Junior Researchers Directory 2011

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Junior Researchers


The Junior researchers directory was produced by Future Faculty at Sahlgrenska Academy 2011. Production support: Information office at Sahlgrenska Academy (info@sahlgrenska.gu.se) Printed by Elanders Sverige AB, Gothenburg 2011


Junior researchers directory 2011


The Sahlgrenska Academy

The Sahlgrenska Academy is the faculty of health sciences at the University of Gothenburg, providing health sciences education for the professionals of the future. With key concepts such as a holistic approach, cooperation and excellence in knowledge-building, the faculty shall contribute towards advances within the prevention, alleviation and treatment of disease and ill-health. About 6500 students and 850 PhD students are enrolled at Sahlgrenska Academy. Approximately 1,600 people are employed. 860 of them are researchers and/or teachers. 2010 Sahlgrenska Academy had a turn­ over of almost 2,100 million SEK. Both education and research is conducted in close cooperation with the Västra Götaland region, particularly the Sahlgrenska University Hospital.


Junior researcher directory In this directory you will find individual profiles of creative and ambitious young researchers at Sahlgrenska Academy 2011. All scientist presented here hold a PhD, or are less than one year from defending a doctoral thesis. Besides unique competences and expertise in specific research fields, researchers have many skills and competences that are of value for diverse sectors of the professional society. ~~ ~~ ~~ ~~ ~~ ~~ ~~

Project management Presentation and communication skills A trained ability to take in new subjects, methods and techniques Administrative and coordinating skills Goal oriented way of working Analytic and problem solving abilities Processing and summarizing information


Future Faculty board members, from top left; Britt-Marie Iresjö, Karin Welén, Sara Lindén, Petronella Kettunen, Sandra Olsson, Annika Gustafsson Asting, Lars Westberg, Charlotta Olofsson, Lena Larsson. Missing: Karolina Partheen, Christin Karlsson, Silvia Gogg, Annika Bergman, Katarina Ejeskär, Mia Ericson, Åsa Sjöling, Björn Lindkvist, Iris van Dijk Härd, Erik Pålsson


Future Faculty at Sahlgrenska Academy Future Faculty is an organization at Sahlgrenska Academy for those in the middle of their career. Our members have a PhD degree and are actively involved in research but do not have a permanent position as lecturer or professor. To support junior scientists, Future Faculty acts as a network to facilitate collaboration among junior scientists. Future Faculty also organizes member meetings on relevant subjects for the junior researcher (from scientific to political) and interacts with the Academy concerning topics of interest to junior scientists. Future Faculty wishes to inspire and encourage the Academy to support and maintain the competence of junior scientists in their strategic plan for excellence in both research and teaching. Future Faculty is run by a board which represents each institute at the Sahlgrenska Academy. Co-chairs are Sandra Olsson and Erik P책lsson. We can be reached at futurefaculty@sahlgrenska.gu.se. For more information see www.sahlgrenska.gu.se/forskning/future_faculty.


MEMBERS Louise Adermark ������������������������������������������ Camilla Alexanderson ��������������������������������������� Elin Andersson ������������������������������������������� Mattias Andersson ����������������������������������������� Michael Andersson ���������������������������������������� Gabriella Arne ������������������������������������������� Julia Asp ���������������������������������������������� Malin Bäckström ������������������������������������������ Marcela Davila ������������������������������������������� Mate Erdelyi �������������������������������������������� André Fehr ��������������������������������������������� Louise Grahnemo ����������������������������������������� Anna Grimby-Ekman ��������������������������������������� Ola Grimsholm ������������������������������������������� Annika Gustafsson Asting ������������������������������������ Nina Hellström Erkenstam ������������������������������������ Michael Hoppe ������������������������������������������� Anna-Karin Hultgård Ekwall ����������������������������������� Helga Höifödt Lidö ���������������������������������������� Britt-Marie Iresjö ������������������������������������������ Elisabet Jerlhag ������������������������������������������ Inger Johansson ������������������������������������������ Christin Karlsson ������������������������������������������ Gergely Katona ������������������������������������������ Petronella Kettunen ���������������������������������������� Lena Larsson ��������������������������������������������

6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31


Sara Lindén ��������������������������������������������� Elin Löf ����������������������������������������������� Jesper Löve ��������������������������������������������� Junmei Miao Jonasson �������������������������������������� Peter Molnár �������������������������������������������� Matilda Nicklasson ���������������������������������������� Peter Norberg ������������������������������������������� Ann Novotny �������������������������������������������� Hanna Olausson ������������������������������������������ Sandra Olsson ������������������������������������������� Fredrik Persson ������������������������������������������� Christopher Pickering ��������������������������������������� Erik Pålsson ��������������������������������������������� Madeleine Rådinger ���������������������������������������� Justin F. Schneiderman �������������������������������������� Linnea Stridh �������������������������������������������� Petra Suchankova Karlsson ������������������������������������ Helena Svensson ������������������������������������������ Jonas Söderholm ����������������������������������������� Fabian Taube �������������������������������������������� Magdalena Taube ����������������������������������������� Anna Tjärnlund Wolf ���������������������������������������� Karin Welén ��������������������������������������������� Sara Windahl �������������������������������������������� Ulf Yrlid �����������������������������������������������

32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56


LOUISE ADERMARK Title: PhD Languages: Swedish, English Contact: louise.adermark@neuro.gu.se | +46 (0)317863975

Thesis/Thesis Project

Ethanol-mediated effects on astroglial cells in primary culture - with a focus on acute changes in intracellular Ca2+, cell volume, actin filaments, and gap junction coupling, Sahlgrenska Academy, 2003

Teaching

Cell biology, neuroanatomy and physiology, pharmacology

Competence in brief

Electrophysiology, primary cell-cultures, imaging techniques, immunohistochemsitry, brain dissection, brain slice preparation Louise has a background in environmental science and chemistry and conducted her PhD studying alcohol effects on glial cells. Following dissertation she spent 2.5 years at the National Institute of Alcohol Abuse and Alcoholism (USA), using electrophysiology to explore mechanisms associated with learning and memory and to continue her thesis studies. Louise currently works at the Addiction Biology Unit and holds a research position financed by the Swedish Research Council. –6–


CAMILLA ALEXANDERSON Title: PhD Languages: Swedish, English Contact: camilla.alexanderson@wlab.gu.se | +46 (0)736952478

Thesis/Thesis Project

Metabolic and ovarian consequences of perinatal sex steroid programming, Sahlgrenska Academy, 2008

Teaching

Pharmacy programme, dentist programme, dietitian programme, lab supervision, lectures

Competence in brief

Euglycemic hyperinsulinemic clamp, computerized determination of adipocyte size , methods for estimation of body composition, vaginal smears, realtime-RT-PCR, en face preparation of aortas, histochemical and immunohistochemical stainings for analysis of aorta, analytical methods Attended Gothenburg Gradauate School of Biomedicine before starting as a PhD student. Currently she holds a postdoc position in Åsa Tivesten´s group at the Wallenberg laboratory. Her work examines the role of the androgen receptor in the development of abdominal aortic aneurysms. Camilla´s main personal qualifactions are ambitious, organized and focused. She is a verbal and communicative person who find teaching and supervising stimulating. She enjoy challenges and to reflect and troubleshoot. –7–


ELIN ANDERSSON Title: PhD Languages: Swedish, English Contact: elin.andersson@microbio.gu.se | +46 (0)733940160

Thesis/Thesis Project

Short modified peptides and their metabolites inhibit HIV replication, Sahlgrenska Academy, 2005

Teaching

Basic virology, antivirals, viral genetics, tumor virology

Competence in brief

Primary cell culture, in vitro assays on antiviral efficacy and drug resistance, ELISA, DNA and RNA extraction, sequencing, fragment analysis, RT-PCR Elin has a MSc in Pharmaceutical bioscience, and a PhD in Clinical virology. Her PhD project concerned development of antiviral drugs, with focus on HIV and drug resistance, in collaboration with Tripep AB. She is currently working at the Dept of Clinical virology in a project on human papillomavirus and cervical cancer. Her main interests are in development of viral diagnostics and biomarkers for cancer progression. She is also pursuing studies for a medical doctor degree at the university.

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MATTIAS ANDERSSON Title: PhD Languages: Swedish, English Contact: mattias.andersson@llcr.med.gu.se |

Thesis/Thesis Project

FET proteins in cancer and development, Sahlgrenska Academy, 2009

Teaching

Cell biology, tumor biology

Competence in brief

Human primary cell culture, cell based assays, growth factor signaling, cDNA cloning and expression, transfection, RNA interference, quantitative real-time PCR, immunoprecipitation, Western blot, confocal microscopy, immunofluorescence Mattias' main research interests are functional studies of fusion oncogenes in solid tumors. Mattias holds a MSc in Chemistry and has a background in biochemistry and molecular biology at University of Gothenburg. He attended the Göteborg Graduate School of Bioscience and was thereafter enrolled as a PhD student at the Dept of Pathology with professor Pierre Åman. Mattias currently works as a postdoc in professor Göran Stenman's group at Sahlgrenska Cancer Center. –9–


MICHAEL ANDERSSON Title: PhD Languages: Swedish, English, French Contact: michael.andersson@pharm.gu.se | +46 (0)317863440

Thesis/Thesis Project

Muscarinic Receptors in the Urinary Bladder - The role of the urothelium regarding cholinergic and nitrergic effects in inflammation, Sahlgrenska Academy, 2010

Teaching

Course leader for two courses and teacher at eight different programs at the Sahlgrenska Academy

Competence in brief

Pharmacology, autonomic neuroscience, lower urinary tract, inflammation, cholinergic receptors, purinergic receptors, incontinence, cystitis, bladder cancer, micturition, nitric oxide, in vivo surgery, organ bath, metabolism cage, cell culturing, proliferation, immunohistochemistry, Western blot Post doctoral projects include in vivo measurements of nitric oxide, studies of the development of inflammation, in vitro receptor characterization and cell proliferation studies. Awarded degree of PhD in Medicine, 2010 and degree of Master in Medicine, 2005. Master thesis project - Mitochondrial trafficking in primary cortical neurons, University of Pittsburgh, Pittsburgh, USA – 10 –


GABRIELLA ARNE Title: PhD Student Languages: Swedish, English Contact: gabriella.arne@gu.se | +46 (0)736109294

Thesis/Thesis Project

Expression profiling of gastrointestinal stromal tumors (GISTs) – new biomarkers for prognosis and therapy, Sahlgrenska Academy, 2012

Competence in brief

Gene expression analysis with microarray and qPCR techniques, primary tumor cell culturing, immunohistochemical and immunocytochemical techniques, survival analysis, vector cloning, heterologous protein expression in yeast, and optimization of yeast growth in bioreactor Gabriella has a MSc in Engineering biology, with the alignment of molecular biotechnology, from Linköping Institute of Technology. Prior to the current PhD student position, she attended Gothenburg Graduate School in Bioscience at the University of Gothenburg.

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JULIA ASP Title: PhD Languages: Swedish, English Contact: julia.asp@gu.se | +46 (0)702998316

Thesis/Thesis Project

Cell cycle genes in chondrosarcoma. Involvement of the Id1 and p16 pathways, Sahlgrenska Academy, 2002

Teaching

Since 2009, teaching at the programme in biomedical laboratory science, University of Gothenburg

Competence in brief

Adult stem cells, tumour biology, heart, cartilage, primary cell culture, methods in molecular biology including real-time PCR Julia has performed two postdoc periods and since 2006, she is the project leader for a heart research team which works with projects concerning adult stem cells and regenerative medicine, cell signalling pathways and toxicology within the human adult heart. During 2007-2009, she was responsible partner deputy for the EU STREP project Invitroheart.

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MALIN BÄCKSTRÖM Title: PhD Languages: Swedish, English Contact: malin.backstrom@medkem.gu.se | +46 (0)708993496

Thesis/Thesis Project

Genetically modified cholera toxin B-subunit, Sahlgrenska Academy, 1997

Teaching

Cell biology, biochemistry and recombinant proteins, on both advanced and research level

Competence in brief

Molecular biology and protein biochemistry methods, production and design of recombinant proteins for production in mammalian cells, structural characterization of carbohydrates on glycoproteins using mass spectrometry Malin has a long experience working with proteins, especially recombinant proteins, earlier in procaryotes but later mainly in mammalian cells. She started with the expression and characterization of glycoproteins during her second postdoc at the Sahlgrenska Academy. Her first postdoc was at the University of Cambridge. Since 2004, she is running the core facility Mammalian Protein Expression, which she combines with research about glycoproteins and glycans at the Dept of Biomedicine. – 13 –


MARCELA DAVILA Title: PhD Languages: Swedish, English, Spanish Contact: marcela.davila@medkem.gu.se | +46 (0)763279100

Thesis/Thesis Project

Bioinformatics approaches to examine the evolution of proteins and ncRNAs, Sahlgrenska Academy, 2011

Teaching

Introduction to bioinformatics, sequence analysis

Competence in brief

Expertise in many of the basic methods of sequence analysis including genome annotation and phylogenetic analysis, skillful with processing large sets of data as well as in the UNIX operating system and Perl programming, experienced in managing and analyzing genome sequencing data Marcela has a basic education in molecular biology. During her PhD she became experienced in bioinformatics and her main research area was the identification and analysis of proteins and non-coding RNAs as well as the analysis of non-random gene order and its implications in translational regulation. Currently she is involved in the development of a bioinformatics platform for the analysis of exome sequencing data at the Inst of Biomedicine, Sahlgrenska Academy. – 14 –


MATE ERDELYI Title: Associate Professor Languages: Swedish, English, German, Hungarian Contact: mate@chem.gu.se | +46 (0)317869033

Thesis/Thesis Project

Towards the development of photoswitchable beta-hairpin mimetics, Uppsala University, 2004

Teaching

Medicinal chemistry, organic chemistry, NMR spectroscopy, advanced organic synthesis

Competence in brief

NMR spectroscopy - small molecules, natural products, ligand-protein interactions, conformational and configurational analysis, solution and solid-phase organic synthesis, SPPS, microwave chemistry, photochemistry, halogen bonding, hydrogen bonding, weak secondary interactions, Malaria Mate has his background in pharmaceutical sciences (MSc 1999), did his PhD in Organic/Medicinal chemistry (Uppsala University, 2004) followed by postdoctoral stays within physical organic chemistry (UCSD, 20042005), NMR method development and structural biology (Max Planck Institute, 2005-2008). He holds an associated professor position funded by Swedish Research Council and his work focuses on weak chemical interactions and on antiplasmodial natural products. http://halogenbond.weebly.com – 15 –


ANDRÉ FEHR Title: PhD Languages: English German Contact: andre.fehr@gu.se | + 46 (0)317866735

Thesis/Thesis Project

Genetic Analyses of Salivary Gland Tumors, University of Bremen, Germany, 2009

Competence in brief

Cancer research, cancer genetics, head and neck neoplasm, breast tumors, biomarker, diagnostic, prognostic, cancer treatment, molecular biology, microbiology, cell culture, formalin fixed, paraffin embedded material, array CGH André has a background in human- and cancer genetics. His research is focused on identification of new biomarkers for diagnosis, prognosis and treatment of cancer. He is specialized in molecular work with formalin fixed, paraffin embedded tissues. André is a postdoctoral research fellow in the group of professor Göran Stenman at Sahlgrenska Cancer Center.

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LOUISE GRAHNEMO Title: PhD Languages: Swedish, English, German Contact: louise@grahnemo.se | +46 (0)739946505

Thesis/Thesis Project

Interactions between Nutrition, Obesity and the Immune System, Sahlgrenska Academy, 2009

Teaching

Metabolism, obesity, sepsis

Competence in brief

RT-PCR including TLDA cards, bacterial load measurements, statistical analysis, genetic association studies. In mice: body composition measurements by DXA, injections (iv, ip, and sc), sepsis model, different dietary regiments, and dissection of various organs. Louise works at Dept of Physiology, Sahlgrenska Academy continuing her PhD project but have also worked with atherosclerosis and natural antibodies. Louise is thorough and eager to learn new techniques. In her spare times she enjoys travelling and playing basketball.

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ANNA GRIMBY-EKMAN Title: PhD Languages: Swedish, English Contact: anna.ekman@amm.gu.se | +46 (0)317863123

Thesis/Thesis Project

Epidemiological aspects of musculoskeletal pain in the upper body. Analyzing common and recurrent binary outcomes, Sahlgrenska Academy, 2010

Teaching

Teaching biostatistics for health scientist researchers since 1996

Competence in brief

Statistics and epidemiology, with special interest in the analysis of ordinal data and the use of logistic regression for repeated measurements, and in development of questionnaire based intruments using RASCH-analyses, pain epidemiology, pain measurements and risk factors for musculoskeletal pain Anna spent two semesters of her PhD studies at the Dept of Mathematical Statistics at University of Wisconsin-Madison 1992, included in the thesis in statistics defended in1997. In 2010 the thesis at the Medical Faculty was defended, Anna Ekman is now, as a project leader for a project on pain and work ability, collaborating with Björn Gerdle and Britt Larsson at the Health University at Linköping. – 18 –


OLA GRIMSHOLM Title: PhD Languages: Swedish, English, French, Hungarian Contact: ola.grimsholm@rheuma.gu.se | +46 (0)733142252

Thesis/Thesis Project

Neuropeptides and neurotrophins in arthritis - Studies on the human and mouse knee joint, Umeå University, 2008

Teaching

Anatomy, immunology, basic laboratory techniques

Competence in brief

Autoimmune diseases, immunology, peripheral nervous system, immunohistochemistry, flow cytometry, working with animal models of autoimmune diseases Main focus is on autoimmunity and how B cells play a role in autoimmune diseases. His thesis work showed how the peripheral nervous system is implicated in arthritis. The current project is focused on the pre-B cell receptor and how it is implicated in systemic autoimmunity. Personal fundings from Svenska Läkarsällskapet, Lundgrenska stiftelserna, Kungliga Vetenskaps och Vitterhets-samhället i Göteborg, Amlövs stiftelse.

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ANNIKA GUSTAFSSON ASTING Title: PhD Languages: Swedish, English Contact: annika.gustafsson@surgery.gu.se | +46 (0)739780160

Thesis/Thesis Project

Prostanoids and Colorectal Cancer, Sahlgrenska Academy, 2010

Teaching

Tumor biology, molecular biology techniques, RNA handling

Competence in brief

Gene expression assays, quantitative PCR, CGH microarrays, analyzing programs such as genomic workbench and genespring, RNA and DNA isolation from solid tumors and cells, cell cultures, siRNA, epigenetic analysis, ELISA, statistical analysis, inflammation, cancer Annika has focused her research on inflammation and cancer. She has a background in biomedical chemistry and during her PhD she performed gene expression analysis in human colorectal cancer. She has experiences from several different molecular biology techniques and has good organising and planning skills. Annika is currently a postdoc at the Dept of Surgery, Sahlgrenska Academy.

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NINA HELLSTRÖM ERKENSTAM Title: PhD Languages: Swedish, English Contact: nina.erkenstam@neuro.gu.se | +46 (0)704279427

Thesis/Thesis Project

Regional differences in the response of neural stem cells and their microenvironment to ionizing radiation, Sahlgrenska Academy, 2009

Competence in brief

Photothrombotic stroke model, intraperitoneal injections, transcardial perfusion, brain dissection, primary cell-culture preparation, adult neural stem cell cultures, human embryonic stem cell cultures, immunohistochemical techniques, stereological microscopy, confocal microscopy, FACS, qPCR Nina has an extensive background within the field of adult neural stem cells. Prior to her graduate studies, she worked four years in a biotech company. Nina holds a PhD in Neurobiology. During her thesis project, she studied the acute and chronic effects of ionizing radiation to the young brain. Nina currently holds a postdoc position financed by Vinnova, investigating novel biomaterials for culturing human embryonic stem cells.

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MICHAEL HOPPE Title: PhD Languages: Swedish, English Contact: michael.hoppe@nutrition.gu.se | +46 (0)317863705

Thesis/Thesis Project

Iron Absorption in Man - Diet Modification and Fortification, Sahlgrenska Academy, 2008

Teaching

Teaching nutrition. Supervising undergraduate students

Competence in brief

Coordinating human studies, both independently, within smaller teams, and in larger international cooperation, communicator at international congresses, peer-reviewer for several journals, main research area is human iron metabolism in different populations and conditions, especially inflammation Currently holds a position as research assistant at the Sahlgrenska University hospital. Main tasks, besides the clinic, include planning, coordinating, documentation and evaluation of clinical studies. Current research includes both exploratory and confirmatory studies in pregnancy, heart surgery, and also healthy subjects. He is a reliable, ambitious and helpful person with a high degree of scientific integrity and a skeptical attitude, as well as practical-minded and with a cheerful temperament. – 22 –


ANNA-KARIN HULTGÅRD EKWALL Title: PhD Languages: Swedish, English, German Contact: anna-karin.hultgard.ekwall@rheuma.gu.se | +46 (0)313424056

Thesis/Thesis Project

Fibroblast contractility in vivo and in vitro. Effects of prostaglandins and potential role for inner ear fluid homeostasis, Uppsala University, 2006

Teaching

Rheumatic diseases/rheumatoid arthritis, immunopathology/autoantibodies, immunohistochemistry

Competence in brief

Rheumatology, rheumatoid arthritis, synovial fibroblasts, biobanking, primary cell culturing, cryosectioning, immunohistochemistry, confocal immunofluorescence, flow cytometry, RNA interference, basic biochemistry and molecular biology techniques Anna-Karin has a MSc in Cell and Molecular Biology and a University Medical Degree at Uppsala University. During her PhD studies, she spent six months at Innsbruck Medical University in Austria learning immunohistochemistry. Anna-Karin is currently working as a resident at the Rheumatology Clinic, The Sahlgrenska University Hospital, and as a postdoc at Dept of Rheumatology and Inflammation Research, Sahlgrenska Academy. Anna-Karin is chairman of Future Faculty Rheumatology. – 23 –


HELGA HÖIFÖDT LIDÖ Title: PhD Languages: Swedish, English, Norwegian Contact: helga.lido@neuro.gu.se | +46 (0)709179311

Thesis/Thesis Project

Preclinical investigations of GlyT-1 inhibition as a new concept for treatment of alcohol dependence, Sahlgrenska Academy, 2011

Competence in brief

Neuropharmacological preclinical research and drug investigations, biological addiction research, with special training in behavioral animal studies and in vivo microdialysis techniques, collaborated with pharmaceutical industry. Authorized pharmacist, degree from University of Tromsö in Norway. A master of neuropharmacology, earnad at the Medical College of Georgia, Alzheimer’s Research Center, USA, 2001. She has held a position at Frogner Pharmacy in Oslo 2001-2004, in charge of drug information to users. From 2004 she works at University of Gothenburg.

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BRITT-MARIE IRESJÖ Title: PhD Languages: Swedish, English Contact: britt-marie.iresjo@gu.se | +46 (0)3423678

Thesis/Thesis Project

Initiation of protein biosynthesis in skeletal muscles at feeding, Sahlgrenska Academy, 2010

Competence in brief

Protein synthesis estimations, protein separation and detection, RNA preparation, real-time PCR and microarray analysis, cell culturing, rodent tumor models Britt-Marie is currently employed at the Dept of Surgery where she is part of a research group focusing on mechanisms behind the cancer cachexia/anorexia syndrome. Her research is mainly focused on translational control and intracellular signalling in relation to activation of protein synthesis in muscle tissue after nutrient intake.

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ELISABET JERLHAG Title: Associate Professor Languages: Swedish, English, German Contact: elisabet.jerlhag@pharm.gu.se | +46 (0)317863418

Thesis/Thesis Project

The Cholinergic-Dopaminergic Reward Link and Addictive Behaviours - special emphasis on ethanol and ghrelin, Sahlgrenska Academy, 2007

Teaching

Lecturer and supervisor of bachelor and master thesis

Competence in brief

Stereotaxic surgery, in vivo microdialysis in discreet brain areas, HPLC-EC method, consumption experiments, brain dissections, blood sampling, locomotor activity, conditioned place preference, operant self-administration, peptide synthesis, RIA analysis, cell culture experiments, DNA expression Elisabet, a junior researcher supported by Swedish Research Council, has conducted postdocs at the Dept of Pharmacology, Physiology as well as Clinical Chemistry, University of Gothenburg, and also at Ernst Gallio Institute, University of California, San Francisco, USA. The aim of her translational project is, by using a combination of behavioural, pharmacological, biochemical and genetic methods, to gain insight into the neuronal mechanisms underlying the dependence producing properties of alcohol. – 26 –


INGER JOHANSSON Title: PhD Languages: Swedish, English Contact: inger.johansson@clinchem.gu.se | +46 (0)709205821

Thesis/Thesis Project

Proliferative and protective effects of the GH/IGF-I axis on cardiomyocytes and neural progenitor cells, Sahlgrenska Academy, 2008

Teaching

Scientific methods and management, biochemistry, clinical chemistry and haematology

Competence in brief

Cell culturing, immuno precipitation, Western blot, 2D-electrophoresis, immunohistochemistry, conventional and confocal microscopy, 3H-thymidine incorporation, receptor binding, real time RT-PCR, flow cytometry (scanning and sorting), ELISA, raising monoclonal antibodies in rats Inger has a long background as a biomedical scientist and before her dissertation she worked two years at the European Molcular Biology Laboratory (EMBL) in Heidelberg, Germany. She has also been working in clinical chemistry laboratories both in Sweden, in Saudi Arabia and for the UN in Lebanon. She now works at the Inst of Biomedicine at the Sahlgrenska Academy and her project is on alpha-dystroglycan and its role in normal and diseased nervous system. – 27 –


CHRISTIN KARLSSON Title: Phd Languages: Swedish, English, German Contact: christin.karlsson@gu.se | +46 (0)706625212

Thesis/Thesis Project

Effects of surface adsorbed plasma proteins, protein-cell and cell-cell interactions at biomaterial surfaces. , Sahlgrenska Academy, 1997

Teaching

Biomedicine, medical genetics, tumour biology and metastasis, molecular biology, biochemistry, biology, histopathology, cell culturing

Competence in brief

Medical genetics, conventional and conditional gene-targeting, gene-trapping, transgenic approaches using mice models, histopathology, cell culturing, biomedicine, tumour biology, molecular biology, histopathology, and biochemistry Christin has a background in histopathology and has mainly focused on the posttranslational processing of CAAX proteins using an array of molecular biology and genetics techniques. CAAX proteins are important for many diseases in humans, mutations in genes that encode CAAX proteins contribute to the development of cancer. Her primary goal of research is to find new strategies for cancer and leukemia treatment. – 28 –


GERGELY KATONA Title: Associate Professor Languages: Swedish, English, French, German, Hungarian Contact: gergely.katona@chem.gu.se | +46 (0)707167586

Thesis/Thesis Project

Intermediate State Stabilisation in Enzyme Catalysis, Chalmers University of Technology, 2004

Teaching

X-ray crystallography, biochemistry

Competence in brief

X-ray crystallography, kinetic crystallography, ultrafast X-ray scattering techniques, membrane protein crystallization, Raman spectroscopy, proteases, photosynthesis, metalloproteins, enzymology Gergely studied biology at the Eötvös Loránd University, his main research topic is studying the dynamics of protein action. After his PhD he worked at the European Synchrotron Radiation Facility. There he studied catalytic intermediates of superoxide reductase. For his work he was awarded a medal from the French Academy of Science in 2008 and the Young Scientist Award from the ESRF in 2009. He is now a Senior Researcher of the Swedish Research Council in advanced scattering techniques.

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PETRONELLA KETTUNEN Title: PhD Languages: Swedish, English, French, German Contact: petronella.kettunen@neuro.gu.se |

Thesis/Thesis Project

Neuromodulation within a spinal locomotor network - role of metabotropic glutamate receptor subtypes, Karolinska Institutet, 2004

Teaching

Experience from 12 years of teaching in neurobiology, physiology and imaging

Competence in brief

Learning and memory, motor control, neuromodulation, electrophysiology, calcium imaging, confocal/2photon imaging, cell culture, molecular biology, behavior, zebrafish techniques Petronella did her graduate work in the field of motor control and neuromodulation. She then spent over three years at University of California, Los Angeles, where she developed a new zebrafish model of learning and memory that allows for transgenic manipulations, behavioral testing and in vivo calcium imaging. She has received individual funding during the last six years, including a major EU grant starting summer 2011. Other strengths include scientific/popular writing and lecturing. – 30 –


LENA LARSSON Title: PhD Languages: Swedish, English Contact: lena.larsson@odontologi.gu.se | +46 (0)317863178

Thesis/Thesis Project

Functional analysis of the -1087 single nucleotide polymorphism in the IL-10 promoter region, Sahlgrenska Academy, 2010

Competence in brief

Cell culture preparations, histological techniques such as IHC, ISH and in situ PLA, RNAi, transfection methods, ChIP, EMSA, ELISA, preparation of RNA and DNA, real-time PCR analysis and epigenetic analysis of DNA methylation and histone modifications Lena was awarded the ”Best thesis in 2010” from the Inst of Odontology. Her research focus is on mechanisms involved in the regulation of chronic inflammation, with a main interest in genetic and epigenetic regulation of gene expression. She currently holds a research position at the Dept of Periodontology, Inst of Odontology and is at present a member of the Future Faculty board.

– 31 –


SARA LINDÉN Title: Associate Professor Languages: Swedish, English Contact: sara.linden@gu.se | +46 (0)317863058

Thesis/Thesis Project

Helicobacter pylori binding to gastric mucins and host glycosylation changes after inoculation, Lund University, 2004

Teaching

Cell biology and tissue engineering

Competence in brief

Model development, arteficial mucosal surfaces, in vitro and in vivo infection studies with gastrointestinal pathogens; main pathogen system of interest: Helicobater pylori, Campylobacter jejuni, enteropathogenic and enterohaemorrhagic E. coli infection. Sara is the team leader of the “Mucins in Infection and Cancer” group, including two PhD students, two post docs and one technician. The group investigate the role of mucins during host defense against bacteria as well as the function of changes in mucosal mucin expression and glycosylation associated with disease. Sara has previously performed research at Lund University, Mater Medical Research Institute (Australia), USUHS (USA) and NASA (USA). – 32 –


ELIN LÖF Title: PhD Languages: Swedish, English Contact: elin.lof@neuro.gu.se | +46 (0)731502717

Thesis/Thesis Project

Conditional and non-conditional reward-related responses to alcohol - nicotinic mechanisms, Sahlgrenska Academy, 2006

Teaching

Pharmacology, psychiatry, translational research methodology and clinical trials methods

Competence in brief

Clinical trials: design, planning, trial execution, quality assurance, data management, medical writing, general trial management, repsonsible person for pharmacovigilance Pre-clinical (rodents): microdialysis, conditioned reinforcement, other behavioral models in addiction, cognition/memory, PCR Elin did her PhD in in vivo pharmacology at the University of Gothenburg and partly at Yale University, USA. Her main current research area is translational addiction medicine where she performs most work tasks involved in investigator initiated clinical trials (phase IIb/IIIb) at the Addiction Biology Unit at Beroende­kliniken. She is also responsible person for pharmacovigilance and a medical student at the University of Gothenburg. – 33 –


JESPER LÖVE Title: PhD Languages: Swedish, English Contact: jesper.love@socmed.gu.se |

Thesis/Thesis Project

Contemporary aspects of health and performance among young adult women and men in Sweden, Sahlgrenska Academy, 2010

Teaching

Gender, work and health measuring well-being stress and performance among young working women

Competence in brief

Educational background: organizational and occupational psychology with a main focus on psychosocial conditions at work, stress theory, gender theory and its application withing health research, work with both quantitative and qualitative (grounded theory) methodology, analyse statistics with SAS Jespers current research focus is the association between gendered structures and inequalities in health between women and men; explaining the social gradient in sickness absence; the long-term effect on marginalization and sickness absnence of depression and anxiety in younger years; and individualization, work, and health – 34 –


JUNMEI MIAO JONASSON Title: PhD Languages: Swedish, English, Chinese Contact: junmei.miao.jonasson@gmail.com | +46 (0)739053278

Thesis/Thesis Project

Epidemiological studies on complications in type 1 diabetes, Karolinska Institutet, 2008

Teaching

Epidemiology from basic level to advanced level, biostatistics, statistical inferences

Competence in brief

Study design, statistical analysis, results interpretation, writing manuscripts of epidemiological studies on different diseases, teaching epidemiological theories and methods to all kinds of audience Junmei is an epidemiologist and researcher. Experienced in lecturing on epidemiology and biostatistics to all kinds of audience, such as medical students, postgraduate students to specialist doctors. She recieved funding from VINNOVA, Storstockholms Diabetesförening, AGfond, Stifteslen för Konrad och Helfrid Johanssons fond, Diabetesförbudent, etc. She has broad research interest in epidemiological studies, especially studies based on Swedish registers.

– 35 –


PETER MOLNÁR Title: PhD Languages: Swedish, English, German Contact: peter.molnar@amm.gu.se | +46 (0)317862857

Thesis/Thesis Project

Elemental compositio of fine particles: exposur in the general population and influence from different sources, Sahlgrenska Academy, 2007

Teaching

Lecturer in various courses and programmes on topics related to air pollution and exposure

Competence in brief

Aerosols, fine particles, coarse particles, PM2.5, PM10, elemental analysis, XRF, source apportionment, air mass trajectories, geographical information systems (GIS), wood smoke, traffic pollution Peter is working at occupational and environmental medicine att Sahlgrenska University Hospital as an environmental physicist. He has a broad knowledge of air pollution, its sources, how it is transported, and source apportionment.

– 36 –


MATILDA NICKLASSON Title: PhD Languages: Swedish, English, French, German, Arabic Contact: matilda.nicklasson@microbio.gu.se | +46 (0)317866204

Thesis/Thesis Project

Studies on the Expression and Regulation of Enterotoxins and Colonization Factors in Enterotoxigenic Escherichia coli (ETEC), Sahlgrenska Academy, 2008

Teaching

Laboratory courses for medical and pharmaceutical students, lecturing for pharmaceutical students

Competence in brief

Medical microbiology, molecular epidemiology, in vivo and in vitro virulence gene expression and regulation, antimicrobial resistance mechanisms, Enterotoxigenic Escherichia coli (ETEC), Acinetobacter baumannii, nosocomial E. coli and Klebsiella infections Matilda has a background in medical microbiology and global health, with experience from the WHO in Geneva. After her dissertation Matilda spent one year at a US government medical research facility in Cairo, Egypt, where she studied antimicrobial resistance in the Middle East. She currently holds a postdoc position financed by Sida, studying the molecular epidemiology and gene regulation of Enterotoxigenic Escherichia coli (ETEC). – 37 –


PETER NORBERG Title: PhD Languages: Swedish, English Contact: peter.norberg@gu.se | +46 (0)735 316166

Thesis/Thesis Project

Evolution of human alpha-herpes viruses , Sahlgrenska Academy, 2007

Teaching

Bioinformatics, cell biology, virology, computing science

Competence in brief

Bioinformatics: next generation sequencing, sequence analysis, viral and bacterial evolution, phylogeny and recombination analysis, programming, algorithmics, Molecular techniques: PCR, DNA sequencing, viral sample and cell culture preparation Peter is a bioinformatician. His main research area is the analysis of microbial evolution, and he has demonstrated that several different viruses speed up their evolution and adaptive capacity by homologous recombination. He has also shown that plasmids carrying antibiotic resistances adapt to, and travel between, widely differing bacterial species, which have far-reaching implications for the spread of antibiotic resistances. He currently holds a position in the Dept of Biomedicine, Sahlgrenska Academy. – 38 –


ANN NOVOTNY Title: PhD Languages: Swedish, English, German Contact: ann.novotny@surgery.gu.se |

Thesis/Thesis Project

Aspects of non-neuronal signalling functions of acetylcholine in colorectal cancer, University of Kalmar, 2009

Competence in brief

Immunohisto-and cytochemistry, Western blot, cell culturing, ELISA Ann has a background as MSc in Biotechnology. During her PhD she has focused on the non-neuronal signalling functions in colon cancer. Ann works currently in the Transplantation Biology, Dept of Surgery at the Sahlgrenska Academy, and focus on liver transplantation. Ann has experiences from several molecular biology techniques (IHC, ICC, Western blot, FACS sorting, ELISA), and has work with cell culturing more than five years. Ann is good in organizing.

– 39 –


HANNA OLAUSSON Title: PhD Languages: Swedish, English, German Contact: hanna.olausson@gu.se | +46 (0)317863789

Thesis/Thesis Project

Nutritional status in relation to the maternal insulin-like growth factor-system and health related variables in the off spring, Linköping University, 2004

Teaching

Nutrition, especially during pregnancy, lactation and childhood

Competence in brief

Nutrition, vitamin D, body composition, bone metabolism, the IGF-system, longitudinal studies in humans and rodents during pregnancy and lactation Hanna focuses on maternal nutrition during reproduction. After her PhD at Linköping University, she went for post doctorial training at Karolinska Institutet (8 months), and MRC Human Nutrition Research in Cambridge (2 years) studying changes in bone metabolism during pregnancy. In 2008, Hanna came to University of Gothenburg to set up a research group continuing to investigate maternal nutrition during reproduction. Hanna currently holds a research assistant position financed by FORMAS. – 40 –


SANDRA OLSSON Title: PhD Languages: Swedish, English, German Contact: sandra.olsson@neuro.gu.se | +46 (0)733601083

Thesis/Thesis Project

Signal transduction in macrophages. Intracellular pathways activated by microbial constituents, Lund University, 2006

Teaching

Cell biology, human genetics

Competence in brief

SNP/haplotype analyses, RNA/DNA extraction, molecular biology, statistical analysis, organizing of biological samples, cell culturing, animal studies, stroke, inflammation, cell signaling, Western blot, Northern blot, ELISA, IP, immunohistochemistry Sandra is a molecular biologist with a background in cell biology. Since 2008, she is conducting clinical research concerning the role of inflammation in stroke and outcome after stroke (functional outcome and cognition). Her main area at present is genetic association studies. She has good organizing and planning skills, and one of her favorite tasks is statistical analysis and data handling. Sandra had several commission of trust during her PhD, and is at present co-chair of Future Faculty. – 41 –


FREDRIK PERSSON Title: PhD Languages: Swedish, English Contact: fredrik.persson@gu.se |

Thesis/Thesis Project

Studies of Fusion Oncogenes and Genomic Imbalances in Human Tumors, Sahlgrenska Academy, 2007

Teaching

Medical oncology, pathology, anatomy, medical terminology

Competence in brief

Cancer genetics, fusion oncogenes, cell culture, cytogenetics, fluorescence in situ hybridization (FISH), spectral karyotyping (SKY), array comparative genomic hybridization (aCGH), immunohistochemistry Fredrik is an MD, PhD and currently holds a position as resident physician in Oncology at the Sahlgrenska University Hospital. After his dissertation in 2007 he has a post-doc position at the Sahlgrenska Cancer Center. Main research area is fusion oncogenes in solid tumors.

– 42 –


CHRISTOPHER PICKERING Title: PhD Languages: Swedish, English Contact: chris.pickering@neuro.gu.se | +46 (0)317863975

Thesis/Thesis Project

Factors affecting alcohol self-administration: learning, environmental and genetic influences on behaviour, Karolinska Institutet, 2006

Competence in brief

Behaviour (operant self-administration, memory testing, tests of exploration or anxiety-like behaviour) and neurochemistry analysis (in vivo microdialysis, qPCR, in situ hybridization, immunohistochemistry), medical writing, proofreading Chris has a pharmacology degree from McMaster University in Canada and a PhD from Karolinska Institutet. He spent two postdoc periods at Uppsala University acquiring skills in neurochemistry and also established/ customized the operant technique (Med Associates equipment). In 2008 he moved to the Sahlgrenska Academy to study how cognitive dysfunction affects the response to alcohol and whether treatment of this common symptom will improve the outcome for alcohol-dependent individuals. – 43 –


ERIK PÅLSSON Title: PhD Languages: Swedish, English Contact: erik.palsson@neuro.gu.se | +46 (0)709522875

Thesis/Thesis Project

Cognitive function studied in animal models of schizophrenia, Sahlgrenska Academy, 2006

Teaching

Lecturer in pharmacology for eight years and organizes a course in experimental animal models

Competence in brief

Competence in psychiatric disorders, pharmacology, toxicology and intellectual property strategies. Experience from both clinical and preclinical research. Laboratory skills in behavioral models, in vivo voltammetry and stereotaxic surgery. Experience in project management and professional writing. Erik has a background in pharmaceutical bioscience and his main research interest is in the role of cognitive function in psychiatric disorders. After finishing his thesis he visited the National University of Ireland Maynooth to work with the in vivo application of novel electrochemical microsensors. He is currently employed at the Sahlgrenska Academy and is working as a researcher in professor Mikael Landéns research group at the Dept of Psychiatry and Neurochemistry. – 44 –


MADELEINE RÅDINGER Title: PhD Languages: Swedish, English Contact: madeleine.radinger@gu.se | +46 (0)317866714

Thesis/Thesis Project

Local and systemic mechanisms of allergen-induced airway inflammation, Sahlgrenska Academy, 2006

Teaching

Cell biology, in vitro cell cultures and in vivo models of allergic inflammation (mouse)

Competence in brief

In vivo models of allergic inflammation (mouse) and in vitro cultures of primary cells and cell lines, microscopy (histological and immunohistological analysis), confocal microscopy, flow cytometric analysis, immunosorbent assays, Western blot analysis and PCR, shRNA technique Madeleines research area is mechanisms of allergic inflammation with special interest in eosinophil and mast cell effector functions and signaling pathways. She is working on translational asthma research and basic research using mouse models. After her dissertation she did a 2.5 year postdoc at the Laboratory of Allergic Diseases, National Institute of Health, Bethesda, USA, where she worked on projects involving mechanisms of receptor-mediated activation of human mast cells. – 45 –


JUSTIN F. SCHNEIDERMAN Title: PhD Languages: English Contact: justin.schneiderman@neuro.gu.se | +46 (0)761643201

Thesis/Thesis Project

Progress in measurement techniques for the single Cooper-pair box qubit, University of Southern California, 2007

Teaching

Cell biology, physiology, and general physics lab, and standard aptitude test

Competence in brief

Leadership, media-relations, and team-building training. Micro- and nano-fabrication High-Tc SQUIDs for biomedical applications: molecular diagnostics/immunoassays with magnetic nanoparticles (MNPs), magnetoencephalography (MEG) system, ultra-low field MRI system Justin came to the Chalmers University of Technology in Gothenburg to apply his technical background to the biomedical area. Participation in two EU framework programme projects and securing start-up funding from the Kristina Stenborgs stiftelse has helped him push devices towards the clinic. His position with MedTech West at Inst of Neuroscience and Physiology, the Sahlgrenska Academy, allows him to explore new ways of studying the brain with superconducting devices. – 46 –


LINNEA STRIDH Title: PhD Student Languages: Swedish, English Contact: linnea.stridh@neuro.gu.se | +46 (0)705764718

Thesis/Thesis Project

Inflammation and injury in the immature brain: The role of Toll like receptors, Sahlgrenska Academy, 2011

Teaching

Physiology

Competence in brief

Mouse model of hypoxia-ischemia in the immature brain, i.p and i.c.v injections, brain dissection, microvessel isolation, breeding of transgenic mice, immunohistochemical techniques, RT-qPCR Linnea has a MSc in Medical Biology from Linköping University and will defend her thesis in November 2011. During her undergraduate studies, Linnea got a scholarship for 8 months of research in the field of innate immunity. During her PhD studies, Linnea was also president for two years in one of Swedens biggest swing dance societies, West coast jitterbugs with over 600 members.

– 47 –


PETRA SUCHANKOVA KARLSSON Title: PhD Languages: Swedish, English, Czech Contact: petra.suchankova@pharm.gu.se | +46 (0)317863420

Thesis/Thesis Project

On the importance of inflammation for personality traits and psychiatric morbidity, Sahlgrenska Academy, 2011

Teaching

Pharmacology

Competence in brief

Human genetic association studies, gene-expression quantification, genotyping, gene-sequencing, epigenetics, forced swim test and dissection of the rat brain During her PhD, Petra studied the possible association between genes of the innate immune system and personality traits as well as psychiatric disorders. Her main area of research concerns genetics, especially association studies and molecular genetics. Petra is currently employed at the Dept of Pharmacology at the Sahlgrenska Academy where she is studying the relationship between the appetite stimulating peptide ghrelin and various aspects of substance dependence. – 48 –


HELENA SVENSSON Title: PhD Languages: Swedish, English Contact: helena.svensson@surgery.gu.se | +46 (0)702353091

Thesis/Thesis Project

Leukocyte recruitment to human gastrointestinal tissues -Studies in H. pylori-induced gastritis and colon adenocarcinomas, Sahlgrenska Academy, 2010

Teaching

Immunology, medical microbiology, supervision, lectures, laborations and group discussions

Competence in brief

Flow cytometry and cell sorting, isolation of lamina propria lymphocytes from solid tumors, immunohistochemical techniques, ELISA, Western blot, DNA- and RNA-isolation from cell lines and solid tumors, cell culture, real-time PCR, statistics Helena has a master degree in biology and after finishing her thesis at AstraZeneca she attended the Gothenburg Graduate School in Bioscience. Thereafter she was enrolled as a PhD student at the Dept of Microbiology and Immunology, studying the recruitment of immune cells to tumors and inflamed tissues in the gastrointestinal system. She currently holds a postdoc position at the Dept of Surgery at the Sahlgrenska University Hospital working with circulating tumor cells in pancreatic cancer patients. – 49 –


JONAS SÖDERHOLM Title: PhD Languages: Swedish, English Contact: jonas.soderholm@microbio.gu.se | +46 (0)732309278

Thesis/Thesis Project

The hepatitis C virus and immune escape, Karolinska Institutet, 2006

Teaching

Virology, immunology

Competence in brief

Animal handling (mostly mice), PCR, qPCR, Western Blot, ELISA, ELISpot, cell culturing, FACS, plasmid preparation, in vitro mutagenesis, cloning, sequencing His expertise lies within virology, immunology and vaccinology. Most of his research has focused on understanding the interactions between the immune system and the hepatitis C virus. During his postdoc in the USA he worked on developing a DNA vaccine against the Influenza A virus. Lately he has focused on understanding the role of NK-cells during viral infection. Furthermore, besides working fulltime Jonas also studied business administration and graduated recently with a Bachelor of Science.

– 50 –


FABIAN TAUBE Title: PhD Languages: Swedish, English, German Contact: fabian.taube@amm.gu.se | +46 (0)317866292

Thesis/Thesis Project

Characterization of Aqueous Peroxomolybdates with Catalytic applicability, Sahlgrenska Academy, 2003

Teaching

University: Inorganic solution chemistry, chemical health risks. High school: environmental science

Competence in brief

Potentiometry, FTIR, XAFS, ESEM, exposure assessments, chemical risk assessments, inorganic solution chemistry, solid state chemistry Fabian has a background in equilibrium chemistry. Research area is towards: 1) surface reactions at enamel apatite, 2) assessment of occupational exposure to chemicals/ particles. After dissertation he spent one year as research assistant and lecturer at Umeå University. He currently holds a combined research and clinical position at Sahlgrenska University Hospital. Fundings: 2002; Kempe foundation, 2007; Magnus Bergwall foundation (enamel surface), 2010 FAS (biomarkers of exhaled air)

– 51 –


MAGDALENA TAUBE Title: PhD Languages: Swedish, English Contact: magdalena.taube@wlab.gu.se | +46 (0)768444020

Thesis/Thesis Project

Ovarian tumours, cell isolation, cell survival and sex steroids, Umeå University, 2002

Teaching

Master of education for the upper secondary school (science/biology), Umeå University, 2000

Competence in brief

PCR, qPCR, cloning and transfection technologies, SNP analysis, LCM, cell culture, ELISA, IHC, electrophysiology, sequencing, stereotaxic surgery, cerebral injections, DXA and behavioural models Magdalena is experienced from the fields of obesity, neuroscience and cancer biology from the Universities of Umeå and Gothenburg, resulting in extensive scientific and laboratory knowledge in both in vitro and in vivo systems as well as handling of clinical biobank material. As a laboratory manager in professor Lena Carlson’s lab at the Wallenberg laboratory she enjoys to work in many projects and collaborations.

– 52 –


ANNA TJÄRNLUND WOLF Title: PhD Languages: Swedish, English, French Contact: anna.wolf@neuro.gu.se | +46 (0)706518416

Thesis/Thesis Project

On the tissue-type plasminogen (t-PA) -7,351C>T enhancer polymorphism, importance for endothelial t-PA gene expression and arterial thrombotic disease, Sahlgrenska Academy, 2004

Teaching

PhD and Master student supervision

Competence in brief

Cardiovascular disease/stroke, fibrinolysis, transcriptional regulation, genetics, pharmacology, neurobiology, isolation/culture of primary cells from brain and vasculature, DNA-protein interaction, cloning/transfection, SNP analysis, qPCR, microarray, immunohistochemistry, neurovascular plasticity Anna has a background in translational cardiovascular research. Her work, conducted at the Institute of Neuroscience and Physiology, at Monash University, Australia, and at Harvard Medical School, has focused on molecular genetic mechanisms in arterial thrombotic disease. With support from the Swedish Research Council, Anna is currently studying neurovascular dysfunction and neuroprotection in stroke. – 53 –


KARIN WELÉN Title: PhD Languages: Swedish, English Contact: karin.welen@urology.gu.se | +46 (0)706102231

Thesis/Thesis Project

Human ovarian surface epithelium and ovarian cancer, Sahlgrenska Academy, 2000

Teaching

Tumor biology, molecular biology, tumor metastasis, angiogenesis, steroids in cancer biology

Competence in brief

Gene expression, protein analysis, histology, cell culturing, epithelial cells, transfection, siRNA, animal models for cancer research, angiogenesis, hormone regulated cancer (prostate cancer, ovarian cancer) Karin has focused her research on cellular properties of epithelial cancer, involving induction of angiogenesis and metastasis, and regulation of proliferation and differentiation. Using in vitro and in vivo experimental models as well as clinical samples, her current research is aiming to identify new drug targets for castration resistant prostate cancer. The research is performed at the Dept of Urology, Inst of Clinical Sciences, as a part of Sahlgrenska Cancer Center.

– 54 –


SARA WINDAHL Title: PhD Languages: Swedish, English Contact: sara.windahl@gu.se | +46 (0)730804585

Thesis/Thesis Project

Functions of estrogen receptor beta in the metabolism of rodent, Karolinska Institutet, 2001

Teaching

Molecular biology and physiology

Competence in brief

In vivo and in vitro bone analysis including mechanical loading and hormone replacement studies, immunohistochemical techniques, histomorphometry, cell culture and gene transcription studies, She currently holds an assistant professor position financed by the Swedish Research Council. Sara has a background in cell- and molecular biology and her main research area is sex steroids and bone biology. After her dissertation at the Karolinska Institutet, she spent three years at Yale University School of Medicine, USA, where she used a mouse model and cell-cultures to study the mechanism of a new suggested candidate for treatment of osteoporosis. Her present research is focused around the mechanisms underlying the osteogenic effects of steroids and mechanical loading. – 55 –


ULF YRLID Title: Associate Professor Languages: Swedish, English, French Contact: ulf.yrlid@gu.se | +46 (0)317866225

Thesis/Thesis Project

Presentation of Salmonella Antigens by DCs, Lund University, 2001

Teaching

Extensive experience in immunology lectures for medical students and biology students

Competence in brief

Ten years of postdoctoral experience in mucosal and inflammation research, fifteen years experience of working in vivo with rodent models of immune pathology, extensive experience in supervising PhD students and post docs, excellent skills in immunological techniques Ulf is a Swedish Research Council funded associate professor. Heading a research group that performs in vivo experiments combining advanced surgical techniques and transgenic mice to determine how to induce appropriate immune responses following mucosal vaccinations and how to ameliorate inflammatory bowel diseases.

– 56 –



JUNIOR RESEARCHERS DIRECTORY In this directory you will find individual profiles of creative and ambitious young researchers at Sahlgrenska Academy 2011. All scientists presented here, hold a PhD, or are less than one year from defending a doctoral thesis. Besides unique competences and expertise in specific research fields, researchers have many skills and competences that are valuable for diverse sectors of the professional society.


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