High! Canada Magazine Issue #57 August/September 2020

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CONTENTS

EDITORIAL - 6 WOMAN IN WEED - TAMARA LILIEN - 10 SEARCHING FOR A SOLUTION - 14 DR. PRITESH KUMAR - 20 DR. ALBERTO SOLA - 23 SHAYNE NYQUVEST - 25 PAYTON NYQUVEST - 28 WHAT IS IBOGAINE - 31 WHERE IS IBOGAINE LEGAL? - 32 WATERPROOF HEMP SHOES HIT THE MARKET - 37 WOMAN IN WEED - CHRISTA LENTZ - 41 ONIT TESTIMONIAL - 48 BE BETTER WITH GREEN STRATEGIES - 52 NEWS YOU MAY HAVE MISSED - 54 KATSKANNABIS REVIEWS - 60 MISS LINOTTE’S RECIPIES - 63 MERRY MABON - 68 CLASSIFIEDS - 70


AUG/SEPT 2020 ISSUE 57 www.instagram.com/RyitPhotography www.instagram.com/reapamusic Photo of @reapamusic by @RyitPhotography

CANADA’S CANNABIS MAGAZINE


EDITORIAL - Cy Williams -

This issue we look at the Opiate Crisis in Canada and on a global scale to Dr. Alberto Sola about the unique power of Ibogaine therapy for drug addic on it becomes increasingly apparent that this - could be the thing that changes everything. Ibogaine could allow us to save so many people suffering globally. The opioid epidemic is arguably the greatest health-care crisis of the 21st century. In 2015 alone, its economic cost in the United States was es mated at more than $500 billion, largely driven by health-care costs, criminal jus ce expenses, and lost produc vity. This crisis has brought more a en on to the growing collec on of research examining the rela onship between cannabis and opiates, par cularly when it comes to reducing opioid dependence in pa ents. The magnitude and indiscriminately mortal nature of this crisis are unprecedented. For the first me in U.S. history, drug overdoses are killing more people than gun violence or motor vehicle accidents. In fact, 91 Americans die from an opioid overdose each day, according to the Centers for Disease Control and Preven on (CDC). These fatali es are tragic enough, but the residual effects on surviving children, family members, and communi es are no less devasta ng. Here in Canada we are facing an precedented na onal opioid crisis. The growing number of overdoses and deaths caused by opioids, including fentanyl, is now, more than ever, a public health crisis. Can Cannabis Help? It seems it may be able to. Weedmaps recently published a report from January 2017 in which the Na onal Academies of Sciences, Engineering, and Medicine (NASEM) reviewed more than 10,000 studies in humans to evaluate the safety and efficacy of cannabis for dozens of different diseases and symptoms. The NASEM provided an interes ng look at the rela onship between cannabis and opiates, defini vely concluding that medical cannabis, a

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Welcome back to an all new issue of High! Canada Magazine. We are pleased to bring you an all new Fall 2020 team of contributors and we look forward to bringing you the very best content we can as we come together to cover all things cannabis and beyond...


non-opioid pain-relieving drug, is indeed safe and effec ve for the treatment of chronic pain and other medical condi ons.

In fact, studies have found this is exactly what happens when chronic pain pa ents are given access to cannabis. All over the world, me and me again, experts have found that cannabis reduces opioid use by half. Pa ents also reported a huge improvement in their day-to-day lives due to cannabis’ ability to minimize the mental fog and other unpleasant side effects of opioids. It has been noted that when a U.S. state enacts a medical marijuana law, the opioid mortality rate drops by 24.8% — and that percentage goes up the longer cannabis has been legal in a state. Furthermore, non-fatal opioid hospitaliza ons also go down by 23%. And that’s true regardless of whether people are using prescrip on opioids or illicit drugs such as heroin and fentanyl. These findings aren’t en rely surprising to the addic on recovery community, in which

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In other words, cannabis and opiates work together, with cannabis enhancing the pain relief provided by opioids. That means pa ents should need lower doses of opioid-based medicines to relieve their pain.

yhpargotohPtiyR/moc.margatsni.www

What’s more, in addi onal inves ga ons of cannabis and opiates, scien sts have studied the combined administra on of opioids and cannabinoids, or ac ve molecules from the cannabis plant. This research has been ongoing for decades. Across all species, all routes of administra on, and nearly every specific opioid and cannabinoid molecule studied, these drugs produce synergis c pain relief when taken together.


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anecdotal reports about the connec ons between weed and opiates are fairly common. Specifically, these reports consistently suggest that using cannabis to wean off of opioids is both quite common and effec ve. Cannabis is said to have a number of therapeu c effects, minimizing the chills, nausea, excrucia ng pain, and mental anguish commonly associated with opioid withdrawal. This makes the first few days of opioid detox far more tolerable, boos ng the likelihood of staying sober. We also know that one of the biggest relapse triggers is nega ve mood or anxiety, and that cannabidiol (CBD) alone has powerful an anxiety effects. In preliminary studies at Mt. Sinai hospital in New York, researcher Yasmin Hurd has shown that even a single dose of CBD can inhibit the anxiety that leads to drug craving and relapse in opioid users. So many ways we can treat people suffering from addic on and we are learning about more everyday. In this issue we really look at the opioid crisis in Canada and around the world. While it appears bleak, we also able to see the shining light of possibility and hope as we take a look at some of the people out there making a real difference. Featured in this issue of High! Canada Magazine are some of the shining stars working towards ending the crisis in our life mes through advances in research and the implementa on of plant medicine into the addic on recovery equa on. People like financier Shayne Nyquvest, cannabis scien st Dr. Pritesh Kumar, thought leader in Entheogenic treatment - Dr. Alberto Sola and champion of health and human advancement - Payton Nyquvest are making the world a be er place and it is a dis nct honour to feature these superstars in this very special issue. Cy Williams Publisher/Editor - High! Canada Magazine email - editor@highcanada.net







H

SEARCHING FOR

A SOLUTION

TO THE GLOBAL

OPIOID CR IS IS WITH

igh! Canada Magazine has been travelling around the country and the world for the last number of years and in doing that we have witnessed, first hand, the damage being done to communities all over Canada by addiction. In this issue we are looking for new solutions to the current crisis that continues to plague us in so many ways. We are constantly impressed by the healing power of plant medicine. Cannabis and CBD can change your life. So can Delta 8’s and 9’s and what about the healing power of microdosing. There are so many other types of plant medicines that work well in conjunction with each other. Now is the time to see what they can really do.

MANAGING DIRECTOR OF PHYTOSCIENCES

- CANNABIS SCIENTIST & RESEARCHER-

DR. PRITESH KUMAR C E O & F O U N D E R A T NUMINUS | HEALTH & HUMAN ADVANCEMENT

PAYTON NYQUVEST FUNDING THE FUTURE WITH

SHAYNE NYQUVEST IBOGAINE INTERNATIONAL & CLEARSKY RECOVERY PRESIDENT

- THOUGHT LEADER IN ENTHEOGENIC TREATMENT -

DR. ALBERTO SOLA

This feature takes the opportunity to feature four men who are actively working on solutions to the current opioid crisis. In this feature, we look at cannabis scientist, Dr. Pritesh Kumar who believes his research may hold the answer to helping end the crisis. We also feature Dr. Alberto Sola and Shayne Nyquvest - who are poised to change the world and create a new standard for addiction treatment with Ibogaine. Lastly we check in with Payton Nyquvest who is making history and changing the world with Numinus.


OPIOID MORTALITY SURVEILLANCE REPORT

ANALYSIS OF OPIOID-RELATED DEATHS IN ONTARIO BETWEEN JULY 2017 AND JUNE 2018 Over the past decade, there has been an increase in the number of both fatal and non-fatal opioid-related toxicity events across Ontario. Pharmaceutical and non-pharmaceutical opioids, as well as other non-opioid substances have contributed to these deaths. Between July 2017 and June 2018, there were 1,337 confirmed opioid-related deaths in Ontario, Canada, the majority of which were accidental (N=1,209, 90.4%).

AMONG ACCIDENTAL DEATHS

SUBSTANCES INVOLVED Fentanyl and fentanyl analogues contributed to nearly

¾ of deaths.

Other non-opioid substances directly contributed to death: 34% cocaine

15% methamphetamine

DEMOGRAPHICS

¾

were male

13% alcohol

11% benzodiazepines

½

Over were individuals between the ages of 25 and 44


DEMOGRAPHICS

¾

were male

½

Over were individuals between the ages of 25 and 44 Employment status:

Lived in: 74% a private residence 62% large urban centres 32% areas with high material deprivation

47%

18%

unemployed

employed

33% unknown

employed worked in 31% ofthethose construction industry

CIRCUMSTANCES SURROUNDING DEATH

½

Nearly were alone at time of incident

½

Almost involved a resuscitation attempt

3/

5

of incidents occurred in the person's own home

1 Over / 5

had naloxone administered

FOR MORE INFORMATION Read the Opioid Mortality Surveillance Report www. odprn.ca/opioidmortality/ www.publichealthontario.ca/opioidmortality


Looking at the Opioid Crisis in our own communi es and worldwide - it is tragic to see the damage done and s ll being done by opiate addic on. Canada is facing a na onal opioid crisis. The growing number of overdoses and deaths caused by opioids, including fentanyl, is a now public health crisis in our Country.

Coroners Office released a report en tled Preven ng Pharmaceu cal OpioidAssociated Mortality in Bri sh Columbia: A Review of Prescribed Opioid Overdose Deaths, 20092013. The report addresses morbidity and mortality associated with pharmaceu cal opioids which is a cri cal public health issue in Bri sh Columbia.

review of pharmaceu cal opioid-associated overdose fatali es of BC residents between 2009 and 2013 and linkage between BC Coroners Service file informa on and administra ve health dataset, including prescrip on drug d i s p e n s a o n h i s t o r y, medical services u liza on, and hospitaliza ons.

The Office of the Chief Coroner for Ontario and Public Health Ontario have co-published a report that describes the current trends and characteris cs of confirmed opioidrelated deaths in Ontario between July 1, 2017 and June 30, 2018. The report aims to advance understanding of the current rise of opioidrelated deaths in that province, as well as inform public health prac ce and syste m p l a n n i n g t h at addresses opioid-related harms in the province.

This report presents key findings of an ini al inves ga on of uninten onal overdose deaths involving prescribed pharmaceu cal opioids.

In the US in 2015 more than 1 in 3 Americans were prescribed an opiate for pain relief and according to t h e C D C a d a n ge ro u s misuse of those medica ons brought one thousand users to the ER every day.

In the Summer of 2017, in Bri sh Columbia the BC

The research design involved a retrospec ve


BC Coroners Service

Illicit Drug Toxicity Deaths in BC January 1, 2010 to July 31, 2020

Table 1: Illicit Drug Toxicity Deaths by Month, British Columbia, 2010-2020[3] Month

2010

2011

2012

2013

2014

2015

2016

2017

2018

2019

2020

Jan Feb Mar Apr May Jun Jul Subtotal Aug Sep Oct Nov Dec Total Average

16 14 15 9 22 21 23 120 24 20 18 18 11 211 17.6

24 24 25 27 22 22 33 177 22 22 23 27 24 295 24.6

20 17 25 31 19 25 29 166 20 16 19 28 21 270 22.5

20 21 33 31 28 25 39 197 21 28 19 31 38 334 27.8

23 38 28 29 40 29 25 212 37 32 35 28 25 369 30.8

43 31 32 34 41 34 40 255 53 50 53 52 66 529 44.1

85 58 76 72 51 71 74 487 64 63 76 140 161 991 82.6

147 125 130 154 149 128 123 956 127 97 99 112 104 1,495 124.6

134 108 157 136 119 116 147 917 123 135 118 132 122 1,547 128.9

94 85 116 85 88 76 74 618 86 59 75 79 67 984 82.0

78 73 113 119 174 177 175 909 909 129.9

Comparison to Other Common Causes of Unnatural Deaths from 2010 to 2019:

Figure 2: Major Causes of Unnatural Deaths in BC 1800 1600 1400

Deaths

1200 1000 800 600 400 200 0 2010

2011

Illicit Drug

2012 Suicide

2013

2014

2015

Motor vehicle incident

2016 Homicide

2017

2018

2019

Prescrip on Drug

*Prescription drug toxicity deaths (accidental and undetermined) include cases where only a prescription drug is involved and reported for closed investigations only to 2018.

Posting Date August 25, 2020


dispensa on history, medical services u liza on, and hospitaliza ons. In the US in 2015, more than 1 in 3 Americans were prescribed an opiate for pain relief. According to the CDC, a dangerous misuse of those medica ons brought one thousand users to the ER every day. According to a report by the American Society of Addic on Medicine - Drug overdose is the leading cause of accidental death in the US, with 52,404 lethal drug overdoses in 2015. Opioid addic on is driving this epidemic, with 20,101 overdose deaths related to prescrip on pain relievers, and 12,990 overdose deaths related to heroin in 2015. From 1999 to 2008, overdose death rates, sales and substance use, disorder treatment and admissions related to prescrip on pain relievers increased in parallel. Looking back, the overdose death rate in the United States of America in 2008 was nearly four mes the 1999 rate.


D

r. Pritesh Kumar is the Managing Director of PhytoSciences GmbH, a Switzerland based consultancy made up of scien sts & analysts from across the EU, Africa, Canada, India, and USA. Dr. Kumar has a diverse set of skills and experiences in the fi e l d s o f st r u c t u r i n g & commercializing science assets, risk advisory, and investment due diligence. Dr. Kumar holds a Ph.D. in Pharmacology and Toxicology, with a focus in cannabinoid (cannabis) pharmacology, from the University of Louisville, School of Medicine. Canada is suffering from one of the worst opioid epidemics in the world. Despite being highly addic ve, drugs such as fentanyl, morphine, and oxycodone are commonly prescribed to anyone recovering from surgery, suffering from an injury, or managing pain from a chronic condi on. When prescrip ons run out, or pa ents develop a

SEARCHING FOR

A SOLUTION

TO THE GLOBAL

OPIOID CRISIS WITH MANAGING DIRECTOR OF PHYTOSCIENCES - CANNABIS SCIENTIST & RESEARCHER-

DR. PRITESH KUMAR


tolerance, they’re usually s ll in pain, but now craving a new source of relief. This o en leads them to seek even more dangerous op ons from illegal sources.

With hundreds of thousands of Canadians addicted or dependent on opiods, Dr. Pritesh Kumar, a cannabis scien st, believes his research may hold the answer to helping end the crisis. Dr. Kumar first began researching opioids in Canada in 2016. He conducted a study that compared how well pharmaceu cal-grade cannabis treated chronic pain compared to the overprescribed narco c alterna ves. Consistent with anecdotal evidence and research in other countries, pa ents found that cannabis was just as painrelieving, with less nega ve side effects. Considering opioids were never intended for long-term use, this was not surprising. Dr. Kumar wants to expand on this research. His new mission is to inves gate how medicinal cannabis can be used to help lessen symptoms of withdrawal that occur when opiod use stops. This could not only help people succeed in their recovery and prevent relapses, but in situa ons where doctors

do prescribe opiods, it could help pa ents safely transi on off the drug. Dr. Pritesh Kumar has dedicated his life to establishing a credible, science-based approach to researching the medical effects of cannabis. As the managing director of Phytosciences, an interna onal cannabis consul ng firm, Dr. Kumar is considered the leading expert on medicinal marijuana and cannabinoid tes ng. He believes cannabis is a powerful medicine that should be available in a safe form to those who need it. Dr. Kumar has provided consul ng services to several U.S. state government officials as well as interna onal governments and policy officials on effec ve medical cannabis policies. He regularly advises on laboratory facility design / op miza on, cannabis tes ng equipment, analy cal methodology for cannabinoid analysis and separa on, pharmacology of cannabis-based therapeu cs and maintaining a QA system to ensure compliance, including prepara on of legisla ve documents to regulate a QA syste m w i t h re ga rd to ca n n a b i s manufacturing and processing.



D

r. Alberto Sola has the dis nc on of having treated more pa ents with Ibogaine than any other person in the world and is Head of Opera ons at Clear Sky Recovery.

“I established Clear Sky Recovery Cancun 17 years ago. Since then I have administered more than 3,500 ibogaine treatments for addic on, and we developed a protocol to provide ibogaine safely and effec vely. Universal Ibogaine brings this unique, powerful treatment first to Canada, and then to the world to fight the opioid crisis and the global addic on pandemic. Our goal is to create the gold standard for addic on treatment with ibogaine-assisted psychotherapy. To do this, we must first put ibogaine through clinical trials with Health Canada, and then we will build a network of holis c recovery clinics known as Clear Sky Recovery to treat the roots of addic on using ibogaine.

SEARCHING FOR

A SOLUTION

TO THE GLOBAL

OPIOID CRISIS WITH IBOGAINE INTERNATIONAL & CLEARSKY RECOVERY PRESIDENT

- THOUGHT LEADER IN ENTHEOGENIC TREATMENT -

DR. ALBERTO SOLA


Current treatment op ons for opioid and other forms of addic on only work for some people. What’s missing is the ability to fast track the withdrawal process. Ibogaine — a molecule found in Tabernanthe iboga and many other plants — is showing the poten al to aid in rapid detox. In combina on with an effec ve therapeu c se ng, it aims to help addicts in the recovery process. Universal Ibogaine Inc.’s goal is to provide safe, effec ve and affordable ibogaine treatment globally this decade.” Born in Barcelona Spain, Dr. A lb er to So là is a b o a rd cer fied emergency medicine physician. He trained in Mexico City and graduated from Universidad Anahuac. As of 2013 he s ll prac ced emergency medicine in a 250 bed teaching hospital in Cancun. He prac ced tourist medicine with Amerimed Hospitals corpora on from 1996 un l 2006 in Puerto Vallarta, Cancun and Cabo San Lucas. Dr. Solà was head of medical opera ons, in

charge of hiring, managing and supervising 98 doctors and 72 nurses including orthopedic surgeons, anesthesiologists, radiologists, ER physicians, and full hospital staff. Dr. Solà spearheaded the establishment of 4 new hospitals including architectural planning, hiring of medical personnel, and all daily opera ons. Secured and managed contracts for on-site medical care & pa ent transport with 11 major hotels & cruise lines in Cancun (e.g., Carnival Cruise lines, Marrio , Intercon nental, The Palace hotels) and acted as a supervisor overseeing medical care services for all major spring-break, student-oriented tourism companies in Cancun. In 2004 Dr. Solà began training with Dr. Deborah Mash in St. Ki s. Under her direct supervision, he established a detox centre in Cancun where he has personally administered thousands of ibogaine treatments to date. As of 2018 Dr. Sola is one of the world’s leading experts in medically-based ibogaine treatment; he has more clinical experience with safe and effec ve ibogaine administra on than any other M.D. in the world today. He is fully bilingual in English and Spanish.

Dr. Solà Honors and Awards: Cer ficate of Apprecia on from the White House Medical Unit 2006. Assistance and Facilita on of President George W. Bush’s official visit to Cancun, Mexico. Professional Socie es: Member of American Society of Addic on Medicine (ASAM) Member of Mexican Society of Emergency Medicine Member of Medical College of Quintana Roo, Mexico Research Training: Ibogaine treatment for substance abuse Deborah C. Mash, Ph.D., St. Ki s


L

ong me Canadian Financier Shayne Nyquvest has a solu on to the Global opiate crisis and that solu on is Ibogaine. Shayne has made it his personal mission to make sure it’s done right. “With addic on recovery, Ibogaine is, in my opinion, something that can move the needle in an industry with a 95% failure rate.” Shayne credits growing up on the wrong side of the tracks in W i n n i p e g fo r h i s u n i q u e perspec ve on financing. “My training was basically in how to make big ones out of li le ones and that's the only thing that ever really interested me. I'm not much for anything else. It's a very simple formula get good people to finance good companies.” “We financed a few Diamond companies following this formula. We were involved in 12 of the first 15 marijuana deals that launched in Canada. Now those same people are looking at the Psychedelic sector that is about to emerge

SEARCHING FOR

A SOLUTION

TO THE GLOBAL

OPIOID CRISIS FUNDING THE FUTURE WITH

SHAYNE NYQUVEST


and what the benefits of that would be. Coming to the table is the granddaddy of all the Psychedelics and it is coming to the Forefront fast. I started asking myself how can I help? I want people to turn their lives around, to get their lives back, to get their families back. We're here to try and make a difference. How did I b e c o m e c o nv i n c e d ? I probably have referred 30 to 50 people down there and in 2 years and there were no problems, only successes. I also had a problem and I dealt with it by ge ng into the clinic and going through the whole process myself. In my mind, this is a gamechanger and it baffles me how it has not progressed as rapidly as I would like to have seen it happen. There has to be a regulatory process of approvals and clinical trials and we spent the last year-and-a-half and couple million dollars ge ng a safety protocol going to move forward to

the clinical trials. Kudos to Health Canada for being one of the na ons in the world that was smart enough to keep it on their Special Access Program. We have a clinic in Cancun that has processed 3,700 people with a zero death rate, ge ng people through detox rela vely painlessly over the first 18 hours. Yes, I know how hard that is to believe, but believe it from me that the safety protocol is foolproof. We've had no casual es or no events of any concern. For about 15% of people they are screened out, because they have heart problems, mental detachment problems or they are chronic diabe cs. We are as safe and s e l e c ve a s p o s s i b l e . Ibogaine is not a silver bullet. What keeps people in addic on for decades at a me is the pain of going through withdrawals and with Ibogaine there is no Post Acute Withdrawal Syndrome. What we are g o i n g to d o i s a p re -

screening and if you're a successful candidate for Ibogaine you are in. A er that, the actual treatment experience is roughly an eighteen hour experience. If you want it in layman's terms - you have a neural sensor in your brain and it is like a wire with insula on covering it and years of addic on have worn the insula on off. Ibogaine rebuilds that insula on. It has been doing this for a thousand years in men's and boys treatments in Africa. It literally takes you back to a pre-addicted state so that 36 hours later, you won't need to feed that monster and the withdrawal is gone. You can actually concentrate on recovering and revealing the trauma or whatever it is that got you to the point that you're at. It is a new global standard for Addic on Treatment. This will change the world. I know this to be true.


Addressing the Universal Desire to Heal. 4,000

The number of Canadians who die by suicide per year – almost 11 suicides per day

50%

Percentage of Canadians experiencing a major depressive episode that do not receive “poten ally adequate care”

9%+

Percentage of Canadian adults who will suffer PTSD In their life me

$51B

Es mated annual economic burden of mental illness in Canada

Transforma ve change is needed

#4

Canada’s rank in the use of a n depressant drugs per capita. The use of an depressants is on the rise globally.

500,000

Number of unemployed Canadians who are unable to work due to mental health problems

1 in 2

The number of Canadians who will be affected by mental health issues by the age of 40

1 in 5

The number of Canadians who suffer from addic on in any given year


P

ayton Nyquvest stands behind the belief that the societal costs of mental illness, addic ons, trauma, and unmet human poten al are much too high. He is the CEO and Founder of Numinus Health & Human Advancement who have been licensed by Health Canada to produce and extract psilocybin from mushrooms. Numinus is at the forefront of a d d re s s i n g t h e g ro w i n g prevalence of mental health issues and desire for overall greater wellness. One in ďŹ ve Canadians suer from addic on in any given year, and deaths from the c u r re n t o v e rd o s e c r i s i s a ributable to opioid and other addic ons are growing. Companies of note Numinus a n d To g e t h e r W e C a n A d d i c o n Re cove r y a n d Educa on Society (TWC) share the view that new solu ons and integra ve approaches are needed to enhance tradi onal recoverybased approaches to help people make transforma ve change, heal, and be well. The partnership announced this summer currently

SEARCHING FOR

A SOLUTION

TO THE GLOBAL

OPIOID CRISIS

WITH CEO & FOUNDER AT NUMINUS | HEALTH & HUMAN ADVANCEMENT

PAYTON NYQUVEST


extends the con nuum of care provided t o T WC c l i e n t s w i t h s p e c i a l i ze d mind/body programs which include m o d a l i e s s u c h a s n at u ro p at hy, registered massage therapy, trauma and soma c therapies, and breathwork through Numinus's associated wellness clinic in Vancouver. Individualized programs are con nually being d e ve l o p e d fo r To get h e r We C a n Addic on Recovery and Educa on Society clients, including Canadian Forces members and veterans dealing with addic on, PTSD, anxiety, grief and loss, and other diagnoses. Numinus has received Health Canada approval to amend the Company’s exis ng licence under the Controlled Drug and Substances Act to allow Numinus researchers to conduct research to standardize the extrac on of psilocybin from mushrooms. The amendment means Numinus is the first publicly traded company in Canada to be granted a licence by Health Canada to conduct research of this kind. With this regulatory approval, Numinus is able to proceed with the produc on of naturally sourced, sustainable psilocybin for research purposes that will support the emerging field of psychedelicassisted psychotherapy and research, at

lower costs to currently produced synthe c psilocybin. The licence also allows Numinus to develop and licence its own exclusive IP for further product development in partnership with leading research organiza ons — something the research community has been seeking to secure. The company’s exis ng licence (in alignment with licence holder Salva on Botanicals Ltd) allows Numinus to test, possess, buy and sell MDMA, psilocybin, psilocin, DMT, and mescaline. Numinus is dedicated to providing access to therapies that enhance and supplement exis ng op ons. Psychedelics will be part of this but will only be available for treatment once approved by regulators and governing bodies.

Payton and Numinus are

addressing the universal desire to heal

and in doing so are opening up countless new roads for healing.



E N I A G IBO R E M I R P

WHAT IS IBOGA/IBOGAINE?

I

bogaine is a crystalline alkaloid hallucinogen C20H26N2O obtained from the roots, bark, and leaves of the Tabernanthe iboga plant of the

dogbane family (Apocynaceae) that is found in equatorial Africa. Tabernanthe iboga is a perennial rainforest shrub na ve to West Africa.

An evergreen bush indigenous to Gabon, the Democra c Republic of Congo, and the Republic of Congo, it is cul vated a c ro s s We st A f r i ca .


WHERE IS IBOGAINE LEGAL? If you are searching for an Ibogaine therapy centre, be selec ve. A high-quality ibogaine treatment centre priori zes safety, prac ces under medical supervision, and follows clinical guidelines.

Australia. In 2010, Ibogaine was scheduled as a Schedule 4 substance on Australia’s Poisons List. It remains a Schedule 4 substance pursuant to the February 2019 Poisons Standard, which means it is a Prescrip on Only Medicine. Brazil. Ibogaine is legal to possess and distribute in Brazil. In Sao Paolo, Brazil’s capital city, Ibogaine must be administered


Ÿ In a medical environment where adequate pa ent protec ons are in place. On January 24, 2016, the President of the Na onal Associa on of the Study of Drug Policy (CONED-SP) in Sao Paolo issued a declara on calling for the scien fic study o f p syc h o a c ve s u b sta n c e s , a n d approving the medical use of ibogaine “in a hospital environment, with medical supervision and control, mee ng the exercise of the profession and the recommenda ons of good clinical prac ce, including rigorous clinical and psychiatric examina ons and psychological assessment and p s y c h o t h e r a p e u c m o n i t o r i n g .” Ÿ Costa Rica. In Costa Rica, Ibogaine was legal for some me, but it is no longer l e g a l a s o f 2 0 1 8 . Ÿ Gabon. Gabon lies on the west coast of central Africa. The na onal law of Gabon protects iboga plants. Ÿ Guatemala. It is legal to treat with Ibogaine in Guatemala. An Ibogaine treatment centre is located in An gua, which is located near Guatemala City. Ÿ Mexico. Ibogaine is legal but unregulated in Mexico. Therefore, Mexico is a popular spot for ibogaine treatment. Ÿ Netherlands. The Netherlands does not prohibit Ibogaine, and there are various ibogaine treatment centres available.

Ÿ New Zealand. Ibogaine has been medicalized in New Zealand and can be obtained with a prescrip on and taken under medical supervision. As a result, you can go to an Ibogaine treatment centre in New Zealand that offers an Ibogaine prescrip on under the supervision of a medical p r o f e s s i o n a l . Ÿ South Africa. The South African government has licensure procedure in place for those who want to provide medical Ibogaine treatment.

Ibogaine is illegal in the following countries: Belgium Costa Rica Denmark France Hungary Ireland Italy Norway Switzerland Sweden The UK The United States Ibogaine is not a scheduled substance and it’s status for medical use to interrupt drug dependence disorders remains in ques on in Canada, and Israel.


Since Ibogaine was introduced to the western world as an addic on interrupter it has been slow to gain approval as a prescrip on medicine for various reasons, despite the success of the early phases of clinical trials and con nued research. Ibogaine is a naturally occurring psychoac ve substance that has been demonstrated to interrupt substance use disorders, as well as possess other neurological and psychological benefits. It is found naturally and has been used for centuries by tradi onal communi es in West Africa for ritual and healing purposes. In lower doses, Ibogaine acts as a s mulant, increasing energy and decreasing fa gue in a way that is dis nct from other central nervous system s mulants like amphetamines and cocaine. In larger doses, Ibogaine produces oneirogenic effects, meaning that it s mulates

a dream-like state while awake, as well as closed e ye i m a g e r y a n d t h e retrieval of repressed memories. Its physical effects can include ataxia, nausea and vomi ng, sensi vity to light and sound, tremors, and cardiac effects. In the early 1960’s, the Chilean psychologist Claudio Naranjo conducted 40 Ibogaine sessions with his clients and was the first to scien fically describe the experience. He reported t h at I b o ga i n e h e l p e d people to view difficult experiences in an objec ve way, and that it helped to facilitate closure of unresolved emo onal conflicts. The occidental use of Ibogaine, especially its applica on in the treatment of substance use disorders, was pioneered by Howard Lots. In 1962, 19 year old Lots found that a single dose of Ibogaine not only interrupted his physiological dependence

on heroin, it also took away his craving to use, all with no withdrawal symptoms. Lots of spent the rest of his life advoca ng for the development of Ibogaine as a prescrip on medicine. In the early 1990’s, the US Na onal Ins tute on Drug Abuse (NIDA) began the development of Ibogaine by fully funding pre-clinical animal trials as well as Phase 1 safety trials on human subjects under the auspices of Dr. Deborah Mash at the University of Miami. The results confirmed that Ibogaine decreases the selfadministra on of s mulants, opiates and a l co h o l , a s we l l a s a significant reduc on in the withdrawal symptoms from opiates. ((Popik P, Glick S. Ibogaine, a puta vely an -addic ve alkaloid. Drugs of the Future. 1996; 21:pp 11091115.)) U n f o r t u n a t e l y, t h e development research was ended prematurely


rela ve to NIDA’s exis ng resources. Phase 1 safety trials conducted by NIDA found that Ibogaine is not n e u ro tox i c . H oweve r, there are a number of fatali es that have been temporally associated with the inges on of Ibogaine. These were a ributed to a variety of factors, including preexis ng medical condi ons, especially cardiac condi ons, as well as seizures resul ng from acute withdrawal from a l c o h o l o r benzodiazepines, and in other cases the coadministra on of one or more drugs of abuse. One of the causes cited is that Ibogaine poten ates the effects of opiates, as well as their lethality if coadministered. It does this not by ac ng as an opiate agonist or antagonist, but by enhancing opiate signalling. Another is that, in addi on to a enua ng withdrawal symptoms, ibogaine has been shown to reduce developed tolerance to opiates and

alcohol, essen ally returning the user to a novice state. Using substances a er administra on of ibogaine without taking this into considera on presents a significant risk of overdose. In the late 1980’s, the first regular Ibogaine-assisted detox sessions were conducted by the Danish Drug Users Union in Amsterdam. Over the last several decades a global community of ibogaine therapy providers, which has been dubbed a “medical subculture,” has developed to include former drug users and physicians. In 2007 it was es mated that over 3,400 therapy sessions for substance use disorders, as well as for personal and spiritual growth, had been conducted worldwide. This number con nues to grow annually, as well as the number of clinics. Ibogaine-assisted detox efficacy has been explored in two recent studies being

conducted by the Mul disciplinary Associa on for Psychedelic Studies (MAPS), a emp ng to track the long-term efficacy of ibogaineassisted detox therapy. The studies, in Mexico and New Zealand, have re p o r te d p re l i m i n a r y results of between 20% and 50% rate of clients remaining free from their primar y substance of abuse for at least 12 months. Factors influencing this range were suggested to be the ease of follow-up in the New Zealand study become of closer proximity, as well as other factors such as plans for con nuing care.

Ibogaine therapy m a y h a v e promising results in the treatment of other condi ons, including Hepa s C , P a r k i n s o n ’s disease and To u r e e ’ s syndrome.


Credits: D.C. Mash, C.A. Kovera, B.E. Buck, Juan Sanchez-Ramos. Medica on development of ibogaine as a pharmacotherapy for drug dependence. Annals of the New York Academy of Sciences 844:274-92 · June 1998

“Modifica on of awake-sleep equilibrium by tabernanthine and some of its deriva ves in the cat.” Da Costa L, Sulklaper I, Naquet R. Review of Electroencephalography and Clinical Neurophysiology. 10:105-112. 1980.

Kaplan, C.D., Ketzer, E., de Jong, J. and de Vries, M. Reaching a state of wellness: Mul stage explora ons in social neuroscience. Social Neuroscience Bulle n, 1993, 6: 6-7.

Mash DC, Kovera CA, Pablo J, Tyndale RF, Ervin FD, Williams IC, Singleton EG, Mayor M. Ibogaine: complex pharmacokine cs, concerns for safety, and preliminary efficacy measures. Ann N Y Acad Sci. 2000 Sep;914:394-401.

The Healing Journey. “Ibogaine: Fantasy and Reality.” Claudio Naranjo. New York, 1974. Read full chapter.

Deborah C. Mash, Craig A. Kovera, and John Pablo, Rachel Tyndale, Frank R. Ervin, Jeffrey D. Kamlet, W. Lee Hearn. Ibogaine in the Treatment of Heroin Withdrawal THE ALKALOIDS, Vol.56, 2001 Academic Press. ↩

Alper, Kenneth R. M.D., Marina Stajic, Ph.D., and James R. Gill, M.D. Fatali es Temporally Associated with the Inges on of Ibogaine. Journal of Forensic Sciences, March 2012, Vol. 57, No. 2.

Trujillo KA & Akil H, Inhibi on of Morphine Tolerance and Dependence by NMDA Receptor Antagonist MK-801, Science, 2512:85-87, 1991.

Khanna JM, Kalant H, Shah G, Chau A, Effect of D-cycloserine on Rapid Tolerance to Ethanol, Pharmacology Biochemistry & Behavior 45(4):983-986, 1993.

Kenneth R. Alper, Howard S. Lotsof, Charles D. Kaplan. The ibogaine medical subculture. Journal of Ethnopharmacology. 115: 9–24. 2007.

h ps://www.ibogainealliance.org/ibogaine/


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TESTIMONIAL UNLOCKING THE FULL GENETIC POTENTIAL OF EVERY PLANT An Oregon Grower tells us about his Experience with Onit Sciences. His experience using Onit on Cannabis plants has been very posi ve. “ ‘My regimen is a foliar spray on the plants star ng at the cloning stage (when they are in the cloner) through the vegeta ve phase.’

My applica on rate is 13 ml / gallon. My applica on period is every 5-7 days. I con nue the applica on interval and rate when they enter the flowering phase for about 5 weeks, or un l I am a month out from harves ng. I always apply Onit at least an hour before the lights go on, giving the leaves mes to dry off. The Results! I am witnessing for Cannabis show a 12% increase in yield, or about 0.13 lbs per plant. This has been over 4 harvests in a indoor se ng using a coco fiber growth medium. Onit provides several benefits in the Cannabis plant cycle;


Organic non GMO all natural non-toxic 1. Overall the plants are healthier, and exhibit a deeper and richer green color in the leaves. You can actually see the plant change its energy level within a few hours of using a foliar spray, by stretching out and reaching for the light. 2. Because of the pH of my typical Onit foliar spray is around the 4.0 range, the surface of the leaves become acidic and this seems to reduce powdery mildew problems 3. Onit mixes in very well with other foliar treatments.. I always include it with foliar applica ons of nutrients or enzymes. 4. When transi oning to the flowering phases, the plants take on a crazy rate of growth, much more so then my pre-Onit days. I have a lot more flower sites on each stem, resul ng in a higher yield average of +12%. 5. Onit is very cost effec ve for me as a foliar spray. Each plant uses about $2.00 of Onit through its en re life cycle, and the value of the increase in yield per plant is $195. Wow! ONIT Grow™ is a registered organic input that enhances plant and soil health -naturally. Realworld results ONIT Grow™ has been proven effective at

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NEWS YOU MAY HAVE MISSED AUTUMN 2020 flower and nearly 150,000 pounds of total cannabis products.

THE LARGEST LEGAL CANNABIS HARVEST IN HISTORY IS HAPPENING IN SEPTEMBER 2020 NEAR KELOWNA, BC, AT SPEAKEASY GROWERS. Located in the small town of Rock Creek, about a two -h o u r d rive fro m Kelowna, a staggering 60,000 plants have reached full blossom on the 60-acre SpeakEasy cannabis farm. The harvest is expected to produce about 70,000 pounds of premium

“Based on all the informa on we’ve received, this is the single largest harvest to date, but that record probably won't last for long ,” laughed Marc Geen, CEO of SpeakEasy. “These plants cover over 2.6million square feet and Aurora Sky is the largest single indoor facility in the world at 1.4-million square feet.” While it’s a daun ng task, the Geen family is familiar with farming thousands of acres and has done

with tree fruits in the Okanagan for over four genera ons. “It’s a similar co n c e p t to c h e r r i e s , having mul ple varie es of cannabis finishing their grow cycle at different mes instead of trying to tackle a 60-acre harvest in a week,” explained Geen, who’s family also owns Jealous Fruits. “Employment wise, it falls into a nice sweet spot where cherry picking has finished and apple season has yet to start so there’s a surplus of farm labour available.” SpeakEasy has 82 people on staff, but the farm will hire more than a dozen helping hands for the


harvest over the next three weeks. Time is of the essence due to the short outdoor shelf life of the plants that can quickly grow past maturity or be hit with rain and even early season frost. However, from the me the cannabis goes in the ground in July, there couldn’t be a be er climate than Rock Creek a n d t h e s u r ro u n d i n g region. “There’s a very hot and dry heat with almost no rainfall, which is perfect for outdoor growing,” said Geen, who first moved his family to the 2,200-acre ranch in 1995 to grow ginseng and then cherries.

“We're prone to some cooler nights than the Okanagan, but that actually promotes resin produc on in the plant at this point in the grow." The harvest is expected to be even larger in 2021 when SpeakEasy’s 50,000

square foot indoor growing facility will be ready to produce its first crop. W i t h T h a n ks to Dylan McCullough. www.kelownanow.com/ watercooler/news/news/ Cannabis/The_largest_le gal_cannabis_harvest_in _history_is_happening_n ear_Kelowna/


DUTCH LOVE CANNABIS OPENS THIRD TORONTO LOCATION IN QUICK SUCCESSION Industry leader rolls ahead with expansion in Toronto’s Leslieville d e s p i t e g ro w i n g p a n d e m i c a n d regulatory slowdowns felt by cannabis retail operators TORONTO, Sept. 15, 2020 (GLOBE NEWSWIRE) -- Dutch Love Cannabis, (“Dutch Love”) today announces the launch of its fi eenth retail loca on, na onally. Located in Toronto’s Leslieville neighbourhood (20 Leslie Street), the 2,500 square-foot store is the company’s third Toronto loca on, joining Dutch Love Parkdale which

opened last month and the group’s Yonge-Dundas loca on. The con nued expansion demonstrates Dutch Love’s ability to pursue consistent and significant growth in an industry that has been overwhelmed by delays and restric ve regula ons this year. “Our ini al goal was to bring the Dutch Love Cannabis experience to 15 neighbourhoods in Ontario this year. With today’s opening in Leslieville, we’ve hit eight. As we hone in on our goal, we’re incredibly grateful to our talented team and the dedica on they’ve shown in helping us expand our footprint and connect with new communi es across the country,” says Harrison Stoker, Vice President at


Donnelly Group. “Since

legaliza on, Ontario’s retail cannabis space has faced quite a few hurdles, all on top of the COVID-19 pandemic. Despite the many snags which have presented t h e m s e l v e s , I ’m op mis c for the con nued growth of the industry and excited for our peers, fellow retailers, and the neighbourhoods we come to call home.”

In addi on to joining the local Leslieville BIA, Dutch Love will extend its ‘Good Neighbour’ program to the nearby New Hope Leslieville Salva on Army. As an extension of the company’s charitable arm, the Donnelly Fund, which works within communi es facing challenging social issues, the Good Neighbour program will donate 10 percent of proceeds earned from the store’s first opera ng month. About Dutch Love Cannabis Dutch Love Cannabis, formerly Hobo Cannabis Company, is a Donnelly Group venture and Canadian collec on of 15 privately-owned retail cannabis stores with loca ons in B.C., Ontario, and Alberta. Named in testament to Amsterdam in the Netherlands, a well known (decriminalized) des na on for cannabis tourism and leader in des gma zed cannabis use, Dutch Love Cannabis is commi ed to delivering a best-in-class cannabis buying experience that is disarming, compassionate and human while employing a contemporary aesthe c rooted in simple, func onal design that features a wellconsidered product range and fric onless technology. Dutch Love Cannabis offers consumers a selec on of five cannabis intents: Move (THC dominant), Li (THC leaning), Balance (equal parts THC to CBD), Calm (CBD dominant), and Rest (THC dominant). For more informa on, visit www.dutch.love



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7daw ( Seven Days A Weed) has become the new pla orm consumers are visi ng to seek all of their cannabis needs.With all of the traffic they’re ge ng and the influx of customers, they will be launching their new app in just a few weeks. S7DAW has grown a reputable Instagram (@S7DAW) following where they consistently broadcast all of their latest and greatest announcements. S7DAW has been in the works since late 2019 but finally launched, immediately post pandemic lockdown on March 17, 2020. Timing now seems just right as new vendors are looking for a new pla orm to adver se their products, services and brand, where they can connect with the everyday consumers. The flood of vendors looking for a new pla orm has increased because of Weedmaps, a popular app for cannabis vendors to adver se just as well , has announced that they have decided to divert their a en on to focus on suppor ng licensed companies. This has le cannabis

vendors scrambling, trying to find a new pla orm to adver se. Something that we have all come accustomed to is how convenient it is to use an app to get the best meds delivered to you.

As great as what Weedmaps has done for the industry, the cost of adver sing there has been astronomically costly and almost unaffordable. The goal of S7DAW is to bring the adver sing cost back to a more reasonable level in hopes that it will be paid


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@S7DAW forward to the consumers. Many consumers are lost a er finding out that their go-to s o u rc e w i l l n o l o n ge r b e available. That is why, this is now the me to start informing the community that S7DAW will be around and available 24/7! They already have so many well know and loved companies on their website today! S7Daw aims to, eventually, take over as the source for all things cannabis- such as your local dispensaries, accessories and much more.

carry on the modern way of where to fulfill your cannabis. This will not be the last me you'll be hearing about S7DAW. With a surge of requests across Canada for services the S 7 D AW s i t e i s r e a c h i n g unimaginable levels of interest. When they asked some businesses how they heard about S7DAW, they were in fact informed that their Weedmaps’ reps told them to reach out to S7DAW. I guess you can truly say they’ve been handed the torch to

For further inquires on how to sign up on this new and exci ng pla orm as a business or client, simply send an email to info@s7daw.com, visit their website at www.s7daw.com or send a DM to their Instagram

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To finish the feast we have a fresh strawberry sherbet that will sa sfy and s mulate your tastebuds. This will fill your body, soul and spirit. With Miss Lino e it is always fun and delicious!!!


SPICY WINGS LINOTTE INGREDIENTS - 24 chicken wings - 2 tb smoked paprika - 1 tb tomato paste - 1 ts sambal olek - 2 tb maple syrup - 2 pieces of garlic minced - few drops of Worcestershire sauce - THC infused avocado oil - CBD Isolate - salt and pepper BLUE CHEESE DIP - 1/2 cup of Gorgonzola or other blue cheese - 3/4 cup of milk - 1/4 Greek yogurt - 1/4 cup hemp seed - 100 mg CBD isolate

WINGS 1. Rinse and dry wings. Mix all the ingredients together except wings. If the paste is too thick add oil. 2. Put everything together into a ziplock bag the paste and the wings, let it rest a couple hours in the fridge. 3. Preheat oven a 425 F 4. Display the wings on a baking sheet cover with parchment paper and bake 20 minutes BLUE CHEESE DIP 5. Put Gorgonzola 20 minutes room temperature 6. In a blender mix cheese and milk 7. Add Yogurt, hemp seed, CBD isolate, salt and pepper - mix well with a spatula 8. Serve with wings, celery and carrot s ck


POUTINE LINOTTE INGREDIENTS - 1 cup of fresh cheese curd - 5 potatoes cut in wedges - 1 tb spiced paprika - Salted herbs and cannabis dry leaves - Fresh peppermint - 4 to thc infused olive oil - 6 slices of bacon - 1 can or envelope of St. Hubert Pou ne sauce - 2 tb of cream 15% - 1 green onion minced - 2 tb rend wine - 1 tb Dijon mustard

STEPS Preheat oven at 425 F In a big bowl combine potatoes, herbs, pot leafs, pepper, olive oil. Spread on a baking sheet, cover with parchment paper, Bake 15 minutes, turn potatoes on side and bake 10 to 15 minutes more un l crisp and golden SAUCE In a small sauce pan combine sauce, cream, mustard, green onions and red wine, bring to a boil and reduce heat to low. Simmer 3 minutes and add CBD isolate, mix well. If in a envelope add 2 cup 1/4 of water Bake the bacon 25 minutes in the oven or un l crispy when reader cut it in small pieces ASSEMBLE 6.Put potatoes in a medium bowl, garnish with cheese and bacon and drizzle warm sauce over it, pepper and serve.


SAVOURY COOKIELINOTTE WITH STRAWBERRY SHERBERT

INGREDIENTS - 1 egg - 1/2 cup wheat flour - 1/4 ts baking soda - 1/8 ts salt - 1/4 cup mtl infused thc bu er - 2 tb brown sugar -1 tb hemp seeds - 1 tb Herbes de Provence - 1 cup fresh cheese curd chopped grossly - fleur de sel and hemp seeds to sprinkle -1 gram of dry flower of taste STEPS Preheat oven to 350F and cover a baking sheet with parchment paper. In a bowl, mix flour, baking soda, salt, hemp seeds and herbs, the Provence and dry cannabis. In a big bowl mix melted bu er, brown sugar, maple syrup and egg. Incorporate the flour mix and mix to make a dough. Add fromage en cro e, refrigerate for 15 minutes or as necessary. Makes 12 to 15 Cookielino es. Use around 1 tb per cookie. Put on a baking sheet and fla en a li le with a fork. Bake 10 to 12 minutes. Remove from the oven and sprinkle with fleur de sel and hemp seeds to taste. Let it sit a few minutes before ea ng them. Can be frozen.

STRAWBERRY SHERBET INGREDIENTS - 4 cups of fresh washed strawberries - 2 table spoon of water - 2tb of lemon juice - 1/3 cup of sugar - 1/3 cup of maple sugar - THC ncture to taste - CBD isolate STEPS Mix all the ingredients in a pot Bring to a boil mixing at the same me Let it simmer for few minutes un l the sugar dissolve and strawberries get tender . Remove from heat , let it cool down With the blender puree the mixture Freeze mixture in a shallow Pyrex container with Saran wrap in the bo om . A er 2 hours in the freezer cut it in cube and get it back in the blender for a smooth purée Back in the freezer and repeat the same steps 2 hours later. Ready to serve and fly away!


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