Re-acxel

AUTHORIZED DISTRIBUTOR OF STC NARA CO., LTD

Re-Acxel

RE-ACXEL SKIN R E-VITAL SYSTEM N O PR ESERVATIVES. NO COLORING. NO PERFUME Re-Acxel Skin Re-Vital System contains growth factors such as EGF(Epidermal Growth Factor), KGF(Keratinocyte Growth Factor), and PDGF (Platelet Derived Growth Factor) that promote skin tissue repair and regeneration.

Re-Acxel S K I N RE-V ITAL SYSTEM

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C ONTENT S

01. ABO U T TH E P RO D UCT 02. BENEFI TS AND EFFECTS 03. HOW TO AP P LY 04. PROD U CT D EVELO P M ENT 05. MAN U FACTURI NG P L ANT

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01

AB O U T T H E P RO D U CT

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H IG H- P E RFOR MA NCE AM P O U L E that restores skin stem cells

The human-stem-cell-conditioned media (STC-HSCM) anti-aging ampoule has the stem cell growth factors which are generated in the process of cultivating the stem cells, and restores the function of damaged skin.

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01

A B OU T T H E PRODU CT

The skin and its structure: The skin has three main layers - the epidermis, dermis and subcutis. The epidermis contains layers of cells called keratinocytes. BL = basal layer; SL = spinous layer; GL = granular layer; SC= stratum corneum.

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ST EM C E LL COSMET I CS CO N TA I N VA RI O US G ROW TH FA CTOR S , NOT L I V E ST EM C ELLS Skin tissue is a very important tissue in our bodies. It protects us from infection and dehydration, and allows us to feel many different things, such as pressure or heat. Our skin has to be constantly renewed throughout our lives. It relies on a whole host of different stem cells to keep it in good shape.

In everyday life your skin has to cope with a lot of wear and tear. For example, it is exposed to chemicals like soap and to physical stresses such as friction with your clothes or exposure to sunlight. The epidermis and skin appendages need to be renewed constantly to keep your skin in good condition. What’s more, if you cut or damage your skin, it has to be able to repair itself efficiently to keep doing its job - protecting your body from the outside world. Skin stem cells make all this possible.

They are responsible for constant renewal of your skin, and for healing wounds.

So far, scientists have identified several different types of skin stem cell, that one of them is Epidermal stem cells. Epidermal stem cells are responsible for everyday regeneration of the different layers of the epidermis. These stem cells are found in the basal layer (BL) of the epidermis.

Re-Acxel contains numerous stem cell growth factors such as EGF (Epidermal Growth Factor), KGF (Keratinocyte Growth Factor), and more. Growth factors stimulate biochemical pathways that promote skin tissue repair and regeneration.

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02

BE NE FI TS & EFFECTS

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What are G ROW TH FA CTOR S ?

About 250 types of growth factors are produced in the process of cultivating the stem cells. The stem cell growth factor is a collective term for the polypeptides that stimulate the segmentation, growth, and differentiation of various cells.

INCORPORATION OF STEM-CELL-STIMULATIVE AGENT

PROLIFERATION OF FIBROBLAST

SYNTHESIS OF COLLAGEN AND ELASTIN

ACCELERATION OF SKIN REGENERATION, WRINKLE REDUCTION AND ELASTICITY PROMOTION

The skin stem cells are activated through the insertion of stemcell-stimulative agents into the stem cells in the skin. They are then differentiated and proliferated into various cells, including the fibroblasts, which accelerate the synthesis of collagen and elastin fiber to recover the skin’s normal tone and to make the skin healthy and beautiful by smoothing the wrinkles and normalizing the abnormal melanocytes.

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02

BE NE FI TS & EFFECTS

Wrinkle reduction rate before and after using the product (%):

10.00

8.76%

8.00 6.00

4.74%

4.17%

4.03%

4.00 2.00 0.00

Celgen

Improvement rate (%)

Our product R Company’s product

After 4 weeks

Wrinkle reduction compared to before using the product

www.ellead.com Testing Period: 03 Dec 2008 - 12 Feb 2009

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After 8 weeks

Superb wrinkle reduction effect of

M A RV E LO US SKI N R E-V I TA L SYST EM

· “Stem-cell-activating component” (No. 1-60-2008-8257) registered in International Cosmetic Ingredient Dictionary (ICID) · Its wrinkle reduction effect and safety have been proven at the one and only clinical agency designated by the Ministry of Food and Drug Safety in South Korea and abroad. · 8.76% wrinkle reduction effect after 8 weeks of using the product.

GLS (Initial of Tester’s Name) · 8 weeks · 0 week

PIJ (Initial of Tester’s Name) · 0 week · 8 weeks

KCH (Initial of Tester’s Name) · 0 week · 8 weeks

UMH (Initial of Tester’s Name) · 8 weeks · 0 week

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02

BE NE FI TS & EFFECTS

Re-Acxel Improves skin elasticity through collagen-elastin synthesis

Restores clear and clean skin through the normalization of the melanocytes

Powerful regeneration effect for damaged skin

Enhanced moisturizing effect for dry skin

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Main Ingredients of

MA RV E LO US SKI N R E-V I TAL SYST EM Multiple Growth Factors such as EGF (Epidermal Growth Factor) , PDGF (Platelet Derived Growth Factor) , HGF (Hepatocyte Growth Factor), KGF (Keratinocyte Growth Factor), VEGF (Vascular Endothelial Growth Factor) and more.

Collagen Main structural protein foundation to  promote skin firmness and elasticity Birch Sap(Betula alba) promotes cell proliferation, protects cells from oxidative stress, and stimulates aging cell cultures. Also, it regenerates superficial layers of skin and minimize pigmentation. It has excellent moisturizing features and positive effects on deeper layers of skin that increase elasticity of skin due to formation of new collagen.

Growth factors are secreted by all cell types that make up the epidermis and dermis of the skin including keratinocytes, fibroblasts and melanocytes. They stimulate biochemical pathways that promote skin tissue repair and regeneration.

Synergistic interaction of multiple growth factors with other proteins in epidermis and dermis results in skin repair and regeneration. Growth factors applied to the skin surface penetrate the epidermis that fertilizes your skin.

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HOW TO APPLY

Re-Acxel

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How to apply

R E-ACXE L?

The individual ampoule is vacuum sealed that can be stored in room temperature. However, opened ampoule should be stored in the refrigerator and used within 3 days.

1. Clean your face thoroughly.

2. Apply Toner to your face to gently open pores and leave skin slightly moist.

3. Apply tiny dots of Re-Acxel all over your face and neck.

4. Gently tap the surface of your face and neck with your fingers whilst Re-Acxel is still wet after applying.

5. Only when Re-Acxel is fully dry should you apply your moisturizer in a similar manner. Â

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PRODUCT D EVELOPMENT

Incorporated in 1989, STC Life has been playing the central role in the development of the stem cell and gene industries with its powerful R&D infrastructure. STC Nara Co,. Ltd, a cosmetic arm of STC Life, maintains complete quality control system according to CGMP regulations.

The skin science created from life science technologies offers an anti-aging effect that rejuvenates the aging skin cells and provide a fundamental solution beyond temporary and superficial effects.

Boasting state-of-the-art technologies, 8 STC ingredients registered in ICID (International Cosmetic Ingredient Dictionary)

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THE BEST COSMETIC PRODUCTS CREATED

BY A LIFE SCIENCE COMPANY 01. Energy Water: water changed to have a molecular structure similar to that of the water in the body 02. Persimmon Calyx Extract: a cosmetic ingredient component that includes persimmon calyx extract for wrinkle reduction and elasticity promotion 03. Umbilical-cord blood-derived stem-cell-conditioned media (STC-CSM) 04. Substance P (stem cell derivative) 05. Energy Flake Salk 06. Ecklonia Cava Extract 07. STC-MSCM: mesenchymal-stem-cell-conditioned media 08. STC-HSCM: human-stem-cell-conditioned media

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MANU FACTURING PLANT

Since Mar. 2007 ISO9001 certification Since Mar. 2007 CGMP certification Lot area: 33,058 m2 Manufactures cosmetic products, quasi-pharmaceutical products, and health foods Offers OEM & ODM services Annual output of cosmetic products: more than US$ 20 million

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A B OUT STC N A RA CGMP

ISO 9001

KFDA

ISO 9001:2008

STC has become a leader in the cosmetics industry, boasting state-of-the-art technologies, facilities, funding power, and outstanding product quality recognized internationally and certified by the Ministry of Commerce, Industry and Energy in South Korea.

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Level 25 One Raffles Quay North Tower Singapore 048583

Lauren Kim Mobile +65 8223 9030 Office + 65 6622 5856 lauren.kim@delancysgroup.com www.delancysgroup.com

Delancy’s is STC’s strategic South East Asia agency based in Singapore, and an authorized wholesale distributor of Re-Acxel.