The Gazette by The Johns Hopkins University

o ur 4 1 ST ye ar

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Covering Homewood, East Baltimore, Peabody,

Elementary school players come

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together at Homewood for CTY

for a send-off soiree at one of

Baltimore-Washington area and abroad, since 1971.

citywide tournament, page 8

their favorite haunts, page 4

May 29, 2012

The newspaper of The Johns Hopkins University

Volume 41 No. 36

E V E N T

homewoodphoto.jhu.edu

Hail to our supergrads

Newly minted graduates and participating faculty leave Homewood Field following Thursday’s Commencement ceremony, at which 7,529 degrees were conferred on students from the university’s nine academic divisions.

136th academic year comes to a close under blue skies and sunshine By Greg Rienzi

The Gazette

he Johns Hopkins University Commencement speakers evoked an optimistic spirit, superheroes and even pizza as they imparted words of wisdom, and humor, to the Class of 2012. On a sunny spring day that had begun with threatening gray clouds, President

Ronald J. Daniels conferred degrees on 7,529 graduates at the Commencement ceremony marking the end of the university’s 136th academic year. Thousands filled Homewood Field seats for the Thursday morning ceremony that featured a raucous crowd of supporters. Many graduates—with summer clearly on their minds—wore sunglasses, sandals and shorts with their robes as they sat in the low80s heat. Befitting the creative and talented group, many graduation caps were decorated this year, the embellishments ranging from flowers and a bedazzled “Thanks to Mom and Dad” to a Blue Jay perched on top. One student spelled out her next goal in life: “Future MD.” In a tradition begun in 2010, the under-

In Brief

Peabody shuttle stop change; JH-U-Turn; ‘Gazette’ summer schedule; Osher celebration

graduates from the Krieger School of Arts and Sciences and the Whiting School of Engineering first gathered on the Keyser Quadrangle to take a ceremonial “final walk” across campus, passing through the Freshman Quad, where their academic journey Find scores more photos of the day’s events online at facebook.com/ johnshopkinsuniversity.

started, to reach Homewood Field. They were joined on their walk by undergraduates from the Peabody Institute and the School of Nursing. All other degree candidates entered from the Athletic Center. In his address, Daniels joked with the

graduates about the trauma of leaving Johns Hopkins, and then wove into his talk two summer blockbusters: The Hunger Games and The Avengers. In each film, the main characters face grave odds and a path filled with peril as they strive toward their goal. In The Hunger Games, young people are pitted against each other. In The Avengers, a group of superhumans must come together and unite their powers for the good of society, and to literally save mankind. Daniels told the graduates that like these fictional heroes, they must choose the “us” over the “I” and face humanity’s great challenges together.

C A L E N D AR

Blackboard workshops; ‘Traditional Beverages’; Charles Village Festival; blood drive at Eastern

Continued on page 5

6 6 7

Job Opportunities Notices Classifieds

2 29,15, 2012 2 THE THE GAZETTE GAZETTE •• May August 2011 I N B R I E F

One Peabody shuttle stop eliminated as of today

n an effort to improve shuttle operations, starting today, May 29, the Peabody campus will have only one southbound stop, located at St. Paul Street and Mount Vernon Place; the stop at the southeast corner of St. Paul and Centre streets will be eliminated. The route is being altered so that buses continue on St. Paul Street and turn left onto Orleans, improving the safety and efficiency for all passengers.

JH-U-Turn gives unwanted items a second chance

nd-of-the-year unwanted clothing, furniture, electronics and household items may go into the dumpster at some college campuses, but at Johns Hopkins, they get a second chance by being donated to the annual JH-U-Turn yard sale. Shoppers get great prices (cash only), and the proceeds benefit the Johns Hopkins Neighborhood Fund and the United Way of Central Maryland. This year’s sale is set for Saturday, June 9, in Homewood’s Ralph S. O’Connor Recreation Center, and the doors stay open from 8 a.m. until everything’s gone. Volunteers—who sort, test, clean items and work during the sale—get to shop a half-hour before the crowds arrive. To volunteer, contact Carrie Bennett at liaison@jhu.edu. More information, including a sample price list, is online at web.jhu.edu/liaison/UTurn .html.

Osher at Johns Hopkins steps back into the 19th century

n afternoon of 19th-century music and dance will honor and recognize the anniversary of the War of 1812 and the Civil War sesquicentennial while celebrating the Osher Lifelong Learning Institute at Johns Hopkins University. The institute was created in 1986 as the Evergreen Society with a mission to enhance the leisure time of semi-retired and retired individuals. Osher, a membership community, offers an array of noncredit courses, lectures and activities, along with opportunities for social interaction, during fall and spring semesters. The program is offered in Baltimore and Columbia, Md. The celebration takes place from 2 to 4 p.m. on Sunday, June 10, in Homewood’s Shriver Hall; a reception follows. For information, go to osher.jhu.edu or call 301-2947058.

Traditional punch gets a redo by four top Baltimore mixologists

erhaps the first “cocktail” of early America, punch is thought to take its name from the Indian word panch for five, referring to the five ingredients of which

Editor Lois Perschetz Writer Greg Rienzi Production Lynna Bright Copy Editor Ann Stiller Photography Homewood Photography A d v e rt i s i n g The Gazelle Group Business Dianne MacLeod C i r c u l at i o n Lynette Floyd Webmaster Lauren Custer

it was composed: something sour, something sweet, something strong, something weak and spices. Homewood Museum puts this historical beverage front and center for its 16th annual Evening of Traditional Beverages, to be held from 6 to 8 p.m. on Thursday, June 7, on the museum’s lawn (rain location: Glass Pavilion). Corey Polyoka, chief mixologist at Woodberry Kitchen, will provide some background on the beverage along with three original, high-octane punches, featuring rare or unique Maryland spirits, created especially for this event by members of the newly formed Baltimore Bartender’s Guild: Polyoka, Brendan Dorr of B&O American Brasserie, Doug Atwell of Rye and Perez Klebahn of Mr. Rain’s Fun House. Snacks will be provided by Woodberry Kitchen. Due to event popularity and limited space, reservations are requested by Friday, June 1; walk-ins are subject to availability. To purchase tickets, which are $35 for museum members and $45 for nonmembers, call 410516-5589 or go online to brownpapertickets .com/event/244027. Attendees must be 21 or older.

Charles Village Festival set for first weekend in June

he Charles Village Festival returns to the Wyman Park Dell on Saturday and Sunday, June 2 and 3, with live entertainment on two stages, kids’ activities, crafters and beer/wine and food vendors, and a neighborhood garden walk. Admission is free to the two-day event, which celebrates the neighborhood and is a major fundraiser for multiple civic resources in the area. Johns Hopkins is one of the principal sponsors.

‘Typographer’s Dream’ on stage at Swirnow Theater

he Homewood Arts Program will be hosting a local professional theater company for two weeks in the Mattin Center’s Swirnow Theater. From May 31 through June 16, Iron Crow Theatre will be presenting The Typographer’s Dream, which the company describes as an “unusual, funny, unnerving play.” Details about the play, ticket information and dates and times of performances are available online at ironcrowtheatre.com.

‘The Gazette’ begins biweekly summer schedule today With this issue, The Gazette begins its biweekly summer schedule. The next issue will be published on June 11. Calendar items and classifieds should be submitted by noon on Monday one week before publication by email to gazette@ jhu.edu, fax to 443-287-9920 or online at gazette.jhu.edu.

Contributing Writers Applied Physics Laboratory Michael Buckley, Paulette Campbell Bloomberg School of Public Health Tim Parsons, Natalie Wood-Wright Carey Business School Andrew Blumberg, Patrick Ercolano Homewood Lisa De Nike, Amy Lunday, Dennis O’Shea, Tracey A. Reeves, Phil Sneiderman Johns Hopkins Medicine Christen Brownlee, Stephanie Desmon, Neil A. Grauer, Audrey Huang, John Lazarou, David March, Vanessa McMains, Ekaterina Pesheva, Vanessa Wasta, Maryalice Yakutchik Peabody Institute Richard Selden SAIS Felisa Neuringer Klubes School of Education James Campbell, Theresa Norton School of Nursing Kelly Brooks-Staub University Libraries and Museums Brian Shields, Heather Egan Stalfort

The Gazette is published weekly September through May and biweekly June through August for the Johns Hopkins University community by the Office of Communications, Suite 540, 901 S. Bond St., Baltimore, MD 21231, in cooperation with all university divisions. Subscriptions are $26 per year. Deadline for calendar items, notices and classifieds (free to JHU faculty, staff and students) is noon Monday, one week prior to publication date. Phone: 443-287-9900 Fax: 443-287-9920 General e-mail: gazette@jhu.edu Classifieds e-mail: gazads@jhu.edu On the Web: gazette.jhu.edu Paid advertising, which does not represent any endorsement by the university, is handled by the Gazelle Group at 443275-2687 or gazellegrp@comcast.net.

May 29, 2012 • THE GAZETTE

O U T R E A C H

Johns Hopkins Neighborhood Fund helps 21 local nonprofits By Karen Clark Salinas

Work, Life and Engagement

wenty-one local nonprofit organizations have received financial support from the Johns Hopkins Neighborhood Fund in the form of grants totaling nearly $263,000. Sixty-six agencies applied in February for funding, with requests totaling nearly $800,000 for projects that address the needs of communities around Johns Hopkins campuses in the areas of public safety, health, employment, education and community revitalization. The Neighborhood Fund was created in 2007 to support nonprofits that serve the communities surrounding Johns Hopkins campuses and that are associated with Johns Hopkins through institutional involvement or affiliation with faculty, staff, retirees or students. Donations to the Neighborhood Fund are accepted through the annual Johns Hopkins United Way campaign. Charlene Hayes, the university’s vice president for human resources, has been involved with the program since its inception. “The Neighborhood Fund is the crown jewel of our community programs,” she says.

“It provides every Johns Hopkins employee an opportunity to respond en masse to a clearly articulated community need. Johns Hopkins is a part of Baltimore, and the Neighborhood Fund demonstrates our commitment to the community in which we live, work and study.” Grant applications were reviewed by the fund’s Allocation Committee, which comprises a cross section of Johns Hopkins employees and is chaired by Frank Bossle, executive director of JHI Internal Audits. “It is extremely rewarding to see the generosity of my fellow employees in supporting very worthy organizations in our neighborhoods,” Bossle says. “The Allocation Committee was impressed and pleased with the quality of the applicants.” Since its inception, the Neighborhood Fund has awarded 79 grants totaling more than $816,000. The 2012 recipients and how they will use their funds are as follows: • AIDS Interfaith Residential Services will offer young people transitional and permanent housing, along with services and training opportunities, through the City Steps program. • Baltimore Reads will offer reading, English for Speakers of Other Languages and GED preparation across Baltimore through the Portable Classrooms program.

First JHU–Clinton Health Access Initiative fellows named

he Johns Hopkins University and the Clinton Health Access Initiative have joined forces to develop two fellowships for Johns Hopkins students to work in CHAI’s in-country programs. CHAI is a global health organization committed to strengthening integrated health systems in the developing world and expanding access to care and treatment for HIV/AIDS, malaria and tuberculosis. Its solution-oriented approach focuses on improving market dynamics for medicines and diagnostics, lowering prices for treatment, accelerating access to lifesaving technologies and helping governments build the capacity required for high-quality care and treatment programs. Established in 2002 by former President Bill Clinton as the Clinton HIV/ AIDS Initiative, CHAI was drawn to Johns Hopkins because of the strength of its School of Public Health and its undergraduate public health major, but the program is open to all JHU students. The fellowship involves a three- to six-month placement at a CHAI site overseas. Students are supported by the Johns Hopkins Center for Global Health travel grant program and also receive support from the CHAI site.

The first two fellows in the program are Lauren Brown and Emily Chien. Brown received a bachelor’s degree in public health, with a minor in economics, last week. Chien received a master’s degree in public health from the Bloomberg School and an MBA from the Carey Business School; she also holds a bachelor’s degree in molecular, cell and developmental biology from UCLA and worked at Deloitte Consulting as a business technology analyst and a consultant. Both Chien and Brown will be working on the evaluation of implementation of point-of-care CD4 counting technology for HIV care programs. CD4 is the crucial diagnostic test to determine eligibility for antiretroviral therapy. Access to CD4 testing is key in guiding appropriate scale up of HIV treatment. The POC CD4 technology, which is smaller and significantly easier to use than traditional CD4 machines, will allow lower-level facilities to monitor CD4 without having to send blood samples to larger facilities. This new technology, if optimized, is expected to reduce mortality and significantly extend life for HIV-infected people. Brown will be working in Lesotho in southern Africa, and Chien will be in Uganda in East Africa.

Parking permit rate changes set at Homewood and Eastern

ew permit parking rates go into effect on July 1 for parking lots and garages on the Homewood and Eastern campuses. Since parking is paid in advance, these changes will be enacted on the June 29 payroll cycle. All surface lots are $59 per month. Faculty hangtag parking and general garage parking are $94 per month. Reserved parking spaces at the West Gate, San Martin and South garages will be $125 per month. Reserved surface lot parking is $83 per month. Eller-

slie satellite parking is $36 per month. Current customers satisfied with their parking permit do not need to act. Anyone wishing to purchase a permit, cancel a permit or change parking locations should contact the Homewood Parking and Transportation Office, located in the South Garage, by emailing parking@jhu.edu or calling 410-516-PARK. Parkers are advised that many Homewood lots and garages are at capacity, and several locations have short wait lists.

• Baltimore Symphony Orchestra will provide year-round during- and after-school music education and mentoring to an additional 40 pre-K and kindergarten students in Baltimore City’s urban neighborhoods through the OrchKids program. • Baltimore Urban Debate League will use in-school hours, after-school workshops, weekend tournaments and summertime programming to enrich the academic experience of the city’s youth through its elementary and middle school debate program. • Caroline Friess Center will fund a career coach to initiate contact with students and follow up with graduates to assist with employment issues. • East Baltimore Development Inc.’s Elev8 Baltimore initiative will provide school-based health services and out-ofschool programs to ensure that middle grade students achieve success in school and in life through the Children’s Defense Fund Freedom Schools. • Helping Up Mission will provide healthy meals to men participating in a long-term residential recovery program. • Higher Achievement Baltimore will help at-risk youth transition successfully through middle school and place them in top high schools that get them on track to four-year colleges through the Afterschool Academy program at the East Baltimore Achievement Center. • Historic East Baltimore Community Action Coalition will assist with the operating costs of a computer-learning center that will provide instructor-assisted and selfpaced computer skills training for local residents. • Incentive Mentoring Program will continue its work with students who exhibit poor academic performance by stabilizing their school and home lives. • International Rescue Committee’s Pregnancy Support Program will ensure that newly resettled refugees from politically unstable countries are supported during pregnancy and birth. • Living Classrooms Foundation will support the Safe Streets program, a public health campaign that aims to reduce violence in several Baltimore communities. • Manna House will employ a part-time cook to expand meal serving from only weekdays to seven days a week. • Marian House will provide immediate housing, meals, personal supplies, addiction recovery programs, transportation, medical

care referrals and other services to homeless women and their children. • Maryland New Directions will offer two-week workshops and one-on-one counseling to low-income Baltimore residents to enhance their employment readiness skills. • Meals on Wheels of Central Maryland will deliver meals for one year to a maximum of 15 homebound, frail and elderly individuals in Baltimore. • My Sister’s Place Women’s Center, a Catholic Charities program, will support a cook who prepares meals for 85 homeless women and children a day. • Playworks Education Energized, Baltimore will provide safe, healthy and inclusive play to students at low-income schools by preserving recess and making play and physical activity a part of every day. • The Family Tree will launch the Enough Abuse Campaign to prevent child sexual abuse by providing training and prevention messaging to 500 local adults. • Wide Angle Youth Media will provide advanced training in media technology to Baltimore City students ages 14–20 with the objective of enhancing their academic and job-readiness skills. • Writers in Baltimore Schools will provide low-income middle school students with a vibrant environment for literary development through in-school, after-school and summer creative writing workshops. When informed that My Sister’s Place Women’s Center was an award recipient, program manager Valerie Tarantino responded, “When I think of the difference you are helping us to make with this grant, I remember something that St. Francis of Assisi once said: ‘All the darkness of the world cannot extinguish the light of a small candle.’ Thank you for sharing your light with those whose lives have become darkened by poverty and hopelessness.” Rebecca Potter, institutional giving specialist with the Baltimore Symphony Orchestra, said, “Together, we are not only enriching the lives of Baltimore’s urban youth through mentorship and music education, but also we are strengthening wholecommunity potential in East Baltimore by building a strong family, school and neighborhood support network anchored by OrchKids school sites.” Additional information about the Johns Hopkins Neighborhood Fund can be found online at jhu.edu/neighborhoodfund or by contacting the Office of Work, Life and Engagement at 443997-7000.

A D M I N I S T R A T I O N

General counsel Steve Dunham to leave Johns Hopkins

teve Dunham, vice president and general counsel for Johns Hopkins since December 2005, will this summer join The Pennsylvania State University as its vice president and general counsel. “I deeply regret the loss to Johns Hopkins—and to all of us—of such an outstanding colleague, adviser and university citizen,” said President Ronald J. Daniels in a letter last week to university trustees and leadership. “At the same time, however, I am pleased for Steve that he will be able to bring his considerable intelligence, skill and abilities to the service of such an important institution. And I am pleased for Penn State that it has found in Steve an attorney of unparalleled expertise to assist it in dealing with the issues before it.” Daniels described Dunham as “probably the most highly respected university attorney in the United States today.” “At Johns Hopkins,” Daniels said, “he has been invaluable in building a robust system for ensuring compliance with legal requirements in university activities from research, student aid and stewardship of federal dol-

lars to human resources and our expanding international presence. He has contributed significantly to our broadened program of institutional risk management. He has provided important legal support for Johns Hopkins Medicine and been of immense assistance to all Johns Hopkins entities in both crisis management and protection of our institutional reputation.” Before joining Johns Hopkins, Dunham was a Denver-based partner in and former chairman of the global law firm Morrison & Foerster LLP and chief attorney at the University of Minnesota. He has represented colleges and universities, both as in-house counsel and outside attorney, for most of his 43-year legal career, dealing with issues including research, intellectual property, employment, First Amendment freedoms, academic freedom, accreditation, ethics, and appointments and promotions. Plans for interim leadership of Johns Hopkins’ General Counsel’s Office, and a search for Dunham’s successor, will be announced shortly, Daniels said.

4 29,15, 2012 4 THE THE GAZETTE GAZETTE •• May August 2011 After four years at Johns Hopkins, what might be the most appropriate place to say good-bye to college and your friends? The Milton S. Eisenhower Library, where you spent so much of your time, right? Two years ago, a new tradition—with the name MSEE-YA (think about it)—began. It’s a party for seniors set in the stacks and everywhere else, and the dress is definitely not the usual library attire.

Smart idea

WILL KIRK / HOMEWOODPHOTO.JHU.EDU

Study: Molecule necessary for DNA repairs also halts them

epairing DNA breaks can save a cell’s life, but shutting off the repair machinery can be just as critical. How cells accomplish this feat was unknown. However, new research by Johns Hopkins scientists, published in the Feb. 22 issue of Nature, suggests that shutting down the repair machinery relies heavily on the same molecule used to start repair in the first place. According to study leader Cynthia Wolberger, a professor in the Department of Biophysics and Biophysical Chemistry at the Johns Hopkins University School of Medicine, both sides of a DNA strand’s

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double helix can break for a number of reasons, including exposure to ultraviolet light, other kinds of radiation or certain chemicals. These big breaks can be lethal to cells if left unrepaired, or they can cause cancer or other diseases if repairs are shoddily done. Consequently, summoning repair machinery to break sites to quickly and effectively mend these fissures is critical to keeping cells alive and healthy. However, if this repair machinery keeps running after the task is completed, Wolberger explains, it can wreak havoc in a cell by constantly trying to mend breaks that are normal parts of cellular housekeeping and necessary for gene expression. The repair process for double-strand DNA breaks starts when a molecule called ubiquitin—best known for its role in tagging

unneeded proteins for the cellular trash bin— forms chains with the amino acid lysine, which attaches to DNA break sites and serves as a flag to signal repair machinery. A protein called UBC13 is necessary to form these chains. Previous research suggested that a deubiquitinating enzyme called OTUB1 plays an important role in halting chain formation, but unlike other, similar enzymes, it didn’t appear to work by cleaving ubiquitin chains or removing ubiquitin from other proteins. To figure out what’s taking place, Wolberger and her colleagues started with a biochemical analysis of OTUB1. They found that this enzyme contains two different binding sites for ubiquitin: one on a bulky, globular section, and a second on a tail that extends from this globular section. When the researchers used a chemical trick to simulate ubiquitin binding

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Mary Maldarelli, a rising senior at Johns Hopkins, talks with students from DuFief Elementary in Gaithersburg, Md., about the dancing raisin experiment being offered by the Johns Hopkins Center for Biotechnology Education. The students dissolved baking soda in water and then added vinegar, which created carbon dioxide and made their raisins “dance.”

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By Robin Ferrier

Montgomery County Campus

early 800 fourth-graders from seven elementary schools in Montgomery County learned bread baking and, at the same time, basic principles in chemistry, math and measurement, through the King Arthur Flour Life Skills Bread Baking Program, which was held on two days last week on the Johns Hopkins Montgomery County Campus in Rockville, Md.

The day included the bread-baking demonstration plus an hour of hands-on science activities, which were run by representatives of 11 local companies, universities, research labs and federal government entities. The program concluded with students receiving ingredients to make two loaves of bread at home. Each student is supposed to enjoy one loaf with his or her family and bring the second back to school so it can be donated to a nonprofit that helps feed the hungry and homeless in Montgomery County.

in the globular section, tests showed that this binding was necessary to activate OTUB1 to inhibit chain formation. “The real inhibitor isn’t just OTUB1. It’s OTUB1 bound to ubiquitin,” Wolberger explains. Further experiments showed that the second ubiquitin binding site on OTUB1 appears to be meant for ubiquitin carried by UBC13. The researchers found that when OTUB1 forms a complex with UBC13 by attaching to this second ubiquitin, it knocks off a subunit on UBC13 that’s critical for it to function. The researchers’ next step was figuring out how this subunit gets physically removed from UBC13. By working out the 3D structure of activated OTUB1, they found that free ubiquitin bound at the globular site triggers shape changes necessary for OTUB1 to bind to UBC13 by affecting the position of the enzyme’s tail. But when this tail binds to UBC13, its position bumps into another subunit called UEV1a, pushing it off UBC13 completely. Without this subunit, UBC13 can no longer form ubiquitin chains, and without these flags for repair machinery, DNA repairs halt in the cell, Wolberger says. OTUB1 also prevents UBC13 from getting recruited to DNA break sites, further interfering with its activity. Besides solving a cell biology mystery, Wolberger explains, the finding could eventually form the basis for creating drugs that can help cells repair DNA more efficiently after damage. By crafting molecules that bind to OTUB1 or UBC13, researchers might be able to interfere with this normal shut-off process in select situations, keeping DNA-fixing machinery running longer. The finding also suggests that other enzymes in cells, especially those involved with ubiquitin, might have many roles that remain undiscovered. “There are over 100 deubiquitinating enzymes in the genome that we know of,” Wolberger says, “but we still don’t know much about what they do.” This study was funded by the Howard Hughes Medical Institute, National Cancer Institute, National Institute of General Medical Science and U.S. Department of Energy. Other Johns Hopkins researchers on this paper are Reuven Wiener, Xiangbin Zhang and Tao Wang. —Audrey Huang

Related websites Cynthia Wolberger:

biophysics.med.jhmi.edu/wolberger ‘Nature’:

nature.com/nature/index.html

May 29, 2012 • THE GAZETTE

HOMEWOODPHOTO.JHU.EDU

Supergrads Continued from page 1 “I like to think that over the past four years you’ve come to regard Johns Hopkins as a place where avengers thrive, where the ‘us’ triumphs over the ‘I.’ Johns Hopkins is a place where we harness the gifts of our students and faculty, uniting our efforts in the service of our neighborhoods, our nation and our world,” he said. “But the power of the collective is not an idea that is limited to your time at our university. It is an ethos you will carry with you.” Later in his remarks, Daniels issued a charge to the Class of 2012. “Tomorrow, your work begins anew,” he said. “Tomorrow, we place the challenges of our society squarely on your shoulders. And you’re going to have to make that choice, ‘I’ or ‘us.’” Lucas Sand, senior class president, elicited waves of laughter and smiles with his forceful, direct and often deadpan speech to his fellow classmates and their gathered family and friends. He began by photographing the crowd with his camera phone, offering to “tag” anyone on Facebook or tweet them a pic later. He then praised the work of his fellow

senior class leaders, and thanked his family, friends and pizza. “Without those three things, I wouldn’t be here today,” he said to rounds of laughter. “My family has worked hard every day so that I could have whatever it is I want, only for me to graduate and not know what my desires are. Thank you Mom and Dad for your patience, support and money for pizza.” He followed with a gravelly voiced rendition of Vitamin C’s Graduation song before striking a somewhat serious tone. “Let’s give another round of applause to the Class of 2012. Congratulations to everyone.” Sand then introduced the main Commencement speaker, Samuel J. Palmisano, chairman of the board of IBM, a 1973 graduate of Johns Hopkins and a former university trustee. Palmisano, who was awarded an honorary degree during the ceremony, started off by telling those gathered how, “like my friend Luke [Sands],” he didn’t have a clear sense of direction at age 22, but he followed his heart and mind. In his case, he was working construction when a friend told him about a recruiter from IBM coming to campus—in search of women engineers. “I told him I didn’t know if I’d fit,” he joked. “But I thought figures were better than digging ditches, so I applied and got the job.” He would go on to a 40-year career

with the global IT giant, rising to the top rung of leadership. Palmisano brought up the challenges that lay before the current generation in terms of a tepid economic environment, unemployment and global conflicts. Yet, despite these challenges, he told the graduates, a new golden age of economic growth, scientific discovery and social progress approaches. In this data-driven information age, he said, success will go to the bold who want to remake the world for the better. “I think the most powerful asset that you acquired at Johns Hopkins goes beyond skill and expertise; it is the impulse and power to seize the moment,” he said. He ended his talk with a piece of advice for the graduates. “Don’t limit your options,” he said. “Do not constrain yourself. Reach out and go for it.” Also awarded honorary degrees on Thursday were Rita R. Colwell, an environmental microbiologist and worldwide leader in the fight to provide safe drinking water; Stephen H. Lewis, a Canadian diplomat, politician, broadcaster and academic dedicated to humanitarian service; John C. Malone, chair of Liberty Media and of Liberty Global, which provides broadband distribution and video programming in Europe, Latin America and Australia; Amartya Sen, an economist celebrated for his trailblazing studies of social

choice, welfare measurement and poverty; and Daw Aung San Suu Kyi, revered around the world for her peaceful fight for democracy in Burma. In an unusual move, Aung San Suu Kyi’s degree was presented in absentia, and she accepted it in a video message. Following the ceremony, graduates and families found each other—thousands of them at the President’s Reception on the Keyser Quadrangle—to exchange hugs, tears and high-fives. The graduates expressed mixed emotions of realizing that one journey ends and a new one begins. Cynthia Idada was greeted after the ceremony by her large family contingent, all wearing T-shirts with her picture and words of congratulations on them. Idada, a public health studies major, said that the moment was a bit overwhelming. “I couldn’t have done it without my family. Going through all the trials that I went through at Johns Hopkins, it’s really important to have my family here,” she said. “I can’t believe it’s over, but I’m excited because I’ll be here next year doing something different. I’m going to be a grad assistant with the [Office of Residential Life] and trying to get my master’s in environmental health sciences at the School of Public Health. So, a new chapter begins.” A new chapter for the entire Class of 2012 awaits. G

6 29,15, 2012 6 THE THE GAZETTE GAZETTE •• May August 2011 H U M A N

B U L L E T I N

R E S O U R C E S

Notices

Hot Jobs

No notices were submitted for publication this week.

Listed below are some of the university’s newest openings for in-demand jobs that we most urgently need to fill. In addition to considering these opportunities, candidates are invited to search a complete listing of openings and apply for positions online at jobs.jhu.edu.

Genes at fault for cystic fibrosis– related intestinal obstruction By Michelle Jones

Homewood

Johns Hopkins Medicine

Office of Human Resources Wyman Park Building, Suite W600 410-516-7196 The Development and Alumni Relations communications organization is seeking a Director of Communications and Marketing to lead the developing marketing and communications strategies and content in all media that will advance the strategic goals of Development and Alumni Relations programs, especially the capital campaign. For a detailed job description and to apply, go to jobs.jhu.edu. 52513

Director of Communications and Marketing

School of Medicine Office of Human Resources 98 N. Broadway, Suite 300 410-955-2990 The School of Medicine has a part-time opportunity for someone seeking exposure to administrative service experience in a scientific research environment. The successful applicant will report to the director of the Lowe Family Genomics Core, a multifunctional genomics facility located on the Bayview campus. For a detailed job description and to apply, go to jobs.jhu.edu. 51369

Laboratory Coordinator

Schools of Public Health and Nursing Office of Human Resources 2021 E. Monument St. 410-955-3006 The Bloomberg School of Public Health is seeking skilled applicants for several partand full-time positions. For detailed job descriptions and to apply, go to jobs.jhu.edu. 49102 Programmer Analyst 50518 Senior Programmer Analyst 50994 Senior Research Program Coordinator 51307 Biostatistician 51437 Research Data Analyst 51690 Research Technologist 52128 Research Program Manager 52201 Clinical Placement Coordinator 52258 Senior Programmer Analyst 52305 Clinical Research Program Coordinator 52377 Program Administrator

Johns Hopkins University is an equal opportunity employer and does not discriminate on the basis of gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, other legally protected characteristics or any other occupationally irrelevant criteria.

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esearchers at Johns Hopkins have identified a gene that modifies the risk of newborns with cystic fibrosis developing neonatal intestinal obstruction, a potentially lethal complication of the disease. Their findings, which appeared online March 15 in PlosGenetics, along with the findings of their Toronto-based colleagues, published April 1 in Nature Genetics, may lead to a better understanding of how the intestines work and pave the way for identifying genes involved in secondary complications of other disorders. Soon after birth, most babies excrete their first stool, a tarlike substance called meconium, but not babies with neonatal intestinal obstruction, or meconium ileus, which affects 15 percent of newborns with cystic fibrosis and, rarely, newborns without cystic fibrosis. Their stool is different. “It is abnormally viscous due to high protein content and low levels of hydration, and the child can’t move it through the intestine,” said Garry Cutting, a professor of pediatrics at Johns Hopkins’ McKusickNathans Institute of Genetic Medicine. The condition results in death if not treated by surgery or enema. But why some newborns with cystic fibrosis, or CF, get it and others don’t is not well understood. To better understand why this is so and to develop models for finding so-called modifier genes—genes that modify the effects of other genes—Cutting and his colleagues aimed to figure out which modifier genes contribute to the development of meconium ileus, or MI. (From their previous work, they already knew that modifier genes contribute to its development.) Working with Toronto-based collaborators, members of Cutting’s team looked for gene variants that occur in CF patients with MI. They knew that CF is caused by disruption of the CFTR gene, which encodes for a cell membrane protein, so they thought that the genes that alter CFTR’s activity and cause MI might also encode for cell membrane proteins; after all, a cell membrane protein is more likely to interact with a nearby cell membrane protein than with a protein that’s deep inside the cell. The researchers tested DNA samples from 3,763 CF patients—611 who had had MI and 3,152 who hadn’t—to compare genes that encode for cell membrane proteins to those that encode for unrelated proteins. Three of the 155 genes tested that encode for cell membrane proteins correlated with risk for MI, compared with none of the 231 genes tested that encode for unrelated proteins. “These genes have common variants that all of us happen to be carrying around,” Cutting said, “and just by chance, if you have a child with CF, these common variants play a role in modifying risk for meconium ileus.” The researchers wanted to look for additional gene variants associated with an increased risk for MI, using a different approach. In an earlier study, Cutting’s team had found a region of human chromosome 8 to

GIVE BLOOD. For information, go to hopkinsworklife.org/community/ blood_drive_locations.html

be linked to MI. To pinpoint which gene within that region leads to the condition, the researchers analyzed the DNA of 133 families with two or more CF children, at least one of whom previously had MI. The DNA was tested to determine which parts of chromosome 8 parents had passed down to their children who had MI. Using this approach, the researchers found variants of the methionine sulfoxide reductase, or MSRA, gene—in this case, a particular combination of DNA alterations close to and within the gene—that appeared significantly more often in children who had MI. In an unrelated CF patient population from Canada, they found evidence of the same link between MSRA and MI, which helped confirm their results. While the researchers now knew that CF patients with a certain MSRA gene variant tended to have had MI as newborns, they didn’t yet know whether MSRA actually plays a role in MI and therefore whether it is truly a modifier gene. To address this question, they turned to mice engineered to have CF that tend to die from intestinal obstruction and developed three genetically modified versions of these mice: one with both MSRA genes intact, one with only one intact and one with none intact. The fewer the copies of intact MSRA genes, the more likely the mice were to survive. In other words, the loss of MSRA protected the mice from fatal intestinal obstruction. Cutting and his colleagues don’t know exactly how the loss of MSRA reduces risk for fatal intestinal obstruction, but they suspect that MSRA’s ability to alter the activity of specific intestinal enzymes may be the key. They surmise that with reduced levels of MSRA, the enzymes are free to do their job breaking down proteins that make up meconium so that it can pass through the intestines and be evacuated normally at birth. The researchers’ work on MSRA could shed light on how meconium normally gets broken down in the intestines. Moreover, use of the techniques pioneered by Cutting and his colleagues may lead to identification of modifier genes that play roles in other complications of CF, such as lung function, and in other diseases caused by a single gene, such as Huntington’s disease. The studies were funded by the National Heart, Lung and Blood Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, and the Cystic Fibrosis Foundation. Authors on both the Plos Genetics and Nature Genetics papers from Johns Hopkins are Lindsay B. Henderson, Vishal K. Doshi, Scott M. Blackman, Kathleen M. Naughton and Cutting.

Related websites McKusick-Nathans Institute of Genetic Medicine:

hopkinsmedicine.org/ geneticmedicine Gary Cutting:

www.hopkinsmedicine.org/ geneticmedicine/People/Faculty/ cutting.html ‘Plos Genetics’:

plosgenetics.org/home.action ‘Nature Genetics’:

nature.com/ng/index.html

May 29, 2012 • THE GAZETTE

Classifieds APARTMENTS/HOUSES FOR RENT Assateague Pointe, 2BR house in gated community, 2 swimming pools, fishing pier, biking, birding, quiet place for friends/family, 5 mi to Ocean City and Assateague National Seashore, avail wkly year-round. $950/wk. Claire, 410-908-5286 or cjh3219@msn.com. Butchers Hill, beautifully remodeled 3-story house, 3 BR suites, 3.5BAs, kitchen, W/D, dw, sec sys, amazing rooftop deck, avail July 1. $2,495/mo. Sharon, 443-695-9073.

M A R K E T P L A C E

Mt Washington, lg, modern 2-story TH, 3BRs, 2.5 remodeled BAs, CAC, dw, W/D, hdwd flrs, lg storage space, backyd, deck, covered prkng, walk to swimming pool/schools, easy commute to JHU/JHH/downtown by car, light rail or subway, Mt Washington school district. $1,875/ mo + utils. kistennolan@gmail.com. Mt Washington, spacious 4BR house, 2.5BAs, furn’d, CAC, ideal for family on academic sabbatical, avail Aug 20, 2012, to Aug 30, 2013. $2,800/mo. 410-466-0255 or b.meneveau@ comcast.net.

Gardenville, 3BR, 1.25BA RH in a quiet neighborhood, 15 mins to JHH, new kitchen and BA, CAC, hdwd flrs, fenced, maintenancefree yd w/carport, club bsmt w/cedar closet. $105,000. 443-610-0236 or tziporachai@ juno.com. Homeland, fabulous, totally renov’d Tudor house. 410-812-2423 (for an appt) or 5200springlakeway.com. Mt Washington, 4BR, 3.5BA TH, landscaped, easy access to 83/695/lt rail. $289,000 ($5,000 toward closing). lisamwolf@comcast.net. Towson/Stoneleigh (18 Stoneridge), 3BR, 2.5BA TH, updated kitchen and BAs, deck, community pool. $264,800. 330-310-5340 or nancyhofmann.com. 3402 Mt Pleasant Ave (21224), completely rehabbed and superb quality. $159,900. jvgiiird@hotmail.com.

Charles Village, 3BR, 2BA Victorian RH, W/D, sec sys, fenced yd, garage, 5-min walk to shuttle, no pets/no smokers. $1,650/mo + utils. 301-699-7583 or housecv@gmail.com.

Mt Washington, quiet, spacious 4BR, 2.5BA house, avail June 11-Aug 5, W/D, hdwd flrs, WiFi, grand piano, no smoking/no pets. $1,975/ mo incl utils. 410-913-9687 or violaine62@ comcast.net.

Charles Village, 2- to 3BR, 2BA house, new kitchen and new BAs, laundry, prkng, 2 blks to shuttle, 3 blks to campus. 410-383-2876 or atoll4u@gmail.com.

Ocean City, MD (137th St), ocean block, 3BR, 2BA condo, lg in-ground pool, steps from beach, off-street prkng (2 spaces), short walk to restaurants and entertainment. 410-544-2814.

1.5BR, 1BA in lovely, furn’d TH in safe Homeland community w/pool, owner has adorable retriever. $1,000/mo + utils. camel_pondyland@ yahoo.com.

Charles Village, 1BR in historic RH, sunny kitchen, AC, W/D, bsmt storage, porch swing, Internet, nr shuttle, avail July 1. $925/mo (unfurn’d) or $975/mo (furn’d). 410-236-9840.

Parkville, cozy 1BR, 1BA lower level apt, AC/ heat/cable, kitchen, W/D, priv entry, great yd, just renov’d, avail June 1. $900/mo. 443-7567071.

Charles Village, 2BR, 2BA apt in renov’d, historic Telephone Bldg (31st and Guilford), loftlike space, bamboo flrs, granite counters, stainless steel appls, W/D, CAC, intercom sec sys, bsmt gym/storage bin. $2,100/mo. 917941-1365 or pgelston@gmail.com.

Rehoboth Beach, 3BR TH, 15-min walk to beach, dog-friendly, weekly rentals, JHU discounts for summer 2012. galeeena@yahoo.com.

Two wanted to share 4BR, 3BA TH in Upper Canton (21224), 1 blk from the park, one rm has BA in it, second rm has BA next to it, ample prkng, great social events. 443-2261274 or courtmarie54@gmail.com.

Deep Creek Lake/Wisp, cozy 2BR cabin w/full kitchen; call for wkly/wknd rentals. 410-6389417 or jzpics@yahoo.com (for pics). Ellicott City, 4BR, 2.5BA single-family house, 3,400 sq ft, 3.5 acres, great neighborhood w/ excel school district, beautiful stream in rear of property, all maintenance covered, 1-yr lease, no pets. $2,800/mo. Jason, 410-531-1500. Evergreen/Roland Park, 3BR, 2BA house, 15-min walk to Roland Park Elementary, photos avail. $2,900/mo (negotiable depending on whether house is rented furn’d/unfurn’d). 410-520-6264. Fells Point, 1BR, 1BA apt, AC, ceramic tile in BA, hdwd flrs, appls, outdoor roof deck, pref nonsmoker. $1,000/mo + utils. 410-375-4862. Guilford, spacious 4BR, 2BA TH, bsmt, living rm, dining rm, back alley prkng space, front and back porch, W/D. $1,400/mo. 443-6915110. Hampden, efficiency apt on 41st St, 2 lg closets, crpt, tile, shared laundry area. $700/mo. Steve, 443-474-1492 or steverutz.com/apt.htm (pics avail). Hampden (Falls Rd and Morling Ave), lovely 3BR duplex, close to everything, 2,000 sq ft, 2 full BAs, spacious eat-in kitchen, dw, W/D, lots of free on- and off-street prkng, 1-yr lease, sec dep req’d. $1,500/mo. Mina, 410-592-2670. Hampden/Medfield Heights, beautiful house on quiet street, nr JHU/I-83, avail Sept 1. 410733-6231. Homeland, 2BR, 2BA in quiet bldg, gated community, updated kitchen, CAC, W/D in unit, swimming pool, exercise rm. $1,200/mo incl heat, hot water. 410-878-2315 or drew@ mcproperty.com.

Waverly, 2BR+, 1BA RH in family neighborhood, open flr plan on lower level w/deck off kitchen, dw, W/D, walkout bsmt to backyd and deck, nr Homewood/grocery/farmer’s market/ YMCA/public transportation, avail June 15, summer lease or full yr avail. $1,200/mo + utils. 315-824-3646 or stefanie.fishel@gmail.com. White Marsh, 3BR, 2.5BA TH condo, great location mins from I-95/White Marsh Town Center/restaurants/shops, prkng space. $1,375/ mo. 410-662-2388 or yuan23q@gmail.com.

Summer sublet: spacious studio, modern stainless steel appls, lots of light, big windows, balcony, on-site pool, gym, security card access, avail June 1-Aug 31 (dates flexible). $930/mo incl utils. 410-929-2703. Sublet huge 2BR, 2.5BA apt w/loft, avail June and July, W/D in unit, fully equipped kitchen, MTA and light rail stop in front of bldg, 5-min walk to JHU shuttle or Charm City Circulator (purple line) stop at Washington Monument. $600/mo. 785-550-0929 or pianistsong@ hotmail.com. Very spacious 3- and 4BR apts nr Homewood campus, avail for summer/fall occupancy. $1,395/mo or $1,495/mo. 443-253-2113 or pulimood@aol.com.

410.764.7776

www.brooksmanagementcompany.com

age ottoman, $15; used only 8 months, 443455-2302 or yamilquevedo@gmail.com. Metal 2-drawer file cabinets (2), $10. 443-8041927 or adesantiswhitaker@gmail.com. Coffee tables: butler’s table-style, cherry, $20; new bamboo oval table w/glass top, $30. Best offers, cash only. 410-207-2217. Moving sale: dining set, table w/4 chairs, $250; sofa, $350; chair, $75; coffee table and side tables, $50/all; queen size bed, boxspring, mattress, $350; dresser w/mirror, $200; nightstand, $25; TV stand, $25; lamps (4), $10/ea. 217721-4379 or rovvves@gmail.com. Portable canvas patio chair, Epson Stylus 760 color printer, sand beach chairs (2), Roland digital piano, 100W amplifier, keyboard case, oilfilled heaters (3), ergonomic kneeling posture chair. 410-455-5858 or iricse.its@verizon.net. Kitchen supplies, dishware, dining rm set, exterior French doors, full-length silver fox coat, fitness chair, masonry/wood sprayer, garden mesh, man’s travel bag, champagne buckets, Fossil watch boxes, Playboy mags. 443-8242198 or saleschick2011@hotmail.com. Antique gooseneck rocker, mahogany w/ dark green tweed, $40; Hoover Legacy vacuum, strong suction, long cord, lg bag, $25. johannecoll@hotmail.com.

SERVICES/ITEMS OFFERED OR WANTED Would you like to play indoor tennis this summer on a Johns Hopkins team? Tuesday evenings, June through Aug, men’s, women’s and mixed doubles, approx 3.0-4.0 level. Peter Barker, pbbark@gmail.com. Dog-walking and house-sitting service, reliable, clean, nonsmoker. Lynn, 410-877-6165.

F wanted to share new 3BR, 3.5BA TH, 2 blks to JHMI. $540/mo + utils. 410-979-0721 or grant.tz@comcast.net.

Earn $6,000/mo working from home, join team of young college grads and start home-based business. 443-826-9830.

F wanted for peaceful, furn’d 3BR, 2BA house, short-term lease OK. $600/mo incl wireless, utils, prkng. skbzok@verizon.net.

JHU grad student tutor for physics/math/chemistry, elementary to high school, will tutor on JHU campus. 410-402-3303 (9am-9pm) or helena.tutoring@gmail.com.

’03 Ford Excursion Limited, black w/tan leather interior, 4WD, 123K mi, in good cond. $6,000. 443-850-4338.

’89 Toyota Tercel, 4-spd, 71K mi, qualifies for antique tag, no inspection req’d. $1,250. 443750-7750.

ITEMS FOR SALE Brown leather loveseat, $400; lg, cream-colored leather sofa and loveseat set, tables not incl’d, $850; wood coffee table, $50; all in very good cond. 410-913-0805 or jrichard7@ verizon.net. Dining rm set, table seats 6, 5 matching chairs; set is small enough for an apt but large enough for games and activities. $100/all. 317-2252062. Apple Power Mac G5 2.3 DP, model# M9748LL/A, release early 2005 (ID 7,3), OS X 10.4, keyboard and monitor, disks incl’d, 1GB memory, 250GB hard drive. $275. aweil@ baitman.org. Sofabed, $40; dinner table set, 5 pcs, $45; stor-

Interested in Web development, data analytics or electronics? Accepting summer volunteer applications at JHU Eastern’s Emerging Technology Center. info@graphtrack.com. Grass cutting, weed whacking, edging, leaf removal and exterior painting and junk hauling. George, 443-762-3183. Landscaper/certified horticulturist avail to maintain existing gardens, also designing, planting or masonry; free consultations. David, 410-683-7373 or grogan.family@hotmail.com. Editing of biomedical documents offered by a PhD biomedical scientist and certified editor in the life sciences. 443-600-2264 or michellejones@jonesbiomediting.com. Masterpiece Landscaping provides knowledgable on-site consultation, transplanting, bed prep, installation, sm tree/shrub shaping, licensed. Terry, 410-652-3446. Licensed landscaper avail for spring/summer lawn maintenance, mulching, yard cleanup, other services incl’d trash hauling. 410-8126090 or romilacapers@comcast.net. Hauling/junk removal, next-day pickup possible, free phone estimate ($40 and up), 15% discount all JHU. John, 410-419-3902.

HOUSES FOR SALE

Fells Point, 3-story RH in historic district, lg priv yd, many recent renovations. Dorothy, 443-750-7750.

with Balcony - $790

Rm avail in updated Fells Point house, share w/2 housemates, priv patio. $660/mo incl BGE, dish, Internet. ryanwhiggins@gmail.com.

Wyman Park, newly furn’d 1BR apt, very spacious, luminous, living rm, kitchen, park across the street, 10-min walk to Homewood campus, avail June 6-Aug 17. 443-509-2263 or saelam86@gmail.com.

Middle River, lg, private apt, 1.5BRs and full BA, CAC, W/D, cable/Internet, 20 mins to JHMI, utils incl’d. 410-292-0669.

Shown by appointment

F wanted for lg, furn’d BR and priv BA, nr JHH/SoN/SPH (max 10-min walk), very good view, high-speed Internet. $650/mo + utils. myhome.2011@yahoo.com.

CARS FOR SALE

Bayview, 2BR, 2BA EOG, 1,400 sq ft, bright rms, newly renov’d, new appls, granite, lg upstairs laundry, office or 3rd BR, washer on fin’d lower level. $158,000. 410-935-8060.

A lovely hilltop setting on Hickory Avenue in Hampden! 2 BD units from $760

ROOMMATES WANTED

Wyman Park, 5BR, 2.5BA RH in safe area, 3 stories, new W/D, new stainless steel appls, window AC units supplied/installed, pet allowed w/ fee, no smoking, 1-yr lease, move in July 1 (flexible), nr Rotunda/shuttle stop, across from JHU Keswick Bldg. $2,400/mo. 410-234-9282.

Mayfield, charming 3BR, 2BA house, hdwd flrs, fp, garage, yd/patio, nr Homewood/JHH/ Bayview. $1,750/mo. 410-852-1865 or miriam .mintzer@gmail.com.

HICKORY HEIGHTS

Use The Gazette Classified Ads online submission form jhu.edu/gazette/adform.html

PLACING ADS Classified listings are a free service for current, full-time Hopkins faculty, staff and students only. Ads should adhere to these general guidelines: • One ad per person per week. A new request must be submitted for each issue. • Ads are limited to 20 words, including phone, fax and e-mail.

• We cannot use Johns Hopkins business phone numbers or e-mail addresses. • Submissions will be condensed at the editor’s discretion. • Deadline is at noon Monday, one week prior to the edition in which the ad is to be run. • Real estate listings may be offered only by a Hopkins-affiliated seller not by Realtors or Agents.

(Boxed ads in this section are paid advertisements.) Classified ads may be faxed to 443-287-9920; e-mailed in the body of a message (no attachments) to gazads@jhu.edu; or mailed to Gazette Classifieds, Suite 540, 901 S. Bond St., Baltimore, MD 21231. To purchase a boxed display ad, contact the Gazelle Group at 443-275-2687.

8 THE GAZETTE • May 29, 2012 M A Y

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Calendar

B L OO D D R I V E S

Wed., May 30, 8:30 a.m. to 2 p.m. JHU/American Red Cross

blood drive. For more information, call 410-614-0913 or email johnshopkinsblooddrive@jhmi .edu. Johns Hopkins@Eastern.

Dean’s Lecture—“Hopkins in Malaysia: PUGSOM Turns 1” by Charles Wiener, dean/CEO, Perdana University Graduate School of Medicine and SoM. Sponsored by the Dean’s Office. Hurd Hall. EB

S E M I N AR S COLLOQUIA

“Galaxy Formation and Evolution Through Metals,” an STScI colloquium with Lisa Kewley, University of Hawaii. Bahcall Auditorium, Muller Bldg. HW

Wed., May 30, 3:30 p.m.

The AsianPacific-American Heritage Colloquium—“The Department of Energy” with U.S. Secretary of Energy Steven Chu. Sponsored by the Applied Physics Laboratory. Parsons Auditorium. APL

Fri., June 1, 2 p.m.

DISCUSSIONS/ TALKS

Wed., May 30, 10 a.m. “Using Budding Yeast to Establish Principles of Cell Fate Regulation,” a Biomedical Engineering faculty candidate seminar with Andreas Doncic, Stanford University. 709 Traylor. EB (Videoconferenced to 110 Clark. HW )

“Phenotype-Optimized Sequence Ensembles Substantially Improve Prediction of Disease-Causing Mutation in Cystic Fibrosis,” a Physiology seminar with Rachel Karchin, WSE. 203 Physiology. EB

L E C T URE S

“BlackWhite Disparities in Overweight/ Obesity Trends and ObesityRelated Mortality in the United States,” an Epidemiology thesis defense seminar with Chandra Jackson. W1214 SPH. EB

Wed., May 30, 1 p.m. “Quantitative and Mixed Methods Studies of Mood Disorders and Mental Health Service Use Among Asian-Americans,” a Mental Health thesis defense seminar with Su Yeon Lee. 208 Hampton House. EB

“GasLiquid Multiphase Flows for High Wed., May 30, 3 p.m.

Wed., May 30, 3 p.m.

Special

“Discovery of Orexin Antagonists for the Treatment of Sleep Disorders,” a Pharmacology and Molecular Sciences seminar with Paul Coleman, Merck Research Laboratories. West Lecture Hall (ground floor), WBSB. EB

Wed., May 30, 4 p.m.

“Cytoskeletal Control of Epidermal Development,” a Cell Biology seminar with Terry Lechler, Duke University Medical School. Suite 2-200, 1830 Bldg. EB

“Structure and Dynamics of GPCR Rhodopsin,” a Biological Chemistry seminar with Oliver Ernst, University of Toronto. 612 Physiology. EB

Tues., June 5, noon.

“SUMO ylation: From Mechanisms to Diseases,” a Molecular Pathology seminar with Edward Yeh, University of Texas: MD Anderson Cancer Center. Sponsored by Pathology. G-01 BRB. EB Wed., June 6, noon.

Thurs., May 31, noon.

Wed., May 30, noon.

Fri., May 25, 10 a.m. “The Kosovo and Serbian Elections: An OSCE Success,” a SAIS Center for Transatlantic Relations discussion with Edward Joseph, Organization for Security and Cooperation in Europe Mission in Kosovo. For information or to RSVP, go to eventbrite.com/event/ 3583372965. 500 Bernstein-Offit Bldg. SAIS

Speed Microfluidics,” a CEAFM special seminar with Carlos Hidrovo, University of Texas, Austin. 50 Gilman. HW

The David Bodian Seminar—“Why Don’t Rodents Play the Violin? Evolution in the Neural Substrate of Motor Skills” with Peter Strick, University of Pittsburgh. Sponsored by the Krieger Mind/Brain Institute. 338 Krieger. HW

Mon., June 4, 4 p.m.

Thurs., May 31, 12:30 p.m.

“Published Reports Describing Clinical Trials in Off-Label Uses of Drugs: Are They a Valid Source of Knowledge,” an Epidemiology thesis defense seminar with Swaroop Vedula. W1214 SPH. EB Mon., June 4, 11 a.m. “Activity-Dependent Circuit Assembly in the Developing Brain: From Axon Targeting to Dendrite Pruning,” a Krieger Mind/Brain Institute special seminar with Chunlei Wang, Georgia Health Sciences University. 338 Krieger. HW Mon., June 4, 2 p.m. “Analyzing the Performance of a Trauma Team Activation Tool Used at a Level I Pediatric Trauma Center,” a Health Policy and Management thesis defense seminar with Rosemary Nabaweesi. 688 Hampton House. EB

SPECIAL EVENTS

Thurs., May 31, 5:30 to 8 p.m.

2012 Asian American and Pacific Islander Heritage Month Celebration, with Washington D.C. Mayor Vincent Gray. A networking reception will precede the event at 5:30 p.m. The official program will begin at 6 p.m. A live webcast of the event will be available at sais-jhu.edu/pressroom/ live.html. Sponsored by SAIS and the Washington D.C. Mayor’s Office. For more information or to RSVP, go to may31aapi.eventbrite .com. Kenney Auditorium, Nitze Bldg. SAIS Sat., June 2, 11 a.m. to 9 p.m., and Sun., June 3, 11 a.m. to 6 p.m. Charles Village Festival,

with live entertainment on two stages, kids’ activities, crafters and beer/wine and food vendors, and a neighborhood garden walk. (See In Brief, p. 2.) Wyman Park Dell, Charles and 29th Streets. Thurs., June 7, 6 to 8 p.m.

An Evening of Traditional Beverages—Punch! with Corey Polyo-

ka, chief mixologist, Woodberry Kitchen. (See In Brief, p. 2.) $35 for Homewood Museum members, $45 for nonmembers (must be 21 or over). Space is limited and registration is requested by June 1; go to brownpapertickets .com/event/171923 or call 410516-5589. Homewood Museum lawn (rain location: Glass Pavilion, Levering). HW W OR K S H O P S The Center for Educational Resources sponsors a series

of hands-on workshops on the Blackboard interface. The training is open to all faculty, students and staff who have administrative responsibilities in a Blackboard course. Seating is limited to six per session. To register, go to bb.cer.jhu.edu. Garrett Room, MSE Library. HW •

Mon., June 4, 2:30 p.m.

•

Tues.,

•

Wed.,

“Getting Started.” June

a.m.

“Communication and Collaboration.” June

a.m.

“Assessment and Grades.”

(Events are free and Calendar open to the public Key except where indicated.) APL BRB CRB EB HW JHOC

Applied Physics Laboratory Broadway Research Building Cancer Research Building East Baltimore Homewood Johns Hopkins Outpatient Center KSAS Krieger School of Arts and Sciences NEB New Engineering Building PCTB Preclinical Teaching Building SAIS School of Advanced International Studies SoM School of Medicine SoN School of Nursing SPH School of Public Health WBSB Wood Basic Science Building WSE Whiting School of Engineering

One in three households misreports smoke alarm coverage tracts in eastern Baltimore, a relatively lowincome urban area. After respondents completed the questions on fire-safety behaviors, data collectors tested the functionality of all smoke alarms in the house. A small sample of the overreporters were contacted by phone and asked a series of questions aimed at better understanding reasons for overreporting. “Despite the small number of followup respondents, the phone interviews give us some important insights,’’ said Andrea Gielen, director of the Johns Hopkins Center for Injury Research and Policy and senior author of the report. ‘‘Particularly troubling is the fact that one in three of the follow-up respondents indicated they reported greater coverage than they actually had because they knew they should.’’ This social desirability bias occurred despite the fact that respondents had been informed that data collectors would be testing alarms in the home as part of the interview. ‘‘The implication for both researchers who survey residents and firefighters who canvass communities is that it’s critical to confirm smoke alarm status with actual testing of the alarms,’’ Gielen said. In conclusion, Shields said, ‘‘Given the huge public health toll of residential fires in the U.S., every effort should be made to keep people safe in their homes. Public education efforts should include specific instructions on how to check alarm functionality and on the importance of having an alarm on every level of the house. More widespread use of the new 10-year lithium

battery alarms would also make it easier for residents to keep their homes and families protected,’’ she said. Additional authors of the study are Rebecca Stepnitz and Eileen McDonald, both of Johns Hopkins. Support for this research was provided

to the Johns Hopkins Center for Injury Research and Policy by grants from the National Center for Injury Prevention and Control at the Centers for Disease Control and Prevention, and the National Institute of Child Health and Human Development. —Alicia Samuels

CHUCK BECKMAN / CTY

ne in three households in Baltimore misreports its smoke alarm coverage, with the vast majority of errors due to overreporting it, according to a study by researchers from the Johns Hopkins Center for Injury Research and Policy. Reasons for overreporting included study participants’ incorrectly assuming that all their alarms were working because they weren’t beeping, and not having alarms on every level of the home. Previous research has found varying validity for self-reporting of smoke alarm coverage, but this study is unique for also examining the reasons why individuals misreport. The study is available online in advance of publication in the journal Injury Prevention. “Forty percent of all residential fire deaths in the U.S. occur in homes with no smoke alarms, and another 23 percent occur in homes where an alarm is present but not functioning,’’ said study author Wendy Shields, an assistant scientist with the Center for Injury Research and Policy, part of the university’s Bloomberg School of Public Health. ‘‘Our study suggests relying upon self-reports of smoke alarm coverage is not an accurate way to measure whether homes are protected.’’ The National Fire Protection Association recommends that all residential homes have a smoke alarm in every bedroom, outside every sleeping area and on every level of the home. Shields and colleagues conducted interviews and home observations in more than 600 households selected from 12 census

A BIG SHAKE: Showing sportsmanship by shaking hands before their chess match are Brandon Boles, a pre-K student at Pimlico Elementary, and Jaylon Simpson, a first-grader at Alexander Hamilton Elementary. The duo competed in the citywide chess tournament held May 22 in Homewood’s Glass Pavilion. Simpson finished the day undefeated and was crowned the Baltimore Kids Chess League first-grade chess champion. Johns Hopkins’ Center for Talented Youth sponsors the annual event, which drew 125 students from 35 city schools. —Chuck Beckman