The 10 Most Emerging Leaders in Healthcare, 2021 July2021

Editor’s Desk

AchievingClinical Goalswitha Cultureof Innovation

Healthcareisoneoftheessentialpartsofcareall

overtheworld.Noonecanaffordtobe complacentaboutone’shealth.Moreover,good healthisnecessarytobeaproductivecitizenofthecountry. Thus,withouthavingasoundhealthcaresysteminplace, nonationcanensuredevelopmentinthelongrun.Withthat beingsaid,thecontributionofemergingmedicalhealthcare leadersisofgreatsignificancefortheexcellenthealthcare systeminplace.

Nooneshouldunderestimatethevalueofgoodmedical professionals.Itisofutmostimportanceforanynationto havetalentedleadersinhealthcaretobuildthemostcapable healthcaresystem.Thecompetenceofmedical professionalsplaysaverysignificantroleingoodhealthof thepeople.Resourcefulemergingmedicalprofessionalsare thegreatestassetanynationcanhave.Theylead courageouslyandconsideratelytoensurethepatients'wellbeingthroughdeliveringgoodhealthcareservicestothe patients.

Today,havinggoodmedicaleducationalfacilitiesinthe nationisparamountforcreatingvaluableemergingleaders inthemedicalfield.Theinfrastructureofthehospitalswith allthelatestfacilitiesfordeliveringthemostcompetent medicalservicestothepeopleisoneofthemostsignificant pillarsofasoundhealthcaresystem.Alltheemerging healthcareleadersneedtobeinnovativetoplayavaluable roleinthispreciousservice.

Younghealthcareleadersaremostpassionateabout contributingtheirbestforthewelfareofhumansocietyby helpingthecitizensensuregoodhealthinallthewaythey can.Theyprioritizeachievingtheclinicalgoalsbydoing theirbest.However,educationisoneofthemostpotent toolsthatcanbeusedtochangethedynamicsofthepeople inanyfield.

Theemergingmedicalprofessionalsadaptscientific approachesintheirorganization.Theybelieveindelivering valuescientificallytothepatients.Theyadoptacultureof innovationattheirorganizationsinprovidingthemost pragmatichealthcaresolutionstothepatients.

Theyarecourageousaswellasconsiderate.Being courageoushelpsthemtoconfronteventhechallengesin thehealthcaresystemwiththeirconfidenceand competence.Whereasbeingconsideratehelpsthemtodeal withpatientsempathetically

Inthiseditionof“The10MostEmergingLeadersin Healthcare,2021”,wehaveenlistedsuchemerging healthcareleaderswhoareplayingasignificantrolein improvingthehealthcaresystembyleadingwithcourage andconsideration.

Featuringonthecoverofthiseditionisacompassionate leader,GregSavino,theFounder&CEOofBaybridgein 2015.GregopenedBaybridgewiththeideaofchange pushinghimforward.Hebelievesthatifeveryonein healthcarewastrulycommittedtopatientcare,theindustry willbeabletoprovidemorecost-effectivecarewithbetter healthcareoutcomes.Heaskshealthcareleaderstooperate underthisprinciple.

Unveilmoresuchstoriesofhealthcareleadersinthis edition.Also,whileflippingthepages,makesuretoread theCxOstandpointbyanindustryexpertandfascinating articlesdraftedbyourin-houseeditorialteam.

Let’sgetstarted!

sharad@insightssuccess.com

Sharad Chitalkar

FeaturedPerson

CompanyName

AudreySommerfeld

FounderandCEO

EliasChabtini

JumpToHealthInc jumptohealth.com

MedicaGroup medicagroup.com

Brief

JumpToHealth,Inc.,aimstoprovidemealplansandeducation oneatinghealthyfordifferentlifestylesandhealthconcerns.

MedicaTradingLLCiscommittedtoprovidingaesthetics, dermatology,anddentalmachinesandproductswhichmeetthe expectationsoftheinterestedparties.

BaybridgePharmacy Baybridge pharmacy.com

MichaelCollura President

MarcRippen CEO/Founder

Natalie

Fée Founder

InHomePersonal Services ihps.com

MarcRippen CEO/Founder

CitytoSea citytosea.org.uk

RoyFarfara MDFounder

TrioxNano trioxnano.com

RobertLauritzen CEO

RichardS.Isaacs CEOandExecutive Director

TomWhicher CEO&Founder

Cerebriu cerebriu.com

Founder&CEO GregSavino Founder&CEO DrDoctor drdoctor.co.uk

ThePermanente MedicalGroup permanente.org/

BaybridgePharmacyaddressestherisingcostofmedication andthechanginglandscapeofpharmaceuticalservices.

InHomePersonalServicesprovidesqualitycaretoseniorswho wishedtoremaininthecomfortoftheirownhome.

Alertgyfoundedbyasmallteamofinnovators,collaborateson challengingtechnicalprograms,specificallytoaddressthe highlydesiredabilitytomeasurebloodsugarlevelswithan externalwearablesensordevice.

CitytoSeaisanenvironmentalorganisationonamissionto stopplasticpollution.

TrioxNanodevelopsprogrammablebiologicnanocarriersthat areabletoaccuratelydeliverpayloadstotheirtarget.

Cerebriuimprovesworkflowefficiency,qualityandpatient outcomesindiagnosticimaging.

ThePermanenteMedicalGroups(PMGs)areself-governed, physician-led,prepaid,multispecialtymedicalgroups composedofmorethan23,000physicians.

DrDoctorisapatientengagementplatformthathelpstheNHS activatepatientsintheircareandincreasecapacitythrough waitlistvalidationandremotemanagement.

Greg Savino Founder & CEO Baybridge Pharmacy

AffordabilityisaconcernwithMedication. Understandingtheneedtoaddresstherisingcost ofmedicationBaybridgePharmacyischanging thelandscapeofpharmaceuticalservices.GregSavinoFounder&CEOopenedBaybridgein2015withtheidea ofchangepushinghimforward. “If everyone in healthcare was truly committed to patient care, the industry will be able to provide more cost-effective care with better healthcare outcomes”, guidesGreg. Gregaskshealthcare leaderstooperateunderthisprinciple.

Strong,Calculative,Persistent,&Realistic

Makingadecisionat16or17yearsoldthatpotentially pavesone’scareerpathisnoteasy.Fortunately,Greg Savinohadguidancefromhisfamilytodecidetopursuea degreeinpharmacy.Althoughhavingnohealthcare personnelinthefamilywhatsoever,selectingacareerthat canprovidefinancialstabilityforhisfuturewasvery influential.Heknewlittletonothingaboutpharmacyuntil afterstartingatStJohn'sUniversityCollegeofPharmacy fora6-yeardoctoratedegree.OnlythendidGregstartto workinapharmacyandlearnallthatgoesunseen.

DuringschoolasaPharmacyTechnicianandPharmacy Internandpost-schoolasaPharmacist,GregSavinospent 10yearswithWalgreens.Despiterapidgrowthtomanaging andoperatingthefrontstoreandpharmacyoftheirhigh revenuespecialtypharmacyintheBronx,thelimitations andrestrictionsenactedbyWalgreensdidn’tallowhimthe controlhedesired.In2015,afterjustafewshortyearsasa pharmacist,GregopenedBaybridge.Althoughstarting small,heknewwhatitwouldeventuallygrowinto.

PuttingCustomer-first

Gregasserts “I am driven by change and the process of enabling that change is building something from the ground up, exceeding expectations, and creating disbelief. These are all tied together.”

Gregtypicallydoesnotlookwithinthehealthcaresectorfor inspiration.Helookstohischildhood.Hisparentsarea hugepartofthereasonhehaslearnedtobecometheperson heistoday;kind,butstrong,calculative,butadventurous, andpersistent,butrealistic.

“A little story I like to tell people about myself is that as a child, the day after Halloween, every year I would set up a table outside on the sidewalk and sell all the candy I received the day before. I was a businessman before I even

know what that meant. In addition, I have also had two professional mentors throughout my career that have taught me the value of pharmacy and providing healthcare. One of which was my pharmacy manager when I worked in a corporate retail chain and still remain friends with today

At present, I constantly surround myself with like-minded individuals from whom I am always learning”,narrates Greg.

SuccessfulProgram

GregSavinoisalwayssearchingforsolutionsforaconstant issueinhealthcare–cost.InDecemberof2019,herolled outSpartaRxPrograms,aseriesofprogramsdesignedto givethepatient’safixedlow-priceassuranceontheirout-

of-pocketcost.BaybridgePharmacy’smostdominant revenuestreamstemsfromSpartaDermatology,its programspecificallyfortheDermatologymarket.

Greg’steamhassuccessfullycreatedthisprogramforevery patient–young,elder,insured,uninsured,etc.–wherethey canreceiveanymedicationfromtheprogramfornomore than$24.Thatlistcurrentlyoffersover60medicationsthat cantreatsomeofthemostprevalentconditionswithin dermatology,includingacne,psoriasis,eczema,and rosacea.BaybridgePharmacyhasalargesalesteamand takesaclassic,boots-on-the-groundapproachinmarketing itsprogramtophysicians.Theresponsehasbeen outstanding,withoverathousandactiveprescribersatany giventime.

CommunicationwithEveryPatient

BaybridgePharmacydoesnotoperatewithanabundanceof advancedtechnology That’sjustnothowitworkswith them.Thecompanyoperateswiththesameelectronics equipmentthatmostotherpharmaciesalsooperate.The differenceisthelevelofservicetheyprovide.The organizationisattentive,communicative,responsible,and honest.Theseattributescombinedwithathoroughbusiness planhavecreatedsubstantialoutcomes.

BaybridgePharmacycommunicateswitheverypatientby eitherphone,text,orinperson.Italsomaintainsgood relationshipswiththeprescribersthatactivelyusethe serviceforitspatients.

Time-efficientandInterpersonalSkills

TakingGregSavino’sknowledgeandexperiencefromthe retailpharmacyandapplyingittoatechnologycompany thatwillhaveavasterimpacthasbeeninprogressforafew yearsalready.Greglovesretailpharmacy,buthisreachis limited.Hewantstocreatechangeinhealthcareina positivewayandhewillachievethatthroughInfinityRx,an emergingPBA(PharmacyBenefitsAdministrator)with advancedproprietarytechnology.AlthoughBaybridge Pharmacyisnotatechnologicallyadvancedcompany,Greg seesthevalueoftechnologyinhealthcareandisdrawnto thoselookingtobettertheindustry

InfinityRxisamulti-facetedcompanyoffering: Data,viavastreportingsolutionsforpharmaceutical •

manufacturersandotherpayorstoensureproper financialassistanceprogrammanagementandlegal compliance.

Fraud,waste,andabusemonitoringtoensureprogram • participantsareabidingtoprogramguidelines. Asuiteofoptions,forpharmaceuticalmanufacturers, • withmedicationdistributionchannelsandpharmacy networks.

ClassicApproachwithModernThoughtProcess

Overtheyears,BaybridgePharmacyunderwent3 renovations;2-withinthecurrentwallsand1-takingover aneighboringstorefront.Withthisgrowthinbusiness, cameagrowthinstaff.Culturingateamtobecommitted andfocusedonpatientcare,whilealsobeingconsciousof

themonetarysuccessofthebusinessisthegreatest achievementtodate.Adaptingduringextremelyvolatile yearsintheretailpharmacyindustrywasessential.Profit marginswerecutrazor-thin,auditsfrompharmacybenefit managers(theveryprofitablemiddlemeninpharmacy) wererelentless,andthecompetitionwasattemptingtocopy andimplementBaybridge’smarketingideologyintotheir businesses.

Despiteallthat,BaybridgePharmacy’sabilitytoexecuteis theprimaryreasonitcontinuedtogrow.By2019,itwas th rankedthe46 fastestgrowinghealthcarecompanyinthe UnitedStates.Itwasthenthattheattentiononthecompany startedtobuild.Bylate2019,thecompanyenteredan acquisitionagreementwithanemergingprivateequity firm’spharmacydivision,OptioRxthatwouldcloseinJune of2020.

BaybridgePharmacyrolledoutitslatestmarketing endeavorinDecemberof2019,SpartaDermatology,to BaybridgePharmacyaswellastwootherNYpharmacies undergoingacquisitionbyOptioRx.Thisgivesitsprogram greatergeographicreach,nowspanning3statesandover 30counties.Thecompany’snextmoveistakingSparta DermatologytotheWestCoastandimplementingthe programinOptio’sCaliforniapharmacies.

The 10 Most Emerging Leaders in Healthcare, 2021

Audrey Sommerfeld Founder, and CEO Jump To Health, Inc.

Audrey Sommerfeld

Helping People Radically Change their Health through Science of Sound Nutrition

Thesoundbodyistheproductofthesoundmindand soundnutrition.Havingahealthymindandhealthy nutritionplaysthemostimportantroleinthe overallhealthydevelopmentofpeople.Itisbelievedthat mentalhealthandphysicalhealthareinterrelated,and Healthydevelopmentofpeoplemeanshavingphysical fitnessandmentaltoughness.

“All health challenges can be improved by good nutrition,” believesAudreySommerfeld,ahealthcareleader.Having spent3decadesincompaniesandstartupsacrossnutrition, wellness,skincare,andOTCmedications,Audreyis committedtohelpingpeoplelivebetterlives.Currently,she istheFounderandCEOofJumpToHealth,Inc.,a companyaimingtoprovidemealplansandeducationon eatinghealthyfordifferentlifestylesandhealthconcerns.

ATakeonToday’sHealthcare

AccordingtoAudrey,healthcaretodayisabouthelping thosealreadysicktryingtogetbetterormanagetheir illnesses.Shehopestobegintoshiftasasocietyto prevention–tomoreeducationontheroleofnutrition.She expresses, “Today our physicians and health workers get very little education on nutrition – some sites say 8 hours or less in their career. We don’t teach this in school either. So consumers rely on the food industry to tell us what is healthy, and it is impacting our weight and our health. Sugar is cheap, it is addictive, and it is in all of our food, and it is making us sick.” Itwasthisrealizationthatledher toformJumptoHealthInc.

JumpToHealthisfocusedoneducationandahealth Journey–tohelpinspirepeoplewithinformation, recipes,toolsacommunityofsupport,recognition, andrewards.Ithasa12weekJourneyguarantee becauseonceyoustartonthepathtobetterhealth–yougetinnerfit.Yourhealthimprovesfromtheinside outandJumpToHealthdoesthiswithproductsbased onsoundnutritionscience,notonhype.

HelpingPeopleTakeChargeofTheirHealth

Audreyopinesthattoday,wearebombardedwithtv commercialsandinformationthatmakesitconfusing toknowwhatishealthy,andourdietsareloadedwith sugar.3outof4adultsareoverweight,andalmost1 in2areobese.Andourkids–aresufferingasaresult. Today1in3kidsareobesesettingthemupforshorter lives.Diabetesisnowbecomingachildhooddisease insteadofadult-onsetdiabetes.DiseaseslikeDiabetes, Cancer,Gallstones,FattyLiverDisease,Gout, Arthritis,HighBloodPressure,StrokeSleepApnea, Asthma,andotherhealthissuesareontherise,andall arerelatedtobeingoverweight.ADHDisnowa householdname.1in20kidsarealreadyon medicationformoodandattentionissues.ADHDhas grownover500%sincethe1980s.Heartdiseaseis becomingayoungerandyoungerissue–andexperts predictthattoday’skidswillhaveheartattacksas youngasage30.

Audreyfirmlybelievesthathealthynutritioncanplay abigpartinhelpingfightthesehealthissuesandJump

ToHealth™isheretohelp.ItoffersaHealthJourney–and itstartswithprovidingahealthybreakfast.Ithelpswitha betterbreakfast,bettertoolstohelppeopletakebackcharge oftheirhealth.

JumpToHealth’sbighairygoalistoendsugaraddiction, obesity,diabetes,inflammation,andallhealthchallenges thatcanbeimprovedbygoodnutrition.Itdoesthisby providingeducationonnutrition,simpleproductsolutions andkits,andmealplans,programs,andrecipesforfreeto itsmembers.

ProvidingHighestQualityProteinRichFood

Audreymentionsthatproteinqualityintheproteinshakes makethedifferenceandJumpToHealthhasauniqueTriSorbProteinBlend™tobetterbuildleanmuscle,boost immunehealth,andhelponefeelsatisfied.Itcombinesthis withpatentedandclinicallystudiednutrientsshownto boostmoreproteinintoone’sleanmuscle+45%morewith aspecialaminoacid,and+25%morewithaspecial botanicalherb.Allthishelpstomakeiteasytodigestfor youngandoldalikeandgiveathletesbetterperformance too.Andwithapatented,clinicallystudiedprebioticfiber–showntohelpboostguthealth,moodandfocus.

Moreover,Audreyalsosharesthattoday,1in2kids,and2 outof3adultsarenotgettingenoughcalciumforstrong

bones,teeth,muscles,andhormoneregulation.Thenews showmorekidsaregettingbrokenbonesasaresult.Thisis whyJumpToHealth’s‘ShakeThatTastesLikeCake™’ alsoincludesnutrientstoaidmorecalciumabsorptionup–upto50%more.Anditsspecialproprietarysweetener systemisclinicallyshowntohelpbloodsugar,helpathletes havebetter-sustainedenergyandperformance,andhasfatburningpropertiestoo.

PracticalExamplesofImprovementinHealthofPeople

TravisBlackwasoverweight,nothappywithhimself,he wasprediabetic(A1Cwas6.4),histriglycerideswerehigh, andduetoaworkinjurywasnotabletoexercise.With JumpToHealthnotonlydidhelose50poundsandgofrom a55”waistto40”,butalsohisA1Cisnow5.1andhe loweredhistriglycerides100points.

JulieSnowbargerandherhusbandMarkhavemade significantstridesintheirhealth.Juliehaslost50pounds andgainednewenergy,andMarkhaslostweighttothe pointwherehisdoctorremovedhisbloodpressure medications.

ValuingVarietyofIdeasandInputs

Audreysaysthatteamwork,thoughtfulchallengingof beliefs,passionforchange,andtransparencyineverything isimportantasabusinessleader.Shebelievesthatmore brainsarebetterthanonebecauseagoodideacancome fromanywhereoranyone.

PeopleatJumpToHealthtrytolisten,takeconstructive feedback,andcreateateamculturewheretheyvalueideas andinput.

TakingGuidancefromPeopleWhoTellstheTruth

Inheradvicetoemergingentrepreneurs,shesays “Your greatest competition is within yourself, and when you focus on the greater benefit for the consumer, you both win. During my career, I had many great mentors and I think it is important to find those people you can rely on to tell you the truth, to be a good sounding board, and who hold you accountable to be the best that you can be. Push yourself to learn, to listen, and never stop growing”

HelpingMillionsofPeopletoHaveaHealthyLiving

Inthenextfiveyears,JumpToHealthhopestotakeits missionglobal.Obesityandhealthissuesaregreataround theworld.Infiveyears,ithopestodramaticallygrowits companyanditsmissionandtohavemillionsofpeople sharetheirjourneybacktohealthylivingwithothers.It offersgreatword-of-mouthincentives,anditsgoalisto helpwholefamilies,communitiesradicallychangetheir futurehealthstartingtoday.

Leading COMPANIES

World's Who's Who, Tech Innovation Global Inc. announces a $200 million funding round July 16, 2021 technology

Tech Innovation Global Inc. founder Alicia Carroll, an engineer, who performed COVID-19 data analysis to be honored among the World's Who's Who, July 21, 2021, an edition once every five years, she will be honored for her work in COVID SARS CoV 2 emergency. It will feature her success stories, life challenges, emotional upheavals, leadership qualities and represent global collaboration, despite many odds, in most grandeur form, coming out triumphant from the world crises while highlighting its pillars of who have helped the world stand in 2020. Alicia Carroll performed COVID-19 analysis, supply capabilities, training in communicating technical issues, processes to improve implementation of guidelines including face mask mandates and alliances. Tech Innovation Global Incorporated will also feature companies, GenConnect recruiting to global workforce solutions, travel, health to vital living and products.

Honors include Global Leaders LLC, CIO Magazine and feature in the British Chamber of Commerce. Alicia Carroll is also nominated as advisor to a foreign chamber.

Tech Innovaon Global Inc. announces a $200 million funding round on July 7, 2021 in collaboraon with the Beer Business Bureau, companies and SCORE Mentor www.score.org for technology iniaves during 2021 to 2031 (10 years). You can go to https://www.techinnovationglobalinc.com to invest or sponsor community programs and pay for services featuring: Ÿ Seerletics fitness app seerletics.com

GenCennect Recruiting

Tech Innovation Global Incorporated techinnovationglobalinc.com

Enviroculture and Agriculture

Travel app-based services and Promotion of Health

Community activities (Museum, Calvary Hill, Libraries)

You can also pay for other services or requests at https://techinnovationglobalinc.com/product/request-services/.

Technological Advancements in HEALTHCARE

Weliveinadigitalera,wheretechnologiesare emergingfasterthanwecanevenexperience.

Humanityhascomealongwaytomakeliving betterineverymannerpossible.Asmuchastechnological advancementshavechangedtheindustrialandeconomic sectors,thegame-changingimprovementsinhealthcareare immense.

Theever-improvingtechnologyinthehealthsectorhas savedcountlesslives.TherightinventionofX-ray machinestoadvancedsurgicalpracticesandtheutilization ofArtificialIntelligencefurtherdevelopsexisting technologiesthatcanbegroundbreakingtomaketreatments moreaccessibleandincreaselifeexpectancies.

InnovationsinHealthcareTechnologies

Thepandemichasdisruptedlivesaroundtheglobe,creating chaosandfearofdemise.Thoughvaccinesarebeing developedatarapidpaceanddeliveredworldwide,itisof utmostimportancetostaysafeandtakenecessary precautions.Overthepastyear,itwaspossibletoidentify andtreatthesymptomsofthemostprimarycasestothe mostsevereduetoadvancedtechnology.Inthelastdecade, manydisruptingtechnologieshaveemergedwithnothing butthepatientinmind.

InformationTechnology:IThasavailedhealth practitionerstostoreandretrievedatarelatedtopatient's healthrecords,enhancingpatientinformationthrougha

legibleformatthatiseasytouse.Thesedatahelpin consultingthepatientanddiagnosingthedisease,reducing thechanceofmedicationerrors.Additionally,alertson medicationcanhelpinadheringtospecifictreatmentsand schedules.Therecordeddatacollectedcanleadto uniformityofpracticeacrossallhealthpractitionersand improvecommonconditionsbasedonpastdossiers.

3DPrinting:3Dprintinghasavastnumberofapplications, butitisusedtocreateimplantsorjointsforsurgeryinthe medicalfield.Itisfrequentlyusedindevelopingprosthetics asitcanmakeperfectmatchinglimbs.

Robotics:RoboticSurgeryhasbeenaroundforawhile. Roboticsprovidesprecision,flexibility,andcontroltoa surgeon'shandtooperateasnon-intrusiveaspossible.

VirtualReality:TheusageofVRdeviceshasincreasedat anacceleratedpace.Particularly,VirtualRealityhashelped medicalstudentshaveavirtualexperienceofreal-life proceduresandabettervisualunderstandingofhuman anatomy

Wearables:Whatbeganasafitnesstrackertotrackheart ratehasspreadwidelyinbecomingapotentialdeviceto preventoralertsevereconditionsbeforehand.

Patientsfocusonpreventionandmaintenance,demanding informationabouttheirhealthmorefrequentlyintoday's digitalage.Healthcarecompaniesinvestinwearable

devicesthatcanprovideupdatedmonitoringofpatients determiningtheplausibilityofhealthmishaps.

Atweakinwearabletechhasallowedeventodetect cardiovascularanomaliesearlier Wearablescanalsotrack calorielevels,hydration,andevenbodytemperature.A sweatmetersdetectorisusedforpeoplewithdiabetesto monitorbloodsugarlevels.Oximetersmonitortheamount ofoxygencarriedintheblood,oftenusedbypatientswith respiratoryillnesses.

ArtificialIntelligence:ArtificialIntelligence(AI) representstheepitomeofmedicalinnovation.Healthcare canbestimplementAIinareaslikeprecisionmedicine, drugsdiscovery,andgenomics.

AIcanpowerasophisticatedpatternrecognition,whichcan beavailedtohavepersonalizedtherapiestailoredaround thegeneticsandlifestyleofpatients.Biotechand pharmaceuticalcompaniesarealreadyusingmachine learningalgorithmstoshortenthedrugdevelopmentcycle.

Nanotechnology:Nanotechnologyisonthevergeofa transformationalchangethatcanoperateasaprecisedrug deliverysystemusingnanoparticlesandnanodevices.The so-callednanomedicineagecouldbecapableofbecoming cancertreatmenttoolsorminusculesurgeons.Though

smartpillsarealreadyusedforcolonoscopy,itwon'ttake longtoseemorepracticalnanotechnologyapplications.

FeedingyourThoughts

Themerethoughtofvirtuallyvisitingadoctorfrom hundredsorthousandsofmilesawaywouldhavebeen difficulttobelieveafewdecadesago.Fromremote monitoringtoolsandwearablemedicaltechnologyto nanotechnology'sprecisedrugdeliverysystem,healthcare hasevolvedrapidly.Healthcareisasectorthatrequires highlyskilledindividualswithyearsofstudy;italso demandsinfrastructureandtools.Therobustinnovationin healthcareischangingthelandscapeoftheindustryevery year

Theadventofinnovativetechnologieshasmadedigital healthplausible,whichhavebeenprovenrevolutionaryin healthcare.Theprobabilityofinnovationinhealthcareis vast,andwecanexpecttechnologiesthatcangradually increaseimmunitytominimizeminorillnesses,infections. Thefutureofhealthcaremoveshandinhandwith technology;wehavetoprepareforthechangingworld, whichistheonlywayforward.

Michael Collura

Manybusinessesarebornfromthenecessityto

meettheneedsofthecustomers.ForMichael Collura,itwasaboutmakingpersonal connections,buildingrelationships,andgivingtheclients thechancetomaintaintheirindependence.Heisthe PresidentandCEOofInHomePersonalServices,oneof thelargesthomecarecompaniesinIllinois,andgrowing throughouttheUnitedStates.Heenjoyshisrolenot becauseofthesuccess,butbecauseofthefactthathis successisenjoyedbysomanyothers.Michaelhas surroundedhimselfwithtalentedindividualsthatmakeup inareaswherehefallsshort.Hebelieveshisteamisthe secrettohiscontinuedgrowthandsuccess.Withsucha talentedteambyhisside,hedecidedtoexpandthebusiness intoafranchisesystem.Todayheisofferingentrepreneurs theopportunitytobeapartofthisamazingbrandand history.

ALeaderwithStrongBusinessSkills

InHomePersonalServicessetouttobeaninnovativeand forward-thinkingcompanyfocusedonqualitycaretothe seniors.SincedayoneMichaelandhisteamhaveproudly servedthecommunitywiththosesamevalues.“We are here to provide care to seniors, veterans, and persons with disabilities. In Home Personal Services sees the industry, our opportunity, and our place within the industry in a very different way. I guess that is what makes us a leader”, says Michael.

AReliableHomeCareProvider

IHPSservicemodelsincludeawidearrayofcareoptions thatarealltailoredtomeettheindividualcareneedsof thosewhohavetrustedthecompanysince2004tobetheir provider Theteamprovidesthecarethatisneeded.No long-termcontractsorcommitments,nohourlyminimums, nosurprises.Whatmakesthecompanystandoutthemostis

thewayithasdeveloped,trained,anddeliverthecare.It hasseenchallenges,needsofthoseitcaresforaswellas theirfamiliesandthehealthcaresystemasawhole.The companyhasdevelopedmanyadvantageswithinthe franchisesystem,anditenjoysbeingabletobringthe differenceinthecareitprovidestothecommunityand clients.

RiseandShineintheTimesofPandemic

Michaelstatesthatduringpandemiccrisis,thosewhowere onthefrontlinesofthecompanywerenotwillingto surrendertothetaskfacingthem.Ithasbeenatragic exampleofcourageandhope.Therewerecountless caregiversandcareproviderswhoknewaboutalltherisks theywerefacingwithCovidandtheyneveraskedtobe reassigned,taketimeoff,orabandontheseniorswho trustedIHPS.Thesecaregiversandfrontlinesdidn'tjust ensurethesafetyofthosewhoaremostvulnerable,they alsoensuredIHPSasabrandkeptitspromise.Whilean unspeakabletragedyforsomany,itwasalsothemost inspiringyearforInHomePersonalServicesbecausethe company'sfront-lineworkersneverbackeddownandthey neverstoppeddoingwhattheyneededtodo.Theyknewthe dangerandstill,theyperformedtheirdutiestoensurethe livesofothersweremadesafe.Thatwastruecourage.

Covidisaspermanenttothehealthcaresystemastheflu.It ishereforever.IHPShasalreadydevelopednewprotocols andtrainingtoensuretheongoingsafetyofthoseitcares for.IthasdevelopedawhollyuniqueandproprietaryAcute HomeCaresystemforthedeliveryofcarethatmeets pandemicstandardsforsafetyandinfectioncontrol.The organization'sabilitytocareforthesepatientstoday, tomorrow,andthose“longhaulers”isalreadyinplaceand whileithopestoneverhavetoproveitsabilitytodoso,it isreadyforthenextpandemicineverywayitcanpossibly be.

ATakeonLeadership

WhilesharinghisthoughtsonleadershipMichael emphasizesonIntegrity. IntegrityisasignificantpartofIn HomePersonalServicesanditsleadershiptraining.For Michael,itisthesinglemostimportanthumanattributethat isoftenthemostelusive. “Having true integrity today in our world would bring about the radical change that unfortunately most of our population is unable to recognize, acknowledge and achieve,” Michaelasserts.

RemovingObstaclesforOthers

Inhisadvicetoupcomingentrepreneurs,Michaelsays “First, do it because you care. This is not a business for those without a genuine desire to care for others. Second, do it your way. If you want to lead, then forge your own

path. I speak to prospective franchisees all the time and they ask me about the growth and success of other franchisees we have. My response is simple. Do you want to work up to their potential or your own? While some may see the value in benchmarking themselves against others or see this as a means to measure their own potential. I see it as a limitation you already entering into.”

Headds, “I say nothing about what I have achieved was done because I cared about what others were doing. I made my own path and today we are a brand being recognized in this article for just that. Nothing about us that is unique or innovative would exist if we just followed suit and worked to be like everyone else. Finally, embrace failure. If you find that word to be upsetting, you are not ready to be an entrepreneur. Because those of us that truly succeed first had to fail.”

‘‘

“Provide quality care that is affordable and worry-free.”

Michael A Collura, Founder & President In Home Personal Services

Robert Lauritzen CEO & Co-founder Cerebriu

RobertLauritzen

AnArdentLeaderonaMission

AccordingtoWHO,nearlytwo-thirdsoftheworld’s populationhasnoaccesstodiagnosticimagingdue towhichpeoplearesufferingneedlesslyfrom preventablediseases.Accesstodiagnosticimagingservices hasagreatimpactonpublichealthwiththecreationof imagesofinternalstructuresusingX-raysorotherphysical waves,suchasultrasoundandelectromagneticwaves. Unfortunately,currentshortagesofhumanresourcesand obsoleteorbrokenequipmentaremakingitdifficultfor radiologistsandbiomedicalengineerstoprovideadequate accessinthecreationofsuchimages.

Withamissiontotransformradiologybyprovidingbetter toolsforradiologistsworldwide,RobertLauritzenteamed upwithAkshayPai,MadsNielsen,MartinLillholmand ErikDamtoformCerebriu,acompanythatimproves workflowefficiency,qualityandpatientoutcomesin diagnosticimaging.

RobertisaninternationalITlifesciencesexecutivewith 25+yearsofmanagementexperienceacrosshigh-tech MedTechstart-upsandlargecorporationsacrosspharma andITserviceproviders.Hehasheldvariousleadership rolesfordifferentpharmaceuticalcompanies.

DedicatedtotheDevelopmentofRadiology

CerebriuisanAIradiologycompanyautomatingMRI workflowsforfasterandpersonalizeddiagnosticimaging. Thecompanyimprovesworkflowefficiencyandqualityat thepointofcare.Itssoftwaresolution,CerebriuApollo, achievesthisbyautomatingMR-imageacquisition protocolsandtriageduringexaminationprovidingdecision supportatkeystagesofthediagnosticprocess.Ultimately, thisresultsinimprovedproductivity,prioritizingtheright patientsattherighttime,andlessstressforclinicians.It

toTransformRadiology

aimstodemocratizeradiology,byenablingmorescanning andmorepatients,withoutburningouttheincredible radiologists.

“I believe we must rethink radiology to help a vastly growing global need for medical imaging-based diagnostics, and we can make a significant difference transforming the workflow using advanced technologies of our era,” saysRobert.

BringingaRealDifferenceinPeople’sLives

Apollobringstheinnovationofsmartprotocolinrealtime enablingadaptingscanningprotocolsbasedonthefindings ofinitialsequencesacquiredorcutshorttheexamination withnofindings.

Makingbreakthrough healthtechrequires extremeadaptability, resilience,andpatience. Createvalueforyour usersandcustomers everyday.

The 10 Most Emerging Leaders in Healthcare, 2021

Talkingaboutsociety,thatincludesreducednonacute admissions,potentiallyimprovedhealthoutcomeswiththe prospectofthesmallerlengthofstay,reducedthechemical contrastgadoliniumconsumptionandcontrastwaste managementcosts,completescanningofstrokemimics, earlydetectionofstrokechameleons,ahigherdegreeof interventionandlateranyneurologicaldisease.

ImpactofPandemic

Sharinghisviewsontheimpactofpandemic,Robert mentionsthatitshowedhimandhisteamtwothings.One istheneedforprovidingthenecessarytoolsforclinicians todealwiththeincreaseddemandforhealthcare.Asof now,radiologycannotkeepupwiththeincreasedemand forneuroimaging.Robertandhisteamhaveseenthatthere isanincreaseinstrokepatientsduetothepandemic,yetnot enoughradiologiststocopewithit,that’sahugethreatto itshealthcaresystemandsociety.

Thesecondthinghementionsistheneedforunlockingthe powerofdatainordertoprovidebettercare.Themore hospitaldataisshared,themoreitcancapitalizeonAIto reducethebottleneckinthehealthcaresystemandprovide betterhealthcare.

SimplifyingRadiology

IntheopinionofRobert,thefutureofhealthcareismedical professionalsaugmentedbyAI.Hefurtherstatesthatevery hospitalgeneratesaround50petabytesofdata,yetlessthan 3%isactionable,analysedandused.Ifitmanagestobetter capitalizeonthatdata,undoubtedlyopportunitiesarise.AI willnotreplacetheroleofclinicians,butratherboostthem, relievingthemofmorestraightforwardcognitivetasks,to letthemfocusoncaseswheretheirexpertiseisneededthe most.

TheteamsatCerebriuthrivewithdiversityandequal opportunities.Halfofthecompanyhaveforeign backgrounds,andmorethanathirdarefemale,whichis prettygoodinatechstartup.

ATrueHigh-PerformanceTeam

Cerebriubringstogetherthesmartestbrainsinthefieldof AI/MLwithadistinctpurposetoimpacthealthcareinthe world.Eachoneofthemanagementteamhasaminimum ofadecadeofexperienceintheirfieldofexpertise. Moreover,Denmarkhasbeenrankedasoneofthehighest AIreadinesscountriesbyOxfordInsightsandthe InternationalResearchDevelopmentCentre(IDRC).

BestAdviceforanearlystartup

Inhisadvicetoemergingbusinessleadersaspiringto ventureintothehealthcarearena,Robertsays, “Learn fast. Fail fast. Embrace the challenge and pivot instead of clinging to an idea, that just does not work. Ensure to surround yourself with talent who could go on this journey with you when it’s great, and when it’s challenging. You will hear many times the word NO, but with courage, dedication, and patience, your chances of hearing YES are much higher.”

Adventures in

Natalie Fée

Natalie Fée

In2014IwasworkinginTV,gettingabitfedupwith

thelackofcoverageofenvironmentalissues.Around thattime,IwasscrollingonFacebookandcameacross thetrailerforthefilmAlbatross.Isawthemostbeautiful, fluffiestAlbatrosschicks,dyingofstarvationintheirnests withtheirbelliesfullofplastic.Itwasheart-breaking;Iwas totallydevastatedandfeltagriefunlikeanythingI’dever experiencedwhenseeinghuman-causedenvironmental issues.Ithinkitwassomethingaboutseeingeveryday itemsthatIused-mybrandoftoothbrush,inkcartridges, bottlecaps-literallycausingthedeathofsomethingso magnificent.AndIknewinthatmomentIcouldn'tjustsit backandallowthistohappen.

FromthatdayonIsetaboutdoingsomethingaboutit.Ihad noideaCitytoSea,whichbeganwithamusicvideo,would goontobecomeoneoftheUK’sleadingvoicesonplastic pollutionorthatourcampaignswouldhaveasignificant impactonreducingpointlessplasticsonthehigh-street,in supermarketsandatgovernmentlevel.

Frompetitionsandmediacampaigns,tograssroots communityactionandeducationinschools,ourworkstops hundredsoftonnesofplasticfromgettingintoour ecosystemseachyear.Forexample,in2016weranourfirst consumercampaign.Itwasasimpleask,forallmajor retailersintheUKtostopsellingplasticcottonbudsand switchtopaperinstead.Whathappenednextwasatidal waveofpeoplepower

Over150,000signedapetitionandsoonmajorretailers wereresponding.Beforelongallnineofthemajor supermarketshadpledgedto#SwitchtheStick.Thismeans thatsince2017over420tonnesofsingle-use,nonrecyclableplastichasbeensavedannually.In2020theUK governmentcaughtupandcompletelybannedplasticcotton budstickswithsimilarlegislationexpectedacrossallofthe EUbythissummer

Leadershipis,ifanything,aboutcreatingimpactandCityto Seaarecertainlydoingthat.

CitytoSeastartedasanideainmyheadonariverbankbut hassinceevolvedintoaglobalcampaigningorganisation withdozensofmembersofstaff.Sincethoseearlydays we’vesavedhundredsofmillionsofpiecesofplastic throughawardwinningcampaigns.Attheheartofallof thesecampaignsisbehaviourchangeinsightandscienceto inspireanddrivechangefromthegrassrootsup.Making surewehaveimpactinallwedo.

Learningfromtheearly#SwitchTheStickcampaign,what weadvocateforarepositivesolutionsmadeeasy.For example,oneofourmostsuccessfulcampaignsRefill, showshowyoucanswaptheeasyconvenienceofbuyinga single-useplasticbottlewhenyouareoutandabout,toa freeRefillfoundthroughourgeo-locatedappthattellsyou whereyoucaneat,drinkandshopwithoutthepackaging. Makingswitcheseasyisandshowinghowtheycanbedone isabigpartofwhatwedo.Sohereare3simplestepsfor youtotaketowardsplastic-freeliving.Andremember,you aren’ttakingthesestepsalonebutaspartofaglobal movement.Andwhenyoutakethesestepsyouarenotjust stoppingplasticpollutionbutyou’reinspiringotherstodo thesame.

1. Doaplasticaudit

Knowledgeispower.Whenyouarecuttingbackonthe amountofplasticyouuse,doaplasticauditandcollect yourwasteforaweek.Thisnotonlyhelpsyougetafeelfor whatyou’reusing,butyoucanalsostarttocutouttheeasy toreplaceitems.

OurfriendsoveratEverydayhavecreatedasupersimple programmewitheverythingyouneedtoaudityourwaste forweekandunderstandwhatyou’reusing,andwhatthe impactofthatwouldbeoverayear Afterdoingthis,you canstarttothinkabouthowyoucancutouttheplasticthat youusethemost.

2.ChoosetoReuse

Weareproudtoenableyoueat,drinkandshopwithoutthe plastic.It’stimetoavoidusingdisposable,single-use cultureandchoosetoreuse,asthereareplentyofreusable optionsoutthere.Ithasnowbecomeeasytoreduceplastic footprintwithoutbreakingthebank.

3.GoRoomtoRoom

Themoreyoulookaroundyourhousethemoreyousee single-useplastics.Frombathroomcleanerstothe vegetablesyougotthesupermarket.Plasticgets everywhere.Butwhetheryourworriedaboutnappiesor nectarineswe’vegotyoucoveredwithourplastic-free livingguide.

Thetidesareturningonplasticpollution.Moreandmore peoplearemovingawayfromharmfulsingle-useplastics.

Astimehaspassedmyroleasaleaderincampaigningon plasticshaschangedfromoneofneedingtoinspireand energisepeopletooneofchannellingpeople’senergy(yes peoplelikeyou!).Peoplearedemandingchangeand businessesandgovernmentsalikearebeginningtositup andnotice.

It’snowallofourjobs,asleaders,tokeepthepressureup andtomakesurewemaketrulysustainablechoicesaway fromsingle-useplastics.

Andifyou’vegotplasticsnailed,youcantakeyourjourney furtherandhaveareadofmylatestbook,HowtoSavethe WorldforFree,whichhashundredsofwaysyoucan protectnotjustouroceans,butourentire,preciousplanet. Justinmylifetime,we’velosthalftheworld’swildlife. HALFofit.Gone.Andit’sourresponsibilitytomakesure wedon’tlosetheotherhalf.

AbouttheAuthor

NatalieFéeisanaward-winning environmentalist,authorofHowtoSavethe WorldforFree,keynotespeakerandfounder ofCitytoSea,aUK-basedorganisation runningcampaignstostopplasticpollutionat source.

RoyFarfara MDFounder

TrioxNanoLtdIsrael

“Realtimeprogrammingisthelogical evolutionofmedicine”

TrioxNano Creating Better Medical Solutions by Developing Programmable Nano Carriers

Healthcareindustryisoneofthemostimportant industriesamongallindustriesintheworld. Ensuringthegoodhealthofpeoplebyapplying thelatestadvancesintheindustryisanimportantgoalall medicalinstitutionsandleaderspursueinthisfield. Technologicaladvancescanbeincrementalordisruptive. Ofthedifferenttechnologiesinthehealthcareindustry NanotechnologyandspecificallyDNAnanotechnologyis holdingthegreatestpromiseforhealthcareindustry's disruption.DNAisthemoleculethatstoresandtransmits geneticinformationinbiologicalsystems.ThefieldofDNA nanotechnologytakesthismoleculeoutofitsbiological contextandusesitsabilitiestoassemblestructuralmotifs andthentoconnectthemtogether Thisfieldhashada remarkableimpactonnanoscienceandnanotechnology,and hasbeenrevolutionaryinourabilitytocontrolmolecular self-assembly.

TakingDNAnanotechnologyastepfurther,anavid healthcareleader,RoyFarfaraMDisutilizingDNA machinerytocreatebettermedicalsolutions.6yearsago, Dr.FarfarafoundedTrioxNanoinIsraelandbeganhismost importantendeavourofcreatingprogrammablenano machinestobetterdeliverAPIstotheirtarget.

DevelopingtheBasisforProgrammingMedicineS.M.A.R.TNanoparticlesPlatform

TrioxNanostartedin2015todevelopprogrammable biologicnanocarriersthatareabletoaccuratelydeliver payloadstotheirtarget.Thecompanydevelopedthe S.M.A.R.T(StimuliMultiAdjustedResponsive Technology)nanoparticlesplatformforintelligentdelivery ofchemotherapytocancercells.S.M.A.R.Tplatform openedawindowtoavastfieldsofinventions,of intelligentnanoscalecomputerizedmachinesthatareable tosenseacombinationofmultiplevariables(atleast2)in theirenvironmentandexertactionofunloadingactive payloadsbasedonpreprogramedmechanisms.The

disadvantagewithSMARTwasitcouldonlybe programmedatthetimetheparticlewasmanufactured.

TranscendingMedicinebyProgrammingIt

Dr.FarfarafoundedTrioxNanowithavisiontotranscend medicinebyprogrammingit.Asasurgeonintheurology department,Dr.Farfarawastreatingpatientswithkidney, bladderandprostatecancers.Hebecamewellawareofthe limitedandrelativelyprimitiveoptionsofferedtometastatic patients(surgery/chemotherapy/radiation)anddecidedto tackletheproblemfromanotherangleandtrysolveit.The company’stechnologybasedonDNAmachinerywas developedandoptimizedthroughthelast6yearsby intensiveresearchdonebyTrioxNano’sultrasmartteam thatincludesexceptDr.FarfaraproficientPostDocsfrom Harvard,Oxford,RockefellerandtheNIH.

InducingRevolutionaryandDisruptiveProgrammable Solutions

TrioxNano’stechnologicalsolutionswillinducetwo disruptiverevolutionsinthenext5-10years.Thefirst revolutionistheabilitytoprogrammedicineinrealtime, thisimprovesthetherapeuticwindowofmostmedicine.It iscurrentlybeingtestedinTrioxNano’slabonhuman cancercells.Theprogramcodesarebasedonprevious literatureknowledgeforexampleinthecaseofTNBC cancer(averyaggressivebreastcancer),literaturestatesthe abundanceofproteinslikeNucleolin,Mucin1,PDL1onthe membraneofthesecancercells.

TrioxNanousesthisknowledgeandcreatesprogramsthat areuploadedontoitsmodularparticlesothatpatientwho presentsforexamplewithMucin1inhercancerwillreceive theMuc1relatedprogram.Butoncologicliterature (accumulatedhumanknowledge)isstillverylimitedand thatisthereasonTrioxNanodevelopedthesecond technologywhichcomplementsandfurtherenhancesthe potentialofPCPMprogrammedmedicine!

Thesecondrevolutioncalled“tissuederivedprogramming” isadatarevolutionthatwillallowTrioxNanototranscend pastthecurrentknowledgegapandcomprehensively differentiatediseasedfromhealthytissues.Thisrevolution couldonlycommenceoncetheabilitytoprogrammedicine wasachieved.Tissuederivedprogrammingallowsitto uploadprogramsthatcandifferentiatetraitswhetherthey areknownorunknowntoliteratureexpressedonthetarget tissueANDnotexpressedonthehealthytissuesurrounding it.

suchasTNBCthatareknowntodatetopresent2-3 proteinscanbetargetedbythemanyyetundiscovered proteinstoday!

UtilizingDisruptive,NovelandDNAbasedTechnology

TrioxNano’stechnologyisbasedonDNAmachinery,the pandemichasproventheadvantageofRNAvaccines comparedtooldertechnologiesofattenuatedvirus.RNA vaccinespresentasmallpercentageofthepotentialoffered tohumanitybyDNAbasednanotechnology.The

Rememberingthathumanknowledgetodateislacking, TrioxNanoisjustatthetipoftheicebergasto comprehensivelydescribingalltheproteinsexpressedona specifictissuesuchasatumour.Inthecaseofacancer patient,differentmetastasishavedifferenttraitsandthe cancercellskeepdynamicallyevolvingbasedonthe treatmentsbeinggiventothepatientthroughtime.Though proteomictechnologiesallowdifferentiatingthousandsof knownproteinsatatime,itdoesaddresstreatingtheseand requiredafurtherdegreeofcomplicationtoaddressthe correcttreatmenttothediagnosedtrait.TrioxNano’s technologyallowsittochooseanduploadthecorrect sequencesoutof10^35differentsequences.

Thisrevolutionmeansthedependencyonthecurrent humanknowledge(literature)canbebypassed,andcancers

technologyissodisruptiveandnovelthattodatethereisno competition,thoughDr.Farfarabelievesthesituationwill notstaythesameandin3-5(whichisthetimeittookto createtheknowhowandexpertisetostabilizeit) competitorswillfollow

ConciseAdvicetoAspiringEntrepreneurs

Dr.Farfaraadvisestoaspiringentrepreneursto

findingtherightteam.Heconsidersthatbeing

orientedisthemostimportantvalueofabusinessleader. Hetellsthemthatfailureswillusuallyteachthemmore thensuccess,thereforepersistenceand

are required.Heasksthemtostay

totheir

beliefsnomatterwhatandiftheyhavetheoption

startby

people-

perseverance

dedicated

ideasand

choose disruptionoverincrementaltechnologicalprojects.

Fabian Ifarganm PhD CRISPR / Head of cell assays post doc Volcani

Joseph Farfara MsC Founder & CEO

Roy Farfara MD Founder & CTO Technion Yaacov Guy DsC Regulatory affairs postdoc NIH

Dorit Cohen PhD Immunology / In Vivo postdoc Rockefeller

Yoav Chemla PhD CellAssays Bar-Ilan

Michal Rasis PhD Analytics post doc BGU

Ofer Nussbaum PhD Head of chemistry postdoc NIH

Triox Nano Programmed Medicine

Toma Tomov PhD DNAprogramming postdoc Harvard

Ehud Sass PhD Head of Biology postdoc Oxford

Liroy Lugasi PhD Chemistry Bar-Ilan

Yakir Farfara Intern