2021/9/17 下午2:25
Applications of Calcium Imaging Technology in Nervous System Research - Creative Biolabs
Fig.2 The basic structure and principle of GCaMP protein (Ali Gheisari, 2017)
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Common Genetically Coded Calcium Indicator 1. GCaMP6 Series The sixth-generation GCaMP protein (GCaMP6) has three different subtypes: GCaMP6s, GCaMP6m, and GCaMP6f, which have different characteristics and need to be selected according to experimental requirements [3]. Calcium Indicators GCaMP6s
GCaMP6m
GCaMP6f
Features
Applications
Ultrasensitive GCaMP variant;
Suitable for low-frequency
slow kinetics
signals
Ultrasensitive GCaMP variant;
Suitable for high-frequency
medium kinetics
signals
Ultrasensitive GCaMP variant; fast kinetics
Wide range applications
2. jGCaMP7 Series jGCaMP7 (Janelia GCaMP7, different from G-CaMP7), including four types of proteins with different characteristics: jGCaMP7s, jGCaMP7f, jGCaMP7b, jGCaMP7c [2]. The jGCaMP7
sensors were tested in vitro and in vivo, and show substantially better performance than the GCaMP6 sensors. https://neuros.creative-biolabs.com/applications-of-calcium-imaging-technology-in-nervous-system-research.htm
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