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Datasheet of JWH-133
Description: JWH-133 is a potent CB2 selective agonist (Ki = 3.4 nM). Approx. 200-fold selective over CB1 receptors. Active in vivo, reducing spasticity in a murine model of multiple sclerosis. Activity also enhances the release of IL-10 by LPS/IFN-γ -stimulated macrophages and results in downregulation of the IL-12 subunit p40. For the detailed information about the solubility of JWH-133 in water, the solubility of JWH-133 in DMSO, the solubility of JWH-133 in PBS buffer, the animal experiment（test） of JWH-133,the in vivo,in vitro and clinical trial test of JWH-133,the cell experiment（test） of JWH-133,the IC50, EC50 and Affinity of JWH-133, please contact DC Chemicals..
Chemical Information Catalog
DC2077
Purity of current batch:
>98%
Molecular Weight (MW)
312.49
Molecular Formula
C22H32O
CAS No.
259869-55-1
Solubility (25°C)
DMSO
Storage
Store at -20°C (desiccating conditions).
Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.