“HORTUS CONCLUSUS” is an architecture's Research Thesis that explores the current food supply, the infrastructure of cities and the potential future of agricultural production within urban centers through Urban and Vertical Farming, in the context of sustainability. Urban Agriculture has great potentials and that a humanity open in dealing with the future challenges can resolve the foreseeable famine problem and sustain a balanced environment. The Thesis was presented in January 2019 at the Department of Architecture in University of Thessaly and was supervised by Professor Iordanis Stylidis.