10 Best Companies in Digital Pathology Market 2023

An Overview

Salient Features of Digital Pathology

Progressive Insights AI in Pathology Market

Deciphex

Revolutionizing pathology through tech acceleration

Donal O'Shea Founder and CEO Deciphex

Beer Health and a better way of life.

Edit or’ s Note

Digital Pathology: Revoluonizing Disease Diagnosis and Treatment

Digitalpathologyisanemergingfieldthatcombines

cutting-edgetechnologywithmedicalexpertiseto improvetheaccuracyandefficiencyofpathology diagnosis.Itreferstotheprocessofdigitizingglassslides oftissuesamplesthataretraditionallyviewedundera microscope.Thisdigitalinformationcanthenbeanalyzed usingpowerfulsoftwaretoolsthatcanenhancethe visualizationofthetissueandprovideadditional informationthatisnotvisibleunderamicroscope.The benefitsofdigitalpathologyincludeincreasedaccuracyand speedofdiagnosis,improvedcollaborationbetween pathologistsandtheabilitytoanalyzelargeamountsofdata toidentifypatternsandtrends.

Thepotentialapplicationsofdigitalpathologyare numerous,fromearlycancerdetectiontopersonalized medicine.Oneofthemostpromisingareasofdigital pathologyisinthefieldofoncology Withthehelpof digitalpathology,pathologistscanaccuratelyidentify cancerouscells,classifytumors,anddeterminethestageof cancer,whichiscriticalindevelopingeffectivetreatment plans.

Anotherareawheredigitalpathologyismakinga significantimpactisthefieldoftelepathology

Telepathologyallowspathologiststoremotelyviewand diagnosetissuesamples,whichisparticularlyusefulin areaswhereaccesstopathologyexpertiseislimited. Telepathologyalsoenablespathologiststocollaborateand shareexpertiseacrossgeographiclocations,whichcanlead tobetterpatientoutcomes.

Inconclusion,astechnologycontinuestoadvanceandthe demandforpersonalizedmedicinegrows,wecanexpectto seeevenmoregroundbreakingdevelopmentsinthedigital pathologyspace.

InsightsCare'slatesteditionof10BestCompaniesin DigitalPathologyMarket2023introducesyoualltothe companiesthatarerapidlyevolvinginthefieldhavingthe potentialtotransformthewaytodiagnoseandtreat diseases.

Hope you have an informative read!

-PoojaShah

10 Best Companies in Digital Pathology Market 2023

Description Featuring Person Company

AXON Diagnostics

Axondiagnostics.com

Bionovation Biotech Inc. Bionovationimc.com

CliniSys Sunquestinfo.com

Paul Cornell General Manager

Axon Diagnostics offer a suite of solutions to support the needs of modern day diagnostic imaging services, using nextgeneration technology and a purpose to disrupt the global teleradiology and pathology markets by doing things differently, to support happier lives for clinicians and help deliver better diagnostic care for all.

Yuefeng Yin CEO

Chad Meyers Vice President of Product Management & Strategy

Deciphex Deciphex.com

Donal O'Shea Founder and CEO

Bionovation Biotech Inc. is aimed for using a significant technological innovation to improve digital imaging in pathology

Clinisys is a global provider of informatics software and expertise to support diagnostic testing across healthcare, life sciences and public health.

Deciphex is focused on the development of software applications for preclinical/toxicologic pathology that improve productivity and help pathologists focus on the critical content

Imsight Technology Imsightmed.com

Huangjing Lin Chief Technology Officer

Imsight Technology is training AI to analyze medical images for faster and more consistent disease detection using award winning deep-learning techniques.

KUB Technologies Kubtec.com

Vikram Butani CEO KUB Technologies is a leader in specimen imaging systems and margin management technology.

Objective Imaging Limited

Objectiveimaging.com

Don Laferty President

Objective Imaging is the market-leading provider of automated digital microscopes for use in digital pathology and remote diagnostic applications.

OptiScan Optiscan.com

Ultivue, Inc. Ultivue.com

WSK Medical Wskmedical.org

Camile Farah CEO Optiscan is the global leader in real-time non-destructive digital microscopic imaging for medical applications.

Jacques Corriveau President

Ultivue develops innovative reagent-based solutions that maximize the biological information available from cells and tissue samples.

Marius Wellenstein Co-founder and COO

WSK Medical is passionate about assisting clinicians to transform the diagnosis and treatment of cancer through Artificial Intelligence (AI) solutions.

Donal O’Shea Founder and CEO Deciphex

CoverStory

Deciph Deciphex

In2022,therearefewerpractisingpathologists,who Ihavetoperformmorefrequentandmorecomplex reviews.Anybusinessthatcanspeedupprocessesand simultaneouslyenhanceconfidenceinoutcomesmustbe includedinourlistofthe10BestCompaniesinDigital PathologyMarket2022.

Revoluonizing pathology through tech acceleraon

Let’s Read More!

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By building digital networks, Deciphex provides real-time access for international referring laboratories and organizations to the quality pathology services they need.

In2022,pathologyhassufferedaperfectstorm.Thereare fewerpractisingpathologists.Theyhavetoperformmore frequentandmorecomplexreviews.Delaysjeopardize drugdevelopmentprograms.Hastejeopardizespatient outcomes.

Anybusinessthatcanspeedupprocessesand simultaneouslyenhanceconfidenceinoutcomesmustbe includedinourlistofthe10BestCompaniesinDigital PathologyMarket2022

TounderstandwhatDeciphexhasbeenabletoachieve,and howitgothere,InsightsCaresatdownwithDonalO’Shea, FounderandCEOofDeciphex.

In20yearsinthefield,Donalhasdedicatedhisjourneyto harnessingtechnologytoempowerinnovationsinmodern healthcare.Afewyearsago,hesetouttoassembleateam thatshareshisvisionofmakingasignificantimpactonthe healthcaresector.

TheRoutetoInnovation

DonalO’SheaandMarkGregsonestablishedDeciphexin 2017afterrecognisingashortcominginthepathology sector.Itstruckthemthatthecommonone-size-fits-all approachtodigitalpathologywasinadequate.

DonalandMarkwereespeciallyconcernedthatworkflows standardizedacrossallsegmentsofthemarketplace.They believedthiswasunhelpful,whenneedsacrosssectors wereverydifferent.

Ingrainedpracticeswerefailingtomitigateshortagesof pathologyservices.Theyfeltthatenablingextraorganizationalcollaborationscouldalleviatetheissue,and beofmuchgreaterbenefitinsupportingorganizations.

“TheadventofAIandavisionofanAI-integrated workflowforpathologyserviceenhancementwasvery closetoourthinking,”statedDonal.

Pathology’sCriticalRoleinPositivePatientOutcomes

“Certaintyandreliabilityarevitalaspectsofpathology. Thishasbeenproventimeandagain.Morethan70percent ofalltheclinicaldecisionsmadearoundapatient’s diagnosisinvolvepathology,makingitanintegralpartof thehealthcaresystem.

able to connect dynamically with an external landscape of telehealth service providers such as Deciphex.

Evenwithgradualadvancements,thisapproachwas inadequatetomeetnumerousemergingchallenges.Chronic issuesinPathologysuchasburgeoningpatientwaittimes, recruitment,demandforexpertiseanddiagnostic complexitynecessitatedaninnovativesolutionforoptimal patientcare.”

DemandingTimesDemandIncreasedProductivity

Deciphexsawtheneedtoimprovepathologistproductivity –andrecognizedDigitalPathologyandAIasthesolution.

“Theuseofdigitalpathology(workloadbalancing)and artificialintelligence(processacceleration)willbeacritical tosolvingcurrentshortfallsinpathologyservices.”

Today,Deciphexisarevolutionarydigitalpathology companyattheforefrontofthisinnovativetechnology

Deciphexnetworkswithpathologistsfromallcornersofthe globetodrivehigh-qualityandefficientreporting,allwhile addressingthepathologyproductivitygapwithdigital pathologyandAI.

TransformingPathologyByEmpoweringAI

Donalstated,“TheDeciphexvisionistotransformorreplatformpathologyusingDigitalPathologyandAIwithan aimtodeliverAI-empoweredpathologyservices,where andwhentheyareneeded.”

Theuseofdigitalpathology(workloadbalancing)and ArtificialIntelligence(processacceleration)willbea

It is critical for healthcare providers to be

criticalpartofthesolutionforshortfallsinpathology services.

Deciphexisattheforefrontofthisrevolution,networking withpathologistsfromallcornersoftheglobetodrive high-quality,efficientreportingwhileaddressingthe pathologyproductivitygapwithdigitalpathologyandAI. TheresultofthisfocusisthePatholytixplatformand Diagnexiaonlinepathologyservice.

Patholytix

Integrate Workflows, Accelerate Research – The Single Go-ToPlatformforResearchPathologyProfessionals

Patholytixistheindustry-leadingdigitalpathology workflowandintegratedAIplatformforResearch Pathology TheleadingCROsandpharmaceutical companiestrustPatholytixforhandlinghigh-volumedrug safetypathologystudies,providingacompleteGLPcompliantworkflowwithintegratedAIscreening capabilities.

Diagnexia

RemoteExpertSubspecialtyPathologyonDemand

Diagnexiaisanonlineclinicalpathologydepartmentby Deciphex.Diagnexiaprovideson-demandaccesstoremote

subspecialtypathologistsforprimarydiagnosticsand secondaryconsultservices,supportingtheaccelerationof diagnosticturnaroundtimesanddeliveryofthehighest qualityofpatientcare.

FocusonDeliveringHigh-ValueServices

Ratherthansimplyservicingenterprisedigitalpathology needs,Deciphexisallaboutconnectingorganizations. Deciphexfocusesonbuildinghigh-valueextraorganizationalnetworksofserviceproviderswhocan delivervaluetostakeholdersindireneedofpathology serviceexpansion.

Donalasserts,“OurAI-empowerednetworksmeanour extra-organizationalnetworksaredeliveringgreater efficiencyandqualitythannon-AIempowered equivalents.”

ExpandingJurisdictionbyIntegratingDigitalization

Bybuildingdigitalnetworks,Deciphexprovidesreal-time accesstoqualitypathologyservicesforinternational referringlaboratoriesandorganizations.Client organizationscanexpandaparticularjurisdiction’s pathologycapacityby‘digitallyrepatriating’pathologists whoareregisteredtopracticeinthatregionbutwholivein adifferentcountry

ExceptionalLeadership

Donal is an experienced corporate officer in the technology and diagnoscs sectors, having 20 years of business leadership experience from start-up through to large corporate enterprise. Donal has considerable M&A experse. He has founded three companies and has senior management experience in Slidepath, Genex, Leica Microsystems and Leica Biosystems.

“Inresearchpathology,weareenablingconnectivity betweenPharma,CROs,andanexternalConsultant networktosmoothoutthelogisticsofmovingphysical researchstudiesbetweenstakeholders,savingweeksinthe qualificationofdrugsafetyinPharmatrials,”addsDonal.

EmphasisonDigitalization

Itiscriticalforhealthcareproviderstobeabletoconnect dynamicallywithanexternallandscapeoftelehealth serviceproviderssuchasDeciphex.Theadventofhighqualitydigitalpathologyscanningequipmentallowsthese digital‘sockets’tobecreatedintheclinicallandscape.

TheDiagnexiasolutionempowerslabstoproduceadigital substratethatcanberapidlyandsecurelyoutsourced,with collaborationandinvolvementofClinicalISandITteams toadjudicatethequality,securityandintegrityofsuch telehealthsolutions.

SavingLivesbyAcceleratingDrugDevelopment

“Thisisanamazingsectortoworkin,”statesDonal.“We aresomotivatedandexcitedbythequalityofmeaningful problemswearesolvingfortheclinicalandresearch communities.”

HebelievesthatthroughthemediumofDeciphex,theyare genuinelysavinglivesbyacceleratingdrugdiscoveryand byprovidinghigh-quality,timelydiagnosesforitsclinical partners.

FuturisticApproach

DeciphexrecentlylauncheditsDiagnexiaclinicalconsult serviceintheUSlastfallofferingaccesstoafantastic rosterofworld-renownedpathologists,whichiscomparable ifnotexceedingthequalityofanysingleinstitution’steam.

Beyondthis,itwillberapidlydevelopingitspresenceinthe UKandCanadaandexpandingmarketcoverageinthe MiddleEast.

Axon Diagnostics

Withtheadventofdigitaltransformationin healthcare,visualinterpretationofcellular biologycapturedinimagesprovidesdatabackedanswersforpeoplewhoseekananswertothe question,"What is wrong with me?"beforetheydecideon thebeststepstotakeinattendingtotheirhealthconcerns. Combiningthepowerofhumanintelligenceanddigital technology,thereisanimprovedandcomprehensive understandingofbodilyfunctionsandsystems,topromote goodhealth,throughadequatecureandpreventionof relapse—thedemandforqualifieddiagnosticshasincreased withinthehealthcaresector,ofthosewhocanusedigitized diagnosticabilitiesasatoolforexcellenceinthisregard.

Cliniciansarereliantonaccuratediagnosticsthathelp reducehumanerroraswellasproduceprecisediagnostic resultsinashortturnaroundtime.Theaccuracyofdata,and speedofdeliveryhelpinimprovingthetreatmentmeasures fortheirpatients.Butwithconcernssuchasashortagein supplyoftechnicallyadvancedpathologies,accessto accuratediagnosticsisaconcernthatkeepsthehealthcare sectorfrommeetingthedoctor-patientobjectivesfor accuratedata,hencebelow-partreatmentbecomestheorder oftheday

AxonDiagnosticsisadigitizedsolutionthatamplifiesthe processofdeterminingwhichdiseaseorconditionexplains aperson'ssymptoms.Providingadequatesolutionsby enablingdoctorstoofferanexpertdiagnosis,regardlessof anygeographicalregionorlocationtherebyfacilitatingthe instantavailabilityoftrainedspecialists24hoursaday,365 daysayear Theyaresettodisrupttheglobalradiologyand pathologymarketsthroughtheirteleradiologytechnology advancementsandmodern-daydiagnosticimaging technologies.

Supporting Better Diagnostic Care for All

Theircareprovidersaretrainedtoleveragetechnologyto attaintheconfidencethattheyrequireindiagnosingtheir patients.Thisinturnimprovesthequalityofpatients'lives andprovidesbetterdiagnosticcareforall.

InaninterviewwithInsightsCare,PaulCornell,General Manager,walksusthroughAxonDiagnostics'technology anditsroleinturningthedirectionofdiagnosticsaround.

Following are excerpts from the interview:

Kindlytellusthesourceofinspiration.Whatledyouto ventureintothefieldofdigitalpathology?

Asateam,wehaveextensiveexperienceinteleradiology andtheprocessofdigitizingradiologyacrossregions. Therearelotsofelementsthatcanbeappliedtotheworld ofpathologytomodernisehowpathologyishandledinthe UK.Ourcurrentbusinesslendsitselfverywelltobenefiting thepathologymarketanditsrapiddigitizationofit.

Briefusaboutthecompanyandshedsomelightonyour operationsthereincontributingtothecompany's growth.

ThecompanywasconceivedinNovember2020witha missiontodisrupttheUKandglobaltele-diagnostics (radiologyandpathology)marketbydoingthings differently Weprovideourcustomerswithasuiteof servicestosupportthedeliveryofcost-effectiveandhighly efficientdiagnosticservices.Weuseaproprietaryand globallyunique"Netflixstyle"technologywhichallowsus todeliverservicesatrapidspeedandhighlysecure.Weare nowjustovertwoyearsoldandourgrowthhasbeen unprecedentedinthismarket.

Canyouelaborateuponthecorevalues,mission andvisiononwhichthecompanyisbuilt?

OurmissionistosavetheNHSmoney,improvethe workinglivesofcliniciansandsupportbetter diagnosticcareforall.

Ÿ ClinicallyLed

Ÿ Collaborative

Ÿ PeopleFocused

Ÿ InnovativeandAgile

Ÿ FairandSociallyConscious

Whatdiagnostictoolsdoesthe organizationfindtobeessential inconductingitspathology operations?

AxonDiagnosticsisallaboutfirst disruptingthenormtofindbetter waysofdeliveringcareunder challengingconditions.Wehave

Paul Cornell General Manager AxonMedical Ltd trading as Axon Diagnostics

AI is a widely talked about area of innovation and development within healthcare and we believe that within diagnostics this will become a significant tool to improve outcomes. We are working closely with a number of partners in the AI and technology space to ensure that we can provide our customers with the best tools out there to improve efficiency and clinical outcomes.

comeupwithinnovativetechnologyandsolutionsto addressthesechallenges.Butasoneofourcorevalues suggests,westrivetocontinuetoinnovateandremainagile inouroperationsallowingustopivotquicklytoevolve withthechangingdemandsofthemarket.

AIisawidelytalkedaboutareaofinnovationand developmentwithinhealthcareandwebelievethatwithin diagnosticsthiswillbecomeasignificanttooltoimprove outcomes.Weareworkingcloselywithanumberof partnersintheAIandtechnologyspacetoensurethatwe canprovideourcustomerswiththebesttoolsoutthereto improveefficiencyandclinicaloutcomes.

Whatadvicewouldyouliketogivetobudding entrepreneursandenthusiastswhodesiretoventure intothefieldofdigitalpathology?

Iwouldsaythatthethreemostimportantthingstokeepat theforefrontofyourmindare:

Ÿ Regardlessofthedecisionthatyoumakefromdesignto commercialization,alwaysreverttothinkingaboutthe patientbenefit.

Ÿ Beforward-thinking.Thinkaboutdevelopingthe servicefortomorrowonaplatformthatisagileand allowsyoutokeepupwiththerapidaccelerationseenin thetechnologyspace.

Ÿ Workcloselywithyourendusersfromanembryonic stage.Manyinthepasthada'builditandtheywill come'attitudeandhavefailedtodelivereffective solutionstothereal-lifeproblemfacinghealthcare.

Howdoyouenvisionscalingyourorganization's servicesandoperationsin2023andbeyond?

Wehaveambitiousgrowthplansandareengagingwith teamsinternationallytoutiliseourtechnologyandsolutions tohelpwiththechallengesfacingotherhealthcaremarkets acrosstheworld.

Whataresomeofthetestimonialsorrecognitionthat accuratelyhighlightyourorganization'spositioninthe market?

NHSGreaterGlasgow&Clydeisdelightedtohave engagedAxonDiagnosticsasanoutsourcedreporting house.Frominitialengagementtoimplementation,the

processhasbeenseamlessandmanagedinavery professionalmanner Thequalityofserviceisexcellent.

-MaryMcKee,GeneralManagerImaging,NHSGreater Glasgow&Clyde

Digital Pathology Salient Features of

Digitalpathologyisaconceptthathasexistedfor

morethanacentury,butonlyinthelastdecade haveadvancesintechnologyallowedforits widespreadadoption.Thedigitalpathologymarketis growingallthetime.TheglobalmarketwasvaluedatUSD 767.6millionin2019andisexpectedtogrowatarapid rateof11.8CAGRbetweennowand2027.

The continued growth of this market is strongly linked to the many features that benefit the scientific community. The following are the specific features:

ShorterWaitingTimes

Thankstohighperformance,fastfull-slidescanners,and supportingsoftware,thetimefromcaseregistrationtothe finalreportissignificantlyshorter

Digitaltoolsaccelerateworkflowthroughautomation, fasterandeasieraccesstopatientandcaseinformation,and improvedcollaborationbetweenpathologists,evenin physicallydistantlocations.Thisshortensthedeliverytime.

ImprovedPrecisionofDiagnosis

High-resolutiondigitalslidesprovidethepathologistwith betterimagequalityandmoredetailthroughmultiple viewingoptions,grouplabelingandZ-stackor3Dimaging. Itisalsoeasiertousedigitalslidesofpreviouscasesfor comparativeanalysis.Thenumberoferrorsisreduced thankstothebarcode-basedidentificationofslides.In addition,digitalimageanalyzershelptoautomateand quantifyfindings,reducingoreliminatingmanualwork (suchasmanualcellcounting)andprovidingamore objectiveandfastercontributiontofinaldiagnosis comparedtotraditionalmicroscopy

Non-PatientsEfficiencyBenefits

Inadditiontopatientbenefits,ahospitalhasseveralbenefits thatcanbemeasuredrelativelyeasytobuildabusiness modelandjustifyinvestmentindigitalpathology The study,conductedinalargeUSpathologylaboratory processingmorethan200,000casesayear,showedsavings ofabout$18millionoverfiveyears.Anotherstudyinalab intheUKthatprocessed80,000samplesayearfoundthat evenifproductivityimprovedbyjust10%,theproject couldfailinthesecondyear.

ImprovedPathologyEfficiency

Pathologistscanworkfasterandmoreefficientlywith digitalpathologytools.Bothslidereviewandimage analysisbecomefasterandmoreaccurate,andtreatment errorsaresignificantlyreduced.Thankstothescreen sharingandchatfunction,internalconsultationsarealso easierandfaster.Thesebenefitsensureafasterandmore efficientpathologyworkflow

ReducedCostofInternalHandlingofGlassSlides

Theintroductionofdigitalpathologysignificantlyreduces theadministrationandmanagementoftheadministrative staff.Noonehastomanuallysortthroughslides,handthem offtoapathologistandretrievepastcasesfromtheslide archive.Thissignificantlyreducestheadministrative burdenonsupportstaff.

RoleofDigitalPathologyinShapingtheJobMarket

Digitizationhasshapedemploymentandprofessions,and facilitatedglobalization.IfDigitalPathologydoeschange,

itwouldbenaivenottoassumethatitwillshapethejob marketforpathologists.TowhatextentAIcanreplacethe humanpathologistremainstobeseen.

Forinstance,astudybyMcKinseyassessedthecurrent potentialforautomationinAmericanoccupationsand foundthatthelowestpotentialisinoccupationsthat "manageothers"at9%ofworkingtimeandexpertiseat 18%,thelatterbeingapathology.Attheotherendofthe scale,theauthorspredicteda78percentautomation potentialinvolvingmanuallabor Thestudyalso emphasizedthatthepotentialforautomationwasonlyone factoraffectinghumanreplacementbyautomation.Other factorsincluded:thecostofautomation,therelative scarcityandcostofskilledreplacementworkers,the benefitsoflaborreplacement(increasedquality),andfinally regulatoryandsocialacceptabilityconsiderations.

Therefore,technologicaldevelopment,personnelshortage inpathologyandqualityimprovementthroughDPshould beconsideredthemaindriversofautomationpressureson theprofession.Atthesametime,low-riskprofessionsthat applymedicalexpertisehavebeenevaluatedfromthepoint ofviewofautomation.

WrappingUp

Willartificialintelligencemakeapathologist'sdayless stressful?CombinedwithAI,DigitalPathologycanhelp withtasksthataredifficultforahumantoevaluate(suchas quantification).Incontrast,AImaygenerallybegoodat evaluatinghumansinarelativelysimpledomain,suchas detectinglymphnodemetastases,andmayfailwhenthings becomedifficultforbothhumansandAI,i.e.,complexand challengingassessmentsthatrequiregeneraljudgment.This situationcanleadtopathologistshavingtoperformvarious complextaskswhileartificialintelligenceperformssimple tasks.

WeexpectthatthefutureworkingdayofaPathologistwill beevenmoredemanding,butalsomoreinteresting. Althoughautomationhasadvanced,ensuringoverall reliability,qualitycontrolandmedicalaccountability remainstheresponsibilityofthehumanprofessional,asis alreadydoneinhighlyautomatedspecializedmedicalfields suchaslaboratorymedicine.

-SaloniAgrawal

HuangjingLin CTO

ImsightMedical TechnologyCo.,Ltd.

Imsight Medical Technology Co., Ltd.

Assisting Doctors by Providing Higher Accuracy in Diagnosis

Our AI-based products can help to significantly increase the sensitivity of screening, as well as reduce 70% workload via negative sample elimination.

Pathologists can focus on the suspicious positive cases that our system detects and make the most of their expertise.

For patients, they can access better and more accurate clinical service with a shorter diagnosis cycle.

Themainapplicationscenariosincludeoncology,obstetrics andgynaecology,ophthalmology,pathology,medical imaging,andradiotherapy.Wehavebuiltupscientific researchandclinicalcooperationwithhundredsoftop-tier hospitalsinChinaandabroad,suchasPekingUnion MedicalCollegeHospital,PLA309Hospital,WestChina HospitalofSichuanUniversity,HongKongPrinceofWales Hospital,ShanghaiTongjiHospital,ShenzhenPeople's Hospital,SunYat-senUniversityAffiliatedCancerHospital, etc.

IwasleadingtheR&DdepartmentofImsightandmanaged tolandaseriesofAIproducts,suchasCervical-Sight® (cytology),Breast-Sight®(pathology),DR-Sight® (radiology),Lung-Sight®(radiology),etc.Ihavealsoled R&Dteams,publishedmorethan20+papersinthefieldof digitalpathology,applied26US/Chinapatternsandwon 20+internationalAIchallengesinthefieldofmedicine.

Canyouelaborateuponthecorevalues,missionand visiononwhichthecompanyisbuilt?

ThecorevaluesofImsightarehigheraccuracy,less misdiagnosis,alleviatingtheworkloadandmakingthe diagnosiseasier WearestrivingtobecomeAIempowers theHealthcareIndustryleaderandprovidehigh-qualityAI solutionstoassistdoctorseverywhereintheworld.

Inwhatwaysdothecompanyserviceshelpthepatient populationinresolvingtheirhealthneeds?Howare thesedifferentfromotherformsofcarethattheyreceive ordonotreceiveingeneral?

Forstarters,taketheexampleofcervicalsmearscreening. Cervicalsmearscreeningisaverytedious,laboriousand experience-dependenttask,whichrequiresanexperienced cytologisttospendfivetotenminutesforacarefulreview undermicroscopy.Atypicalsmearcontains20,000-50,000 cellsanditisunrealisticforacytologisttothoroughly reviewallofthecellswithsubtlechanges.

Anotherdilemmaistheshortageofpathologists,which mightresultintheoverburdenedworkloadintheir diagnosticroutineandamisdiagnosisrateisinevitable(2030%inasinglescreeningoccasion).

Cervical-Sight®systemcanhelptosignificantlyincrease thesensitivityofscreening,aswellasreduce70% workloadvianegativesampleelimination.Pathologistscan focusonthesuspiciouspositivecasesthatoursystem detectsandmakethemostoftheirexpertise.Patientscan accessbetterandmoreaccurateclinicalserviceswitha shorterdiagnosiscycle.

Whatdiagnostictoolsdoestheorganizationfindstobe essentialinconductingitspathologyoperations?

Inbreastcanceroperation,lymphnodemetastasisdetection (Breast-Sight®)isveryessential.Surgeonsneedtomake theirsurgicaldecisionbasedonthediagnosticconclusionof thestagingofthemetastasis.Ourcompanyensuresto providethesetoolstoeasetheirconcernswhenconducting pathologyoperations.Otherdiagnostictoolslike immunohistochemistry,alsoplayanimportantrolein pathologyoperations,andwecanprovidethesame.

Whatendeavorsistheorganizationcurrentlypursuing toimproveitspathologymeasuresforpatients?

WeaimtodevelopAIsystemsbasedonclinicalandpatient requirements.Webuiltupacloud-basedplatformfor pathologyecologywithsmarterAIempoweredtoresolve thedilemmaofthemisallocationofclinicalresourcesinthe world.Atpresent,wearetryingtoimprovethepathology ecology,ensuringthepatientsinthebasic-levelhospital stillcanaccessthetop-tierdiagnosticservice.

Whatadvicewouldyouliketogivetobudding entrepreneursandenthusiastswhodesiretoventure intothefieldofdigitalpathology?

Digitalpathologyisapromisingindustrywithabright future.Thisisaninterdisciplinarysubjectandrequires cross-sectionknowledgefromcomputerscienceand pathology Thefieldisalsohighlyrelatedtohumanlife. Practitionersshouldhaveaweoflifebeforetheirventure intothisfield.Besides,researchandunderstandingdepthis essentialforapersontoventureintothisfield.

Howdoyouenvisionscalingyourorganization's servicesandoperationsin2023andbeyond?

Ataproductlevel,wearecontinuingtopolishourAI models,andexpandingourproductpipeline.Atthe marketinglevel,weareseekingopportunitiestoexplore overseasmarketing.

AI in Pathology Market

Progressive Insights

Theroleofartificialintelligence(AI)inthemedical

fieldisconstantlygrowing.Artificialintelligence promisestorevolutionizepatientcareinthecoming years,withtheaimofoptimizingindividualizedmedicine andadaptingittospecificpatients.Medicinehasbeenslow toadoptartificialintelligence.Somedepartments,suchas radiology,havebeenquicktoadoptAI.Others,suchas pathology,areonlynowbeginningtouseAIinclinicaluse.

Pathologyisoneofthemostimportantareasofhealthcare. Itstudiestheeffectsandcausesofdiseaseandinjury. Pathologistscombinescienceandmedicinetostudyand diagnosevariousdiseasesandinjuries.Forexample,a pathologistexaminesalumponsomeone'sarmtocheck whetherthepatienthascancerornot.

Inaddition,thepathologysectoriscurrentlyfacingvarious challengessuchasincreasingdemandandalackof manpower.However,digitalsolutionssuchasAIandML arehelpingtoovercomethesechallenges,enabling improvementsinmanyareasoftheindustry

Let’s dive in to understand how AI is improving pathology.

MoreAccuracy

Humanshavelimitedaccuracyandtheabilitytoanalyze andprocessthings.AI/MLcanallowthepathologistto overcometheselimitations.Someofthekeytasksofa pathologistarediseasedetection,classification, segmentationandquantification,andAI/MLmodelscan helpimprovetheaccuracyofthesetasks.

Forexample,anAI/MLmodelcombinedwithcomputer visioncanhelpstudycellstakenfromacoreneedlebiopsy oftheprostatewithhighaccuracy.AI/MLmodelsensure thatalllayersandpixelsofthesampleimageareanalyzed todetecteventhesmallesttumorsorabnormalities.

ThefirstthingthatAIshouldchangeinpathologyisto makethediagnosticprocessfasterandmoreaccurate.This isbecauseAIprogramsrelyheavilyondeeplearningto understandcompleximagesandpatternsandimitate humans.

Therefore,thediagnosticprocessofartificialintelligencein pathologyisfasterandprovidesbetterqualityinformation aboutbio-specimens.Thetimesavedcanbeinvestedin savingthepatient'slifebyplanningbettertreatmentand doingmoreresearchrelatedtothedisease.

MoreProductivity

Inadditiontomoreaccurateanalysisofmedicalimages, artificialintelligencehelpspathologistsincrease productivity.Withthehelpofartificialintelligence,the pathologysectorcanmeettheincreaseddemandofthe currentworkforceandsolvetheproblemofthelackof pathologists.AIcanprovidethefollowingbenefits:

Ÿ Fewerhumanerrorsinsamplehandlingandprocessing

Ÿ Betterworkloadmanagementforpathologists

Ÿ Fasterturnoverofpatients

Ÿ Qualityassurance

Ÿ Automaticquerysubmissionandautomaticreportingof certaintests

PatientManagement

AnotherapplicationofAIinpathologyispatientcare.Ina digitallab,AIsystemscananalyzepatient-relateddataand medicalimagesandforwardthemtoapathologistfor furtherconsultationbasedondefinedcriteria.

Theautomatedsystemcan:

Ÿ Checkthedigitalmedicalimagesattachedtothecase

Ÿ Identifycaseshighlightedinstatistics

Ÿ Confirmtheorderedtestsandmakesuretheymatchthe sampletype

Ÿ Thiscansignificantlyincreaseworkefficiencyandwork timeinthelaboratory

QualityControl

Oneoftheproblemsofpathologicalimageanalysisis subjectivity.Analysisandresultscanbeseendifferentlyby differentpeopleorbythesamepersonondifferentdays. However,whenitcomestoartificialintelligence,itdoesnot havebaddaysandtheanalysisresultsremainconsistent. Thisprovidesanopportunitytoreducehumanerrorsin diagnosisandensuretheaccuracyandconsistencyof results.

SoevenifwegivetheAI100,000samplesadayto analyze,itwillproduceconsistentresultsandtherewillbe nodeviationfrombasiccommandsoron-the-ground learning.

DiagnosingDiseases

WhilediseasediagnosisisatthecoreofAIinpathology, anotherimportantbenefitofusingAIindiagnosisisrelated tounderstandingdiseasebiology.AIcananalyzedigital pathologysamplesatthemacro-andmicro-levelsand identifypatterns,groupsofcells,orothercharacteristics thataresometimesnotvisibletothehumaneye.

Asaresult,itcanhelpunderstandthebiologyofvarious diseasesandfindtreatmentsandcures.Inaddition,artificial intelligencecanhelpdetectchangesintissuesampleseven atthesmallestlevel.

WrappingUp

Asthehealthcareindustrycontinuestoevolve,medical professionalsmuststayabreastofnewtechnologiesand toolsthatcanimprovepatientcare.AIhasalreadybeen adoptedinseveralhealthcarefields,includingradiologyand manyothers.Becauseitcansavelivesandmakediagnoses faster,itwillbeanimportantpartofhealthcareforyearsto come.Also,itmaynotcompletelyreplacethedoctorinthe shortterm,asitcancertainlyaddvalue.

-SaloniAgrawal

KUB

Technologies, Inc.

Empowering Surgeons to Reduce the Number of Re-excision Surgeries

Thankstotechnology,thehealthcaresectoris progressingatarevolutionarypace.Theadvanced technologyandmedicalgadgetsbeing manufacturedareenablinghealthcareprofessionalsto increasetheirsuccessratesinoperationrooms,research, andthetimelydevelopmentofvaccines,drugsand medicines.

Nowthathealthcarehassubstantiallymodernized,thereis optimistichopeforsurgeonsintakingeverymeasureto achievedesiredresultsinonesurgery,reducingor eliminatingtheneedforanothersurgery,especiallyfor removingcancerouscells.

Oneofthemostconcerningissuesamongstwomen worldwideisBreastcancer.Inordertoremovethetumor cellscompletely,womenhavetogothroughvarious procedures,surgeriesandmultipleroundsoftreatment.As thenumberofre-excisionsurgeriesincreasesalongwiththe impairedtissue,thehealthytissuetoogetsaffected.

Thankfully,thereismedicalimagingtechnologytodaythat canhelpsurgeonseffectivelyvisualizesurgerymarginsin theoperatingtheatreitself,significantlyreducingthe excessivenumberofre-excisionsurgeries.Theleading manufacturerandproviderofthisground-breakingimaging technologyisKUBTechnologies,Inc.

BasedinStratford,Connecticut,KUBTECischallenging thestatusquoofbreastcancersurgeryandiscommittedto reducingtheexcessivenumberofre-excisionsurgeries. Leadingthecompanyinitsinnovationandgrowthisthe company'svisionaryFounderandCEO VikramButani.

In the following excerpts, we will get to know more about KUBTEC's journey in bringing empowering medical technology solutions to the market and their specialties.

ASuperiorandFasterSolution

WhenVikramfoundedKUBTECin2005,itwaswitha missiontoprovidebest-in-classspecimenimagingfor pathologybecausehefoundoutthatmostfacilitieswere usingoldX-rayfilm-basedequipmentorlow-resolution general-purposecabinetsystems;astheir“standardof care.”Hethoughttheremustbeabetterway,soheandhis teamdesignedasuperiorsolutionwithproprietaryfeatures thataddedvalueandreducedturnaroundtime,enabling themtoprovideresultsfaster.

“Today, KUBTEC is an acknowledged leader in the field of breast cancer margin management, and our systems can be found in pathology, radiology and ORs around the world. So, our affinity for the pathology imaging space runs through the entire fabric of Kubtec,”Vikramtoldus.

Today, KUBTEC is an acknowledged leader in the field of breast cancer margin management, and our systems can be found in pathology, radiology, and ORs around the world.

TheVisionaryLeader

VikramButani,theFounderandCEOofKUBTEC,comes fromafamilyofdoctors.Notpursuingacareerinmedicine, Vikramwaslookingforanopportunitythatcouldmakea differenceinhealthcare.Reminiscingabouttheinitialidea forthecompany,Vikramsays, “When I came across the need for superior imaging of excised tissue in pathology, I decided to pursue the challenge. My wife and I started the company out of our spare bedroom.”

Further,heemphasizesthat“Our commitment was and has always been to provide more personalized and attentive service and support to our customers and their patients.”

Vikramandhisteambuiltcustomerloyaltyfromasmall installbaseandthendevelopedaportfoliotoleveragethe company’stechnologicalsuperiorityintotheORand biopsysuites,whichwereandstillarethedomainsof radiology.“While doing our research, we learned breast cancer surgery has a very high re-excision rate. Studies show that close to 30% of patients need to come back for a second surgery as the surgeon was unable to clearly visualize their margins at the time of surgery, and it's not until they receive the final pathology report that they would know if the operation was a success.”

ThatconfirmedtoVikramandhisteamthattherewasa verycloserelationshipbetweenthebreastsurgeonsandthe pathologygrossroom,givingtheteamawholenew directiontoexplore.Thecompanysetouttosolvethis problemandlaunchedtheMOZARTSpecimen Tomosynthesis(3D)system,whichbringsanelementof real-timepathologyrightintotheOR,enablingsurgeons andradiologiststoaccuratelyidentifypositiveorclose marginsintraoperatively.“KUBTEC’s journey has been part evolution, part revolution, with everything based upon a constant stream of proprietary innovation created by the company,”Vikramadded.

OnaMission

Informingusmoreaboutthevisionandmissionstatement forthecompany,Vikramsays,“Well, within the digital pathology community, our mission is simple and practical. We’re on a mission to improve patient turnaround time in pathology.”

Pathologyprofessionalsplayanimportantroleinthe deliveryoftimelyandeffectivepatientcare,soKUBTEC

createsproprietaryproductsandservicesthatenablethem tobemoreefficientbyreducingspecimenhandlingtime. Withinawiderframework,thecompanyisfocusedon diseasestateswhereitstechnologycanmakeareal differenceinthedeliveryofcareforpatientsandproviders.

KUBTECisaprivatelyheldorganizationthatdoesnot answertoWallStreetoranonymousinstitutional shareholders.Vikramtellsus,“Whenever we see an opportunity to improve the delivery of care, we move quickly.”Infact,thecompany'smanifestostatesthat “Impatience is our virtue.”

ThegoalofKUBTEC'smanagementistoalwaysbefirstto marketwithnewinnovations.Assuch,itstrivestomakea life-changingdifferenceforbreastcancerpatientsand regardseverysurgeryasanopportunitytoimprove someone’slife.

Inaddition,thecompanyvaluessimply“doingtheright thing,”behavingethicallyandthoughtfully,being accountableand“creatingsocialchange.”Vikram underlinesthat“We champion our role as good corporate citizens and are driven to make a difference by supporting

Vikram Butani Founder and CEO

initiatives that reduce inequality and improve the health and well-being of those everywhere.”

WhereInnovationhasNoEnd

Whenaskedaboutwhatkeepsthecompanyapartfromthe competitorsintheindustry,Vikramrespondedwith, “Innovation, Innovation, Innovation.”

He adds, “Not just in product technology but also in the way we support our customers. We live in a totally connected world where customer expectations for support are more than just a 24-hour 1-800 number.”

Hecontinues,“From the very first system we installed in 2005, all KUBTEC systems feature remote support where we can troubleshoot any of our systems and automatically perform software updates right from our Technical Center.”

KUBTECXPERTandMOZARTsystemsfeature KUBALERT,whichconductson-boarddiagnosticsand sendsoutareporttopreemptasystemfailure.The companyrecentlyintroducedtheKUBTECApp,which willhelptheuserreachafactorysupportengineer instantaneouslythroughtheapptoeliminateanydowntime.

3DTomosynthesisTechnology

3Dtomosynthesistechnologyisoneofthemajorsolutions offeredbyKUBTEC.Revealingmoreaboutthistechnology solution,Vikramtellsus, "3D tomosynthesis, embodied in the KUBTEC MOZART system, enables surgeons to make better intraoperative decisions based upon an image that accurately reflects the true anatomy of the specimen."

Headds, “Clinical studies have shown that use of the MOZART system reduces re-excisions by 50%, preserves healthy tissue for better cosmesis, improves surgical efficiency and lowers costs. That’s good news for the patient, the hospital, and the payer.”

EmpoweringClinicianswithTechnology

OnlyKUBTECusestomosynthesistoprovideclinicians andpathologyprofessionalswiththree-dimensionalimages ofsurgicalspecimens.Thisenablesthemtoidentifythe exactlocationofthetumoranditsproximitytoalledgesof thespecimen.Ifadditionaltissueexcisionisrequired,they candoitrightthereaspartoftheindexprocedure.

What’smore,thedata-rich3Dimageenablestheuseof artificialintelligencetoautomaticallyflagwhenthebiopsy clipistooclosetotheedgeofthespecimen;aKUBTEC patentedtechnologythatthecompanyisfurtherdeveloping toidentifyotherfeatures.

ConstantlyImprovingtheCustomerExperience

KUBTEC’steamisstronglyfocusedonprovidingaquality customerexperienceallthetime.Itconstantlylooksto improvethecustomerexperiencebymakingtheprocess moreefficient.

Explainingwhathelpedthecompanygainsignificant leadershipinthemarket,Vikramsays,“We were the first to introduce a larger imaging area of 8“x8” in 2005 and 16“x16” in 2007, when all that was available was 4“x4” . ”

Moreover,KUBTECwasthefirstcompanytointegratean opticalcameraandintroduceitsproprietaryblender technologyandthefirsttoofferadensityprofilefeaturethat isusefulforthebonedecalcificationprocess.

PartneringwithEarly-adoptersandInnovators

Innovativetechnologysolutionsarerapidlybecomingan integralpartofeverysector.Givinghistakeontheimpact oftechnologyadaptationinthehealthcaresector,Vikram says, “In my experience, a lot of healthcare providers are cautious about adopting new technologies, mainly because of their facility’s documented protocols and strict regulatory requirements.”

However,Vikramadds,“Our job is to seek out innovators or 'early-adopters' of new digital technology solutions and partner with them to acquire detailed insights into their pain points and ever-evolving demands to ensure our systems consistently meet their requirements now and in the future.”

ThispartnershiphelpsKUBTECtoestablishearly technologyadoptionatCentersofExcellencearoundthe worldthatcaninfluencea“new”standardizationofcare.

OfferingValuableGuidance

Vikramhasbeeninthehealthcareindustryforyears, focusedoncreatingadvancedpathologysolutions.With him,thereisvastwisdominresearchinganddeveloping

medicaldevices.Fromhisexpertise,heoffersthenew aspirantsinthepathologyspacethefollowingwordsof guidance:

Hesays, “I am a great believer in being laser-focused on patient outcomes, and with that, you uncover customer pain points or their unmet needs. Technology has come so far, and there is a lot of room to make the pathology process more efficient and more effective.”

Demonstrating Excellence

"You have a much better view with specimen tomosynthesis of exactly what needs to be removed. I avoid excessive tissue being taken from the patient, and the patient likes it, because the cosmetic result is better."

"Specimen tomosynthesis is a nobrainer. If you're a breast surgeon and you want to provide the best care, this is it. To identify whether you've done the right operation, you need this."

Cary Kaufman, MD, FACS Associate Clinical Professor of Surgery, Bellingham Regional Breast Center

"For my practice, and many breast cancer centers of excellence around the world. Using 3D specimen tomosynthesis during surgery has helped the best surgeons reduce their re-excision rates even more."

Sheldon M. Feldman, MD, FACS Chief of Breast Surgery and Breast Surgical Oncology and Director of Breast Cancer Services at Montefiore

“Few people focus on pathology as it is not as glamorous as some of the other departments. If you have something that you believe can make a difference and help improve workflow, then speak to the pathologists, speak to the PAs, and speak to the laboratory professionals before you take off on a business venture,” marks Vikram.

TheWayOnwards

Expandingontheplansforthecompanyfortheremaining partof2022andonwards,Vikramsays,“We’ve just launched a new product, the GammaPRO system, which is a highly advanced Wireless Sentinel Lymph Node Localization Technology, and we have other new platforms in the pipeline for this year and next.”

TheofficesofKUBTECweremovedintotheircurrent buildingin2021,andalreadytheteamhasoutgrownit.The companyhasacquiredsomelandadjacenttoitsHQin Stratford,CT,andwillbebreakinggroundonanew manufacturingfacilitylaterthisyear.“Weareconstantly hiringforengineers,salesandmanufacturing,whichisa greatchallengetohaveintoday'seconomicenvironment,” Vikramstated.

Awards:

Marcum Tech Top 40: 2019, 2020, 2021

References:

Health

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Kornfeld H, Mulder L, Spivey T, Cortina C, Madrigrano A, Kopkash K. Breast J. 2019;25:766-768. 3. Park KU, Kuerer HM, Rauch GM, Leung JWT, Sahin AA, Wei W, Li Y, Black DM. Digital Breast

MD, FACS Chief of

Roshni Rao,

Breast Surgery Program at New York-Presbyterian/Columbia University Irving Medical Center

Tomosynthesis for Intraoperative Margin Assessment during BreastConserving Surgery. Ann Surg Oncol 2019:26:1720-28.