26 minute read

Emotions Do Aff ect Our Immunity: Optimism Pays

Emotions do affect our immunity: Optimism Pays

By Antony Chatham, M.Phil., MSW, LCSW We are constantly protected from invaders like bacteria, virus, fungi, and toxins, by our immune system. But can our thoughts and emotions affect our immune warriors? Yes.

A group of Harvard University scientists, the body’s ability to resist disease. The for example, found that in healthy people, brain influences all sorts of physiological simply recalling an angry experience from processes once thought not to be their past caused a six-hour dip in levels of centrally regulated. The researchers in the antibody immunoglobulin A (IgA) which the field found that there are effects of is the first line of defense against infection. psychological factors on many diseases

Psychoneuroimmunology (PNI), over the last 40 years, has already established that our thoughts affect our immune including rheumatoid arthritis, diabetes, hypertension, heart disease, and inflammatory bowel disease. system. PNI researchers study how One of the new findings in the field, our emotions and thoughts impact our as reported by Maier, S., professor of brain, hormones, and nervous system psychology at the University of Colorado, and also our immune system’s ability is that what we call sickness is an to protect us. In addition, these studies orchestrated process designed by the have pointed out that changes in the immune system to produce energy for immune and endocrine systems create fighting infection and to preserve energy changes in our nervous system which lead through behavior changes. Knowing that to changes in our emotions. The study signals from the brain--in particular the of the connections between the mind hypothalamus--trigger these sickness and the neural, immune, and endocrine responses, Maier and his colleagues set out (hormonal) systems is the core of the to tear apart the molecular machinery at discipline of psychoneuroimmunology. work. The first step was to figure out how The basic premise of this approach is the brain knows there is an infection in the the concept that the mind and body are first place. inseparable. It follows that stress affects 42 | hippocratesinst.org | Immunity and well-being Affective Immunology: is a relatively new interdisciplinary area of research dedicated to the study of the link between emotions, affects, and immunology. A number of studies have shown that both an imbalanced or improved emotional state can significantly influence the way our immune system works. D’Acquisto, F., University of Roehampton, London, finds a parallel between emotions and immune system - emotions and immune

responses are the ways in which a person

responds to the environment: they mirror each other, and they are dynamic and continuously changing. Further research, the author noticed, that living in a mentally and physically stimulating environment has a beneficial effect on the immune response. There are some current researchers, like Klæbo Reitan, of the University of Norway, who study the connection between

psychoses and the immune system. “We know that people with mental disorders are more susceptible than the general population to various inflammations in the body and to immune system disorders. This indicates that an interaction exists.” says Klæbo Reitan.

Autoimmune Diseases are the consequences of the inability of the immune system to distinguish the self

from the non-self. The function of the immune system is to protect the host from a universe of pathogenic microbes, such as bacteria, viruses, fungi, cancer cells, allergens, and so on. The immune system also helps the host eliminate toxic or allergenic substances that enter through mucosal surfaces. The key role of the immune system’s ability to mobilize a response to an invading pathogen, toxin, or Moreover, many retrospective studies, she adds, found that a high proportion (up to 80%) of patients reported uncommon emotional stress before their disease onset.

Long term stress is also shown to increase susceptibility to some cancers indicating that the immune system

failed: In a study, a Stanford University researcher, Dhabhar, F., has shown that long-term stress suppresses or dysregulates innate and adaptive immune responses by altering the Type 1-Type 2 cytokine balance, inducing low-grade chronic inflammation, and suppressing numbers, trafficking, and function of immunoprotective cells. Chronic stress may also increase susceptibility to some types of cancer by suppressing Type 1 cytokines and protective T-cells and increasing regulatory/suppressor T-cell function. and functions as an important integrator across physiological systems. They note that researchers are now beginning to understand the intricate relationships among the brain, microbiome, and immune system and how they work in concert to influence behavior.

People with mental health disorders

have lower immune response: Solveig M Klaebo Reitan of Norwegian University of Science and Technology points out in his research that people with mental disorders are also more susceptible to various inflammations in the body and to immune system disorders. He explains that the cells of the immune system communicate using signal molecules called cytokines. The cells of the nervous system send signals by means of signal molecules called neurotransmitters. The communication of

Negative feelings like stress, sadness, and worry cause a spike in the hormone cortisol, which in turn suppresses the immune system.

allergen, D’Aquisto mentions, is in its ability to distinguish self from non-self. The host uses both innate and adaptive mechanisms to detect and eliminate pathogenic microbes, and both of these mechanisms include self,nonself-discrimination. Autoimmune diseases are caused by the inability of our immune system to do this.

Chronic stress can cause autoimmune

problems: Many studies have shown that the experience of chronic stress can do this to the system. L. Stajanovich (Belgrade University), for example, explains that even though nearly 50% of autoimmune diseases may be caused by genetic, environmental, hormonal, and immunological influences, the other 50% of autoimmune disorders are attributed to physical and psychological stress. Depression can cause autoimmune neurotransmitters and cytokines are more problems: Christopher Pryce (University impaired in mentally challenged people of Zurich) noticed that up to 50% of than in the general population. patients with autoimmune diseases show an impairment of health-related quality of life and exhibit depression-like symptoms. The immune system not only leads to inflammation in affected organs, but also mediates behavior abnormalities including fatigue and depression-like symptoms. Chronic stress acts as a trigger for anxiety and depression by initiating changes in the hypothalamic-pituitaryadrenal axis and the immune system. Both experimental and clinical evidence shows that a rise in the concentrations of pro-inflammatory cytokines and A Gut Feeling: Microbiome-brain-immune glucocorticoids, as occurs in chronically interactions modulate social and stressful situations and in depression, affective behaviors: Sylvia, K. and Demas, contribute to the behavioral changes G. of Indiana University, have shown that associated with depression. social and affective behaviors of people are affected when the microbiome-brainimmune interactions are compromised. Recent work, according to them, suggests that the gut microbiome may also play a critical role in modulating behavior A Penn State University study (2018) showed that negative moods - such as sadness and anger - are associated with higher levels of inflammation and may be a signal of poor health. Immunity and well-being | hippocratesinst.org | 43

Inflammation is part of the body’s immune response to such things as infections, wounds, and damage to tissues. Chronic inflammation can contribute to numerous diseases and conditions, including cardiovascular disease, diabetes, and some cancers. Inflammation is an indicator of the connection of certain emotions to the immune system.

Researchers from Emory and Harvard Universities have shown that there is a strong correlation between inflammation in the

body and certain affective disorders. Heightened concentrations of inflammatory signals, including cytokines and C-reactive protein, have been described in posttraumatic stress disorder (PTSD), generalized anxiety disorder (GAD), panic disorder (PD), and phobias (agoraphobia, social phobia, etc.).

Being heard could improve immunity: A study published in Psychosomatic Medicine reported that HIV patients who wrote about their worries for 30 minutes a day, four days in a row experienced a drop in their viral load and a rise in infection-fighting T-cells. Another study, in the Journal of Consulting and Clinical Psychology, found that breast cancer patients who talked about their feelings regarding cancer had to schedule fewer doctors’ visits for cancer-related problems.

Positive Psychology focuses on strengths and positive characteristics instead of on psycho-pathology and what’s not working in people’s lives. Along with this approach there is a body of both research and clinical development to enhance your ability to cultivate the skills for creating positive emotional states and greater capability to enjoy life. “When it comes to our health,” says Seligman, “there are essentially four things under our control: the decision not to smoke, a commitment to exercise, the quality of our diet, and our level of optimism. And optimism is at least as beneficial as the others.” Scientists don’t yet fully understand 44 | hippocratesinst.org | Immunity and well-being

the biological mechanisms at work, but they know that negative feelings like stress, sadness, and worry cause a spike in the hormone cortisol, which in turn suppresses the immune system. We know tai chi has all sorts of benefits, and here’s one more: In research conducted at UCLA, 61 older adults took tai chi classes three times a week, while 61 others attended health education classes. At the end of four months, both groups received a dose of the shingles vaccine—and the tai chi group achieved twice the level of immunity. “It’s likely the meditation component that is causing the effect,” says study author Irwin, M., he adds, “Which means it’s possible other forms of meditative exercise, like yoga, would lead to a similar boost.” Sheldon Cohen, a psychology professor at Carnegie Mellon University found in a study that subjects who had the least variety

of social relationships were 4.2 times more likely to catch a cold

than those with strong social ties. In another of Cohen’s studies, he assessed 193 subjects to determine their level of positive emotions (including happiness, calmness, and liveliness). Again, he exposed participants to a virus—and found that people who scored low on positive emotions were three times as likely to succumb to the bug. What’s intriguing about this phenomenon, says Lara M. Stepleman, an assistant professor of psychiatry and health behavior at the Medical College of Georgia, is that “we all have the ability

to choose an optimistic mind-set. And with practice, we can get better at it.” It is possible to boost our immune function through mindfulness

meditation: a randomized, controlled study on the effects on brain and immune function of an 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees conducted by researchers in University of Wisconsin (and J Kabat-Zinn) showed: significant increases in left-sided anterior activation, a pattern previously associated with positive affect, in the meditators compared with the nonmeditators. They also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group; and the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine. Studies in the field of affective immunology suggests that adopting a healthier diet, developing a stable emotional intelligence, improving one’s socioeconomic conditions, and ceasing unhealthy habits such as drinking or smoking, have all been reported to be beneficial for both the emotional and immunological responses. The Life Transformation Program at Hippocrates Institute seems to integrate all these suggestions. Positive energy can create a stronger immune system; optimism pays!

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“It enriched my life in so many ways. Connecting with like-minded people, some of whom are now my friends for life, was a very important part for me. We learned a lot from the teachers as well as from each other. Being able to enjoy the food and property during our program was also amazing.

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Expert advice from the A-Team

Antony Chatham, M Phil, M Th, MSW, LCSW, is a Florida- licensed psychotherapist and a member of the National Board for Certified Clinical Hypnotherapists. He uses holistic traditions of healing and integrates psychology, philosophy and spirituality.

Andy Roman, LMHC, MS, RN, serves as a mind/body psychotherapist using and teaching feeling-centered, body-focused awareness tools. He conducts private sessions and facilitates the Healing Circle Therapy and Support Group.

ASK THE A-TEAM Send your questions to HOW@hippocratesinst.org I’ve heard a lot about positive thinking, and how important it is in the healing process. Isn’t that just being unrealistic? I don’t always feel so positive. Please advise.

We form whether we are predominantly a positive or a negative person by the time we are six years old. When our needs as a baby and a young child get met in a timely manner, we come to see the world, and people, as benevolent. We tend to live in a love-deficit, and unknowingly cultivate a predominantly pessimistic world view when we are ignored, neglected, or regularly punished as children; when we experience a mismatch between our needs for love, attention, and nurturing and what the world actually gives us. Unfortunately, a negative world view tends to find evidence to prove itself true, and we can end up being stuck in a grim jail of our own making, thinking that’s just the way it is, and that we’re victims of it all. Positive thinking at a conceptual level alone doesn’t undo that. That would be like garnishing a platter of rotten vegetables with fresh parsley. As good as the parsley may be, the other veggies still stink, and no matter how much you focus on the parsley, it doesn’t undo the reality of the entire plate. That doesn’t, however, mean we’re doomed. Our desire for positivity and our efforts to bring it in do make a difference. Using the parsley garnish metaphor, I say scrape the plate clean first. Dump the garbage, wash the plate, and then load up the fresh, new veggies you want. In other words: do your inner work first. Be ruthlessly honest about how you’ve come to be so negative. Make amends for all the hurts you’ve passed on. Grieve your losses. Forgive yourself, and others if you can. Your original innocence sits at your core waiting for you to wash everything else away. Then and only then do we snap out of our negativity and naturally recognize the deep and inherent goodness of creation. Positive thinking is our natural state. I’m saying: it’s not the world that needs garnishing, it’s us that need healing. That’s being realistic.

On my health journey,

I find myself repeating patterns of self-sabotage. I really want to live a healthy lifestyle, and stop hurting myself. How can I get off that cycle?

Following a healthy lifestyle program can help, but often, patterns of self-sabotage have deeper roots. Gestalt therapist, Fritz Perls, called persistent, recurring life patterns “unfinished business”. Unmet childhood needs, unexpressed feelings, and a warped sense of self do not automatically go away because we get older; they go in. They etch themselves into our neural pathways as habitual ruts of struggle and disappointment, and when we introduce those elements into our health journey, we unknowingly pollute our own way. The old self-doubts, fears, and limitations interfere with our new goals of health and happiness, and beg to be cleared up. That’s where therapy comes in, and why we offer emotional and psychological support services at Hippocrates. It’s more important to clean up yourself than it is to find the perfect program to follow. There’s no shortcut around your self-sabotage issues. Doing your inner work at a feelings level is the short cut that quickens the overall health journey.

Currently I am taking care of my ailing parents. I put on a lot of weight; I neglect my own needs and I don’t go out much at all. I feel guilty if I spend time on myself. Now I realize that I cannot continue to do this. I am exhausted. What do I do? In commercial flights we are all used • Set realistic goals: Break large tasks into to hearing, when preparing for take-off, smaller steps that you can do one at a time. that in case of an emergency we should put on Prioritize, make lists, and establish a daily our own oxygen mask first, before we help even routine. Learn to say ‘no’ to non-essentials. the children who may accompany us. A mother might feel guilty and might even say: “it’s really cruel”. But the reality is that a mother may not survive if she does not equip herself first. The same is true for all care givers. There is no need to feel guilty; taking care of you is part of the care itself. You will also be able to manage the weight issue once you start caring for yourself. • • Join a support group: A support group can provide validation and encouragement, as well as problem-solving strategies for difficult situations. It can also be a good place to create meaningful friendships. Seek social support: Make an effort to stay well-connected with family and friends who can offer non-judgmental emotional When someone chooses to come to Hippocrates support. Set aside time each week for Health Institute, either to improve health or to connecting. heal from a health challenge, we suggest the same thing: detox and then nourish with the best of foods. A care taker also should do this: get rid of stress and nourish body, mind, and spirit. • Get connected: Find sources of help in your community. Many areas have classes specifically about the disease your loved one is facing. Transportation, meal delivery, It is good to ask yourself: “Do I have signs of or housekeeping may also be available. care giver stress?” • Set personal health goals: Set goals to • • • • • Often feeling physically and mentally tired Feeling overwhelmed or constantly worried Sleeping too much - or too little Gaining or losing weight Feeling easily irritated or angry establish a good sleep routine, find time to be physically active, eat a healthy diet, and drink plenty of water. The following may specifically address the various areas of stress: • Feeling a lack of ability to enjoy activities Physical you used to enjoy • Eat a well-balanced diet • Feeling sad • Exercise. A brisk walk at least • Experiencing frequent headaches, bodily • Adequate rest/sleep pain, or other physical problems • Reduce or avoid stimulants • Exhibiting addictive tendencies to alcohol, • Take a break frequently, even if it is only 10 drugs, or even prescription drugs minutes at a time If so, then go for any or all of the stress Mental management strategies below: • Learn relaxation techniques • Focus on what you can do best for them: You may not be able to help with everything. Believe that you are doing the best you can and making the most appropriate decisions at any given time. • • • Listen to calming music Connect with and talk to someone daily or more frequently Stay social: connect with community and friendship groups • Ask for help when you feel the need: Assess your own requirements and ask for appropriate help from those responsible. For example, a friend may offer to take the person you care for on a walk a couple of times a week; a friend or family member may be able to run an errand, pick up your groceries, or cook for you. Spiritual • Disconnect yourself from the situation through meditation • Use prayer as an effective way to connect with something beyond • Attend religious rituals if they have meaning for you • Spend quality time with the one who you care for as a spiritual goal Immunity and well-being | hippocratesinst.org | 51

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Co-Director of Hippocrates Health Institute and author of numerous books, Brian travels the world giving lectures on the benefits of a raw and living foods diet and the Hippocrates Lifestyle. He is deplumed in Naturopathic Medicine and is a PhD in Nutrition. • Immunity, Immunity, Immunity • Lifeforce - Basis of Longevity and Exemplary Health • Q & A

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Co-Director of Hippocrates Health Institute, Anna has brought a European approach to healing to the Institute. She travels the world with Brian lecturing on the Hippocrates Lifestyle. She is deplumed in Naturopathic Medicine and a PhD in Nutrition. • Healthy Fat/Bad Fat • Immunity and the Gut/Brain Connection • Q & A

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