Anti-Ebola Virus Antibody Products and Services USA
Europe
Tel: 1-631-381-2994
Tel: 44-207-097-1828
Fax: 1-631-207-8356
Email: info@creative-biolabs.com
Email: info@creative-biolabs.com
Heidenkampsweg 58, 20097
45-1 Ramsey Road, Shirley, NY 11967, USA
Hamburg, Germany
Contents
1
About Creative Biolabs
2
Ebola Virus Introduction
3
Ebola Virus Structure
4
Ebola Virus Antibody Products
5
Ebola Virus Antibody Development Services
6
Contact Us
About Creative Biolabs
Virology Antibody Expert Creative Biolabs is proud to be your trusted partner in advancing your virology breakthroughs, making your virology discoveries creative. We provide a comprehensive suite of primary antibody products against a wide range of viruses, secondary antibodies, isotype controls, pseudoviruses etc.
Quality Guaranteed Creative Biolabs has been setting the standard in quality virology research reagents for over 10 years. Our highly trained staff will strictly implement quality control procedures for antibody production. We adhere to the transparency of all quality data in every stage.
01
Anti-Ebola Virus Antibody Products and Services
Eloba Virus Introduction Ebola virus is an infectious agent and one of the viruses that can cause haemorraghic fever, a severe infectious disease characterized by high fever and bleeding, in humans and and non-human primates. The first infections with this viral genus were reported in Zaire, close to the river Ebola.
Fig.1 Taxonomy of the genus Ebolavirus (Shevin, Nature Rev, 2020).
02
Anti-Ebola Virus Antibody Products and Services
Fig.2 Ebola virus (TEM) (Shevin, Nature Rev, 2020).
Fig.3 Ebola virus transmission (Shevin, Nature Rev, 2020).
Structure of Ebola Virus
➢
Ebola virions have a complex construction and consist of an envelope, a nucleocapsid, a polymerase complex, and a matrix.
➢
Virions are enveloped, filamentous, or pleomorphic with
extensive branching or U-shaped or 6-shaped, about 80 nm in diameter, greatly variable up to 1400 nm long. ➢
Ebola virus (EBOV) has a linear, non-segmented, negative-sense,
Fig.4 Structure of a Eloba virion (Heinz, N Engl J Med, 2020).
single-stranded RNA genome (~19 kb) expressing seven structural proteins and several non-structural proteins from seven genes: NP encodes nucleoprotein NP, VP35 polymerase cofactor VP35, VP40 matrix protein VP40, GP glycoprotein GP1,2 and secreted glycoproteins, VP30 transcriptional activator VP30, VP24 RNA complex-associated protein VP24, and L large protein L. Fig.5 EBOV genome (Shevin, Nature Rev, 2020).
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Anti-Ebola Virus Antibody Products and Services
Ebola Virus Life Cycle The viral genome is encapsidated by NP and associated with L, VP35 and VP30 (forming the ribonucleoprotein (RNP) complex). Nucleocapsids are further associated with VP24, and they are surrounded by VP40. The glycoprotein GP1,2 is embedded in the host cell-derived envelope. Attachment of virions at the cell surface is followed by uptake via macropinocytosis into endolysosomes. Subsequently, the virus envelope fuses with the endolysosomal membrane and RNP complexes are released into the cytoplasm, where they relax and become transcriptionally active. Primary transcription is facilitated by viral RNP complex proteins brought into the cell, and viral mRNAs are translated into proteins by host ribosomes. The newly synthesized viral proteins facilitate secondary transcription and genome replication, copying the viral genomic RNA (vRNA) through an antigenomic intermediate (cRNA). Fig.6 EBOV life cycle (Hoenen, Nature Reviews Microbiology, 2019).
Newly formed RNP complexes condense into a packaging-competent form and are transported to budding sites, where morphogenesis and budding
04
Anti-Ebola Virus Antibody Products and Services
occurs in a process mediated by VP40.
Ebola Virus Antibody Products CAT#
Product Name
Host Species
Target
Application
VRX-0167Y
Mouse Anti-Ebola Virus VP24 Monoclonal Antibody (XY0026)
Mouse
VP24
ELISA, IHC-P, FCM, ICC, IF, IP
VRX-0169Y
Mouse Anti-Ebola Virus VP24 Monoclonal Antibody (XY0027)
Mouse
VP24
WB
VRX-0180Y
Rabbit Anti-Ebola Virus VP30 Polyclonal Antibody
Rabbit
VP30
WB, ICC, IF
VRX-0178Y
Mouse Anti-Ebola Virus VP35 Monoclonal Antibody (XY0034)
Mouse
VP35
WB, IP, IF
VRX-0125Y
Rabbit Anti-Ebola Virus VP40 Polyclonal Antibody
Rabbit
VP40
WB
VRX-0127Y
Mouse Anti-Ebola Virus VP40 Monoclonal Antibody (XY0016)
Mouse
VP40
ELISA, IHC-P, FCM, ICC, IF, IP
VRX-0157Y
Mouse Anti-Ebola Virus NP Monoclonal Antibody (XY0036)
Mouse
NP
WB, ELISA
VRX-0158Y
Mouse Anti-Ebola Virus NP Monoclonal Antibody (XY0018)
Mouse
NP
ELISA, IHC-P, FCM
VRX-0159Y
Mouse Anti-Ebola Virus NP Monoclonal Antibody (XY0019)
Mouse
NP
ELISA, IHC-P, FCM, ICC, IF, IP
VRX-0163Y
Mouse Anti-Ebola Virus NP Monoclonal Antibody (XY0022)
Mouse
NP
IP, WB, ELISA, IF
VRX-0170Y
Mouse Anti-Ebola Virus GP Monoclonal Antibody (XY0019)
Mouse
GP
ELISA, IHC-P, FCM, ICC, IF, IP
VRX-0172Y
Mouse Anti-Ebola Virus GP Monoclonal Antibody (XY0028)
Mouse
GP
Crystallization, IP, NTRL, IF
05
Anti-Ebola Virus Antibody Products and Services
Ebola Virus Antibody Products CAT#
Product Name
Host Species
Target
Application
VRX-0173Y
Mouse Anti-Ebola Virus GP Monoclonal Antibody (XY0029)
Mouse
GP
IP, SPR, ELISA
VRX-0175Y
Mouse Anti-Ebola Virus GP Monoclonal Antibody (XY0031)
Mouse
GP
WB, ELISA
VRX-0171Y
Rabbit Anti-Ebola Virus GP Polyclonal Antibody
Rabbit
GP
WB, IHC-P, IP
VRX-0176Y
Rabbit Anti-Ebola Virus GP Monoclonal Antibody (XY0032)
Rabbit
GP
ELISA
We offer antibody products conjugated with various fluorophores to facilitate your virology researches. We also provide conjugation services for any antibody products. CAT#
Product Name
Host Species
Target
Application
VRX-0121Y
Mouse Anti-Ebola Virus Monoclonal Antibody (XY0013)
Mouse
EBOV
WB, ELISA
VRX-0132Y
Mouse Anti-Ebola Virus Monoclonal Antibody (XY0013) [Biotin]
Mouse
EBOV
WB, ELISA
VRX-0129Y
Mouse Anti-Ebola Virus Monoclonal Antibody (XY0013) [Alexa Fluor 488]
Mouse
EBOV
WB, ELISA
VRX-0140Y
Mouse Anti-Ebola Virus Monoclonal Antibody (XY0013) [FITC]
Mouse
EBOV
ELISA
VRX-0141Y
Mouse Anti-Ebola Virus Monoclonal Antibody (XY0013) [HRP]
Mouse
EBOV
WB, ELISA
VRX-0138Y
Mouse Anti-Ebola Virus Monoclonal Antibody (XY0013) [DyLight 680]
Mouse
EBOV
WB, ELISA
06
Anti-Ebola Virus Antibody Products and Services
Ebola Virus Antibody Products We offer high quality antibody fragments to advance your virology researches. CAT#
Product Name
Host Species
Target
Application
VRV-0151R
Anti-EBOV Recombinant Antibody (VR0151)
Mouse
EBOV
ELISA
VRV-0425R
Anti-EBOV Recombinant Antibody Fab Fragment (VR0151)
Mouse
EBOV
ELISA
VRV-0699R
Anti-EBOV Recombinant Antibody scFv Fragment (VR0151)
Mouse
EBOV
ELISA
VRV-0159R
Anti-EBOV Recombinant Antibody (VR0159)
Mouse
EBOV
FuncS, WB
VRV-0433R
Anti-EBOV Recombinant Antibody Fab Fragment (VR0159)
Mouse
EBOV
FuncS, WB
VRV-0707R
Anti-EBOV Recombinant Antibody scFv Fragment (VR0159)
Mouse
EBOV
FuncS, WB
VRV-0175R
Anti-EBOV Recombinant Antibody (VR0175)
Human
EBOV
Neut
VRV-0449R
Anti-EBOV Recombinant Antibody Fab Fragment (VR0175)
Human
EBOV
Neut
VRV-0723R
Anti-EBOV Recombinant Antibody scFv Fragment (VR0175)
Human
EBOV
Neut
VRV-0176R
Anti-EBOV Recombinant Antibody (VR0176)
Human
EBOV
ELISA, Neut
VRV-0450R
Anti-EBOV Recombinant Antibody Fab Fragment (VR0176)
Human
EBOV
ELISA, Neut
VRV-0724R
Anti-EBOV Recombinant Antibody scFv Fragment (VR0176)
Human
EBOV
ELISA, Neut
VRV-0179R
Anti-EBOV Recombinant Antibody (VR0179)
Human
EBOV
ELISA (This is a VHH antibody)
07
Anti-Ebola Virus Antibody Products and Services
Ebola Virus Antibody Products CAT#
Product Name
Host Species
Target
Application
VRV-0177R
Anti-EBOV Recombinant Antibody (VR0177)
Macaque
EBOV
ELISA, Neut
VRV-0180R
Anti-EBOV Recombinant Antibody (VR0180)
Human
EBOV
ELISA, FuncS
Empowered with the established antibody library, we offer high efficient and cost effective antibody careening and production services for specific target peptide sequences. CAT#
Product Name
Host Species
Target
Application
VRH-01146F
Mouse Anti-Ebolavirus GP (GIYIEGLMHNQDGLI) Monoclonal Antibody (01146YF)
Mouse
GP
WB, ELISA, IHC-P, FCM, ICC, IF, IP
VRH-01153F
Mouse Anti-Ebolavirus GP (ELSFTVVSNGAKNIS) Monoclonal Antibody (01153YF)
Mouse
GP
WB, ELISA, IHC-P, FCM, ICC, IF, IP
VRH-01162F
Mouse Anti-Ebolavirus GP (RRTDNDSTASDTPSA) Monoclonal Antibody (01162YF)
Mouse
GP
WB, ELISA, IHC-P, FCM, ICC, IF, IP
VRH-01133F
Mouse Anti-Ebolavirus NP (GDYKLFLESGAVKYL) Monoclonal Antibody (01133YF)
Mouse
GP
WB, ELISA, IHC-P, FCM, ICC, IF, IP
VRH-01138F
Mouse Anti-Ebolavirus NP (KNSQKGQHIEGRQTQ) Monoclonal Antibody (01138YF)
Mouse
GP
WB, ELISA, IHC-P, FCM, ICC, IF, IP
VRH-01143F
Mouse Anti-Ebolavirus NP (QTQSRPIQNVPGPHR) Monoclonal Antibody (01143YF)
Mouse
GP
WB, ELISA, IHC-P, FCM, ICC, IF, IP
08
Anti-Ebola Virus Antibody Products and Services
Ebola Virus Antibody Development Services Empowered by unrivaled expertise and advances in virology areas, Creative Biolabs has developed integrated custom ViroAntibody solutions to tailor various requirements of your projects. We are dedicated to facilitating your projects, and being your trusted partner in advancing your virology researches.
ViroAntibody Discovery Services
ViroAntibody Engineering Services
ViroAntibody Customized Services
Creative Biolabs focuses on
Creative Biolabs can endow antibody
Creative Biolabs is executing highly
developing novel antibodies or
candidates with preferable properties
efficient strategies to satisfy your
equivalents with desired specificity
through our advanced analyzing and
custom demands of a comprehensive
and affinity for research, diagnostic,
engineering strategies...
suite of virology antibodies...
or therapeutic application...
09
Anti-Ebola Virus Antibody Products and Services
Creative Biolabs is dedicated to making your success our goal. We are committed to providing virology researchers with the highest quality antibodies so they may focus on their research.
Your satisfaction is our passion. Our mission, is your complete satisfaction with our ViroAntibody products.
USA
Europe
Tel: 1-631-381-2994
Tel: 44-207-097-1828
Fax: 1-631-207-8356
Email: info@creative-biolabs.com
Email: info@creative-biolabs.com
Heidenkampsweg 58, 20097
45-1 Ramsey Road, Shirley, NY 11967, USA
Hamburg, Germany
Contact us