The 10 Most Innovative Pharma and Life Sciences Solutions Providers 2018 January2018

Murt Abuwala Founder

Editor’s Note

Pharma Industry and IoHT

WiththeinventionoftheIOTdevices,nowadayseveryoneofusareconnectedwitheach

other'sallthetime.Themassivetechnologicalshiftofthisdimensionisfeltbyevery divisionoftheeconomyincludinghealthcare.InternetofHealthyThingsnowbridges interoperabilityhurdlestotransformradicallythewayhowhealthcareisbeingdelivered. Wearabledevicesalongsidehomehealthmonitoringsystemsarenowmoreofanecessityratherthan lifestyledevices.Whetherdatacomesfromelectrocardiogramsortemperaturemonitors,tracking healthinformationisalwaysvitalforallthepatients.Thankstotheprogressofscience,now wearabledevicescanfacilitatereal-timedatareportingwhichincludeheartrate,sleeppattern,steps taken,etc.Additionally,increasedprocessingpowerofsmartphonesalsohashelpedthesedevicesto beconnectedinabetterway Theleapsandboundsthattechnologicalprogresshastakeninthelast fewyearsshowcasesthatwhereasonceyou'dhavetogotoamedicalpractitionertogetmore informationabout.

ThankstoIoHT,itisslowlyreducingthecostofhealthcaredeliveryandhelpingthehealthcaresector totransformintoavalue-basedsystem.Accordingtovariousreports,withremotepatientmonitoring fortheheart,asthma,anddiabetespatientsaroundtheglobewillenabletotalsavingofmorethan $200bnyearly.Theworldisslowlyadaptinginterconnecteddevices,andallthesemethodswill eventuallyhelptobuildproductsthatinvolveenoughwithpatientstosupportthemincraftinghealth goalswhicharerelevanttotheirlife.

SowithgreatenthusiasmInsightsSuccesshasselectedsomeofthemostprominent organizationsaroundtheglobeintheissueof“The10MostInnovativePharmaandlife sciencesSolutionProviders2018,” Theseorganizationsaretransformingthelifescienceand pharmaceuticalsindustrywiththeirrevolutionaryinnovationsandforemostinitiativesthat mainlyfocusontheproductaccelerationandcustomersatisfaction.

ThejourneystartswithOrbytelGroup,adatascienceanddecisionsystemcompanythat exclusivelyservesthebiopharmaceuticalindustryanddriventhesuccesswithprofound solutions.

ThenwehaveOSNEXUSCorporation,whoseQuantaStorSDSisasoftware-definedstorage platformofthecompanythatturnsserversintomulti-protocol(SAN/NAS/Object)scale-out storageappliancesandexpertlyimprovestheagilityofassociateorganizations;GoldenHelix, Inc,whichprovidesoneofthebestautomationcapabilitiesthatarecrucialinhigh-throughput testingenvironments;CatalystUXisalsopartofthelist.ItdesignsandbuildsUser Experiences(UX)forMedical,PharmaceuticalandLifeScienceDigitalSolutions;thenwehave SciformixCorporationwhichisaleadingscientificknowledge-basedorganizationthat providesprocess,technologyandconsultingservicestothelifesciencesindustry;IdeagenPlc whoprovidesquality,safety,audit,performanceandriskmanagementsoftwareandexpertise andhasoperationsintheUK,theEuropeanUnion,theUnitedStates,MiddleEastandSoutheast Asia.

Also,wehaveincorporatedExclusive-AddingMobilitytoHealthcareviaEMR-HER;TechN-Trends-TrendstoBeFollowedinElectronicHealthRecordSystem;Care&Cure-The NextFrontierofInnovationinthePharmaceuticalindustry.

Lastly,don'tforgettogothroughExecutiveTalk-Top5BestPracticesthatDefinesa SuccessfulWellnessProgram;IndustryInsight-ContemporaryPredictiveAnalyticsin Healthcare;HealthPOV-HospitalLogistics–AcceleratingthePatientFlowinDanish Hospitals.

Kaustav Roy

H RM L FE SC ENCES& The

PROVIDERS 2018

Murt Abuwala Founder

Cover Story

ORBYTEL

GROUP: ORBYTEL GROUP:

Helping Organizations to Work Better and Faster

At the heart of our solutions is Harmony, our custom-built, patent-pending, cloud-based platform designed from the ground up to meet the unique needs of the biopharma industry.

Overcomingthedifferencesincultureand

communicationbetweencommercialandresearch organizationsisachallengeespeciallywhenit comestobiopharmaceuticalR&Dproductivity.Inorderto removethesebarriers,OrbytelGroup,adatascienceand decisionsystemcompany,buildssolutionsthathelpteams structure,manage,andactoncomplexdata.

ThevisionofOrbytelGroupistoempowerscientists, physicians,businessprofessionals,andpatientstoradically improvetherapeuticdevelopmentanddelivery

AVeteranLeader

Withmorethantwentyyearsofexperienceinthe pharmaceuticalindustry,MurtAbuwalafoundedOrbytel Groupin2009.Whenheinventedamathematicaland experimentalapproachtoidentifypotentialmedicinesfor neurodegenerativediseases,suchasAlzheimer’sDisease, hewasthrustintothecommercialsideoftheindustry After workinginsales,marketing,analytics,IT,managedcare, andcorporatefinancehebecameaconsultanttothe industry

Whenaskedaboutthisfutureplans,hestated“We want to make science easier for business people and business easier for scientists. This divide is at the root of the R&D productivity problem facing large companies and our aspiration is build tools that help bridge the gaps between these two very different and important groups.”

Afterleadingtwosuccessfulconsultingteamsatmajor firms,MurtstartedOrbytelGroupinordertofocusonhow organizationscanimprovedecisionmaking.Hehasworked withmorethanthirtypublicly-tradedglobal biopharmaceuticalcompanies,including7ofthetop10in M&A,portfolioanalytics,commercialstrategy,R&D strategy,salesstrategy,andmedicalstrategy

MurtisaPhiBetaKappa,magnacumlaude,andhonors graduateofOberlinCollegewithadegreeinbiochemistry. Hewaspartofthestudentgovernment,playedvarsity tennis,andreceivedawardsandgrantsfromtheNational ScienceFoundation(NSF),HowardsHughesMedical Institute(HHMI),andtheAmericanChemicalSociety (ACS)forhisresearch.

AUniqueOrganizationTakingOntheChallengesofthe Industry

AccordingtoOrbytelGrouponeofthemostsignificant challengesfacingtheindustryistheever-increasingcostof bringinganassettomarket.Thischallengeismagnifiedby

theincreasingpricingpressurebiopharmacompaniesare facing.Consequently,companiesareseekingwaysto reducecostsandfindefficiencies.OrbytelGroupbelieves thatthecoreofthischallengeispipelineassetassumption management.Assumptionsaboutclinicaldifferentiation,net pricing,reimbursement,productuptake,andpromotional responseneedtobevigorouslyreviewed,debated,and carefullymanagedtoensureR&Dinvestmentsthatare generallymadeover10yearsandareinthehundredsof millionsdollarsreflectfuturemarketrealities.

Toaddressthislargecomplexchallenge,companieshaveto organizelargevolumesofdataacrossmanydisciplines, developanalyticstandards,andstandardizedecision makingprocessesacrossthousandsofindividuals.Itisa largehigh-riskcross-functionalinitiativethatmost companiesarereluctanttoundertake.Throughitsextensive anduniqueexperienceswithmostofbig-pharmaformany years,OrbytelGrouphadauniqueperspective.Ittookthe bestpracticesfrommanycompaniesandcreateddata standardsandacommondatastructure. Followingthat, Orbytelcreatedacustomtechnologyplatformdesignedfor businessplanningandcompetitiveintelligence.Itallows end-userstointeract,visualize,andactupondata consistentlytowardsacommongoalregardlessoftheir departmentordiscipline.

HelpingOrganizationstoMakeBetterDecisions

OrbytelGrouphelpscompaniestomanage,organize,and actondatasotheycanmakebetterdecisions.The organizationmainlyworksinthreeareas-R&D/Medical Affairs,Finance,andSales.

WithinR&D/MedicalAffairs,Orbytelofferstwosolutions: MeetingAssistantandTrials.Thesemodulesarefocusedon structuringcomplexclinicalandscientificdatainawaythat iseasiertounderstand,analyze,summarize,and communicate.Theyenablecompaniestotrackandmanage muchlargervolumesofdatawhichinturnimprovestheir understandingofdatagenerationopportunitiesandrisks. ForFinance,OrbyteloffersaForecastsmoduletohelp teamscreate,manage,andcommunicatelong-termproduct valuations.ItreplacesMSExcel,standardizesforecasts acrossassets,countriesandteams,andenablesteamsto understandthelong-termfinancialimplicationsofvarious clinicaldatascenarios.Inshort,ithelpsdeterminehowto bestdirectR&Ddollars.

OrbytelGroupalsohelpscompaniesruntheirsalesforces moreprofitably ThesolutionprovidedbyOrbytel simplifiessalesoperations&analytics,optimizessales

strategyonfinancialgoals,andreducesdependencyon multiplethird-partysystemsandvendors.Through sophisticatedanalyticsandreporting,dataispresentedina waythathelpsindividualsmakebetterdecisions.Fora salesforceoffewerthan100individuals,aVPofSalesis abletoruntheentiresystemandprocesswithnoneedfor dedicatedsalesoperationsoranalyticsstaff.Thisunified, highly-streamlinedapplicationassistsenterprisesindealing withanincreasinglydifficultsellingenvironmentby loweringoperationalcomplexitiesandexpenses.

ThankstotheinnovativesolutionsprovidedbyOrbytel Group,clientsarenowabletoreducecostsandincrease efficiency.Theybelievethatbybeingabletomakebetter decisionsmoreconsistently,itsclientsalsogainbroader strategicandcompetitiveadvantages.

EnteringtheVertical MurtstartedhiscareerinpharmaR&Dasachemistnearly twentyyearsagoandhasalwaysworkedinthe pharmaceuticalindustry.OrbytelGroupwillcontinueto focusonthisindustry. Murtbelievesthebiopharma industryiscurrentlyunderpressurebutthatitwillcomeout strongerthaneverandwillhaveaprofoundimpacton healthinthenext30years.

“Thebiopharmaindustryisatthecuspofanamazing intersectionofgeneticunderstanding,biological manufacturingcapacity,andportablecomputingpower Trulyamazingthingsarehappening,andOrbytelGroupis excitedtobeapartofthegrowthandoptimisticthatitwill

havearole,howeversmall,inpositivelyimpactingpatient healthoutcomes.”

TacklingInitialRoughDaysandFuturePlans

OrbytelGroupstartedworkingontheirtechnologyin2014, butdidthingsbackwards fromthe“norm”.Ratherthan startingwiththeUX/UI, Orbytelfocusedonthedata model.Theyapproacheditas anexplorationofwhetherit couldcreateaunifieddata modelforthebiopharma industrythatcouldstructure datainameaningfulwayfor R&D,finance,and commercialsimultaneously.

Additionally,OrbytelGroup workedonadatasecurity modeltoeasilyhandlethe uniquefirewallsinthe biopharmaindustrywhile alsopermittingthesecure flowofdatabetween departmentscompliantly.This createdalow-levelblueprint forthedatastructureit wantedtoultimatelyachieve.

WhenOrbytelwashappy withitsdesign,itlookedfor anapplicationdevelopment platformtostartbuilding applicationsinwhichdata flowedseamlesslyand couldeasilyautomate workflows.Nothing readilyavailable worked,andtheymade thetough-and expensive-decisionto buildtheirown platformcalled Harmony Ittookaboutayearto createthecoreplatform andanotheryearto workoutthekinks, polishitsfeatures,and

improvetheUI. Theirnextbigchallengewascustomer acquisition.

Findingindividualswhowerewillingtolistenandlead changeviaanewandpotentiallydisruptivetechnologywas difficult.Orbytelendedup couplingitsnewsoftware productstoitsestablished servicesatstrategicaccounts. Thishelpedtoestablisha trackrecordandgradually increasetheiruserbase.

AccordingtoOrbytelGroup, startingwiththedata-model andbuildingaplatformfrom scratchwasriskybut everythingfellintoplace eventually.Oncepeople experiencedtheproduct’s benefitsandthecompany’s service,theygrewopentothe changesandmanyprovided referrals.Infact,in2017 alone,theiruserbasegrewby over300-foldandisstill growingeachmonth.

Orbytel’ssoftwareiscoupled withdataandanalytical services,training,and professionalservices-a uniquefull-serviceoffering thatitstop-tierclients demand.Orbytelisvery proudtohavea100 percentcustomer retentionrateforthe past7years.Theyplan ongrowingtheiruser basewiththeirexisting productsandexpanding theirproductofferings toadditionalareasof R&D.

“

We provide Software-as-aService (SaaS) to help our clients accelerate therapeutic development and optimize commercial success.

CompanyName

Management

CatalystUX catalystux.com

GoldenHelix,Inc goldenhelix.com

IdeagenPlc ideagen.com

PaulGiurata CEO

AndreasScherer President&CEO

DavidHornsby CEO

MethodSense methodsense.com

RussKing President

OceanDataSystems dreamreport.net RickPierro President

OrbytelGroup orbytelgroup.com

OSNEXUSCorporation osnexus.com

MurtAbuwala CEO

StevenUmbehocker Founder&CEO

PENDOPHARM pendopharm.com

Sciformix sciformix.com

SimpsonHealthcare simpsonhealthcare.com

Dr.DavidGoodman CEO

ManishVinayakSoman President&CEO

KellySimpson CEO

Brief

CatalystUXdesignsandbuildsUserExperiences(UX)for Medical,PharmaceuticalandLifeScienceDigitalSolutions.

GoldenHelixprovidesautomationcapabilitiesthatarecrucial inhigh-throughputtestingenvironments.

Ideagenprovidesquality,safety,audit,performanceandrisk managementsoftwareandexpertiseandhasoperationsinthe UK,theEuropeanUnion,theUnitedStates,MiddleEastand SoutheastAsia.

MethodSenseguidesmedicaldevice,biotechand pharmaceuticalcompanieswithquality,regulatoryand technologysolutions.Ourregulatorycomplianceconsulting enablesclientstooperatemoreeffectivelyduringthe commercializationprocessandbeyond.

DreamReport™istamingthatoceanofdata! It’sthefirst programmingfree,user-friendly,automatedreportinganddata analysissoftwaredesignedspecificallyforindustrialautomation applications.

OrbytelGroup,adatascienceanddecisionsystemcompany thatexclusivelyservesthebiopharmaceuticalindustry

OSNEXUS’QuantaStorSDSisasoftware-definedstorage platformthatturnsserversintomulti-protocol (SAN/NAS/Object)scale-outstorageappliances.

Fromallergytogastroenterologytospecialtyprescription products,PENDOPHARMspecialisesinseveraldifferent therapeuticclasses.

SciformixCorporationisaleadingscientificknowledge-based organizationthatprovidesprocess,technologyandconsulting servicestothelifesciencesindustry

SimpsonHealthcares’purposeistosupportitsclientstoshare thescientificstoryofthediseasestheytouchandthetherapies theydiscoverallinneed.

Catalyst UX:

Driven by Software, Empowered with Experience

FamedCanadianphysicianWilliamOsleronce said,“Medicineisascienceofuncertainty,andan artofprobability.”SinceOsler’stime,the medicalandpharmaceuticalindustrieshavechanged dramatically—butthatunpredictabilityremains.And whilemanymedicalandpharmaceuticalcompanieshave comeandgone—othershavemanagedtomakeamarkin thelongrunwithasustainableforward-thinking approachfocusedonunderstandingtheevolvingneeds ofproviders,patients,employeesandcustomers.

EnterCatalystUX—afullserviceuser experience(UX)firmthathelpsthe medical,lifesciences,and pharmaceuticalindustriescaterto theseshiftingdemandswith adaptive,responsive applicationandsoftware designthatmakeslifeeasier andmoreproductivefor theseusers.Backedbymore than25yearsofexperience spanning500+projects, the companyblendshuman behaviorresearchand testing,digitalstrategy,UX design,andUIdevelopmentto helpitsclientsdeliver thoughtful,consistentexperiences acrossplatformsanddevices.

ImpeccableEnd-to-End UXDesignandUI Development

services,ensuretheproperuseofmedicalinstruments andseamlesslyextendtheiruserexperiencetoalmost anymobiledevice.Thisprovenapproachmeansthe teamcanofferunrivaledspeedtomarket—delivering completedesignandcodedUIinlessthan100days.

TheInternetofThings(IoT)andotheremerging technologieshavebroughtrapidchangetotheworldof medicaldevices.Tothatend,CatalystUXhasputa strongfocusondevelopingsoftwarethatincorporates andconnectswithabroadarrayofhardwareand instruments.Cloudtechnologieshavealso openedaworldofnewopportunitiesin themedicalindustry Thecompany combinesbigdataanalytics, privacy-by-designpractices, collaborationandastrong knowledgeofregulatory requirementstohelpany organizationwiththis transition.

Catalysthasdeepexperiencewithcomplexsolutionsacross themedical,pmarmaceuticalandLifeSciencefields

CatalystUXtakesa comprehensiveapproachtoUXdesign—providingeach ofitsclientswithatwo-tosix-personteamof UX architects,UXdesigners,UIdevelopersandsocial scientists.Thoseteamsaresingularlycommittedto creatingelegantandsimplesoftwaredesignsthathelp employees,providersandpatientsaccessdataand

Astutenessof

CEO,Aiding toThrive

Thevisionarybehind CatalystUXandits sustainabledevelopmentsis CEOPaulGiurata.The ColoradonativeearnedaBAin ElectricalEngineeringfromthe UniversityofColorado,Boulder,before goingontocompletean MBAatSantaClara University.Beforefounding CatalystUX,hemadehis nameatApple,wherehetransformednumerous education-focusedresearchprojectsintocommercial solutions.Later,hemovedontoHewlettPackard MedicalProducts(Agilent),whereheplayedakeyrole inthesaleandinstallationofpatientmonitoring, cardiology,neonatalanddiagnosticimagingproductsin

We are a team of passionate UX Designers, UI Developers and Social Scientists committed to creating innovative user experiences that grow companies, create new markets and improve lives

‘‘ ‘‘

LatinAmerica,Africa,theMiddleEast,China,and Australia.

Mr.Giurataisoneoftheworld’smostexperienced solutionarchitectsandhasledthecompanywithhis provenknackfordefiningsuccessfulproductsand deliveringsimplebutelegantlydesignedsolutions.

DeliveringConsistencyinanUnpredictableWorld Paulasserts, “We guide our efforts with meaningful

observation of users, patients, scientists and caregivers to inspire solutions” Thecompanyhasfaceditsshareof challengesovertheyears,butbyusingproven methodologies,committingtocollaborationandbuilding teamsthataretrulypassionateabouttheworktheyare doing,he’sturnedthesesetbacksintoopportunities. Today,thecompanydeliversthelatesttechnologiesand optimizeduserexperiencestopromisingindustryupand-comers,andfurtheraimstobuildonsuch collaborations.CatalystUXhelpspharmaceuticaland medicalcompanies improvepatient outcomes, accelerate discoveriesand makeameaningful impactonmankind. Goingforward, Giurata’sgoalisto collaboratewith globalleaders—as wellasemerging innovators—to deliverempowering medical,lifescience pharmaceutical solutions.

Paul Giurata CEO

Paul Giurata working with his Team

Golden Helix:

Helping Researchers and Clinicians Understand the Role of CNVs in Human Health and Disease

Foundedin1998,GoldenHelixisaglobal bioinformaticsfirm.Sincefoundation,the organizationhasaccumulatedasignificantcustomer baseandiscurrentlyworkingwithmorethan350 organizations—withthousandsofusersleveragingthe organizations’variousanalyticsproducts.Fromitsearly daystillthepresent-day,GlaxoSmithKlinehasbeenthe largestoutsideinvestorofGoldenHelix.Tilldatethe organizations’softwarehasbeenreferencedinmorethan 1000publications.ThecustomersofGoldenHelixfallinto fiveprimarycategories:testinglabs,hospitals, pharmaceuticalcompanies,majorresearchorganizations andgovernmentorganizations.

AWell-knownLeader

Backin2013withtheobjectiveofleadingthebusinessinto genetictestingmarket,AndreasSchererjoinedGolden HelixasthePresidentandCEO.Whileworkingfor organizationslikeNetscapeandAOLasaGlobalVice President,Andreasgainedmuchneededvaluableinsightsin runningworld-widebusinesseswhichrequirefunctional know-howinsales,marketing,productdevelopment, servicesandoperations.

HiseducationalbackgroundiscenteredaroundComputer ScienceinwhichheholdsaPhDfromtheUniversityof Hagen,Germany Andreashassofarpublishedmorethan twentypeerreviewedarticles,authoredbooksonNeural Networks,IntranetsandProjectManagement.Hislatest book, “Be Fast Or Be Gone” wasaprizewinnerin2012 EricHofferAwardscompetition.

Inhisprivatetime,Andreasenjoysweightliftingthroughout theyear.Inthewinters,helikestospendtimeskiingthe mountainsofMontanaandinthesummer,youcanfindhim onthegolfcourse.

EmpoweringEndUserstoPerformHigh-EndAnalytics Work

GoldenHelix’smaingoalistoempowertheirendusersto performhighendanalyticswork.Thisisachievedby

producingsoftwarewhichgivesthepowerofanalysisto researchers,supportingthemthroughtheiranalysis,andby providingthemwithgenomicserviceswhentheneed arises.

GoldenHelixtakesprideinitselfforcreatingsoftwaretools thatareintegratedandrobust,butmoreimportantlyuserfriendlyandintuitive.Thetoolsarespecificallycreatedin ordertoempowerbiologists,cliniciansandother researcherstoeasilyperformcomplexanalysesand visualizations,eliminatingtheneedtorelyexclusivelyon bioinformaticexpertsorcobbletogetherdifficulttouse, incompatiblefreeware.Thiswayresearcherscan completelyfocusontheirresearchinsteadoflearningtobe aprogrammerorwaitinginlineforbioinformaticians.

Theorganizations’supportteamismotivatedbyone mission—tomakesurethatthecustomershaveagreat experiencewiththeirsoftwaretools.Fromhelpingto importdata,bugdetection,andfindingtechnicalresources, GoldenHelixisfullycommittedtoprovidingitscustomers withtheresourcestheyneedinordertocompletetheir analysisinaworld-classmanneratalightningfastpace.

Theorganizationdoesn’tjuststopatsupport,italsooffers comprehensiveandpersonalizedtrainingsessionstohelp researchersjumpstarttheirresearch.GoldenHelix’sField ApplicationScientistsandEngineershelpresearchersby takingthemthroughworkflowsthatarerelevanttotheir specificresearch.

GroundBreakingProducts

GoldenHelixhasdevelopedapowerfultechnologystack thatsupportsanumberofproductsinthegenomicsspace, includingthefollowing:

Ÿ

VarSeq: VarSeqisanintuitive,integratedsoftware solutionfortertiaryanalysis.WithVarSeqyoucan automateyourworkflowsandanalyzevariantsforgene panels,exomesandwholegenomes.

Ÿ VS-CNV: DirectlycallsCNVsintargetregionsand

Ÿ

Ÿ

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avoidsthecostandturn-aroundtimeofadditionalCMA orMLPAtesting.

VSPipeline: Repeatableclinicalworkflowsessentialfor CLIAandCAPcertifiedanalysis,creationofhigh throughputpipelinesandaccesstocuratedannotation sourcesthatareupdatedregularly

Ÿ VSReports:WithVSReports,youcaneasilyconvertthe outputofyourtertiaryanalysisintoacustomized clinicalreport.Afteryou’vefiltereddownyourimported variants,simplyselectvariantstoincludeinthereport.

Ÿ

VSWarehouse: Ascalable,multi-projectwarehousefor NGSvariantcallsets,clinicalreportsandcatalogsof variantassessments.

attractiveforcertainmarketsegments.GoldenHelix’s futuredevelopmentplansincludeastrategytodeploy theGoldenHelixstackinawaythatcustomerscanpick andchoosetheirpreferreddeploymentmodel:

Ÿ

OnPremises:Currently,themaindeploymentmodefor GoldenHelix.Thiscontinuestobeahighlydesirable approachashospitalsandtestinglabsareconcerned abouthostingpatientdataoutsidetheirpremises.

Ÿ

Cloud:Certainsegmentsofthemarkethaveaccepted cloudsolutionsasviable.Thecompanyisextendingout technologystackinthisdirection.

Ÿ

SNP & Variation Suite (SVS): SNP&VariationSuiteis apowerfulanalytictoolcreatedspecificallytoempower biologistsandotherresearcherstoeasilyperform complexanalysesandvisualizationsongenomicand phenotypicdata.

Ÿ MixDeployment:Forcertaindeploymentscenarios,a mixedapproachispreferable.Forexample,incertain scenariositcouldmakesensetoruntheanalysisand clinicalreportspipelineonpremisesandstoreallthe resultingdatainacloudhosteddatawarehouse.

Ÿ

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GenomeBrowse: Apowerfultoolthatdeliversstunning visualizationsofyourgenomicdatathatgivesyouthe powertoseewhatisoccurringateachbasepairinyour samples.

ADifferentOrganization

Whenitcomestoclienthandlingandprovidingsupport, GoldenHelixisacompletelydifferentorganizationfromits competitorsmainlydueto:

Ÿ Pervasiveness:Thecompanyhasastrongcompetence buildingon-premisessolutionsforthelifesciencespace. Todate,manylabs,hospitalsandgovernment organizationsprefertocontroltheITenvironmentover cloudsolutions.However,astheclinicaltestingspace goesmainstream,clouddeploymentmodelsare

Ÿ

Internationalization:TheUShasbeenastrongmarket forclinicaltestingandresearchanalyticsproductsand services.However,selectedmarketsinEurope,Asiaand LatinAmerica,aswellasAustraliaandtheMiddleEast areincreasinglyimportant.GoldenHelix’smid-term strategyistoincreaseitslocalpresenceinthesemarkets eitherthroughpartnersordirectly.

Preservation:GoldenHelixhasastrongcustomerbase withahighrenewalrate.Itshighrateofcustomer satisfactionandthestickinessofitssolutionisoneof thereasonswhyGoldenHelixhasbeenhighlycapital efficient.Theorganizationcontinuestofocusonahighqualitycustomerexperiencetoencouragefuture renewals.

Andreas Scherer President & CEO

We provide a complete end-to-end solution for clinical labs and hospitals to analyze Next-Generation Sequencing data

‘‘

Trends To Be Followed In Electronic Health Record System

MedicalScienceissomethingwhichisgrowingat averyfastpace.Fornotingdownthediagnosis, thedoctornomorerequiresapenandpaper Eventhewords“ElectronicHealthRecords”arenotnewto thetoday’sworld,buttheupcomingtrendsofElectronic HealthRecords(EHR)orElectronicMedicalRecords (EMR)areinteresting.

Eventhemedicaltrendslikegamification,wearable, telemedicine,mobilemedicineand3Dprintingarenowold concepts,buttheirmodificationsaresomeoftheamazing thingtowitness.Sciencewillneverreachitspeakasthe sky'sthelimitandnothingcanstopit.3Dprintinghas changedthemedicaltechnologytoanextremelevelby creatingcustomprosthetic,surgicalimplantsandbioprintedtissue.Expertssaythattheworldissoongoingto see3Dprinteddrugstoo.

Whileonediscussesaboutthemostemergingtrendsin EMR-EHR,thepersoncannotmisstalkingaboutthe following: Everythingisinthecloud Withthecloudtechnology,keepingmedicalrecordsare muchcheaperandeasiertoaccess.Aspertechnologists, nothingismoreportablethancloudasitonlyrequiresa computerorasmartphonewithinternetconnectioninit. Researchhasinformedthattheon-premiseEHRcancost about$40,000tosetup,butthecloud-basedEHR infrastructureandmaintenancecostsincludeitsmonthly chargesjustmissingthehighstartupcosts,arestilllesser thanthein-houseEHR.

Thecommonbenefitsofcloud-basedEHRincludethe securityfactors,privacy,costeffectiveness,accessibility,

reducedItrequirements,bettercontinuityofcare,easier updatesandimprovementstosoftwareandthemost amazingpluspointisthatitiscustomizableaccordingto choices.

Providingpatientportals

Anothermostgrowingtrendisthepatientportals.Itis somethingwhichhelpsthemedicalpractitionersin increasingthequalityofthepatientcareandinreducing medicalerrors.Whileagroupofpeoplewaseducatingthe patientsabouttheprocedureofusingtheportal,they informedthatthepeopleareinterestedinusingamedical portaltoengagethemselvesdirectlytothephysicians.This helpsthemtotracktheirmedicalhistory,receiveeducation materials,medicaladvicesandpatientsupport.

Theportalsprovidesomeinterestingfeaturessuchas prayersforpatients,directaccesstotheirmedicalrecords, personalizedhealthremindersandtotalhealthprograms suchaspersonalizeddietcharts,exerciselists,and medicinalguidance.

Telemedicineisthenewmedicaltool

Thedictionarydefinestelemedicineastheremotediagnosis andtreatmentofpatientsbyusingtelecommunications technology.Expertsclearlymentionedthebenefitsofthis newmedicaltoollikethatwiththisthemedical practitionerscaneasilygivecaretoremoteandhomebound patientsinamuch-reducedcostofcarewhileeliminating theriskfactorsofpickingupnewillnessesinaclinicalcare settingandprovidingmoreflexibilitytoproviders.

Reportssuggestedthatthenewlymedicinaltooliscurrently helpingrecoveringstrokepatientsinmanyruralareasofthe UnitedStatesofAmerica.Theadoptionofwearableis

helpingdoctorstoprovidebetterpatientscarethrough telemedicine.AndTransparencyMarketResearchhas estimatedthatthevaluationofglobalvideotelemedicine marketwouldriseto$1,624.4millionbytheendof2020.

Buildingtrustontheinfluxofdataisthemost importantfactor

Thereisnothingmoreimportantinoptimizinginoperation throughEHRthanbuildingthetrustonthedatathatis beingcapturedasthereisalwaysamajorconnection betweentrust,data,andvalue-basedhealthcare.Experts suggestthatnothingcanbeanidealopportunitythan buildingabridgebetweenthehealthcareprovidersand technologycompanies.Themostimportantpartisfilling thegapwithtrustbetweentheinsurancepartnersaswithout thatthestakeholderswouldnotbewillingtomakedata accessibleforone'spracticethatwillultimatelyleadto variousissues.

Securityremainsthemainconcern

Theworldisdevelopingatarapidspeed,andsoisthe medicaltechnology.Withtechnologicaladvancements, EHRisimprovingitself,butthesecurityconcernsare

increasingtoo.Aspersomeoldreports,adatabreachcosts anorganizationofanaveragetotalof$3.8billion.Itwas reportedthatthe49percentbreachesintheU.Sarethe resultofcriminalattackratherthanhumanerrororasystem glitch.Expertscommentedthatcyber-attacksmightcome fromoutsideanorganization,buttheexecutivesofthe hospitalitselfareconcernedaboutthesecurity vulnerabilitiescreatedbytheemployees.Asreportedby FierceHealthcare,“Nearly60percentofbreachesinthe monthofFebruaryweretheresultofinsiderthreats. AccordingtothemostrecentProtenusBreachBarometer Report,44percentofincidentsinMarchweretriggeredby insiders.”

EHRisnomoreunknowntothepeople,butthe modificationswithinthatare.It’simprovingliving conditionsandbetterhealthcarefacilities.Investorsmight finditinterestingthatthissectorisagrowingsectorand newchangesarealwaysaccepted.Bythesametime,itis alsoimportanttonotethatthoughallthesetrendsare growing,itstillrequirestoomuchattentionandmassive developmentalinvestments.

Ideagen:

The Undisputed Leader in the Governance, Risk and Compliance (GRC) Marketplace

Launchedin1993,IdeagenisaUKbasedpublic companythatprovidesquality,safety,audit, performanceandriskmanagementsoftwareand expertise.HavingoperationsintheUK,theEuropean Union,theUnitedStates,MiddleEastandSoutheastAsia, thecompanyalsoboastsaglobalnetworkofpartners servicingAsiaPacific,EuropeandSouthAmerica.

Ideagenhasacustomerbaseofmorethan3,000 organizationsusingitssuiteofproducts,includingmany blue-chipnamessuchasBAESystems,Ryanair,Heineken andtheEuropeanCentralBank.Ideagenalsocountsover 150hospitalsintheUK,USandbeyondaspartofitsclient base.Ideagenhasgrownbothorganicallyandthrougha numberofstrategicacquisitions,andthisyearrecordedits th8 consecutiveyearofgrowthinrevenue,adjusted EBITDAandadjustedearningspershare.

ADedicatedandAmbitiousLeader

IdeagenCEO,DavidHornsby,isaScottish-born, Yorkshire-raisedbusinessman.HeattendedLeeds GrammarSchoolandthenSedberghBoardingSchoolin Cumbriabeforeattendinguniversity.Hestartedhis professionalcareerasaSalesman,beforeforgingapath throughthesalesranksofseveralcomputersoftware companies.In2009hewasintroducedbyhisbroker, FinnCap,tosoftwarefirmDatumInternational,aprecursor ofthecurrentIdeagen.Havinginvested£250,000into Datum,therefollowedseveralacquisitionsandthe modern-dayIdeagenwasborn.

TheUndisputedLeaderoftheIndustry

Ideagen’ssoftware,particularlyitscloudbasedproduct Coruson,isleadingtheindustryintermsofmodernGRC systems.Itisanenterprisecloudsoftwarethatprovides completecontrol,visibility,andreal-timereportingof

everydetailandaspectofsafetyandoperationalriskinan organization.Theproductisafavoriteamongstclientsasit isscalable,extremelyuser-friendlyandfunctionallyrich. Indeed,itwasCoruson’s userfriendlinessthatwasamajor factorintheproductbeingchosenbytheInternational AirlinesGroup(IAG)–ownersofBritishAirways,Iberia, VuelingandAerLingus–RyanairandJaguarLandRover tonameafew.TheproductalsoreceivedtheGRC20/20’s EnvironmentalHealth&SafetyTechnicalInnovation awardforitsuserexperience,analyticsandmobile capability

AnotheruniqueareaofIdeagenisthelevelofexpertise withinthefirm’s400-strongworkforce.Thisisahuge sellingpointfororganizationslookingtodobusinesswith Ideagen.Lookingatquality,safety,auditandrisk management,Ideagenhasindustryexpertswithdecadesof experienceineachoftheseareas.Indeed,someof Ideagen’sstaffinvolvedintheinternal,operationaland financialauditareashavebeenpraisedbyclientsduringthe procurementstageasbeingsomeofthemost knowledgeableexpertstheyhaveworkedwith.

EquippingClientswithWorldClassTools,Services, andExpertise

Highlyregulatedorganizationsrequirethetools,services, andexpertisethatIdeagenprovidestohelpthemidentify, assessandmanagecorporateriskwhilecomplyingwith internationalindustrystandards.Manyofthese organizationsareonlyintheearlystagesofadoptingan enterprise-wideapproach.Ideagen’ssoftwaretoolsenable organizationstoidentify,assessandprioritizeriskand manageinformationinlinewithrigorousregulations.In eachofthechosenverticals,Ideagen’scustomersare increasinglyrequiredtotakeaholisticviewofrisk management,internalauditandcompliance,withmany organizationsatthebeginningoftheadoptionphaseof highvalueenterprise-widesolutions.Inshort,itssoftware

solutionsenablethemtocomplywithregulationsthat allowthemtooperate.

Ideagenseesitscloudsolutionsasaparticularareaof growthwhichwillincreasethepercentageoftotalrevenues derivedfromrecurringcontracts.

WhythePharmaandLifeScienceVerticalwasa NaturalMove

Alignmentwithhighlyregulatedverticalindustrieswasa naturalmoveforIdeagen.Thepharmaandlifescience verticalisstillahighlyregulatedone,andthesoftware, services,andexpertiseofIdeagenisanaturalfitfor organizationsthatoperatethere.Itisavolatileandever changingregulatoryenvironment,butIdeagen’sproducts helptheseorganizationsdemonstratehighlevelsofquality andcompliancewithanumberofinternationalstandards andregulationssuchasISO,theFDA(including21CFR Part11),USDepartmentofAgriculture(USDA)and MHRA.

Morethan200LifeScienceorganizationsworldwide includingReckittBenckiser,ReadingScientificServices (RSSL)andRoslinCells,relyonIdeagentohelpthem improvethemanagementoftheircomplianceprocesses andinformation,increaseoverallbusinessefficiencyand maintaindataintegritytotransformthemanagementof complianceactivitiesfromacostlyoverheadintoa businessbenefit.

FutureRoadMap

Inordertodrivegrowth,Ideagenhassuccessfullyadded newcustomerstotheGroupacrossallofitskeyGRC verticals,withaviation,lifesciencesandfinancialservices providingparticularnotablesuccessintheyear The organizationwillalsocontinuetomaintainafocuson productenhancementandinnovation,whichhasseen acceptanceacrosstheuserbase,resultinginsignificant revenuesfromstrongretentionofrecurringcontractsand newprojectsfromitsextensivecustomerbase.

Furthermore,Ideagenremainscommittedtoitsongoing buyandbuildstrategyandwouldexpecttocomplete furtheracquisitionsinthefutureassumingtargetsmeetits criteriaandrepresentvalueforshareholders.

Tofacilitatethegrowthofrecentyears,Ideagenwill continuetoinvestinitsemployees,productsand infrastructure.Significantresourceswillalsobeinvestedin benchmarkingprocessesandsystemstoensurebest practiceisstandardandthatIdeagenremainsfitforgrowth. Ideagenremainscommittedtotherelevantaccreditations, andcurrentlyholdsMicrosoftGoldPartnerstatus,ISO 9001,ISO27001,andISO14001.

David Hornsby CEO

With an excellent portfolio of software products, Ideagen helps the world's leading brands to improve operational efficiency, strengthen compliance and oversight and anticipate and manage every detail of risk. This enables organizations to reduce costs and improve efficiency

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Top5BestPracticesthatDenes aSuccessfulWellnessProgram

Overrecentyears,morecompanies areincorporatingwellness initiativesintotheiroffice environment.It’smissioncriticalintodays competitivemarkets,toattractingandretain thebesttalents.Onecrucialmeasurementis theengagementlevelsofeveryoneinthe entireorganisation.Presenteeismisatanall timehigh.Peoplearenotmotivatedby moneyalone,andwellnessprogramsarepart ofthestrategytoimprovejobsatisfaction andproductivity.However,onlyafew companiesactuallyhavecomprehensive programsthatproducebetterhealth outcomesamongemployees.Asaresult, improvedengagementandperformanceat work,naturallyfollowssinceemployeesare healthierandhappier.

Unfortunatelynotallhealthandwellness programsaresuccessful.Thefirstoneortwo initiativesmaygaintraction,buttwoyears on,andtheparticipationratesdecline.One mainproblemisthattheparticipants themselvesaren’tpartofthecreation.Their needsandconcernsaren’taddressedso there’slessmotivationforthemtocommit. Sowhatdoemployeeswant?Hereare5best practicesthathelpcreatesuccessful corporatewellbeingprogramsthatgaintrue engagement.

1.ProgramsAreDoable,Accessibleand Sustainable

Imagineawellnesstalkorfitnessclassis

AbouttheAuthor

Dr. Gary Tho is the owner of Chiropractic Works, a Family Sports and Wellness clinic in Orchard Road, Singapore. He specialises in pain relief and preventative care and believes quality life is essential for happiness, success and peak performance. Dr Gary is also the author of The Pain-Free Desk Warrior, Free yourself from aches and pains which is the definitive guide for those stuck at their desk for more than 2 hours a day.

startingin15minutes.Many employeeseasilydismissitandthink “I’dlovetogo,butIreallyneedtoget thisworkdone.”Doprogramsrun whenemployeesaremostbusy?Are runafterofficehours?Andifso,will peoplestaybackforit?Isthewellness programabroad-basedandholistic approach?Orisitjustyogaclasses, cookingdemonstrationsandnothing else?

Isiteasyforparticipantstolearn? Whatlookseasywhenatrainedchef preparesahealthydinnerin20minutes couldtaketheaveragepersonalot moretime,energyandstress.Aresteps providedforonetoimplementthenew habit,accomplishtheirgoalandsustain thesuccess?

Acomprehensivewellnessinitiative needstoofferavarietyofscheduled programsthatarebrokendowninto achievable,sustainablehabitsthat createavaluableoutcome.Equally importantisthatemployeescanchoose whattheyareinterestedin,andeasily fitintotheirschedule.

2.TheWorkEnvironmentIsHealthConscious

It’snousehavinghealthandwellness programsifthephysicaland psychosocialenvironmentwithinthe officedoes’tsupporttohealthyhabits. Greatofficedesignthatsupport wellbeinghasbeenthetrend,since FacebookandGoogleshowedushow todoit.

Creatingcreativespacesforsmaller podmeetings,havingstandingdesks andensuringthecafeteriaandvending machinesaroundtheofficeoffer healthierfoodchoicesthatcanbe easilyseenaresomeofthesimple waystoencouragegoodhealth. Ensuringregulatednoise,inspiring music,goodairqualityand temperatureandadequatelightingare alsosimpleyetimpactfulfeaturesofa greatofficespace.

Allowing‘down’times,andwork breaksthatareencouraged,isessential. Mostpeopledon’ttakebreaksorchit-

chatbecauseofitsnegativeperception. Howeverthisisabsolutelynecessary asitcreaterealinteractionandreal friendshipsbetweenco-workersthat satisfythebasichumanneedforsocial connections.Peopleneedotherpeople tolove,trustandsupportthem,inboth businesstasksaswellasatapersonal level.

3.

WellnessIsIntegratedIntoThe Company’sStructure

Furthertopoint2above,choosinga healthierlifestyleanddoingwellat workshouldn’tfeellikeatug-of-war I’veheardofcompanieswhopayfor gymmembershipsfortheirstaff,which isgreat.However,whenanemployee isworkingoutinthegym,theygeta phonecallsayingtheyneedtogetback intheofficebecauseof…(some reason).Thereforeit’simportantthata companyestablisheswellness programsthatarevaluedandhonored ineveryaspectoftheorganization. Otherwise,what’sthepoint?Another exampleincludestheholygrailof “work-lifebalance”.Ifyourcompany wantsemployeestobehealthyand havebetterwork-lifeintegration,yetat thesametimesilentlyimposesthat peoplemustcontinueworkingbeyond standardofficehours,itreallydoesnot makeanysense.One(partial)solution tothisisintroducingflexi-hoursas wellasremoteworkingtoallowpeople togeterrandsandfamilyengagements done,aswellasworkfromhome,ora cafeinsteadofbeingphysicallyinthe office.It’sapartialsolutionbecause givingsomeonetheabilitytorun errandsandcometoworklaterthan usualisgreat,thoughitdoesnot necessarilypromotehealth,happiness orwellbeing.

4.WellnessIsLinkedToContinued SupportPrograms

Whenacompanyisgenuinely concernedabouttheiremployees’ wellbeing,theywillnaturallyensure thatanywellnessinitiative,gameor workshophassomeformof continuation.Employeeassistance programs(EAP)arecommonfor mentalhealthconcerns,howeverthere needstobeothersupportsystemsin

placeforotherhealthconcerns.In 2014,Apple’sCupertino,Calif.-based headquartersboastedamedicalonestop-shop“wellnesscenter”offering in-housechiropracticcare,dieticians andmore.CollectiveWorks, Singapore,thelargestpremiumcoworkingspaceinAsia,nowalso housesanin-housechiropractor, specializinginpainrelief,peak performanceforbothindividualand corporatehealth.

Gamificationofcorporatehealth programsusuallyrunforacertain periodoftime.Workshopsandclasses mayrunfor8weeksorthroughoutthe entireyear Althoughparticipation ratesarehighinitially,continued supportprogramsarewhatsustains engagement,andcreatesthechange bothindividualsandtheCEO’swantto see.Engagementiswhatcreateslong termsustainableresults.

5.Broad-basedApproach WellnessProgramsaren’tallabout offeringfreegymmembershiporjust havingsmokingcessationprograms. Healthishealth-acompletestateof physical,mental,andsocialwellbeing.Fitnessis“theabilitytoperform work(sports,occupationsanddaily activities)satisfactorily”.Pilatesisa greatwaytoexerciseandstrengthen thecoremuscles,howeveritisnot equivalenttohealth.

Alotofpeopleknowtheyshouldquit smokingbutdoesn’tbecausethey don’trealizehowmuchdamageitcan dototheirbody.Theymaynothavea strategy,norenoughmotivationto makethosechanges.Onemethodof offeringvoluntaryhealthscreenings whilegivingsoundeducationand simpletasksfromavarietyof professionalsisthekey.Helping peoplerealisethatthecompanydoes care,thattheircolleaguesdocare,that theytooshouldcareabouttheirown healthisofthegreatestimportance. Diggingdeep,andcreatingasafeplace toimprovetheirlifestylechoiceson multiplelevelsshouldbethebasisof everycorporatewellbeinginitiative.

OSNEXUS:

A Leading Hyper-Scale Software Defined Storage Provider for Life Sciences

Theinternethasbecomeamassiverepositoryof information,animportantadvertisingmedium,and theidealcloudstoragemanagementservicefor almosteveryindustry.Fromsmallstartupstomultinational companies,organizationsarestoringmassiveamountsof enterprisedataandinformationrelevanttotheiroperations onwebsites.Theyallrequireanefficientandscalable storageplatformtomaintainandorganizethisinformation. LifeSciencesorganizationstodayarestrugglingtokeepup withmassivedatagrowthduetoadvancingtechnologies, andsectorslikeGenomicsareproducingupto40exabytes ofdataperyear.

Thecurrentmarketiscrowdedwithstorageproviders,most ofwhichofferatraditionalmodelknownasthe’multitude ofsilos’construction.However,organizationsfindit difficulttoorganizetheirdatausingthattraditionalmodel;a uniqueandadaptablesolutionisbecomingincreasingly essential.

AnewdatastoragemodelcalledSoftwareDefinedStorage cameintoplaytosolvesomeoftheproblemsassociated withlegacystoragesystemssuchashighpricesfor softwareandhardwarecombinationsandvendorlock-ins. WithSoftwareDefinedStorage,companiescanbuy commodityhardwareandinstallseparatesoftwareto managetheirdata;amoreeconomicalapproachthan traditionalstoragesystems.

OSNEXUSCorporation(OSNEXUS)standsoutasa SoftwareDefinedStoragecompanywithitsstoragegrid technologythatisbuiltintoitsQuantaStorSDSplatform, whichsimplifiesstoragemanagementbyallowingalldata tobemanagedfroma’single-pane-of-glass’webinterface whichrequiresnoadditionalsoftwaretoinstall;aleapin progressforopenstorageplatforms.

QuantaStorSDSenablesorganizationstousestandard serverhardwareastheirstorageappliancesbutOSNEXUS hasgonefurthertoprovidereferenceconfigurationsand certificationswitheverymajorservermanufactureronthe marketwhichprovidesleverageandchoiceinhardware purchasedecisionsforLifeSciencesorganizations.

Theuseofmultiplegenerationsofserversandtheuseof serversfromdifferentmanufacturersisfullysupportedby

theQuantaStorSDSplatform,whichenablesorganizations togrowtheirstoragegrid(s)ondemand,atthebestprice, andwithouttheprocurementdelaysandhighcapital expendituresoftraditionalproprietarySAN/NASsolutions.

QuantaStorSDSscalestoover60PBpergridwhichis essentialtoaddressingthedatagrowthanddatasecurity challengessurroundingLifeSciencesandatanaverage savingsof50%ormoreversustraditionalsolutions, QuantaStorenablesorganizationstocollectmoredataand retainitlongersothatdeepanalyticscanbedoneinactive andfutureresearch.

InsightfulInnovation

StevenUmbehocker,FounderandCEOofOSNEXUS bringsovertwentyyearsofexperienceintheenterprise storagesoftwareindustrytothechallengesofhyper-scale storagemanagement. Hecurrentlyholdsover20patentsin StorageSystemsTechnology,SDS,andCloudComputing, andhaspreviouslyledengineeringteamsatsomeofthe world’slargestITcompanies,includingCitrixSystems, Symantec,andVeritasSoftware.

In2009,Stevenwasleadingthedevelopmentofnew enterprisestoragemanagementtechnologiesforXenServer andsawtheneedforanewkindofstoragesystemthat wouldscaleasagridacrosssitesanddatacentersinorderto eliminatethecomplexityandscalabilityissuesinherentto traditionalstoragesystems.Theresultofthatvisionwasthe foundingofOpenStorageNexus(OSNEXUS)in2010and thecreationofQuantaStorSDSwithateamofstorage veteransfromVeritasandCitrix.

AUnifiedDataStore

QuantaStorSDSisOSNEXUS’flagshipproductandoffers file,block,andobjectstorageinasinglesystem.Besides QuantaStor,OSNEXUSprovidesprimaryproduct-specific services,includingVirtualStorageAppliances(VSAs) availableintheMicrosoftAzurecloud.VSAsare virtualizedinstancesofQuantaStorSDSwhichmaybe addedtostoragegridsmadeupofbothphysicalandother virtualappliances.

OSNEXUSalsoofferstheQuantaStorSDSCloudLicense Service,whichgivescustomerstheconvenienceofselfprovisioninglicensekeys.ITprofessionalsfromtheLife

Unify, Simplify, and Automate your data with QuantaStor SDS

‘‘ ‘‘

Sciencessectorfindthissolutionespeciallyusefulbecause itenablestheirITorganizationstoquicklyscale,deploy, andredeployappliancestoamultitudeofresearchprojects withease.

DistinctiveFeatures

QuantaStorSDSisanall-in-onesolutionthatmeetsthe needsofavarietyofdifferentindustriesandusecase scenariosincludingservervirtualization,bigdata,cloud computing,andhigh-performanceapplicationsthrough scale-outphysicalandvirtualstorageappliances

Dataisprotectedusingend-to-endencryption,which combinesdata-at-restencryptionwhichisAES-NI acceleratedcombinedwithprotocol-level/on-the-wire encryptionwithSMB,IPsec,andHTTPSacrossany storagegrid

QuantaStorprovidesPharmaceuticalandLifeSciences organizationsthedatatransferspeednecessaryfor accessing,collaboratingon,andmanagingmassiveamounts ofstructuredandunstructuredscientificdata,backupand migrationstrategies,objectstorage,genome-basedfile access,encryption,andcompliance.

OSNEXUSfeatureslikehardwareandsoftwarediskdrive encryptionwithIntelAES-NItechnologyandadvanced usersecuritywithrole-basedaccesscontrolsareunmatched inthemarket.QuantaStorSDSisprotectedagainstsystem failurethroughreplication,andincorporatesexpedited disasterrecoverymechanismslikedatasnapshots.

TheFutureofStorage

Manycompaniesusepubliccloudstostoretheirdata, whichseemlikealow-costoptionfordatastorage.In industrieslikeLifeSciences,however,whenpetabytes(one milliongigabytes)ofdataareproduced,publiccloudsare

noteconomical.Asanexample,AmazonWebServices charges$0.03/GBpermonth,whichis$0.36/GBperyear whichequatesto$360/TBperyear.Atthescaleofone petabytethatamountsto$360,000/yearor$1.8millonover 5years.

Incontrast,adedicatedQuantaStorsolutionincluding hardware,software,andcloud-hostingwouldsaveasmuch as75%ormoreversusAWSS3orothercloudobject storageservices.That’sbeforetransfercostsarefactoredin, andwhenoneaccountsfortheneedforresearcherstorun advancedanalyticsapplicationsagainstthedata-the savingscaneasilycometoover90%versusAWS.

LookingAhead

OSNEXUShasgrownorganicallyataterrificpacesinceits inceptionin2010.Initsearlydays,thecompanyfocusedon developingitsinnovativeQuantaStorSDS,engineeringand creatinganunbeatableopenstorageplatform.Today, OSNEXUScontinuestoexpandthecapabilitiesof QuantaStorSDSatanevenfasterpacewithnew innovationsinsecurity,datareplication,andapplication integration.Inthecomingyears,QuantaStorwillalso includedataintegrationfeaturesintotheSDSgrid architecture,whichwillimproveusers’decision-making abilitybyreducingthecomplexityofinformationavailable. QuantaStorSDSuserswillbeabletoutilizevisualtools likegraphs,charts,anddashboardstobetterunderstand theirstorage,andsimplifycapacityplanningaccordingly

QuantaStorSDSisavailableworldwidefromanetworkof partnerresellersanddistributorsandOSNEXUShasbeen helpingindustrygiantslikeIBM,Cisco,CenturyLink,Intel, andMicrosoftbringSDSinnovationstotheircustomers. Thecompanyaimstosustainandbuilduponthesestrong partnershipstoexpandtheirworld-class,practicalopen storagetechnology

Steven Umbehocker Founder &

CEO

HOSPITAL LOGISTICS: ACCELERATING THE PATIENT FLOW IN DANISH HOSPITALS

Formorethanadecadehospitalproductivityhasbeenapriorityin Denmark.Afocusonqualityandqualityimprovementshasreduced therateofre-admittancetoDanishhospitalsandademandfrom centralauthoritiesonhospitalstoincreasetheirproductivityby2%every year,hasduringrecentyearsresultedinalotofnewinitiativesand innovations.Withare-organizationoftheDanishhospitalstructure,thishas ledtoatotalproductivityincreaseof30%since2003.

The concept of Hospital Logistics and Solutions to improve logistics and create just-in-time scenarios in hospitals is another factor behind the productivity increase which is further explained in this article.

Healthcaresystemsaroundtheworldarechallengedbyanincreasedshareof elderlycitizensandchronicallyillpatientsaswellasmoreexpensiveformsof treatment.

Thesefactorsarecausingasignificantdemandpullintermsoftreatment needsaswellasexpectations,whichaccentuatetheneedforourhealthcare systemstoworksmarteronalllevels.Therefore,hospitalsneedtoconsider meanstoincreaseefficiencyandproductivityinordertobeabletotreatmore patientswithoutincreasingcosts.

Formorethanadecade,Danishhospitals andcompanieshaveworkedtogetheron improvinglogisticsinhospitals.Theoverall aimhasbeenthecreationofjust-in-time solutionsinordertooptimizecoordination andefficiencyandreducethepatients’ lengthofstay

InDenmark,thefocusonhospitallogistics hasplayedanimportantroleinachievinga 30pct.increaseinhospitalproductivity since2003.Optimizinghospitallogistics withindifferentareasofhospitalservices andneeds,includingsupplylogistics, clinicallogistics,sterilegoodsandsample logisticscanacceleratethepatientflowand leadtoincreasinghospitalproductivity

‘Just-in-time’logistics

Innovativehospitallogisticssolutionsare alreadyimplementedinDanishhospitalsin

ordertoreducedelaysandwaitingin ordertospeedupthepatientflow

AttheNewAarhusUniversity Hospital,afine-meshedITsystemwill enablereal-timelocalizationofpeople andequipmentrightdowntoroom level.

AtAalborgUniversityHospital,the introductionofasimilarandnew solutionhasresultedinacloseto 20pct.efficiencyincrease.

Danishsolutionsforjust-in-time logisticsincludesystemsforlocating andtrackingstaffandequipment, solutionsforautomatingbasicand repetitivetasks,aswellassolutionsfor guidingpatientsaroundthehospital,all ofwhichhelpavoiddelaysandpeak timesinthehospitalprocess.

Samplelogistics

Acceleratingthepatientflowisalso aboutreducingthetimefromtakinga labtestanduntiltheresultisreadyat thepointofcare.

AtHospitalofSouthernJutlandin Aabenraa,thenumberofpatientshas increasedby13pct.,butwiththenew samplelogisticssolution,thehospital hasmanagedtocopeandevenreduce theaveragelengthofstay

Intelligentsolutionsforhandling sampleshelphospitalsreducetheir sampleturnaround-timeand subsequentlyspeeduppatient diagnostics.Fullyautomated laboratoriesimprovesampleflowby handlingandsortingallbloodsamples withoutanymanualhandling,thereby minimizingtheriskoferrorsand freeinguptimeforvalue-addingtasks suchaspatientrelatedwork.

Sterilegoodsandsamplelogistics

TheCapitalRegioninDenmarkwill centralizeallhandlingofsterilegoods attwodepartmentsatRigshospitalet andHerlevHospital.Withfully automatedhandlingofsterile equipment,thetwocenterswill improvehygieneandreducetheriskof infections.Atthesametimethebudget

forpurchasingandstoringsterile equipmentwillbereducedbecauseof thejust-in-timesolution.

Thefuture

Integratedlogisticsisthenextstep. Automaticdeliveryofmedicinefrom thehospitalpharmacydirectlytothe wardsandjust-in-timehousekeeping, basedonthehospitaldischargesystem, isalreadyarealityinDanishhospitals.

Storagespace,whichisbuiltdirectly intothehospitalwalls,willprioritize shortwalkingdistances,largecoherent clinicalareasandpatientrelated functions.

Denmarkisintheprocessofbuilding 16newhighlyspecializedhospitals thatareallconstructedashospitalsof thefuture,takingintoaccountthe changingroleofhospitalsinourfuture healthcaresystem.Whileoptimal hospitallogisticsisimportantforall existinghospitals,itisvitalforthe new,largeandspecializedhospitals.

Hans Erik Henriksen Chief Executive Officer Healthcare Denmark

AddingMobilityto AddingMobilityto HEALTHCARE HEALTHCARE Via EMR-EHR Via EMR-EHR

Inthequestofreducingthebulkprocessinvolvedin

handlingtheaffairsofpatientsbythemedical practitioners,andtofacilitytheprocessofgettingclose tohandstheinformationwhichmaybeneededatthetime ofproperexaminationofpatients,thefederallaws governingwingscalledfortheuseofEMRstodesignnew waystodeliverandimprovehealthcare.Someexpertssay thegovernmentmandatesareneededtofacilitate,while othersviewthemasobstacles.

Whenyouaretoimplementasecureandanefficientsystem tomanagemedicalrecordsandgenerateinvoicesatyour office.Itwillpayoffbetterifyouconsidergoingpaperless whenmanagingelectronicmedicalrecordstoreducethe distancebetweenyouandthefilesyoumayneedatthe moment.Goingpaperlesshavetheverypotentialof streamliningthenumerousinternaloperationsandpossibly improvethepatientexperience.

TheBenefitsofEMRAccordingtotheExperts: ImprovedSafety:TheimplementationoftermsinEMRs hasthepotentialityofreducingmedicalerrorscausedby outrighthandwriting.Assumingapatientwasgivena prescriptionbythedoctorandthepatientisfoundtobe allergictoMedication,throughEMRsystems,thehealth firmandpatientcangetanalertormedicationmay harmfullyinterferewithanotherdrugthepatientisalready taking.

AffordableHealthCare:Withthepossible implementationHealthInformationTechnologyterms,the costsofhealthcanbereducedbypreventingtheduplication ofexpensivemedicaltests.Thehealthcareteamcaneasily gainaccesstoapatient’smedicalrecordinrealtimeto

determineifcostlyprocedureslikemagneticresonance imagingorcomputedtomographyscanshavealreadybeen done.

AdvancedCommunication:Medicalrecordsthatcanbe accessedbysmartphones,tablets,andcomputersmakesit easyforpatientsandhealthcareproviderstofiltermedical histories,emailquestions,lookuplaboratoryresults,and scheduleofficevisitsintermsofpreventiveandfollow-up care.

“Electronichealthrecordhelpstoincreasethespeedand reliabilityinthecommunicationanddialoguebetweenthe healthcareteam,familymembers,andpatients.For instance,somechildrenwholivethousandsofmilesaway whocanbenefitfromthecareoftheirfolksusingelectronic healthrecords,”saysSalvatoreVolpe,aprimarycare physicianinStatenIsland,NewYork.SalvatoreVolpethe chairmanofthehealthinformationtechnologycommitteeat theMedicalSocietyofNewYork.

ParticipativePatients:AccordingtotheNational Partnershipsurveyitwasrecordedthatpatientswhotake moretimeaccessingtheirhealthinformationonlinewere moremotivatedtoacttowardsimprovingtheirhealth (About71percentoffrequentusers,comparedwith39 percentoftheinfrequentusers).AtVolpe’spractice,you willfindiPadswhichareusedbythepatientstoaccessthe internetfortheirmedicalrecordsandvisitwebsitestolearn moreabouttheirmedicalconditions.

Improvedcommunityhealth:Healthinformation technologyhasbeenprovedtoimprovethepossibilitiesof aidingoverallhealthofmorethanonepersonbutalso,a

wholecommunitybyidentifyinghealthdisparities,trackingtrends,monitoringtheuseofpreventivecareandhelping patientstomanageissuesthattendtobechronic.Forexample,EMRsproviderscanusethesesystemstoidentifyandnotify patientswhoareduetotakeactionstowardspreventivesolutions,includingcolonoscopies,mammograms,prostatecancer screeningsordiabeticfootexams.

TheCriticalConcerninEMR

It'stoughtoimagineanindustryofnewgenerationthatdoesn'trelyoncomputersandcustomizedsoftwaretokeepaneyeon employeesandtherebyensurethatemployeescanworkmoreproductivelyandeffectively.Computerizationisverymuch requiredinthefieldofmedicineasthiswillhelptomanagetheenormousvolumeofdatathatmedicalpractitioners, hospitals,andclinicscreateandstoreforindividualpatients.EHRsoftwaresavestimeandmoney,andhelpsininstant communicationwithhospitals,insurers,andreferringphysicians.

Itisveryrelevantthatamedicalpracticemanagerorownerofanysuchestablishmenttodesiretheinvolvementinthe procedureofevaluatingthepossiblebenefitsandalsothedrawbacksofimplementingtheconceptofEHRsolutionsbefore totalcommitmentandpossiblyinstallingthesysteminhis/herpremises.

Thereisrapidchangewhichistakingplaceinthehealthinformationtechnologyindustry,ascitedbyDr.GlennTucker,a prominentinternistwithAttleboroMedicalAssociatessituatedinAttleboro,Massachusetts,andthechairmanofthe informationtechnologycommitteeattheMassachusettsMedicalSociety,inhisopinionsaidthatsomemandateshave“stifled innovation.”

“Itwillpleasemetoseemore[vendor]innovationintheareaofusability,andthismeanshoweasyitwillbeforaphysician tousetheEMRorEHRsystemtoprovidebetter,safercarethatwillbemoreefficient,”hesaid.“Interoperabilitytendstobe anotherconcern.Theabilitytosendinformation,easilyacrossthestreettosomeonewhoisusingadifferentelectronic systemisnexttoimpossible.”

DespitethechallengeswhichthegrowthofEMRsystems,termsandproceduresisfacing,thereisalsoagoodnumberof physiciansthroughtheirresistanceisindirectlygivingimportancetotheuseofthesesystemsandthiswillpossiblytakeover thecomfortmindofthenewgenerationofmedicalprofessionals.

“ChangeinthisfieldisinevitableaswegraduatetomoreoftheXbox-PlayStation,Smartphoneandtabletgeneration.”

Nothingthatelectronicmedicalrecordisadigitalversionoftheformalmethodofmedicaldocumentationwhichis“Paper Based”andeverybodyisbecomingsointerestedinreducingtheamountofpaperthatwillbeinvolvedintheirwork,it’s obviousthatagoodnumberofthehealthIndustrieswillbetakingpartintheimplementationofEMRandEHRsolutions.

CONTEMPORARY PREDICTIVE ANALYTICS IN HEALTHCARE

Jonathan M. Prince CEO DataSmart Soluons

Technologyinhealthcarehasneverbeenmoreimportantthanistoday,anditsroleisgrowingbythehour.The

industryhasmovedfromlabscreenanalysis,recordkeeping,andclaimsprocessingintotherealmof‘BigData’, machinelearning,predictiveanalytics,andfarbeyond.Rapidly-evolvingtechnologyiscontributinginsignificant waystomeasureandreducehealthcarecostsandimprovecarequality.Letmeillustratewithanexamplefromone company,DataSmartSolutions.

DataSmartaggregatesandanalyzesmedicalandpharmacyclaimsdata(andotherimportantsupplementaltypesofdata outlinedbelow)tocreateastatistically-reliableriskscoreforindividualsthatbelongtoemployerhealthplans.Theserisk ® scores,producedinconjunctionwiththeJohnsHopkinsUniversityACG system,areforward-looking,orpredictive,in nature.Thegoaloftheanalysisistospotemerginghigh-costclaimantswellbeforetheirconditiondeterioratesand becomesadvancedorlife-threatening.

Onceriskscoresareassignedtoeachplanparticipants,nursecliniciansandpopulationriskmanagersprioritizethe participantsanddeployinterventionresourcesindescendingorder,addressingthehighestriskplanparticipants.Inthis manner,healthcareprofessionalspreventhigherriskcasesfromescalatingintomajorcrisesandhigherexpensesforthe plan.

Lastly,acarefulstudyofthedataenablesimportantrefinementstobemadetobenefitplanstoencouragehigher utilizationofthehighest-valuemedications,thebestfacilities,andthebestproviders.

Interestingly,Pareto’sLaw(alsoknownasthe‘80/20Rule’)appearsindramaticfashioninpopulationriskmanagement andhealthcare.Inshort,asmallpercentageofthecoveredlivesaccountsforadisproportionateshareofplanexpenses. Mostwellnessprogramsfocuseffortsuponthemasses(i.e.the80%).However,inactuality,mostofaplan’sexpenses originatewithasmallnumberofplanparticipants(i.e.the20%).Infact,asfewas3-5%ofplanparticipantsroutinely accountforone-halfofahealthplan’sexpenses,somewhatregardlessoftheplan,thegeography,orthedemographicsof thepopulation.Imaginetheimpactonhealththatcouldberealizedifthe3-5%couldpreventtheirconditionfrom deteriorating.Earlydetectionofthissmallpercentagealsopresentsagreatopportunitytolowertheoverallcostofcare. Diabetes,cardiacconditions,andevensomecancerscanbereadilyidentifiedinearlystatesbythepro-activeuseof predictiveanalytics.

Asimilarstatisticofsimilarimportancerelatestothenon-repetitivenatureofhighcostclaimants.Approximately60% ofthoseappearingonlistofhighest-costclaimantsinagivenplanyearappearonthislistforthefirsttime.Inshort,the majorityofthehighest-costclaimantsfromyear-to-yeararenewtothelist.Thiscreatesachallenge,becausemedicaland pharmacyclaimsdatadoesnotexistformanylivesontheplan,andevenifitdid,itwouldnotprovidesufficientdatato predictfuturerisk.Further,approximately20%ofplanparticipantswillnotenterthemedicalsysteminanygivenyear, andwithinthatgroup,therearemanytickingtimebombs.

Toaddressthisproblem,planmanagersoftenincludefinancialincentivestoparticipantstoencouragethemtoengagein activitiesthatgenerateusable,statistically-significantdata.Valuablesourcesofdataincludebloodscreens,biometric information,visiontestsandspecialhealthriskquestionnaires.Asthisdataiscollectedandanalyzed,itcanserveasa surrogateformedicalclaims.Today,leadingedgeanalyticscompanieshavefoundthatmanynon-claimselementsare less-expensive,moreaccessible,andmorestatistically-valuablethanclaimsrecords.Inshort,themorerelevantdata available,thebetter

Asafinalthought, the actions taken [uponanalytically-derivedfindings]areatleastasimportantasthefindings themselves.Thosewholaytheseriskmarkersasidearenobetteroffthanapersonwhofailstofollowhisownadvice. ThescientistJamesE.Talmageoncetoldanunconfirmed,butillustrative,storyinvolving“…anepidemicofcholeraina greatcityinwhichascientificmanprovedtohisownsatisfaction,bychemicalandmicroscopictests,thatthewater supplywasinfected,andthatthroughitcontagionwasbeingspread.Heproclaimedthefactthroughoutthecity,and warnedallagainsttheuseofun-boiledwater.Manyofthepeople,althoughincapableofcomprehendinghismethodsof investigation,farlessofrepeatingsuchforthemselves,hadfaithinhiswarningwords,followedhisinstructions,and escapedthedeathtowhichtheircarelessandunbelievingfellowssuccumbed.Nevertheless,inamomentofforgetfulness hedrankoftheunsterilizedwater,andsoonthereafterdied,avictimtotheplague.”

Themoraltothestoryisthatinformationisonlyasvaluableasthemeasurestakentoactuponit.Nowhereisthismore trueandapplicablethaninhealthcare.

The Next Frontier of INNOVATION in the Pharmaceutical Industry

Thepharmaceuticalindustryispassingthroughhopefulandturbulenttimesatthesametimetoday.Ononehand,the industryisfacingrisingoppositionfromcustomerswhowishtopayasasinglepayer.Ontheotherhand,great innovationsarehelpingpharmaceuticalindustrymeetnewcustomerstogrowrevenues.Anexampleofthelater developmentisthedigitalmobiletechnologywhichhelpstheindustrycollectlargeamountofdatatoformanunparalleled understandingofhealthcare.Additionally,todaythepharmaceuticalindustryisinapositiontomakeastatementtothelarger publictosealitsplaceastheidealproviderofhealthcareinthelongrun.ThePharmaceuticalindustrycanfindaharmonious balancebetweentheturbulenceandopportunitiestoclaimthethroneofagreathealthcareproviderwithrealinnovation today.

Currently,thehealthcareindustryfocusesonR&Dwhichcanimmediatelybeturnedintoproductstoearnrevenues. An exampleofthiseconomicdevelopmentisthelargenumberofmedicalsolutionsavailablewhichtreatcommonillnessessuch ascold,fever,headache,etc.andareusuallyavailableasoverthecountermedicineforpatients.Thiseconomicactivityis governedbypatientswhopayasindividuals.Thiseconomicmodelisinlinewithnaturalprinciplesthatadvocatethatselfinterestisthemotivatorofeconomicactivityandcompetitionistheregulator. However,thereisaneweconomicexpectation ofpatientswhichcouldbettershapethefuture.Ifpatientspaidasasinglepayer,thegovernmentcouldinvestinmoreR&D taxdollarsintothefutureintheformofgrantsorsubsidies.Withouttheinfusionofsuchinvestments,realinnovationwould bedifficultasrealinnovationrequirescompaniestooperateintheareaofabsoluteuncertainty,whichcanbeanightmare fromthepointofviewofshareholders.

UntappedInnovativeOpportunities

Inthepharmaceuticalsector,thenaturaleconomicforceshavenotyetfoundsolutiontodeadlydiseaseslikeHIV,multiple formsofcancers,andseveralothers.Theprimaryreasonfortruelifesavinginnovationbeingexpensiveisthattrueinnovation operatesintheterritoryofabsoluteuncertaintyandhenceonecannotsetatimelineinprincipleinordertoachievedesired results.Furthermore,thisisalsotheprimaryreasonwhydeadlydiseaseswhichpromiselucrativerevenuesmayneversee realinvestmentbyindividualswhoaregovernedbyself-interest.Individualself-interestleavesbreathingspaceforIndividual desireforhappinessandislikelytobesusceptibletoindividualweaknesses.Ontheotherhand,ifcompaniesreceived fundingforinnovationthroughalegitimatepublicentitylikethegovernment,itcouldinvestininnovationforthelongterm

growthofasociety.Suchcollaborationwouldhelpthe pharmaceuticalindustrytofindsolutionsthatseparatelife anddeathinameaningfulmannerinthesociety. Onthe otherhand,theindividualcompanieswhichfindasolution tograveillnessescanalsomonetizetheseinnovations. Somesuchtrendinginnovationsarementionedbelow

PreciseMedicine

TodaythePharmaceuticalindustryfacesstifflegalpenalties foroverdosingapatientwithaparticularmedicine.The goodnewsissoondoctorswouldgainaccesstogenomes whichhelpsmapouttheindividualmedicalhistory.This makesitpossibletodeliveraperfectandprecisedoseof medicinetoapatient.Genomeprojectsaregathering momentum,largelyduetoaninitiativeoftheObama administration,whichgavethegrantof$215millionto PrecisionMedicineInitiative. Grantsliketheseand

Articial Intelligence

ArtificialIntelligence(AI)

Precise Medicine

projectslikethesewouldmakeitpossibletodevelop personalizedmedicalsolutionswhicharenearperfectfor allpatients.

DataGathering

Itisimportantfordoctorsandmedicalresearcherstohave accesstorealintelligentdatainordertomakeobjective observationsandproduceinsightfulinnovation.Suchdata gatheringandgenerationhasbecomemucheasierthanksto mobileapps.Today,severalmobilephonesinclude technologiesthatcantrackmovement,sensevarioushealth indicatorsandmeasurethehealthofpatientsandprovide thedatatodoctorsandresearcherstobetterunderstandtheir patients.Suchdataappsaremakingitpossibletocreate genesequencingandlivehealthmonitoring,whichcould haveonlybeendreamtaboutinthepast.

AIhasbecometheguidinglightformanyindustries.The Pharmaceuticalindustryisnotanexceptiontothisrule. Supercomputersandmachinelearningaremakingit possibleforresearcherstodetectpatternsingenes,diseases andrespondtothemwithappropriatesolutionsatablazing quickspeed.ManysuchAIprojectsarecurrentlyhelping thePharmaceuticalindustryonthepathofinnovation.One primeexampleofthistechnologyinactionistheIBM Watsonwhichhasdemonstratedlearningcapabilitiesand absorbsmillionsofpagesofmedicalliteraturetomakethe industryreachthepinnacleofcompetitivesuccess. Therearemanymoreinnovationswhicharereshapingthe futureofthePharmaceuticalindustry.Someofthese include3DPrinting,Nanotechnology,Virtualmeetings betweendoctorsandpatients,etc.Innovationisopeningup newdoorsofopportunitiesforeveryindustryand companieswhichfollowthepathofinnovationwillfinda goldenarchtobuildagreatfutureforthem.However,itis importantfortheindustrytosecureitslongterminterestby positioningitselfastheidealproviderofhealthcareservices intheshortrun.

Data Gathering

Sciformix:

Driving Innovation Through Deep Scientific Knowledge and Technology Expertise

Lifescienceorganizationsareconfrontingaheap ofpressurefrominvestors,stakeholders, regulatoryexperts,patients,andthehealthcare industryastheyareexpectedtoproducehigh-quality medicalproductsaroundtheglobe.Asaresult, organizationsturntooutsourcingvendorstohelpthem addresstheseconstraints.However,theirrequirements havegrownsignificantlyinthelastdecadeastheyseek greaterscientificknowledgeandinnovationcapabilities thanwhatcustomaryBusinessProcessOrganizations (BPOs)orContractResearchOrganizations(CROs)are abletooffer

Sciformix,aleadingscientificknowledge-based organization,isfillingthegapsleftbytheseprovidersto provideahigherlevelofengagement,qualityandvalue duetoitsthoughtleadership,deepdomainknowledge, andtechnologyinnovation.Foundedoveradecadeago, Sciformixhasbeenabletosuccessfullyprovideprocess, technology,andconsultingservicesto biopharmaceutical,genericpharmaceutical,consumer products,medicaldevices,andotherhealthcare companies.Today,Sciformix’sabilitytointegrate scientificandtechnologyexpertisewithqualitydriven processesprovidesvaluetoitsclientsthroughoutthe entiredrugdevelopmentcycle.Theirclientsaregaining anupperhandandarepoisedtowitnessgreatersuccess andbusinessfocusbyproactivelymanagingtheir productswithstate-of-the-arttechnologyandbest-inclassservices.

Amiditsvariedrangeofspecializedservices,someareas thatdistinguishSciformixare Safety & Risk Management, Clinical Development, Regulatory Affairs & Regulatory Operations, Real World Evidence & Market Access, and Technology Services Thecompany helpsclientsacceleratetheirbusiness,drivehigherlevels

ofperformanceandfacilitateinnovationbyemploying best-in-classstrategies,technologiesandexpertise.

AVisionthatPavedtheWayforGrowth

Thefoundersofthecompany—AjitNagral,Founder& Chairman,andChitraLele,Co-founder&Chief ScientificOfficer—hadthevisionofestablishinga companythatwouldprovidespecializedscience-based servicestopharmaceuticalorganizations.Although,the foundersinitiallyfocusedonofferingsinSafety&Risk ManagementandBiometrics,theygraduallyexpandedto includeMedicalWritingandRegulatoryAffairsto supporttheirclients’growingneeds.Soonenough,they introducedClinicalDevelopment,RealWorldEvidence &MarketAccessandTechnologyServices,greatly expandingtheirofferingsandexpertise.

HeadquarteredintheUS,Sciformixhasoperationsin Europe,IndiaandthePhilippines.Byemployingover 1,000expertsaroundtheworldwithdiverseskill-sets, Sciformixisabletooffersitsclientsflexibleandcosteffectivedeploymentmodels(on-shore,off-shoreand hybrid)tomeettheiruniqueneeds.Sciformixis recognizedbytheindustryforitsdepthofscientific expertise.

SingularlyDedicatedtotheLifeScienceIndustry

Throughalltheseyears,though,themissionofthe Company—topartnerwithlifesciencecompaniesto providehighqualityscientificexpertisethatdelivers betterqualityoutcomesandimprovedefficienciesacross theentireproductlifecyclewiththeultimateobjectiveof improvingqualityofhealthcareforpatients worldwide—hasn’tchangedabit.

SinceitsfoundationSciformixhasbeensingularly dedicatedtothelifescienceindustry Therefore,its

people,processes,andtechnologieshavebeentailored andoptimizedtomeettheindustry’suniqueneeds. Quality,compliance,andscientificexcellencearethe company’scornerstonesanditsexperiencedsubject matterexperts(SMEs)andthoughtleadersareaclear differentiator,enablingSciformixtoprovideunique insightandvaluetoitsclients.Thecompanydelivers consistentqualityandcomplianceacrossitsservicesby employingscientificrigorincombinationwith streamlinedprocesses,optimaltechnology,andefficient peoplepractices.

Oneofthemajorchallengesorganizationsfacetodayis howtoeffectivelyintegratethecomplexitiesoftwo seeminglydisparatefunctions-technologyandscienceacrossallphasesoftheproductdevelopmentlifecycle. Typically,outsourcingorganizationsexcelinoneorthe other,butnotboth.Sciformixhasrecognizedthe synergiesofanintegratedstrategyandunified communicationprocesstohelpitsclientsdeploy technologyforbetterinsight,analytics,andcompliance.

Diversification,GrowthandGlobalReach

Sciformix’slong-termstrategyfocusesonevolvingand enhancingitsserviceandtechnologyofferings, broadeningitsglobalreachandgrowinganddiversifying itsclientandrevenuebase.Thiscanbeseenintherecent launchofseveralcloudbasedsafetytechnologyservice offeringsandexpansionofitspresenceinEuropewitha newcallcenteroperationinRomania.Sciformixisalso

lookingtopenetrateunderservedmarketsinAsiaPacific suchasSouthKoreaandTaiwan.Inaddition,the biosimilarsmarketisexpectedtogrowto$20Bby2020 andcompanieswillneedSciformix’ssupporttoenter bothestablishedandemergingmarkets.Sciformixis lookingatthismarketastutelyasanareaofgrowthand furtherexpansion.

MeettheCEO

ManishVinayakSoman,PresidentandCEOof Sciformixhasover26yearsofprovenexperiencein overseeingIToperationsthatencompass program/projectmanagement,consultingservices, systemsdevelopment&implementationandbusiness operations;andhasmanagedP&L’sandBalanceSheets forover15years.Hehasheldleadershippositions acrossmultiplegeographies.Hispastexperience includestenuresasCEO&ManagingDirectorof DeloitteIndia,GlobalBusinessLeaderforITatGenpact (formerlyaGEcompany),COOforPatniComputers andDirectorforBestShoreOperationsinEMEAforHP EnterpriseServices.

www.sciformix.com

Manish

Soman President & CEO

Our experts, physicians, scientists, and statisticians dive deep into data to provide thorough analysis and insight to help clients make faster and more informed decisions so that they can deliver safer and more effective medical products around the world.

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