10 Best Companies in Nutraceutical Market 2023

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Medical Kiwi Transforming Healthcare with its Unique Seed-to-SaleApproach February Issue 07 2023 Nutraceutical Best Companies in 1 Market 2023 A Health Outlook How Can Nutraceuticals Improve the Quality of Living Emerging Ways Use of Nutraceuticals in Treatment and Prevention of Diseases Mosese Nasalo CEO Medical Kiwi

Good Nutrion can be the Savior of Your Life

Edit or’ s Note

Exploring the Booming Nutraceutical Industry: Trends, Challenges and Opportunies

Thenutraceuticalindustryisgrowingatan

unprecedentedrate,andit'snosurprisewhy.With morepeoplebecominghealth-consciousand lookingfornaturalwaystoimprovetheirwell-being,the demandfornutraceuticalproductsisontherise.Butwhat exactlyarenutraceuticals?

Nutraceuticalsareproductsthatarederivedfromfood sourcesandhavemedicinalorhealthbenefits.These productsincludedietarysupplements,functionalfoodsand beverages.Theyhavegainedpopularityduetotheirability toprovidehealthbenefitsbeyondbasicnutrition.

Oneofthemajortrendsinthenutraceuticalindustryisthe useofnaturalingredients.Consumersarebecomingmore awareoftheimpactthatsyntheticingredientscanhaveon theirhealth,andarelookingforproductsthatusenatural ingredientsinstead.Thishasledtothedevelopmentofnew productsthataremadefromnaturalsources,suchasplant extractsandbotanicals.

Anothertrendistheuseofpersonalizednutrition.With advancementsintechnology,it'snowpossibletoanalyzean individual'sDNAandcreatepersonalizednutritionplans basedontheirgeneticmakeup.Thishasopenedupawhole newmarketfornutraceuticalproductsthatcatertospecific geneticneeds.

However,thenutraceuticalindustryalsofaceschallenges. Oneofthebiggestchallengesisthelackofregulation.

Unlikepharmaceuticaldrugs,nutraceuticalproductsarenot subjecttothesamerigoroustestingandapprovalprocess. Thishasledtoconcernsaboutthesafetyandefficacyof theseproducts.

Anotherchallengeisthegrowingcompetitioninthe industry Withmorecompaniesenteringthemarket,it's becomingincreasinglydifficulttostandoutand differentiateproducts.Thishasledtoafocusoninnovation, withcompaniesinvestinginresearchanddevelopmentto createnewanduniqueproducts.

Despitethesechallenges,thenutraceuticalindustrypresents awealthofopportunitiesforcompaniesandconsumers alike.Asthedemandfornaturalandpersonalizedhealth productscontinuestogrow,thereisplentyofroomfor innovationandgrowthinthisexcitinganddynamic industry

InthelatesteditionofInsightscare,webringtoyour referencethe10BestCompaniesinNutraceutical Market2023thatarebringingthenaturaltouchtothe HealthcareIndustrywiththeirsafeanddurable neutraceuticalproducts.

Hope you have an insightful reading!

UseofNutraceuticalsin TreatmentandPrevention ofDiseases EmergingWays 36 HowCanNutraceuticals ImprovetheQualityofLiving AHealthOutlook 22 Aicl Aicl America Medic & Science CollaboratingNatureand TechnologyforaHealthierFuture 18 Anagenix InnovatingPathwaysfor NaturalHealthSupplements 26 Ingredia MakingHealthSustainable throughUniqueDairyBioactive Ingredients 32 Rebalance Health UsingtheScienceofCortisol RebalancetoOptimizeLife 40
C  t 
Medical Kiwi TransformingHealthcare withitsUniqueSeed-toSaleApproach 08 CovSty
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February, 2023

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are also available on :

Description Company Featuring Person

Alaron Products Limited alaron.co.nz

America Medic and Science americamedic.com

ANAGENIX anagenix.com

EuroPharma europharmausa.com

Ron Geiger MD

Alaron Products Limited specialise in custom manufacturing of dietary supplements, complementary medicines, therapeutic goods and personal care products

Moe Kaadan CEO

Chris Johnson Managing Director

Alex Fenech GM

America Medic & Science AMS is an American nutraceutical company headquartered in Seattle, Washington. It specializes in the manufacturing of natural products and dietary supplements.

Established in 2010, the Anagenix is a New Zealand nutraceutical companies that are responding innovatively to the global need for natural health solutions.

EuroPharma’s desire is to bring proven, high quality products to health food stores across America through its Terry Naturally® nutritional supplement line.

Ingredia ingredia.com

Keiser Tammy Director, Sales, Marketing

Kemin Europa kemin.com

Dr. Chris Nelson CEO

Ingredia is a major player in the global industry of dairy ingredients by developing and producing products emanating from milk cracking.

Kemin Europa is a global ingredient manufacturer that strives to sustainably transform the quality of life every day for 80 percent of the world with its products and services.

Medical Kiwi medicalkiwi.com

Origin Nutraceutical originnutra.com

Rebalance Health rebalancehealth.com

Mosese Nasalo CEO Medical Kiwi is a pioneering research & wellness company, creating & distributing medicinal and nutraceutical cannabis products.

Israel Haroldsen President

Justin Hai CEO and Co-founder

Rhema Health Products Limited rhemamade.com

James Pratt CEO

Origin Nutraceutical helps startups, medium, and large companies to manufacture their products. Also, it offers all the tools an entrepreneur needs to launch his/her brand.

Rebalance Health, Inc. is an optimal health and performance company reinventing how and why we take supplements, aka nutraceuticals.

As a custom manufacturer of tablets, capsules and flavoured powder drink mixes, Rhema Health Products Limited offers a first-rate quality experience and an innovative approach to its clients’ challenges.

10 Best
Companies in Nutraceutical Market 2023

Medical Kiwi

Medical Kiwi's operations will cover the full process from cultivation to the production of rapidly evolving consumer goods.

Transforming Healthcare with its Unique Seed-to-Sale Approach
C o v e r S t o r y
Mosese Nasalo CEO Medical Kiwi

Technologicalupgradeshavebecomeapartofdaily living,whichisrevolutionizingthewayindividuals experienceanyproduct.Butintheseadaptations, somearemissingthenaturaltouchintheservicesthey consume,especiallyinthehealthcaresector

Forsimilarreasons,peopleareseekingtreatmentsthatare organicandprovidealong-lastingcure.Onesuchcompany changingthewaytheworlddelivershealthoutcomesand incorporatingevidence-basednaturalnutraceuticalproducts isMedicalKiwi.

Thecompanyrealizestheneedsofconsumersandfocuses oncultivatingchangewithanewformulaforhealthand wellnessthatnotonlyblendsplant-basedcost-effective medicinewithsciencebutalsoinducesapositivedifference inpeople'shealthoutcomesandimprovetheirqualityof life.Ithasbackeditsservicesbasedontheresearchand experiencesofpeoplerelatedtocannabis,CBD,andother nutraceuticalproducts.Theyuseundiscoveredplantswith healingremediesthatforcenturieshavenotbeenseenby theWesternworldyethavebeencreatinganimpacton communities.

Leadingthistransformationofprovidingtheworldwith safeanddurablenutraceuticalproductsistheleaderand company'sCEO—MoseseNasalo,whoseexpertfinancial andmanagementskillsarehelpingMedicalKiwitobebest positionedinthemarketwhileassuringthebestproduct standards.Hebelievesthatmedicalcannabis,CBD,and othernutraceuticalproductsarepartofalongoverdue healthandwell-beingrevolutionthatreplacessomany otherpharmaceuticalsandwillbenefitmillionsofpeople. Givingshapetohisvision,heandMedicalKiwiare bringingtheseproductstomarketinNewZealand, Australia,andglobally

Let us read more about their promise of being organic in the nutraceutical industry!

TheFoundationalValuesofChange

Thejourneyofanestablishedcompanyinthecompetitive marketismadesmootherifitstandsbyitsinitialobjective ofservingthepeople.ForMedicalKiwi,thispurposehas beenbasedonhelpingpeopletoliveaquality,healthierand happierlife.

Elaboratingonthewhyofthesecorevalues,Mosesesays, “We've seen too many people suffering from chronic pain and other ailments that cannot be managed by existing

drugs and medicines. We've seen first-hand of people becoming a victim of health poverty, that is expensive medicine are restricting people of living quality of life and enhancing an unproductive society.”

Consideringthesechallenges,MedicalKiwi'smissionis aboutcultivatingchangewithanewformulaforhealthand wellnessthatblendsplant-basedcost-effectivemedicine

withsciencetomakeapositivedifferenceinpeople'shealth outcomesandimprovetheirqualityoflife.

Thischangeandadaptiontoplant-basedproductsare exacerbatedbytheirteamofprofessionalsinmedicine, biochemistry,governance,andsales,whoarecommittedto assuringseedtosale.Talkingmoreaboutthis,Mosesesays, “Medical Kiwi's operations will cover the full process from cultivation to the production of rapidly evolving consumer goods.”

GivingBackwithKeyOfferings

TheircoreproductismedicinalcannabisandCBD,which accordingtovariousresearchandpeerreviewjournals,is

10 Best Companies in Nutraceucal Market 2023
Our state-of-the-art facility is located in the South Island of New Zealand, and we have a team of experts working to grow and sell our medicinal cannabis internationally, at this stage this is a B2B proposition.

believedtoimproveatleast50conditions,includingpain, seizures,musclespasms,nauseaassociatedwith chemotherapy,digestivedisorderssuchascolitisand inflammatoryboweldisease(IBD),degenerative neurologicaldisorderssuchasdystonia,multiplesclerosis, Parkinson'sdisease,mooddisorders,anxiety,PTSD,and highbloodpressure.

Also,therearemanyproductsonthemarketatthemoment thatclaimtobesustainableandenvironmentallyfriendly whilstgivingbacktothecommunitiestheyarefounded upon.ThedifferencewithMedicalKiwinutraceutical productsisthattheyuseundiscoveredplantswithhealing remedies,thatforcenturieshavenotbeenseenbythe Westernworldyethavebeencreatinganimpactwithinthe MalaitanIslandercommunityintheSolomonIslands.

Mosesesays, “By creating a partnership with this community, we have been able to create an exciting range of products that will introduce the world to the undiscovered people and plants of Malaita. This introduction will set a new standard of healing, one which we have all been waiting for.”

Thecompanyisexpandingitscurrentprovisionsasits topicalproductlineisduetolaunchintheAustralianand NewZealandmarketsinthefirstquarterof2023,whichisa skincareproductusingMalaitanplants,tailoredforboth adultsandchildren.Mosesecomments, “This is just the start for Medical Kiwi.”

Aspartoftheirendeavorstointroducenewproductsinthe marketandensurecurrentofferingsareinlinewith evolvingresearch,theyareassistedbytheirteamof ScientistsattheUniversityofVictoriaofWellington,who arecontinuingtoresearchtheirpatentedbio-active compound,Balaenone,thatwillbeprogressedtoa biopharmaceutical.

Alongsideextensiveresearchandindustrycollaboration, MedicalKiwiseesitselfattheforefrontofprovidingpeople withbetterandmorenaturalhealthoutcomes,whilstgiving backtothosethroughwhichitwasfounded.Mosesesays, “Each of our future products, whether cosmetic, nutraceutical or biopharmaceutical, will reflect this.”

Theirseed-to-saleverticalintegrationapproachisexpected tosetthemapartfromothercompaniesinNewZealandthat mightfocussolelyoncultivationorresearch.

SeedtoSale–EnrichingHealth

Thecompany'smissionis'betterhealthoutcomes, naturally.'Theyareaverticallyintegratedmedicinal cannabiscompany,fromseedtosale.Talkingmoreabout this,Moseseexplains, “Our state-of-the-art facility is located in the South Island of New Zealand, and we have a team of experts working to grow and sell our medicinal cannabis internationally, at this stage this is a B2B proposition.”

We have worked

Thisefficientchainofoperationsanddistinctiveidentityof thecompanyinthemarketarepossibletodaybecauseofthe ablemanagementensuredbyitsleader

TheInspiringCEO'sTale

TheacademicjourneyforMoseseendedwithgraduation fromMasseyUniversity'sExecutiveMasterofBusiness Administration(EMBA)program.Toupskillandaddtohis knowledge,healsopursuedanAustralianInstituteof BusinessPost-GraduateDiplomainManagement(Finance) andanAustralianInstituteofBusinessPost-Graduate CertificateinManagement.

hard to develop extensive networks both nationally and internationally. We consistently talk to our partners and continually assess the industry.

Heheldarangeofmanagementandexecutiverolesin SumitomoCorporation,aJapan-basedconglomerate500 fortunecompany–workingindifferentregionsglobally, fromAsiatoMiddleEast&AfricatoNorthAmerica.He shares, “I started with Sumitomo as an operations manager in the group's beverage manufacturing facility in South Canterbury. My early career was also in this home locality, where I was a team leader with the food processing company McCain Foods New Zealand.”

HewasevenassociatedasaGlobalCommercialManager forWestlandMilk,responsibleforthedairycompany's commercialactivitiesinAustralasia,SoutheastAsia,Europe andtheMiddleEast.

Finally,intheprogressionofhisprofessionaljourney, MosesejoinedMedicalKiwiasChiefExecutiveinApril 2022,bringingverysolidexperienceinoperationaland financialmanagement,andsalesandmarketinginNew Zealandandinternationally

Heisinfusinghisacademicknowledgewithhis managementskillstoservetherequirementsofthecurrent andcomingdemographics,tokeepthewheelsoforganic healthcarerunning.

SupplyingfortheFuture

Thecompanypaysattentiontofulfillingtheneedsofthe currentandsubsequentgenerations.Itisawareofthetrend ofthenewgenerationwhichisembracingtheneedfor changethroughenvironmentalsustainability,socialimpact, andcleanerliving.

Mosesebelievesthattheeaseofaccesstomanyplatforms hasputforwardthequestionsofwhatanindividualis puttingintotheirbody,creatingthedesiretobecleaner throughmorenaturalproductsandfoods/resources.They feelmoreconfidentinadvocatingfortheirmedical treatment,notshyingawayfromintegrativehealthand complementarymedicines.

Includingthesesetoflifestyleapproachesintheirproduct delivery,theyaresettobeapartofthewaytheworld deliversitshealthcarewithaninnovative,science-based approachtodevelopinganddeliveringplantbasemedicinal productstothosewhoneedthemthemost.

Mosessays, “Our robust research, innovative product development, partnerships with global industry-leading companies, and agreements for future sales put us in a

unique position to create value and carve out a significant share of this emerging and exciting industry in New Zealand and globally.”

Despitetheirstrongdeterminationandfocus,theyarefaced withmultiplesituationsthattesttheircommitmentto innovatinghealthcaresolutions.

LearningWithChallenges

Thebiggestchallengetheleaderandtheteamhavelearned andcontinuetolearnaboutis–challengingtheperception

ofeverydaypeopleandhealthprofessionalsregardingthe useofmedicinalcannabisandpharmaceuticalalternatives.

SheddinglightonthewaysMedicalKiwistaffisadopting inbuddingthroughthesethorns,Mosessays, “Although they have been used for generations on an individual basis, we are still in their infancy in clinical trials and prescribing. It is a challenge that we are embracing as we see ourselves being major players and contributors to the revolution of health and well-being.”

We will continue to advocate, conduct research, and provide the necessary education to give people the opportunity to access better health outcomes, naturally.

Theseadaptationstofulfillcurrentindustrialdemandsare inspiringotheryoungmindstoservetheindustrybetter, oncetheystepfootinit.

AdvicetoGenerations

Aleader,whoisabreastwiththeneedsofthemarketalso comesasaguidinglighttoyoungmindswhoaspireto makeaprofessioninthefield.Beingsuchaleader,Mosese shareshiswordsofadviceforfutureentrants.

Hesays, “Understand your target market, and what you are trying to achieve and ensure you know the regulations and laws around bringing your products to market. Reach out to the experts in your industry who have walked this path before and immerse yourself in their knowledge.

Asafurthermodelforthemtofollow,hesharesthe practices,heandhisteamfollowtobuildthecompany's namefurther.Hefurtheradvises, “We have worked hard to develop extensive networks both nationally and internationally. We consistently talk to our partners and continually assess the industry.”

UpscalingtheWork

Asapartofitsfuturegoalstopenetratedeeperintothe market,thecompanyiscontinuingtoworkonitsbotanical productrangewhoselaunchisscheduledfor2023.Theyare evenexpandingtheirtelehealthandbrick-and-mortarpain clinicsintoAustralia.

Mosesestates, “We will continue to advocate, conduct research, and provide the necessary education to give people the opportunity to access better health outcomes, naturally.”

FigurineofPraises

Thecompany,beingthebestinthenutraceuticalmarket, hasbaggedprestigiousawardsforitscontinuous contributiontotheindustry.TheyhavewontheGlobal HealthandPharmaceutical(GHP)awardandhavebeen renownedastheMostInnovativeEmergingMedical CannabisCompany2022–Australasia,certifyingtheir credenceintheconcernedsector

Our robust research, innovative product development, partnerships with global industry-leading companies, and agreements for future sales put us in a unique position to create value and carve out a significant share of this emerging and exciting industry in New Zealand and globally.
February 2023 18|www.insightscare.com
Moe Kaadan CEO America Medic & Science

Collaborating Nature and Technology for a Healthier Future

Bioaccumulationhasbecomeacauseofconcernfor

humanwell-beingformanyenvironmentalists, otheracademicians,andmedicalpersonnelinthe st21 century.Butwhatbreaksthischainisacognizantturn towardsorganicfarming.

Asimportantandtrendingasorganicfarmingis,itisalso noticedthatforanindividualtogetallthenutritional elements,therehastobeamediumtocombinethebenefits oforganicfarminganddeliveritsafelytoeachandevery household.

AmericaMedic&Sciencerealizedthisneedandis delivering100percentsafe,naturalandGMP-approved productstoitscustomersforthelastthreedecades.Itis highlycommittedtoempoweringindividualsofallages, helpingthemleadhealthylives,andbuildingbrighter futuresbyprovidingthemwiththehighestquality nutritionalsupplements.Withitsinnovativeteamandstateof-artmanufacturingunitthatisFDA-approved,itis cateringtodiversemarketcohorts–fromfemale&male supplements,andchildren’shealth,toweight-control products–thatareinfusedwithessentialvitaminsand minerals.

ThistransformationinthenutraceuticalmarketbyAMSis possiblebyitsCEO–MoeKaadan,whoisnotjusta committedleaderbutamulti-talentedathlete,traveler, explorer,andmuchmore.HebeganAMSwithasmallidea thathasnowtransitionedintoateamofover100 employees,sendingoutthousandsofproductstosomeof thebiggestcountriesintheworld!

AMS is always about seeking and helping to transform the future into a healthier, and more wholesome one, let us see how by delving into the story below!

AMSInception–ADreamComeTrue

AMS’journeybeganinJanuary2007,asaresultofthe CEO’spassionforentrepreneurship.Moeexpresses, “It wasn’t easy back then, as I sustained my job while brainstorming strategies to fuel this young idea. But once it showed signs of growth and progress, I quit my job to realize its fullest potential.”

AMSistheproductofhis15-yearexperienceasaMobility andCivilEngineerininternationalfirms,withnowthree decadesofpharmaceuticalexpertisewiththebrilliantteam ofAMSthatitbringstotheworld.Whatbeganjustasan ideaforconventionalpharmaceuticals,isnowaglobal nutraceuticalfirm.

Today,AMS’cutting-edgetechnologyhasreachedallmajor continents.Moeinformsthattheyhavepartneredwithtop globalfigurestofosterinnovationanddeliverhigh-quality productstotheirconsumers.Butthebackbonetotheir successtodayistheirexperiencedanddedicatedteam whichhascreatedinnovativeproductsforthemarket.He highlights, “One of our biggest achievements is our expansion into natural fertility products which has yielded excellent results. On a regular basis, our team of over 100 employees sends out thousands of products to some of the biggest countries in the world. The foundation of such success is our company ethos. We believe in the progress of

10 Best Companies in Nutraceucal Market 2023
February 2023 19|www.insightscare.com
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It gives me immense pleasure to welcome you into our world of science, innovation and health. I encourage you to make us a part of your lifestyle and let us help you work towards a better quality of life.

our employees and executives, and the adherence to social values and sustainability.”

DistinguishedProductOfferingsforAll

AMSspecializesinthemanufacturingofnaturalproducts anddietarysupplements.Theypreciselycatertothemarket thatprovidesmale&femaleFertilitysupplements,Weight Control,Cardiovascularhealth,Energy,MentalFocus& Health,Children’sHealthandEssentialVitamins& Minerals.Afewoftheirpopularproductsinclude:

Ÿ Florabiotixtakesanaturalapproachtoguthealthwith 10probioticstrainsand30billionlivecultures.

Ÿ ImmunexabyAMSisa7in1immunityboosting supplement

Ÿ AMS®PearlyCapsisadietarysupplementthat improvestheappearanceofyourskinbyactingon brighteningandunifyingtheskintone.Also,itworks onclarifyingtheskinfromanyimpurities.

Ÿ AMS®Ova-Maxisanaturalblendofvitamins, mineralsandantioxidantswhichworktogetherto improvewomen’seggandembryoqualityby strengtheningtheantioxidantdefensemechanismthus preventingoxidativestress.

Theyalsohavesupplementscuratedsafelyforchildrenthat boosttheirhealthandnutritionstartingfromyoungeryears. Theseareintheformofnaturallyflavoredliquidated formulasofdietarysupplementsthatcoverchildren’sdaily needsofvitaminsandmineralswhichareessentialfortheir growingyears,healthyphysicalandcognitivedevelopment, andoverallwellness.Someoftheseinclude:

Ÿ PediaWellBasic

o Providesthreeessentialvitamins–vitaminA,C andD3

o HasFluoridetosupporttoothbuildingyears

o FreeofParabens,completelynaturalwithexciting flavors

Ÿ PediaWellD-400

Ÿ PediaWellIron,etc.

Whatsetsthemapartfromothersinthemarketisthattheir rangeofproductsincludes100percentnaturalsupplements andproducts.Moeinforms,“All our products are GMP approved and are manufactured in our state-of-the-art FDA Inspected and Registered Facilities. We are also members of the Natural Products Association. ”

Withitshealthyandnaturalproductofferings,AMSis highlycommittedtoempoweringindividualsofallages,to helpthemleadhealthylivesandtohelpthembuildbrighter futuresbyprovidingthemwiththehighestqualityof nutritionalsupplements.

Sinceitsinceptiontilltoday,AmericaMedic&Sciencehas emergedasaleaderinitsindustryundertheleadershipof itsmanagementteam.

AHealthifyingVision

Behindthecompany’ssuccessisthelong–termvisionofits CEO–MoeKaadanwho,withhisteam,isstrivinghardto makeAMSthetrustedgloballeaderinthefieldof nutraceuticals.Hesays,“This vision drives and motivates me to get up and go to work every day. I take pride in extending our hand to individuals of all ages with health concerns that can be addressed with quality, safe and organic nutritional supplements to complement a variety of lifestyles and diets. I believe that together we can build a brighter and healthier future.”

MoestartedwithhiscareerwhenhemovedfromLebanon totheUnitedStatesinpursuitofhighereducation.From therehebeganonhisprofessionaljourneywithhisfirstjob asaMobilityEngineerfor10yearsandthenasaCivil Engineerfor5yearsinwell-renownedinternationalfirms.

BeingtheCEOofAMS,hesaysthathecanpersonally assureforAMSsupplementsashehimselfisacustomer too.Hesays,“It gives me immense pleasure to welcome you into our world of science, innovation and health. I encourage you to make us a part of your lifestyle and let us help you work towards a better quality of life.”

AspiringForaBetterFuture

LifeatAMSisalwaysaboutseekingandhelpingto transformthefutureintoahealthier,andamorewholesome one.Throughinnovation,diligentresearchandresolute commitmenttoitsconsumers,AMShopestobringthe bountyofnatureintoeveryhomeandreintroduceitasa dailypracticeinitscustomers’busy,fast-pacedlives.

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Nutraceuticals How Can Improve the Quality of Living

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Inrecentyears,anewparadigmofhealth-related nutritionappears,emphasizingthepositiveaspectsof nutrition.Today,thenewlifestyleadoptedbypeople haschangedthebasiceatinghabitsofthelatter.The consumptionofjunkhasproliferated,leadingtomany diseasescausedbyimproperdiet.

Obesityisnowrecognizedasaglobalproblem.Heart diseaseremainstheleadingcauseofdeathinmost developingcountriesworldwide,followedbycancer, osteoporosis,arthritisandmanyothers.Consumers disillusionedwiththeexpensivehigh-techailmentsof modernmedicinearelookingforcomplementaryor alternativebeneficialproducts,andthebureaucracyof managedcaremakessupplementsespeciallyattractive."Let foodbethymedicine,andmedicinebethyfood,"quotedby

A Health Outlook February 2023 23|www.insightscare.com

Hippocratessome2500yearsago,iscertainlyaprinciple today

Nutraceuticalsareanemergingclassofnaturalproducts thatblurthelinebetweenfoodandmedicine.Althoughthe useofnutrientshasalonghistory,onlyrecently scientificallysupportednutritionalandmedicalevidence hasallowednutrientstobeeffective.

Let's dive in to learn about how Nutraceuticals can improve the quality of living:

Nutrientsarefoundinmosaicproductsfrom(a)thefood industry,(b)theherbalanddietarysupplementmarket,(c) thepharmaceuticalindustry,and(d)recentlymerged pharmaceutical/agricultural/nutritionconglomerates.This canrangefromisolatedfoods,herbalproducts,nutritional supplementsanddietstogeneticallymodifiedso-called designerfoodsandprocessedproductssuchascereals, soupsanddrinks.

Nutraceuticalscovermosttreatmentareas,including arthritis,coldandcough,sleepdisorders,digestionand preventionofsomecancers,osteoporosis,bloodpressure, cholesterolcontrol,painrelief,depressionanddiabetes.

DietaryFibres

Solublecomponentsofdietaryfiberslowgastricemptying duetotheirbulkingandviscosifyingproperties.Itaffects thespeedofdigestionandabsorptionofnutrientsand createsafeelingofsatiety.Theyalsoimprovethebinding oftheinsulinreceptorandimproveglycemicresponse.In thecolon,fiberincreasesstoolvolumeduetoincreased waterretention,increasedtransittime,andincreasedfecal bacterialmassduetothefermentationofsolublefiber

Fiberalsopromotesthegrowthofbifidobacteria(especially fructo-oligosaccharides)inthegut.Peoplewhoconsume highamountsoffiberhavealowCHR,riskofstroke, hypertension,diabetes,obesityandcertaingastrointestinal disorders.Again,increasingfiber-richfoodimprovesserum lipoproteinlevels,lowersbloodpressureandimproves bloodsugarcontrolindiabetes.

Probiotics

Probioticsareavailableinvariousformssuchaspowder, liquid,gel,orpasteorgranules,capsules,etc.Specific probioticsarecommonlyusedtotreatgastrointestinal(GI) disorderssuchaslactoseintolerance,acutediarrhea,and antibiotic-relatedgastrointestinalsideeffects.Probiotics havenon-pathogenic,non-toxic,acid-fastpropertiesthat attachtointestinalepithelialtissuethatproduces antibacterialsubstances.Thereisevidencethattaking

probioticsreducestheriskofsystemicdiseasessuchas allergies,asthma,cancerandseveralotherinfectionsofthe earandurinarytract.

Prebiotics

Prebioticsarefoodingredientsthathaveabeneficialeffect onthehostbyselectivelychangingthecompositionor metabolismoftheintestinalmicrobiota.Healthbenefitsof prebioticsincludeimprovedlactosetolerance,anti-tumor properties,neutralizationoftoxinsandstimulationofthe intestinalimmunesystem,andreductionofconstipation, bloodlipidsandbloodcholesterollevels.

AntioxidantVitamins

VitaminssuchasvitaminC,vitaminEandcarotenoidsare collectivelyknownasantioxidantvitamins.Thesevitamins actbothindividuallyandsynergisticallytoprevent oxidativereactionsthatleadtoseveraldegenerative diseasessuchascancer,cardiovasculardisease,cataracts, etc.Thesevitaminsareabundantinmanyfruitsand vegetablesandworkthroughfreeradicalscavenging mechanisms.VitaminE,composedoftocopherolswith tocotrienols,transfershydrogenatomsandscavenges singletoxygenandotherreactivespecies,protectingPUFA peroxidationinbiologicalmembranesandLDL.

WrappingUp

Duetopeople'sever-changinglifestyles,antioxidant defensesystemsareoftenoverwhelmed,leadingto oxidativestress.Inaddition,theleveloftheantioxidant defensemechanismdecreasessignificantlywithage.They cancausethedevelopmentofmanydiseases.Thatiswhy researchhasfocusedmainlyondifferentnutrientsinrecent decades.Antioxidantproductscanworknaturallyby removingfreeradicals(egvitamins,PUFA)orspecifically stimulatingthebody'sdefensesystem.Thisreviewreflects thepotentialbenefitsandharmsofnutrientsinhealthy individuals.

However,aperson'ssusceptibilitytoacertaindisease dependsmainlyongeneticpredispositionandlifestyle disorderssuchassmokingandheavyalcoholconsumption. Thus,theresponsetofoodscanvaryfrompersontoperson. Nutrientshaveprovenhealthbenefitsandtheiruse(within reasonabledietaryrecommendations)keepsdiseaseatbay andallowspeopletomaintainoverallgoodhealth.

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ANAGENIX

Innovating Pathways for Natural Health Supplements

Naturaltherapyisturningintoamagicpillformost

peopleindulginginit.Thetimelinetoexperience thisisthoughconstrainedbecauseoflimitedspace, time,availabilityandavenues.Intheefforttoletitsbenefits lingeranddeliverthebestoforganicelementsfromnature toitsconsumers,leaders,throughtheirworkestablishments andresearchhavedevelopedproductsthatderivethe essenceofnatureandgifthumansahealthylife.

OnesuchcompanyisANAGENIX,whomanufactures naturalhealthandwellnessproductsandisbroadlybased onthreefoundationalpillars–Science,Marketingand SalesToolkit.

Theydeepdiveintothescienceofeachofingredients, identifyingpathwaysanddeliveringonefficacy.Thesecond pillarismarketing,wherethestrategicthrustisona bottom-upmarketingstrategy,startingwithendconsumers. Thethirdpillaristheirsalestoolkit,whichhasasuiteof technicalandmarketingmaterialstomakeiteasyfor distributorstoselltobrands,makingiteasyforbrandsto sayayes.

Thesethreefoundationalpillarsaresupportedbyconstant effortsbythethreehumanbrains–itsManagingDirector –ChrisJohnson,MarketingHead–ElizabethTay,and itsChiefScienceOfficer–DougRosendale.

Through the interview highlights below, let us know more about how the company and its products are delivering chemical-free health.

KindlybriefusaboutANAGENIXandthe developmentsorideasthatledtoitsinception

Anagenixisanaward-winning,leadingglobalmanufacturer andsupplierofinnovativenaturalhealthandwellness

ingredients.Wedelivercutting-edgesolutionsthatare backedby(clinical)science.Ouringredientsaremadein NewZealand,one-hundredpercentnatural,plant-based productswithaproventrackrecordincommercializing scienceintheglobalmarketplace.

Whatarethecorevaluesofthecompany?Howareyou drivingthecompanytoachieveitsmissionandvision statement?

InnovationisourDNA.Wehaveaninnovation-friendly culturethatencouragestheteamtothinkdifferentlyabout problems.Weworkcollaborativelywithpartnerssuchas growersandNewZealandCrownResearchInstitutesto bringtogetherthebestofknow-howandskills.Thisallows ustobringsuperiordifferentiatedofferingsandgive customersmarketadvantage.

Weareascience-orientedcompanyandeveryingredientwe bringtomarketisscientificallyprovenwithinvitro,invivo andclinicalstudies.Customersincludeouringredientsinto theirformulationwithfullconfidenceinhealthdeliverables.

Customershaveaccesstoourtechnicalandsalestoolkit, containingasuiteofcontentfromqualitydocumentsto whitepaperstomarketingfactsheetsandvideos.Weexpand thedepthandwidthofcontentinourtoolkitsonadaily basistoarticulatemarketopportunity,establishscientific evidence,developcommunicationandadoptionofour ingredients.

WhatarethekeyproductsandofferingsofANAGENIX andhowisitimpactingthedemographicconcerned?

Anagenix'sproductportfolioincludeActazin®,ourgreen kiwifruitpowder,andLivaux®,ourpatentedgold kiwifruitspowder,whichareclinicallyproventopromote

10 Best Companies in Nutraceucal Market 2023 February 2023 26|www.insightscare.com
Chris Johnson Managing Director Anagenix Ltd

The Three Brains of ANAGENIX

Chris was the first investor in Anagenix and ended up having to run it as the Managing Director. Since becoming MD, Chris has turned the company around. The business has seen exponenal growth under his leadership and won mulple accolades in the industry. Anagenix is held in high regard for its innovaon, agility and credibility, all these being values Chris has integrated into Anagenix's culture.

bowelregularityandmicrobiomebalance. Digestivehealthisatop5concernamongsupplement users.BothActazin®andLivaux®provideanaturaland effectivewaytosupportregularbowelandpromotea balancedgutmicrobiome.

Elizabeth leads the Markeng department of Anagenix. The focus on boom-up as opposed to top-down markeng has transformed our markeng approach from distributor/ customer to consumer-driven. Consumer insights including keyword research, SEO, blogs and social media are integral to our brand-building strategy.

BerriQi®,madefromBoysenberryandapple,isapatented ingredientandpromoteslungimmunitybalance,reducing post-infectionsymptomssuchascough,phlegmand wheezing.Asanaturallunghealthproduct,italsosupports otherimmunityrelatedconditionssuchas-asthmaand lungscompromisedfromsmokingandpollutionexposure.

Feiolix®ourmetabolichealthsupportingredient,is patentedtoimprovemetabolichealthsymptomsincluding bloodglucose,HbA1c,cholesterol,triglyceridesandweight gain.Itiswellsuitedforpeoplesufferingfrommetabolic dysfunctiontypicallyfoundinage40+population, includingmenopausalwomen.

Doug is a heavy-weight in the scienfic world. He holds a PhD in Engineering and Technology from Massey University and a Master of Science degree in Biological Sciences from The University of Auckland. Doug has the ability to deep dive into the science of an ingredient and structure it for commercialisaon.

AsAnagenix'singredientsaremadefromwholefruitswith alongsafehistoryofhumanconsumption,theyarewell suitedforthegeneralpopulationatlarge,including children,elderlyandpregnantwomen.

Howareyouusingemergingtechnologicalsolutionsto youradvantageandensuringsafeprocessesand products?Howisitrevolutionizingtheindustryyouare serving?

TheAnagenixTeamstartswithevaluatingthehealthtrends thatconsumersaremostconcernedaboutandseeking naturalsolutions.Oncethesetrendsorissuesareidentified

Chris Johnson Elizabeth Tay Doug Rosendale
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We deliver cutting-edge solutions that are backed by (clinical) science. Our ingredients are made in New Zealand, one-hundred percent natural, plant-based products with a proven track record in commercializing science in the global marketplace.

weapplythemostup-to-datesciencetechnologiesto explorenaturalproductstoaddressthesetrends.Welookat wholefruitandpartnerwithresearchorganizationsto evaluatethebio-activesinthem,usingthelatestanalytical chemistrytechniquestoseewhethertherearepossible solutionsfromthoseproducts.Wethenstartinvitro,invivo andfinallyclinicaltrialsusingthelatestbiomedical researchtechniquestoprovetheefficacyofournatural fruit-basedsolution.

Werevolutionizetheindustrybyprovidingpharma-quality evidencetosupportournaturalfoodproductsandshowthat theyreallywork,withdosages,stabilitydataand mechanismsofaction.WhileAnagenixisaB2Bprovider ofingredientswefocusontheconsumerwhowillbethe eventualpurchaserofourproducts.

Wearetappingintotoday'sdigitalconnectednesswithuser testingplatforms,andmarketresearchwithreal-time internationalpurchasingdatatorefineourawarenessof consumertrends,consumerpurchasingandproduct positioning.

Whatarethekeychallengesintheindustry?Howare youasaleaderturningthemintoopportunitiesto upscalethegrowthofyourorganization?

Findingsolutionsfortheconsumerthatarebackedby approvedclaims.Theregulatoryenvironmentaroundthe worldisgettingmorechallenging.Theconsumerwantsto knowataglancewhattheproductwilldoforthem;to legallyprovidetheseclaimsweneedtodevelopaportfolio ofsciencethatsupportstheclaimsandisapprovedbythe variousinternationalregulatorybodies.

Asanexperiencedleader,whatwouldbeyourwordsof advicetobuddingentrepreneurswishingtoenterthis industry?

Passion,resilience,hardworkandnevergivingup.

Itisalsoveryimportanttokeepyourcustomerinformedof yourproductdevelopmentprocesstomakesurethatwhat youaredevelopingwillmeettheconsumer'sneeds.So manyentrepreneurswanttheirproducttobeperfectbefore theygotomarket,thisnormallyendsinnotmeetingthe consumers'needs.Continualevaluationwiththecustomer throughthedevelopmentprocessensuresyouhitthemark withthefinalproduct.

Aboveall,themostimportantoftheseistohavepassion arounddeliveringhealthoutcomefortheconsumer

Whatareyourfuturegoalsforthecompany?Howdo youenvisionupscalingitsoperationsandreachin2022 andbeyond?

ANAGENIXstartedexportingtotheUSandhasdonevery wellinthismarket.WearenowconcentratingonEurope andthatisstartingtogrow,withlargebrandstakingupour ingredientstoformulateintotheirproductranges.

Wehaveanaggressivefive-yearroadmapwhichwill ensureANAGENIXisanimportantpartoftheglobal nutraceuticalandfunctionalfoodsupplychain.

Kindlyshareanyclientele,awards,orpublications.

Livaux®– wasawardedthePrebioticoftheYearbythe world'sleadingsupplements,healthandnutrition publicationNutraIngredients.cominitsUnitedStates, European,Asianawardcategories

Otherawardsinclude:

ŸLivaux®winsNutraIngredientsPrebioticoftheYearUSA 2022

ŸLivaux®winsNutraIngredientsPrebioticoftheYear Europe2022

ŸLivaux®winsNutraIngredientsPrebioticoftheYearAsia 2022

February 2023 29|www.insightscare.com
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Ingredia

Making Health Sustainable through Unique Dairy Bioactive Ingredients

Peopleingeneralhavegrownconsciousofmaking

healthierdietchoices.Today,theydisplayastronger preferencetowardsdietarychanges.Forinstance, theResearchDepartmentsuggeststhat64%ofconsumers intheU.S.arepersonallyconsciouswhenshoppinginthe food,beverageandsupplementmarkets.

Marketretailersunderstandthathealthyfoodchoicesgo beyondsimplyremovingsugarandsalt.It'smoreabout deliveringacompletenutritionalprofilewithanelementof deliciousness.Apartofitistheconsumptionofdairy productssuchasyoghurtandmilk.

Withitslow-fat,no-fatandfull-creamnutritionalvalues, dairyproductshavebecomeahealthieralternativeinthe foodindustry.Understandingitsactiveconsumptionrolein diets,IngrediaInc,atopsupplierofqualitydairy ingredientsisdedicatedtoservingtheindustrywiththe better-quality,nutritionalingredientsinsatisfyingitsmarket demands.TheUSsubsidiary,ledbyKeiserTammy,the Director,alsoplayingaroleinSalesandMarketing, partnersitsexpertswithcompaniesacrossNorthAmericato focusondietarysupplementsforhumanandpethealth, eachofwhichisfullofvaluableproteinsandbioactive ingredientsforensuredwellbeing.

Let's dive in to Ingredia's operations behind encouraging healthy lifestyles across the globe.

JourneySoFar

ItallstartedinthenorthofFrancein1949withthecreation ofafarmcooperative,ProspéritéFermière,whichwas

originallyamilk,creamandbutterbusiness.Inthe1980s, feelingmilkingredientscouldbettervalorizeitsfarmers' work,thecooperativecreatedaningredientdivisionnamed Ingredia,whichfirstsoldmilkpowdersandproteinstothe foodandnutritionindustries.Inthe1990s,itexploreda partnershipwiththeresearchersofNancyUniversity (France),andfinallyjumpedintothebioactiveingredients marketin2000,withthelaunchofLactium®,itsfirst unique,patented,clinicallyproveningredientforstress relief.Inthe2010sthreeotherlaunchesfollowedwith Prodiet®Colostrum(2002),Osteum™CPP(2013)and Prodiet®Lactoferrin(2015).Itisalsointhe2010swhen Ingrediagrewinternationally,withIngrediaIncbeing createdin2009,shortlyafteritsAsianaffiliate.In2019,the th companycelebratedits70 anniversaryin2019withthe th launchof5 bioactiveingredient,Pep2Dia®,apatented ingredientforhealthybloodsugarlevels.

KeyProductsandServices

Ingrediaisrenownedfortherigorousscientificbackground ofitsuniqueingredients.Forinstance,Lactium®is supportedby9clinicalstudiesinstressreliefandsleep improvementonmorethan500volunteers,butalsobya consumerstudyon300volunteers,statingeightoutoften arehappywiththeefficacy.

Ingredia'steamworksonbringingaddedvaluetoits customersthroughpatentsorbynegotiatingfunctional claimsallovertheworld.Service-wise,thecompany providesmarketing,regulatoryandapplicationsupport.For instance,marketingtoolsareprovidedforprescribers' convictions,oraB2B2Cwebsiteforconsumerreassurance.

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We aim to maintain our leadership in unique dairy bioactive ingredients. Ingredia, with a background for scientific and unique ingredients, reassures its customers in improving their health and life with proteins and bioactive. Ingredients.

KEISERTammy Director,Salesand Marketing Ingredia
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Tammybelievesthatco-brandingmustprovideadditional trustinthefinishedproductandworkonconsumercontent.

Inaddition,Ingredia'sR&Dteamalsospendsanaverageof 30%oftheirtimeoncustomersupport.

OperatingonSixCoreValues

Tammy,alongwiththeteam,seethemselvesasdairy explorerssince1949.Togethertheyrelyonsixcorevalues: Entrepreneurship,Innovation,Expertise,Performance, TeamSpirit,andCSR

AtIngredia,forinstance,10%ofitsstaffworkson innovationanddeliverstwotosixscientificpublicationsor clinicalstudiesperyear

CSRwise,itsplanthasreceivedadoubleCSRlabel."We investinbiomassenergyandtarget70%ofrenewable energyby2030toobtaintheISO50001norm.Weworkon theSustainableDevelopmentGoalsoftheUnitedNations. Wealsoaimatparity,withacurrent93/100women-to-men ratio,"emphasizesTammy

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With regards to some of its customers, who by themselves are deeply rooted in sustainable development and committed to their own community's welfare, it is a shared value that bonds Ingredia together with them. For this reason, it challenges us to constantly explore where's the next added value, be it through the highest standards of quality, clinical proof, innovation, or services.

ThemanifestothatTammyandherteamwanttosee embodiedis:"Becausewerespecthumans,animalsand nature;becausewebelieveininnovationrespectfulof traditionandtheland;andbecauseweloveourregionand itsauthenticity,wesupplymilkandmilkingredientsfora prosperousfuture,servinghealthandnutrition,respectfulof theplanet."Thecompanyaimstoachieveitineverything thatitundertakes.

EnsuringtheNextAddedValueforFarmersand Customers

Tomakesurecooperativefarmershaveaprofitableactivity andthatfuturegenerationswillstillenvisionafarmer's careerisIngredia'sbiggestresponsibility.

InsomecountrieswhereIngrediasellsbottledmilk,itcan goasfarasidentifying–throughblockchaintechnology–thefarmerwhoproducedthemilkthatconsumersdrink. That'sbusinesswithaface.

Withregardstosomeofitscustomers,whobythemselves aredeeplyrootedinsustainabledevelopmentand committedtotheirowncommunity'swelfare,itisashared valuethatbondsIngrediatogetherwiththem.Forthis reason,"Itchallengesustoconstantlyexplorewhere'sthe nextaddedvalue,beitthroughthehigheststandardsof quality,clinicalproof,innovation,orservices,"adds Michael.

SharingWordsofWisdom

Tammysharesherpieceofadviceforthebudding entrepreneurswhodesiretoventureintothedairyproducts industry. Shesays,"Weareconstantlyimproving,

professionallyandpersonally.Knowyourproduct(s)and howtheyareneededbyyourconsumers.Whetheryour productisforB2B,B2C,orB2B2C,asentrepreneursin anyindustry,wemusttakethetimetodevelopourteamand productstosucceed."

Havingasuccessfulteamisalsoessentialwhenitcomesto upholdingabusiness.Itwouldmeanhelping,mentoring andgrowingtogether.Hence,Tammyadds,"Surround yourselfwiththerightpeople,stayfocusedandpositive! Buildyourteamwithrespectandknowledge.Takenotice ofeachperson'sambitionsandgoalsandhelpcoachand guidethemtoachievetheirambitionsandgoals. Continuousimprovementinourselves,ourteams,andour productsisnecessaryforcontinuedsuccess."

UpscalingIngredia'sOperations

Thecompanyaimstomaintainitsleadershipinunique dairybioactiveingredients.Itenvisionsitsgrowththrough portfolioextensionwithnewtherapeuticareastocome,and reinforcingcurrentingredientswithadditionalclinical studies,additionalapplicationareas,andnewclaimsforonpackuse.

RecognizingAchievement

Tammyandherteamareproudtobetrustedby—Sanofi Aventis,DouglasLaboratories,LifeExtension,Swanson,or Metagenics,thecompanieswhosupportnaturalmedicine. ThisistheresultofIngredia'slongconvictionprocess basedonitsworkinclinicalproof.

Thisyear,inadditiontotheconsumersatisfactionstudy abovequoted,Ingredia'steamsawtheirstudyon Lactium®'smodeofactionbyBenoitetal.publishedinthe reviewNutrients."Wehopetocarryonbringing reassurancetocustomers,prescribers,andconsumersinthe comingyears,aswellasopeningnewfieldsforinnovation, withthefullpotentialofmilkingredientsthatarestilltobe explored,"concludesTammy.

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in Treatment Diseases

Nutraceuticalsarecharacterizedas"specially

formulatedpreparations"designedtomeetspecific nutritionalrequirementsand/orprovidepreventive healthcare.Nutraceuticalsarefood/nutrientcompounds thathelppreventandtreatcertaindiseasesinadditionto dietarysupplements.

NutraceuticalisatermcoinedbyDr.StephenDeFelicein 1989,derivedfromthetwowords"nutrition"and "medicine".Thesearefoodsorpartsoffoodsthatserveto providevarioushealthbenefits,includingtreatmentand/or

preventionofdisease.Thescienceofnutritionhasreached ever-newhorizons, frompredictingnutritionaldeficiencies tohumanhealthandthepreventionandtreatmentof chronicdiseases.Theterms"food",and"foodsupplement" haveevolved.

Nutrientsareusefulinmanytherapeuticareas,including coughandcold,arthritis,digestion,sleepdisordersand anti-cancer,depression,diabetes,cholesterol,blood pressure,andanalgesics.Nutraceuticalresearchand developmentsectorsareworkingattheirpeaktofindout

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howdifferentnutrientscanbeimportantinthe pharmaceuticalindustry.Thescientificneedsoffoods requirethestandardizationofingredientsandthecareful developmentofprotocols,aswellastheconductofclinical trialsthatsupportthehealthofconsumersandtheimpact onnutritioncompanies.

Let's dive into the use of nutraceuticals in the treatment and prevention of diseases:

NutraceuticalsinCardiovascularDiseases

Amongallotherdiseases,cardiovasculardiseasesshow importantriskfactorsthatacceptnutritionaltherapy There issubstantialevidencethatnutrientscanbeusedin cardiovasculardisease.

Cardiovasculardiseases(CVD)mainlyaffectbloodvessels andheartfunction.Cardiovasculardiseasesareoneofthe leadingcausesofdeath,accountingforapproximately30% ofdeathsworldwideeachyear.Dietarysupplementsare usefulintheriskmanagementandpreventionof cardiovasculardiseaseandcanbebroadlyclassifiedas thoseusedinthetreatmentofarrhythmias,congestiveheart failure,anginapectoris,hypertension,andhyperlipidemias.

NutraceuticalsinCancerChemoandRadiotherapy

Radiotherapyandchemotherapyaretraditionalanticancer treatments,buttheyhaveserioussideeffectsandvarious complications(e.g.pain,fatigue,diarrhea,vomiting,nausea andhairloss).Someformsofcancerarehighlyresistantto chemotherapyandradiotherapy,andthereforesystemic cytotoxicchemotherapyandradiotherapyarenotvery effectiveinincreasingpatientsurvival.

Insuchasituation,variouscombinationtherapiesarean effectivewaytotreatcancer Variousherbsandnatural supplementshavealsobeenfoundtoreducethesideeffects ofradiationandchemotherapy.Therefore,theymustbe usedincombinationwithradiationorchemotherapyto reducesideeffectsandincreasetheeffectivenessof treatment.Theproliferationofcellsthatleadtocancerleads totheneedfortreatment,andthefoodindustryevolvesto meetconsumerneeds.

Thedevelopmentofthefoodindustrycanbeidentifiedby thefactthat,afterstartingwithhealthpromotion,ithasnow

progressedtodiseaseprevention.Manymedicinalplants andphytochemicalscurrentlyinusearepharmacologically safeandareeffectivenutrientsininhibitingtumor progression,mitigatingthedamageofradiationand chemotherapy,andincreasingsensitivitytothesetherapies.

Researchersevaluatedtheeffectsofphenoliccompounds foundinAglianicograpepomace(GP)oncoloncancercell linesatdifferentdevelopmentalstagesafterexposuretoan invitrodigestionmodel.AglianicoGPextracthasbeen foundtohavestrongeffectsoncellproliferationand apoptosisaswellasothercellularprocesses.Significant increasesinBaxandBax/Bcl-2ratioandcaspase-3were observedinbothHT29andSW80cells.UHPLC-DAD analysisshowedthatanthocyanins,phenolicacidsand flavonoidswerethemaincomponentsresponsibleforthe increased(totalphenolics)TPCandantioxidantactivityin thedigestedextractofAglianicoGP.

NutraceuticalsinSkinTreatment

Itisknownthattheskinisthelargestorganinthebodyand itprotectsagainstallkindsofmicroorganisms,ultraviolet raysandalsochemicalsrelatedtosensitivity.Sincetheskin playsanimportantroleinprotectingthebody,itcanface changessuchasimmunodeficiency,photoagingand inflammation,whichcanharmhumanhealth.Apossible strategytoslowdownorreduceprematureagingoftheskin andalleviateskin-relateddisorderscanbefoundthrough theuseofnutrients.Thesenutrientscanbebioactive peptides,bioactivepolysaccharides,plantextracts, carotenoids,etc.Theadditionoftheseproductsinseveral humantrialsshowedfewersignsofagingaswellas protectionagainstUVaging.

WrappingUp

Overthepast10years,therehasbeenasignificantincrease inawarenessofnutrientsandtheiruseaseffective therapeuticsupplements.Nutritionalmedicineisnow acceptedaspartofcomplementaryandalternativemedicine (CAM)andthushasbeenincludedasanewbranchof CAM.Duetothedynamiceffectsoffoods(nutritionaland therapeuticeffects),theirpopularityamongthepublicand healthcareprovidershasincreasedcomparedtodrugs.

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Rebalance Health

Using the Science of Cortisol Rebalance to Optimize Life

Ifyouoftenfeeltired,fatigued,orasifyourlifeis

crashingdown—withouthavinganactualreasonfor it—thencortisol(yourstresshormone)couldbethe realculpritbehindit.Cortisollevels,whenimbalanced, couldleadtosuchfeelingsandimpacttheefficiencyofyour health.

Intoday'sfast-pacedworld,humanscannotaffordtotakea momenttobreathe.Weallwishtoremainstronger,active, energizedandrelaxedsothatthedemandsoflifecouldbe metefficiently.Whileseveralsupplementsappear promisingtomeetthishealthobjective,theyaredesigned onlytomitigatesymptomswhileignoringtherootcause (i.e.,yourcortisollevels)oftheailmentsthattheypurport toalleviate.

WhereasRebalanceHealthspeakstothecause—notthe symptoms—byhelpingthebodybalancecortisol.When takenwithregularexerciseandhealthynutrition,Rebalance Health'ssupplementalformulahelpsthebodyfunction optimallyeveryminuteoftheday.

UndertheleadershipofJustinHai,thePresident,CEO andCo-founder,RebalanceHealthischangingtheway peoplemanagehormonebalancethroughscienceand innovationofitsproprietaryDirectline™deliverymethod inRebalancelozenges.Whetheryouareanathlete,abusy parent,ormore,Rebalance'sSuperceuticals™areagame changerinrestoringabalancebetweenyourphysicaland mentalhealth.

InaninterviewwithInsightsCare,Justinspeaksindepth aboutthecompany'sobjectiveandeffortstohelppeopleto balancetheircortisolandfeellimitlessquicker.

Below are the highlights of the interview.

KindlybriefusaboutRebalanceHealthandthe developmentsorideasthatledtoitsinception.

RebalanceHealthhelpshealth-orientedhumansalways showuptoeverymomentat100%.Ourproductsincrease

performance,speeduprecovery,facilitateweightloss,and increaseconfidence,focus,sleep,andlibido.Weare technologicalinnovatorsfromthebiopharmaceutical industrywhosawnotonlyaneedforawellnesssystemthat workedwiththebody'sbiorhythm,butwantedtomakesure theingredientsneededtobringhormonebalanceactually gottowhereitisneeded.So,wedevelopeda proprietary deliverymethodtoincreasebioavailability

Pleasetellusaboutyourselfandyourprofessional journeysofar.

IamtheCEOandCo-founderofRebalanceHealth,born andraisedinLondon,England,andhavealwayshadan entrepreneurialspiritfromaveryyoungage.Utilizingthis

10 Best Companies in Nutraceucal Market 2023
Rebalance Health offers a Men's and Women's System that reduces elevated cortisol, the impacts of stress., and hormone imbalance. Our proprietary Directline™ delivery method makes it happen by providing 300% greater delivery of the necessary, natural ingredients.
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Justin Hai CEO and Co-founder of Rebalance Health

passionanddrive,IattendedHarvard,YaleandMITwhile earningadegreeinindustrialdesignfromtheRhodeIsland SchoolofDesign(RISD)andanMBAfromPepperdine. Matchingmydiverse,creativeeducationwithmy entrepreneurialDNA,Ihavestartednumerouscompanies withScottGlenn(Rebalance'sChairmanofBoardandCofounder)andhavebeenapartofWindermereVenture Capitalforthebetterpartof10years.Priortothat,Ihave alwaysbeenanentrepreneurworkinginandaround startups.I'veworkedwithlargeandsmallcompanies,from DisneytoAppletorealestate.

Whatarethecorevaluesofthecompany?Howareyou drivingthecompanytoachieveitsmissionandvision statement?

RebalanceHealthmoveswithaninnovativeanddynamic approachtohealth&wellnessthatprovidesacritical solutionforhumanbeingstofeellimitlessdailybybringing cortisolintobalance,reducingtheimpactsonthewhole body Wevalueintegrity,areresults-driven,andseektonot takeourselvestooseriouslyinanindustrythatiswaytoo seriousandlackstransparencyaboutwhatitpromises.Ifit movestheneedletowardabetterhealthoutcomeandcanbe substantiatedwithrealscience,thenweuseitinour productsandformulation.Ifitdoesn'tholdwater,wedon't giveitthetimeofday

WhatarethekeyproductsandofferingsofRebalance Healthandhowisitimpactingthedemographic concerned?

RebalanceHealthoffersaMen'sandWomen'sSystemthat reduceselevatedcortisol,theimpactsofstress,and hormoneimbalance.ThesecretoftheRebalanceSystemis inhowitsynchronizeswithyourdailybiorhythmaswellas usesDirectline™–aproprietarybiotechnology,providing 300%greaterdeliveryofthenaturalingredientsthatour bodiesneedtohelpmanagestressineveryaspectoflife. Ourthreepowerfullozengesconsistofthefollowing:

SLEEP-Dream

Ÿ Dreamhelpstolowerstresslevelsandracingthoughts, whichleadtodeeperrestorativesleep-butit'snota sleepaid.

Ÿ Itwasdesignedwithingredientstohelpyourbodymake themostofhormonerepairduringdeepsleep,soyou starteachdayprimedandrefreshed.

MORNING-LaunchforMen–ShineforWomen

Ÿ Ithelpstoraisecortisollevelsandkeepyoufocused throughoutyourday

Ÿ Thisisaperfectreplacementforyourmorningcoffee becausewhentakenregularly,youwillfeelmore energy,focusandsteadycalm.

AFTERNOON-PlayforMen– GlowforWomen

Ÿ Itcontinuestheworkbytakingtheedgeoffwithout losingyouredgesoyoucanmovefromworkmodeto playmode.

Ÿ Itkeepsyouinthegamesoyoucanstillhitthat workout,runthoseerrands,orgetsteamyinthe bedroom.

Combined,thesesupplementsprovidehormonebalance, thusreducingstress'simpactsdayandnight,while synchronizingwithyourbody'scircadianrhythm.

Howareyouusingemergingtechnologicalsolutionsto youradvantageandensuringsafeprocessesand products?Howisitrevolutionizingtheindustryyouare serving?

RebalanceSuperceuticals™lozengesarebackedbyreal science,pendingIRBreview,andquality-testedon13 differentlevels,includingmicrobiology,potency,andblend. OurSuperceuticals(superchargednutraceuticals)were createdbydoctors,scientists,andmedicalexpertsto formulatethehighestqualitysupplementsandundergo continuousthird-partytestingonspecificbiomarkersto ensurealevelofefficacythatexceedsmarketleaders' therapeuticlevels.PreliminarystudiesshowRebalance Superceuticalsare300%moreeffectivethanotherstandard supplementsthankstoourproprietaryDirectlinedelivery method.

Whatarethekeychallengesintheindustry?Howare youasaleaderturningthemintoopportunitiesto upscalethegrowthofyourorganization?

Cortisolhasbeenundertheradarforwaytoolongand highlymisunderstood.It'scausingsomanyoftheillnesses andissueswefacetodayasasociety,yetnobody understandstheirsymptomsarepossiblyaresultofcortisol imbalance.Manypeoplearejustgettingbyandonly beginningtorealizethatthereisabetterwaytolive. Stresslevelsareescalatingwitheverythingfromwork,

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money,housing,economy,family,etc.,weighingonallof us.Weknowstressincreasescortisol,asitshould,but ongoingstressmeansongoingelevatedcortisol.Thismeans cortisoloverpowersthebody'snaturalabilitytomakethe otherhormonesthathavebecomewell-marketed (testosterone,estrogen,melatonin,progesterone,hGH,etc.).

Managingcortisollevelshasacascadingeffectonthe productionoftheotherhormones,"rebalancing"your naturalchemistry.Inessence,ifyougetyourcortisolin line,thenallthoseotherhormoneswillcomebackonline, too.Thechallengeiseducatingapublicthatkeepstryingto fixsymptomsandnotrepairthecause.

Asanexperiencedleader,whatwouldbeyourwordsof advicetobuddingentrepreneurswishingtoenterthis industry?

I'veworkedwithlargeandsmallcompanies,inmany differentcategories,fromDisneytoAppletorealestate. WhenIadvisebuddingentrepreneurs,Ibelievethemost importantaspectsareapositive,can-doattitudeandasolid, strategicpath.

Fromanentrepreneur'smindset,it'sallaboutstaying positiveandpassionateaboutwhatyou'redoingbecauseit becomescontagious.Youneedtobeabletosay,"Nomatter what,Icandoit."Nevergivingupisoneofthemost importanttraitsanentrepreneurcanhavetobesuccessful. It'snotaboutrelishinginthehighsordwellingonthelows; it'sallaboutbeingeven-keeled;Iliketosay,"It'snotgoing tobeeasy,butit'sgoingtobeworthit."

Fromastrategicplanofattack,youhavetoknowwhatgoes nextandwhat'simportantintheorderofevents.Investors haveboughtintoyourvisionandtrustyouwiththeir investment,andemployeesarealsotrustingyouwiththeir careers,livelihood,andwell-being,soyouneedtobeable tonavigatethecompanycorrectly—whethertoslow thingsdown,rampthingsup,figureoutwhat'sworththe timeandeffortandwhat'snot,andbeabletomoveforward.

Whatareyourfuturegoalsforthecompany?Howdo youenvisionupscalingitsoperationsandreachin2023 andbeyond?

We'reworkingtofurthersupportourcurrentandfuture customerswithaccuratecortisoltestingthatmakessense. Thecurrentmentalityoftestingcortisolonceaday,oncea week,isverymisguidedduetotheinherentnatureoflevels

fluctuatingminutebyminute.We'vedevelopedtheMojo Meter™thatallowsindividualstomeasurethesubjective impactsofcortisolimbalance–sincethebest,non-clinical waytomeasurecortisolishowitaffectseverythingelse. Rebalancewantstoprovideverytargetedandspecific informationforindividuals,sopeoplecanrealizehowbest tolivelimitlesslyineveryareaoftheirlives.

Byprovidingtoolsandproductsthatunlockthesespecific underlyingissuesofsleep,recovery,focusandenergy,we canredefinewhatbeinghealthymeansforeveryone–that's whatIamexcitedabout,anditalignswiththemotivation I'vehadallalongwithhelpingpeoplefeelandbecometheir best.

February 2023 43|www.insightscare.com

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