Joint reconstruction strategy for structured illumination microscopy with unknown illuminations

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Joint Reconstruction Strategy for Structured Illumination Microscopy With Unknown Illuminations

Abstract: The blind structured illumination microscopy strategy proposed by Mudry et al. is fully re-founded founded in this paper, unveiling the central role of the sparsity of the illumination patterns in the mechanism that drives super super-resolution resolution in the method. A numerical analysis shows that the resolving power of the method can be further enhanced with optimized one one-photon or two-photon photon speckle illuminations. A much improved numerical implementation is provided for the reconstruction problem under the image positivity constraint. This algorithm rests on a new preconditioned proximal iterat iteration ion faster than existing solutions, paving the way to 3D and real-time time 2D reconstruction.


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