BIOPRON – PROPER SUPPORT OF INTESTINAL MICROBIOTA AND IMMUNE SYSTEM
BIOPRON BABY+ DROPS WITH CLINICALLY PROVEN STRAINS Lactobacillus rhamnosus (LGG®) - the world’s best documented probiotic strain
BIOPRON® Baby+
∂ Strain deposit number: ATCC53103. ∂ Lactobacillus rhamnosus (LGG®) is the world’s best documented probiotic strain. It has been used in food and dietary supplements since 1990, has been described in more than 1000 scientific publications and studied in more than 300 clinical studies with no reported side effects. ∂ The US Food and Drug Administration (FDA) has designated the LGG® strain as Generally Recognized As Safe (GRAS notice, 28.5.2008). ∂ In Europe, Lactobacillus rhamnosus has been granted Qualified Presumption of Safety (QPS) status since 2007 by the European Food Safety Authority (EFSA) – a status granted on species level.
Bifidobacterium animalis subsp. Lactis - proven by respiratory tract infections Clinical, double blinded, placebo controled study13 with 109 participants (1-2 months of age) confirmed 30% reduction of RTIs in group with probiotics. Children have 10x109 CFU daily for 6-7 months. Number of respiratory infections in 8 months old babies (after 6-7 support with Bifidobacterium animalis ssp. lactis)13
100
-30%
80
%
60
PACKAGING
10 capsules
0,25 ml (7-8 drops)/day
DOSAGE
1 capsule/day
From birth
AGE
From 12 months
amount/ 0,25 ml
Daily dose contains:
Probiotic complex (2 strains of live microorganisms): Lactobacillus rhamnosus GG Bifidobacterium animalis subsp. Lactis BS01 Food Supplement
109
2,5x CFU*
1,5 µg (60 IU)
Vitamin D3
% DRI**
-
30
amount/ 1 cps.
% DRI**
3x 109 CFU*
-
Inulin
150,0 mg
-
Fructooligosaccharides
50,0 mg
-
Vitamin C
24,0 mg
30
Vitamin B6
0,35 mg
25
Daily dose contains: The Probiotic complex (4 strains of vital microorganisms): • Lactobacillus rhamnosus (GG) • Lactobacillus helveticus (Rosell®-52) • Bifidobacterium infantis (Rosell®-33) • Bifidobacterium Bifidum (Rosell®-71)
Biopron Baby+ and Kids+ are especially beneficial for babies: ∂ Preterm born or born by cesarien section ∂ Which were or are not breastfed ∂ With and after usage of antibiotics ∂ With acute and chronic diarrhea ∂ With any other risk or symptom of dysbalanced microbiom (frequent sickness, crying/fussiness, irritated skin / AD, allergy risk in family) *CFU – colony-forming units, **daily reference intake, – not established
o i l o f t r o p Unique g n i t t e s r e p for pro a t o i b o r c i m of gut plements
p Food Su
40
FIRST
20
DAYS
day 293 day 758
e f i L f o e s o d y l i a d r u Yo . y b a b r u For yo
First 1000 days of new life are the most important for the healthy development and influences the whole life. FIRST
0
placebo
Bifidobacterium animalis ssp. lactis
Children were using 10x109 CFU daily during 6-7 months. Observed symptoms were cold, congested nose, cough and dyspnoea. *
10 ml drops
COMPOSITION
Clinical studies ∂ Tested in clinical studies from newborn preterm infants to elderly populations in dosages up to at least 100 billion CFU/day, with no reported serious adverse events. ∂ May reduce respiratory tract challenges7. ∂ May reduce crying and fussiness in preterm born infants8. ∂ May alleviate symptoms of irritated skin, can significantly alleviate symptoms of AD9. ∂ Is recommended in antibiotic associated diarrhea10. ∂ Is recommedned in acute diarrhea11. ∂ Is recommended to use for prevention of nosocomial diarrhea12.
BIOPRON® Kids+
Deposit strain number: ATCC53103
1. Neu J., Rushing J., Clinics In Perinatology, 2011 2. The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation, Amy Langdon et al, 2016 3. Effect of Breast and Formula Feeding on Gut, Microbiota Shaping in Newborns, Federica Guaraldi, 2012 4. Molecular Studies of Fecal Anaerobic Commensal Bacteria in Acute Diarrhea in Children, Balamurugan, 2008 5. Diet rapidly and reproducibly alters the human gut microbiome, Lawrence A. David, 2014 6. Probiotics and prebiotics: prospects for public health and nutritional recommendations Mary Ellen Sanders, Irene Lenoir-Wijnkoop, Seppo Salminen, Daniel J. Merenstein, Glenn R. Gibson, Bryon W. Petschow, Max Nieuwdorp, Daniel J. Tancredi, Christopher J. Cifelli, Paul Jacques and Bruno Pot 7. Hatakka et al. 2001, Hojsak et al. 2010a, Hojsak et al. 2010b 8. Pärtty et al. 2013 9. Kirjavainen, 2003 10. Szajewska H. et al, 2016 11. Szajewska H et al. 2014 12. Hojsak et al, 2010 13. Taipale T. et al., 2011 * 1000 days is period from conception (begining of pregnancy) till aprox. 2 years of children life. In this period is developed and set also gut microbiom.
DAYS
Food Supplements. With vitamin D, B6 or C that contributes to the normal function of the immune system.
www.biopron.com Internal use only
(day 271-635) Baby+ Proper development of intestinal microbiota and immune system
(day 636-1000) Kids+ Proper support of intestinal microbiota and immune system