Rpf catalogue products 2017

Page 1

RESEARCH PHARMACEUTICALS

Catalogue 2017 Cosmeceuticals Nutraceuticals Medical Devices

The effectiveness that makes the difference Information material reserved for Doctors and Pharmacists


The effectiveness that makes the difference.

Cosmeceuticals Nutraceuticals Medical Devices The RPF® (Search Pharmaceuticals) is a pharmaceutical company founded in 2001, located in Caserta (Italy). Specialized in the formulation of natural cosmeceuticals, nutraceuticals and medical devices, the RPF® test clinically its products making use of cooperation with universities and specialized laboratories. The RPF® products, for sale pharmacy, are presented to the medical community through our network of scientific informants.

The natural ingredients in cosmetics and nutrition, in the right concentrations, are now a reality proven effective. RPF® say: "we give to the body what the body knows"; the human body does not know the oil derivatives that represent a continuous and dangerous insult to our well-being. The use of preservatives and synthetic fragrances, often the cause of allergies in susceptible individuals, is minimized in our products. RPF®'s nutraceuticals, does not contain gluten, so they can be taken without problems also from celiac subjects. The company's team is the result of long experience. The objective is to provide cosmeceuticals, nutraceuticals and medical devices effective, safe and innovative. The products of RPF®, far from being static, are often subject to review and changes where we recognize the opportunity to make them more effective and safe, never satisfied with the excellent quality already achieved but always strive to improve them .

The RPF® with the collaboration of prestigious research institutes, universities, renowned consultants and advanced production laboratories, can boast a range of innovative and proven efficiency products, formulated and manufactured by adopting the latest knowledge in scientific research and according to the latest international guidelines, always striving to provide modern, effective and safe products.

The effectiveness that makes the difference.


PRODUCTS Specific products for the care of the skin and mucous membranes. Cream, fluid and liquid.

1-2

Plant extracts products, elective for the delicate skin of children and the elderly dystrophic ones.

3-4

Specific products for the delicate skin, hypersensitive, such as the children's ones.

5-8

Complete supplement for pregnancy and lactation. With 150 mg of Magnesium for capsule. In Softgel® capsules. Gluten free.

9-10

Acidifying vaginal ovules, antiseptics, resistant up to 54 ° C. With Lactospore®, Seeds Grapefruit and chlorhexidine.

11-12

Protective cleaner, antiseptic, sebum normalizing. Shampoo-shower.

13-14

Specific products for the care of the dystrophic skin and "diabetic foot".

15-16

Cream and Capsules Softgel® to counteract the disorders of microcirculation and edema of the face and body.

17-18

Dietary supplement of: Turmeric and Nettle for joint function, Vitamin E for antioxidant action, Vitamin D for the maintenance of healthy bones, Vitamin C for the formation of collagen, useful for the normal function of cartilage.

19-20

Food supplement: Vitis vinifera, Thiamine, EPA / DHA for normal cardiac function; vitamin C for collagen formation for the normal function of blood vessels; Folic Acid, Vitamin B6 and B12 for normal metabolism of homocysteine; vitamin E Vitamin C and Vitis vinifera for the antioxidant action. With Vitamin K2, Ubiquinol and Niacin.

21-22

Hypoallergenic cosmetics for face and body.

23-32

The effectiveness that makes the difference.


"Dry and irritated mucous membranes and skin do not tolerate alkaline soaps and sensitizing topical treatments." Anestin速 Liquido - It 's a liquid cleaner acting on lipid affinity at physiological pH. It 'a cleaning factor anogenital with strong refreshing and calming properties thanks to the presence of plant extracts, algae and oils that also provide a natural antibacterial and antifungal activities. It does not contain SOAPS and CHLORHEXIDINE. Medical Device CE. Anestin速 Fluido - Multipurpose treatment for anogenital area acting as a soothing, protective and lubricant product. Useful as moisturizing and lubricating in vaginal dryness and for an emergency cleansing without water. Dermatologically tested. Anestin速 Crema - The Anestin速 Cream allows to give immediate relief from itching, swelling, inflammation, irritation, skin burning and suffering mucous membranes. Dermatologically tested.

1


Anestin®

Medical Device CE

Anestin

®

Liquido

Physiological pH acid detergent for everyday anogenital cleansing. Devoid of soaps, acting on lipid affinity. Without foam. Package: 125 ml. Retail price in Italy: € 12,00 934829817

Anestin® Crema It give immediate relief from itching, swelling, inflammation, irritation, burning and suffering skin and mucous membranes. Package: 50 ml. Retail price in Italy: € 16,00

904367885

Anestin® Fluido Topical multipurpose treatment, acting as a soothing, protective and lubricant product, for the anogenital area. Also useful for cleansing without water. Package: 75 ml. Retail price in Italy: € 12,00 902725769

2


FidrenÂŽ Polvere FidrenÂŽ powder, thanks to the many active substances contained in it (Calendula, rice starch, corn starch, glycine, kaolin, zinc oxide, allantoin, triethyl citrate), guarantees the hygiene of the delicate and sensitive skin, gives the skin protection and softness and helps to improve the state of dystrophic skin. It avoids maceration, hinders the bacterial fermentation of perspiration, prevents the development of unpleasant odors. And it's indicated in all cases in which excessive perspiration and rubbing can cause irritation or unpleasant sensations. FidrenÂŽ powder forms on the skin a dry and uniform film which ensures protection from sweat. It's specifically formulated for armpits, skin folds, anogenital area, between toes. It's suitable for children, seniors, sports, long-term patients, obese, incontinent people. Bacteria present on the skin surface have enzymes that digest the sweat components resulting in the production of particular compounds (free fatty acids) which are the real culprits of our smell. The reaction is preferably carried out by these enzymes in hot humid environment and in the alkaline pH conditions. The Triethyl Citrate, attacked by bacteria present on the skin surface, absorbs, through the formation of complexes, the derivatives of malodorous enzymatic degradation. From the degradation of Triethyl Citrate molecule originates citric acid. Citric acid lowers the pH of the area by preventing the formation of short-chain fatty acid cause of the bad smell.

3


Fidren®

Fidren® Crema Adjuvant in acute and chronic disorders of skin and mucous membranes. Package: 75 ml. Retail price in Italy: € 15,00 902895352

Fidren® Olio Natural emollient and soothing effect. Only vegetal oils. Restores the skin barrier. Packages: 100 and 500 ml. Retail price in Italy: € 19,00 and € 45,00

900199934

905013797

Fidren® Polvere Absorbent and skin protecting. Deodorant for adsorption, not for chemical or fragrance action. Package: 100 g. Retail price in Italy: € 16,00

904734264

Fidren® Spray P Natural topical soothing treatment for insect bites. It acts also as insect repellent. Package: 50 ml. Retail price in Italy: € 10,00

903010268

4


Eladren速 Latte Eladren速 Latte is a creamy cleansing. It cleans without water at physiological acid and protective pH . It cleans with water at neutral pH. It ensures a soothing and protective effect on skin and mucous membranes when applied after cleansing. Eladren速 Latte cleanses for lipid affinity and not for foaming action. It 's a universal cleansing cream: suitable for cleansing the face and body, the newborn and the elderly. The cleaning effect is promoted by specific water-soluble plant extracts and oils that make the product multifunctional as it acts both without water and with water. It operates deep cleansing of the skin, frees the pores of impurities and gives the skin freshness and a better appearance. Indications: Eladren速 Latte has soothing and refreshing properties. Formulated for daily hygiene of the skin and mucous membranes. It is easily removable with water or with cotton wool. It's suitable for sensitive skin. It keeps the skin soft, clear and gives a feeling of wellbeing and facial cleansing. How to use: Without water with cotton wool. With water is used in place of soap for a gentle cleansing without foam.

On skin and mucous membranes, previously cleaned, massaging a small amount of product it will form a nourishing protective film.

It does not contain: alcohol, mineral oil, lanolin, parabens, nickel, chromium, and other heavy metals.

5


Eladren®

Eladren® Liquido Mild cleanser at physiological pH with acidand protective action for the skin and mucous membranes. Package: 250 and 500 ml. Retail price in Italy: € 10,00 and € 15,00

938011424

900162379

Eladren® Latte Creamy cleanser for the face and body of the mother and child. Cleans with or without water. Package: 200 ml. Retail price in Italy: € 16,00

905018786

Eladren® Emulsione Fluid emulsion nourishing, soothing and anti-itching. Elective in case of dystrophic and irritated skin . Package: 200 ml. Retail price in Italy: € 15,00

902574553

Eladren® Sole Moisturizing Sunscreen, soothing and protective with very high photoprotection (SPF 50) for delicate and sensitive skin. Package: 75 ml. Retail price in Italy: € 17,50 902895515

6


Eladren® Crema Multiattiva Eladren® Crema Multiattiva is an innovative multifunctional product that smoothes wrinkles and brightens the skin, summarizing in itself valid dermatological purposes; action exfoliating and rejuvenating is associated with average photoprotection to prevent and treat the damage of photoaging. Its formulation makes this beauty cream a unique product where the moisturizing action, firming and photoprotective effects are associated with the lightening, anti-aging and firming actions promoted by three new components, chosen for their specific characteristics and actions on the skin: the Azeloglicina®, the Pepha-Tight® and Matrixyl 3000®. Eladren® Crema Multiattiva, applied morning and evening after a light scrub cleanser, protects the elastic fibers from denaturation caused by free radicals and inhibits inflammation determined by exposure to environmental agents: hot-cold-wind-sun, etc. Also it restricts and prevents damage due to exposure to UVA / UVB, reduces skin dryness ensuring a lasting hydration .

The Eladren® Crema Multiattiva, thanks to the valuable and complex formulation, is useful to prevent skin aging . Designed to give new life to tired skin and marked by time, it is also ideal for young skin. Reduces wrinkles with a lifting effect, whitening, improving thickness, firmness and radiance of the skin. Eladren® Crema Multiattiva is elective to reduce hyperpigmentation making uniform the skin's color .

Indications: Prevention and Control of chronological skin aging (dryness and skin spots, wrinkles and expression lines) and protection from damage caused by external environmental factors (free radicals, sunlight...). Eladren® Crema Multiattiva , for cosmetic lifting effect, is indicated for the face, neck and chest.

7


Eladren®

Eladren® Crema Multiattiva Firming and anti-aging effects, lightening and moisturizing actions are exercised by Matrixyl 3000®, Azeloglicina®, Pepha-Tight® and Trealix®. With average photoprotection. Dermatologist tested.

Package: 75 ml. Retail price in Italy: € 34,00 902553318

Eladren® Spray Spray no gas, anti-aging, moisturizing, photoprotective (SPF25), for the whole body. Combats dry skin, glycation, oxidative stress, damage induced by UV, Chrono-aging and photo-aging. Dermatologist tested. Package:150 ml. Retail price in Italy: € 24,00 932135700

8


Matervit CAPSULE

AVERAGE VALUE ANALYSIS % LARN

(1 capsule)

Pregnancy

Apport 100 g

10 µg 70 µg 150 µg 400 µg 1 mg 1,1 mg 1,4 mg 2,2 µg 6 mg 10 mg 14 mg 70 mg 10 µg 55 µg 150 µg 1 mg 1,2 mg 7 mg 30 mg 150 mg

100

0,8 mg 5,5 mg 11,8 mg 31,6 mg 0,1 g 0,1 g 0,1 g 0,2 mg 0,5 g 0,8 g 1,1 g 5,5 g 0,8 mg 4,3 mg 11,8 mg 0,1 g 0,1 g 0,6 g 2,5 g 11,9 g

Daily apport Vitamina D3 Vitamina K Biotina Acido folico Tiamina Vitamina B6 Riboflavina Vitamina B12 Acido pantotenico Vitamina E Niacina Vitamina C Cromo Selenio Iodio Manganese Rame Zinco Ferro Magnesio

100 100 85 87,5 100

100 100 100 86 100 100 100

*Useful, 2 capsules, to alleviate premenstrual syndrome and for non-pharmacological prophylaxis of the uterine contractile activity resulting in prenatal diagnosis.

9


Matervit® Capsule

Product inserted into the Register of the Ministry of Health Code: 3015

Matervit®Capsule Multivitamin, multimineral complete for pregnancy and lactation, with 150 mg of magnesium 1 capsule.

Package: 30 capsules Softgel® Retail price in Italy: € 13,50

902644739

Therapeutic efficacy of Matervit® Capsule during Pregnancy and Lactation.

Authors: Giuseppe Vetrano, Federica D'Itri, Nizam Mohammad Aboulkhair, Patrick Messina, Vincenzo Aleandri Department of Gynecological Sciences, Perinatology and Childcare, University of Rome "La Sapienza."

Conclusions Respectively integration of Iron, Vitamin C and magnesium, such as that present in the Matervit® (30 mg, 70 mg, 150 mg) is able to reduce the incidence of anemia, especially in the last trimester of pregnancy and prevent muscle disorders , such as cramps and an increase in blood pressure. The presence of high doses of Magnesium in synergistic action with Vitamin B6, zinc and copper, makes the Matervit® elective to alleviate premenstrual syndrome taking two capsules a day.

10


Therapeutic efficacy of NinfaginÂŽ Vaginal Ovules in non-specific cervical-vaginal inflammation. Authors: GIUSEPPE Vetrano, MARIO GRASSO, ANTONELLA PALACE, ROBERTO Iacovelli, ERMELINDA BAIOCCO - University of Rome "La Sapienza." Figure 1 - The vaginal pH variation Scale.

Figure 2 - Splitting of glycogen with the release of glucose and formation of H2O2 and lactic acid.

Which H2O2 manufacturer protects the vaginal flora in case of cystitis.

11


Ninfagin® Ovuli Vaginali

Ninfagin® Ovuli Vaginali Vaginal ovules with acidifying , normalizing and broad-spectrum antimicrobial action. Package: 10 vaginal ovules. Retail price in Italy: € 14,00

902874318

Conclusions The Ninfagin®Ovuli Vaginali formulated with Lactospore®, Seeds Grapefruit, Chlorhexidine, Aloe Vera, Mallow, Arabinogalactan and Soy Lecithin, in addition to promoting a protective film on the mucous membranes stimulates the vaginal epithelial tropism inducing physiological hydration and normalization of the vaginal flora.

12


Cleanser rich in trace elements in acid solution, with principles with strong anti-microbial and anti-fungal actions The cleansing action is promoted by a mixture of amphoteric and non-ionic surfactants that provide gentle and sanitizing action on the skin, in addition to spread the product's active principles. Characteristics of the main components of Pantaskin® Plus: · Piroctone olamine, functional substance with sebum normalizing action; · Water-soluble sulfur, eudermic purifying substance. Its topical use ensures good results in the treatment of skin problems such as psoriasis, eczema and dermatitis in the various forms; particularly effective in the treatment of ringworm; · Acetic acid, acidifying with particular anti-microbial properties. It 'used to treat irritations caused by contact from jellyfish and in the case of proliferations of various insects; · Melaleuca alternifolia,plant with antimicrobial and fungicidal activity, acting also on body odor;

· Citric acid, acidity and pH adjuster. Pantaskin® Plus is complemented by soothing and refreshing ingredients such as: · Rice starch, with recognized gelling and soothing; · Panthenol, softening and moisturizing; · Urea, moisturizing and softening. Formulated to ensure a sanitizing cleansing, Pantaskin® Plus is recommended for use by the guests of communities, elderly, disabled, sports in the gym and in the pool.

13


Pantaskin® Plus

Tea tree oil Piroctone Olamine

Pantaskin® Plus Cleanser face / body with antibacterial, antifungal and sebum normalizing principles. Shampoo/Shower.

Package: 300 ml. Retail price in Italy: € 11,00

905526568

14


Specific products for the prevention and treatment of dystrophic skin and "DIABETIC FOOT".

Oil

Liquid

15

Cream


Eupoderma®

Eupoderma® Liquido Cleaning solution for the daily care of dystrophic skin and diabetic foot. Package: 300 ml. Retail price in Italy: € 11,00

930260599

Eupoderma® Olio Massage oil, counteracts the loss of elasticity and brittleness of dystrophic skin and diabetic foot. Package: 100 ml. Retail price in Italy: € 19,00 905022974

Eupoderma® Crema Specific cream for hydration and protection of dystrophic skin and diabetic foot. Package: 200 ml. Retail price in Italy: € 19,50

930260613

16


HO HO

Solidago

Rusco

O

OH O O

HO

O O O

HO

OH

OH

O

OH COOH

HO HO O

O

O OH

OH

Escina

Resveratrolo

Eudren Capsule ÂŽ

With specific antioxidants principles for the tropism of the microcirculation

OPC

and physiological diuresis without potassium seizure. Product inserted into the Register of the Ministry of Health Code:5112

Ginkgo Biloba

Meliloto

Curcuma

Rusco

EudrenÂŽ Crema Topical treatment face / body with

Ippocastano

Centella Asiatica

17

antioxidant, soothing, firming and toning properties.


Eudren®

Eudren® Capsule Dietary supplement: Horse Chestnut and Vitis vinifera for the function of the microcirculation, Rusco for the functionality of the venous circulation, Solidago for drainage of body liquids and function of the urinary tract, Turmeric, Maritime Pine, and Vitis vinifera for the antioxidant action . Gluten free. ORAC 1347.32 2 capsules Softgel®

Package: 30 Softgel®capsules Retail price in Italy: € 18,00

904045945

Eudren® Crema Topical treatment face / body with antioxidant, soothing, firming and toning properties. Activator of surface skin microcirculation, also opposes the hassle of heavy legs, swollen hands and ankles, various skin problems such as blotchiness, roughness, relaxation and edema. Package: 75 and 200 ml. Retail price in Italy: € 15,00 and € 28,00

902943834

903705919

18


Formulated with Turmeric, Bromelain, EPA and DHA, Nettle Extract, Bioperine and Vitamins C, D, E. AVERAGE VALUE ANALYSIS

The antioxidant capacity of two Flosil® capsules amounts to 1,880 ORAC units (Oxygen Radical Absorbance Capacity). Gluten free. The Flosil® capsules is particularly suitable for reducing the use of non-steroidal antiinflammatory. The Flosil® capsules, which plant complex, promotes more gradual but continuous action, not only symptomatic, but also regenerative: over time have also favored the physiological repair mechanisms such as in the joint area, contrasting the degeneration and the consequent destruction of tissues. The shape of the Softgel® capsules conveys never dusty active as such but always in the form of a suspension representing in itself a form more "prepared" to digestion and absorption. Package: 20 Softgel® capsules. Retail price in Italy: € 18,00

931967436

19


GL U FR TE EE N

Dietary supplement of: Turmeric and Nettle for joint function Vitamin E for antioxidant effect Vitamin D for the maintenance of healthy bones Vitamin C for the formation of collagen. Useful for the normal function of cartilage With Omega 3 and Pineapple

Adjuvant in drug therapies to reduce dosages and side effects 1880 ORAC 2 SoftgelÂŽ capsules

Not contraindicated in pregnancy

20 Product inserted into the Register of the Ministry of Health Code: 59175


Several factors can affect the balance of the cardiovascular system and the vascular endothelial function by altering the production of chemical mediators capable of adjusting the diameter and the elasticity of the vessels. The chemical mediators can be distinguished in vasodilators, which possess anti-proliferative, anti-thrombotic and anti-atherogenic effects, and vasoconstrictors, which instead have opposite function. Endothelial alterations arise when prevail pro-coagulant and pro-inflammatory activity . While a poor diet, poor lifestyle habits (sedentary lifestyle, etc ...) can cause a level of cholesterol accumulation predisposing vascular thrombotic events of various kinds, depending on the district in which they're going to happen (the lower limbs, heart, brain). Healthy eating habits, an active lifestyle, the limitation in the use of alcohol and smoking, can help reduce the occurrence of these alterations. Key component characteristics: QH®: reduced, active form of Coenzyme Q10 (CoQ10). It is absorbed directly by the body because more bioavailable of CoQ10. The use of statins is in connection with a low endogenous production of Coenzyme Q10 for inhibition of 3-hydroxy-3-methylglutaryl-coenzimaA (HMG-CoA) reductase. Omega-3 (EPA+DHA): contribute to support normal cardiac function. The beneficial effect is obtained with a daily intake of 250 mg of EPA and DHA, as recommended by the European Food Safety Authority (EFSA). MenaQ7®: Fat-soluble vitamin K2, in the form of Menaquinone-7, conveys to the bone system the Calcium in the blood circulation helping to maintain healthy bones, as well as to prevent the Calcium storage in the arteries. Folic acid, vitamins B6 and B12: contribute to normal homocysteine metabolism. Enovita™: extract with 95% content in procyanidins, it helps to maintain a normal blood pressure. Ester C®: Vitamin C patented, characterized by high bioavailability and a neutral pH that makes it well-tolerated at the gastrointestinal level. It contributes to normal collagen formation for the normal function of blood vessels. Vitamin E: It contributes to the protection of cells from oxidative stress.

Package: 20 Softgel®capsules. Retail price in Italy: € 24,00

21


Gluten Free 2376,15 ORAC 2 SoftgelÂŽ capsules Not controindicated in pregnancy Grape Seed Procyanidis in Pre and Mild Hypertension: A Registry Study (2013) Gianni Belcaro, Andrea Ledda, Shu Hu, Maria Rosa Cesarone, Beatrice Feragalli, and Mark Dugall

Beneficial clinical effects of grape seed proanthocyanidin extract on the progression of carotid atherosclerotic plaques (2015) Ai-Hong CAO, Jian WANG, Hai-Qing GAO, Ping ZHANG, Jie QIU

Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women: double-blind randomised clinical trial (2015) Mario H.J. Knapen, Lavienja A.J.L. Braam, Nadia E. Drummen, Otto Bekers, Arnold P.G. Hoeks, Cees Vermeer

Ubiquinol supplementation supports statin users Previous studies already showed ability of CoQ10 supplementation to decrease muscle pain (Caso et al, 2007) Recent study showed efficiency of Ubiquinol (Zlatohlavek L. et al, 2012) to decrease muscle pain (minus 53.8%) to decrease muscle weakness (minus 44.4%) to increase CoQ10 plasmatic [CoQ10] from 0.9mg/L to 2.6mg/L

22


Contrasting and reducing the wrinkles and dark circles around eyes with active ingredients in controlled-release: Idrastin® Gemme. A next-generation topical serum designed for the daily care of the skin around the eyes and face. Idrastin® Gemme carries out a bump for combat wrinkles and contour eyes imperfections, especially the darkening of the area periocular zone, and it is also suitable in the cosmetic treatment of rosacea. In particular the presence of Haloxyl ™ (combination of 3 active ingredients which act synergistically) it strengthens and tones the eye area, supports the microvascular network and reduces the phenomena of darkening. In vitro studies show that this component supports the natural process of elimination of pigment residues and relieves inflammation charged to the microcirculatory system. The formulation also has the valuable combination of Vitamin E and pure Retinol 0.03% in Microsponge® that regulates cell renewal, minimizes the surface wrinkles and makes the skin smooth and promotes the production of collagen improving skin elasticity. The original mix of elements reduces the visibility of the capillary layer in the suborbital area, promotes the removal process of melanin granules through cell renewal, stimulates collagen synthesis improving skin elasticity and inhibits the oxidative processes caused by ultraviolet. The effectiveness of the formulation is supported by a controlled release system Microsponge® that provides the skin the right amount of active ingredient on time. The single doses of Idrastin® Gemme (Vegicaps® Soft) contain the right amount of product for each application, thus avoiding the risk of contamination caused by repeated contact with people and environment.

23


Idrastin®

Idrastin® Crema Rigenerante Biostimulative wrinkle cream with lifting effect. Effective for eye's area and face. Package: 50 ml. Retail price in Italy: € 25,00 900360254

Idrastin® Gemme Regenerating Serum in single dose for face, eye's and lip's area. Package: 7 and 28 gems. Retail price in Italy: € 9,00 and € 28,00

939969414

903774444

24


The results of in vitro study on Idrastin®Siero and Idrastin®Gemme They are the result of a collaborative project between the Research Society Microna srl and the Center for the Evaluation of Toxicologic Risk of the University of Milan in order to assess the potential of cosmetic products for topical use through the use of reconstructed human skin models (EpiDerm ™, EpiDerm Full Thickness ™). The products subject to the investigation were Idrastin® Siero and Idrastin® Gemme. Idrastin® Siero showed a recovery of 388.71% and the data obtained suggest that the formulation proves to possess a good protective activity of keratinocytes. Idrastin® Gemme instead, showed a recovery of 237.10% and also for this formulation can evaluate a protective activity of keratinocytes. For regenerating effect, with Idrastin® Siero we have seen a 40% increase in collagen release in medium; a 10% increase in the release of collagen in tissue. After 5 days of treatment, in medium: 80% increase compared to the baseline and in the tissue: + 12% compared to baseline. After 8 days of treatment: in medium additional increase of 20% and in the tissue + 10% compared to baseline. Overall: + 40% collagen release in the medium and + 10% in the tissue. After 5 days of treatment with the formulation Idrastin® Gemme in the medium: more than 100% increase from baseline and in the tissue + 39% compared to baseline. And yet, after 8 days of treatment, in the medium a further increase of 56% . Overall the increase of collagen release was 70% in the medium and of 18% in the tissue. The study authors have reached the conclusion that this study has amply demonstrated protectiveregenerating-antinflammatory activity of the two products designed for topical use and their densification action of the dermis .

25


Idrastin®

Idrastin® Visage Anti-aging cream with Glycolic Acid 10% and Rosa Moscheta' s oil, moisturizing and smoothing for the face. Package: 50 ml. Retail price in Italy: € 25,80 905853964

Idrastin® Siero Dermatologicamente Strengthen the relaxed skin of face, neck, décolleté with densifying effect. Package: 50 ml. Retail price in Italy: € 69,00

932138403

Idrastin® Bioriattivante Tonico Face / body solution whith soothing effect. Suitable for application of face masks and as a daily tonic. Package: 300 ml. Retail price in Italy: € 20,00

900054343

Idrastin® Dermo Spray Spray Face / body decongestant to stressed or irritated skin. Elective for erythema. Package: 300 ml. Retail price in Italy: € 25,00

930439803

26


3 Collagen Sheets of high purity: Idrastin® Vello. The pack contains 3 preformed masks Idrastin® Vello based on native collagen activated with specific dermofunctional principles. The masks, formed by a weave of native collagen fibers, are characterized by efficacy, tolerability and high concentration of the active principle (more than 99% of collagen), absence of perfumes and preservatives and extremely high capacity to bind water (about 3000 times their weight) offering exceptional moisturizing properties. Soaked with Idrastin® Bioriattivante, the Collagen masks take on a gelatinous appearance that makes them easily moldable on the face. A soothing effect to the skin: the mask helps the skin to regain its natural balance quickly and effectively with an average reduction of 27.5% of the epidermal redness caused by UV rays. A smoothing effect on wrinkles and lines. The study show, 20 minutes after application, an average reduction of 15% of the depth of wrinkles around the eyes. A moisturizing effect: the mask increases the balance of water supply and improves the structure and firmness of the skin. Twenty minutes after the application has been found an average increase in skin hydration around the eyes of 59%. How to use: moisten with Idrastin® Bioriattivante, apply the Fleece on the face; leave for about 30 minutes before removing it. While applying the Fleece will take on a gelatinous appearance that will make it easy to model on the face. It is important to spray often the collagen sheet with Idrastin® Bioriattivante to be sure of the moisturizer and carrier action of active ingredients of the Fleece and of the precious thermal water enriched with vitamins, trace elements and plant extracts essential for healthy skin.

27


Idrastin®

Idrastin® Vello It Contains 3 sheets of collagen for moisturizing and repairing action. Package: 3 pure Collagen fleeces. Retail price in Italy: € 44,00

904436666

Idrastin® Maschera Lifting It contains 3 sheets of collagen with firming effect. Package: 3 Collagen fleeces with Hibiscus. Retail price in Italy: € 54,00

931341731

Idrastin® Trattamento viso Kit hydrating, toning, anti-aging, with 10 Collagen masks + Idrastin® Bioriattivante. Package: 10 Collagen fleeces+1Idrastin® Bioriattivante. Retail price in Italy: € 165,00 900095720

Idrastin® Fitogel Contains 3 face sets rich in micro-algae and Vitamin C with antioxidant, restorative and anti-inflammatory action. Package: 3 face sets. Retail price in Italy: € 44,00

904032240

28


Cleansing: Personal Hygiene Act - Cathartic Anti-Stress Ritual - Social need, improvement of Relationship Life - The cleansing is the removal of dirt. The exogenous dirt comes from environmental contamination and lies on "hydro-lipid film", which is on the stratum corneum, moisturizing it, giving it mechanical protection and allowing the development of bacterial flora resident. The endogenous dirt comes from tissue debris and from sebaceous and sweating secretions . A very useful practice is to add products for cleansing substances to specific DERMO-FUNCTIONAL activities like, for example, antibacterial disinfectants (chlorhexidine, undecylenic acid, piroctone olamine) or plant extracts with anti-inflammatory, soothing, antimicrobial (beta-enoxolone, mimosa tenuiflora, melaleuca alternifolia). To counteract the alkalinity phenomena are added weak organic acids and to preserve hydration are used replacement of the hydro-lipid film (film-forming).

CLEANSING NOT BALANCED MAY INDUCE A SERIES OF ALTERATIONS SUMMARIZED AS FOLLOWS: Alteration of the skin pH - Alteration of the skin flora - Dehydration and increased TEWL (trans-epidermal water loss) - irritating action - sensitizing action. These imbalances are correlated with a chain reaction: the delipidation resulting in the removal of substances dispersed in the hydro-lipid film involves the pH changes, and changes in skin flora, as well as dehydration and exposure of the stratum to physical and chemical aggressive agents (peeling, fissures), loss of barrier function, direct toxic phenomena with the release of chemical mediators of inflammation. Besides factor to an irritant dermatitis, such alterations induce the possibility of allergic sensitization in susceptible individuals. The stay on the skin of salts of Ca2+ and Mg2+ fatty acids, insoluble in water, can lead to occlusion of the follicular and the sweat ducts (Folliculitis Miliaria).

29


Idrastin®

Idrastin® Liquido Natural antimicrobial liquid detergent for delicate and dystrophic skin . Medical Device CE Package: 300 ml. Retail price in Italy: € 12,00 930132497

Idrastin® Intimo Cleanser at physiological acid pH for the anogenital area. Medical Device CE Package: 300 and 500 ml. Retail price in Italy: € 12,00 and € 16,00

931540621

931540619

Idrastin® Gommage Cleansing gel face / body with micro-spheres of Jojoba and Alpha Hydroxy Acids to purifying and sebumnormalizing action. Package: 200 ml. Retail price in Italy: € 16,00 904769332

30


IdrastinÂŽ Levigante Corpo Gel cream with Glycolic Acid 20%, for regenerating and anti-aging, high keratolytic power. Thanks to its exfoliating effect, which weakens the intracellular ties in the stratum corneum, the Glycolic acid accelerates cell tropism: the dead cells are replaced by younger cells, making a deep restructuring of the skin, making it more moisturized and smoother. Particularly suitable in cosmetic treatment of small scars, dry skin, stretch marks.

Indications: Moisturizing, smoothing and rejuvenating treatment for the body. Indicated to mitigate the roughness of the body and as a cosmetic treatment of stretch marks after childbirth, dietary and slimming cures.

IdrastinÂŽ Levigante Corpo Cream gel, with glycolic acid to 20%, for regenerating, surface smoothing and elasticizing effects. Package: 200 ml. Retail price in Italy: â‚Ź 38,00 905023178

31


Idrastin®

Idrastin® Crema Cellulite Specific treatment liporeducing for cellulitis. Package: 200 and 500 ml. Retail price in Italy: € 20,00 and € 40,00

902728005

900054281

Idrastin® Crema Corpo Firming and moisturizing cosmetic treatment for the body's daily well-being. Package: 200 and 500 ml. Retail price in Italy: € 20,00 and € 40,00

902874193

901683894

Idrastin® Crema Linfodrenante It improves skin surface microcirculation with draining, regenerating and restorative action. Package: 200 and 500 ml. Retail price in Italy: € 20,00 and € 40,00

904232446

904232459

Idrastin® Crema Smagliature Smoothing, firming. Specific for stretch marks during pregnancy. Package: 200 and 500 ml. Retail price in Italy: € 20,00 and € 42,00

902943859

907214795

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www.errepieffe.it info@errepieffe.it

RPF SRL

Via Sopra Grottole n.30/36 81020 Castel Morrone (CE)

Italy

tel +39 0823-399187 fax +39 0823-399870

Website: www.errepieffe.it E-mail: info@errepieffe.it

The effectiveness that makes the difference. Information material reserved for Doctors and Pharmacists


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