Understanding Adrenal Fatigue Adrenal fatigue, medically known as hypoadrenia, is often controversial; there is the debate if adrenal fatigue is its own syndrome or a symptom of another medical condition like that of Addison’s disease. Either way, Adrenal fatigue can really affect one’s health negatively when it comes to weight loss attempts. To understand the effects adrenal fatigue has on weight loss, it’s important to understand what it is. Adrenal fatigue is associated with constant and overwhelming stress. Often people complain of being tired, feeling exhausted or run down and physically and emotionally stressed. In an attempt to address the problem, people will use excessive amounts of caffeine and sweets to keep their energy up. What happens to the body when it’s overly stressed is fairly simple to understand. When the body is experiencing high levels of stress it produces lesser amounts of cortisol, a hormone released by the adrenal gland. Although the adrenal gland produces other hormones such as estrogen, adrenalin, and androgen; cortisol is the primary hormone of the adrenal gland with the goal of responding to stress by increasing production. Cortisol converts’ protein into energy. Under normal circumstances when the body experiences stress or when there is a need for the “fight or flight” response, cortisol initially increases to the point of homeostasis and then decreases when the stress is relieved. However, if that stress is not relieved; cortisol continues to produce and the adrenal gland tires leading to adrenal fatigue, which in turn begins to fail in hormone production.