STEMPEL COLLEGE STUDENTS M A K E A N I M P A C T.
PH.D. CANDIDATE WINS AWARD FOR RESEARCH ON CHILDHOOD DYSTONIA-PARKINSONISM Doctoral student Alexander Rodichkin won a top honor in a graduate-level competition organized by the Metals Specialty Section at the virtual annual meeting of the Society of Toxicology. His poster presentation took second place in the Metals Specialty Section among students from the United States and abroad. The entry describes his three-year study on the pathophysiology of toxic brain manganese concentrations in a mouse model of childhood dystonia-parkinsonism that occurs in humans as a result of a genetic mutation. His work examined the behavioral, neurochemical and neuropathological consequence of toxic brain manganese concentrations resulting from the global deletion of the manganese transporter gene SLC39A14. He showed that this animal model expresses many of the neurological characteristics of the human disease.
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