How Does Nodular Melanoma Begin? Nodular melanoma is a type of skin cancer. It’s a dangerous form of melanoma that grows very quickly. However, only about 15% of all melanomas are nodular. But, it causes nearly half of melanoma-related deaths. So, it’s very important to know the signs. If it’s found early on, doctors may be able to cure it. In nodular melanoma, malignant melanoma cells proliferate downwards through the skin and this is known as vertical growth. The lesion presents as a nodule that has been rapidly enlarging over the previous weeks or even months. A nodular melanoma can penetrate deeply within the skin within a few months of its first appearance.
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