Roles of Stem Cells in Cell-based Therapies

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Roles of Stem Cells in Cell-based Therapies Stem cells as drug-delivery vehicles • • •

Delivery of prodrug-converting enzymes Delivery of apoptosis-inducing agents Delivery of oncolytic viruses

Stem cells as therapeutics • • • •

Activation of antigen-specific immunity Endogenous tissue repair Stem cell-based gene therapy Stem cell-based gene editing Reference: Erin A. Kimbrel and Robert Lanza, Nature reviews, 2020

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