Figure 1a below shows the patient outcomes in the overall MDR/RR-TB cohort in Minsk for the last years. From 2013 to 2018 there is a decrease in the number of patients enrolled into care and an increase in success rates - which is accompanied by a decrease in the treatment failure rate. LTFU and death rates remain fairly steady at around 10%.
BASELINE CHARACTERISTICS OF STUDY PATIENTS There were 59 patients included from the Minsk PS MDR/RR-TB intervention in this analysis, of which 8 (13.6%) were female and 51 (86.4%) were male. The majority of patients had a history of either past incarceration 41 (69.5%), homelessness 8 (13.6%) or unemploy-
ment 37 (62.7%). Amongst males, 21 (41.2%) were either married or living with a partner and the same figure for females was 5 (62.5%). Amongst patients for whom data was available, 24 i.e. 100% were recorded as being smokers. The full baseline social characteristics, stratified by whether the patient was adherent to tuberculosis treatment or not can be seen in Table 2.
TABLE 2: BASELINE SOCIAL CHARACTERISTICS BY ADHERENCE STATUS >=90% adherence (N=38) N (%)
<90% adherent (N=21) N (%)
Overall (N=59) N (%)
Gender
p value 0.142 (1)
- Female
7 (87.5)
1 (12.5)
8 (13.6)
- Male
31 (60.8)
20 (39.2)
51 (86.4)
Age group
0.106 (1) - <35
5 (62.5)
3 (37.5)
8 (13.6)
- 35-55
26 (74.3)
9 (25.7)
35 (59.3)
- >55
7 (43.8)
9 (56.2)
16 (27.1)
Marital Status
0.084 (1) - In union
16 (61.5)
10 (38.5)
26 (44.1)
- Single
13 (86.7)
2 (13.3)
15 (25.4)
Widowed/divorced/Separated
9 (50.0)
9 (50.0)
18 (30.5)
Education level
0.739 (1) - Did not finish school
1 (50.0)
1 (50.0)
2 (3.4)
- Secondary
35 (66.0)
18 (34.0)
53 (89.8)
- University
2 (50.0)
2 (50.0)
4 (6.8)
Employment status
0.924 (1) - Employed
14 (63.6)
8 (36.4)
22 (37.3)
- Unemployed
24 (64.9)
13 (35.1)
37 (62.7)
History of Incarceration
0.810 (1) - Yes
26 (63.4)
15 (36.6)
41 (69.5)
- No
12 (66.7)
6 (33.3)
18 (30.5)
Homeless status
0.501 (1) - Homeless
6 (75.0)
2 (25.0)
8 (13.6)
- Not homeless
32 (62.7)
19 (37.3)
51 (86.4)
- Yes
14 (58.3)
10 (41.7)
24 (100.0)
- No
0 (0)
0 (0)
0 (0)
Smoker
IV illicit drug use
10
0.416 (1) - Yes
1 (33.3)
2 (66.7)
3 (23.1)
- No
6 (60.0)
4 (40.0)
10 (76.9)
