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Datasheet of L-165041
Description: L-165041 is a cell permeable PPARδ agonist which induces adipocyte differentiation in NIH-PPARδ cells. L-165041 displays more than 100-fold selectivity for both mouse and human PPARδ receptors over other subtypes. L-165041 reduces lipid accumulation in the liver and decreases total hepatic cholesterol and triglyceride content. L-165041 raises plasma cholesterol levels in vivo, in insulin-resistant db/db mice. L-165041 is neuroprotective in models of cerebral infarction and Parkinson's disease.
Chemical Information Catalog
DC2076
Purity of current batch:
>98%
Molecular Weight (MW)
402.44
Molecular Formula
C22H26O7
CAS No.
79558-09-1
Solubility (25°C)
DMSO
Storage
Store at -20°C (desiccating conditions).
Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.