5 minute read
To Seal or Not to Seal?
by GENEX
Introducing UdderLife™ OptiShield™ Teat Sealant
By Suzanne Lois, Herd Care Line Advisor
Mastitis has a large economic impact on a dairy's bottom line. Research indicates the direct and indirect costs, which include veterinary, discarded milk, extra labor, cow mortality, repeat cases and milk losses, amount to $1.7 - $2 billion per year. Preventive protocols are the best option to curb 50-60% of all new cases that occur during the dry period. Dry cow antibiotic therapy has been the most widely used method until recently. With the movement to reduce antibiotic use and regulations preventing organic dairy farms to use dry cow antibiotic therapy, teat sealants have been added to protocols or even used exclusively.
Understanding the physical barriers of a cow’s mammary system and the stages of the dry period can help producers make a fact-based decision whether to add a teat sealant to their dry cow protocol.
Understanding the Cow's Mammary System
The streak canal, teat sphincter and keratin plug make up the three physical barriers that block or absorb bacteria that may penetrate a cow’s mammary system.
The streak canal is the primary line of defense. It has built-in defense mechanisms, such as physical closing of the entryway into the gland and the formation of a keratin plug to prevent bacteria entry.
The teat sphincter, located in the teat wall, has no antibacterial activity, but rather contracts and shuts off the streak canal to create a physical obstruction to bacteria. Genetics can play a role in how quickly and tightly this smooth muscle closes after milking. Clinical and subclinical milk fever can also impact time of closure, as low calcium and magnesium levels affect all smooth muscle contraction.
The keratin plug has two functions. It is a mesh-like substance formed by desquamated epithelial cells, fatty acids and cationic proteins. It functions as a physical obstruction and can absorb bacteria. However, certain bacteria can survive and grow in the keratin plug. It is also bactericidal and bacteriostatic; it contains proteins that bind to and cause disintegration of gram-positive bacterial cell walls as well as compounds that inhibit the growth of bacteria. The fatty acid composition of the keratin plug is heritable too.
Understanding the Stages of the Dry Period
The involution stage of the dry period starts when daily milking stops. The udder reduces activity, gets smaller, and the keratin plug forms. The rate of delayed or never-formed keratin plugs are as follows: 50% of quarters fail to form a keratin plug 7-10 days after dry off, and 10‐23% of quarters fail to form a keratin plug 42-50 days after dry off.
During the steady state of the dry period, there are no mammary secretions of any kind. This allows the mammary system to recover for maximum production in the next lactation. Shortening the dry period two weeks reduces future production. This is a lower-risk stage when it comes to new infections.
The final stage, colostrogenesis, lasts about two weeks and is when colostrum production and the start of lactation occurs. New infections are likely to occur during this stage for three main reasons: 1) dry cow therapy is at a level below minimum inhibitory concentration; 2) the cow has a suppressed immune system; and 3) the keratin plug may break down or was never formed during involution.
The real question is did she or didn’t she form a keratin plug?
Unless every udder is x-rayed at dry off, there is no way of knowing if she formed a keratin plug. It is known, however, that the keratin plug plays a vital role in killing bacteria already present in the streak canal at dry off and blocking any new bacteria from entering the streak canal.
Will a Teat Sealant make the Difference?
When a teat sealant is deposited in the lower portion of the steak canal, it instantly mimics the keratin plug and seals off the teat for the entire dry period, blocking bacteria from entering the mammary system via the teat canal. It remains in the streak canal until it is manually stripped from the teat or a calf suckles the teat.
Studies have shown the efficacy of a teat sealant used in conjunction with antibiotic dry cow therapy can reduce new dry cow infections at calving by 25%.
What to Look for in a Teat Sealant
Most internal teat sealants have the same key ingredients: bismuth subnitrate (a heavy metal used in the pharmaceutical industry) and a mineral oil base (viscous paste).
The type of tube and the manufacturing process make all the difference when it comes to keeping a teat sealant in the lower part of streak canal.
Excess amounts of air in the tube can push the teat sealant further up into the streak canal and lower mammary system, requiring extra time for the teat sealant to completely clear. Teat sealants can clog milk filters and interfere with electronic switches in milking equipment.
Tubes with a tip that allow for a choice of full or partial insertion can push teat sealants up too far in the teat canal and require additional training for compliance and 100% consistency. Udder edema can also push the teat sealant above the streak canal and take longer to strip out.
Furthermore, most products on the market are made overseas, which can mean waiting on backordered product or limited availability.
UdderLife™ OptiShield™ teat sealant is the product of choice because it addresses all these issues.
Its unique manufacturing process prevents large amounts of air in each tube. The tube design allows for escape of any additional air during administration, so the teat sealant stays in the lower portion of the streak canal.
The tubes are partial insertion only, so there is no confusion when it comes to administration and provides a more consistent delivery.
It’s manufactured in the USA, so concerns over backordered or unavailable product are minimal.
Teat sealants are another tool to help cows block new dry cow mastitis cases and can increase profit to bottom lines. When considering any new dry cow therapy, it is best to consult with a team of professionals. If adding a teat sealant to dry cow therapy, UdderLife™ OptiShield™ teat sealant from GENEX can help seal off those profit-robbing new cases of mastitis.
References available upon request.