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Datasheet of GW-7647
Description: GW 7647 is a potent PPARα agonist with 200-fold selectivity over PPARγ and PPARδ. This compound has also been found to cause an up-regulation of β-oxidation gene expression and an increase in palmitate oxidation. Additionally, glycolysis is strongly reduced at transcriptional levels by GW 7647 leading to a decrease in lactate and pyruvate production. Furthermore, this agent displays the ability to decrease glucose oxidation and inhibit lipogenesis and triglyceride esterification. For the detailed information about the solubility of GW-7647 in water, the solubility of GW-7647 in DMSO, the solubility of GW-7647 in PBS buffer, the animal experiment（test）of GW-7647,the in vivo,in vitro and clinical trial test of GW-7647,the cell experiment（test） of GW-7647,the IC50, EC50 and Affinity of GW-7647, please contact DC Chemicals...
Chemical Information Catalog
DC2078
Purity of current batch:
>98%
Molecular Weight (MW)
502.75
Molecular Formula
C29H46N2O3S
CAS No.
265129-71-3
Solubility (25°C)
DMSO
Storage
Store at -20°C (desiccating conditions).
Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.