Scientific Programme: 1st International meeting of diabetes and bone

General information Venue

Accreditation

Hotel Columbus Via della Conciliazione, 33 - 00193 Roma, Italy Phone: +39 06 686 5435

The Italian National Commission for Continuing Medical Education has accredited this SIF SRL event n. 1841- 105289 (provider reference number - event reference number),“1st International Meeting of Diabetes and Bone” (7-8 November, 2014, Rome, Italy) for N. 8 (eight) Italian CME credits.

Language The official language of this live educational workshop will be English.

Simultaneous translation is provided from English to Italian and vice versa.

This programme has been designed in partnership with the Università Campus Bio-Medico di Roma (UCBM).

Organising secretariat EXCEMED - Excellence in Medical Education Salita San Nicola da Tolentino, 1/B - 00187 - Rome, Italy Programme Manager: Giovanna Rossi - info@excemed.org

Scientific Secretariat

This programme is endorsed by SID (Società Italiana di Diabetologia), SIE (Società Italiana di Endocrinologia) and SIOMMMS (Società Italiana dell’ Osteoporosi del Metabolismo Minerale e delle Malattie dello Scheletro).

Società di Formazione Internazionale SRL Scientific Provider No. 1841

Improving the patient's life through medical education www.excemed.org

All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This programme is made possible thanks to educational grants received from: Platinum grantor

EXCEMED - Excellence in Medical Education Representative Office Salita di San Nicola da Tolentino 1/B 00187 Rome, Italy.

T +39.06.420.413, F +39.06.420.413.677 Headquarters EXCEMED 14, Rue du Rhone, 1204 Geneva, Switzerland

Gold grantor

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Paolo Pozzilli University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Scientific organisers Silver grantor

Bronze grantor

Copyright © EXCEMED, 2014. All rights reserved.

Presidents

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Nicola Napoli University Campus Bio-Medico di Roma (UCBM) Washington University Rome, Italy

1st International meeting of diabetes and bone Background and Aim Diabetes is one of the fasting growing diseases in the western world and is becoming a huge problem in emerging economic power houses such as India and Asia and particularly China. The number of patients is staggering and the rate of newly diagnosed diabetics continues to grow.

This is especially as Type 2 diabetes mellitus (DMT2) is associated with obesity which in itself is becoming a global health problem.

Osteoporosis is another disease increasing due to aging populations and an accompanying increase in fractures. There are approximately 1.5 million fractures per year in the USA .The population suffering low bone density is about 44 million, of which about 14 million are osteoporotic. The cost of the disease has been estimated to be in the region of $22 billion annually. The mortality after a hip fracture is around 50 % in the first year.

Rising morbidity is accompanied by loss of independence. Despite effective drugs reducing the fracture burden by about 50-60% the disease is still not recognized, diagnosed, or treated.

Learning objectives By attending this live educational meeting the learners will be able to: • Assess fracture risk in diabetic patients • Utilise the latest pathophysiology of bone fragility in diabetes • Utilise the latest diagnostic tools and treatment options for diabetes related fractures

Target audience Endocrinologists, Diabetologists, Rheumatologists, Internal medicine and primary care physicians.

Faculty members Bo Abrahamsen

Luigi Gennari

Institute of Clinical Research, SDU Research Centre for Ageing and Osteoporosis, Department of Medicine M, Glostrup Hospital (Nord) Glostrup, Denmark

University of Siena “Santa Maria alle Scotte” Hospital Siena, Italy

Laurie Baggio Mt. Sinai Hospital Samuel Lunenfeld Research Institute Toronto, Ontario, Canada

Marco Baroni Clinica Medica University of Rome “La Sapienza” Rome, Italy

Dennis Black University of California San Francisco (UCSF) San Francisco, California, USA

Henry Bone Michigan Bone and Mineral Clinic PC University of Michigan Detroit, USA

Iacopo Chiodini Ospedale Maggiore Policlinico IRCCS Milan, Italy

Roberto Civitelli Division of Bone and Mineral Diseases Musculoskeletal Research Center Washington University School of Medicine St. Louis, Missouri, USA

Renate T. de Jongh VU Medical Center Amsterdam, The Netherlands

David Dempster College of Physicians and Surgeons of Columbia University Regional Bone Cente,Helen Hayes Hospital New York State Department of Health New York, USA

Rivka Dresner-Pollak Hadassah-Hebrew University Medical Center Jerusalem, Israel

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA

Paolo Falaschi University of “La Sapienza” Rome, Italy

Andrea Giustina University of Brescia Brescia, Italy

Didier Hans University of Lausanne Lausanne, Switzerland

Scientific programme

Scientific programme

Friday, 7 November 2014

17.30

10.00

Registration

10.45

Welcome and introduction S. Epstein (USA), N. Napoli (Italy), P. Pozzilli (Italy)

Chairpersons: S. Epstein (USA), G. Isaia (Italy)

Davide Lauro University of “Tor Vergata” Rome, Italy

11.30

L2

Osteoblasts in diabetic patients, too lazy or just insulin resistant?

R. Civitelli (USA)

09.00

L12

The obesity epidemic, and the central role of adipose tissue in metabolic disorders M. Baroni (Italy)

Animal models of diabetic bone disease.

Advantages and disadvantages L. McCabe (USA)

09.30

L13

Latest advances in technology to assess diabetic bone disease D. Hans (Switzerland)

10.00

L14

Bone histomorphometry and bone Markers D. Dempster (USA)

12.00

12.30

L3

L4

Session II

Diabetes and fractures. Is it a global health problem?

B. Abrahamsen (Denmark) Lunch

Chairpersons: B. Abrahamsen (Denmark), A. Giustina (Italy) 14.00

L5

Neuro endocrine, GUT hormones and Bone L. Baggio (Canada)

L6

Prevention of diabetes through bariatric surgery G. Mingrone (Italy)

15.00

L7

Policlinico Gemelli Università Cattolica del Sacro Cuore Rome, Italy

Vitamin D and diabetes R. de Jongh (The Netherlands)

15.30

L8

Pathophysiology of diabetic bone disease A. Schwartz (USA)

Nicola Napoli

16.00

Coffee Break

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Session III

The treatment of bone fragility in diabetic patients

"Foro Italico" University Rome, Italy

Geltrude Mingrone

Session IV Chairpersons: D.Lauro (Italy), S. Migliaccio (Italy)

Coffee Break

Session V Chairpersons: D. Dempster (USA), L. Gennari (Italy) 11.00

L15

Post transplant bone disease in diabetics S. Epstein (USA)

11.30

L16

The role of the anti-aging gene Sirtuin1 in Diabetes and Osteoporosis R. Dresner-Pollak (Israel)

12.00

L17

Lilly symposium - Not CME accredited Does Anabolic therapy have a role in the treatment of diabetic bone disease N. Napoli (Italy)

Chairpersons: I. Chiodini (Italy), A. Schwartz (USA)

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

16.30

Ann Schwartz

17.00

University of California San Francisco (UCSF) San Francisco, California, USA

Saturday, 8 November 2014

10.30

14.30

Paolo Pozzilli

End of the first day

New concepts and latest research directions in the pathophysiology of diabetes P. Pozzilli (Italy)

Univeristy of “La Sapienza” Rome, Italy

Silvia Migliaccio

18.30

L1

13.00

Biomedical Imaging Research Center Michigan State University East Lansing, MI, USA

Clinical round table and open debate H. Bone (USA), I. Chiodini (Italy), S. Epstein (USA) P. Falaschi (Italy), N. Napoli (Italy), A. Schwartz (USA)

11.00

Andrea Lenzi Laura McCabe

Design of clinical trials to evaluate skeletal benefit and risk in diabetic patients H. Bone (USA)

18.00

Session I

Giancarlo Isaia Unit of Geriatrics and Metabolic Bone Diseases. Molinette Hospital AO Città della Salute e della Scienza di Torino School of Geriatric Medicine University of Torino Italian Osteoporosis and Metabolic Bone Diseases Society (SIOMMMS) Torino, Italy

L11

L9

L10

Incretin based treatments or old fashion medications, from diabetes treatment to bone health N. Napoli (Italy) Implications for the treatment of osteoporosis in the diabetic patient N. Napoli (Italy)

12.30

Concluding remarks

13.00

End of the Meeting

1st International meeting of diabetes and bone Background and Aim Diabetes is one of the fasting growing diseases in the western world and is becoming a huge problem in emerging economic power houses such as India and Asia and particularly China. The number of patients is staggering and the rate of newly diagnosed diabetics continues to grow.

This is especially as Type 2 diabetes mellitus (DMT2) is associated with obesity which in itself is becoming a global health problem.

Osteoporosis is another disease increasing due to aging populations and an accompanying increase in fractures. There are approximately 1.5 million fractures per year in the USA .The population suffering low bone density is about 44 million, of which about 14 million are osteoporotic. The cost of the disease has been estimated to be in the region of $22 billion annually. The mortality after a hip fracture is around 50 % in the first year.

Rising morbidity is accompanied by loss of independence. Despite effective drugs reducing the fracture burden by about 50-60% the disease is still not recognized, diagnosed, or treated.

Learning objectives By attending this live educational meeting the learners will be able to: • Assess fracture risk in diabetic patients • Utilise the latest pathophysiology of bone fragility in diabetes • Utilise the latest diagnostic tools and treatment options for diabetes related fractures

Target audience Endocrinologists, Diabetologists, Rheumatologists, Internal medicine and primary care physicians.

Faculty members Bo Abrahamsen

Luigi Gennari

Institute of Clinical Research, SDU Research Centre for Ageing and Osteoporosis, Department of Medicine M, Glostrup Hospital (Nord) Glostrup, Denmark

University of Siena “Santa Maria alle Scotte” Hospital Siena, Italy

Laurie Baggio Mt. Sinai Hospital Samuel Lunenfeld Research Institute Toronto, Ontario, Canada

Marco Baroni Clinica Medica University of Rome “La Sapienza” Rome, Italy

Dennis Black University of California San Francisco (UCSF) San Francisco, California, USA

Henry Bone Michigan Bone and Mineral Clinic PC University of Michigan Detroit, USA

Iacopo Chiodini Ospedale Maggiore Policlinico IRCCS Milan, Italy

Roberto Civitelli Division of Bone and Mineral Diseases Musculoskeletal Research Center Washington University School of Medicine St. Louis, Missouri, USA

Renate T. de Jongh VU Medical Center Amsterdam, The Netherlands

David Dempster College of Physicians and Surgeons of Columbia University Regional Bone Cente,Helen Hayes Hospital New York State Department of Health New York, USA

Rivka Dresner-Pollak Hadassah-Hebrew University Medical Center Jerusalem, Israel

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA

Paolo Falaschi University of “La Sapienza” Rome, Italy

Andrea Giustina University of Brescia Brescia, Italy

Didier Hans University of Lausanne Lausanne, Switzerland

Scientific programme

Scientific programme

Friday, 7 November 2014

17.30

10.00

Registration

10.45

Welcome and introduction S. Epstein (USA), N. Napoli (Italy), P. Pozzilli (Italy)

Chairpersons: S. Epstein (USA), G. Isaia (Italy)

Davide Lauro University of “Tor Vergata” Rome, Italy

11.30

L2

Osteoblasts in diabetic patients, too lazy or just insulin resistant?

R. Civitelli (USA)

09.00

L12

The obesity epidemic, and the central role of adipose tissue in metabolic disorders M. Baroni (Italy)

Animal models of diabetic bone disease.

Advantages and disadvantages L. McCabe (USA)

09.30

L13

Latest advances in technology to assess diabetic bone disease D. Hans (Switzerland)

10.00

L14

Bone histomorphometry and bone Markers D. Dempster (USA)

12.00

12.30

L3

L4

Session II

Diabetes and fractures. Is it a global health problem?

B. Abrahamsen (Denmark) Lunch

Chairpersons: B. Abrahamsen (Denmark), A. Giustina (Italy) 14.00

L5

Neuro endocrine, GUT hormones and Bone L. Baggio (Canada)

L6

Prevention of diabetes through bariatric surgery G. Mingrone (Italy)

15.00

L7

Policlinico Gemelli Università Cattolica del Sacro Cuore Rome, Italy

Vitamin D and diabetes R. de Jongh (The Netherlands)

15.30

L8

Pathophysiology of diabetic bone disease A. Schwartz (USA)

Nicola Napoli

16.00

Coffee Break

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Session III

The treatment of bone fragility in diabetic patients

"Foro Italico" University Rome, Italy

Geltrude Mingrone

Session IV Chairpersons: D.Lauro (Italy), S. Migliaccio (Italy)

Coffee Break

Session V Chairpersons: D. Dempster (USA), L. Gennari (Italy) 11.00

L15

Post transplant bone disease in diabetics S. Epstein (USA)

11.30

L16

The role of the anti-aging gene Sirtuin1 in Diabetes and Osteoporosis R. Dresner-Pollak (Israel)

12.00

L17

Lilly symposium - Not CME accredited Does Anabolic therapy have a role in the treatment of diabetic bone disease N. Napoli (Italy)

Chairpersons: I. Chiodini (Italy), A. Schwartz (USA)

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

16.30

Ann Schwartz

17.00

University of California San Francisco (UCSF) San Francisco, California, USA

Saturday, 8 November 2014

10.30

14.30

Paolo Pozzilli

End of the first day

New concepts and latest research directions in the pathophysiology of diabetes P. Pozzilli (Italy)

Univeristy of “La Sapienza” Rome, Italy

Silvia Migliaccio

18.30

L1

13.00

Biomedical Imaging Research Center Michigan State University East Lansing, MI, USA

Clinical round table and open debate H. Bone (USA), I. Chiodini (Italy), S. Epstein (USA) P. Falaschi (Italy), N. Napoli (Italy), A. Schwartz (USA)

11.00

Andrea Lenzi Laura McCabe

Design of clinical trials to evaluate skeletal benefit and risk in diabetic patients H. Bone (USA)

18.00

Session I

Giancarlo Isaia Unit of Geriatrics and Metabolic Bone Diseases. Molinette Hospital AO Città della Salute e della Scienza di Torino School of Geriatric Medicine University of Torino Italian Osteoporosis and Metabolic Bone Diseases Society (SIOMMMS) Torino, Italy

L11

L9

L10

Incretin based treatments or old fashion medications, from diabetes treatment to bone health N. Napoli (Italy) Implications for the treatment of osteoporosis in the diabetic patient N. Napoli (Italy)

12.30

Concluding remarks

13.00

End of the Meeting

1st International meeting of diabetes and bone

Faculty members

Background and Aim

Bo Abrahamsen

Luigi Gennari

Institute of Clinical Research, SDU Research Centre for Ageing and Osteoporosis, Department of Medicine M, Glostrup Hospital (Nord) Glostrup, Denmark

University of Siena “Santa Maria alle Scotte” Hospital Siena, Italy

Diabetes is one of the fasting growing diseases in the western world and is becoming a huge problem in emerging economic power houses such as India and Asia and particularly China. The number of patients is staggering and the rate of newly diagnosed diabetics continues to grow.

This is especially as Type 2 diabetes mellitus (DMT2) is associated with obesity which in itself is becoming a global health problem.

Osteoporosis is another disease increasing due to aging populations and an accompanying increase in fractures. There are approximately 1.5 million fractures per year in the USA .The population suffering low bone density is about 44 million, of which about 14 million are osteoporotic. The cost of the disease has been estimated to be in the region of $22 billion annually. The mortality after a hip fracture is around 50 % in the first year.

Rising morbidity is accompanied by loss of independence. Despite effective drugs reducing the fracture burden by about 50-60% the disease is still not recognized, diagnosed, or treated.

Learning objectives By attending this live educational meeting the learners will be able to: • Assess fracture risk in diabetic patients • Utilise the latest pathophysiology of bone fragility in diabetes • Utilise the latest diagnostic tools and treatment options for diabetes related fractures

Target audience Endocrinologists, Diabetologists, Rheumatologists, Internal medicine and primary care physicians.

Laurie Baggio Mt. Sinai Hospital Samuel Lunenfeld Research Institute Toronto, Ontario, Canada

Marco Baroni Clinica Medica University of Rome “La Sapienza” Rome, Italy

Dennis Black University of California San Francisco (UCSF) San Francisco, California, USA

Henry Bone Michigan Bone and Mineral Clinic PC University of Michigan Detroit, USA

Iacopo Chiodini Ospedale Maggiore Policlinico IRCCS Milan, Italy

Roberto Civitelli Division of Bone and Mineral Diseases Musculoskeletal Research Center Washington University School of Medicine St. Louis, Missouri, USA

Renate T. de Jongh VU Medical Center Amsterdam, The Netherlands

David Dempster College of Physicians and Surgeons of Columbia University Regional Bone Cente,Helen Hayes Hospital New York State Department of Health New York, USA

Rivka Dresner-Pollak Hadassah-Hebrew University Medical Center Jerusalem, Israel

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA

Paolo Falaschi University of “La Sapienza” Rome, Italy

Andrea Giustina University of Brescia Brescia, Italy

Didier Hans University of Lausanne Lausanne, Switzerland

Scientific programme

Scientific programme

Friday, 7 November 2014

17.30

10.00

Registration

10.45

Welcome and introduction S. Epstein (USA), N. Napoli (Italy), P. Pozzilli (Italy)

Chairpersons: S. Epstein (USA), G. Isaia (Italy) 11.00

L1

Davide Lauro University of “Tor Vergata” Rome, Italy

11.30

L2

New concepts and latest research directions in the pathophysiology of diabetes P. Pozzilli (Italy) Osteoblasts in diabetic patients, too lazy or just insulin resistant?

R. Civitelli (USA)

12.00

L3

The obesity epidemic, and the central role of adipose tissue in metabolic disorders M. Baroni (Italy)

12.30

L4

Diabetes and fractures. Is it a global health problem?

B. Abrahamsen (Denmark)

Andrea Lenzi

13.00

Univeristy of “La Sapienza” Rome, Italy

Session II

Laura McCabe

Chairpersons: B. Abrahamsen (Denmark), A. Giustina (Italy)

Biomedical Imaging Research Center Michigan State University East Lansing, MI, USA

Silvia Migliaccio

14.00

Lunch

L5

Neuro endocrine, GUT hormones and Bone L. Baggio (Canada)

Session IV Chairpersons: D.Lauro (Italy), S. Migliaccio (Italy) 09.00

L12

Animal models of diabetic bone disease.

Advantages and disadvantages L. McCabe (USA)

09.30

L13

Latest advances in technology to assess diabetic bone disease D. Hans (Switzerland)

10.00

L14

Bone histomorphometry and bone Markers D. Dempster (USA)

10.30

Coffee Break

Session V Chairpersons: D. Dempster (USA), L. Gennari (Italy) L15

Post transplant bone disease in diabetics S. Epstein (USA)

11.30

L16

The role of the anti-aging gene Sirtuin1 in Diabetes and Osteoporosis R. Dresner-Pollak (Israel)

12.00

L17

Does Anabolic therapy have a role in the treatment of diabetic bone disease N. Napoli (Italy)

L7

Vitamin D and diabetes R. de Jongh (The Netherlands)

15.30

L8

Pathophysiology of diabetic bone disease A. Schwartz (USA)

Nicola Napoli

16.00

University of California San Francisco (UCSF) San Francisco, California, USA

Saturday, 8 November 2014

11.00

15.00

Ann Schwartz

End of the first day

Prevention of diabetes through bariatric surgery G. Mingrone (Italy)

Policlinico Gemelli Università Cattolica del Sacro Cuore Rome, Italy

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

18.30

L6

Geltrude Mingrone

Paolo Pozzilli

Clinical round table and open debate D.Black (USA), H. Bone (USA), I. Chiodini (Italy) S. Epstein (USA), P. Falaschi (Italy), N. Napoli (Italy) A. Schwartz (USA)

14.30

"Foro Italico" University Rome, Italy

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Design of clinical trials to evaluate skeletal benefit and risk in diabetic patients H. Bone (USA)

18.00

Session I

Giancarlo Isaia Unit of Geriatrics and Metabolic Bone Diseases. Molinette Hospital AO Città della Salute e della Scienza di Torino School of Geriatric Medicine University of Torino Italian Osteoporosis and Metabolic Bone Diseases Society (SIOMMMS) Torino, Italy

L11

Coffee Break

Session III

The treatment of bone fragility in diabetic patients

Lilly symposium - Not CME accredited

Chairpersons: I. Chiodini (Italy), A. Schwartz (USA) 16.30

17.00

L9

L10

Incretin based treatments or old fashion medications, from diabetes treatment to bone health N. Napoli (Italy) Implications for the treatment of osteoporosis in the diabetic patient D.Black (Usa)

12.30

Concluding remarks

13.00

End of the Meeting

1st International meeting of diabetes and bone

Faculty members

Background and Aim

Bo Abrahamsen

Luigi Gennari

Institute of Clinical Research, SDU Research Centre for Ageing and Osteoporosis, Department of Medicine M, Glostrup Hospital (Nord) Glostrup, Denmark

University of Siena “Santa Maria alle Scotte” Hospital Siena, Italy

Diabetes is one of the fasting growing diseases in the western world and is becoming a huge problem in emerging economic power houses such as India and Asia and particularly China. The number of patients is staggering and the rate of newly diagnosed diabetics continues to grow.

This is especially as Type 2 diabetes mellitus (DMT2) is associated with obesity which in itself is becoming a global health problem.

Osteoporosis is another disease increasing due to aging populations and an accompanying increase in fractures. There are approximately 1.5 million fractures per year in the USA .The population suffering low bone density is about 44 million, of which about 14 million are osteoporotic. The cost of the disease has been estimated to be in the region of $22 billion annually. The mortality after a hip fracture is around 50 % in the first year.

Rising morbidity is accompanied by loss of independence. Despite effective drugs reducing the fracture burden by about 50-60% the disease is still not recognized, diagnosed, or treated.

Learning objectives By attending this live educational meeting the learners will be able to: • Assess fracture risk in diabetic patients • Utilise the latest pathophysiology of bone fragility in diabetes • Utilise the latest diagnostic tools and treatment options for diabetes related fractures

Target audience Endocrinologists, Diabetologists, Rheumatologists, Internal medicine and primary care physicians.

Laurie Baggio Mt. Sinai Hospital Samuel Lunenfeld Research Institute Toronto, Ontario, Canada

Marco Baroni Clinica Medica University of Rome “La Sapienza” Rome, Italy

Dennis Black University of California San Francisco (UCSF) San Francisco, California, USA

Henry Bone Michigan Bone and Mineral Clinic PC University of Michigan Detroit, USA

Iacopo Chiodini Ospedale Maggiore Policlinico IRCCS Milan, Italy

Roberto Civitelli Division of Bone and Mineral Diseases Musculoskeletal Research Center Washington University School of Medicine St. Louis, Missouri, USA

Renate T. de Jongh VU Medical Center Amsterdam, The Netherlands

David Dempster College of Physicians and Surgeons of Columbia University Regional Bone Cente,Helen Hayes Hospital New York State Department of Health New York, USA

Rivka Dresner-Pollak Hadassah-Hebrew University Medical Center Jerusalem, Israel

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA

Paolo Falaschi University of “La Sapienza” Rome, Italy

Andrea Giustina University of Brescia Brescia, Italy

Didier Hans University of Lausanne Lausanne, Switzerland

Scientific programme

Scientific programme

Friday, 7 November 2014

17.30

10.00

Registration

10.45

Welcome and introduction S. Epstein (USA), N. Napoli (Italy), P. Pozzilli (Italy)

Chairpersons: S. Epstein (USA), G. Isaia (Italy) 11.00

L1

Davide Lauro University of “Tor Vergata” Rome, Italy

11.30

L2

New concepts and latest research directions in the pathophysiology of diabetes P. Pozzilli (Italy) Osteoblasts in diabetic patients, too lazy or just insulin resistant?

R. Civitelli (USA)

12.00

L3

The obesity epidemic, and the central role of adipose tissue in metabolic disorders M. Baroni (Italy)

12.30

L4

Diabetes and fractures. Is it a global health problem?

B. Abrahamsen (Denmark)

Andrea Lenzi

13.00

Univeristy of “La Sapienza” Rome, Italy

Session II

Laura McCabe

Chairpersons: B. Abrahamsen (Denmark), A. Giustina (Italy)

Biomedical Imaging Research Center Michigan State University East Lansing, MI, USA

Silvia Migliaccio

14.00

Lunch

L5

Neuro endocrine, GUT hormones and Bone L. Baggio (Canada)

Session IV Chairpersons: D.Lauro (Italy), S. Migliaccio (Italy) 09.00

L12

Animal models of diabetic bone disease.

Advantages and disadvantages L. McCabe (USA)

09.30

L13

Latest advances in technology to assess diabetic bone disease D. Hans (Switzerland)

10.00

L14

Bone histomorphometry and bone Markers D. Dempster (USA)

10.30

Coffee Break

Session V Chairpersons: D. Dempster (USA), L. Gennari (Italy) L15

Post transplant bone disease in diabetics S. Epstein (USA)

11.30

L16

The role of the anti-aging gene Sirtuin1 in Diabetes and Osteoporosis R. Dresner-Pollak (Israel)

12.00

L17

Does Anabolic therapy have a role in the treatment of diabetic bone disease N. Napoli (Italy)

L7

Vitamin D and diabetes R. de Jongh (The Netherlands)

15.30

L8

Pathophysiology of diabetic bone disease A. Schwartz (USA)

Nicola Napoli

16.00

University of California San Francisco (UCSF) San Francisco, California, USA

Saturday, 8 November 2014

11.00

15.00

Ann Schwartz

End of the first day

Prevention of diabetes through bariatric surgery G. Mingrone (Italy)

Policlinico Gemelli Università Cattolica del Sacro Cuore Rome, Italy

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

18.30

L6

Geltrude Mingrone

Paolo Pozzilli

Clinical round table and open debate D.Black (USA), H. Bone (USA), I. Chiodini (Italy) S. Epstein (USA), P. Falaschi (Italy), N. Napoli (Italy) A. Schwartz (USA)

14.30

"Foro Italico" University Rome, Italy

University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Design of clinical trials to evaluate skeletal benefit and risk in diabetic patients H. Bone (USA)

18.00

Session I

Giancarlo Isaia Unit of Geriatrics and Metabolic Bone Diseases. Molinette Hospital AO Città della Salute e della Scienza di Torino School of Geriatric Medicine University of Torino Italian Osteoporosis and Metabolic Bone Diseases Society (SIOMMMS) Torino, Italy

L11

Coffee Break

Session III

The treatment of bone fragility in diabetic patients

Lilly symposium - Not CME accredited

Chairpersons: I. Chiodini (Italy), A. Schwartz (USA) 16.30

17.00

L9

L10

Incretin based treatments or old fashion medications, from diabetes treatment to bone health N. Napoli (Italy) Implications for the treatment of osteoporosis in the diabetic patient D.Black (Usa)

12.30

Concluding remarks

13.00

End of the Meeting

General information Venue

Accreditation

Hotel Columbus Via della Conciliazione, 33 - 00193 Roma, Italy Phone: +39 06 686 5435

The Italian National Commission for Continuing Medical Education has accredited this SIF SRL event n. 1841- 105289 (provider reference number - event reference number),“1st International Meeting of Diabetes and Bone” (7-8 November, 2014, Rome, Italy) for N. 8 (eight) Italian CME credits.

Language The official language of this live educational workshop will be English.

Simultaneous translation is provided from English to Italian and vice versa.

This programme has been designed in partnership with the Università Campus Bio-Medico di Roma (UCBM).

Organising secretariat EXCEMED - Excellence in Medical Education Salita San Nicola da Tolentino, 1/B - 00187 - Rome, Italy Programme Manager: Giovanna Rossi - info@excemed.org

Scientific Secretariat

This programme is endorsed by SID (Società Italiana di Diabetologia), SIE (Società Italiana di Endocrinologia) and SIOMMMS (Società Italiana dell’ Osteoporosi del Metabolismo Minerale e delle Malattie dello Scheletro).

Società di Formazione Internazionale SRL Scientific Provider No. 1841

Improving the patient's life through medical education www.excemed.org

All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This programme is made possible thanks to educational grants received from: Platinum grantor

EXCEMED - Excellence in Medical Education Representative Office Salita di San Nicola da Tolentino 1/B 00187 Rome, Italy.

T +39.06.420.413, F +39.06.420.413.677 Headquarters EXCEMED 14, Rue du Rhone, 1204 Geneva, Switzerland

Gold grantor

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Paolo Pozzilli University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Scientific organisers Silver grantor

Bronze grantor

Copyright © EXCEMED, 2014. All rights reserved.

Presidents

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Nicola Napoli University Campus Bio-Medico di Roma (UCBM) Washington University Rome, Italy

General information Venue

Accreditation

Hotel Columbus Via della Conciliazione, 33 - 00193 Roma, Italy Phone: +39 06 686 5435

The Italian National Commission for Continuing Medical Education has accredited this SIF SRL event n. 1841- 105289 (provider reference number - event reference number),“1st International Meeting of Diabetes and Bone” (7-8 November, 2014, Rome, Italy) for N. 8 (eight) Italian CME credits.

Language The official language of this live educational workshop will be English.

Simultaneous translation is provided from English to Italian and vice versa.

This programme has been designed in partnership with the Università Campus Bio-Medico di Roma (UCBM).

Organising secretariat EXCEMED - Excellence in Medical Education Salita San Nicola da Tolentino, 1/B - 00187 - Rome, Italy Programme Manager: Giovanna Rossi - info@excemed.org

Scientific Secretariat

This programme is endorsed by SID (Società Italiana di Diabetologia), SIE (Società Italiana di Endocrinologia) and SIOMMMS (Società Italiana dell’ Osteoporosi del Metabolismo Minerale e delle Malattie dello Scheletro).

Società di Formazione Internazionale SRL Scientific Provider No. 1841

Improving the patient's life through medical education www.excemed.org

All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This programme is made possible thanks to educational grants received from: Platinum grantor

EXCEMED - Excellence in Medical Education Representative Office Salita di San Nicola da Tolentino 1/B 00187 Rome, Italy.

T +39.06.420.413, F +39.06.420.413.677 Headquarters EXCEMED 14, Rue du Rhone, 1204 Geneva, Switzerland

Gold grantor

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Paolo Pozzilli University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Scientific organisers Silver grantor

Bronze grantor

Copyright © EXCEMED, 2014. All rights reserved.

Presidents

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Nicola Napoli University Campus Bio-Medico di Roma (UCBM) Washington University Rome, Italy

General information Venue

Accreditation

Hotel Columbus Via della Conciliazione, 33 - 00193 Roma, Italy Phone: +39 06 686 5435

The Italian National Commission for Continuing Medical Education has accredited this SIF SRL event n. 1841- 105289 (provider reference number - event reference number),“1st International Meeting of Diabetes and Bone” (7-8 November, 2014, Rome, Italy) for N. 8 (eight) Italian CME credits.

Language The official language of this live educational workshop will be English.

Simultaneous translation is provided from English to Italian and vice versa.

This programme has been designed in partnership with the Università Campus Bio-Medico di Roma (UCBM).

Organising secretariat EXCEMED - Excellence in Medical Education Salita San Nicola da Tolentino, 1/B - 00187 - Rome, Italy Programme Manager: Giovanna Rossi - info@excemed.org

Scientific Secretariat

This programme is endorsed by SID (Società Italiana di Diabetologia), SIE (Società Italiana di Endocrinologia) and SIOMMMS (Società Italiana dell’ Osteoporosi del Metabolismo Minerale e delle Malattie dello Scheletro).

Società di Formazione Internazionale SRL Scientific Provider No. 1841

Improving the patient's life through medical education www.excemed.org

All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This programme is made possible thanks to educational grants received from: Platinum grantor

EXCEMED - Excellence in Medical Education Representative Office Salita di San Nicola da Tolentino 1/B 00187 Rome, Italy.

T +39.06.420.413, F +39.06.420.413.677 Headquarters EXCEMED 14, Rue du Rhone, 1204 Geneva, Switzerland

Gold grantor

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Paolo Pozzilli University Campus Bio-Medico di Roma (UCBM) Rome, Italy

Scientific organisers Silver grantor

Bronze grantor

Copyright © EXCEMED, 2014. All rights reserved.

Presidents

Sol Epstein Mt. Sinai School of Medicine New York, NY, USA Nicola Napoli University Campus Bio-Medico di Roma (UCBM) Washington University Rome, Italy