Job#: 301542c Date: 08-11-07
12:31:17
Fourth Edition
Toxicology about the book…
about the author... JOHN A. TIMBRELL is Emeritus Professor of Biochemical Toxicology, King’s College London, London, UK. He received his Ph.D. in drug metabolism from the University of London, London, UK. Dr. Timbrell is the founding editor of the publication Biomarkers and has served on the editorial board of serveral journals. His main topics of interest include the role of taurine in detoxication/protection, toxicology of the liver, mechanisms of toxicity of compounds and biomarkers of chemical-induced dysfunction. Dr. Timbrell is the author of Introduction to Toxicology, Third Edition; and Study Toxicology Through Questions. Printed in the United States of America
of
New to the Fourth Edition: • reorganized sections that cover basic principles followed by sections on different types of toxicity • extensive use of examples throughout and numerous explanatory diagrams • new material on risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen, peroxisome proliferators, domoic acid, benzene, adriamycin, primaquine, biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, botox, and more • questions with answers for each chapter for review and self-checking • expanded and updated chapter bibliographies
Principles
Principles of Biochemical Toxicology, Fourth Edition thoroughly explains doseresponse relationships, disposition and metabolism, and toxic responses to foreign compounds, and presents detailed examples to make the mechanisms of toxicity more accessible to students encountering the subject for the first time. Comprehensive in scope with a clear and concise approach, the text includes summary sections, questions and model answers, and thoroughly revised artwork that serves as an essential aid to learning and teaching.
Biochemical Toxicology
This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research in the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards.
Principles of
Biochemical Toxicology Fourth Edition
Timbrell
7302
John A. Timbrell
Timbrell_978-0849373022.indd 1
10/23/08 9:53:48 AM