Small Molecules
Small Molecules PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
SIZE B PRICE
POTENTIAL USE
PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
SIZE B PRICE
POTENTIAL USE
(+)-BAY-K-8644
98791-67-4
9876741
L-type Ca2+channel blocker
Agonist
1mg
$95.00
10mg
$235.00
Exhibits negative vasodilatory and inotropic effects.
All-Trans Retinoic Acid
302-79-4
3027949
Retinoic acid receptors agonist
Agonist
50mg
$35.00
1g
$95.00
(-)-Blebbistatin
856925-71-8
8567182
Myosin II ATPase activity inhibitor
Inhibitor
1mg
$35.00
5mg
$140.00
Blocks cell blebbing and disrupst cytokinesis.
Promotes the differentiation of embryonic cells into motor neurons, pancreatic progenitors and cardiomyocytes.
AM 580
102121-60-8
1026081
RARα agonist
Agonist
10mg
$110.00 25mg
$240.00
(Z)-4-Hydroxytamoxifen
68047-06-3
6800637
Estrogen receptor modulator
Inhibitor
5mg
$120.00 25mg
$360.00
Activates intein-linked inactive Cas9.
Promotes the reprogramming of somatic cells to induced pluripotent stem cells and inhibits tumor cell proliferation.
1-Oleoyl Lysophosphatidic Acid (sodium salt)
22556-62-3
2256236
LPA1 and LPA2 receptor agonist
Agonist
1mg
$15.00
10mg
$100.00
Acts as growth stimulator of a variety of cell lines and a modulator of cell differentiation .
BAY 11-7082
19542-67-7
1956772
E2 ubiquitin (Ub) conjugating enzyme inhibitor
Inhibitor
10mg
$85.00
25mg
$195.00
11,12-EET
123931-40-8
1234083
Epithelial Na channels Inhibitor
Inhibitor
25ug
$40.00
100ug
$130.00
Assist in the recovery of Ca2+ depleted cells.
Induce apoptosis in several B and T lymphoma cell lines and TNF-alpha induced expression of several adhesion molecules.
BI-D1870
501437-28-1
5012813
RSK 1-4 inhibitor
Inhibitor
1mg
$50.00
10mg
$295.00
2-NBDG
186689-07-6
1860768
Fluorescentlylabeled deoxyglucose analog
Fluorescent indicator
1mg
$35.00
10mg
$265.00
Used to monitor glucose uptake in living cells.
Prevents PMA-induced TSC2 phosphorylation.
BIO
667463-62-9
6676296
GSK-3 inhibitor
Inhibitor
10mg
$155.00 25mg
$345.00
SREBPs inhibitor
Inhibitor
5mg
Activates ABCA1 signaling, immunomodulation, and suppresses macrophage differentiation.
Activates the Wnt signaling pathway and promotes selfrenewal in human and mouse cells.
BIRB 796 (Doramapimod)
285983-48-4
2854848
p38 MAPK inhibitor
Inhibitor
5mg
$85.00
25mg
$330.00
Promotes the maintenance of cell lines by inducing selfrenewal.
BrdU
59-14-3
5911439
Thymidine analog
Synthetic nucleoside
250mg
$35.00
1g
$85.00
Promotes chemical induction of mouse iPSCSs.
Brefeldin A
20350-15-6
2031560
Protein translocation from the ER to the Golgi apparatus inhibitor
Inhibitor
5mg
$40.00
25mg
$105.00
Induces autophagy in mammalian cells.
Calcitriol
32222-06-3
3220632
VDR activator
Activator
1mg
$75.00
10mg
$525.00
Increases the uptake of calcium from the gut into the blood and inhibits cell proliferation.
cAMP
60-92-4
6099240
Protein kinases activator
Activator
1g
$145.00 5g
$555.00
Regulates calcium channels.
Cardiogenol C hydrochloride
671225-39-1
6713912
Diaminopyrimidine compound
Activator
1mg
$30.00
10mg
$155.00
Induces Cardiomyocyte Differentiation.
CD 437
125316-60-1
1256011
Retinoic acid receptor agonist
Agonist
10mg
$105.00 50mg
$435.00
Induce apoptosis and arrests cell cycle activity in a variety of cancer lines.
CH 223191
301326-22-7
3012272
AhR antagonist
Antagonist
10mg
$145.00 50mg
$600.00
Exhibits pro-proliferative properties.
CHIR 98014
556813-39-9
5563993
GSK-3 inhibitor
Inhibitor
5mg
$165.00 25mg
$610.00
Improves glucose disposal and reduces tau phosphorylation in neurons.
CHIR 99021
252917-06-9
2520691
GSK-3 inhibitor
Inhibitor
1mg
$40.00
10mg
$155.00
Maintain human and mouse stem cell lines and, in combination with other reagents, chemically reprograms somatic cells into stem cells.
Clozapine N-oxide
34233-69-7
3426973
Clozapine metabolite
Activator
10mg
$125.00 25mg
$270.00
Activates DREAD receptors.
CNQX
115066-14-3
1151436
AMPA/Kainate receptor antagonist
Inhibitor
10mg
$70.00
$260.00
Blocks the excitatory action of kainate and quisqualate on spinal neurons.
25-hydroxy Cholesterol
2140-46-7
2144674
$35.00
25mg
$120.00
2’3’-cGAMP
144119066-4
1446640
STING agonist
Agonist
500ug
$275.00 1mg
$525.00
Induces the production of IFNBeta.
3-Deazaneplanocin A
102052-95-9
1029595
Histone h3 lysine 27 trimethylation inhibitor
Inhibitor
1mg
$160.00 5mg
$435.00
Used in generation of chemically induced pluripotent stem cells and to induce apoptosis in cancer cells.
3-Methyladenine
5142-23-4
5142342
PI3k inhibitor
Inhibitor
50mg
$55.00
100mg
$100.00
Inhibits autophagy and apoptosis.
4-Hydroxytamoxifen
68392-35-8
6833585
Estrogen receptor modulator
Inhibitor
10mg
$65.00
50mg
$240.00
Exhibits antiestrogenic and estrogenic activity.
5-Azacytidine
320-67-2
3206727
DNA methyltransferase inhibitor
Inhibitor
50mg
$20.00
250mg
$75.00
Inhibits the proliferation of several cancer cell lines, enhances the differentiation of embryonic stem cells into cardiomyocytes and resets the epigenetic memory of mouse IPS cells.
8-Bromo-cAMP
23583-48-4
2354843
Protein kinases activator
Agonist
25mg
$100.00 100mg
$300.00
Enhances the induction of pluripotency in human fibroblast cells.
9-cis-Retinoic acid
5300-03-8
5300380
Retinoic acid receptor and the retinoid X receptor activator
Activator
1mg
$40.00
5mg
$105.00
Promotes oligodendrocyte precursor cell differentiation and myelination.
A 83-01
909910-43-6
9094360
ALK5, ALK4 and ALK7 inhibitor
Inhibitor
10mg
$65.00
25mg
$215.00
Inhibits differentiation in iPSCs.
AICAR
2627-69-2
2626926
AMPK activator
Activator
50mg
$50.00
100mg
$90.00
Promotes promote osteogenic and astroglial differentiation.
ALK5 Inhibitor
446859-33-2
4463325
TGF-Beta receptor inhibitor
Inhibitor
5mg
$80.00
10mg
$140.00
Enhances the efficiency of cellular reprogramming and induces induce the differentiation of pancreatic progenitor cells into insulin-producing cells.
2
3
50mg
Small Molecules PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
CUR-61414
334998-36-6
3343668
SMO antagonist
Inhibitor
5mg
$110.00 10mg
Cyclic Pifithrin-Alpha Hydrobromide
511296-88-1
5118819
p53 inhibitor
Inhibitor
10mg
Cyclopamine
4449-51-8
4445185
Hedgehog signaling pathway inhibitor
Inhibitor
1mg
NMDA antagonist
Inhibitor
D-AP5
79055-68-8
7908985
5mg
POTENTIAL USE
PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
$205.00
Blocks proliferation and induces apoptosis in cancer cells.
Filipin III
480-49-9
4804999
Binds to cholestrol
Fluoresecent 1mg indicator
$140.00 5mg
$550.00
Histochemical stain for cholesterol.
$105.00 50mg
$425.00
Increases the efficiency of inducing pluripotent stem cells.
Forskolin
66575-29-9
6652995
cAMP pathway activator
Activator
10mg
$70.00
50mg
$135.00
$20.00
$95.00
Induces the differentiation of stem cells into endocrine cells and various anti-cancer applications.
Induces neuronal differentiation in stem cells and can be used to embryonic fibroblasts to induced pluripotent stem cells.
FTY720
162359-56-0
1625605
Sphingosine-1phosphate receptor modulator
Inhibitor
50mg
$60.00
100mg
$110.00
Sequesters lymphocytes in lymph nodes, inhibits cPLA2, and antagonizes cannabinoid receptor.
G-1
881639-98-1
8819813
GPR30 receptor agonist
Agonist
10mg
$165.00 25mg
$380.00
Inhibits the production of lipopolysaccharide (LPS) induced cytokines such as IL-6 and TNFalpha.
$50.00
SIZE B PRICE
10mg
50mg
$400.00
Used in the research of synaptic plasticity. More potent than D-AP5.
CATEGORY
SIZE A
PRICE
SIZE B PRICE
POTENTIAL USE
DAPI (Hydrochloride)
28718-90-3
2879038
Binds to the A-T rich regions of DNA
Fluoresecent 5mg indicator
$45.00
25mg
$155.00
Stain DNA and chromosomes for fluorescent microscopy and flow cytometry applications.
G-15
1mg
$60.00
25mg
$350.00
2088055
Gamma-secretase complex inhibitor
Inhibitor
$150.00 50mg
$620.00
Promotes neuronal differentiation and enhances the apoptosis of human tongue carcinoma cells.
GPR30 receptor antagonist
Antagonist
208255-80-5
116100205-6
1160560
DAPT
Opposes the physiological effects of estrogen and inhibit calcium mobilization in vitro.
Garcinol
78824-30-3
7883034
Inhibitor
10mg
$90.00
25mg
$210.00
Promotes the ex vivo expansion of human stem cells.
Inhibits mature dendritic cell differentiation and promotes the differentiation of human mesenchymal cells.
Histone acetyltransferase (HAT) PCAF and p300 inhibitor
Gatifloxacin
112811-59-3
1125931
Bacterial DNA gyrase and topoisomerase IV inhibitor
Inhibitor
1g
$40.00
10g
$310.00
Promotes self-renewal in cultured embryonic stem cells.
Go 6983
133053-19-7
1331975
Protein kinase C inhibitor
Inhibitor
1mg
$40.00
10mg
$200.00
Inhibits differentiation and maintains the pluripotency of embryonic stem cells.
Dexamethasone
50-02-2
5000222
Glucocorticoid
Inhibitor
10mg
500mg
$45.00
5g
$245.00
Dibutyryl-cAMP, sodium salt
16980-89-5
1698950
Protein kinases activator
Activator
50mg
$50.00
250mg
$220.00
Induces neurite growth
DL-AP5
76326-31-3
7633136
NMDA antagonist
Inhibitor
10mg
$65.00
50mg
$270.00
Used in the research of synaptic plasticity.
DMOG
89464-63-1
8946314
P4H inhibitor
Inhibitor
10mg
$20.00
50mg
$70.00
Promotes cell survival under hypoxic conditions.
GSK923295
108896537-0
1083707
CENP-E inhibitor
Inhibitor
5mg
$140.00 50mg
Docosahexaenoic acid (DHA)
6217-54-5
6215455
Retinoid X receptor agonist
Agonist
100mg
$60.00
250mg
$135.00
Modulates the carrier-mediated transport of glycine, taurine, and choline.
$1,000.00 Inhibits tumor cell growth, which is further enhanced when MEK/ ERK signaling is also inhibited.
GW 4064
278779-30-9
2783097
Selective Farnesoid X receptor agonist
Agonist
1mg
$30.00
10mg
$120.00
Assists in the study of the biological role of FXR.
Dorsomorphin
866405-64-3
8666430
BMP pathway inhibitor
Inhibitor
10mg
$140.00 50mg
$430.00
Promotes specific cell differentiation and induces cancer cell line autophagy.
GW 9662
22978-25-2
2292528
PPARgamma antagonist
Antagonist
10mg
$75.00
50mg
$310.00
Blocks the differentiation of monocytes to osteoclasts.
Doxycycline hyclate
24390-14-5
2431450
Matrix metalloproteases inhibitor
Inhibitor
1g
$30.00
10g
$125.00
Regulates inducible gene expression in Tet-ON/Off systems.
GW2580
870483-87-7
8708778
cFMS kinase inhibitor
Inhibitor
5mg
$75.00
25mg
$280.00
Blocks colony stimulating factor 1 (CSF-1) signaling and monocyte growth.
EC 23
104561-41-3
1044131
Photostable synthetic ATRA analog
Agonist
5mg
$70.00
25mg
$245.00
Induces differentiation of stem cells.
HA-100 Dihydrochloride
210297-47-5
2104759
Protein kinase inhibitor
Inhibitor
5mg
$65.00
25mg
$295.00
EHNA hydrochloride
58337-38-5
5833857
PDE2 inhibitor
Inhibitor
5mg
$30.00
25mg
$125.00
Inhibits spontaneous differentiation of stem and neuronal cells.
Aids in the survivability of pluripotent stem cells and useful in increasing the efficiency of the chemical reprogramming of human fibroblasts.
HPI-1
599150-20-6
5992065
Hedgehog signaling pathway inhibitor
Inhibitor
10mg
$160.00 50mg
$655.00
Inhibits the proliferation of SmoM2 expressing cell lines.
IBMX
28822-58-4
2885842
Cyclic nucleotide phosphodiesterases inhibitor
Inhibitor
100mg
$35.00
$145.00
Increases cell differentiation, decreases proliferation, and induces apoptosis.
ID-8
147591-46-6
1474669
Tyrosine phosphorylationregulated kinases inhibitor
Inhibitor
10mg
$100.00 25mg
$220.00
Maintain the pluripotency and sustains the self-renewal of stem cells.
endo-IWR-1
112744282-3
1128234
Wnt pathway inhibitor
Inhibitor
10mg
$115.00 50mg
$480.00
Maintains pluripotency of human embryonic stem cells when used with CHIR99021 and promotes Beta-catenin phosphorylation.
Estradiol
50-28-2
5022822
Estrogen receptor agonist
Agonist
1g
$30.00
10g
$150.00
ERalpha and ERbeta receptors activator.
EX 527
49843-98-3
4989833
SIRT1 inhibitor
Inhibitor
1mg
$30.00
10mg
$85.00
Increases insulin sensitivity and effects other metabolic regulatory functions.
4
5
1g
Small Molecules BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
SIZE B PRICE
POTENTIAL USE
PRODUCT NAME
CAS #
116092748-9
1164899
TGF-beta signaling pathway activator
Activator
1mg
$55.00
10mg
$190.00
Induces definitive endoderm formation in human and mouse embryonic stem cells.
LDN193189 Hydrochloride
113646693-7
1139374
TGF-beta signaling pathway activator
Activator
1mg
$35.00
10mg
$185.00
Induces definitive endoderm formation in human and mouse embryonic stem cells.
PRODUCT NAME
CAS #
IDE1
IDE2
Imatinib Mesylate
Ionomycin Calcium Salt
IQ-1
IWP-2
IWP-3
220127-57-1
56092-82-1
331001-62-8
686770-61-6
687561-60-0
2205712
5608212
3316280
6866167
6876006
Tyrosine-kinase inhibitor
Inhibitor
Calcium ionophore
Activator
Beta-catenin/p300 signaling inhibitor
Wnt pathway inhibitor
Wnt pathway inhibitor
Inhibitor
Inhibitor
Inhibitor
25mg
1mg
10mg
1mg
1mg
$35.00
$20.00
100mg
10mg
$160.00 50mg
$30.00
$35.00
10mg
10mg
$95.00
$135.00
$705.00
$155.00
$200.00
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
SIZE B PRICE
POTENTIAL USE
106236862-0
1066208
BMP pathway inhibitor
Inhibitor
5mg
$85.00
25mg
$330.00
Promotes specific cell differentiation.
LGK974
124324414-5
1241454
PORCN inhibitor
Inhibitor
1mg
$65.00
5mg
$180.00
Blocks carcinogenesis.
Lipoxin A4
89663-86-5
8968653
Activator
25ug
$185.00 100ug
$655.00
Inhibits stem cell proliferation and erythropoiesis.
potent kinase C activator
Inhibits the cytotoxicity of NK cells.
LY-364947
396129-53-6
3965362
Inhibitor
5mg
$85.00
10mg
$160.00
Stimulate the intracellular production of IL-2, IL-4 and perforin.
TGF-Beta pathway inhibitor
Inhibits certain cancer cells and blocks chondrogenesis in human stem cells.
LY-411575
209984-57-6
2095768
Inhibitor
5mg
$90.00
25mg
$375.00
Maintains embryonic cell pluripotency in Wnt3a-treated cells and prevents spontaneous differentiation.
y-secretase inhibitor
Exhibits anti-cancer properties and is capable of promoting goblet cell differentiation in mouse organoids.
LY2157299
700874-72-2
7007224
TGF-BetaR inhibitor
Inhibitor
5mg
$175.00 50mg
$755.00
Inhibit the migration and tumor growth of hepatocellular carcinoma cell lines.
LY294002
154447-36-6
1543664
PI3Ks inhibitor
Inhibitor
5mg
$40.00
25mg
$170.00
Promotes the differentiation of insulin-producing cells from embryonic cells and inhibits the growth of ovarian carcinomas.
Metformin hydrochloride
1115-70-4
1117045
AMPK pathway Activator
Activator
1g
$25.00
5g
$35.00
Promotes neurogenesis.
MK 886 sodium salt
118427-55-7
1185572
Leukotriene biosynthesis inhibitor
Inhibitor
5mg
$85.00
25mg
$310.00
Induces antiproliferative effects and apoptosis in HL-60 cells.
MK-2206 dihydrochloride
103235013-2
1031320
Akt inhibitor
Inhibitor
5mg
$110.00 25mg
$385.00
Inhibits the proliferation of cancer cell lines when used synergistically with cytotoxic agents.
Monensin sodium salt
22373-78-0
2237803
Ionophore antibiotic
Inhibitor
1g
$45.00
10g
$385.00
Blocks intracellular protein transport.
N-Dodecanoyl-Lhomoserine lactone
137173-46-7
1374677
Involved in bacterium quorum sensing
Activator
5mg
$35.00
25mg
$150.00
Modules the immune system.
NBQX disodium salt
479347-86-9
4798694
AMPA receptor antagonist
Inhibitor
10mg
$140.00 50mg
$500.00
Exhibits neuroprotective and anticonvulsant properties.
Nelfinavir mesylate
159989-65-8
1596589
HIV-1 protease inhibitor
Inhibitor
10mg
$75.00
50mg
$300.00
Inhibits the growth of a variety of cancer types.
Nicotinamide
98-92-0
9899208
PARP-1 inhibitor
Inhibitor
50mg
$30.00
100mg
$50.00
Promote the formation and increases the lifespan of organoids.
Nocodazole
31430-18-9
3141890
Microtubule inhibitor
Inhibitor
10mg
$65.00
50mg
$215.00
Enhances homology-directed repair efficiency.
NS-398
123653-11-2
1231125
Cyclooxygenase-2 enzyme inhibitor
Inhibitor
10mg
$80.00
50mg
$335.00
Exhibits anti-inflammatory properties with potent analgesic and antipyretic effects.
NU 7441
503468-95-9
5039598
DNA-PK inhibitor
Inhibitor
10mg
$125.00 25mg
$275.00
Enhance the efficiency of CRISPR-Cas9 mediated homology-directed repair.
Inhibits embryonic stem cell self-renewal and promotes cardiomyocyte differentiation from human stem cells. Inhibits embryonic stem cell self-renewal and promotes cardiomyocyte differentiation from human stem cells.
IWP-4
686772-17-8
6861787
Wnt pathway inhibitor
Inhibitor
1mg
$35.00
10mg
$300.00
Inhibits embryonic stem cell self-renewal and promotes cardiomyocyte differentiation from human stem cells.
Kainic Acid Monohydrate
58002-62-3
5806232
Kainate receptors agonist
Agonist
10mg
$105.00 50mg
$435.00
Potent neuroexcitatory amino acid and neurotoxin in high doses.
Kartogenin
4727-31-5
4723153
Filamin A activity inhibitor
Inhibitor
10mg
$105.00 25mg
$235.00
Induces cartilage differentiation and potently induces human mesenchymal stem cells into chondrocytes.
Kenpaullone
142273-20-9
1422097
Glycogen synthase kinase 3Beta and CDK1/Cyclin B inhibitor
Inhibitor
1mg
$45.00
$165.00
Enhances the chemical reprogramming of induced pluripotent stem cells from somatic cells.
10mg
KY02111
111880713-8
1111388
Wnt pathway inhibitor
Inhibitor
10mg
$110.00 50mg
$395.00
Promotes the differentiation of human pluripotent stem cells to cardiomyocytes.
L-161,982
147776-06-5
1470657
EP4 receptor antagonist
Antagonist
1mg
$30.00
10mg
$240.00
Inhibits PGE2-induced bone formation in rats and the antiinflammatory properties of PGE2 in human macrophages.
L-755,507
159182-43-1
1594312
β3 adrenergic receptor partial agonist
Agonist
10mg
$165.00 50mg
$715.00
Enhances CRISRP-mediated homology-directed efficiency.
Cav3.2 channels Inhibitor
Inhibitor
L-Ascorbic Acid
LDN193189
50-81-7
106236824-4
5088177
1062443
BMP pathway inhibitor
Inhibitor
6
100g
1mg
$35.00
$40.00
250g
10mg
$80.00
$235.00
Enhances the generation of human and mouse chemically induced PSCs and enhances the differentiation of embryonic stem cells into cardiac myocytes. Promotes specific cell differentiation.
7
Small Molecules PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
POTENTIAL USE
PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
SIZE B PRICE
POTENTIAL USE
OAC-1
300586-90-7
3009078
OCT-4 activator
Activator
10mg
$145.00 25mg
$325.00
Enhances the efficiency of reprogramming embryonic fibroblasts.
Rapamycin
53123-88-9
5318893
mTOR pathway inhibitor
Inhibitor
1mg
$35.00
10mg
$125.00
Blocks protein synthesis, arrests cell cycle progression, and inhibits IL-2 signal transduction mechanisms.
PD 0325901
391210-10-9
3911091
MEK1 and MEK2 inhibitor
Inhibitor
10mg
$110.00 25mg
$220.00
Used with CHIR99021 to reprogram somatic cells into iPS cells and promote cell selfrenewal.
Resveratrol
501-36-0
5013606
COX-1 inhibitor
Inhibitor
100mg
$40.00
500mg
$130.00
Exhibits anti-inflammatory and antiproliferative properties that interferes with carcinogenesis.
PD 173074
219580-11-7
2191178
FGFR1 and FGFR3 inhibitor
Inhibitor
10mg
$110.00 25mg
$220.00
Suppresses the differentiation of mouse embryonic cells and promotes the survival of human embryonic cells.
Reversine
656820-32-5
6563252
Adenosine A3 receptor, MEK1, and Aurora B kinase inhibitor
Inhibitor
5mg
$140.00 25mg
$540.00
De-differentiates myoblasts to stem cell progenitors with adipogenic and osteogenic potential.
PD 98059
167869-21-8
1672186
MKK inhibitor
Inhibitor
10mg
$75.00
50mg
$290.00
Enhance the self-renewal of embryonic stem cells and blocks the osteogenic differentiation of human mesenchymal stem cells.
RG108
48208-26-0
4822608
Non-nucleoside DNA methyltransferase inhibitor
Inhibitor
10mg
$105.00 50mg
$435.00
Reactivates epigenetically silenced tumor suppressor genes and enhances the reprogramming efficiency of induced pluripotent stem cells.
Phorbol 12-myristate 13-acetate (PMA)
16561-29-8
1652981
PKC activator
Activator
1mg
$40.00
5mg
$95.00
Promotes tumors and induces the activation of many cell types to produce cytokines wit PMA.
Rosiglitazone
122320-73-4
1227342
PPARÎł agonist
Agonist
10mg
$35.00
50mg
$120.00
Stimulates cell differentiation and proliferation.
Pifithrin-mu
64984-31-2
6493124
p53 inhibitor
Inhibitor
10mg
$70.00
25mg
$165.00
Increases the efficiency of inducing pluripotent stem cells and reduces radiation induced cell death.
RS-1
312756-74-4
3127446
RAD51 activator
Activator
10mg
$75.00
50mg
$290.00
Enhances homology-directed repair and CRISPR-Cas9 knock-in efficiency.
Pluripotin
839707-37-8
8393780
RasGAP and ERK1 inhibitor
Inhibitor
1mg
$50.00
10mg
$250.00
Promotes cellular self-renewal.
Ruxolitinib
941678-49-5
9414958
Janus-associated Kinase inhibitor
Inhibitor
5mg
$135.00 25mg
$350.00
Blocks IL-6 signaling and inhibits the proliferation of erythroid progenitors.
PluriSln 1
91396-88-2
9138826
SCD1 inhibitor
Inhibitor
10mg
$100.00 50mg
$270.00
Selectively eliminates undifferentiated human pluripotent stem cells.
SAG
912545-86-9
9128694
Smoothened protein in the hedgehog signaling pathway agonist
Agonist
1mg
$100.00 5mg
$440.00
Prostaglandin D2
41598-07-6
4150768
Major prostaglandin produced by mast cells and is the primary prostaglandin in the brain
Activator
1mg
$40.00
$320.00
Causes vasodilation, induces inflammation, and its presence in hair follicles may be partially responsible for male pattern baldness.
Enhances the neuronal differentiation of human induced pluripotent stem cells and aids in the survival and proliferation of neuronal precursors.
SAHA
149647-78-9
1497894
Pan-histone deacetylase inhibitor
Inhibitor
250mg
$50.00
1g
$170.00
Halts the growth of transformed cells, induces apoptosis in T cell lymphoma, and arrests cancer cell growth.
SB 202190
152121-30-7
1523072
p38 MAP kinases inhibitor
Inhibitor
10mg
$30.00
25mg
$55.00
Induces cardiomyocyte differentiation from human embryonic stem cells and increases neural stem cell selfrenewal.
SB 203580
152121-47-6
1524762
p38 inhibitor
Inhibitor
5mg
$90.00
50mg
$690.00
Exhibits anti-proliferative activity on cytokine-activated lymphocytes and enhances cardiomyocyte differentiation.
SB 203580 hydrochloride
869185-85-3
8698538
p38 inhibitor
Inhibitor
10mg
$190.00 25mg
$450.00
Exhibits anti-proliferative activity on cytokine-activated lymphocytes and enhances cardiomyocyte differentiation.
SB 216763
280744-09-4
2800944
GSK-3 inhibitor
Inhibitor
10mg
$125.00 50mg
$520.00
Maintains the undifferentiated state of mouse embryonic stem cells.
SB 431542
301836-41-9
3014193
ALK5, ALK4 and ALK7 inhibitor
Inhibitor
1mg
$20.00
10mg
$120.00
Promotes stem cell differentiation by suppressing cell renewal through the blocking of Smad signaling.
SB 525334
356559-20-1
3562015
ALK5 inhibitor
Inhibitor
10mg
$125.00 50mg
$485.00
Attenuates bleomycin-induced pulmonary fibrosis.
SIZE B PRICE
10mg
Prostaglandin E2
363-24-6
3632464
Most biologically active prostaglandin
Activator
10mg
$105.00 50mg
$475.00
Involved in smooth muscle relaxation, inflammation, fertility, sleep cycle regulation, and gastric mucosal integrity.
Purmorphamine
483367-10-8
4831086
Smoothened protein in the hedgehog signaling pathway activator
Activator
1mg
$25.00
10mg
$195.00
Induces osteogenesis and influences the differentiation and growth of neurons.
Puromycin dihydrochloride
58-58-2
5855822
Protein synthesis inhibitor
Inhibitor
50mg
$50.00
500mg
$275.00
Inhibits translation and the transportation of protein into the mitochondria.
Pyrintegrin
122844538-2
1223824
Beta1 integrin activator
Activator
1mg
$75.00
10mg
$275.00
Aids in the survival of human embryonic stem cells after trypsin dissociation and enhance their adhesion to laminin and matrigel plates.
Q-VD-OPH
113569598-5
1139855
Caspace inhibitor
Inhibitor
1mg
$135.00
Raloxifene hydrochloride
82640-04-8
8260480
Estrogen receptor agonist
Agonist
50mg
$30.00
8
Prevents apoptosis mediated by the caspace 8/10, caspace 9/3, caspace 12 pathways. 250mg
$125.00
Enhances osteoblast differentiation and protects endothelial cells against oxidative stress.
9
Small Molecules PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
POTENTIAL USE
PRODUCT NAME
CAS #
BIOGEMS CAT # FUNCTION
CATEGORY
SIZE A
PRICE
SCR7 pyrazine
14892-97-8
1489782
DNA ligase IV inhibitor
Inhibitor
10mg
$165.00 25mg
$310.00
Increase the efficiency of homology-directed repair.
U0126
109511-58-2
1095821
MKK and MEK inhibitor
Inhibitor
5mg
$145.00 25mg
$560.00
Maintains human pluripotent stem cells in the undifferentiated state.
Sinomenine hydrochloride
6080-33-7
6083373
Anti-inflammatory plant alkaloid
Inhibitor
50mg
$30.00
500mg
$180.00
Promotes the self-renewal of embryonic stem cells.
Valproic acid sodium salt
1069-66-5
1066656
HDAC inhibitor
Inhibitor
25g
$50.00
100g
$155.00
$25.00
250g
$95.00
In combination with Activin A, sodium butyrate promotes the differentiation of hepatocytes from embryonic stem cells.
Promotes the self-renewal and differentiation of hematopoietic progenitor cells and enhances the generations of induced pluripotent stem cells, in combination with other small molecules and growth factors.
Sodium Butyrate
156-54-7
1565474
HDAC inhibitor
Inhibitor
50g
SP 600125
129-56-6
1295666
JNK inhibitor
Inhibitor
10mg
$60.00
50mg
$175.00
Prevents apoptosis in many cell lines and inhibits BMP-9 induced osteogenic differentiation of mouse mesenchymal stem cells.
XAV939
284028-89-3
2848932
TNKS 1 and 2 inhibitor
Inhibitor
10mg
$90.00
25mg
$195.00
Inhibitor
10mg
$105.00 50mg
$390.00
Inhibits neuronal hyperpolarization and chloride flux across the cell membrane.
Promotes cardiomyogenic development in progenitor cells, inhibits the proliferation of certain carcinoma cell lines, and enhances the induction of cortical interneurons from embryonic stem cells.
SR 95531 Hydrobromide
104104-50-9
1045090
GABAA receptor antagonist
Stauprimide
154589-96-5
1549658
c-Myc expression inhibitor
Inhibitor
500ug
$55.00
5mg
$270.00
Primes cells for further cellular differentiation.
Y-27632 Dihydrochloride
129830-38-2
1293823
ROCK inhibitor
Inhibitor
1mg
$50.00
10mg
$175.00
Diminishes dissociationinduced apoptosis, increases cloning efficiency, and improves embryoid body formation.
StemRegenin 1 (SR1)
122763349-9
1224999
Aryl hydrocarbon receptor antagonist
Antagonist
1mg
$50.00
10mg
$165.00
Promotes the self-renewal of human hematopoietic stem cells and stimulates the proliferation and differentiation of CD34+ hematopoietic progenitor cells into dendritic cells.
Zebularine
654065
3691061
DNA methylation inhibitor
Inhibitor
1mg
$25.00
10mg
$110.00
Induces the differentiation of mesenchymal stem cells into cardiomyocytes.
Zidovudine
30516-87-1
3058716
Reverse transcriptase inhibitor
Inhibitor
100mg
$80.00
1g
$170.00
Decreases CRISPR-mediated homology-directed repair efficiency.
SIZE B PRICE
SU5416
204005-46-9
2044690
VEGFR inhibitor
Inhibitor
10mg
$110.00 50mg
$470.00
Inhibits tumor vascularization and growth of multiple tumor types.
T 0901317
293754-55-9
2935595
High affinity liver X receptor agonist
Agonist
10mg
$30.00
50mg
$125.00
Lowers cholesterol levels in serum and liver and suppresses the proliferation of breast and prostate cancer cells.
Tamoxifen
10540-29-1
1052910
Estrogen receptor modulator
Activator
500mg
$50.00
5g
$400.00
Exhibits neuroprotective properties in female rats and is reported to block certain cancer cell growth.
Tetrodotoxin Citrate
18660-81-6
4362892
Sodium channel conductance inhibitor
Inhibitor
1mg
$160.00
Thiazovivin
122605671-8
1227180
ROCK inhibitor
Inhibitor
1mg
$45.00
10mg
$160.00
Greatly enhance the efficiency of generating induced pluripotent stem cells and promotes the survival of human embryonic stem cells during dissociation.
Tranylcypromine hydrochloride
1986-47-6
1984764
Histone demethylzation inhibitor
Inhibitor
50mg
$30.00
250mg
$70.00
Enhances the chemical reprogramming of murine fibroblasts to induced pluripotent stem cells.
Trichostatin A
58880-19-6
5881960
class I and II histone deacetylase inhibitor
Inhibitor
1mg
$105.00 10mg
$770.00
Increases the efficiency of the reprogramming of induced pluripotent stem cells and exhibits anti-cancer properties.
Retinoic acid receptor activator
Activator
TTNPB
71441-28-6
7142861
10
1mg
$40.00
Blocks muscle and nerve action potentials.
10mg
$155.00
Increases the efficiency of induced pluripotent stem cell (iPSC) chemical reprogramming.
Y-27632 (ROCK Inhibitor)
11
SIZE B PRICE
POTENTIAL USE
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