Neuroscience

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Neuroscience Books from CRC Press

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Contents Frontiers in Neuroscience & Neuroengineering ..4 Neuroanatomy/Neurophysiology ........................8 Neuroscience & Health ....................................13 Neurobiology......................................................15 Developmental Biology ......................................19 Page 14

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Neurotechnology................................................20 Neuropsychology/Neuropsychiatry ....................23 Pain Management ............................................26

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CRC Press

Taylor & Francis Group

Dear Doctor: CRC Press is a global publisher of premier books in neuroscience and related fields. In this catalog, we are pleased to present a comprehensive collection of our new and bestselling titles written by experts from around the world. Many of these traditional format books are also available digitally, so you can choose the option that best meets your needs.

Do you have an idea for a book in neurology, neuroscience or neuropsychology?

We welcome proposals for new book concepts. Please contact Senior Editor Lance Wobus at Lance.Wobus@tayloarandfrancis.com to discuss your project.

We look forward to providing you with superior references to help you with research activities and meet the desired goals of your clinical practice in 2014 and beyond.

Sincerely,

Nally Dookwah-Abrams

Marketing Manager, Medical

www.crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524

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Frontiers in Neuroscience & Neuroengineering Methods in Brain Connectivity Inference through Multivariate Time Series Analysis Edited by

Koichi Sameshima and Luiz Antonio Baccala University of São Paulo, Brazil

Interest in brain connectivity inference has become ubiquitous and is now increasingly adopted in experimental investigations of clinical, behavioral, and experimental neurosciences. Methods in Brain Connectivity Inference through Multivariate Time Series Analysis gathers the contributions of leading international authors who discuss different time series analysis approaches, providing a thorough survey of information on how brain areas effectively interact.

Incorporating multidisciplinary work in applied mathematics, statistics, and animal and human experiments at the forefront of the field, the book addresses the use of time series data in brain connectivity interference studies. Contributors present codes and data examples to back up their methodological descriptions, exploring the details of each proposed method as well as an appreciation of their merits and limitations. Supplemental material for the book, including code, data, practical examples, and color figures is supplied in the form of a CD with directories organized by chapter and instruction files with additional detail.

Itch Mechanisms and Treatment Edited by

E. Carstens and Tasuku Akiyama University of California, Davis, USA

Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer.

Composed of contributions from distinguished researchers around the world, the book explores topics such as: • Neuropathic itch • Peripheral neuronal mechanism of itch • The role of PAR-2 in neuroimmune communication and itch • Mrgprs as itch receptors • The role of interleukin-31 and oncostatin M in itch and neuroimmune communication • Spinal coding of itch and pain • Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Selected Contents:

Brain Connectivity: An Overview Fundamental Theory Directed Transfer Function: A Pioneering Concept in Connectivity Analysis An Overview of Vector Autoregressive Models Partial Directed Coherence ...

Extensions Nonlinear Parametric Granger Causality in Dynamical Networks Time-Variant Estimation of Connectivity and Kalman Filter Applications Connectivity Analysis Based on Multielectrode EEG Inversion Methods with and without fMRI a Priori Information ...

Epilogue Multivariate Time-Series Brain Connectivity: A Sum-Up Index

Itch Hypotheses: From Pattern to Specificity and to Population Coding Epidemiology of Itch Atopic Dermatitis Clinical Aspects of Itch: Psoriasis Pruritus in Renal Disease Pruritus of Cholestasis Pruritus in Cutaneous T-Cell Lymphomas Pruriceptors Toll-Like Receptors and Itch Lipid Mediators and Itch The Role of Transient Receptor Potential Channels in Acute and Chronic Itch Sensitization of Itch Signaling 2: Itch Sensitization— Nerve Growth Factor, Semaphorins Peripheral Opioids Itch Modulation by VGLUT2-Dependent Glutamate Release from Somatic Sensory Neurons Ascending Pathways for Itch The Brain Processing of Itch and Scratching ...

Catalog no. K12042, March 2014, 282 pp.

ISBN: 978-1-4398-4572-1, $159.95 / £99.00 Also available as an eBook

Catalog no. K14566, February 2014, 494 pp.

ISBN: 978-1-4665-0543-8, $159.95 / £99.00 Also available as an eBook

Selected Contents:

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Frontiers in Neuroscience & Neuroengineering New!

Coming Soon!

Humanoid Robotics and Neuroscience

Brain Neurotrauma

Edited by

Molecular, Neuropsychological, and Rehabilitation Aspects

Gordon Cheng

Edited by

ATR Computational Neuroscience Labs, Saraku-gun, Kyoto, Japan

Firas H. Kobeissy University of Florida, Gainesville, USA

Humanoid robots are highly sophisticated machines equipped with human-like sensory and motor capabilities. Today we are on the verge of a new era of rapid transformations in both science and engineering—one that brings together technological advancements in a way that will accelerate both neuroscience and robotics.

Humanoid Robotics and Neuroscience: Science, Engineering and Society presents the contributions of prominent scientists who explore key aspects of the further potential of these systems.

Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects presents the different animal models used for brain and spinal cord injuries including open head, closed, mild, moderate, and acute brain injuries. It discusses recent advances in biomarker research and examines neuropsychological and behavioral changes associated with brain trauma.

Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research.

Topics include:

Selected Contents:

• Neuroscientific research findings on dexterous robotic hand control • Humanoid vision and how understanding the structure of the human eye can lead to improvements in artificial vision • Humanoid locomotion, motor control, and the learning of motor skills • Cognitive elements of humanoid robots, including the neuroscientific aspects of imitation and development • The impact of robots on society and the potential for developing new systems and devices to benefit humans

Experimental CNS Trauma: A General Overview of Neurotrauma Research Combat TBI: History, Epidemiology and Injury Modes Neuromechanisms in Brain Injury Microglia in Experimental Brain Injury: Implications on Neuronal Injury and Circuit Remodeling ...

Management in CNS Trauma Chronic Pain in Neurotrauma: Implications on Spinal cord and Traumatic Brain Injury Characterization and Management of Headache after Mild Traumatic Brain Injury Modeling Brain Injury Controlled Cortical Impact Model Modeling Fluid Percussion Injury: Relevance to Human TBI Imaging and Biomarkers Exploring Serum Biomarkers for Mild Traumatic Brain Injury The Emerging Impact of microRNAs in Neurotrauma Pathophysiology and Therapy ...

Neurocognitive and Neurobehavioral Topics in Brain Injury Blast-Related Mild Traumatic Brain Injury: Neuropsychological Evaluation and Findings Neurorehabilitation and Neuroprotection Models of Post-Traumatic Brain Injury Neurorehabilitation Application of Novel Therapeutic Agents for CNS Injury: NAAG Peptidase Inhibitors ...

Mild Brain Injury and Sport Concussion Substance Abuse and Comorbid Conditions

Science, Engineering and Society

Selected Contents: Humanoid Robotics Perspectives to Neuroscience Humanoid Robotics and Neuroscience: Science, Engineering and Society ...

Emulating the Neuro-mechanisms with Humanoid Robots Hands, Dexterity and the Brain Humanoid Action, Recognition and the Brain: Stochastic Information Processing that Unifies Recognition and Generation of Motion Patterns Toward Symbolical Understanding of the Continuous World ...

Leaping forward: Toward Cognitive Humanoid Robots Learning from Examples: Imitation Learning Emerging Cognition ...

Catalog no. 93665, December 2014, 336 pp.

ISBN: 978-1-4200-9366-7, $99.95 / £63.99 Also available as an eBook

Catalog no. K16127, February 2015, c. 792 pp.

ISBN: 978-1-4665-6598-2, $229.95 / £146.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Frontiers in Neuroscience & Neuroengineering Spike Timing

Neuromorphic Olfaction

Mechanisms and Function

Edited by

Edited by

Patricia M. DiLorenzo Binghamton University, New York, USA

The University of Manchester, UK

Santiago Marco and Agustin Gutierrez-Galvez

Jonathan D. Victor Weill Medical College of Cornell University, New York, USA

Addressing current thinking as well as future possibilities, Spike Timing: Mechanisms and Function provides readers with a broad perspective on how spike timing is produced and used by the nervous system.

The first section describes the foundation for quantitative analysis and theory. It examines the information contained in spike timing, how it can be quantified, and how neural systems can extract it. The second section explores how input-output relationships are reflected in spike timing across a range of sensory systems.

Drawing together theoretical, computational, and experimental studies in a range of model systems, the book provides a firm background for investigators to consider spike timing as it applies to their own work.

It also offers a glimpse of future advances related to mechanisms of spike timing and its role in neural function, such as the development of novel computational technologies.

Contents: Introduction Spike Timing - Tools and Models Spike Trains as Event Sequences: Fundamental Implications Neural Coding and Decoding with Spike Times Can We Predict Every Spike? Statistical Identification of Synchronous Spiking Binless Estimation of Mutual Information in Metric Spaces Measuring Information in Spike Trains about Intrinsic Brain Signals The Role of Oscillation-Enhanced Neural Precision in Information Transmission between Brain Areas Spike Timing - Coding, Decoding and Sensation Timing Information in Insect Mechanosensory Systems Neural Encoding of Dynamic Inputs by Spike Timing Relating Spike Times to Perception – Auditory Detection and Discrimination Spike Timing and Neural Codes for Odors Spike Timing as a Mechanism for Taste Coding in the Brainstem Increases In Spike Timing Precision Improves Gustatory Discrimination Upon Learning Spike Timing in Early Stages of Visual Processing Cortical Computations Using Relative Spike Timing Catalog no. K11729, May 2013, 442 pp.

ISBN: 978-1-4398-3815-0, $149.95 / £95.00 Also available as an eBook

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Krishna C. Persaud

University of Barcelona and Institute for Bioengineering of Catalonia, Spain

Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning.

Neuromorphic Olfaction is a collaboration among European researchers who introduce novel computing paradigms and biomimetic artifacts for chemical sensing.

Developing neuromorphic olfaction from conceptual points of view to practical applications, this crossdisciplinary book examines: • The biological components of vertebrate and invertebrate chemical sensing systems • The early coding pathways in the biological olfactory system • The advantages of nonspecific receptor populations in encoding odor intensity as well as odor identity • The redundancy and the massive convergence of the olfactory receptor neurons to the olfactory bulb • A neuromorphic approach to artificial olfaction in robots • Reactive and cognitive search strategies for olfactory robots • The implementation of a computational model of the mammalian olfactory system The book’s primary focus is on translating aspects of olfaction into computationally practical algorithms.

These algorithms can help us understand the underlying behavior of the chemical senses in biological systems. They can also be translated into practical applications, such as robotic navigation and systems for uniquely detecting chemical species in a complex background.

Selected Contents: Engineering Aspects of Olfaction Study of the Coding Efficiency of Populations of Olfactory Receptor Neurons and Olfactory Glomeruli Mimicking Biological Olfaction with Very Large Chemical Arrays The Synthetic Moth: A Neuromorphic Approach toward Artificial Olfaction in Robots ...

Index Catalog no. K13286, April 2013, 238 pp.

ISBN: 978-1-4398-7171-3, $149.95 / £95.00 Also available as an eBook

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Frontiers in Neuroscience & Neuroengineering Neurobiology of Body Fluid Homeostasis

Transcranial Brain Stimulation

Transduction and Integration

Edited by

Edited by

University of Brescia and IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy

Laurival Antonio De Luca Jr. and Jose Vanderlei Menani Sao Paulo State UniversityUNESP, Araraquara, Brazil

Alan Kim Johnson University of Iowa, Iowa City, USA

A timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, São Paulo, Brazil in 2011. Broad international participation at this event generated stimulating discussion among the invited speakers, leading to the publication of Neurobiology of Body Fluid Homeostasis: Transduction and Integration.

Drawn from the proceedings and filled with rich examples of integrative neurobiology and regulatory physiology, this volume: • Provides updated research using human and animal models for the control of bodily fluids, thirst, and salt appetite • Explores neural and endocrine control of body fluid balance, arterial pressure, thermoregulation, and ingestive behavior • Discusses recent developments in molecular genetics, cell biology, and behavioral plasticity • Reviews key aspects of brain serotonin and steroid and peptide control of fluid consumption and arterial pressure The findings discussed by the learned contributors are relevant for a basic understanding of disorders such as heat injury, hypertension, and excess salt intake.

Carlo Miniussi

Walter Paulus Georg-August University of Göttingen, Germany

Paolo M. Rossini Catholic University of the Sacred Heart, Rome, Italy

Recent years have seen the introduction and rapid development of non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES).

This book reviews the wide range of possible brain stimulation applications in combination with neuroimaging and discusses what new information can be gained from using these techniques. The authors also explore the dynamics of brain functions, hierarchical organization, and effective connectivity.

Catalog no. K13512, December 2012, 465 pp.

ISBN: 978-1-4398-7570-4, $159.95 / £99.00 Also available as an eBook

Fat Detection Taste, Texture, and Post Ingestive Effects Jean-Pierre Montmayeur Centre des Sciences du Hout, Dijon, France

Johannes le Coutre

Selected Contents:

Nestlé Research Center, Lausanne, Switzerland

The Human Penchant for Deranged Salt Balance Neuroendocrinology of Hydromineral Homeostasis Diverse Roles of Angiotensin Receptor Intracellular Signaling Pathways in the Control of Water and Salt Intake Separating Thirst from Hunger Interdependent Preoptic Osmoregulatory and Thermoregulatory Mechanisms Influencing Body Fluid Balance and Heat Defense Catecholaminergic Medullary Pathways and Cardiovascular Responses to Expanded Circulating Volume and Increased Osmolarity Brain Serotonergic Receptors and Control of Fluid Intake and Cardiovascular Function in Rats ...

Taking a multidisciplinary approach, this volume sheds new light on critical concerns regarding dietary fat and its relation to obesity. Going far beyond the well-known concerns, it offers new scientific data on the many aspects of fat, including psychological, behavioral, genetic, and physiological factors that contribute to its desirability, perception, intake, and impact on human health. Bringing together cross-disciplinary research, it includes information on genetic predisposition, neural imaging, and endocrine impacts on metabolism. It also provides a progressive integrated view on fat taste, fat preference, and nutrition at the molecular level.

Catalog no. K14645, October 2013, 336 pp.

ISBN: 978-1-4665-0693-0, $139.95 / £89.00 Also available as an eBook

Catalog no. 67753, September 2009, 643 pp.

ISBN: 978-1-4200-6775-0, $169.95 / £112.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neuroanatomy / Neurophysiology New!

New!

Neuroanatomical Basis of Clinical Neurology

Neurology and Clinical Neuroanatomy on the Move

Second Edition

Matthew Tate, Johnathan Cooper-Knock, Zoe Hunter, and Elizabeth Wood

Orhan E. Arslan University of South Florida, Tampa, USA

Bridging the gap between the peripheral and central nervous systems, the second edition of Neuroanatomical Basis of Clinical Neurology enriches understanding of neurological conditions through a conceptual approach to neuronal circuitry.

The book retains the basic outline of contents from the first edition, integrating structural organization with pertinent clinical disorders, while reflecting the substantial growth and ever-changing information in neuroscience.

After an introduction to the developmental and cellular aspects of the nervous system, the book discusses in depth the morphology and internal organization of the central nervous system. It examines the somatic and autonomic components of the peripheral nervous system, emphasizing nerve entrapments and neuropathies. The author describes various dysfunctions by demonstrating the neuronal interconnectivity between higher and lower autonomic centers and the mediation of visceral reflexes.

Selected Contents: Basic Neuroanatomy Developmental Aspects of the Nervous System Basic Elements of the Nervous System Morphologic and Sectional Neuroanatomy Spinal Cord Brainstem Reticular Formation ...

Peripheral Neuroanatomy Autonomic Nervous System (ANS) Spinal Nerves Cranial Nerves Functional Neuroanatomy Neurotransmitters Special Somatic Sensations Visual System Auditory System Vestibular System Special Visceral Sensations Olfactory System Limbic System ...

General Somatic Sensations Cortical and Subcortical Sensory Systems Motor Systems Upper and Lower Motor Neuron Systems Extrapyramidal Motor System Index Catalog no. K12154, August 2014, 520 pp.

ISBN: 978-1-4398-4833-3, $79.95 / £49.99

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The Medicine on the Move series provides fully flexible access to subjects across the curriculum in a unique combination of print and mobile formats ideal for the busy medical student and junior doctor.

Neurology and Clinical Neuroanatomy on the Move provides sharply focused content equally suited to those studying the subject for the first time or revisiting it during exam preparation.

Features: • Focuses on neurology, neuroanatomy, and neurosurgery • Provides quick access to information on common neurological conditions and the underlying anatomy • Uses bulleted text, flow charts, colorful diagrams, and summary tables to display information in an accessible manner • Presents “micro-facts” that guide readers quickly to key points • Contains a self-assessment section with multiple choice questions, allowing readers to test and reinforce understanding • Includes mobile access to supplemental material

Contents: Neurological Zones Symptoms and Signs Anatomy of the Cerebral Hemispheres Basal Ganglia and Subcortical Structures Cerebrospinal Fluid (CSF) and Ventricles Brainstem and Cerebellum Vestibular System ...

Disorders of the Nervous System Cerebrovascular Disease Intracranial Neoplasms Demyelinating Disorders Dementia Seizures Headache and Facial Pain Neurocutaneous Disorders Neurological Infections ...

History and Examination History/Examination/Investigations Catalog no. K16993, December 2014, 360 pp.

Pack - Book and eBook, ISBN: 978-1-4441-3832-0 $39.95 / £24.99

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Neuroanatomy / Neurophysiology Coming Soon!

Circadian Physiology Third Edition Roberto Refinetti University of South Carolina, Columbia, USA

Biological processes that repeat themselves every 24 hours within a biological system are called circadian rhythms. The circadian clock affects the operation of practically all functions in the body. Now in its third edition, Circadian Physiology presents the latest information on recent research and clinical developments. This edition addresses molecular circadian clocks in cells of multiple organs other than the hypothalamus and the pineal gland. It also explores advances in post-translational mechanisms in the operation of the molecular clock.

Highlights of the Third Edition: • Updates all chapters in light of recent research and clinical developments • Presents new material on the characterization of photoresponsive ganglionic cells in the mammalian retina • Discusses molecular circadian clocks in cells of multiple organs • Explores advances in post-translational mechanisms in the operation of the molecular clock • Includes a summary, didactical exercises, suggestions for further reading, and related websites in each chapter • Provides free software for data analysis, tutorials, and simulations

Contents: History and Methods History of Circadian Physiology Research Methods in Circadian Physiology ...

Phenomenology Ultradian and Infradian Rhythms Daily and Circadian Rhythms Mechanisms Endogenous Mechanisms Photic Environmental Mechanisms Nonphotic Environmental Mechanisms ...

Physical Substrates Pacemakers Afference and Efference Applications Everyday-Life Applications Business Applications Medical Applications Catalog no. K15022, September 2015, c. 704 pp.

ISBN: 978-1-4665-1497-3, $139.95 / £89.00

Coming Soon!

Greenfield's Neuropathology Ninth Edition Edited by

Seth Love, Arie Perry, James Ironside, and Herbert Budka Greenfield's Neuropathology, considered by many to be the world’s leading neuropathology reference, provides an authoritative, comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations.

Underpinning the text is a clear description of the molecular and cellular processes and reactions that are relevant to the development, and normal and abnormal functioning of, the nervous system. Care has been taken to ensure that the information is accessible to readers working within a range of disciplines in the clinical neurosciences, and that the neuropathological findings are placed within the context of a broader diagnostic process.

The ninth edition features an international editorial team and the contributions of many new key opinion leaders to provide a fresh perspective. The book contains more than 4000 high-quality photographs and explanatory line diagrams, many new to this edition.

Selected Content: General Pathology of the Central Nervous System Vascular Disease, Hypoxia, and Related Conditions Disorders of the Perinatal Period Metabolic and Neurodegenerative Diseases of Childhood Mitochondrial Disorders Nutritional Disorders Trauma Neuropathology of Epilepsy Degenerative Ataxic Disorders Motor Neuron Disorders Psychiatric Diseases Prion Diseases Viral Infections Bacterial Infections Parasitic Diseases Fungal Infections Demyelinating Diseases Diseases of Peripheral Nerve Diseases of Skeletal Muscle Tumours Catalog no. K17413, February 2015, c. 2456 pp.

Pack - Book and eBook, ISBN: 978-1-4441-6693-4 $879.00 / £560.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neuroanatomy / Neurophysiology Coming Soon!

Atlas of Functional Neuroanatomy Third Edition

Neurophysiology A Conceptual Approach, Fifth Edition Roger Carpenter

Walter Hendelman, M.D.

Gonville and Caius College, Cambridge, UK

University of Ottawa, Ontario, Canada

Benjamin Reddi

Presenting a clear visual guide to understanding the human central nervous system (CNS), the Atlas of Functional Neuroanatomy, Third Edition presents text accompanying each illustration to help readers gain a full understanding of the human CNS from a functional perspective.

The core information includes an overview of the CNS, sensory, and motor functional systems, and a detailed look at microanatomy. This new edition provides a more global introductory section, an upgrade of the illustrations and the neuroimaging (CT and MRI), revision to illustrations, and clinical problems and answers. The book includes a glossary and readers have access to an author-sponsored website with illustrations and animation.

Selected Contents: Orientation Spinal Cord Brainstem And Cranial Nerves Diencephalon (Thalamus) Cerebral Hemispheres Ventricles And CSF Basal Ganglia Internal Capsule Functional Systems Sensory Systems Reticular Formation Motor Systems Neurological Neuroanatomy Blood Supply to Brain Thalamic Nuclei and Connections Brainstem Histology Spinal Cord Cross-Sections Limbic System Limbic Lobe Limbic System: Noncortical Hippocampal Formation Amygdala Limbic Diencephalon Hypothalamus and Medial Forebrain Bundle Olfactory System Basal Forebrain Limbic Synthesis Catalog no. K19088, May 2015, c. 403 pp., Soft Cover, Pack - Book and Ebook, ISBN: 978-1-4665-8534-8 $69.95 / £44.99

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Royal Adelaide Hospital and University of Adelaide, Australia

The latest edition of this well-established, accessible introduction to neurophysiology succeeds in integrating the disciplines of neurology and neuroscience with an emphasis on principles and functional concepts.

In Neurophysiology: A Conceptual Approach, Fifth Edition, the authors deliver a refreshing alternative to “learning by rote,” employing a variety of techniques to encourage understanding. Readers can learn both the science underlying a particular phenomenon and what this means for individual body systems and for the body as a whole. The fifth edition retains the readable style of its predecessors—covering the entire subject of neurophysiology from the conduction of nerve impulses to the higher functions of the brain within a single accessible volume. A companion website offers free self-assessment material and access to the highly acclaimed NeuroLab resources Full of color explanatory diagrams, the book is an unrivalled "one-stop shop" for students of medicine, physiology and applied physiology, neurophysiology, neuroscience, and other bioscience courses looking for an integrated introduction to the challenging disciplines of neuroscience and neurology.

Contents: Neural Mechanisms The Study of the Brain Communication Within Neurons Communication Between Neurons Sensory Functions Skin Sense Proprioception Hearing Vision Smell And Taste Motor Functions Motor Control Systems Local Motor Control The Control of Posture Global Motor Control Higher Functions Associational Cortex and Memory Motivation and the Control of Behavior Catalog no. K16924, August 2012, 495 pp.

Pack - Book and Ebook, ISBN: 978-1-4441-3517-6 $54.95 / £34.99 Also available as an eBook

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Neuroanatomy / Neurophysiology Dopamine – Glutamate Interactions in the Basal Ganglia Edited by

Susan Jones University of Cambridge, UK

The basal ganglia are involved in complex brain functions, from voluntary movement control to learning and reward processing, and they are implicated in numerous neurological and psychiatric disorders. Information from the cerebral cortex and thalamus is conveyed to basal ganglia nuclei via glutamate release, while dopamine from the midbrain is released in close proximity to glutamate.

At the heart of both function and dysfunction of basal ganglia circuits is the interaction of these two neurotransmitters, dopamine and glutamate.

Elucidating the relationship between molecular and cellular effects and behavioural significance has been challenging, but in recent years, improved labeling, imaging, recording, and genetic manipulation approaches have yielded new information on how dopamine and glutamate interact to generate the circuit activity underpinning basal ganglia function.

Dopamine–Glutamate Interactions in the Basal Ganglia synthesizes this recent research from the level of receptor molecules all the way to complex behaviours and disease.

Current insights from research on individual neurons and synapses, detailed circuit analysis, and learning and action functions of the basal ganglia are presented against a historical perspective. The book also discusses compromised dopamine–glutamate interaction in disorders of basal ganglia function.

Atlas of the Neonatal Rat Brain Renuka Ramachandra and Thyagarajan Subramanian The Pennsylvania State University Hershey Medical Center, USA

Changes in the rat brain are rapid in the first two weeks after birth. Atlas of the Neonatal Rat Brain provides researchers in neurology, pharmacology, biology, and veterinary science with detailed color images of the normal developing rat brain. It presents photographic, histological illustrations of the anatomical features of the neonatal rat brain at postnatal (P)days P-1, P-7, and P-14.

Each plate is a photomicrograph composite that shows the entire brain in sagittal and coronal sections at each stage. The P-1 section contains 30 coronal plates and 14 sagittal plates and the P-7 section includes 27 coronal plates and 24 sagittal plates. The final P-14 section shows 41 coronal plates and 21 sagittal plates. Each set consists of contiguous sections from individual animals, and selections were based on the structural variability represented.

The sections are Nissl stained with Cresyl violet creating photomicrographs with high resolution and clarity. The structures are directly labeled on the images, making it easier to correlate data. Additional images are available as electronic resources for individuals who seek images not represented in this volume, and the electronic version allows labels to be removed so the atlas can be used as a teaching tool.

Contents:

Metabotropic Glutamate Receptor–Dopamine Interactions in the Basal Ganglia Motor Circuit Ionotropic Glutamate Receptors in the Basal Ganglia Dopamine Receptors and their Interactions with NMDA Receptors Synaptic Triad in the Neostriatum: Dopamine Glutamate and the MSN Dopaminergic Modulation of Glutamatergic Synaptic Plasticity in Striatal Circuits: New Insights from BAC-Transgenic Mice Striatal Acetylcholine–Dopamine Crosstalk and the Dorsal–Ventral Divide Electrophysiology of the Corticostriatal Network Functional Organization of the Midbrain Substantia Nigra ...

Introduction Nomenclature Histology Imaging P-1 Brain Coronal Plates (Figures 1 through 30) Sagittal Plates (Figures 31 through 44) P-7 Brain Coronal Plates (Figures 45 through 71) Sagittal Plates (Figures 72 through 95) P-14 Brain Coronal Plates (Figures 96 through 136) Sagittal Plates (Figures 137 through 157) Index

Catalog no. 88793, December 2011, 284 pp.

ISBN: 978-1-4200-8879-3, $159.95 / £106.00 Also available as an eBook

Catalog no. K11857, January 2011, 188 pp.

ISBN: 978-1-4398-4012-2, $179.95 / £112.00 Also available as an eBook

Contents:

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Neuroanatomy / Neurophysiology The Integrated Nervous System A Systematic Diagnostic Approach

The Third Histamine Receptor

University of Ottawa, Ontario, Canada

Selective Ligands as Potential Therapeutic Agents in CNS Disorders

Peter Humphreys

Edited by

Children's Hospital of Eastern Ontario, Ottawa, Canada

Divya Vohora

To demonstrate the connection between academic neuroanatomy and the practice of clinical neurology, this innovative textbook presents carefully chosen clinical cases that illustrate how the nervous system is constructed and how it functions under normal circumstances. Providing the foundation needed to encounter neurological diseases, it teaches readers how to integrate a patient’s clinical history and examination with neuroanatomy. In addition to color illustrations throughout, the book adds an invaluable DVD for further exploration and access to a state-ofthe-art website with additional materials that are updated periodically.

Since their discovery, the potential of histamine H3 receptor ligands in various CNS disorders has received much attention. This resource presents recent advances with an emphasis on pharmacology. It covers identification and localization of receptors and the development of novel ligands incorporating pre-clinical and clinical studies indicating earliest possible stages of development. The book provides an overview of histamine as a neurotransmitter and discusses receptor pharmacology, signal transduction, selective ligands, and therapeutic potential.

Walter Hendelman and Christopher R. Skinner

Catalog no. 45970, September 2009, 352 pp.

ISBN: 978-1-4200-4597-0, $96.95 / £61.99 Also available as an eBook

Hamdard University, New Delhi, India

Catalog no. 53922, November 2008, 400 pp.

ISBN: 978-1-4200-5392-0, $199.95 / £127.00 Also available as an eBook

Brain Aging

The Female Brain Second Edition

Models, Methods, and Mechanisms

Cynthia L. Darlington

Edited by

University of Otago, Dunedin, New Zealand

The first edition of this bestseller laid the groundwork for understanding the female brain, examining the evidence of structural and functional differences between the brains of males and females.

Addressing a wealth of current research, the second edition continues in this vein, leading readers through the basic principles of anatomy and physiology and on to the complex behavioral functions which constitute the workings of the normal and abnormal female brain. Filled with rigorous scientific analysis in an easily accessible format, the book delineates genderbased differences between brains and explains why they should be considered when designing research and clinical studies.

Catalog no. 77449, April 2009, 266 pp.

ISBN: 978-1-4200-7744-5, $154.95 / £99.00 Also available as an eBook

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David R. Riddle Wake Forest University, Winston-Salem, North Carolina, USA

Bringing together critical studies of brain aging in animal models and insights from human brain imaging, this text focuses on fundamental age-related changes in the brain. Offering significant depth and breadth of coverage, it provides an overview of structural and functional changes at the molecular, systems, and cognitive levels. Written by pioneering researchers, it reviews unbiased methods for quantifying changes and stereological methods for clarifying the extent and nature of age-related neurological changes. It also explores the distinct methodological challenges inherent in investigating the aging nervous system.

Catalog no. 3818, April 2007, 408 pp.

ISBN: 978-0-8493-3818-2, $169.95 / £121.00 Also available as an eBook

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Neuroscience & Health Coming Soon!

New!

Restoring the Brain

Melatonin

Neurofeedback Training and Optimizing Brain Health and Function Edited by

Hanno W. Kirk Lewisburg, West Virginia, USA

Restoring the Brain: Neurofeedback Training and Optimizing Brain Health and Function describes the history and process by which neurofeedback has become an effective tool for treating many mental and behavioral health conditions. It explains how new brain research and improvements in imaging technology (fMRI, SPECT) allow for the reconceptualization of the brain and describes how practitioners can integrate neurofeedback into their medical practice. It also discusses how biomedical factors can degrade brain functioning and cause a wide range of mental health symptoms. The book shares the clinical experience of practitioners working with specific symptom constellations which would generally be categorized by a DSM diagnostic label.

Features: • Brings together experts and experienced practitioners who explain in accessible language the new findings on brain functioning • Describes how viewing the brain as a complex electrical system has led to efforts to influence brain functioning through the practice of neurofeedback • Describes the use of neurofeedback as a non-invasive, non-pharmacological supplement to traditional medical or mental health treatment • Includes stories by clinicians of their work and successes with neurofeedback • Provides easy-to-understand explanations of how and why neurofeedback works

Selected Contents: History of Neurofeedback Paradigms for understanding Brain Functioning: Neurochemical to Neuroelectrical The Role of Astrocytes in Brain Functioning The evolution of Clinical Neurofeedback Practice Neurofeedback in an Integrative Medical Practice Biomedical Factors That Impact Brain Function Neurofeedback for PTSD Symptom Reduction Implementing Neurofeedback at Forward Operating Base Combat Stress Clinic in Afghanistan Neurofeedback in the Treatment of Attention Deficit Disorder and other Learning disabilities ...

Catalog no. K24152, April 2015, c. 288 pp.

ISBN: 978-1-4822-5877-6, $129.95 / £82.00 Also available as an eBook

Therapeutic Value and Neuroprotection Edited by

Venkatramanujan Srinivasan, Gabriella Gobbi, Samuel D. Shillcutt, and Sibel Suzen There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases and other ailments. Topics include: • The basic aspects of melatonin’s physiology, including its production, bioavailability, and metabolism • The functional importance of melatonin receptors and their role in mediating the therapeutic effectiveness of melatonin in cancer • Melatonin’s effect on the regulation of blood pressure, sleep, and circadian rhythms • The cardioprotective role of melatonin • The neuroprotective role in glaucoma, Alzheimer’s disease, Parkinson’s disease, and neurodegenerative diseases • Use as a therapeutic agent for treating epilepsy and degenerative discs • Treatment for obesity, diabetes mellitus, and other metabolic disorders • Protective role in peri-natal hypoxic-ischemia

Selected Contents : Melatonin Production and Bioavailability Therapeutic Applications of Melatonin in Pediatrics Melatonin’s Cardioprotective Role Melatonin: Therapeutic Value and Neuroprotection in Stroke Melatonin’s Antiapoptotic Activity in Neurodegenerative Diseases Melatonin’s Neuroprotective Role in Parkinson’s Disease Neuroprotective Role of Melatonin in Glaucoma Melatonin Receptors and Their Preventive Role in Carcinogenesis Melatonergic Drugs as Therapeutic Agents for Insomnia and Depressive Disorders Effects of Melatonin and Melatonergic Drugs in Transgenic Mouse Models of Alzheimer’s Disease ...

Catalog no. K22184, October 2014, 573 pp.

ISBN: 978-1-4822-2009-4, $199.95 / £127.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neuroscience & Health Diet, Brain, Behavior

Viral Hemorrhagic Fevers Edited by

Practical Implications

Sunit K. Singh

Edited by

Robin B. Kanarek

Banaras Hindu University (BHU), Varanasi, India

Daniel Ruzek

Tufts University, Medford, Massachusetts, USA

Biology Centre ASCR- Institute of Parasitology, Ceske Budejovice, Czech Republic

Harris R. Lieberman USARIEM, Natick, Massachusetts, USA

Viral hemorrhagic fevers have captured the imagination of the public and made their way into popular books and movies by virtue of their extreme virulence and mysterious origins. Since 2001, concerns have grown about the potential use of many hemorrhagic fever viruses as biological weapons. This has led to a resurgence in research to develop improved diagnostics, vaccines, and therapeutics—both for biodefense purposes and to treat naturally exposed persons.

Written by international experts, Viral Hemorrhagic Fevers represents a major contribution to the virological literature and updates the state of knowledge of these dangerous illnesses.

As the field of nutritional neuroscience has grown, both the scientific community and the general population have expressed a heightened interest in the effect of nutrients on behavior. Diet, Brain, Behavior: Practical Implications presents the work of a diverse group of scientists who collectively explore the broad scope of research in the field.

Selected Contents: General Aspects General Disease Pathology in Filoviral and Arenaviral Infections Interaction of the Host Immune System with Hemorrhagic Fever Viruses Vascular Endothelium and Hemorrhagic Fever Viruses Vascular Endothelial Dysfunctions: Viral Attack and Immunological Defense Animal Models of Viral Hemorrhagic Fevers Role of Rodents and Bats in Human Viral Hemorrhagic Fevers BSL4 Workforce Preparedness in Hemorrhagic Fever Outbreaks Major Strategies for Prevention and Control of the Viral Hemorrhagic Fevers ...

Specific Infections Pathogenic Old World Arenaviruses Lassa Fever Lujo Virus Hemorrhagic Fever Argentine Hemorrhagic Fever Bolivian Hemorrhagic Fever "Venezuelan" Hemorrhagic Fever Rift Valley Fever Virus and Hemorrhagic Fever Crimean–Congo Hemorrhagic Fever Virus Hemorrhagic Fever with Renal Syndrome Infection Marburg Virus Disease Dengue Hemorrhagic Fever Yellow Fever Virus Infection Kyasanur Forest Disease ...

Index Catalog no. K13962, July 2013, 596 pp.

ISBN: 978-1-4398-8429-4, $149.95 / £95.00 Also available as an eBook

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Topics discussed include: • Concepts of mental energy and fatigue • The dangers of obesity and its effect on behavior • Exercise, dietary restriction, and supplements for weight loss • The effects of caffeine, creatine, theanine, B vitamins, and other dietary supplements on brain functioning and behavior • The reward deficiency hypothesis and eating disorders • The importance of maintaining proper fluid intake • The effects of eating breakfast on performance • The role of diet in pain sensitivity

Selected Contents: Mental Energy and Fatigue: Science and the Consumer Hydration and Brain Function Diet as an Analgesic Modality Breakfast and Adult and Child Behaviors Diet, Physical Activity, and Substrate Oxidation: Implications for Appetite Control, Weight Loss, and Body Composition The Reward Deficiency Hypothesis: Implications for Obesity and Other Eating Disorders Potential Consequences of Obesity on Cognitive Behavior Dietary Supplements for Weight Loss Sweet Taste Preferences and Cravings in Gestational Diabetes Mellitus (GDM): Implications for Diet and Medical Management Homocysteine, B Vitamins, and Cognitive Function Caffeine Effects on Aggression and Risky Decision Making Index Catalog no. K11143, October 2011, 335 pp.

ISBN: 978-1-4398-2156-5, $149.95 / £95.00 Also available as an eBook

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KMN05_5.5x8.5_MC_Temp 10/2/14 10:37 AM Page 15

Neurobiology Neurobiology of Chemical Communication

The Neurobiological Basis of Suicide

Edited by

Edited by

Carla Mucignat-Caretta

Yogesh Dwivedi

University of Padova, Italy

University of Illinois at Chicago, USA

In the last two decades, scientists have developed a greater understanding of the neural processing of intraspecific chemical signals known as pheromones.

Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans.

The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones.

An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding the pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also present a promising approach to developing more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology.

Selected Contents: Pheromones and General Odor Perception in Insects First Investigation of the Semiochemistry of South African Dung Beetle Species Pheromone Reception in Insects: The Example of Silk Moths Chemical Communication in the Honey Bee Society Drosophila Pheromones: From Reception to Perception How Drosophila Detect Volatile Pheromones: Signaling, Circuits, and Behavior Chemical Signaling in Amphibians Vomeronasal Receptors and Signal Transduction in the Vomeronasal Organ of Mammals Central Processing of Intraspecific Chemical Signals in Mice Social Cues, Adult Neurogenesis, and Reproductive Behavior Pheromone of Tiger and Other Big Cats Cattle Pheromones Pheromones for Newborns Pheromone Processing in Relation to Sex and Sexual Orientation Human Pheromones: Do They Exist?

Index Catalog no. K15274, February 2014, 612 pp.

ISBN: 978-1-4665-5341-5, $149.95 / £95.00 Also available as an eBook

Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they are often weak predictors and can be of less clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior.

The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. This volume focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Selected Contents: Diagnosis, Traits, States, and Comorbidity in Suicide Neuroanatomy of Serotonergic Abnormalities in Suicide Noradrenergic Dysfunction in Depression and Suicide Role of the Endocannabinoid System in the Neurobiology of Suicide Stress–Diathesis Model of Suicidal Behavior Brain-Derived Neurotrophic Factor in Suicide Pathophysiology Neuroimaging: High Risk States for Suicide Gene–Environment Interaction and Suicidal Behavior Genetic Factors and Suicidal Behavior Epigenetic Effects of Childhood Adversity in the Brain and Suicide Risk Genetics of Suicidal Behavior in Children and Adolescents Neurobiology of Teenage Suicide Suicide in Late Life Intermediate Phenotypes in Suicidal Behavior: Focus on Personality ...

Catalog no. K11764, June 2012, 482 pp.

ISBN: 978-1-4398-3881-5, $149.95 / £95.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neurobiology Astrocytes

Neurobiology of Depression

Wiring the Brain Edited by

Edited by

Eliana Scemes and David C. Spray

Francisco Lopez-Munoz

Albert Einstein College of Medicine, Bronx, New York, USA

Astrocytes play diverse roles in central nervous system (CNS) function and dysfunction, and the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural tasks. Bringing together contributions from international experts at the top of their field, Astrocytes: Wiring the Brain emphasizes cellular connections and surveys the most current findings on astrocyte activity.

The first section identifies major astrocyte biomarkers and describes how they define the different connectivity domains. Next, the book examines the role of these connections. It explains how their function can be manipulated under physiological conditions and how dysfunction of the connectivity leads to aberrant brain performance. The final section explores the alterations of glia that have been observed in specific diseases of the brain. These include epilepsy, autoimmune encephalitis, Alzheimer’s disease, autism, and major depression. The book identifies key mechanisms responsible for these alterations.

Contents: Introduction to Cluster A: Functional Biomarkers at the Interface Mature Protoplasmic Mammalian Astrocytes: Morphology, Interrelationships, and Implications for Function Biomarkers of Astrocyte Microdomains: Focus on Gap Junctions, Purinergic Receptors, and Aquaporins Adhesion Molecules and their Function in Astrocyte Polarity ...

Introduction to Cluster B: Establishment of Functional Units: Multimodality at the Tips Neuroglial Networks: Glial Wiring Also Matters Astrocyte-Neuron Communication: What Goes Wrong in Pathology? Blood-Brain Barrier and the Neural Vascular Unit Oligodendrocytes: Gateway to the Panglial Syncytium Microglia and Non-CNS Cells in Paracrine Signaling and CNS Immunity: Effects of Pathogens, Age, and Life History CNS Pathology: Disruption of Astrocyte Connectivity: Introduction Astrocytes in Epilepsy Astrocyte Involvement in the Acquired Demyelinating The Role of Glial Pathology in Autism ...

Index Catalog no. K11240, November 2011, 440 pp.

ISBN: 978-1-4398-2584-6, $159.95 / £106.00 Also available as an eBook

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University of Alcalá, Madrid, Spain and Camilo José Cela University, Madrid, Spain

Cecilio Alamo University of Alcalá, Madrid, Spain

With the collaboration of the most prestigious international specialists in biochemistry, molecular biology, genomics, psychiatry, psychology, and pharmacology, Neurobiology of Depression discusses the nature of the central nervous system circuits responsible for the modifications of neuronal functioning that lead to depression.

The book begins by discussing models of depression, neural foundations, and genetic factors before moving to a discussion of role of psychopharmacology in treatment. It also examines the effect of biological rhythms on the human body.

Later chapters review the role of CRF-related ligands, CRF receptors, HPA axis activity, and glucocorticoid receptors in the regulation of the stress response and depression.

Exploring myriad aspects of a disease that plagues a large percentage of the population worldwide, this volume captures the state of the science of this debilitating disorder, facilitating further research and discovery.

Selected Contents: Animal Models of Depression Neurophysiological and Neuropsychological Models of Depression Neural Foundations of Major Depression: Classical Approaches and New Frontiers Genetic Regulation of Emotion Brain Circuitries Development of Brain Monoaminergic Systems Serotonergic Pathways in Depression Noradrenergic System in Depression Glutamatergic System and Mood Disorders Role of the Endocannabinoid System in Etiopathology of Major Depression Opioid System and Depression Chronobiological Rhythms, Melatonergic System, and Depression Depression and Cytokine-Regulated Pathways Role of Neuropeptide Y in Depression: Current Status Nitric Oxide Signaling in Depression and Antidepressant Action Brain-Derived Neurotrophic Factor and Major Depression ...

Catalog no. K11746, September 2011, 522 pp.

ISBN: 978-1-4398-3849-5, $159.95 / £106.00 Also available as an eBook

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KMN05_5.5x8.5_MC_Temp 10/2/14 10:37 AM Page 17

Neurobiology Neurobiology of Sensation and Reward Edited by

Jay A. Gottfried

Neurobiology of Huntington’s Disease Applications to Drug Discovery

Northwestern University, Chicago, Illinois, USA

Edited by

Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain.

Duke University Medical Center, Durham, North Carolina, USA

Emphasizing the role of reward in reinforcing behaviors, the book begins with an exploration of the history, ecology, and evolution of sensation and reward.

Progressing through the five senses, contributors explore how the brain extracts information from sensory cues. The authors examine how different animal species predict rewards, thereby integrating sensation and reward in learning, focusing on effects in anatomy, physiology, and behavior.

Contents: First Principles Introduction: From Traditional Fixed Cortical Sensationism to Contemporary Plasticity of Primary Sensory Cortical Representations A Brief History of Sensation and Reward Reward: What Is It? How Can It Be Inferred from Behavior?

What Can Different Brains Do with Reward?

A Systems Organization of the Senses Smell Taste Touch Sight Sound Sensory Agnosias From Sensation to Reward Neuroanatomy of Reward: A View from the Ventral Striatum Multiple Reward Layers in Food Reinforcement Sensation, Incentive Learning, and the Motivational Control of Goal-directed Action Reward Predictions and Computations Orbitofrontal Cortex and Outcome Expectancies: Optimizing Behavior and Sensory Perception The Neurology of Value Civilized Sensory Rewards (Distinctly Human Rewards): Perfume Visual Art Music Index Catalog no. 67265, March 2011, 466 pp.

ISBN: 978-1-4200-6726-2, $159.95 / £106.00 Also available as an eBook

Donald C. Lo Robert E. Hughes Buck Institute for Age Research, Novato, California, USA

Highlighting advances in the discovery and development of new drug therapies for neurodegenerative disorders, this volume focuses on the many aspects of the research on drugs to treat Huntington's disease. It discusses genetics, genomics, and proteomics, and the latest in high-throughput and high-content screening. The authors provide introductory background as well as highly sophisticated information on current and future directions of research. Exploring the interplay between academic and industrial research, the investment community, and non-profit contributors, the book also examines the practical realities of preclinical testing, clinical testing strategies, and, ultimately, clinical usage.

Catalog no. 9000, July 2010, 338 pp.

ISBN: 978-0-8493-9000-5, $169.95 / £112.00 Also available as an eBook

The Neurobiology of Olfaction Edited by

Anna Menini S.I.S.S.A, Trieste, Italy

A comprehensive overview of the current status of knowledge and research on olfaction, this volume takes an interdisciplinary approach to include content from genetics to behavior and from nematodes to humans.

It presents the most recent discoveries in odor coding from the olfactory epithelium to the cortical centers, and in neurogenesis in the olfactory epithelium and the olfactory bulb. Edited by a top researcher in the field, each subject-specific chapter provides an extensive list of reviews and original articles for students and scientists interested in further reading.

Catalog no. 71971, November 2009, 448 pp.

ISBN: 978-1-4200-7197-9, $169.95 / £124.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neurobiology Biology of the NMDA Receptor Edited by

Antonius M. VanDongen

Edited by

Duke University Medical Center, Durham, North Carolina, USA

The NMDA receptor, a subclass of the ionotropic glutamate receptor family, plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied.

This text describes all important aspects of NMDA receptor biology, highlighting exciting new discoveries that have been made over the past decade. It provides a comprehensive review of various molecular genetics studies that illustrate the importance of this class of receptors. The book also discusses recent crystallographic x-ray structures of its ligand binding domains.

Catalog no. 44141, October 2008, 350 pp.

ISBN: 978-1-4200-4414-0, $169.95 / £121.00 Also available as an eBook

Manual of Stroke Models in Rats Edited by

Yanlin Wang-Fischer Palatin Technologies, Cranbury, New Jersey, USA

While new insights into the mechanisms and the treatment of stroke have been obtained from animal experiments over the past several years, this is the first book in more than two decades to compile research in this essential area.

With contributions from a group of cutting-edge researchers, it offers detailed explanations of the methods and techniques for accomplishing different stroke models in rats. The book provides a starting point for those researchers employing stroke models to develop new drugs to counteract this problem.

Catalog no. 9578, August 2008, 352 pp., Soft Cover ISBN: 978-0-8493-9578-9, $125.95 / £82.00 Also available as an eBook

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Serotonin Receptors in Neurobiology Amitabha Chattopadhyay Center for Cellular & Molecular Biology, Hyderabad, India

Modulating mood, appetite, sexual activity, body temperature, and sleep, serotonin has implications in numerous disease states, including depression, anxiety, social phobia, schizophrenia, obsessive-compulsive disorder, and panic disorder. Approaching the subject from a multidisciplinary perspective, this text is among the first to be published in the wake of serotonin receptor knock-out studies. With contributions from leading experts in their fields, this book covers a range of topics from contemporary techniques in receptor research to fundamental interactions of the 5-HT receptors with the lipid bilayer to behavioral studies.

Catalog no. 3977, May 2007, 224 pp.

ISBN: 978-0-8493-3977-6, $169.95 / £117.00 Also available as an eBook

Neural Plasticity and Memory From Genes to Brain Imaging Edited by

Federico BermudezRattoni National University of Mexico, Mexico City, Distrito Federal

This volume provides a multidisciplinary review of research being conducted on the neurobiology of memory. It examines the synaptic communication elements identified as being susceptible to modification through the accumulation of experience. It also explains how cell circuitry is modulated and ultimately modified by neurotransmitters and hormones during the process of acquiring, consolidating, and retrieving information. In each chapter, researchers present findings and explain their innovative methodologies. The text also addresses current memory studies involving human brain imaging.

Catalog no. 9070, April 2007, 368 pp.

ISBN: 978-0-8493-9070-8, $169.95 / £121.00 Also available as an eBook

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KMN05_5.5x8.5_MC_Temp 10/2/14 10:37 AM Page 19

Developmental Biology Atlas of Human Central Nervous System Development (Five-Volume Set) Shirley A. Bayer and Joseph Altman Indianapolis, Indiana, USA

From the 1960s through the 1980s, the work of legendary pioneers Shirley Bayer and Joseph Altman chronicled the development of the rat nervous system. In the 1990s, they shifted their attention to humans when they realized how little was known about the development of the human central nervous system. Many disorders resulting from abnormal neural deficits could be better understood if normal development was itself better known.

The award-winning Atlas of Human Central Nervous System Development provides a complete record of the development of the human central nervous system from spinal cord gestation through the third trimester. Divided into five volumes, the contents of the atlases are organized by coronal, sagittal, and horizontal planes of sectioning to ensure that nearly every structure in the developing brain is represented pictorially.

Each volume provides two-page spreads containing high-resolution black and white images on one side and ghost images on the other with unabbreviated labels to apprise readers of the exact structures identified. The final volume provides a concluding essay that summarizes major events of CNS development, while offering a theoretical account of the morphogenetic processes involved.

Contents: Vol. 1: The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month Vol. 2: The Human Brain During the Second Trimester Vol. 3: The Human Brain During the Third Trimester Vol. 4: The Human Brain During the Late First Trimester Vol. 5: The Human Brain During the Early First Trimester Catalog no. 68008, July 2007, 2160 pp.

ISBN: 978-1-4200-6800-9, $938.00 / £596.00

The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month Catalog no. 1420 May 2002, 256 pp.

ISBN: 978-0-8493-1420-9 $273.00 / £174.00 Also available as an eBook

The Human Brain During the Third Trimester Catalog no. 1421, December 2003, 392 pp.

ISBN: 978-0-8493-1421-6, $252.00 / £161.00 Also available as an eBook

The Human Brain During the Second Trimester Catalog no. 1422 May 2005, 384 pp.

ISBN: 978-0-8493-1422-3, $231.00 / £147.00 Also available as an eBook

The Human Brain During the Late First Trimester Catalog no. 1423 April 2006, 592 pp.

ISBN: 978-0-8493-1423-0 $241.00 / £153.00 Also available as an eBook

The Human Brain During the Early First Trimester Catalog no. 1424 July 2007, 536 pp.

ISBN: 978-0-8493-1424-7 $220.00 / £141.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neurotechnology Coming Soon!

New!

The Textbook of Advanced Neurophotonics and Brain Mapping

Neurotechnology in National Security and Defense

Yu Chen

Practical Considerations, Neuroethical Concerns

University of Maryland, College Park, USA

Edited by

Babak Kateb

James Giordano Georgetown University, Washington, D.C., USA and Potomac Institute for Policy Studies, Arlington, Virginia, USA

Edited by

Cedars Sinai Medical Center, West Hollywood, California, USA

Understanding how the brain works and developing effective therapeutics are important in advancing neuroscience and improving clinical patient care. The Textbook of Advanced Neurophotonics and Brain Mapping covers state-of-the-art research and development in optical technologies and applications for brain mapping and therapeutics.

The book covers optical methods for imaging, sensing, and manipulating brain structure and function, as well as multiphoton microscopy, functional brain mapping, image-guided neurosurgery, and optogenetics. Structured around literature-based studies, it focuses on disease diagnostics and therapeutics in addition to current methodologies. The book also discusses optical imaging in the context of neurosciences. It reviews recent developments in minimally invasive endoscopic imaging of deep brain structure and function, as well as light-based therapy.

Selected Contents: Clinical Translation of Optical Imaging and Spectroscopy Opportunities and Challenges of Near-Infrared Spectroscopy (NIRS) to Study Cognitive Functions Shedding Near-Infrared Light on Brain Networks Monitoring Pain Using Functional Near-Infrared Spectroscopy (fNIRS) ...

Optical Imaging of Brain Function: From Animal to Human Optical imaging of Brain Functional Changes in Cocaine Mice In Vivo Brain Optical Imaging for the Study of Normal Brain Function and Disease ...

Emerging Technologies for Neuroimaging Novel Scattering Anisotropy Based Method for Tractography: A New Atlas of The Brain Neurovascular Photoacoustic Microscopy Light-based Intervention Guidance and Therapy Intra-operative Optical Guidance for Neurosurgery Laser Stimulation of Nerves ...

Catalog no. K23139, September 2015, c. 488 pp.

ISBN: 978-1-4822-3685-9, $139.95 / £89.00 Also available as an eBook

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Neurotechnology in National Security and Defense: Practical Considerations, Neuroethical Concerns is the second volume in the Advances in Neurotechnology series. It specifically addresses the neuroethical, legal, and social issues arising from the use of neurotechnology in national security and defense agendas and applications. Of particular concern are the use of various neurotechnologies in military and intelligence operations training, acquisition of neurobiological and cognitive data for intelligence and security, military medical operations, warfighter performance augmentation, and weaponization of neuroscience and neurotechnology. The contributors discuss the neuroethical questions and problems that these applications generate as well as potential solutions that may be required and developed.

The book examines how developments in neurotechnology in national security and defense agendas are impacted by and affect ethical values and constructs, legal considerations, and overall conduct of the social sphere. Presenting an integrative perspective, leading international experts lay the scientific groundwork and establish the premises necessary to appreciate the ethical aspects of neurotechnology in national security and defense.

Selected Contents: Transitioning Brain Research: From Bench to Battlefield Neural Systems in Intelligence and Training Applications Neurocognitive Engineering for Systems’ Development Neural Mechanisms as Putative Targets for Warfighter Resilience and Optimal Performance Neurotechnology and Operational Medicine "NEURINT" and Neuroweapons: Neurotechnologies in National Intelligence and Defense Brain Brinksmanship: Devising Neuroweapons Looking at Battlespace, Doctrine, and Strategy Neuroscience, National Security, and the Reverse Dual-Use Dilemma Neuroskepticism: Rethinking the Ethics of Neuroscience and National Security ...

Catalog no. K22583, September 2014, 315 pp.

ISBN: 978-1-4822-2833-5, $99.95 / £63.99 Also available as an eBook

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KMN05_5.5x8.5_MC_Temp 10/2/14 10:37 AM Page 21

Neurotechnology The Textbook of Nanoneuroscience and Nanoneurosurgery Edited by

Babak Kateb Cedars Sinai Medical Center, West Hollywood, California, USA

John D. Heiss National Institutes of Health, Bethesda, Maryland, USA

Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the potential to revolutionize medicine and improve the prevention, diagnosis, and treatment of neurological disorders over the next 1020 years. The Textbook of Nanoneuroscience and Nanoneurosurgery presents a state-of-the-art review of the field, providing current information about nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology.

The book describes advances that have already been translated to the clinic or hold significant promise for future application in nanoneurosurgery, as well as their potential impact. A full-color text, the book contains contributions by more than 120 researchers, original and descriptive illustrations, and more than 3,000 references. Offering broad coverage of nanotechnological applications in diverse areas and addressing FDA regulation and healthcare policy, this volume provides a foundation of ideas and methods for scientists and physicians to devise successful, less invasive procedures for future treatment of nervous system disorders.

Selected Contents:

Neurotechnology Premises, Potential, and Problems Edited by

James Giordano Georgetown University, Washington, D.C., USA and Potomac Institute for Policy Studies, Arlington, Virginia, USA

New technologies that allow us to investigate mechanisms and functions of the brain have shown considerable promise in treating brain disease and injury. These emerging technologies also provide a means to assess and manipulate human consciousness, cognitions, emotions, and behaviors, bringing with them the potential to transform society. Neurotechnology: Premises, Potential, and Problems explores the technical, moral, legal, and sociopolitical issues that arise in and from today’s applications of neuroscience and technology and discusses their implications for the future.

Topics include: • The potential and limitations of neuroimaging technology in determining patient prognoses • Neuroprostheses: restoration of functions of the disabled vs. enhancement to transhuman capabilities • Deep brain stimulation and its use in restoring, preserving, or changing patients’ personal identity • Cyborg technology and its potential to change our vision of humanity • Methodologies for reducing the risk of neurotechnology’s impact on ethical, legal, and social issues

Nanoneurology and Nanoneurosurgery Peptide and Protein-Based Nanoparticles Dendrimers Immune-Based Targeting in Cancer Transport of Nanoparticles across Blood–Brain Barrier Focused Ultrasound for Noninvasive Neuromodulation Nanosensors Implantable Infusion Pumps Incorporating Nanotechnology Therapy for Neuronopathic Lysosomal Storage Diseases Nanotechnology for Cerebral Aneurysm Treatment Improving Treatment of Stroke through Nanotechnology Molecular Medical Devices for Nanoneurosurgery Applications of Nanotechnology in Epilepsy Applications of Nanotechnology to Diseases of the Spine

Selected Contents:

Catalog no. K12237, July 2013, 602 pp.

ISBN: 978-1-4398-4941-5, $299.95 / £191.00 Also available as an eBook

Catalog no. K11241, April 2012, 354 pp.

ISBN: 978-1-4398-2586-0, $119.95 / £77.00 Also available as an eBook

Neurotechnology as Demiurgical Force: Avoiding Icarus’ Folly Is the Use of Neurotechnology in Education an Enablement, Treatment, or Enhancement?

Images of Uncertainty: Two Cases Neuroprostheses: Implications of the Current and Future State of the Science and Technology Promises and Perils of Cognitive Performance Tools: A Dialogue The Age of Neuroelectronics Ethical Issues in Performance-Enhancing Technologies: From Bench to Headline The Cyborg and Cyborgization Is Neuroenhancement Unnatural, and Does It Morally Matter?

A Surety Engineering Framework and Process to Address Ethical, Legal, and Social Issues for Neurotechnologies ...

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Neurotechnology Neuroproteomics Edited by

Oscar Alzate University of North Carolina, Chapel Hill, USA

With an extensive background in mathematics and physics, editor Dr. Oscar Alzate exemplifies the newest generation of biological systems researchers. In this volume, he organizes an overview of neuroproteomics that is practical and progressive.

Approaches discussed include mass spectrometry, electrophoresis, chromatography, surface plasmon resonance, protein arrays, immunoblotting, computational proteomics, and molecular imaging. Leading researchers detail the principles, approaches, and difficulties of the techniques, showcasing the questions that neuroproteomics can answer as well as those it raises. The book includes research that is redefining our understanding of Parkinson’s, Alzheimer’s and other neurological and mental diseases.

Catalog no. 76256, October 2009, 354 pp.

ISBN: 978-1-4200-7625-7, $169.95 / £124.00 Also available as an eBook

In Vivo Optical Imaging of Brain Function

Indwelling Neural Implants Strategies for Contending with the In Vivo Environment Edited by

William M. Reichert Duke University, Durham, North Carolina, USA

This compendium of contributions from noted experts in neuroprosthetics and tissue repair addresses the impact, characterization, and mitigation of the healing of tissues that surround an implant. It examines performance issues of implanted neuroprosthetics, presents both in vitro and in vivo approaches to assessing wound healing response to materials, and describes molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between electrode and surrounding tissue.

Catalog no. 9362, December 2007, 296 pp.

ISBN: 978-0-8493-9362-4, $189.95 / £121.00 Also available as an eBook

Second Edition

Methods for Neural Ensemble Recordings

Edited by

Second Edition

Ron D. Frostig University of California, Irvine, California, USA

Reflecting continual development in this emerging area, this volume reaches across disciplines to review a variety of noninvasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as optical hardware, cognitive behavior, and neuroscience present a host of perspectives that range from a single neuron to large assemblies of neurons several million strong, captured at various temporal and spatial resolutions. Introducing techniques that were unavailable just a few years ago, the book describes their theory, setup, and analytical methods and provides examples that highlight the advantages of each particular method.

Catalog no. 76841, May 2009, 428 pp.

ISBN: 978-1-4200-7684-4, $169.95 / £112.00 Also available as an eBook

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Edited by

Miguel A. L. Nicolelis Duke University Medical Center, Durham, North Carolina, USA

This second edition of a bestseller distills the current state of the science and provides the nuts and bolts foundation of the methods involved in this rapidly growing science. With contributions from pioneering researchers, it discusses microwire array design for chronic neural recordings, new surgical techniques for chronic implantation, microelectrode microstimulation of brain tissue, multielectrode recordings in the somatosensory system, and recordings from the central gustatory-reward pathways. It also explores the use of Brain-Machine Interface to restore neurological function and proposes conceptual and technical approaches to human neural ensemble recordings in the future.

Catalog no. 7046, December 2007, 296 pp.

ISBN: 978-0-8493-7046-5, $189.95 / £121.00 Also available as an eBook

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KMN05_5.5x8.5_MC_Temp 10/2/14 10:37 AM Page 23

Neuropsychology / Neuropsychiatry Coming Soon!

Translational Research in Traumatic Brain Injury Edited by

Daniel Laskowitz and Gerald Grant Duke University, Durham, North Carolina, USA

Translational Research in Traumatic Brain Injury is designed to address the key issues in the epidemiology, basic science, and treatment of traumatic brain injury (TBI). Edited by two clinically active physician scientists, the book presents contributions from faculty who are international leaders in the areas of molecular biology, translational modeling, treatment, and rehabilitation of traumatic brain injury.

The book covers a wide scope of TBI research critically important to the neurobiology research community, clinicians involved in the care of TBI patients, as well as industry leaders interested in developing new therapies for acute brain injury. It examines the full spectrum of TBI events, from mild sports-related injuries to severe blast injuries. It discusses fundamental cell mechanisms and pathophysiology, as well as animal modeling, clinical diagnosis, current therapeutic strategies, and future treatments. The book also describes long-term neuropsychiatric symptoms and the relationship of TBI to the development of postconcussive syndrome and post-traumatic stress disorder.

Contents:

New!

Psychodynamic Neurology Dreams, Consciousness, and Virtual Realty Allan Hobson Harvard Medical School, Boston, Massachusetts, USA

Psychodynamic Neurology: Dreams, Consciousness, and Virtual Realty presents a novel way of thinking about the value of dreaming.

Grounded in scientific research, the book also presents perspectives on psychoanalytic interpretation and other forms of dream analysis.

This book: • Surveys the remarkable history of sleep research over the past few decades • Examines the neurobiology of sleep and its implications for consciousness and well-being • Addresses the nature of waking and dreaming consciousness and how they are deeply related • Presents the neurogenesis, function, and clinical importance of a brain-based dream theory Our dreams are a mixture of anticipated virtual as well as remembered real experience. This book tells the story of how neuroscience has helped us reach this startling and exciting conclusion and how the new scientific model builds upon and departs from the dream theories of the past.

Epidemiology Epidemiology Sports Injury Pathophysiology Diffuse Axonal Injury BBB Breakdown Cellular Neuroplasticity after TBI Neuroinflammation Neurosteroids ...

Diagnosis of TBI Biomarkers Radiology Current Treatment and Sequelae Current Therapeutic Strategies Epilepsy after TBI Neurocognitive Sequelae and Relationship to PTSD ...

Clinical Trials and Future Therapies Clinical Trials in TBI Clinical Trials in PTSD Cell-based Therapies in TBI ...

Contents:

Catalog no. K19065, May 2015, c. 368 pp.

ISBN: 978-1-4665-8491-4, $149.95 / £95.00 Also available as an eBook

Catalog no. K24246, October 2014, c. 282 pp.

Soft Cover, ISBN: 978-1-4822-6054-0 $39.95 / £25.99

Historical Background: The Brain-Mind Schism of 1900 Neurological Development: Sleep and Dream Science Lucid Dreaming: Splitting Primary and Secondary Consciousness Heat and Light: Energy and Information Management Religion and Sexuality: Civil War in the Brain-Mind The Psychodynamic Ego: An Epigenetic Self The Transcendental Ego: Art and the Science of the Brain-Mind Instinct and Emotion: The Ethology of the Brain-Mind Psychopathology: Dysfunctions of the Brain-Mind Memory: Epigenetics and Experience Altered States: Toward a Science of the Brain-Mind Brain-Mind Dream Interpretation: A New Project for a Scientific Psychology

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Neuropsychology / Neuropsychiatry The Neural Bases of Multisensory Processes

Concussive Brain Trauma Neurobehavioral Impairment & Maladaptation, Second Edition

Edited by

Micah M. Murray CIBM, Lausanne, Switzerland

Rolland S. Parker

Mark T. Wallace

New York University School of Medicine, USA

Vanderbilt Brain Institute, Nashville, Tennessee, USA

It has become accepted in the neuroscience community that perception and performance are quintessentially multisensory by nature. Using the full palette of modern brain imaging and neuroscience methods, The Neural Bases of Multisensory Processes details current understanding in the neural bases for these phenomena as studied across species, stages of development, and clinical statuses.

The book begins by discussing anatomy—essential for understanding the neural substrates of multisensory processing. It describes neurophysiological bases and explains how multisensory stimuli can dramatically change the encoding processes for sensory information. Next, it reviews combinatorial principles and modeling, focusing on efforts to gain a better mechanistic handle on multisensory operations and their network dynamics. It explores clinical manifestations and explains how perception and action are affected by altered sensory experience. Other topics include development and plasticity, as well as attention and spatial representations.

The last sections of the book focus on naturalistic multisensory processes in three separate contexts: motion signals, multisensory contributions to the perception and generation of communication signals, and how the perception of flavor is generated. The text provides a solid introduction for newcomers and a strong overview of the current state of the field for experts.

Contents: Anatomy Neurophysiological Bases Combinatorial Principles and Modeling Development and Plasticity Clinical Manifestations Attention and Spatial Representations Naturalistic Multisensory Processes: Motion Signals Naturalistic Multisensory Processes: Communication Signals Naturalistic Multisensory Processes: Flavor Index Catalog no. K10614, August 2011, 809 pp.

ISBN: 978-1-4398-1217-4, $159.95 / £106.00 Also available as an eBook

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This second edition of the bestselling Concussive Brain Trauma: Neurobehavioral Impairment & Maladaption provides comprehensive coverage of neurobehavioral disorders in children and adults following impact and acceleration accidents. Drawing on his training, education, and experience in human physiology, neuroanatomy, and endocrinology, the author not only gives readers a solid foundation for understanding, diagnosing, and treating concussive brain trauma, but also gives them tools to increase standards of care.

Topics include: • Post-concussive syndrome, biomechanical causes of trauma, and acute and chronic phases of co-morbid brain and somatic injury • The physiological basis for behavior and posttraumatic dysregulation of systems • Disorders related to pain, sensation, and motor activities • Headaches, consciousness, cognition, cerebral personality, and psychodynamic disorders • Developmental effects of children's concussive injury • Blast injuries characteristic of modern war • Unfamiliar signs not included in the usual list of post-concussive symptoms

Contents: Concussion: Not Always "Minor" Head Injury Introduction to the Postconcussion Syndrome The Central Nervous System: Organization of Behavior Acute Alterations of Consciousness The Internal Milieu: Brain and Body Biomechanics and Tissue Injuries Acute Brain and Somatic Injury The Acute Stress Response Chronic Posttraumatic Stress: Injury, Disease, and Burnou Comorbid Posttraumatic Stress Disorder and Concussion Disorders of Sensation, Motion, and Body Schema Vocal Motor Disorders Chronic Pain and Posttraumatic Headaches Chronic Posttraumatic Disorders of Consciousness Cognition, Language, and Intelligence Posttraumatic Personality Disorders ...

Catalog no. 8039, September 2011, 879 pp.

ISBN: 978-0-8493-8039-6, $179.95 / £112.00 Also available as an eBook

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KMN05_5.5x8.5_MC_Temp 10/2/14 10:37 AM Page 25

Neuropsychology / Neuropsychiatry Advances in the Neuroscience of Addiction Edited by

Cynthia M. Kuhn Duke University Medical Center, Durham, North Carolina, USA

George F. Koob The Scripps Research Institute, La Jolla, California, USA

Advances in the Neuroscience of Addiction provides an overview of the available and emerging approaches used to investigate the biologic mechanisms of drug addiction. It also delineates the research possibilities in relapse prevention.

The book begins with the three main environmental stimuli that trigger relapse—classical conditioning, stress, and neuroadaptive dysregulation induced by chronic drug use. It then discusses chronic extracellular recording and intravenous drug self-administration procedures, which enable researchers to characterize the discharge patterns of single neurons during drugdirected instrumental behavior. Exploring advances in voltammetry and enzyme-linked biosensors for measuring glutamate, the book discusses the theoretical background and results of neuroimaging studies related to neuronal networks activated by drug-specific cues. It then presents drug self-administration studies implementing modern genetic approaches to manipulate target proteins in mice.

The book illustrates how a neuroeconomic approach can inform studies of reward processing, particularly with addiction. It is a comprehensive introduction to the methodologies of the field for students and beginning researchers and an essential reference source for established investigators.

Selected Contents:

Methods of Behavior Analysis in Neuroscience Second Edition Edited by

Jerry J. Buccafusco Medical College of Georgia, Augusta, USA

A comprehensive reference for the most well-studied behavioral approaches in animal subjects, this book examines disease effects and therapeutic treatments.

The second edition features material on the relevance of transgenic mouse models for Alzheimer’s disease, behavioral methods for assessing the cognitive impairment associated with major psychotic disorders, the revival of the scopolamine reversal model for assessing the clinical relevance of new AD drugs, and new approaches for assessing cognitive impairment in aged mice. Each chapter presents theoretical background, methodology, and data interpretation.

Catalog no. 52349, October 2008, 360 pp ISBN: 978-1-4200-5234-3, $169.95 / £117.00 Also available as an eBook

A Theory of the Basal Ganglia and Their Disorders Robert Miller University of Otago, Dunedin, New Zealand

Advances in Animal Models of Relapse for Addiction Research Application of Chronic Extracellular Recording Method to Studies of Cocaine Self-Administration: Method and Progress Neurochemistry of Addiction: Monitoring Essential Neurotransmitters of Addiction Alcohol Craving and Relapse Prediction: Imaging Studies Integrating Behavioral and Molecular Approaches in Mice: Self-Administration Studies Neuroeconomics: Implications for Understanding the Neurobiology of Addiction

Although there is a wealth of information available on basal ganglia, this research field remains controversial due in part to the diverse number of disciplines involved. This book provides a cogent view of basal ganglia that integrates evidence from the basic neurosciences, neurology, and psychiatry. The first part of the text develops a conceptual theory based on the normal function of basal ganglia.

The second section details the mechanisms that relate basic pathology to the manifestation of symptoms for related disorders, including Huntington's disease, Parkinson's disease, dopamine-related psychosis, and other psychotic disorders.

Catalog no. 7391, April 2010, 238 pp.

ISBN: 978-0-8493-7391-6, $159.95 / £102.00 Also available as an eBook

Catalog no. 58975, August 2007, 312 pp.

ISBN: 978-1-4200-5897-0, $210.00 / £133.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Pain Management Coming Soon!

Maldynia

Acute Pain Management

Multidisciplinary Perspectives on the Illness of Chronic Pain

A Practical Guide, Fourth Edition Pamela E. Macintyre Royal Adelaide Hospital, South Australia

Stephan A. Schug University of Western Australia, Perth

This text focuses on practical acute pain management in adults. Providing up-to-date and evidence-based information, it demonstrates a range of treatment strategies that can be safely and effectively applied to individual patients as well as on a hospital-wide basis.

The book helps identify and assist in the management of more complex patients, where effective treatment can often be more challenging and where patients can run the risk of suboptimal care.

Acute Pain Management: A Practical Guide, Fourth Edition explores the mechanisms of action, efficacy, and adverse effects of local anesthetic drugs. It covers opioids, their side effects, and dosing requirements. It also discusses the effects of untreated severe pain. The book includes an updated set of multiple-choice questions to help readers test their assimilation of the material.

Contents: Introduction Organizational Considerations Assessment of the Patient with Acute Pain Pharmacology of Opioids Pharmacology of Local Anesthetic Drugs Non-Opioid and Adjuvant Analgesic Agents Routes of Systemic Opioid Administration and Titration Patient-Controlled Analgesia Epidural and Intrathecal Analgesia Other Regional and Local Analgesia Non-Pharmacological Therapies Acute Neuropathic and Persistent Postacute Pain Non-Surgical Acute Pain More Complex Patients Acute Pain Management after Discharge Self-Assessment Questions Catalog no. K22954, December 2014, c. 292 pp.

Pack - Book and Ebook, ISBN: 978-1-4822-3349-0 $69.95 / £44.99

Edited by

James Giordano Neuroethics Studies Program, Pellegrino Center for Clinical Bioethics, Georgetown University, Washington, D.C., USA and Potomac Institute for Policy Studies, Arlington, Virginia, USA

An in-depth examination of chronic pain, this book explores pain as a bio-cultural phenomenon that necessitates reexamination of medical philosophy, ethics, education, and practice. It provides a historical account of pain and then frames it with contemporary neurobiological perspectives. The book illustrates how what we know about pain could influence medical education and practice and demonstrates how knowledge of the history and present considerations of pain might help to construct meaningful, patient-centered medicine.

Catalog no. K11642, December 2010, 280 pp.

ISBN: 978-1-4398-3630-9, $179.95 / £112.00 Also available as an eBook

Translational Pain Research From Mouse to Man Edited by

Lawrence Kruger University of California, Los Angeles, USA

Alan R Light University of Utah, Salt Lake City, USA

Advances in molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its therapeutic applications. This book brings together recent advances in modern neuroscience, genetic studies in mice and humans, and the results of clinical trials. The authors examine rodent models for pain associated with bone cancer, osteoarthritis, and cardiac episodes. They discuss the cloning of highly specific receptors and the analysis of modular molecular mechanisms relevant to painful neuropathies. The book also considers the trend toward translational research in the commercial pharmaceutical industry.

Catalog no. K10609, November 2009, 432 pp.

ISBN: 978-1-4398-1209-9, $169.95 / £124.00 Also available as an eBook

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KMN05_5.5x8.5_MC_Temp 10/2/14 10:38 AM Page 27

Practical Resources for Understanding Neuroscience Coming Soon!

Atlas of Functional Neuroanatomy Third Edition Walter Hendelman, M.D. University of Ottawa, Ontario, Canada

• Presents a clear visual guide to understanding the human central nervous system • Approaches the topic from a functional perspective • Provides clinical problems with corresponding answers • Contains a glossary and illustrations throughout • Includes access to an author-supported website PowerPoint® slides are available with qualifying course adoption

Catalog no. K19088, May 2015, c. 403 pp.

Soft Cover, Pack - Book and eBook ISBN: 978-1-4665-8534-8, $69.95 / £44.99 See page 10

Neurophysiology A Conceptual Approach, Fifth Edition Roger Carpenter Gonville and Caius College, Cambridge, UK

Benjamin Reddi Royal Adelaide Hospital and University of Adelaide, Australia

• Supplies content that corresponds with modern undergraduate curricula • Integrates the principles of neuroscience with clinical manifestations • Covers developments in imaging technologies, genetics/genomics, and the enteric nervous system • Features color illustrations throughout Includes access to a companion website with self-assessment material and the highly acclaimed NeuroLab resources

Catalog no. K16924, August 2012, 448 pp.

Pack - Book and eBook ISBN: 978-1-4441-3517-6, $54.95 / £34.99 Also available as an eBook See page 10

KMN05_5.5x8.5_MC_Temp 10/2/14 10:38 AM Page 28

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