Humanitas Scientific Report Highlights 2018

Page 1

sCientifiC repOrt

highlights 2018


Humanitas

ReseaRch & UniveRsity hospital

Who We aRe humanitas is a highly-specialised hospital, research, and teaching center, which hosts humanitas University, an academic institute dedicated to medical sciences. Built around centers for the prevention and treatment of cancer, cardiovascular, neurological, autoimmune, inflammatory, and orthopoedic diseases – together with an ophthalmic center and a Fertility center – humanitas also operates a highly specialised emergency Department. the first italian hospital quality-certified by Joint commission international, humanitas is accredited by italy’s national health service. humanitas promotes health, prevention, and early diagnosis, by means of innovative and advanced outpatient healthcare facilities. appointed as an iRccs by the Ministry of health (an accreditation in the italian system that acknowledges institutions focused on excellence in clinical care and research), humanitas is a high profile, internationally well known center of excellence for immune systemrelated diseases, from cancer to rheumatoid arthritis. humanitas Research hospital is the flagship of a hospital group also present in Milan, Bergamo, turin, catania and castellanza (varese).

Our emplOyees

CliniCal aCtivity (yearly)

2,790 in total, with:

more than 40,000 admissions from italy and abroad 390,000 outpatients more than 50,000 eR patients 3.3 million lab tests 16,000 MRi 36,000 tc scan

693 physicians 231 researchers 1,386 nurses, technicians, biologists and others 480 client service and staff


scientiFic activities 4,061 = impact factor in 2017 560 professionals involved into research, among them: about 300 (principal investigators, junior principal investigators/staff scientists, postdocs and phD students, technicians) more than 200 clinicians 22 labs

4,061

20,000 m2 dedicated to research and education

776 600

563 421

2,253

363

1,587

1,878

2017

2016

2015

2014

2013

2012

896

2011

724

2007

2006

2017

2016

2015

2014

2013

2012

2011

2010

2009

2008

2007

2006

752

172

1,727

2009

197 160

3,218

2,627

2008

349

289

3,076

2010

416

3,506

636

Publications

Impact factor

number of Humanitas publications - years 2006-2017

total impact factor of Humanitas publications - years 2006-2017

Use this QR code to see the list of humanitas published papers

every year scimago Research Group analyzes yearly publications of approximately 5,000 research centers. according to the “excellence Rank” (the percentage of articles published in the first decile), humanitas ranks among the top 10% worldwide (315th out of 4,849 institutions) and in Western europe (141st out of 1,535 institutions), and among the top 5% in italy (8th out of 163).

Excellence

evaluatiOn Of Humanitas’ sCientifiC Output Scimago Excellence Rank 2015

100 90

Cold Spring

80 Inst. for System Biology

70

Dana Farber

60

Sloan Kettering CC

HUMANITAS

50

IIT

40

Cambridge S. Matteo Mayo Clinic Unimi

Politecnico MI

30

IEO H. San Raffaele

Policlinico MI

20 10 0

0

10

20

30

40

50

60

70

80

90

Q1 100

italian Universities Foreingn Universities other italian institutes italian hospitals

In Italy among the Top

5%

in Western europe and in the World among the top

10%

Excellence

Foreign hospitals 100 90 80 70 60 50


scientiFic laBoRatoRies

SCIENTIFIC DIRECTION AND REASEARCH LABORATORIES Director: Alberto Mantovani professor at Humanitas University

aDaptive immunity

meDiCal GenetiCs anD rna biOlOGy

analysis anD reHabilitatiOn Of mOtOr funCtiOn

mOleCular immunOlOGy

Junior principal investigator: Marinos Kallikourdis researcher at Humanitas University

principal investigator: Antonio Sica

clinical Research associate: R. Gatti professor at Humanitas University

muCOsal immunOlOGy anD miCrObiOta

applieD pHysiCs, biOpHysiCs anD miCrOfluiDiCs

principal investigator: Maria Rescigno professor at Humanitas University

principal investigator: Roberto Rusconi professor at Humanitas University

OnCOlOGy eXperimental tHerapeutiCs

Cellular anD mOleCular enDOCrinOlOGy clinical Research associate: Andrea Lania1 professor at Humanitas University

CliniCal anD eXperimental immunOlOGy principal investigator: Domenico Mavilio

CliniCal immunOlOGy anD autOimmunity anD metabOlism

clinical Research associate: Carlo Francesco Selmi1 Junior principal investigator: Simona Lodato professor at Humanitas University

153 86

paola allavena

83

Giorgio Walter canonica

81

antonio sica

64

silvio Danese

64

cecilia Garlanda

60

Massimo locati

60

Gianluigi condorelli

59

Gioacchino natoli

54

carlo Francesco selmi

54

Barbara Bottazzi

53

Maria Rescigno

51

Michela Matteoli

50

Matteo G. Della porta

47

antonio costanzo

43

Junior principal investigators: Barbara Cassani, Cristina Sobacchi, Francesca Ficara

carmelo carlo stella

33

andrea lania

30

inflammatiOn anD immunOlOGy in CarDiOvasCular patHOlOGies

stefano Duga

29

enrico lugli

27

Daniele catalucci

26

Domenico Mavilio

26

Barbara cassani

21

cristina sobacchi

21

sKin patHOlOGy lab

principal investigator: Antonio Costanzo1 professor at Humanitas University

transCriptiOnal anD epiGenetiC COntrOl in inflammatiOn anD CanCer

principal investigator: Enrico Lugli

principal investigator: Cecilia Garlanda professor at Humanitas University

tumOr miCrOenvirOnment

Junior principal investigator: Diletta Di Mitri

GastrOintestinal immunOpatHOlOGy clinical Research associate: Silvio Danese professor at Humanitas University

1

NATIONAL RESEARCH COUNCIL (CNR) Human GenOme anD meDiCal biOteCHnOlOGies

GenOmiCs Of HaematOlOGiCal maliGnanCies

clinical Research associate: Matteo Della Porta1 professor at Humanitas University

immunOpHarmaCOlOGy

principal investigator: Barbara Bottazzi

clinical Research associate: Gianluigi Condorelli professor at Humanitas University

leuKOCyte biOlOGy

principal investigator: Massimo Locati

Cold Spring

leuKOCyte miGratiOn

Dana Farber Sloan Kettering CC

IEO H. San Raffaele

siGnal transDuCtiOn in CarDiaC patHOlOGies principal investigator: Daniele Catalucci

principal investigator: Silvano Sozzani Inst. for System Biology

at January 1st 2018

silvano sozzani

translatiOnal immunOlOGy

eXperimental immunOpatHOlOGy

H inDeX2

alberto Mantovani

principal investigator: Gioacchino Natoli professor at Humanitas University

DevelOpmental neurObiOlOGy

HUMANITAS

prinCipal investiGatOr

principal investigator: Michela Matteoli professor at Humanitas University

principal investigator: Paola Allavena

Cambridge S. Matteo Mayo Clinic

clinical Research associate: Carmelo Carlo-Stella1 professor at Humanitas University

pHarmaCOlOGy anD brain patHOlOGy

Cellular immunOlOGy

IIT

principal investigator: Stefano Duga professor at Humanitas University

1

in addition to research, he works as a clinician

2

h index > 20. Fonte: scopus


inteRnational netWoRk collaboration at international level is fundamental for clinical practice. in the last years, collaborations with national and international top-ranking hospitals and the constant effort in implementing the most advanced technologies have led to outstanding results in the treatment of neoplastic, gastrointestinal, cardiovascular, neurological and immunological diseases.

International collaborations Europe: austria, Belgium, croatia, Denmark, France, Germany, Greece, ireland, netherlands, poland, portugal, spain, sweden, switzerland, United kingdom Rest of the world: argentina, Brazil, china, israel, Japan, singapore, Usa

Geographical distribution of foreign researchers at Humanitas From EU Countries (Total 17) Bulgaria croatia Denmark France Greece norway netherlands (antilles) poland Romania serbia and Montenegro spain United kingdom

1 1 1 2 1 1 2 2 1 1 3 1

Rest of the World (Total 7) 1 1 1 2 1 1

china (Macao) colombia ecuador iran Japan Russia

Italian researchers who returned after an experience abroad total humanitas University is a private non profit institution dedicated to medical sciences, founded in 2014. it is strictly interconnected with humanitas hospital, where clerkship activities take place.

International School of Medicine

43%

international students3 from

Europe (EU): cyprus, Finland, France, Germany, Greece, ireland, netherlands, poland, portugal, Romania, spain, sweden, switzerland, United kingdom Rest of the world: albania, angola, Bosnia-erzegovina, Botswana, Brasil, Bulgaria, canada, china, south corea, egypt, philippines, Ghana, india, iran, iraq, Fiji islands, israel, kenya, lebanon, Malaysia, nigeria, pakistan, peru, Russia, senegal, serbia, seychelles, singapore, syria, Usa, south africa, sudan, taiwan, thailand, turkey, venezuela, vietnam, Zimbabwe 3

students enrolled in the first year of Medicine

22


irCCs istituto Clinico Humanitas via Manzoni 56 20089 Rozzano (Milano, italy) phone +39 02 8224 2445 Fax +39 02 8224 5101 www.humanitas.it


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