Juan Ansó, May 2015
Drill integrated neuro-monitoring for minimally invasive robotic cochlear implantation Background —
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Facial nerve safety – preliminary work —
Neuromonitoring for FN protection (detect FN proximity)
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Optimal stimulation protocol determined in sheep
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Custom neuromonitoring probe detects FN (<0.1 mm)
Project Goal —
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Cathode
Drill integrated stimulation for conitinuous FN monitoring Anode 3 Anode 2 Anode 1
Proposal — — —
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Drill passes within 0.3 – 1 mm of facial nerve
Protocol verification in humans (medical grade EMG device required) (Neurosign device, 17000 CHF )
FN
Drill bit insulation coating for integrated stimulation electrodes (Student 2.5 months ~ 14,000 CHF) Total budget 31,000 CHF, project duration 6 months
Collaborators —
Marco Caversaccio, Department of ENT, Unibe
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Jorg Patscheider, Coatings department, Empa
Stimulus threshold (mA)
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Sheep 2 Trajectory 7 LD = 0
d=2 d=4 d=7 Mono
1.5 1 0.5 0.3 0.1 -1
0 Axial distance (mm)
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NextStep - Scientific Collaboration 04.05.2015 - Tobia Brusa, ISTB, University Bern
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Functional anatomy of Fecal Incontinence (FI) — Characterization of continence organ’s anatomy and biomechanics in patients suffering from fecal incontinence (FI). — Prof. Dr. Med. Radu Tutuian, chief physician gastroenterology at Tiefeneau Hospital Bern — Chf: ~30’000.-
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Extension of current Nano-Tera study aiming at defining design specifications of implant based on healthy volunteers.
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Main benefit: add clinical component to the project — — — —
Comprehensive assessment of contraction and compliance Integration of imaging and functional data Establishing normal (healthy subjects vs. patients) Develop new treatment concepts 1
Digital Ultrasound Head [UltrasoundToGo] Pascal Alexander Hager largest ultrasound research unit Europe more than 20 years experience
Project Scope
Frontend HDI PCB (commercial components)
Digital Processing Digital high‐speed link
Piezoelectric Transducer Array
Backend System FPGA Board (Tablet/Smartphone)
Ultrasound Division Fraunhofer IBMT
ETHZ IIS
Conventional 2D Ultrasound System:
Goal: •
Explore new digital ultrasound head concept.
Collaboration: • •
Build two heads, collaborators provide parts Funding (30k): PCB, Components, IBMT Assistance
Time Table: Transducer head
Cable 64‐256 coax
Analog Frontend Digital Processing Backend System
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6 Month, 50% PhD Student IIS 10% support personnel IIS/IBMT
Image Sources: Ibmt.fraunhofer.de healthcare.philips.com www.akutron.com/products
Functional c-Si/GaAs nanowire tandem solar cell Flexible PDMS film helps to transfer GaAs nanowire forest from Si substrate to surface of c-Si solar cell
Problem with PDMS hardness – film with thickness 5 µm is very fragile Solution: perform search and analysis of different range of polymers with professional polymer chemist
Dmitry Mikulik, EPFL
1st Idea: Reliability of NW-polymer composite New polymer material – UV curable polyester. • High transparence • Low viscosity • Good adhesion • Good hardness
Main collaborator: Tommaso Nardi, Laboratory of Composite and Polymer Technology, EPFL Planning work: Work with different polymers and methods for embedding GaAs NWs on equipment of Polymer Lab in EPFL Our part: provide test samples with nanowires, analysis of experiments with SEM, OM and other techniques. Collaborator part: provide new polymer materials, expertise of methods of embedding NWs in polymer, provide equipment for experiments Funding: 5.000 chf
Sun light
Functional c-Si/GaAs nanowire tandem solar cell
ITO PDMS ITO c‐Si solar cell
2nd Idea: Reliability of GaAs NW solar cells by analyzing spectral and electrical characteristics Optical measurements: EQY – Initial measurements Reflectance — give information about surface quality IQY - depends on structure and p-n junction optical properties
GaAs p-i-n nanowires embedded in flexible PDMS film would play a role of second solar cell, placed on top of conventional c-Si solar cell Problem: Reliability of GaAs NW based solar cells Solution: To realize perspective and weak points of GaAs NW based solar cell - spectral, electric and optical measurements must be performed.
Dmitry Mikulik, EPFL
Electrical measurements: IV curves in a wide range of irradiance allows to obtain a number of important characteristics: Voc-Jsc dependence to form p-n junction IV curve resistive losses IV as a difference between p-n junction and practical IV curve
Electro-luminescence pattern determination at different temperatures: Could be applied to evaluate the uniformity of nanowires photo-electrical properties
T= 25C, J=100 mA/cm2
T= -190C, J=5 mA/cm2
T= -190C, J=5.5 mA/cm2
Main collaborator: Mikhail Mintairov, Photovoltaics Lab, Ioffe institute, Russia Planning work: Measurements and analysis of results of pilot devices in Photovoltaics lab in Ioffe institute Our part: provide pilot devices based on GaAs NWs, organize joint workshop/visit to discuss results Collaborator part: provide different measurements of solar cells, analysis of measurements Funding: 10.000 chf
PARTNERS
GOAL
Soft & dry biopotential electrodes MOTIVATION APPROACH
LBB
MNS
‐ Conductive polymers ‐ Implantables
‐ Micro & Nanofabrication ‐ Wearables
Flurin Stauffer
Moritz Thielen
FUNDING • Wearable health monitoring • Brain‐computer interfaces • Poor performance of Embedding conductive commercial systems nanostructures in soft substrates Contact: Moritz Thielen, thielenm@ethz.ch
Enobio from Neuroelectrics®
• A portable EEG system (12k) • Biocompatibility studies (8k) • Clinical evaluation (10k)
Development of an impedance setup to study electric and electrochemical bone tissue properties.
Thomas Wyss Balmer ISTB University of Berne
Facial nerve neuro‐monitoring is used to improve the safety of drilling in the bone for DCA. Bone electric properties required to predict the distance between drill bit and nerves. Electro‐chemical effects
Better characterization of these effects
Budget ~ 30’000 CHF
Contact effects Voltage/frequency dependent Affected by the type of electrolyte Collaboration with Department of Chemistry and Biochemistry at University of Bern & University of Budapest (P. Broeckmann, H. Siegenthaler) Setup for reliable measurement of the electrochemical properties (optimize stray capacitance, contact interface, signal/noise ratio, waveform…)
Cost of personnel & material Seed project towards snf proposal