Biopharmaceuticals market

Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020

Persistence Market Research

Global Biopharmaceuticals Market Will Reach US$ 278 Bn by 2020:Persistence Market Research

Persistence Market Research

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 Persistence Market Research Released New Market Report “Global Market Study on Biopharmaceuticals:

Asia

to

Witness

Highest

Growth

by

2020”, the global

biopharmaceuticals market was valued at US$ 162 Bn in 2014 and is expected to grow at a CAGR of 9.4% from 2014 to 2020, to reach an estimated value of US$ 278 Bn by 2020.

Browse the full report at :http://www.persistencemarketresearch.com/marketresearch/biopharmaceutical-market.asp

Biopharmaceuticals are medicinal drugs, produced by isolation of the medicinal products from biological sources such as from animals, plants, humans and microorganisms, using biotechnological techniques such as recombinant DNA technology. They can also be produced using transgenic organisms, particularly animals and plants that have been genetically engineered to produce drugs. These drugs help in prevention and treatment of various diseases such as rheumatoid arthritis, psoriatic arthritis, psoriasis, cardiovascular disease, anemia arising from chemotherapy, chronic renal failure, cancer, and diabetes.

Globally, the biopharmaceuticals market is witnessing significant growth due to increasing prevalence of chronic diseases, rising aging population, technological advancements in biopharmaceuticals, and increasing R&D investments. In addition, the capability of biopharmaceuticals to approach a particular target with high efficacy helps in the treatment of various chronic diseases and disorders. Biopharmaceuticals, such as monoclonal antibodies,

hormones,

cytokines,

clotting

factors,

cell

therapies,

antisense

drugs,

recombinant insulin, and vaccines, have the potential to prevent, treat, and completely heal the diseases which are otherwise difficult to cure or have no available treatment. This, in turn, fuels growth of the biopharmaceuticals market. However, factors such as high costs of biopharmaceuticals, the risk of side–effects, and availability of low-cost biosimilars are restraining

the

growth

of

the

global

market

for

biopharmaceuticals.

The

global

biopharmaceuticals market was valued at US$ 162 Bn in 2014 and is expected to reach US$ 278 Bn by 2020 at a CAGR of 9.4% during the forecast period.

North America is the largest market for biopharmaceuticals. This is due to technological advancements in the region. The North America market for biopharmaceuticals was valued at US$ 64.7 Bn in 2014 and is expected to reach US$ 111.5 Bn by 2020 at a CAGR of 9.5%

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 over the forecast period. In terms of type, monoclonal antibodies are the fastest growing segment. In terms of therapeutic application, oncology is the largest segment in the biopharmaceuticals

market.

Biopharmaceuticals

have

wide

applications

in

the

pharmaceutical industry.

One of the latest trends in the global biopharmaceuticals market is that of outsourcing, where

biopharmaceutical

companies

are

dependent

on

contract

manufacturing

organizations to produce a biopharmaceutical drug substance, which helps reducing investments for a new product launch.

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Sample

Report

at

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Pfizer, Inc., F. Hoffmann-La Roche AG, Johnson & Johnson Services, Inc., Sanofi, Amgen Inc., AbbVie Inc., Merck & Co., Inc., Biogen Idec, Bayer AG, Eli Lilly and Company, and Novartis AG are leading players in the global biopharmaceuticals market. Some of the other players in the biopharmaceuticals market are GlaxoSmithKline Plc, Bristol-Myers Squibb Company, AstraZeneca PLC, and Abbott Laboratories.

The biopharmaceuticals market is segmented as follows:

By Type •

Monoclonal antibodies

•

Erythropoietin

•

Granulocyte-colony stimulating factor (G-CSF)

•

Purified proteins

•

Recombinant proteins

•

Recombinant human insulin

•

Growth hormones

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020

•

Interferon

•

Vaccines

•

Others

By Therapeutic applications •

Metabolic disorders

•

Oncology

•

Neurological disorders

•

Cardiovascular diseases

•

Inflammatory and infectious diseases

•

Others

By Geography North America •

The U.S

•

Canada

Europe •

The U.K.

•

Germany

•

France

•

Italy

•

Spain

•

Russia

Asia •

Japan

•

China

•

India

Rest of the World

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020

•

Brazil

•

Australia

Market History: Biopharmaceuticals are pharmaceutical products which are produced through biotechnology methods involving

recombinant

DNA

techniques,

hybridoma

techniques,

and

purification

processes.

Biopharmaceutical production involves the use of biological sources, either live organisms or their active components. They are made up of proteins and nucleic acids and target specific diseases and patients groups. Biopharmaceuticals are used in the treatment of various chronic diseases such as cardiovascular, metabolic, neurological, cancer, and other rare diseases for which there are no available treatments. It has lead to enhancement of the quality of healthcare and has improved the quality of life of patients.

Various biopharmaceuticals used for treating such diseases are monoclonal antibodies, erythropoietin, growth hormones, recombinant proteins, recombinant human insulin, purified proteins, interferon, vaccines, and other biopharmaceuticals. Factors such as high costs of biopharmaceuticals, entry of lowcost biosimilars, and risk of side-effects posed by biopharmaceuticals act as major restraints for the biopharmaceuticals market. The global biopharmaceuticals market was valued at US$ 161,851.6 Mn in 2014 and is expected to expand at a CAGR of 9.4% to reach US$ 278,232.9 Mn by 2020.

North America is the largest market for the biopharmaceuticals. This is due to technological advancements in the region. In terms of types, monoclonal antibodies are the fastest growing segment. In terms of therapeutic application, oncology is the largest segment in the biopharmaceuticals market.

Biopharmaceuticals have wide applications in the pharmaceutical industry.

The North America biopharmaceuticals market was valued at US$ 64,681.3 Mn in 2014 and is expected to reach US$ 111,598.2 Mn by 2020 at a CAGR of 9.5% over the forecast period. One of the latest trends in the global biopharmaceuticals market is outsourcing, wherein biopharmaceutical companies enter into partnerships with contract manufacturing organizations (CMOs) to produce biopharmaceutical drug substances. This reduces the overall investment to launch a new product in the market and helps gain market access with ease.

Pfizer, Inc., F. Hoffmann-La Roche AG, Johnson & Johnson Services, Inc., Sanofi, Amgen Inc., AbbVie Inc., Merck & Co., Inc., Biogen Idec, Bayer AG, Eli Lilly and Company, and Novartis AG are some of the leading players in the global market for biopharmaceuticals. Some of the other players in the biopharmaceuticals market are GlaxoSmithKline Plc, Bristol-Myers Squibb Company, AstraZeneca PLC, and Abbott Laboratories.

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020

Table of Content Chapter 1 Preface 14 1.1 Report Description 14 1.2 Research Methodology 15 1.3 Assumptions 15 Chapter 2 Market Synopsis 17 Chapter 3 Porter’s Five Forces Analysis 19 3.1 Bargaining Power of Suppliers 19 3.2 Bargaining Power of Buyers 20 3.3 Threat of New Entrants 20 3.4 Threat of Substitutes 21 3.5 Intensity of Rivalry 21 Chapter 4 Market Overview 22 4.1 Market Definition 22 4.2 Market Drivers 26

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 4.2.1 Increasing aging population 26 4.2.2 Rising cases of chronic diseases 27 4.2.3 Technological advancements 28 4.2.4 Increasing R&D investments 28 4.3 Impact Analysis of Market Drivers 30 4.4 Restraints 31 4.4.1 High costs of biopharmaceuticals 31 4.4.2 Entry of low-cost biosimilars 31 4.4.3 Risk of side effects posed by biopharmaceutical drugs 32 4.5 Impact Analysis of Market Restraints 33 4.6 Opportunities 34 4.6.1 Diseases with high unmet needs 34 4.6.2 Emerging markets 34 4.6.3 Increasing new pipeline products 35 4.7 Trends 36 4.7.1 Outsourcing trends 36 Chapter 5 Global Market Size and Forecast 37 Chapter 6 Market Size and Forecast by Type 43 6.1 Monoclonal Antibodies 43 6.2 Recombinant Proteins 45 6.3 Granulocyte-Colony Stimulating Factor (G-CSF) 47 6.4 Interferons 49 6.5 Recombinant Human Insulin 51 6.6 Erythropoietin 53 6.7 Vaccines 55 6.8 Growth Hormones 57 6.9 Purified Proteins 59 6.10 Others 61 Chapter 7 Market Size and Forecast by Therapeutic Application 64 7.1 Metabolic Disorders 64 7.2 Oncology 66 7.3 Neurological Disorders 68

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 7.4 Cardiovascular Diseases 70 7.5 Inflammatory and Infectious Diseases 72 7.6 Others 74 Chapter 8 Market Size and Forecast by Geography 77 8.1 North America 77 8.1.1 Scenario in the U.S. 79 8.1.2 Scenario in Canada 84 8.2 Europe 90 8.2.1 Scenario in the U.K. 93 8.2.2 Scenario in Germany 98 8.2.3 Scenario in France 103 8.2.4 Scenario in Russia 108 8.2.5 Scenario in Italy 114 8.2.6 Scenario in Spain 118 8.3 Asia 123 8.3.1 Scenario in Japan 126 8.3.2 Scenario in China 130 8.3.3 Scenario in India 135 8.4 Rest of the World 140 8.4.1 Scenario in Brazil 142 8.4.2 Scenario in Australia 147 Chapter 9 Competitive Scenario 153 9.1 Competitive Benchmarking 153 9.2 Company Share Analysis 155 Chapter 10 Company Profiles 157 10.1 Abbott Laboratories 157 10.1.1 Company overview 157 10.1.2 Products and services 158 10.1.3 Financial performance 158 10.1.4 Key developments 159 10.2 Pfizer, Inc. 160 10.2.1 Company overview 160

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 10.2.2 Products and services 160 10.2.3 Financial performance 161 10.2.4 Key developments 161 10.3 Eli Lilly and Company 162 10.3.1 Company overview 162 10.3.2 Products and services 162 10.3.3 Financial performance 163 10.3.4 Key developments 163 10.4 Sanofi 164 10.4.1 Company overview 164 10.4.2 Products and services 164 10.4.3 Financial performance 165 10.4.4 Key developments 166 10.5 AbbVie Inc. 167 10.5.1 Company overview 167 10.5.2 Products and segments 167 10.5.3 Financial performance 168 10.5.4 Key developments 168 10.6 Novartis AG 169 10.6.1 Company overview 169 10.6.2 Products and services 170 10.6.3 Financial performance 170 10.6.4 Key developments 171 10.7 AstraZeneca plc 172 10.7.1 Company overview 172 10.7.2 Products and services 172 10.7.3 Financial performance 173 10.7.4 Key developments 173 10.8 Amgen, Inc. 175 10.8.1 Company Overview 175 10.8.2 Product and Services 175 10.8.3 Financial Performance 176 10.8.4 Recent Developments 176 10.9 Biogen Idec 178 10.9.1 Company Overview 178

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 10.9.2 Product and Services 178 10.9.3 Financial Performance 179 10.9.4 Recent Developments 179 10.10 GlaxoSmithKline Plc 182 10.10.1 Company overview 182 10.10.2 Products and services 182 10.10.3 Financial performance 183 10.10.4 Key developments 183 10.11 Bristol-Myers Squibb Company 185 10.11.1 Company overview 185 10.11.2 Products and services 185 10.11.3 Financial performance 186 10.11.4 Key developments 186 10.12 Bayer AG 187 10.12.1 Company overview 187 10.12.2 Products and segments 187 10.12.3 Financial performance 188 10.12.4 Key developments 188 10.13 Merck & Co., Inc. 190 10.13.1 Company overview 190 10.13.2 Products and services 190 10.13.3 Financial performance 191 10.13.4 Key developments 191 10.14 F. Hoffmann-La Roche, Ltd. 192 10.14.1 Company overview 192 10.14.2 Products and services 192 10.14.3 Financial performance 193 10.14.4 Key developments 193 10.15 Johnson & Johnson Services, Inc. 195 10.15.1 Overview 195 10.15.2 Products and Segments 195 10.15.3 Financial Performance 196 10.15.4 Strategic Development 196 List of Table

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020

TABLE 1 Market snapshot: biopharmaceuticals market, 2014 and 2020 18 TABLE 2 Drivers for biopharmaceutical market: Impact analysis 30 TABLE 3 Restraints for biopharmaceutical market: Impact analysis 33 TABLE 4 Global biopharmaceuticals market size, by region, 2010 – 2013 (USD Mn) 37 TABLE 5 Global biopharmaceuticals market size, by region, 2014 – 2020 (USD Mn) 38 TABLE 6 Global biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 39 TABLE 7 Global biopharmaceuticals market size, by usage, 2014 – 2020 (USD Mn) 40 TABLE 8 Global biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 41 TABLE 9 Global biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 42 TABLE 10 Global monoclonal antibodies market size, by region, 2010 – 2013 (USD Mn) 44 TABLE 11 Global monoclonal antibody market size, by region, 2014 – 2020 (USD Mn) 45 TABLE 12 Global recombinant proteins market size, by region, 2010 – 2013 (USD Mn) 46 TABLE 13 Global recombinant proteins market size, by region, 2014 – 2020 (USD Mn) 47 TABLE 14 Global granulocyte-colony stimulating factor market size, by region, 2010 – 2013 (USD Mn) 48 TABLE 15 Global granulocyte-colony stimulating factor market size, by region, 2014 – 2020 (USD Mn) 49 TABLE 16 Global interferons market size, by region, 2010 – 2013 (USD Mn) 50 TABLE 17 Global interferons market size, by region, 2014 – 2020 (USD Mn) 51 TABLE 18 Global recombinant human insulin market size, by region, 2010 – 2013 (USD Mn) 52 TABLE 19 Global recombinant human insulin market size, by region, 2014 – 2020 (USD Mn) 53 TABLE 20 Global erythropoietin market size, by region, 2010 – 2013 (USD Mn) 54 TABLE 21 Global erythropoietin market size, by region, 2014 – 2020 (USD Mn) 55 TABLE 22 Global vaccines market size, by region, 2010 – 2013 (USD Mn) 56 TABLE 23 Global vaccines market size, by region, 2014 – 2020 (USD Mn) 57 TABLE 24 Global growth hormones market size, by region, 2010 – 2013 (USD Mn) 58 TABLE 25 Global growth hormones market size, by region, 2014 – 2020 (USD Mn) 59 TABLE 26 Global purified proteins market size, by region, 2010 – 2013 (USD Mn) 60 TABLE 27 Global purified proteins market size, by region, 2014 – 2020 (USD Mn) 61 TABLE 28 Global other market size, by region, 2010 – 2013 (USD Mn) 62

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 TABLE 29 Global other market size, by region, 2014 – 2020 (USD Mn) 63 TABLE 30 Global metabolic disorders market size, by region, 2010 – 2013 (USD Mn) 65 TABLE 31 Global metabolic disorders market size, by region, 2014 – 2020 (USD Mn) 66 TABLE 32 Global oncology market size, by region, 2010 – 2013 (USD Mn) 67 TABLE 33 Global oncology market size, by region, 2014 – 2020 (USD Mn) 68 TABLE 34 Global neurological disorders market size, by region, 2010 – 2013 (USD Mn) 69 TABLE 35 Global neurological disorders market size, by region, 2014 – 2020 (USD Mn) 70 TABLE 36 Global cardiovascular diseases market size, by region, 2010 – 2013 (USD Mn) 71 TABLE 37 Global cardiovascular diseases market size, by region, 2014 – 2020 (USD Mn) 72 TABLE 38 Global inflammatory and infectious diseases market size, by region, 2010 – 2013 (USD Mn) 73 TABLE 39 Global inflammatory and infectious diseases market size, by region, 2014 – 2020 (USD Mn) 74 TABLE 40 Global others market size, by region, 2010 – 2013 (USD Mn) 75 TABLE 41 Global others market size, by region, 2014 – 2020 (USD Mn) 76 TABLE 42 The North American biopharmaceuticals market size, by country, 2010 – 2013 (USD Mn) 78 TABLE 43 The North American biopharmaceuticals market size, by country, 2014 – 2020 (USD Mn) 79 TABLE 44 The U.S. biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 81 TABLE 45 The U.S. biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 82 TABLE 46 The U.S. biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 83 TABLE 47 The U.S. biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 84 TABLE 48 Canadian biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 86 TABLE 49 Canadian biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 87 TABLE 50 The Canadian biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 88 TABLE 51 Canadian biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 89 TABLE 52 The European biopharmaceuticals market size, by country, 2010 – 2013 (USD Mn) 92 TABLE 53 The European biopharmaceuticals market size, by country, 2014 – 2020 (USD Mn) 93

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 TABLE 54 The U.K. biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 95 TABLE 55 The U.K. biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 96 TABLE 56 The U.K. biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 97 TABLE 57 The U.K. biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 98 TABLE 58 German biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 100 TABLE 59 German biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 101 TABLE 60 German biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 102 TABLE 61 German biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 103 TABLE 62 French biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 105 TABLE 63 French biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 106 TABLE 64 French biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 107 TABLE 65 French biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 108 TABLE 66 Russian biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 110 TABLE 67 Russian biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 111 TABLE 68 Russian biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 112 TABLE 69 Russian biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 113 TABLE 70 Italian biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 115 TABLE 71 Italian biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 116 TABLE 72 Italian biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 117 TABLE 73 Italian biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 118 TABLE 74 Spanish biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 120 TABLE 75 Spanish biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 121 TABLE 76 Spain biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 122

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 TABLE 77 Spain biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 123 TABLE 78 The Asian biopharmaceuticals market size, by country, 2010 – 2013 (USD Mn) 125 TABLE 79 The Asian biopharmaceuticals market size, by region, 2014 – 2020 (USD Mn) 125 TABLE 80 Japanese biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 127 TABLE 81 Japanese biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 128 TABLE 82 Japanese biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 129 TABLE 83 Japanese biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 130 TABLE 84 Chinese biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 132 TABLE 85 Chinese biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 133 TABLE 86 Chinese biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 134 TABLE 87 Chinese biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 135 TABLE 88 Indian biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 137 TABLE 89 Indian biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 138 TABLE 90 Indian biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 139 TABLE 91 Indian biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 140 TABLE 92 The Rest of the World biopharmaceuticals market size, by country, 2010 – 2013 (USD Mn) 141 TABLE 93 Global biopharmaceuticals market size, by region, 2014 – 2020 (USD Mn) 142 TABLE 94 Brazilian biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 144 TABLE 95 Brazilian biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 145 TABLE 96 Brazilian biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 146 TABLE 97 Brazilian biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 147 TABLE 98 Australian biopharmaceuticals market size, by type, 2010 – 2013 (USD Mn) 149 TABLE 99 Australian biopharmaceuticals market size, by type, 2014 – 2020 (USD Mn) 150 TABLE 100 Australian biopharmaceuticals market size, by therapeutic application, 2010 – 2013 (USD Mn) 151

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 TABLE 101 Australian biopharmaceuticals market size, by therapeutic application, 2014 – 2020 (USD Mn) 152 TABLE 102 Product categories of Abbott Laboratories 158 TABLE 103 Product category of Pfizer, Inc. 160 TABLE 104 Product category of Eli Lilly and Company 162 TABLE 105 Product categories of Sanofi 164 TABLE 106 Product segment of AbbVie Inc. 167 TABLE 107 Novartis AG’s product categories 170 TABLE 108 AstraZeneca plc’s product categories 172 TABLE 109 Amgen, Inc. product category 175 TABLE 110 Biogen Idec major therapies and their uses 178 TABLE 111 Major product categories of GlaxoSmithKline Plc 182 TABLE 112 Major product categories of Bristol-Myers Squibb Company 185 TABLE 113 Product categories of Bayer AG 187 TABLE 114 Major product categories of Merck & Co., Inc. 190 TABLE 115 Major product categories of Roche 192 TABLE 116 Johnson & Johnson Services, Inc.’s Product Categories 195 List of Figures FIG. 1 Biopharmaceuticals market: Porter’s five forces analysis 19 FIG. 2 Categorization of Biopharmaceuticals by Type 24 FIG. 3 Categorization of Biopharmaceuticals by Therapeutic Application 25 FIG. 4 Population aged 60 years and above in major countries, 2000 – 2050 26 FIG. 5 Comparison of percentage of Total biopharmaceutical revenues generation by major pharmaceutical companies, 2000 and 2012 29 FIG. 6 Global biopharmaceuticals market share, by region, by value, 2013 37 FIG. 7 Global biopharmaceuticals market share, by type, by value, 2013 39 FIG. 8 Global biopharmaceuticals market share, by therapeutic application, 2013 41 FIG. 9 Global monoclonal antibodies market share, by region, by value, 2013 44 FIG. 10 Global recombinant proteins market share, by region, by value, 2013 46 FIG. 11 Global granulocyte-colony stimulating factor market share, by region, by value, 2013 48 FIG. 12 Global interferons market share, by region, by value, 2013 50 FIG. 13 Global recombinant human insulin market share, by region, by value, 2013 52

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 FIG. 14 Global erythropoietin market share, by region, by value, 2013 54 FIG. 15 Global vaccines market share, by region, by value, 2013 56 FIG. 16 Global growth hormones market share, by region, by value, 2013 58 FIG. 17 Global purified proteins market share, by region, by value, 2013 60 FIG. 18 Global other market share, by region, by value, 2013 62 FIG. 19 Global metabolic disorders market share, by region, by value, 2013 65 FIG. 20 Global oncology market share, by region, by value, 2013 67 FIG. 21 Global neurological disorders market share, by region, by value, 2013 69 FIG. 22 Global cardiovascular diseases market share, by region, by value, 2013 71 FIG. 23 Global inflammatory and infectious diseases market share, by region, by value, 2013 73 FIG. 24 Global others market share, by region, by value, 2013 75 FIG. 25 North America biopharmaceuticals market share, by country, by value, 2013 78 FIG. 26 The U.S. biopharmaceuticals market share, by type, by value, 2013 80 FIG. 27 The U.S. biopharmaceuticals market share, by therapeutic application, by value, 2013 83 FIG. 28 Canadian biopharmaceuticals market share, by type, by value, 2013 85 FIG. 29 Canadian biopharmaceuticals market share, by therapeutic application, by value, 2013 88 FIG. 30 Europe biopharmaceuticals market share, by country, by value, 2013 91 FIG. 31 The U.K. biopharmaceuticals market share, by type, by value, 2013 94 FIG. 32 The U.K. biopharmaceuticals market share, by therapeutic application, by value, 2013 97 FIG. 33 German biopharmaceuticals market share, by type, by value, 2013 99 FIG. 34 German biopharmaceuticals market share, by therapeutic application, by value, 2013 102 FIG. 35 French biopharmaceuticals market share, by type, by value, 2013 104 FIG. 36 French biopharmaceuticals market share, by therapeutic application, by value, 2013 107 FIG. 37 Russian biopharmaceuticals market share, by type, by value, 2013 109 FIG. 38 Russian biopharmaceuticals market share, by therapeutic application, by value, 2013 112 FIG. 39 Italian biopharmaceuticals market share, by type, by value, 2013 114 FIG. 40 Italian biopharmaceuticals market share, by therapeutic application, by value, 2013 117

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 FIG. 41 Spanish biopharmaceuticals market share, by type, by value, 2013 119 FIG. 42 Spain biopharmaceuticals market share, by therapeutic application, by value, 2013 122 FIG. 43 Asian biopharmaceuticals market share, by country, by value, 2013 124 FIG. 44 Japanese biopharmaceuticals market share, by type, by value, 2013 126 FIG. 45 Japanese biopharmaceuticals market share, by therapeutic application, by value, 2013 129 FIG. 46 Chinese biopharmaceuticals market share, by type, by value, 2013 131 FIG. 47 Chinese biopharmaceuticals market share, by therapeutic application, by value, 2013 134 FIG. 48 Indian biopharmaceuticals market share, by type, by value, 2013 136 FIG. 49 Indian biopharmaceuticals market share, by therapeutic application, by value, 2013 139 FIG. 50 Rest of the World biopharmaceuticals market share, by country, by value, 2013 141 FIG. 51 Brazilian biopharmaceuticals market share, by type, by value, 2013 143 FIG. 52 Brazilian biopharmaceuticals market share, by therapeutic application, by value, 2013 146 FIG. 53 Australian biopharmaceuticals market share, by type, by value, 2013 148 FIG. 54 Australian biopharmaceuticals market share, by therapeutic application, by value, 2013 151 FIG. 55 Competitive landscape of biopharmaceuticals market, 2014 153 FIG. 56 Global Biopharmaceuticals market, by company 2014 (% share) 155 FIG. 57 Abbott Laboratories net sales and net earnings, 2012 – 2014 (USD Mn) 158 FIG. 58 Pfizer, Inc.’s Total revenue and net income, 2012 – 2014 (USD Mn) 161 FIG. 59 Eli Lilly and Company’s revenue and net income, 2012 – 2014 (USD Mn) 163 FIG. 60 Sanofi’s net sales and net income, 2012 – 2014 (USD Mn) 165 FIG. 61 AbbVie, Inc.’s net sales and net earnings, 2012 – 2014 (USD Mn) 168 FIG. 62 Novartis AG’s net sales and net income, 2012 – 2014 (USD Mn) 170 FIG. 63 AstraZeneca plc revenue and profit, 2012 – 2014 (USD Mn) 173 FIG. 64 Amgen, Inc. revenue and net income 2012 – 2014 (USD Mn) 176 FIG. 65 Biogen Idec revenue and net income 2012 – 2014 (USD Mn) 179 FIG. 66 GlaxoSmithKline plc’s turnover and profit, 2012 – 2014 (USD Mn) 183 FIG. 67 Bristol-Myers Squibb Company’s total revenue and net earnings, 2012 – 2014 (USD Mn) 186 FIG. 68 Bayer AG’s net sales and net income, 2011 – 2013 (USD Mn) 188

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Biopharmaceuticals Market - Global Market Study on Biopharmaceuticals Asia to Witness Highest Growth by 2020 FIG. 69 Merck & Co., Inc.’s sales and net income, 2012 – 2014 (USD Mn) 191 FIG. 70 Roche’s sales and net income, 2012 – 2014 (USD Mn) 193 FIG. 71 Johnson & Johnson Services, Inc., net sales and net earnings, 2012 – 2014 (USD Mn) 196 About Us: Persistence Market Research is a global market research firm specializing- syndicated research, custom research, and consulting services

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