Biotech Brochure

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BIOTECH BUILDING YOUR VISION


OUR GOAL Our Company is a team focused on one simple goal – your success. Our core philosophy remains consistent with each individual, and with each and every project - to deliver the highest quality product that exceeds our clients’ needs and expectations, while providing personal attention and extra care that distinguishes us from our competition.

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WE WORK HARDER TO MAKE YOUR JOB EASIER

OUR PHILOSOPHY BUILDING RELATIONSHIPS Our success is built on you, our Clients. We endeavor to make every encounter a positive and effective one, building trust to create a collaborative, lifelong partnership.

PROVIDING SOLUTIONS Our 40 years of experience gives us keen insight, allowing us to mitigate potential problems and proactively resolve issues with the best possible solutions.

CREATING VALUE Dome Construction is more than a builder and construction manager– we are construction partners. Our objective is to understand your vision and bring it to reality. From project inception through project completion and beyond, we are there to ensure a successful outcome.


OUR HISTORY FROM THE BEGINNING Dome Construction was founded in 1969 as a Construction Manager and General Contractor specializing in commercial renovation and new construction projects in the greater San Francisco Bay Area. Since then we have built our company by continually striving to improve our services and manage our projects with the highest standards. We want to ensure that our company is known for its commitment to excellence.

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Abgenix Corporation


OUR PEOPLE At Dome Construction, we’ve got you covered.

Our Vision is to “Be Your Contractor of Choice� and we aim to hire the best people. Whether a recent grad or seasoned professional, we help employees reach new heights through various peer support and training programs. We offer invaluable experience by offering the opportunity to work on innovative and challenging projects such as state of the art Life Science facilities, Biofuel research centers, specialized laboratories and complex Manufacturing Suites in the great San Francisco Bay Area and beyond. Our talented staff is comprised of over 170 individuals– individuals who share our core values and promote our core purpose. People that want to make a positive impact during their careers. People with a true passion for what they do. The construction process places extraordinary demands on project team members to reach high levels of communication, coordination, and documentation. These teams consist of highly trained construction professionals who work closely together over multiple projects, % & on their passion for the industry and dedication to long-term client relationships. They receive regular training to ensure that they are knowledgeable in the most recent construction and management innovations and technologies.

Stanford University | Arastradero Labs


FOCUS GROUP

BIOTECH

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) * ( +/23 cessful completion of this project, and the hundreds of subsequent projects, has established Dome Construction as a leader $

5 $ 8' : ; professionals who have the desire to work on these highly technical projects - projects that require unparalleled expertise, exacting coordination, exceptional client service, and attention to detail.

education

Our Focus Group conducts regular training sessions to assure that all members are knowledgeable in the latest innovations and construction requirements for planning of facilities. We invite experts from consulting engineers, subcontractors and specialty vendors to present seminars. This education process has created a highly knowledgeable and talented group of construction managers who successfully execute the construction of every project undertaken by Dome Construction.

evaluate

We constantly evaluate and improve upon our construction management techniques and procedures to make certain they are ' ( current projects and update our staff.

experience

Dome Construction offers a vast amount of experience in providing preconstruction and construction services. We are accustomed to working with owners, real estate agents, building managers, architects and tenants on a “team basis.� We understand that the ultimate success of any construction project is exclusively measured by Client satisfaction through superior project delivery. Our goal has always been to build long term relationships by exceeding client expectations. Consistently delivering successful projects, we have built unparalleled relationships with our Clients.


AREAS OF EXPERTISE Laboratory Specialists We have developed an extensive expertise in many different areas of laboratory projects. Biology or Chemistry, BSL, H-Room or any other project scope element – we understand the unique challenges and have developed methodologies to adjust our construction approach accordingly. Our in depth knowledge of typical lab equipment ensures that the supporting utility systems are designed, coordinated and constructed correctly.

cGMP Manufacturing We have extensive knowledge in constructing production facilities to cGMP regulatory standards. We have built both large and small scale facilities for Clinical and Commercial production operations. Our understanding of the validation process required for such facilities along with our commitment to superior quality ensures successful results on every project. One of our core areas of expertise ;<' < requires Dome’s extensive knowledge of execution and documentation requirements.

Equipment Purchasing ) = > the bidding process and evaluating bid results towards a Recommendation of Award to the client. We understand that the equipment procurement process can be critical to the overall project success and we will ensure that this process is integrated into the overall project execution planning.

Noise/Dust/Vibration Mitigation Many of our projects are being executed in mission critical facilities. We have a fantastic track record of implementing construction projects in occupied facilities without impact to ongoing operations. Proactive planning of construction barricades, Lock-out / Block-outs to isolate utilities combined with careful scheduling and coordination of all invasive construction activities, are key requirements on many of our projects.

Shutdowns (Minimal Disruption) Carefully planned and executed shutdowns for critical utility tie-ins have become routine elements on most of our projects. Our clients can rely on us to meet our timelines and get critical utilities back in operation on time. Many clients entrust us with managing their annual shutdowns of mission critical facilities.

Warehousing & Materials Management Services We have become accustomed to managing the warehousing and materials management aspect of our projects. Many clients rely on our expertise to receive all owner furnished material and equipment, coordinate all necessary inspections and ensure all parts are available for installation when required.

Validation / Commissioning During the course of project execution we develop a Start-Up & Commissioning Plan and a TOP Manual outline that will clearly identify the activities required to successfully commission and turn over a project. This early planning effort will assure a successful transition = % % E MEP Specialists, our extensive knowledge of the systems that we build, the quality with which we build them, and the complete understanding of how they are used during normal operations.


WE CAN HELP

SERVICES

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Preconstruction

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Constructability Review

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Value Planning

We are dedicated to Building Your Vision.

Long Lead Procurement Preliminary Budgets Bid Packages Construction Cost Estimate Schedule Development

Construction Submittal Expediting & Tracking Cost Control Procedures Schedule Control Document Control Quality Control Corrective Work List MEP Coordination Start-Up & Commissioning TOP Document Planning Equipment Purchasing & Tracking Warehousing / Materials Management $ < !

Sustainable Construction Dome Construction believes in helping to build a cleaner, more sustainable future. We proudly partner with our Clients, Designers and Consultants to help them determine and achieve sustainable goals for their projects. >

materials on the site, provide a healthier work environment, locate local products, manufacturers and vendors, or actually aiming for LEED LEED Accredited Professionals are here to help. Dome Construction fosters an environment that on the job site, within our communities and beyond.

Laboratories Research & Development BioFuel Facilitties cGMP Manufacturing Environmental Rooms Clean Rooms Cold Rooms Vivariu um s Central Plan ntss Pilot Plants Warehousing Joint BioEnergy Institute (JBEI)


clients Some of our recent clients include: Abgenix Corporation Allergan Alza Corporation Amgen Amyris Biotechnologies Applied Biosystems Aradigm Corporation Artemis

thorough

Aviron Corporation Baxtar Healthcare Bayer Healthcare Berlex Corporation BioMarin Pharmaceutical Bio Rad

trusted

Celgene Chiron Corporation Dey Laboratories Durect, Inc. Dynavax Laboratories

Genentech, Inc. Geron Corporation Gladstone Institutes Heraeus/Amersil HML Labs Hyseq, Inc.

dependable

Intarcia Therapeutics Intrabiotics Pharmaceuticals Joint BioEngergy Institute (JBEI) Johnson & Johnson KineMed Lawrence Livermore National Labs Lawrence Berkeley National Labs Life Technologies LS9 Nektar Therapeutics Novartis Vaccines & Diagnostics Occlassen Pharmaceutical Origen Therapeutics Ortho–McNeil PIC Group Laboratories

Headquarters

South Bay

Dome Construction Corporation 393 East Grand Avenue ! ! : 5 /KN2N X3N K+X 3XNN Z X3N K+X 3XN[ Z

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Sangamo Laboratories Stanford School of Medicine

www.domeconst.com

Stanford University University of California, Berkeley Wareham Development Xoma

8 printed on 100% recycled content.


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