It Might Feel Wild & Wooly (particularly on Bill’s game days), But the Thruway Has Been Getting Safer for Decades.... Pg. 27
Twisting atomically thin materials could advance quantum computers Pg. 12
Researchers explore how mechanical signals influence viral infections in lungs Pg. 18
Student Article: CRISPR Genomic Engineering as a Tool to Develop Functional 3D Bioprinted Models Pg. 21
ENTERPRISE LEVEL
CHAMPION LEVEL
About RES
RES Mission Statement:
The RES will become the lead organization for improving the image and influence of the engineering community in the greater Rochester area by: Demonstrating a comprehensive knowledge of the region’s engineering and technical capabilities; Providing the best clerical support and public relations assistance to our affiliates; Continually communicating the engineering and technical accomplishments to both the engineering and technical community and the public; Providing regular forums and networking opportunities for the exchange of ideas and discussion of issues; and, Providing programs that identify career opportunities to the region’s youth and develop the skills of the practicing engineer.
The deadline is the 10th day of the month prior to the issue Unless otherwise stated, opinions expressed in this publication are those of contributors, not of the Rochester Society, Inc.
Advertising information may be obtained by contacting the office of the Rochester Engineering Society or going to the website at www.roceng.org.
Published quarterly, four issues electronically. You can purchase individual copies directly from ISSUU. 2,500+ Circulation ISSN 0035-7405
Go to www.roceng.org to join the Rochester Engineering Society. Click on the individual membership and you can submit your application on-line.
News items and articles are invited.
Materials should be submitted to e-mail: therochesterengineer@gmail.com www.roceng.org.
Stay up to date with the Rochester Engineering Society & their affiliates events by going to: https://roceng.org/Calendar
Campus
Campus
Board of Directors:
Executive Board
President
DENNIS ROOTE, PE
CDE Engineering & Environment, PLLC
dennis.roote@cde-pllc.com
Treasurer / Imm. Past President
MICHELLE SOMMERMAN, PE
Colliers Engineering
Michelle.Sommerman@collierseng.com
HOWARD RESSEL, PE
Directors
Popli Design Group (retired NYSATE) ressel@frontiernet.net
RICHARD E RICE
Erdman Anthony rricesquash@gmail.com
BRETT ELIASZ, PE
Colliers Engineering
Brett.Eliasz@collierseng.com
KENTON G HINES
Merrill Lynch
Kenton Hines@ml com
KELLY ROBINSON, PE, PHD
Founder, Electrostatic Answers
kelly robinson@electrostaticanswers com
JESSIE COCQUYT
Administrative Director
Builders Exchange of Rochester res@frontiernet.net
First Vice President
DAWN LaPIETRA
L3Harris Corporation
dawnlapietra@gmail.com
Second Vice President
MIKE KURDZIEL, PhD
L3Harris Corporation
mike.kurdziel@L3harris.com
STEVEN W DAY, PhD Rochester Institute of Technology swdeme@rit.edu
NOAH KELLY NAM Products Services Manager, Alstom noah.kelly@alstomgroup.com
JESSICA SHANG, PHD
Associate Professor, University of Rochester j k shang@rochester edu
April First. Thus begins the final 3 months of the program year for RES and many of our affiliates. For starters, April 10th is the Engineering Symposium in Rochester, a face-to-face event that will be held April 10th at the RIT Inn and Convention Center For details and registration, go to the website at https://www.eventleaf.com/e/EngineeringSymposiumRochester. Other events will follow in May and June, so keep an eye on the RES website and newsletter. We will post details of these events as they become available to us. And, as a reminder, if anyone has an event or other announcement, please let us know.
April is also the month that RES traditionally announces Scholarship winners for RES and affiliate scholarships. Congratulations to the eight RES scholarship winners and nine MPES scholarship winners!
Now, on to some RES news: Notice that the magazine is published quarterly, supplanted on the off months by our biweekly newsletter, and further enhanced by our increased social media presence. These changes were instituted to make our communications more accessible, easier to read with content you want and the frequency you need. So far, we seem to be getting it right, but we would like to go beyond “getting it right”; we would like to “get it better”. That’s where you all come in. Let us know what you want to see in our newsletters, social media, website, and magazine
Now, what’s inside the magazine this month:
Lee Loomis gives a rundown of three opportunities for RES members and others interested in volunteering as tutors. These programs provide a vital service to students within the Rochester City School District
Speaking of Lee Loomis, check out his Rochester History article as the walk through the history of Rochester Engineering continues; this month, focusing on activities and events of 1979 Campus News – A sampling of the articles includes research at the University of Rochester and the Rochester Institute of Technology in quantum computing; bringing machine learning to indigenous peoples; the relationship between mechanical signals in cells and viral infections; and bio printing of genetically engineered tissues and organs.
For those who travel the New York State Thruway, be sure to read the article from Hunt Engineers about improvements that have made travel along this vital thoroughfare safer
As always, if you see anything the magazine that interests you, or have any suggestions, please feel free to contact RES at res@frontiernet.net. Thanks again!
Dennis R. Roote, P.E. President, Rochester Engineering Society
RES Tutoring…New Opportunities?!?
With the June 2024 closing of Dr. Walter Cooper Academy (RCSD School #10), the RES has been seeking a new way to support learning in the RCSD.
The RES is NOT interested in forming and managing another tutoring team. Rather, it is the RES’s strong preference to support the recruitment of tutors from area universities, engineering consulting firms and other businesses, to join existing, established tutoring programs, in the Rochester City School District (RCSD).
We have met with the leaders of several local tutoring programs, describing the history of the RES Tutoring Team, to learn if the protocols of their programs are compatible with those of our “veteran” RES Tutors. We have identified three, RCSD K-6 elementary school, in-person, daytime tutoring programs we believe to be compatible with the interests and historic availability of our RES Tutors. The leaders of these programs have shared how they recruit and vet tutors, the academic focus, supervision and parameters of their tutoring programs, and if they would allow “teams” of RES Tutors to alternate their weekly tutoring assignments. Links to each of these programs are provided:
“Help Me Read” - RCSD School #17, 158 Orchard St, Rochester, NY 14611 – Dr David Singleton - Director, Ms. Linda Maulding - Coordinator/Supervisor. School Office: (585) 225-4200. Founded in 2007, this is a program with its own on-site Coordinator, separate office and academic materials storage area. The curriculum support, from the School’s Teacher and Administrators, has been attracting tutors from all around Rochester’s neighborhoods and business community, for almost 20 years. Access information on their program and a tutoring application at: hmrcolc@yahoo.com, “Help Me Read” Coordinator/Supervisor’s phone: (585) 766-8440.
“TRU Impact – Rochester” - RCSD School #16, 321 Post Ave, Rochester, NY 14619 – Victor Norflee – Director. Founded in 2020, this is an established program, led by an experienced RCSD High School Coach and his team, and guided by the School Principal and Community School Site Coordinator. It offers in-person school-day, after school and virtual tutoring. Curriculum includes basic reading, math, science and social studies. Access information on their program and a tutoring application at: www.truimpactroc.org, then go to “contact” page. Inquiries will receive an immediate response from the Director
“Renaissance Academy Charter School of the Arts” - RCSD Charter School, 299 Kirk Rd, Rochester, NY 14612 – Dr Caitlin Loury - Chief Education Officer, Ms. Kilolo Moyo-White – Family Services Coordinator. School Office: (585) 225-4200. Established in 2014, over 90% of the students of this RCSD Charter School reside in the City of Rochester. The additional “arts-focus” in the curriculum of this 500+ student school provides experiences designed to awaken not only the academic, but also the dancing, artistic and musical spirit, in their learners. Access information on their program, and then a tutoring application at: www.renacad.org, https://forms.gle/WqCnkmhjy15yVUHD9
We have begun reaching out to as many of our “veteran” RES Tutors as possible, informing them about these new options, and to inviting them consider volunteering their considerable skills, as experienced tutors, in continued support for RCSD students.
Lee M. Loomis (585) 738-3079 (mobile & text)
CONGRATULATIONS!
TO THE ROCHESTER ENGINEERING SOCIETY’S 2025 SCHOLARSHIP WINNERS
Joesph W. Campbell Memorial
Alex Shuron
Rochester Institute of Technology, Mechanical Engineering
Keith W Amish Memorial Scholarship
Hailey Epstein
University of Rochester, Mechanical Engineering
DHURJATY Family Scholarship
Isabella Doty
University of Rochester, Mechanical Engineering
IEEE
William Knoff
University of Rochester, Electrical and Computer Engineering
David Fergusson Memorial
Darren Chen
University of Rochester, Mechanical Engineering
IEEE
Kyle (Newt) Perlman
University of Rochester, Electrical and Computer Engineering
Adam W. Lawas Scholarship
Mary Cotter
University of Virgina, Mechanical Engineering
Susan L. Costa Memorial Scholarship
Nyasha Gwaza
University of Rochester, Electrical & Computer Engineering
CONGRATULATIONS! TO THE MPES’ 2025 SCHOLARSHIP WINNERS
VASTOLA SCHOLARSHIP
(Sponsored by MPES)
Benjamin Hebrock
Wheatland-Chili High School
Mechanical Engineering
ALSTOM FOUNDATION
SCHOLARSHIP
Blade Surowiec
Wayne High School
Aerospace Engineering
COLLIERS ENGINEERING & DESIGN SCHOLARSHIP
Elizabeth Frick
Wayne High School
ERDMAN ANTHONY SCHOLARSHIP
Erin Hallock
Wheatland-Chili High School
Biomedical Engineering
Civil Engineering
LABELLA FOUNDATION
SCHOLARSHIP
Bria Torpey
Honeoye Falls-Lima High School
RE:BUILD OPTIMATION TECHNOLOGY SCHOLARSHIP
Patrick Ward
Churchville-Chili High School
Chemical Engineering
AMERCIAN COUNCIL OF ENGINEERING COMPANIES SCHOLARSHIP
Anya Bhargava
Victor High School
Biomedical Engineering
EDWARD
RIES
A Sampling from the Archives of the Rochester Engineering Society...1897 - 1978
By Lee M. Loomis
Continuing with the historical sampling of the earlier writings on behalf of the Rochester Engineering Society, the years following "The Great War", into and through the “Great Depression”, continued to be a time of reaching out for the maturing Society, both locally and nationally. The meeting minutes describe a series of technical discussions and presentations intended to broaden the technical horizons of the membership (especially the CE's, ME's and EE's) The RES affiliated itself with a number of National technical societies, adopted local Affiliated Societies, frequently held joint meetings with them and continued taking action on a growing list of public matters Certain issues of standardization, some crucial to public safety, became the responsibility of the RES and its affiliates. In the pervasive economic downturn of the “Great Depression”, the magazine offered classified advertising for unemployed engineers, technicians and draftsmen and took other steps to try to deal with the crisis Still, it continued its effort to shape the function, focus and infrastructure of the City of Rochester, and beyond World War, again affected the Society, taking away many of its leaders while providing opportunities for others to step forward to fill these vacancies In an effort to provide even greater perspective on the happenings and concerns of the day, a synopsis, featuring selected items from "The Rochester Engineer" has become an integral part of this series. The Second World War, the Korean Conflict, and the Vietnam War are now history. These experiences have changed the face of and will, no doubt, influence the future of the community. The Rochester municipal leadership and the industrial community have become immersed in the cold-war, growth economy
“The Rochester Engineer” (February 1979) The January 1979 RES Luncheon meeting was held jointly with the Illuminating Engineering Society (IES) and featured a presentation, “The Partnership of Light and Business”, by Robert T. Dorsey, Manager of Lighting Technology Development, General Electric Co. Mr. Dorsey discussed the relationship of improved lighting levels to productivity, quality of life and reduced operating costs through reductions in business/accounting errors His contention was, “Lighting can be a full-partner with business, contributing increased productivity, greater safety, reduced errors, better work quality and reduced lighting costs ” NY Senator Jacob K Javits was the keynote speaker at the annual Engineers Joint Dinner. Receiving the “1978 Engineer of the Year” award was Dr. Rudolph Kingslake, renowned Professor of Geometrical Optics at the University of Rochester, and retired Director of Optical Design at Eastman Kodak Company. According to the National Science Foundation (NSF), on February 26, 1979, North America would witness its final solar eclipse of the 20th Century The 200 mile-wide, West-to-East total eclipse path, across North America, would begin at the Canadian Province of Manitoba, travel across southern Canada, across Hudson’s Bay, exiting the continent at Quebec and then Greenland. Editor’s Note: The next North American solar eclipse would not occur until 2024.
March 21, 1979 (Board Meeting, University Club) RES Executive Director Joseph Campbell report on RES membership status: Regular Members – 478, Associate Members – 14, Student Members – 9, Junior Members – 33, Non-Resident Members – 23, Honorary Members – 5, Sustaining Members – 19, Retired Members – 3, Total Membership – 629 The Board approved four new applications for Regular Membership It was announced that the RES Annual meeting, May 5, 1979, would be held at the University Club. The NY Water Pollution Association (NYWPA) has asked the RES to co-sponsor a July 1979, one-day seminar on pretreatment regulations and the disposal of toxic sludge. The Board approved, provided that RES Member, Libby Ford, also a member of NYWPA, would deliver opening remarks at this event.
“The Rochester Engineer” (March 1979) The Rochester Chapter of the Illuminating Engineering Society (IES) announced its 1979 Lighting Design Awards, including 1st Place – Wegman’s Food Markets building lobby on Brooks Ave., 2nd PlaceWegman’s Food Markets office area on Brooks Ave., 3rd Place – RG&E Ginna nuclear power plant exterior lighting, Lake Rd , Ontario, NY In his monthly article, “Three for Three ” , RES Technology Agent, Andrew C. Hirsch reflected on this, a third year of energy crises; in 1977 it was the natural gas shortage, in 1978 it was a national coal labor strike, this year (1979) it’s energy supply (primarily gasoline) disruption, due to the fighting in Iran Andy reported that these crises have motivated the City of Rochester and the County of Monroe to focus even more on the impending results of the current energy audits of their respective facilities, by the RES Technology Transfer program contractors. Across the nation, Governments have increased their attention to the relentless rising cost(s) of energy According to TV network news, recent gasoline rationing has only resulted in motivating motorists to keep their tanks 50% fuller than before, to avoid “running out of gas”, merely exacerbating the situation
April 18, 1979 (Board Meeting, University Club) Following a detailed discussion of across-the-board rising costs for operating the RES, the Board approved changes (increases) in annual dues, as follows: Regular Membership - $35, Associate Membership - $35, Emeritus Membership - $5, Student Membership - $5 Plans were announced for a Fall 1979 joint RES-Society of Motion picture & Television Engineers (SMPTE) dinner meeting, at the University Club, followed by a tour of Channel 10’s new facilities on East Ave.
“The Rochester Engineer” (April 1979) It was announced that RES member, Lynne Bellenger, PE, has been selected as “Young Engineer of the Year” by the NY State Society of Professional Engineers The RES Board announced that former Rochester City Manager, Eli Freedman, has been named an Honorary Member It was announced that RES Member, Ernest Mohr, Assistant Manager of the Facilities Organization, Kodak Park, would speak on, “Environmental Decisions that will shape our Future”, at the April 11, 1979, RES Luncheon, at the Colonial Inn, Empire Blvd. (roast beef plate $3.95).
Subsequent articles in this series will describe the RES' continuing outreach to other technical societies as it considered its role in this and the larger community It will feature more of the activities of the RES as it moved to be of greater service to its membership, as the Society adopted a greater role in shaping the future of the City and its environs Noted also, will be the contributions made by RES members in the struggle to meet the challenges coming out of World War II, the Korean Conflict and the Vietnam War, as well as a hoped-for period of post-war growth and prosperity. These articles will also feature an impressive array of RES activities in support of post-war re-emergence of Rochester area industry, and the continuing prosperity of the second-half of the 20th Century
We welcome your questions and comments on this series
Twisting atomically thin materials could advance quantum computers
Luke Auburn | Director of Communications, Hajim School of Engineering & Applied Sciences March 15, 2025
Placing two layers of special 2D materials together and turning them at large angles creates artificial atoms with intriguing optical properties.
Bytakingtwoflakesofspecialmaterialsthatarejustoneatomthickandtwistingthemathighangles,researchersattheUniversityof Rochesterhaveunlockeduniqueopticalpropertiesthatcouldbeusedinquantumcomputersandotherquantumtechnologies Ina newstudypublishedinNanoLetters,theresearchersshowthatpreciselylayeringnano-thinmaterialscreatesexcitons essentially, artificialatoms thatcanactasquantuminformationbits,orqubits.
Graduate student Trevor Ollis fills a camera with liquid nitrogen to cool it to -120 degrees Celsius in order to examine monolayer materials developed in the laboratory of Nickolas Vamivakas. (University of Rochester photo / J. Adam Fenster)
Twisting atomically thin materials could advance quantum computers
Luke Auburn | Director of Communications, Hajim School of Engineering & Applied Sciences
Vamivakas and his fellow researchers place monolayer materials in chips that are cooled through a cryostat to observe their unique optical properties. (University of Rochester photo / J. Adam Fenster)
NewtechnologycouldquashQRcode phishingattacks
Luke Auburn | Director of Communications, Hajim School of Engineering & Applied Sciences February11,2025
The improved QR code format would let smartphone users know if they’re heading to a secure website—or wading into a potential ‘quishing’ scam.
Professors Karin Wuertz-Kozak, left, and Maureen Ferran will be working on a new research project to explore how mechanical forces influence viral infection rates in the lungs to reduce disease progression
Photo credit: Scott Hamilton/RIT
Researchers explore how mechanical signals influence viral infections in lungs
New work brings together an under-studied area of mechanical signals on cells and their influence on viral infections by Michelle Cometa | February 24, 2025
CRISPR Genomic Engineering as a Tool to Develop Functional 3D
Bioprinted
Models.
By Iker Martinez Zalbidea, PhD Student, RIT.
3D bioprinting represents a revolutionary advancement in medical technology that offers many innovative approaches to healthcare and biomedical research. These include the development of personalized implants and prosthetics, functional human organs for transplantation, or development of customized disease treatment models for research purposes [1, 2, 3]. Another innovative development is CRISPR-Cas9 technology, a geneediting tool that allows for precise modifications of the genome [4]. The integration of CRISPR-Cas9 genomic engineering and 3D bioprinting will revolutionize the fields of regenerative medicine, tissue engineering, and drug development
Applications:
By CRISPR editing the cells used in 3D bioprinting, it is possible to improve tissue properties, correct genetic defects, and introduce new functionalities that may not be present in natural tissues. Several key applications of CRISPR in 3D bioprinting-based medicine include:
Engineering Functional Tissues
CRISPR technology can be used to edit the genes of the cells used in bioprinting to enhance their ability to form functional structures, such as blood vessels, cartilage, or nerve tissue In this regard, CRISPR can be used to induce the expression of genes that promote the formation of blood vessels, tissue regeneration, or stem cell differentiation.
Gene
Therapy and Disease Modeling By editing the genomes of cells used in 3D
bioprinting, researchers can create personalized models of diseases such as cystic fibrosis, muscular dystrophy, or specific cancer types. These models can be used to study disease mechanisms, test new drug candidates, and develop personalized therapeutic strategies. In this way, CRISPR-edited bioprinted tissues can serve as powerful tools for preclinical drug testing, reducing the reliance on animal models and enabling more accurate predictions of human responses to treatments [5, 6]. Personalized Medicine The use of patient-specific data in both
CRISPR and 3D bioprinting can result in personalized therapies for each patient. For example, CRISPR can be used to correct genetic mutations in a patient’s own cells, which are then bioprinted to create autocompatible tissues. These bioprinted tissues can be used for transplantation (including animal organ xenotransplantation), reducing the risk of immune rejection and improving the success rate of grafts [5, 6, 7].
Enhanced Stem Cell Therapy
CRISPR can be employed to improve the differentiation of stem cells into specific cell types needed for 3D bioprinted tissues. In this way, CRISPR-edited stem cells can be used to create more functional and stable tissues for therapeutic applications, such as cartilage regeneration or bone repair [8].
Drug Testing and Toxicity Screening
By incorporating genetically modified cells into tissue constructs, researchers can mimic human disease states and screen drugs for efficacy and safety. This is particularly important in the early stages of drug development, where traditional 2D cell cultures and animal models often fail to accurately predict human responses.
For instance, bioprinted tissues with CRISPR-edited liver and other cells types have been used to screen for the toxic effects of pharmaceutical compounds, enabling more accurate predictions of drug safety [9, 10]. Another example are 3D printed glioblastoma models (printed with tissue derived gelatin bioink) for drug screening using CRISPR [5].
Figure 2 General 3D bioprinting applications and cell types that can be used to emulate different organs [11].
Process The process of developing a genetically modified cell line, and using them in a 3D bioprinted tissue involves several crucial steps:
- Cell isolation and expansion: Depending on the goal, different cell types can be used. For example, induced Pluripotent Stem Cells (iPSCs) can be differentiated into different cell types (such as liver or heart muscle tissue), and can be obtained from pre-existing repositories, or generated from individual patients using genetic reprogramming [12].
CRISPR target design: The first step before genetically modifying cells is designing the guide RNA targeting the gene of interest. For the most common CRISPR-Cas9 applications the goal is to target the protein coding regions of a gene. In other applications, the gRNA is aimed at regulatory regions, such as gene promoters For example, CRISPR-Cas9 can be used to “knock-out” (disable) a gene an induce a disease phenotype, which can then be studied in a 3D model.
CRISPR Delivery: The entire CRISPR system (which includes Cas9 and guide RNA) is delivered into the cells Delivery methods include viral vectors and lipofection 3D bioprinting: The 3D scaffold should have pores for nutrient and waste exchange to support cell survival, and should be composed of biodegradable materials like
hydrogels, alginate, or collagen, that allow the cells to adhere and proliferate. The bioprinter should be capable of printing at a cellular resolution, like an extrusionbased or inkjet-based bioprinter, while simultaneously avoiding damaging the cells. The modified cells will then be mixed with bioinks containing growth factors and nutrients, and the printed into the pre-designed 3D structure. Each layer of cells is printed to build the tissue, with precision to mimic the natural structure. Post-printing culture: After the printing process, the cells need to be maintained into the appropriate conditions, which might require differentiating the cells into the desired tissue type. A complex 3D organ will likewise require the proper maturation of the cells and vascularization -
After this process, the 3D tissue would be ready for its intended use. That might require surgery or in vitro experiments.
Figure 3 The basic process of gene editing cells before infusing the cells in a 3D printable bioink. (Created with BioRender.com).
Despite the newest advancements, there are numerous challenges to address before these technologies can be fully integrated and applied to general healthcare applications.
- Off-Target Effects: Even though CRISPR is precise, it can sometimes make unintended changes in other parts of the DNA, which could be a serious problem edit the wrong part of the genome when applied to a patient.
- Long-term genetic stability: The introduced genetic modification could negatively affect the cells in unexpected ways in the long term, or the desired changes could perhaps not remain stable.
- Retaining cell viability and function: Cells can be damaged by the printing process due to mechanical stress, temperature variations, or exposure to UV light. Ensuring that printed cells remain healthy and functional after printing is critical for successful tissue engineering.
- Ethical and Regulatory Issues: genetic modification and bioprinting of human tissues and organs raises ethical concerns, such as the use of stem cells, or the implications of creating tissues or organs that are genetically modified. In conclusion, by enabling the development of personalized tissue models, diseasespecific constructs, and more functional tissues, CRISPR-enhanced 3D bioprinting could lead to significant advancements in the treatment of genetic disorders, the creation of organ models for drug testing, and the generation of personalized therapies for patients. As these technologies continue to evolve, the synergy between CRISPR and 3D bioprinting will likely play a pivotal role in shaping the future of medicine
References
[1] Fang W, Yang M, Wang L, Li W, Liu M, Jin Y, Wang Y, Yang R, Wang Y, Zhang K, Fu Q. Hydrogels for 3D bioprinting in tissue engineering and regenerative medicine: Current progress and challenges. Int J Bioprint. 2023 May 23;9(5):759. doi: 10.18063/ijb.759. PMID: 37457925; PMCID: PMC10339415.
[2] Lam EHY, Yu F, Zhu S, Wang Z. 3D Bioprinting for Next-Generation Personalized Medicine. Int J Mol Sci. 2023 Mar 28;24(7):6357. doi: 10.3390/ijms24076357. PMID: 37047328; PMCID: PMC10094501.
[3] Murphy, S., Atala, A. 3D bioprinting of tissues and organs. Nat Biotechnol 32, 773–785 (2014). https://doi.org/10.1038/nbt.2958
[4] Doudna, J. A., & Charpentier, E. (2014). "The new frontier of genome engineering with CRISPR-Cas9." Science, 346(6213), 1258096.
[5] Tang, M., Xie, Q., Gimple, R.C. et al. Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. Cell Res 30, 833–853 (2020). https://doi.org/10.1038/s41422-020-0338-1
[6] Gopal S, Rodrigues AL and Dordick JS (2020) Exploiting CRISPR Cas9 in ThreeDimensional Stem Cell Cultures to Model Disease. Front. Bioeng. Biotechnol. 8:692. doi: 10.3389/fbioe.2020.00692
[7] Li P, Zhang W, Smith LJ, Ayares D, Cooper DKC, Ekser B. The potential role of 3Dbioprinting in xenotransplantation. Curr Opin Organ Transplant. 2019 Oct;24(5):547-554. doi: 10.1097/MOT.0000000000000684. PMID: 31385888; PMCID: PMC6861853.
[8] Li C, Du Y, Zhang T, Wang H, Hou Z, Zhang Y, Cui W, Chen W. "Genetic scissors" CRISPR/Cas9 genome editing cutting-edge biocarrier technology for bone and cartilage repair. Bioact Mater. 2022 Oct 7;22:254-273. doi: 10.1016/j.bioactmat.2022.09.026. PMID: 36263098; PMCID: PMC9554751.
[9] Xu T, Li L, Liu YC, Cao W, Chen JS, Hu S, Liu Y, Li LY, Zhou H, Meng XM, Huang C, Zhang
L, Li J, Zhou H. CRISPR/Cas9-related technologies in liver diseases: from feasibility to future diversity. Int J Biol Sci. 2020 Jun 1;16(13):2283-2295. doi: 10.7150/ijbs.33481. PMID: 32760197; PMCID: PMC7378651.
[10] Hendriks, D., Brouwers, J.F., Hamer, K. et al. Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis. Nat Biotechnol 41, 1567–1581 (2023). https://doi.org/10.1038/s41587-023-01680-4
N. 3D bioprinting using stem cells. Pediatr Res. 2018 Jan;83(1-2):223-231. doi: 10.1038/pr.2017.252. Epub 2017 Nov 1. PMID: 28985202.
[12] Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007 Nov 30;131(5):861-72. doi: 10.1016/j.cell.2007.11.019. PMID: 18035408.
It Might Feel Wild & Wooly
Thruway Has Been Getting Safer for Decades
Advances in Car Technology and Transportation Engineering Lead the Way
Written by: Barry J. Dumbauld, PE, and Mark Pawloski, PE, Hunt E|A|S
Introduction
With thousands and thousands of New York State Thruway miles under our belts -- including now weekly cross-state trips to either Buffalo or Burlington, VT, HUNT-EAS’ co-authors have enormous “street cred” when describing the scenario that originally set our research question in motion.
“How is it possible”, we regularly wondered, “that there aren’t countless multiple-car accidents along the Thruway daily?”.
They travel in packs of seven…eight…nine…You’ve all seen them, experienced them, or maybe even gotten caught up in their riptide.
Eighty-plus miles-per-hour and at most five yards apart, a tightly bound group of SUV’s and cars roar up, impatiently flashing their headlights Autobahn-style as you attempt to pass an 18-wheeler or a 1972 Pinto. On otherwise lonely stretches, they look like a snake wiggling away in the distance. But throw in a dawdling RV, a horse trailer, and a modest family station wagon, and we’ve all had the same thought, “One false move and cars are going to start bouncing”!
But somehow it doesn’t seem to happen. In fact, NYSTA officials can proudly boast that their 570-mile responsibility is “statistically safer than many other roadways” with a “lower fatality rate…significantly lower…when compared to the national averages reported by the U.S. Department of Transportation”.
Still, how is this possible?
Like expecting to see the Porsche that blew by at 90MPH pulled over by a Trooper, for years we worried that whatever cosmic magic keeping these high-speed cars separated by inches was tenuous at best and around the corner a pile-up awaited us. However, more recently we’ve settled on a different theory – the successes of modern car technology and transportation engineering.
The Thruway as an Example
According to the NYSTA, Thruway customers regularly travel over 7 billion vehicle-miles annually on the highway, averaging more than 21.2 million vehicle-miles per day. At 570 miles in length, the NYS Thruway is one of the largest tolled highway systems in the United States and is a critical component of the national interstate network. Since 1960, the Thruway has seen an improvement in the reduction of fatal car crashes of 78%, dropping from 5.2 per 100 Million miles traveled to 1.1 in 2019!
It Might Feel Wild & Wooly (particularly on Bill’s game
But the Thruway Has Been Getting Safer for Decades
Advances in Car Technology and Transportation Engineering Lead the Way
Written by: Barry J. Dumbauld, PE, and Mark Pawloski, PE, Hunt E|A|S
There are few alternatives to the Thruway as it connects the principal cities of the State from New York City to Albany, and on to Utica, Syracuse and Rochester through to Buffalo and the Pennsylvania state line.
The Thruway corridor serves 37 of the State’s 62 counties and the majority of the State’s population. According to Thruway authorities, approximately 400 million toll transactions occur annually, generating over $800 million in toll revenues.
Where Do Most Crash Deaths Occur in NY?
The upstate region’s highest fatality totals were in Erie County (59 in 2022), Monroe County (45) and Orange County (39). Downstate counties saw fewer fatal accidents — including Westchester (36), Dutchess (26) and Rockland (20).
Click on photo to watch video
Most fatalities took place on New York’s urban roadways, an increase of nearly 70% since 2017. While Long Island’s two-county total of 245 fatalities led the state, the North Country region had the highest per capita rate at nearly 13 deaths for every 100,000 people.
The Main Causes
In 2023, 5,111 police-reported crashes in New York State involved “fatigue/drowsy driving” and/or “driver fell asleep” as contributing factors, according to preliminary statistics from the Institute for Traffic Safety Management and Research (ITSMR) at the University at Albany’s Rockefeller College.
In 2022, according to the National Highway Traffic Safety Administration (NHTSA), there were 693 fatalities from drowsy-driving-related crashes in the United States. NHTSA also estimates that 100,000 crashes each year are caused primarily by drowsy driving, resulting in more than 71,000 injuries. The AAA Foundation for Traffic Safety also cites drowsy driving as the cause of thousands of car crashes each year, killing an estimated 6,400 people nationally
Analyzing car safety trends in New York State over the last decade reveals a complex picture, with the State witnessing a surge in motor vehicle fatalities post-2019, reversing previous safety gains. This spike, mirroring a national trend, is particularly pronounced in New York and is attributed to pandemic-induced changes in driver behavior, notably increased speeding and reckless driving. Fatalities reached a decade high in 2022. Distracted driving, particularly from cell phones and in-vehicle systems, remains a primary cause of crash. Contributing factors to fatalities also include driving under the influence, failure to obey traffic laws, and pedestrian/bicyclist errors. Furthermore, fatality rates exhibit demographic variations, with higher rates among males and older age groups.
The recent rise in fatalities highlights the urgent need for sustained efforts to promote safe driving practices, rigorously enforce traffic laws, and enhance road safety infrastructure to mitigate these alarming trends.
It Might Feel Wild & Wooly (particularly on Bill’s game days), But the Thruway Has Been Getting Safer for Decades
Advances in Car Technology and Transportation Engineering Lead the Way
Written by: Barry J. Dumbauld, PE, and Mark Pawloski, PE, Hunt E|A|S
Law Enforcement
Law enforcement plays a pivotal role in maintaining safety on the New York State Thruway. Increased patrols and stringent enforcement of traffic laws, including speeding, DUI, and distracted driving, are essential deterrents Specifically, the "Move Over Law" requires strict enforcement to protect emergency responders and maintenance workers Technological advancements, such as traffic monitoring systems and driver alert technologies, bolster these efforts. Public awareness campaigns are also critical, educating drivers about safe practices and the dangers of risky behaviors. The Thruway's unique high-speed environment necessitates a focused approach, with particular attention to the normalization of increasingly high average speeds and their impact on the number and severity of accident rates, as well as the persistent problem of impaired and distracted driving.
Law enforcement utilizes advanced technologies like radar, lidar, and impaired driving detection systems, while commercial vehicle enforcement employs over-height detection systems to prevent bridge strikes.
The post-COVID surge in risky driving behaviors, including increased speeding and reduced seatbelt use, has further complicated safety efforts, necessitating continued rigorous law enforcement and public awareness campaigns to address these ongoing concerns
Despite these efforts, accidents still occur, often exacerbated by factors unique to the Thruway Distracted driving, including cell phone usage and in-vehicle distractions, remains a persistent challenge, particularly on long stretches of highway. Impaired driving continues to be a serious issue, with regular DUI arrests. Furthermore, New York's diverse weather conditions, including snow, ice, rain, and fog, pose significant safety hazards.
Car Technology & Transportation Engineering Propel Significant Safety Advances
For a lot of our HUNT colleagues, it’s hard to imagine a time before seatbelts, airbags, and highly engineered tires, let alone cruise control. Describing highways littered with cars pulled over…steaming radiators and flat tires, elicits disbelieving “yeh yehs” Pick-up trucks with kids rolling around in the back bed and families of seven crammed into a VW bug were not uncommon (ask my wife!).
It was with that premise in mind that our HUNT colleague Mark Pawlowski, PE began the following litany of automotive technological advances: “Automotive technology is revolutionizing road safety through the integration of Advanced Driver-Assistance Systems (ADAS) Features like blind-spot detection, lane departure warning, and adaptive cruise control use sensors, cameras, and radar to provide real-time information and assistance, significantly reducing collisions and improving traffic flow.”
The list continues with forward-collision warning, and automatic emergency braking (AEB) which can prevent or mitigate crashes, particularly rear-end collisions Adaptive headlights enhance visibility, and rearview cameras eliminate blind spots during reversing. Electronic Stability Control (ESC) has proven effective in reducing singlevehicle crashes.
It Might Feel Wild & Wooly
(particularly on Bill’s game days),
But the Thruway Has Been Getting Safer for Decades
Advances in Car Technology and Transportation Engineering Lead the Way
Written by: Barry J. Dumbauld, PE, and Mark Pawloski, PE, Hunt E|A|S
Furthermore, mobile applications and virtual driving simulators are enhancing road safety awareness and education, while AI-powered models analyze data to identify high-risk areas and proactively warn drivers.
While these technological advances promise a safer future, HUNT’s Director of Transportation, Barry Dumbauld, PE agreed that it is crucial to address potential challenges. Overreliance on technology and distractions from “infotainment” systems and cell phones can undermine safety Drivers must be thoroughly trained on the effective use and limitations of these technologies to maintain situational awareness.
Transportation Engineering:
Fresh from the design of a curb-cut, road-dieting effort in the Village of Honeoye Falls, Barry was glad to engage in our research on other transportation engineering advances, asserting that his team and others were “significantly enhancing road safety through smart infrastructure and improved road design ”
Intelligent Transportation Systems (ITS) utilize sensors, cameras, and data analytics to optimize traffic flow, featuring smart traffic signals, variable message signs, and roadway sensors for real-time monitoring and incident response. Simultaneously, transportation engineers are implementing safer highway designs, including roundabouts to reduce intersection crash severity, cable guide-rail barriers and box-beam rails to prevent headon collisions, and enhanced lighting and signage for improved visibility. Data analytics further bolster these efforts by identifying high-risk areas and enabling predictive analytics and efficient incident management, ultimately contributing to safer roadways
The NYSTA is at the forefront of integrating technological advancements into its infrastructure Sophisticated traffic management systems provide real-time monitoring of traffic flow, weather conditions, and incidents, while variable message signs offer drivers crucial, up-to-the-minute information. Infrastructure improvements include enhanced pavement markings, advanced lighting, and technologies aiding winter maintenance The integration of vehicle technologies, such as ADAS, and the increasing use of data and monitoring systems, including unmanned aerial systems (UAS), further contribute to a safer Thruway environment The implementation of electronic tolling has also helped to reduce congestion, improving overall safety.
Drive Safe, and Go Bills!
Analyzing car safety trends in the Rochester, NY region reveals a situation with some unique local characteristics, while also reflecting broader state and national trends. Here's a summary courtesy of Rochester PD and the Rochester Beacon:
Key Trends and Concerns:
Increased Pedestrian and Cyclist Vulnerability:
A significant concern in Rochester is the high rate of pedestrian and cyclist injuries and fatalities. This has led to increased focus on improving street safety for non-vehicle users.
Senator Schumer has highlighted that Rochester has among the highest rates of fatalities per crash of any midsize city in New York State, particularly concerning pedestrian and cyclist safety.
This has resulted in efforts to obtain funding for infrastructure improvements like dedicated bike lanes, improved crosswalks, and better lighting.
Motor Vehicle Thefts:
Rochester has experienced a notable surge in motor vehicle thefts, particularly in recent years. This trend has placed added emphasis on vehicle security and crime prevention.
General Traffic Safety:
Like other areas, Rochester faces ongoing challenges related to: Distracted driving
Speeding
Impaired driving
Infrastructure Impact:
The condition of roads in the Rochester region plays a role in safety. Deteriorated roads and congestion contribute to increased vehicle operating costs and crash risks.
In summary: The Rochester region is addressing a combination of general traffic safety concerns and specific local challenges, such as the high vulnerability of pedestrians and cyclists and rising motor vehicle thefts. There is a strong push for infrastructure improvements and increased safety measures to mitigate these risks.
How do roundabouts affect safety?
Several features of roundabouts promote safety. At traditional intersections with stop signs or traffic signals, some of the most common types of crashes are right-angle, left-turn, and head-on collisions. These types of collisions can be severe because vehicles may be traveling through the intersection at high speeds. With roundabouts, these types of potentially serious crashes essentially are eliminated because vehicles travel in the same direction.
Installing roundabouts in place of traffic signals can also reduce the likelihood of rear-end crashes and their severity by removing the incentive for drivers to speed up as they approach green lights and by reducing abrupt stops at red lights. The vehicle-to-vehicle conflicts that occur at roundabouts generally involve a vehicle merging into the circular roadway, with both vehicles traveling at low speeds generally less than 20 mph in urban areas and less than 30-35 mph in rural areas.
A 2001 Institute study of 23 intersections in the United States reported that converting intersections from traffic signals or stop signs to roundabouts reduced injury crashes by 80 percent and all crashes by 40 percent. Similar results were reported by Eisenman et al.: a 75 percent decrease in injury crashes and a 37 percent decrease in total crashes at 35 intersections that were converted from traffic signals to roundabouts
Two studies of intersections in Europe and Australia that were converted to roundabouts have reported 41-61 percent reductions in injury crashes and 45-75 percent reductions in severe injury crashes.
About the Authors
Barry J. Dumbauld, PE, and Mark Pawloski, PE have more than 50 years of combined Transportation Design and Department of Transportation (DOT) engineering experience Sean M Phelan, Associate AIA, has worked on Main Street and urban economic development projects for more than 25 years. HUNT-EAS provides a broad range of transportation engineering services, including roadway and bridge design, highway and interchange design, construction administration, construction inspection, and project management.
HUNT’s Transportation Services include: site-specific work on State & Interstate Highways, Interchanges, County & Town/City Roads, Urban Streets & Streetscapes, and Bridges. Those efforts are led by Traffic Studies, Horizontal Curve Studies, Survey & Mapping, Hydrologic & Hydraulic Studies, Construction Inspection, Construction Administration, and Stormwater Management Our Safety-First emphasis sees our team assisting with Pedestrian & Bicycle Paths, Traffic Signals, Traffic Calming, ADA Pedestrian Accommodations, Complete Streets, and Safe-to School programs for our K-12 clients
To get the most up to date and detailed information, we recommend checking these resources:
New York State Department of Motor Vehicles (DMV)
New York State Department of Health
National Highway Traffic Safety Administration (NHTSA)
New York State Comptroller's office.
NYSDOT & NYSTA
ASHRAE Family & Friends,
As we dig our way out of winter, I reflect on our chapter's program and the wonderful support we have received this year. We sincerely thank all our members for attending and participating in our chapter programs Your presence and engagement are what make these events successful and enriching for everyone involved, which helps foster a vibrant and collaborative community. We look forward to seeing you at future events and continuing to share valuable experiences together. Thank you for being an integral part of our chapter!
Last month, our March Chapter meeting featured an insightful presentation on Ventilation, Filtration, and Clean Airflow by Daryl DeAngelis from EBTRON His engaging talk highlighted the significant impact these topics have on our built environment The event was themed as our "Past Presidents Luncheon," and we were fortunate to have thirteen of our Chapter's past presidents in attendance. As we celebrate our Chapter's 70th Anniversary in 2025, this provided a wonderful opportunity to recognize our past leadership for their invaluable contributions to both ASHRAE and our Chapter's success over the years
Our next meeting is scheduled for Monday, April 14th. We will explore local large-scale refrigeration systems currently in operation at the Wegmans Distribution Center. The event will feature a dinner presentation on these systems, followed by a site tour of the facility. While the dinner and presentation are open to all, please note that there are limited spots available for the tour, so early registration is encouraged A big thank you to Wegmans Food Markets and Meier Supply Co for making this event possible!
Our Sustainability Committee will be hosting a community event on Friday, April 18th where our group will participate in an Energy Treasure Hunt at the Browncroft Community Church in Penfield. During this event, participants will team up to search for energy-saving opportunities while touring the facility. This will be a fantastic opportunity for networking with industry colleagues and learning more about energy-saving strategies.
Back by popular demand, ASHRAE Rochester's Annual Golf Outing and Picnic will be held on Tuesday, May 20th at Ravenwood in Victor. Mark your calendars! Keep an eye out for details on tickets and sponsorship opportunities to support this popular event, which tends to sell out quickly!
We extend our heartfelt gratitude to everyone who donates to ASHRAE Research Promotion (RP). Your contributions help fund a wide range of programs supported by ASHRAE, including scholarships, numerous research projects, and the development of essential technical guidelines, standards, and handbooks. If you are interested in becoming a donor and supporting these initiatives, please reach out to our RP committee chairperson, Dan Diaz (Dan.Diaz@tranetechnologies.com) for more information on how you can contribute to this great cause.
Bret Fryover, PE
ASHRAE Rochester Chapter President, 2024-2025
Thanks to our Past Presidents for paving the way!
April 2025 Newsletter
Officers & Societies
CHAIR
Kelly Robinson
VICE-CHAIR
Emmett Ientilucci
TREASURER
Lyle Tague
SECRETARY
Eric Zeise
AES & COMSOC
Cristiano Tapparello
CS & CIS
Bo Yuan
EDS & CSS
Sean Rommel EMBS
Cristian Linte GRSS
Emmett Ientilucci
LIFE
Jean Kendrick
APS & MTTS
Danielle Walters
PHOTONICS
Parsian K Mohseni
PES & IAS
Kelly Robinson
Jean Kendrick
SPS
Eric Zeise
TEMS
Paul Lee
YOUNG PROF
Eric Brown
STUDENT CHAP.
Univ. of Rochester
Ming-Lun Lee
RIT
Jamison Heard
AWARDS
Jean Kendrick
COMMUNICATION
Christine Frayda
Howard Bussey
NEWSLETTER
Mark Schrader
PACE
Bruce Rubin
HISTORIAN
Ram Dhurjaty
CS/CIS
RES LIASON
Greg Gdowski
Satellite Remote Sensing for National Security
was presented by Dr. S. Didi Kuo, the Chief Geospatial Intelligence Systems Acquisition Directorate Architect at the National Reconnaissance Office. He discussed the various roles that satellite remote sensing plays in national security and how his degree from the Center for Imaging Science at RIT has prepared him for his career and work.
Bio:
Dr. S. Didi Kuo, a member of the Defense Intelligence Senior Executive Service, is the Principal Deputy Director, Geospatial Intelligence Systems Acquisition (GEOINT) Directorate for the National Reconnaissance Office (NRO). Dr. Kuo leads a joint team responsible for the planning, cross-coordination, and acquisition of systems that provide critical space-based GEOINT data to national decision makers and warfighters worldwide. He has experience in research and development, program management, and architectural analysis with both the Department of Defense and Intelligence Community.
Dr. Kuo is a distinguished graduate of the U.S. Air Force Academy with a degree in physics Over his 26 years in the U S Air Force he served with the Air Force Research Laboratory, the Air Force Maui Optical Station, the Space and Missile Center, and the Air Staff at the Pentagon His last assignment was as a Senior Materiel Leader at the NRO, retiring from the Air Force at the rank of Colonel. Dr. Kuo then joined the NRO Cadre and served as the GEOINT Chief Architect prior to becoming the Principal Deputy Director
Dr. Kuo has a Ph.D. in Imaging Science from the Rochester Institute of Technology and is a graduate of the Air
Command and Staff College and the Industrial College of the Armed Forces
Reported by Dr. Emmett J. Ientilucci (Emmett@cis.rit.edu)
Gerald W Harris Endowed Professor, Graduate Admissions Chair IEEE Region 1 Western Area Chair, IEEE Rochester Section Vice Chair Geoscience & Remote Sensing Society Western NY Chair, Digital Imaging and Remote Sensing Laboratory, Chester F. Carlson Center for Imaging Science
Affiliated Societies of the Rochester Engineering Society
American Consulting Engineering, Companies of New York
American Public Works Association Monroe County/Genesee Valley Branch
American Society of Civil Engineers, Rochester Section
American Society of Heating, Refrigerating, and Air-Conditioning Engineers, Rochester Chapter
American Society of Mechanical Engineers, Rochester Section
American Society of Plumbing Engineers, Rochester NY Chapter
Electrical Association
Genesee Valley Land Surveyors Association
Illuminating Engineering Society of North America Inc., Rochester Section
Imaging Science & Technology, Rochester Chapter
Institute of Electrical and Electronics Engineers, Rochester Section
Institute of Industrial and Systems Engineers, Rochester Chapter
Monroe Professional Engineers Society
New York State Association of Transportation Engineers, Section 4
Rochester Plant Engineers
Association for Bridge Construction and Design
Society of Plastics Engineers, Rochester Section
Terra Rochester Finger Lakes Science & Engineering Fair