity: Examples of Models of Some Complex Physiological Systems.

The Quest for Quantitative Measures of Complexity.

"Irreducible and Specified Complexity" in Living Systems. Introduction to Complexity in Economic Systems. Dealing with Complexity. Appendix.

Bibliography and References. Glossary.

Catalog no. K10633, March 2010, 654 pp.

ISBN: 978-1-4398-1251-8, $109.95 / £69.99

Catalog no. K11775, December 2010, 551 pp.

ISBN: 978-1-4398-3901-0, $87.95 / £56.99

Also available as an eBook

Also available as an eBook

4

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 5

Bio Signals & Systems Biomedical Engineering Principles Second Edition Arthur B. Ritter, Vikki Hazelwood, Antonio Valdevit, and Alfred N. Ascione

Praise for the Previous Edition "... not only an in-breadth overview on current BME fields, but also an in-depth analysis of specific selected topics that are supported by appropriate mathematical models, equations, quantitative data charts and tables."

—Biomedical Engineering Online, 2005

"... an excellent textbook for a class. Each chapter contains numerous examples and contains many figures to enhance learning."

—Richard C. Fries, PE, CRE, Baxter Healthcare, Inc., IEEE Engineering in Medicine and Biology Magazine, December 2006

Integrating engineering, medicine, biology, and physics, this book clearly defines basic principles in image processing and biomechanics, modeling physiological processes, and bioelectric signal analysis to build a solid understanding of devices and designs for improved functioning of the human body.

Pedagogical Features • Offers extensive examples • Includes in-chapter problems A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction: Modeling of Physiological Processes.

Cell Physiology and Transport. Principles and Biomedical Applications of Hemodynamics. A Systems Approach to Physiology. The Cardiovascular System. Biomedical Signal Processing. Signal Acquisition and Processing. Techniques for Physiological Signal Processing. Examples of Physiological Signal Processing. Principles of Biomechanics. Practical Applications of Biomechanics. Biomaterials. Principles of Biomedical Capstone Design. Unmet Clinical Needs.

Entrepreneurship: Reasons why Most Good Designs Never Get to Market. An Engineering Solution in Search of a Biomedical Problem to Solve. Tissue Engineering. Future Trends in BME.

Bestseller

Basic Transport Phenomena in Biomedical Engineering Third Edition Ronald L. Fournier University of Toledo, Ohio, USA

Exploring fundamental engineering and life science principles to uncover key concepts in biomedical engineering transport phenomena, this volume begins with a review of the basics of thermodynamics. It then examines the physical properties of body fluids and the cell membrane before moving on to topics such as properties of blood, solute transport, pharmacokinetic analysis, extracorporeal devices, tissue engineering, and bioartificial organs.

• Provides an introductory-level text for students in bioengineering, chemical engineering, mechanical engineering, and the life sciences • Presents a basic understanding and the theories of transport in biological systems and then builds on this knowledge base to show real-world applications in the development and design of artificial organs, drug delivery systems, and tissue engineering

Pedagogical Features • Includes numerous examples with a discussion of the numerical methods used to solve the problems • Contains an extensive bibliography • Supplies numerous illustrations • Includes end-of-chapter homework problems A solutions manual is available upon qualifying course adoption.

Selected Contents Introduction. A Review of Thermodynamic Concepts.

Physical Properties of the Body Fluids and the Cell Membrane. The Physical and Flow Properties of Blood. Solute Transport in Biological Systems.

Pharmacokinetic Analysis. Extracorporeal Devices.

Tissue Engineering. Bioartificial Organs.

Catalog no. K11304, August 2011, 483 pp.

ISBN: 978-1-4398-2670-6, $93.95 / £46.99 Also available as an eBook

Catalog no. K10621, May 2011, 540 pp.

ISBN: 978-1-4398-1232-7, $104.95 / £66.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

5

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 6

Bio Signals & Systems Introduction to Biomedical Engineering Technology Second Edition Laurence Street Rosedale, British Colombia, Canada

Thoroughly revised and updated, this second edition describes current technological devices, the physiological and anatomical basis of their function, their practical applications, and their common locations in hospitals.

• Covers a wider range of devices and includes an expanded section on equipment management • Describes the day-to-day work of biomedical engineering technologists using extensive examples • Provides appendices listing normal medical values, biomedical associations, test equipment manufacturers, helpful Internet resources, and more

Pedagogical Features • Offers chapter summaries and questions to aid in reader comprehension • Contains more than 360 illustrations, plus a 16-page grayscale insert with photographs of real-life equipment problems A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction. Diagnostic Devices: Part One. Diagnostic Devices: Part Two. Diagnostic Devices: Part Three. Diagnostic Imaging. Treatment Devices: Part One. Treatment Devices: Part Two. Treatment Devices: Part Three. Biomedical Engineering Technologist (BMET) Work. Testers and Tools.

Batteries, Radiation, and Computers. Technology Management. Appendix A: Normal Values. Appendix B: Regulations and Standards. Appendix C: Biomedical Engineering Technology Programs in the United States and Canada. Appendix D: Biomedical Associations. Appendix E: Devices and Manufacturers. Appendix F: Test Equipment Manufacturers. Appendix G: Bibliography and Internet Resources.

Biology for Engineers Arthur T. Johnson University of Maryland, College Park, USA

Introducing the field of biology to today’s engineering students, this entry-level text minimizes unnecessary memorization of connections and classifications and emphasizes concepts, technology, and the utilization of living things. Filled with practical examples, it discusses biological responses from the perspectives of psychology, human factors, genetics, plant and animal physiology, imaging, control systems, actuary, and medicine. Classroom-tested at the University of Maryland, this text introduces concepts and terminology needed to understand more advanced biology literature.

• Explores areas in physics, chemistry, mathematics, and engineering relating to biology • Examines the differences between biological engineering and biological science • Includes a chapter on scaling relations showing how size effects other physical characteristics • Surveys a broad range of application areas

Pedagogical Features • Includes practical examples • Supplies end-of-chapter questions to test comprehension A solutions manual is available upon qualifying course adoption.

Selected Contents Introduction: Introduction. Principles from the Sciences: Principles of Physics. Principles of Chemistry. Principles of Mathematics and Engineering Sciences. Principles of Biology.

Responses of Living Systems: Biological Responses in Context. Scaling Factors: Allometric Relationships from Evolutionary Pressure. Utilizing Living Systems: Systems Approach. Appendices. References.

Catalog no. 77635, September 2010, 775 pp.

ISBN: 978-1-4200-7763-6, $109.95 / £69.99 Also available as an eBook

Catalog no. K12781, October 2011, 391 pp.

ISBN: 978-1-4398-6058-8, $93.95 / £59.99 Also available as an eBook

6

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 7

Biomechanics

New

Fundamentals of Biomechanics Ronald L. Huston University of Cincinnati, Ohio, USA

"... thorough and easy-to-understand ... I am happy to see an emphasis on the fundamentals of biodynamic modeling and the development of human body models. This should allow readers to more quickly understand and develop models associated with human motion. Huston is a skilled author with the ability to render difficult topics manageable."

—James W. Kamman, Western Michigan University, USA

"... gets away from the statics concepts that are quite abundant and dominant topics in previous published biomechanics books and instead focuses on motion, dynamics, and current and practical problems that are relevant to gait analysis, and human joint dynamics. The examples are vivid, intuitive, interesting and are the product of the author’s rich and exemplary many years of research and teaching."

—Farid Amirouche, University of Illinois at Chicago, USA

“Derivations of equations and formulae in this book were clear and that should be helpful for readers.

The various chapters contain problems for readers studying the subject for the first time, and for those seeking additional expertise and/or review. Overall I commend the author for writing the text and I trust that it will be a good addition to the university and engineering libraries."

—C.Q. Liu, Chrysler LLC, Troy, Michigan

This textbook provides a comprehensive survey of how the principles of mechanics are applied to human systems and organs.

Selected Contents Introduction Review of Human Anatomy and Some Basic Terminology Methods of Analysis I: Review of Vectors, Dyadics, Matrices, and Determinants Methods of Analysis II: Forces and Force Systems Methods of Analysis III: Mechanics of Materials Methods of Analysis IV: Modeling of Biosystems Tissue Biomechanics Kinematical Preliminaries: Fundamental Equations Kinematic Preliminaries: Inertia Force Considerations Human Body Inertia Properties Kinematics of Human Body Models Kinetics of Human Body Models Dynamics of Human Body Models Numerical Methods Simulations and Applications Appendix: Anthropometric Data Tables Glossary Bibliography Catalog no. K14776, April 2013, 470 pp.

ISBN: 978-1-4665-1037-1, $99.95 / £63.99 Also available as an eBook

Pedagogical Features • Includes an extensive glossary and references in each chapter • Presents illustrations and tables for clarification • Provides end-of-chapter problems and examples to test assimilation A solutions manual and figure slides are available upon qualifying course adoption.

For more information and complete contents, visit www.crctextbooks.com

7

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 8

Biomechanics Biofluid Mechanics

Biomechanics of the Upper Limbs

The Human Circulation, Second Edition Krishnan B. Chandran

Mechanics, Modeling and Musculoskeletal Injuries, Second Edition

University of Iowa, Iowa City, USA

Andris Freivalds

Ajit P. Yoganathan

The Pennsylvania State University, University Park, USA

Georgia Institute of Technology, Atlanta, USA

Stanley E. Rittgers University of Akron, Ohio, USA

"... provides a good platform in fluid mechanics prior to progressing to the physiological applications which make it an appropriate textbook for BME students."

—Professor Tim McGloughlin, Centre for Applied Biomedical Engineering Research and Department of Mechanical Aeronautical and Biomedical Engineering, University of Limerick, Ireland

This classroom-tested text teaches students how fluid mechanics is applied to the study of the human circulatory system.

Over the past two decades, the growth in computerrelated jobs has led to considerable increase in the number of work-related musculoskeletal disorders in the upper limbs. Now in its second edition, this comprehensive text is expanded to include recent findings regarding job stressors and a variety of ergonomic solutions. It provides research on the biomechanics of the upper limbs and the mechanics of neuromuscular systems. It also covers risk factors for various disorders and tools used to identify their causes.

Pedagogical Features

New to the Second Edition

• Provides numerous examples in each chapter

• Improved figures and additional examples

• Features downloadable PowerPoint® slides, sample exams, and other background material on a supporting website

• More end-of-chapter problems • A chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas

Pedagogical Features

• Contains end-of-chapter references to enhance further study A solutions manual and figure slides are available upon qualifying course adoption.

• Includes end-of-chapter problems

Selected Contents

• Contains numerous figures selected from the publications of many eminent researchers

Introduction to Biomechanics

A solutions manual and figure slides are available upon qualifying course adoption.

Structure of the Musculoskeletal System Neuromuscular Physiology and Motor Control

Selected Contents

Modeling of Muscle Mechanics

Fluid and Solid Mechanics and Cardiovascular Physiology: Fundamentals of Fluid Mechanics.

Introduction to Solid Mechanics. Cardiovascular Physiology. Biomechanics of the Human Circulation: Rheology of Blood and Vascular Mechanics. Static and Steady Flow Models. Unsteady Flow and Nonuniform Geometric Models. Native Heart Valves.

Cardiovascular Implants, Biomechanical Measurements, and Computational Simulations: Prosthetic Heart Valve Dynamics. Vascular Therapeutic Techniques. Fluid Dynamic Measurement Techniques. Computational Fluid Dynamic Analysis of the Human Circulation.

Musculoskeletal Disorders and Risk Factors

Models of the Upper Limbs Instrumentation Job and Worksite Analysis Hand Tools The Office Environment Catalog no. 91190, February 2011, 564 pp.

ISBN: 978-1-4200-9119-9, $125.95 / £79.99 Also available as an eBook

Catalog no. K12006, February 2012, 451 pp.

ISBN: 978-1-4398-4516-5, $104.95 / £66.99 Also available as an eBook

8

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 9

Biomechanics Biomechanics and Exercise Physiology Quantitative Modeling Arthur T. Johnson

Bio MEMS, NEMS & Materials New

Regenerative Engineering Edited by

Cato T. Laurencin and Yusuf Khan

University of Maryland, College Park, USA

University of Connecticut Health Center, Farmington, USA

Using numerous worked examples to demonstrate what and when to calculate, this text covers more than just the fundamentals of exercise physiology, it demonstrates the vast amount of physiological material that can be quantitatively predicted and describes how to translate this information into applications.

With an emphasis on quantitative description, it includes tables and illustrations which make this book helpful for estimating magnitudes, determining trends, and illustrating concepts.

"This book gives historical precedence for tissue engineering while providing the most up-to-date clinical examples. It is nice to see tissue engineering strategies that are tissue specific, as the design requirements of clinical solutions will depend largely on the tissue of interest. This book is ideal for introductory coursework or reference for the initiate in the field of tissue engineering. … The authors are leaders in their respective fields and have knowledge of both the breadth and depth of tissue engineering strategies. The text is well organized and will fit well into most introductory biomaterials/tissue engineering courses around the country."

Selected Contents Exercise Limitations. Exercise Biomechanics.

Cardiovascular Responses. Respiratory Responses.

Thermal Responses.

Catalog no. DK5813, March 2007, 688 pp.

ISBN: 978-1-57444-906-8, $145.95 / £93.00 Also available as an eBook

Biofluid Dynamics Principles and Selected Applications Clement Kleinstreuer North Carolina State University, Raleigh, USA

This book builds a solid understanding of medical implants and devices from a bioengineering standpoint.

The text features extensive worked examples, exercises and project assignments to stimulate critical thinking and build problem-solving skills, computer simulations of biofluid dynamics processes and medical device operations, tools for solving basic biofluid problems, and more.

A solutions manual is available upon qualifying course adoption.

Selected Contents Elements of Continuum Mechanics. Biofluid Dynamics Concepts. Analyses of Arterial Diseases.

Biofluid Mechanics of Organ Systems. Case Studies in Biofluid Dynamics. Appendices.

Catalog no. 2221, April 2006, 528 pp.

ISBN: 978-0-8493-2221-1, $119.95 / £77.99 Also available as an eBook

—Laura Suggs, University of Texas at Austin

This book integrates regenerative medicine and tissue engineering, presenting each concept in the framework of regenerative engineering. Through the combination of fundamental lecture-based teaching and problem-based learning approaches, it is the goal of this textbook to develop students into future researchers capable of completing the translation of their work from the benchtop to the bedside.

Pedagogical Features • Includes examples, case studies, and extensive references A problems-and-solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Regenerative Engineering: The Future of Medicine.

Cell Biology. Stem Cells and Tissue Regeneration.

Introduction to Materials Science. Biomaterials. In Vitro Assessment of Cell–Biomaterial Interactions.

Host Response to Biomaterials and Its Implications in Regenerative Engineering. Organ Regenerative Engineering: Cell Sources, Considerations, and Strategies. Cardiovascular Regenerative Engineering.

Bone Regenerative Engineering. Engineering Tissueto-Tissue Interfaces. Neural Regenerative Engineering. Ligament Regenerative Engineering.

Skeletal Muscle Regenerative Engineering.

Engineering Limb Regeneration: Lessons from Animals That Can Regenerate.

Catalog no. K10724, June 2013, 435 pp.

ISBN: 978-1-4398-1412-3, $99.95 / £63.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

9

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 10

Bio MEMS, NEMS & Materials Textbooks for Your Biomaterials Lectures and Lab Courses

An Introduction to Biomaterials Second Edition

A Laboratory Course in Biomaterials

Edited by

Wujing Xian

Jeffrey O. Hollinger

University of Illinois at UrbanaChampaign, USA

Carnegie Mellon University, Pittsburgh, Pennsylvania, USA

Series: Biomedical Engineering

The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date educational framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living system into which it is implanted.

• Covers wound healing biology and host response to implanted biomaterials • Examines the regulatory process, including standardized product testing

A teaching tool for instructors in biomaterials and bioengineering, this volume is a comprehensive laboratory textbook. It trains readers in laboratory skills, data analysis, problem solving, and scientific writing. It integrates a variety of principles that include materials science, chemistry, biochemistry, molecular and cell biology, and engineering. Providing detailed descriptions, explanations, and illustrations of experiments, the text also includes a series of questions and answers at the end of each chapter to clarify concepts.

Pedagogical Features

• Reviews the innovativeness of biomaterials, with inventorship and patents in mind

• Presents detailed, step-by-step descriptions of lab procedures and explanations for the underlying principles

• Considers experimental design, basic scientific methods, and statistics

• Contains user-friendly graphic illustrations for the experiments

Pedagogical Features

• Provides end-of-chapter questions and answers to clarify concepts and induce critical thinking

• Contains end-of-chapter questions and answers • Includes extensive references for further study An instructor's manual and figure slides are available upon qualifying course adoption.

Selected Contents Consensus Definitions, Fundamental Concepts, and a Standardized Approach to Applied Biomaterials Sciences. Biology, Biomechanics, Biomaterial Interactions: Wound Healing Biology. Biology, Biomechanics, Biomaterial Interactions: Cellular Mechanics. Biology, Biomechanics, Biomaterial Interactions: Materials–Host Interactions. Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Standardized Materials Testing.

Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Statistics.

Biomaterials Compositions. Biomaterials Applications.

Catalog no. K10637, November 2011, 644 pp.

ISBN: 978-1-4398-1256-3, $119.95 / £49.99 Also available as an eBook

• Includes text boxes with in-depth information, case studies, and lab tips • Offers information on equipment, reagents, and supplies for instructors

Selected Contents Basic Laboratory Skills Module I: Drug Delivery: Controlled Release of Encapsulated Protein from PLGA Microspheres Module II: Natural Biomaterials: Collagen and Chitosan Basic Laboratory Skills II: Cell Culture and Microscopy Module III: Biocompatibility Testing: Cytotoxicity and Adhesion Module IV: Tissue Engineering: Organotypic Cultures of Skin Equivalents Module V: Bioceramics: Porous Hydroxyapatite Composite Appendix: Answers Catalog no. 75829, June 2009, 216 pp., Soft Cover ISBN: 978-1-4200-7582-3, $67.95 / £43.99 Also available as an eBook

10

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 11

Bio MEMS, NEMS & Materials A Laboratory Course in Tissue Engineering Melissa Kurtis Micou University of California, San Diego, USA

Dawn Kilkenny University of Toronto, Ontario, Canada

"… an excellent handbook for graduate students and investigators who are new in tissue engineering area."

—Sha Jin, University of Arkansas, Fayetteville, USA

"… has a protocol-like style and can actually be used directly by teachers to prepare lab courses … provides students with good insight in methods, techniques, and approaches ..."

—Gerjo J.V.M. van Osch, Erasmus MC, University Medical Center Rotterdam, the Netherlands

A hands-on lab manual, this textbook contains 15 experiments based on classic and modern approaches.

Pedagogical Features • Contains 15 standalone experiments, allowing instructors to customize their courses • Provides prelab and postlab questions for each experiment A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Getting Started in the Lab. Lab Safety. Essential Lab Skills for Tissue Engineers. Isolation of Primary Chondrocytes from Bovine Articular Cartilage.

Measuring and Modeling Growth of a Cell Population. Purification of a Cell Population Using Magnetic Cell Sorting. Decellularized Matrices for Tissue Engineering. Effect of Plating Density on Cell Adhesion to Varied Culture Matrices. Dynamic versus Static Seeding of Cells onto Biomaterial Scaffolds.

Cell Patterning Using Microcontact Printing.

Measuring and Modeling the Motility of a Cell Population Using an Under-Agarose Assay.

Characterizing Matrix Remodeling Through Collagen Gel Contraction. Effect of Substrate Stiffness on Cell Differentiation. Effect of Culture Configuration (Two versus Three Dimensions) on Matrix Accumulation.

Combining In Silico and In Vitro Techniques to Engineer Pluripotent Stem Cell Fate. The FahraeusLindqvist Effect: Using Microchannels to Observe Small Vessel Hemodynamics. ...

Catalog no. K13694, August 2012, 304 pp.

Soft Cover, ISBN: 978-1-4398-7893-4 $59.95 / £38.99 Also available as an eBook

Introduction to BioMEMS Albert Folch University of Washington, Seattle, USA

"... an excellent balance of detailed descriptions and engaging visuals … well-suited for students from a variety of backgrounds, as it does a brilliant job of explaining fundamental concepts and ideas. … a valuable resource for instructors, as it contains practical exercises, tips for exams, and many sections that lend themselves to interesting classroom discussions. … should be considered required reading ...

It can serve as the bible in the field."

—Tony Jun Huang, The Pennsylvania State University, Microscopy and Microanalysis, 2013

"The field has been waiting for a true textbook that provides a practical, historical, authoritative, and comprehensive introduction to bioMEMS. It has finally arrived ..."

—David J. Beebe, University of Wisconsin–Madison, USA

"A comprehensive, colorful textbook on the important field of bioMEMS." —Albert van den Berg, University of Twente, The Netherlands

"... an outstanding text for advanced undergraduates and graduate students ..."

—Dr. Fawwaz Habbal, Harvard University, USA

"... very accessible and clear …"

—Professor Karen C. Cheung, University of British Columbia, Canada

This classroom-tested book—in color throughout— covers the whole breadth of this dynamic field.

Pedagogical Features • Highlights fundamental concepts and defines them in an extensive glossary • Includes over 400 color figures, problem sets, design challenges, and key references • Offers downloadable PowerPoint® slides for instructors An instructor's manual is available upon qualifying course adoption.

Selected Contents How Do We Make Small Things? Micropatterning of Substrates and Cells. Microfluidics. Molecular Biology on a Chip. Cell-Based Chips for Biotechnology.

BioMEMS for Cell Biology. Tissue Microengineering.

Implantable Microdevices. Appendix.

Catalog no. K10966, August 2012, 528 pp.

ISBN: 978-1-4398-1839-8, $89.95 / £57.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

11

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 12

Bio MEMS, NEMS & Materials BioMEMS From MEMS to Bio-MEMS and Bio-NEMS Manufacturing Techniques and Applications Marc J. Madou University of California, Irvine, USA

This book details manufacturing techniques applicable to bio-nanotechnology.

• Focuses on applications of NEMS and MEMS • Covers scaling laws, actuators, and fluidics • Discusses top-down and bottom-up manufacturing methods • Explains how to use nature as a guide

Pedagogical Features • Includes end-of-chapter problems as well as worked-out problems within the text • Contains color illustrations throughout • Supplies extensive references for further reading • Provides a comprehensive glossary of terms A solutions manual, an instructor’s manual, and figure slides are available upon qualifying course adoption.

Selected Contents From Traditional Manufacturing to Nanotechnology: Nonlithography-Based (Traditional) and Lithography-Based (Nontraditional) Manufacturing Compared. Nature as an Engineering Guide: Biomimetics. Nanotechnology: Top-Down and Bottom-Up Manufacturing Approaches Compared. Packaging, Assembly, and Self-Assembly.

Selected Materials and Processes for MEMS and NEMS. Metrology and MEMS/NEMS Modeling.

Scaling Laws, Actuators, and Power and Brains in Miniature Devices: Scaling Laws. Actuators. Power and Brains in Miniature Devices.

Miniaturization Application: MEMS and NEMS Applications.

Catalog no. 5516X, June 2011, 650 pp.

ISBN: 978-1-4200-5516-0, $104.95 / £66.99 Also available as an eBook

Science and Engineering Perspectives Simona Badilescu and Muthukumaran Packirisamy Concordia University, Montreal, Quebec, Canada

Covering often overlooked areas in the field of BioMEMS, this textbook spans topics associated with biomolecules and complex biological entities, as well as subjects directly linked to the design, fabrication, and characterization of devices. Unlike other references, this book aids in the fundamental physicochemical understanding of biological processes relevant to the performance of various biosensing devices. Useful for upper-level undergraduate and graduate students enrolled in engineering programs, the book includes problems in each chapter, in addition to case studies that provide real-life examples.

• Provides a concise overview of BioMEMS principles • Incorporates modern applications • Covers fabrication techniques

Pedagogical Features • Includes examples and problems in each chapter • Offers references, review questions, and case studies to aid with reader application A solutions manual is available upon qualifying course adoption.

Selected Contents Introduction Substrate Materials Used in BioMEMS Devices Biomolecules and Complex Biological Entities: Structure and Properties Engineering of Bioactive Surfaces Methods of Study and Characterization of Surface-Modified Substrates Biosensing Fundamentals Fabrication of BioMEMS Devices Introduction to Microfluidics BioMEMS: Life Science Applications Catalog no. K10877, April 2011, 368 pp.

ISBN: 978-1-4398-1699-8, $104.95 / £66.99 Also available as an eBook

12

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 13

Bio MEMS, NEMS & Materials Biomaterials Biomedical Microsystems Ellis Meng University of Southern California, Los Angeles, USA

Written by an active researcher named one of Technology Review’s Young Innovators Under 35 Reflecting the highly interdisciplinary nature of this area, this textbook covers the fundamentals of miniaturization, biomaterials, microfabrication, and nanotechnology, along with relevant applications.

Pedagogical Features: • Includes detailed examples, laboratory exercises, and a variety of homework problems • Contains numerous illustrations of concepts, processes, and devices • Offers downloadable original images for qualifying instructors A solutions manual is available upon qualifying course adoption.

Selected Contents Introduction Evolution of MEMS. Applications of MEMS. BioMEMS Applications. MEMS Resources. ...

BioMEMS Materials Traditional MEMS and Microelectronic Materials.

Polymeric Materials for MEMS. Biomaterials.

Microfabrication Methods and Processes for BioMEMS Introduction. Microlithography. Doping.

Micromachining. Wafer Bonding, Assembly, and Packaging. Surface Treatment. ...

Microfluidics Introduction and Fluid Properties. Concepts in Microfluidics. ...

Lab-on-a-Chip or Micro Total Analysis Systems Microanalytical Systems in Chemistry and Biology. ...

Sensing and Detection Methods Sensing and Detection. Sensor Characteristics.

Principles of Physical Sensing. ...

Applications to Cells, Nucleic Acids, and Proteins Cells. Nucleic Acids. Proteins.

Clinical Monitoring Flow Cytometry. Microdialysis. ...

MEMS Implants and Bioelectric Interfaces Implantable MEMS. Microelectrodes and Neural Probes. Implantable Sensors. Drug Delivery. ...

Chapters include end-of-chapter problems and references.

A Nano Approach Seeram Ramakrishna, Murugan Ramalingam, T.S. Sampath Kumar, and Winston O. Soboyejo From a multi-disciplinary point of view, this book examines basic concepts, various processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications.

Pedagogical Features: • Presents case studies that demonstrate the vital role of nanobiomaterials • Includes exercises, illustrative examples, and useful tables Figure slides are available upon qualifying course adoption.

Selected Contents Overview of Biomaterials Introduction. Biomaterials: From Then to Now. Impact of Biomaterials. ...

Basics of Human Biology Introduction. Structure and Function of the Human Body. Chemical Level. Cellular Level. ...

Degradation and Corrosion of Biomaterials Introduction. Surface Properties. ...

Failure and Tribology of Biomaterials Introduction. Deformation Mechanics.

Deformation Analysis of Biomaterials.

Fracture Mechanics. Classification of Fracture. ...

Nanoscale Phenomena Introduction. Nanoscale Phenomena.

Processing of Nanostructured Materials. ...

Metallic Biomaterials Introduction. Metallic Biomaterials.

Nanostructured Metallic Implants. Case Study.

Ceramic Biomaterials Introduction. Bioceramics.

Nanostructured Bioceramics. ...

Polymeric Biomaterials Introduction. Polymers as Biomaterials.

Classification of Polymeric Biomaterials. ...

Composite Biomaterials Introduction. Classification of Composite Biomaterials. Biological Responses to Composite Biomaterials. ...

Nanobiomaterials for Tissue Regeneration Introduction. Concept of Tissue Engineering.

The Promise of Stem Cells. ...

Chapters include a summary, glossary, and references.

Catalog no. 51229, September 2010, 408 pp.

ISBN: 978-1-4200-5122-3, $99.95 / £62.99

Catalog no. 47817, June 2010, 372 pp.

ISBN: 978-1-4200-4781-3, $104.95 / £73.99

Also available as an eBook

Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

13

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 14

Bio MEMS, NEMS & Materials Understanding Nanomedicine An Introductory Textbook Rob Burgess Medical Nanotechnologies Incorporated, Richardson, Texas, USA

Bestseller

Design of Biomedical Devices and Systems Second Edition Paul H. King

"... a comprehensive effort to introduce the diverse field of nanomedicine to students. I know of nothing else like it on the market."

Vanderbilt University, Nashville, Tennessee, USA

—Prof. Rockford K. Draper, University of Texas at Dallas, USA

This second edition of a bestseller provides an overview of biomedical device and system design from a strong design perspective.

“In a single book, Dr. Burgess has done an excellent job in providing the much-needed background in the numerous physical, chemical, and biological methods that are used to enable nanomedicine. This book will be a useful reference for any student in the field of nanomedicine and describes many examples where nanotechnology promises to improve the diagnosis, monitoring, and treatment of disease" —Dr. Gareth Hughes, Medical Nanotechnologies, Inc., USA

This book comprehensively covers a broad range of therapeutic and diagnostic applications of nanotechnology, providing descriptions of cutting-edge discoveries along with historical perspectives. The text focuses on nanomaterials and nanoparticles, the sectors that hold the most promise for the future of medicine.

Richard C. Fries ISORel, Inc., Fitchburg, Wisconsin, USA

• Provides comprehensive coverage of all major design principles • Includes updates to every chapter • Emphasizes a practical, hands-on approach to device design • Introduces the need for documentation techniques and requirements in the generation of a design team • Discusses the legal ramifications of medical device development and failure • Gives a summary of key ways to protect intellectual property

• Addresses recent findings and intriguing possibilities in nanomedicine, drawing on real data and published research from the medical sciences

• Captures snapshots of popular design areas, present and future

• Covers the historical evolution of nanotechnology

• Contains a variety of open-ended design problems and examples • Supplies detailed photographs and illustrations within each chapter • Includes nine case studies

• Looks at how nanotechnology can impact major areas of medicine, including cancer treatment, clinical neuroscience, tissue engineering, drug delivery, and diagnostics • Discusses the worldwide governmental regulatory impact on nanomedicine

Selected Contents

Pedagogical Features

A solutions manual is available upon qualifying course adoption.

Selected Contents

Fundamentals of Nanotechnology Nanoparticles and Hyperthermic Cancer Therapeutics Nanofiber-Based Scaffolds and Tissue Engineering Nanotechnology and Neuroscience Nanotechnology and Surgery Nanomatrices for Cell Culture Nanoparticle-Based Drug Delivery Nanodiagnostics Government Influence on Nanotechnology Future Concepts in Nanomedicine

Introduction to Biomedical Engineering Design Fundamental Design Tools Design Team Management, Reporting, and Documentation Product Definition Product Documentation Product Development Hardware Development Methods and Tools Software Development Methods and Tools Human Factors Industrial Design Biomaterials and Material Testing Safety Engineering: Devices and Processes ...

Catalog no. N10477, June 2012, 524 pp.

ISBN: 978-981-4316-38-5, $149.95 / £95.00

Catalog no. 61798, August 2008, 424 pp.

ISBN: 978-1-4200-6179-6, $129.95 / £82.99

Also available as an eBook

Also available as an eBook

14

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 15

Biomedical Imaging New

Clark's Essential Physics in Imaging for Radiographers Ken Holmes and Phil Harris University of Cumbria, UK

Marcus Elkington Sheffield Hallam University, UK

An invaluable tool for students, assistant practitioners, and radiographers, this reader-friendly book provides a comprehensive guide to the subject in an accessible style, with diagrams and photographs to support the text. The text opens with chapters giving an overview of image production, and basic mathematics and physics relevant to medical imaging. This section is followed by detailed chapters on physics relevant to producing diagnostic images using x-rays. Each chapter has clear learning objectives and a series of multiple-choice questions to test reader assimilation.

• Offers a practical hands-on guide for the study of physics in imaging for radiographers • Supports the understanding of fundamental definitions of physics and how these are applied to radiography

Pedagogical Features • Presents diagrams and photographs • Includes learning objectives and questions to test reader assimilation

Selected Contents Overview of Image Production Mathematics for Medical Imaging Physics for Medical Imaging X-Rays, X-Ray Circuit, and X-Ray Tube X-Ray Interactions Principles of Radiation Detection and Image Formation Image Quality Radiation Dose and Exposure Indicators Image Display and Manipulation in Medical Imaging Radiation Protection and Safety Risk–Benefit Catalog no. K18088, August 2013, 208 pp.

Soft Cover, ISBN: 978-1-4441-4561-8 $31.95 / £19.99 Also available as an eBook

Webb's Physics of Medical Imaging Second Edition Edited by

M.A. Flower Institute of Cancer Research/Royal Marsden NHS Foundation Trust, UK

Series in Medical Physics and Biomedical Engineering

"Possibly the most comprehensive book on the subject currently on the market."

—Dr. Sandro Olivo, University College London, UK

Praise for the First Edition: “For all those requiring a comprehensive review of medical imaging techniques, at a fairly basic level, this text is highly recommended.”

—Australian Physicist

This comprehensive second edition of a bestseller presents the basic physics, modern technology, and up-to-date examples of clinical application across all the modalities of medical imaging. It now covers state-of-the-art detector technology and computer processing used in medical imaging. Along with many new examples and figures, this edition includes new chapters on medical image processing and multimodality imaging.

Pedagogical Features • Provides many examples of clinical applications of medical imaging • Contains more than 400 high-quality figures, with some in color

Selected Contents In the Beginning: The Origins of Medical Imaging Diagnostic Radiology with X-Rays X-Ray Transmission Computed Tomography Clinical Applications of X-Ray Computed Tomography in Radiotherapy Planning Radioisotope Imaging Diagnostic Ultrasound Spatially Localised Magnetic Resonance Physical Aspects of Infrared Imaging Imaging of Tissue Electrical Impedance Optical Imaging Mathematics of Image Formation and Image Processing Medical Image Processing Perception and Interpretation of Images Computer Requirements of Imaging Systems Multimodality Imaging Epilogue Catalog no. IP743, June 2012, 864 pp.

ISBN: 978-0-7503-0573-0, $89.95 / £49.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

15

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 16

Biomedical Imaging Biomedical Signal and Image Processing Second Edition Kayvan Najarian and Robert Splinter "The authors’ ability to introduce concepts at the level appropriate for senior undergraduate or graduate-level students is impressive."

—Shahram Shirani, McMaster University, Hamilton, Ontario, Canada

"… an excellent bridge between the physiological significance of the methods, and the underlying mathematics."

—Dr. Kristian Sandberg, Computational Solutions, Inc., Boulder, Colorado, USA A solutions manual is available upon qualifying course adoption, and figures for presentations are available from the book's web page.

Selected Contents Introduction to Digital Signal and Image Processing.

Processing of Biomedical Signals. Processing of Biomedical Images. Related Titles.

Catalog no. K13235, May 2012, 411 pp.

ISBN: 978-1-4398-7033-4, $99.95 / £63.99

New

Practical Ultrasound An Illustrated Guide, Second Edition Jane Alty Leeds Teaching Hospitals NHS Trust and University of Leeds, UK

Edward Hoey Heart of England NHS Foundation Trust and University of Birmingham, UK

"... your pathway to achieving the competence that you desire will be made considerably easier by this book."

—Henry C. Irving FRCR, Consultant Radiologist, St James’s University Hospital, Leeds, UK; Ex-Treasurer of The Royal College of Radiologists Figure slides are available upon qualifying course adoption.

Selected Contents General Principles of Ultrasound Scanning. Guide to Using the Ultrasound Machine. Abdomen. Renal, Including Renal Transplant. Abdominal Aorta. Liver Transplant. Testes. Lower Limb Veins. Carotid Doppler Examination. Female Pelvis. Early Pregnancy.

Thyroid. Focused Assessment with Sonography in Trauma (FAST). Breast. Musculoskeletal Ultrasound.

Catalog no. K17225, July 2013, 295 pp., Soft Cover ISBN: 978-1-4441-6829-7, $79.95 / £49.99

Also available as an eBook

New

Applied Medical Image Processing

Introduction to Nuclear Science

A Basic Course

Second Edition

Wolfgang Birkfellner

Jeff C. Bryan

“Students who take a course where this book is used as the course text will be fortunate indeed.”

—William Hendee, Medical Physics, Vol. 37, Dec 2010

“... a perfect blend of theory and practice.”

—Dr. Pascal Fallavollita, Technische Universität München, Germany

University of Wisconsin –La Crosse, USA

This new edition of a bestseller provides a clear and complete introduction to nuclear chemistry and physics.

A solutions manual is available upon qualifying course adoption.

Selected Contents

A Few Basics of Medical Image Sources. Image Representation. Operations in Intensity Space.

Segmentation. Filtering and Transformations. Spatial Transforms. ...

Introduction. Mathematics of Radioactive Decay.

Energy and the Nucleus. Applications of Nuclear Science I: Power and Weapons. Radioactive Decay: The Gory Details. Interactions of Ionizing Radiation with Matter. Detection of Ionizing Radiation.

Applications of Nuclear Science II: Medicine and Food. Nuclear Reactions. Fission and Fusion.

Applications of Nuclear Science III: More about Nuclear Reactors. Radiation Protection. X-ray Production. Dosimetry of Radiation Fields. ...

Catalog no. K11176, September 2010, 403 pp.

ISBN: 978-1-4398-2444-3, $76.95 / £48.99

Catalog no. K14329, March 2013, 420 pp.

ISBN: 978-1-4398-9892-5, $89.95 / £57.99

Also available as an eBook

Also available as an eBook

Using real medical images and techniques, this book provides a truly introductory guide to medical image processing.

Selected Contents

16

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 17

Biophysics Ultrasonic and Electromagnetic NDE for Structure and Material Characterization

Physical Chemistry for Engineering and Applied Sciences

Engineering and Biomedical Applications

This book is the result of more than 30 years of teaching by the author of a one-semester course in physical chemistry to first-year students at the University of Toronto.

Edited by

Tribikram Kundu

Frank R. Foulkes

The University of Arizona, Tucson, USA

“... provides a comprehensive and rigorous approach of the fundamentals [and] enough advanced engineering and biological applications to make the reader familiar with these technologies ... an excellent text for a senior/first-year graduate course in nondestructive testing and evaluation, or as a text in a course in engineering and biological materials characterization.”

—Henrique Reis, University of Illinois at Urbana-Champaign, USA

“... an essential reference for researchers and graduate students ... chapters contributed by recognized experts in the field cover both fundamental theory as well as current research areas.”

—Dr. Paul Fromme, University College London, UK

Most books on NDE focus either on the theoretical background or on advanced applications. Bridging the gap, this book brings together principles, equations, and applications in a single, authoritative resource.

A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Things You Should Know But Probably Forgot. States of Matter and the Properties of Gases. The Ideal Gas. The Kinetic Theory of Gases. Real Gases.

Thermodynamics. Chemical Equilibrium. Phase Equilibrium. Mixtures. Colligative Properties. Ionic Equilibrium. Acid and Base Dissociation. Bases and Their Salts. Buffer Solutions. Solubility Equilibria.

Oxidation-Reduction Reactions. Electrochemistry.

Chemical Reaction Kinetics. Appendices.

Catalog no. K15157, September 2012, 703 pp.

ISBN: 978-1-4665-1846-9, $89.95 / £57.99 Also available as an eBook

Pedagogical Features

New

• Includes questions, problems, and worked-out examples

Molecular Motors in Bionanotechnology

A solutions manual is available upon qualifying course adoption.

Selected Contents Mechanics of Elastic Waves and Ultrasonic Nondestructive Evaluation. Modeling of Ultrasonic Fields by Distributed Point Source Method.

Electromagnetic Nondestructive Evaluation.

Distributed Point Source Method for Imaging in Electrostatic and Electromagnetic Problems. Guided Waves for Plate and Pipe Inspection. Fundamentals and Applications of Nonlinear Ultrasonic Nondestructive Evaluation. Theory and Applications of Laser Ultrasonic Techniques. Material Characterization by Nonlinear Ultrasonic Technique.

Toward Structural Health Monitoring Solutions for Bolted Joints. Measurement of the Elastic Properties of Solids by Brillouin Spectroscopy. Theory and Applications of Scanning Acoustic Microscopy and Scanning Near-Field Acoustic Imaging. Ultrasonic Characterization of Biological Cells. ...

Keith Firman and James Youell University of Portsmouth, UK

Many techniques have evolved to study and characterize molecular motors at the single-molecule level, such as the use of molecular tweezer devices for single-molecule studies. This book describes a wide range of molecular motors, from chemical to biological. It introduces readers to the concepts and benefits of each technique and looks at structural information and how this helps understand function. The book also examines how some of these motors are being used or may be used in the future as part of a synthetic biology approach to building devices and sensors.

Figure slides are available upon qualifying course adoption.

Catalog no. K11655, June 2012, 890 pp.

ISBN: 978-1-4398-3663-7, $149.95 / £95.00

Catalog no. N10568, March 2013, 212 pp.

ISBN: 978-981-4267-02-1, $149.95 / £95.00

Also available as an eBook

Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

17

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 18

Biotechnology

Learning Bio-Micro-Nanotechnology Mel I. Mendelson Loyola Marymount University, Los Angeles, California, USA

"… a great combination of two key disciplines in the coming quarter of this century, biotechnology and nanotechnology. This will be a good guidebook for the academic adventure as well as a bible for the pioneer in the engineering and scientific field."

—Hideyuki Kanematsu, Suzuka National College of Technology, Japan

"… provides an excellent, multi-dimensional approach to learning that I have not seen in other nanotechnology textbooks. … I really like the multitude of ways the author has the students think about the material through problems, group activities, thinking exercises, etc."

—Kory Goldammer, Richland College, USA

Learning Bio-Micro-Nanotechnology is a primer on micro/nanotechnology that teaches the vocabulary, fundamental concepts, and applications of micro/nanotechnology in biology, chemistry, physics, engineering, electronics, computers, biomedicine, microscopy, ethics, and risks to humankind. It provides an introduction into the small world with a low fog index, emphasizing the concepts using analogies and illustrations to simplify the non-observables.

Pedagogical Features • Highlights ethics case studies • Emphasizes learning with thinking exercises, analogies, study questions using Bloom’s taxonomy, team assignments, and assessment exercises • Includes appendices with a math review and a glossary of terms A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Thinking Small and Big Bit of Technology History. Tera-to-Pico Multipliers.

Size of Things. What Is "Small Technology?"

Memory Lane in Electronics. Applications.

Biomolecules and Cells Science of Evolution. Powers of "10" Revisited.

Building a Human Cell. Biomolecules. Protein Folding. Identifying Biomolecules. Forensic Methods.

Genetic Variation: Mutations.

18

Molecular Chemistry Periodic Table. Some Chemical Definitions.

Chemical Bonding. Macromolecules.

Polymer Examples. Colloids. Solid Nanomolecules.

Bit of Physics Size Matters. Working toward the Bottom.

Definitions at the Bottom. Bottom: Energy Levels and Bonding. Benefits at the Bottom.

Engineering Bits and Bytes Electronics-on-a-Chip. Computer Applications.

Control Systems.

Seeing Small Things Human Eye. Some Microscope Definitions.

Light Microscopes. Electron Microscopes.

Nanoelectronics Computer Applications. Lithographic Tools.

Recent Chip Developments. Emerging Technology.

Bottom-Up Technology.

Microelectromechanical Systems Overview. Microsensors. Microactuators. Biochips.

Nanotechnology and Cancer What Is Cancer? Discovery: L. Detection: I. Delivery: T. Destruction: R. Risks: Nano or Mega?

Bit of Anatomy. Definitions Relating to Risk.

Chemical and Physical Factors. Benefits versus Risks.

Risk Assessment. Risk Management.

Ethics and Social Relevance Some Ethics Definitions. Ethics Algorithm.

Some Ethical Issues.

Self-Assembled Future Definition: Self-Assembled Future. Geometric Proportions. Chemical Assembly. Snow Flake Assembly. Self-Assembled Colloids. Linear-Step Assembly. Spiral-Step Assembly. Amphiphilic Structures. Biomolecular Assembly. ...

Appendices Chapters include an introduction, key concepts, questions and problems, and references.

Catalog no. 82035, January 2013, 611 pp.

ISBN: 978-1-4200-8203-6, $89.95 / £57.99 Also available as an eBook

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 19

Biotechnology

Introduction to Instrumentation in Life Sciences Prakash Singh Bisen Defense Research & Development Establishment, Gwalior, India

Anjana Sharma Rani Durgavati University, Jabalpur, India

"The proposed book is an excellent one for use of students, research scholars and teachers of life sciences, biotechnology, biochemistry, biophysics, and other related disciplines where such books exclusively dedicated for life sciences are not available."

—Prof. Sukh Mahendra Singh, Coordinator, School of Biotechnology, Banaras Hindu University, India

"A comprehensive textbook on instrumentation methods which covers all major topics including practical exercises representing the syllabi of various postgraduate and undergraduate programmes in life sciences."

—Prof. Vinay Sharma, Professor and Head, Department of Bioscience and Biotechnology, Banasthali University, India

Addressing aspects of instrumentation that hold the keys for cutting-edge research and innovative applications, this book is designed to serve a wide range of students and researchers in diversified fields of life sciences, including pharmacy, biotechnology, microbiology, biochemistry, and environmental sciences.

• Provides a comprehensive overview of techniques and usage of key instrumentation • Includes basic theoretical and practical details for numerous types of chromatography • Describes a broad range of spectroscopic techniques • Covers electrophoretic techniques and their applications for deciphering the molecular nature of cell components as well as in gene technology • Contains unique in-depth coverage of fermentation processes • Offers an excellent bench manual for researchers Figure slides are available upon qualifying course adoption.

Selected Contents Microscopy Magnification, Resolution, and Contrast. Light (Bright Field) Microscopy. Dark Field Microscope.

Phase Contrast Microscope. Interference Microscope.

UV and Fluorescence Microscopes. Electron Microscopy. Tunneling Electron Microscopy. ...

Micrometry Structure of an Ocular Micrometer. Conjugate Image-Forming Focal Planes. Eyepiece Designs.

Stage Micrometer. Filar Eyepiece Micrometer. ...

Electrochemical Techniques Structure of a pH Meter. Principles. Factors Limiting the Accuracy of pH Measurements. Measurement of pH. Working. Procedure for Measuring pH Using a pH Meter. Cleaning and Troubleshooting of Glass Probes. Application of pH Measurements. ...

Chromatography General Principles. Column Chromatography. Paper Chromatography and Thin-Layer Chromatography.

Sample Collection, Preservation, and Preparation. ...

Spectroscopy UV–Visible Spectroscopy. IR (Vibrational) Spectroscopy. Flame/Atomic Absorption Spectroscopy. Fluorescence Spectroscopy.

ESR Spectroscopy. NMR Spectroscopy. ...

Centrifugation Principle of Centrifugation. Types of Centrifuges.

Types of Centrifugal Separations. Rotor Categories.

Selection of Centrifuge Tubes. Common Centrifugation Vocabulary and Formulas. ...

Electrophoresis Principles of GE. Working with the Electrophoresis Apparatus. Denaturing Gradient GE. Temperature Gradient GE. Pulsed-Field GE. ...

X-Ray Microanalysis Principles. Instrumentation. Applications of X-Ray Microanalysis. Techniques for the Analysis of Secondary, Tertiary, and Quaternary Proteins by X-Ray Crystallography.

Techniques with Radioisotopes Isotopes and Radioactivity. Ionization Effects.

Measurement Units. Measurement Techniques.

Autoradiography. Counting Statistics. Biological Uses of Radioisotopes. ...

Fermentation History. Principles of Fermentation. Introduction to Microorganisms. Types of Fermentation Metabolism.

Fermentation Process. Types of Fermentation. ...

Conductivity Meter Principles. Common Definitions. Conductivity Meter.

Conductivity Cells. Factors Influencing the Measurement. Measuring Techniques. ...

Glossary Chapters include an introduction, suggested readings, and important links.

Catalog no. K14893, September 2012, 383 pp.

Soft Cover, ISBN: 978-1-4665-1240-5 $79.95 / £49.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

19

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 20

Biotechnology

Biotechnology Fundamentals Firdos Alam Khan Manipal University, Dubai, UAE

The focus of Biotechnology Fundamentals is to educate readers on both classical and modern aspects of biotechnology and to expose them to a range of topics, from basic information to complex technicalities. Other books cover subjects individually, but this text offers a rare topical combination of coverage, using numerous helpful illustrations to explore the information that students and researchers need to intelligently shape their careers.

Pedagogical Features • Supplies learning objectives for each chapter • Includes problems, lab assignments, references, and ancillary online resources • Suggests field trips that can be used to apply and better understand concepts and other material in the book A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction to Biotechnology What Is Biotechnology?. Animal Biotechnology.

Agricultural Biotechnology. Medical Biotechnology.

Industrial Biotechnology. Environmental Biotechnology. ...

Genes and Genomics Introduction. Cell as the Building Block of Life.

Classification of Cells. Extracellular Organization.

Intracellular Organization. Macromolecules. Genes and Genetics. Cell Division. DNA Replication. ...

Proteins and Proteomics Introduction. Significance of Proteins. Protein Biosynthesis. Protein Structure. Protein Folding.

Protein Modification. Protein Transport. Protein Dysfunction and Degradation. ...

Recombinant DNA Technology Introduction. Making of Recombinant DNA. Significance of Recombinant DNA Technology. Role of Restriction Enzymes in rDNA Technology. Steps in Gene Cloning. ...

Microbial Biotechnology Introduction. Structural Organization of Microbes.

Microbial Metabolism. Microbial Growth. Microbial Genetics. Genetic Recombination in Bacteria.

Transposable Genetic Elements. ...

Agricultural Biotechnology Introduction. Plant Breeding. Plant Diseases.

Applications of Molecular and Genetic Tools in Agriculture. Herbicide-Tolerant Plants. Pigmentation in Transgenic Plants. Altering the Food Content of Plants. ...

20

Animal Biotechnology Introduction. History of the Use of Animals in Research. Drug Testing in Animals is Mandatory.

Application of Animal Models. ...

Environmental Biotechnology Introduction. Factors Affecting the Environment.

Environment Protection by Biotechnology.

Medical Biotechnology Introduction. Antibody Production. Therapeutic Proteins. Stem Cell Transplantation. Bioengineered Skin. Bioengineered Organ Transplantation. ...

Nanobiotechnology Introduction. Nanotechnology. Nanobiotechnology.

Applications of Nanobiotechnology. Nanotechnology in the Food Industry. ...

Product Development in Biotechnology Introduction. Methods of Scientific Enquiry.

Commercialization of Scientific Discovery. Business Plan. Biotechnology Product Development. ...

Industrial Biotechnology Introduction. Fermenter or Bioreactor. Principle of Fermentation. Production of Biomolecules Using Fermenter Technology. Development Process of Microbial Products. Upstream Bioprocess. ...

Ethics in Biotechnology Introduction. Genetically Modified Foods and Plants.

Use of Animals as Experimental Models. Use of Humans as Experimental Models. ...

Careers in Biotechnology Introduction. Education and Investment in Biotechnology. Research and Development in Biotechnology. Biotechnology Industry and Products.

Biotechnology Status in the United States. ...

Laboratory Tutorials Laboratory Experiments. Laboratory Safety. Good Laboratory Practices for Biotechnology Labs. General Laboratory Techniques. General Principles of Animal Handling. Animal Anesthesia. Animal Histology.

Blood Collection in Animals. Histology and Microscopy. Separation Techniques. Microbiology Techniques. ...

Glossary Catalog no. K11059, September 2011, 608 pp.

ISBN: 978-1-4398-2009-4, $93.95 / £49.99 Also available as an eBook

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 21

Biotechnology Biotechnology Operations Principles and Practices Michael J. Roy University of Wisconsin-Madison, USA

Applying the author's experience teaching the subject and working in both industry and government, this book introduces key biotechnology developments and covers critical elements, such as project management, regulatory affairs, quality assurance, biomanufacturing, quality control, nonclinical safety testing, and clinical evaluation.

• Provides an introduction to each key biotechnology development subject • Incorporates an integrated approach, tying together the seven key functional areas • Emphasizes the need to both plan and integrate an operations program, offering the information required to successfully lead such efforts • Uses relatively simple language, clarifies jargon, and uses diagrams to describe processes, making concepts easy to understand

Pedagogical Features • Includes practical problems and questions • Supplies a glossary A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction to Biotechnology Operations: Planning for Success Project Management Regulatory Affairs Regulatory Compliance Quality Systems Biomanufacture Quality Control Nonclinical Studies Clinical Trials Glossary Additional Reading Practical Problems and Questions Catalog no. K11486, March 2011, 416 pp.

ISBN: 978-1-4398-3027-7, $104.95 / £66.99 Also available as an eBook

Healthcare Biotechnology A Practical Guide Dimitris Dogramatzis Dogramatzis Pharmacy, Athens, Greece

"The section on marketing is also particularly strong and well thought through. ... provides insight into the biotechnology business sector."

—British Journal of Biomedical Science

This text is a practical resource to assist healthcarerelated biotech professionals in their day-to-day activities from the lab to the boardroom.

A solutions manual, instructor’s manual, and figure slides are available upon qualifying course adoption.

Selected Contents The Healthcare Biotechnology Industry. Intellectual Property. Funding. New Product Development.

Marketing. Running the Business.

Catalog no. K12108, December 2010, 689 pp.

ISBN: 978-1-4398-4746-6, $109.95 / £69.99 Also available as an eBook

Systems Biology and Bioinformatics: A Computational Approach Kayvan Najarian, Christopher N. Eichelberger, Siamak Najarian, and Shahriar Gharibzadeh This text provides a comprehensive collection of the computational methods used in what is being coined the digital era of biology.

A solutions manual is available upon qualifying course adoption.

Selected Contents Cell Biology. Bioassays. Review of Some Computational Methods. Computational Structural Biology: Protein Structure Prediction. Computational Structural Biology: Protein Sequence Analysis.

Genomics and Proteomics. Methods for Identification of Differentially Expressed Genes or Proteins. Binary and Bayesian Networks as Static Models of Regulatory Pathways. ...

Catalog no. 46500, April 2009, 190 pp.

ISBN: 978-1-4200-4650-2, $79.95 / £49.99 Also available as an eBook

For more information and complete contents, visit www.crctextbooks.com

21

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 22

General Textbooks New

Numerical Methods for Chemical Engineers Using Excel, VBA, and MATLAB®

Technical Writing A Practical Guide for Engineers and Scientists Phillip A. Laplante

Victor J. Law

The Pennsylvania State University, Malvern, USA

Tulane University, New Orleans, Louisiana, USA

Series: What Every Engineer Should Know

While teaching the Numerical Methods for Engineers course over the last 15 years, the author found a need for a new textbook, one that was less elementary, provided applications and problems better suited for chemical engineers, and contained instruction in Visual Basic® for Applications (VBA). This led to six years of developing teaching notes that have been enhanced to create the current textbook.

Written by a renowned engineer and widely published technical author, this guide enables readers to write, edit, and publish materials of a technical nature, including books, articles, reports, and electronic media.

A solutions manual and figure slides are available upon qualifying course adoption.

Catalog no. K16702, March 2013, 247 pp.

ISBN: 978-1-4665-7534-9, $59.95 / £38.99 Also available as an eBook

Selected Contents The Nature of Technical Writing. Technical Writing Basics. The Writing Process. Scientific Writing.

Business Communications. Technical Reporting.

Using Graphical Elements. Publishing Your Work.

Writing for E-Media. Writing with Collaborators.

Glossary.

Catalog no. K11106, July 2011, 250 pp., Soft Cover ISBN: 978-1-4398-2085-8, $41.95 / £26.99 Also available as an eBook

A First Course in Differential Equations, Modeling, and Simulation Carlos A. Smith and Scott W. Campbell University of South Florida, Tampa, USA

Emphasizing a practical approach, this text avoids overly theoretical explanations and shows you how differential equations are derived by applying basic physical principles and experimental observations to engineering systems.

A solutions manual and figure slides are available upon qualifying course adoption.

Selected Contents Introduction. Objects in a Gravitational Field.

Classical Solutions of Ordinary Linear Differential Equations. Laplace Transforms. Mechanical Systems: Translational. Mechanical Systems: Rotational. Mass Balances. Thermal Systems. Electrical Systems.

Numerical Simulation.

Random Phenomena Fundamentals of Probability and Statistics for Engineers Babatunde A. Ogunnaike University of Delaware, Newark, USA

“... distinguished from the crowded field by the wellexplained theory of statistics and how it provides interesting applications.”

—Walid K. Sharabati, The American Statistician, Aug 2011

“Instructors who are looking for an alternative textbook should give a serious consideration to adopting this book.”

—Ali Cinar, Technometrics, Aug 2011

“I would have loved to be taught from a book like this and I heartily recommend this book as a classroom textbook for both the clarity of the explanations and the amount of material covered.”

—Pieter Bastiaan Ober, Journal of Applied Statistics, 2011 A solutions manual is available upon qualifying course adoption.

Catalog no. K12318, May 2011, 345 pp.

ISBN: 978-1-4398-5087-9, $93.95 / £59.99

Catalog no. 44974, September 2009, 1056 pp.

ISBN: 978-1-4200-4497-3, $146.95 / £94.00

Also available as an eBook

Also available as an eBook

22

1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524 • orders@crcpress.com

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 23

✦

Ask your librarian to ✦ sign up for a FREE TRIAL

The Best Science, Technology, and Medical eBooks from CRC Press ➢ More than 11,000 references in over 350 subject areas ➢ Over 50 discipline-specific CRCnetBASEs ➢ Build your own customized CRCnetBASE ➢ Anytime, anywhere access with CRCnetBASE Mobile

CRC Press Taylor & Francis Group

www.CRCnetBASE.com

Experience the textbook evolution.

➢ Custom Publishing available

➢ Easily search for key content

➢ Access anytime, anywhere

www.crctextbooks.com

6000 Broken Sound Parkway, NW, Suite 300 Boca Raton, FL 33487, USA

HJM01_5.5x8.5_TMC_ISSUU_HJM01_5.5x8.5_TMC 8/8/13 10:35 AM Page 24