Registration Brochure
June 15-17, 2017
St. Louis Union Station St. Louis, MO
AGT 42nd Annual Meeting
Dear Prospective AGT Annual Meeting Attendee: As the Annual Meeting Directors, it is our honor and privilege to invite you to historic St. Louis, Missouri for the 42nd Annual Meeting of the Association of Genetic Technologists. Much like St. Louis served as “The Gateway to the West” for those heading off to explore and chart the new frontier, we hope that this meeting will serve as a gateway of knowledge for attendees with expertise in cytogenetics, molecular genetics and biochemical genetics. Over the past year, we have worked diligently to develop this meeting, maintaining those areas of AGT excellence that you have come to expect, as well as enhancing those traditional offerings with fresh content and formats. We are honored to have Dr. Joshua Schiffman, pediatric hematologist-oncologist and world-renowned researcher, present the Keynote Address, which will undoubtedly inspire attendees on both the scientific and the human levels. We will continue the tradition of hosting a pre-conference day of interactive workshops followed by two days of scientific sessions, round-table discussions and platform presentations. We look forward to increased attendee participation as we share knowledge in these formal venues and as we exchange ideas informally during the social events and poster sessions. Our Annual Meeting could not be successful without the continued support of our corporate partners. We have numerous opportunities for attendees to engage with these partners, including a preconference Trivia Night, Welcome Reception, interactive workshops and designated exhibit hall hours throughout the meeting. We hope that you will use these opportunities to learn about new products and ways to enhance your laboratory protocols and to build professional, mutually-beneficial relationships. While we have a lot of learning to do while in St. Louis, the city’s history and culture also offer exciting opportunities to explore with colleagues or family. Enjoy the ambiance of St. Louis Union Station, a National Historic Landmark and site of the 2017 Annual Meeting, and dine at nearby restaurants. Consider a tour of the Anheuser-Busch Brewery, visit City Museum or take a ride up the Gateway Arch at Jefferson National Expansion Memorial. If you are passionate about the arts, Peabody Opera House might be the perfect night out for you. If you prefer sports, the St. Louis Cardinals offer exciting professional baseball for the fans in attendance. Whether you bring your family or make a friend at the meeting, St. Louis is sure to deliver a great summertime experience for all!
June 15-17, 2017
From our “behind the scenes” perspective, this meeting has us extremely energized and anxious for June! Our scientific session speakers are top-notch and bring a variety of expertise from across the country. You will earn the continuing education units (CEUs) necessary for your professional development and maintenance of certification. You will make professional connections that will extend well beyond the meeting hall. And, based on previous experience, you will do all of this while having a tremendous amount of fun!
St. Louis Union Station Hotel St. Louis, MO We hope you can all come along and “meet me in St. Louis, Louis”! 42nd Annual Meeting Program Directors Jennifer N. Sanmann, PhD, FACMG, Annual Meeting Director Christina Mendiola, CG(ASCP)CM, Annual Meeting Co-Director
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Registration Brochure
www.AGT-info.org
Quotes
from attendees of AGT’s 41st Annual Meeting: "The AGT meetings are always great – a good opportunity to connect to others in the field and a varied selection of speakers and topics." "A serious meeting to attend for those who take the profession seriously." "Energizing and inspiring!" "The AGT meeting is a wonderful opportunity to meet others, colleagues and vendors, who share the same passion for patient care and cytogenetic and molecular testing!" "Informative and forward thinking."
The 42nd Annual Meeting provides opportunities to earn continuing education credits and to develop professional contacts in the ever-expanding areas of clinical and research genetics. Scientific general sessions and pre-conference workshops offer participants the opportunity to learn about current and up-and-coming topics of interest in genetics. Expanded tracks for cytogenetic and molecular technologists allow attendees to focus their education. Additional time dedicated to platform presentations allow attendees to hear best practices and new research from their peers. Roundtable discussions and other networking opportunities allow attendees to share ideas and best practices with each other. The exhibit hall features vendors displaying the latest laboratory equipment, supplies and methodologies.
Continuing Education: 16.0 contact hours for scientific sessions Up to 8.0 contact hours for pre-conference workshops Up to 2.0 contact hours for poster viewing (1.0 contact hour per five posters viewed).
Authors/Presenters: 10.0 contact hours for first authors on abstracts 5.0 contact hours for additional authors
Join AGT Now! Take advantage of a special membership offer from AGT! Join AGT, pay the member registration fee and get member benefits starting July 1 through Dec. 31, 2018! You receive an additional six months of membership FREE and take advantage of the member registration fee – a $110 value!
10.0 contact hours for platform presentations Any changes will be noted in the Final Program. A continuing education certificate will be provided to you after the meeting based on the sessions you evaluate in the online evaluation. Please note that you must attend the entire meeting, and complete the online evaluation, in order to receive all available contact hours and your certificate of attendance.
42nd Annual Meeting Program Directors Jennifer N. Sanmann, PhD, FACMG, Annual Meeting Director Christina Mendiola, BS, CG(ASCP)CM, Annual Meeting Co-Director
Hotel & Travel Information page 9
Registration Form page 10
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Registration Brochure 3
June 15-17, 2017
AGT 42nd Annual Meeting
St. Louis Union Station St. Louis, MO
Meeting Schedule Thursday, June 15, 2017
how each of the six competency procedures can be achieved and documented in the laboratory setting.
Pre-Conference Workshops
8:00 a.m. – 9:50 a.m. Workshop 2: FISH Process Validation
8:00 a.m. – 11:50 a.m. Workshop 1: Management Series Includes the following four presentations
Norwood “Gene” Tosatto, CG(ASCP)CM, Senior Technologist, The Children’s Mercy Hospital
Maximizing Productivity & Employee Satisfaction in the Genetics Laboratory
Michelle Hess, MS, CG(ASCP)CM, Laboratory Manager, Human Genetics Laboratory, Munroe-Meyer Institute, University of Nebraska Medical Center
In today’s ever-changing healthcare environment it is important to make the best use of one's resources. The presenter will discuss her laboratory’s recent trek in evaluating resources to maximize productivity and identify areas for improvement. This process has involved evaluating benchmarks, work flow, role clarity and working with the HR department on detailed personal thinking preferences and their effect on teamwork and communication.
The presenter will describe the impact that ASR Regulation had and is still having in the FISH lab. He will discuss how to deal with these changes in the laboratory when it comes to development of new FISH tests on an individual laboratory basis.
10:00 a.m. - 11:50 a.m. Workshop 3: ISCN Workshop This workshop will include ISCN for G-banded chromosomes, FISH and array with an emphasis on oncology.
10:00 a.m. – 11:50 a.m. Workshop 4: PCR & Sequencing for the Cytogenetic Technologist Amy R. Groszbach, MEd, BS, MB(ASCP), MLT(ASCP), Education Coordinator, Mayo Clinic; Loren Simpson, BA, BS, Education Specialist II, Mayo Clinic
Preparing for CAP
Colleen Schloemann, CLSp(CG), Laboratory Quality Coordinator, SSM Health Cardinal Glennon Molecular Cytogenetics Laboratory The presenter will provide an overview on how to prepare for the CAP inspection. Audience participation is encouraged to share past CAP experiences. Change Is Easy, So Long as Someone Else Does the Changing
Thomas J. Gilfillan, MBA, CG(ASCP)CM, Operations Analyst/ Decision Support, The Colorado Genetics Laboratory
The presenters will review the concepts of PCR, the purpose of the PCR reagents, how to design primers, how to design PCR reactions, the concepts of sequencing, the purpose of the sequencing reagents and how to interpret and score sequencing electropherograms. There will also be hands-on activities involving primer design and the interpretation of sequencing results.
12:00 p.m. - 1:50 p.m.
Workshop 5: FISHing with the Real-Life Laboratory Experts An interactive workshop, run by FISH users for FISH users, providing an opportunity to share knowledge and experience. Lunch provided to the first 25 attendees. Sponsored by OGT
June 15-17, 2017
The presenter will focus on one laboratory’s investment in and insights gained from a two-year partnership with an accredited healthcare change program – the Institute for Healthcare Quality, Safety and Efficiency (IHQSE).
1:30 p.m. – 4:20 p.m.
Workshop Union 6: Proven Value in the Outcome-Based St. Louis Station Hotel Creating & Implementing a Competency Assessment Education of Fellows, Residents & Allied Health Staff at the Program Mayo Clinic Cytogenetic & Molecular Genetic Laboratories Andrea Fuentes, CG(ASCP), Medical Laboratory Scientist, St. Louis, MO – A Panel Discussion Specialist, Duke University Health Systems
The Clinical Laboratory Improvement Amendments (CLIA) mandates evaluating the competency of all testing personnel and assuring that the staff maintain their competency to perform test procedures and report test results promptly, accurately and proficiently through six competency procedures. This presentation will focus on the when, why, who, and how’s of creating and implementing a compliant competency assessment program, as well as
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Registration Brochure
Jason A. Yuhas, BS, CG(ASCP)CM; Amy Groszbach, MEd, BS, MB(ASCP), MLT(ASCP); Mark Junge, CG(ASCP)CM; Daniel Kuffel, CG(ASCP)CM; Nicole A. Lockwood, MBA; Loren Simpson, BA, BS; Kristin Stenzel, BS, CG(ASCP); Frank Suera, CG(ASCP)CM; Tammy Torgerson, CG(ASCP)CM, Genomic Lab Education Specialists, Mayo Clinic
www.AGT-info.org
One of the greatest challenges to high-complexity testing laboratories is establishing and maintaining superior quality, outcome-based education and on-the-job training programs. With well over 50 years of combined education experience, Mayo’s Lab Genomics Education Specialists (ES) have defined successful training protocols with focus on the education of all aspects of the genetic testing process. Each ES will highlight their specific role(s) in the education process and how their training is maximized within a large laboratory setting. Panel discussion, with question and answer sessions, will follow every presented portion of the workshop. Bring your questions and training scenarios, and Mayo’s ESes will do their best to help you find a novel way to address your training concerns. 1:30 p.m. – 2:50 p.m. Workshop 7: SNP 101 – High Resolution Microarray Testing in Clinical Practice Veronica Ortega, BA, CG(ASCP)CM, Laboratory Manager, University of Texas Health Science Center-San Antonio; Mark A. Rolla, BS, CG(ASCP)CM, Cytogenetic Supervisor, ACL Laboratories Single nucleotide polymorphism (SNP) based microarray testing is proven to be powerful genomic technology for diagnosis of many genetic disorders, especially in children with developmental delay, multiple congenital anomalies and neuropsychiatric disorders. This presentation will focus on the efficacy of SNP microarray testing as evidenced with case examples in the clinical setting.
2:30 p.m. – 4:20 p.m. Workshop 8: Uncovering the Technology, Opportunities & Economic Impact of the New Cytogenetics Workflow John McCloskey, Director of Sales, North America, ADS Biotec, Inc.; Brian Kirk, General Manager, Molecular Diagnostics, BioDot, Inc.; Hilary Frayer, Central Regional Sales Manager, Applied Spectral Imaging Over the past few years, ADS, BioDot, and ASI, leaders in cytogenetics automation, have worked together to develop an integrated workflow for FISH and cytogenetics that now challenges traditional paradigms with respect to cost, turn-around-time, quality and consistency. As this workflow continues to establish itself in the industry, new opportunities are emerging for those who understand its positive impact and are able to help implement it in their current environment. The presenters will explain how automation, software and multiplexing are becoming powerful tools as labs push back against reduced reimbursement and growing test volume. Come learn from developers of the technology and current users as they help walk everyone through the process from beginning to end.
of multiplexing and miniaturization to where it is needed most — analysis. • GenASIs SpotScan Automated Scanning System is optimized to identify the FISHArray slide. Through its cell detection, segmentation and accurate classification based on cell signal pattern, it delivers results that have changed cytogenetics. Sponsored by BioDot, Applied Spectral Imaging and ADS Biotec
3:00 p.m. – 4:20 p.m. Workshop 9: Grab Your Seat & Don’t Get Left behind: Transitioning from Classical Cytogenetics to Molecular Genetics Marilu Nelson, MS, CG, MB(ASCP)CM, Laboratory Supervisor, Human Genetics Laboratory, Munroe-Meyer Institute, University of Nebraska Medical Center If you are one of the fortunate individuals who have enjoyed many years in the study of cytogenetics it may seem the field has been moving at warp speed, and the train has already left the station. Staying abreast of all the changes does require some effort, but it’s definitely a worthwhile investment. The presenter will discuss how to properly harness the vast knowledge you gained through doing things like cell culture, karyotyping and FISH and apply it to emerging technologies. We can look forward to some amazing developments in genetic sciences, and the good news is that there is a seat on the train for all of us.
4:30 p.m. – 6:00 p.m. TRIVIA NIGHT Please join AGT and Thermo Fisher Scientific for an evening of fun! This event will provide attendees with an opportunity to network and to show their genetics knowledge during a trivia session. Have a small team? Great! Flying solo? No problem! We will get you paired up with others when you arrive. This event will include drinks and light hors d'oeuvres, so come ready to eat, drink and think! Sponsored by Thermo Fisher Scientific
6:00 p.m. – 8:00 p.m. WELCOME RECEPTION IN EXHIBIT HALL/POSTER VIEWING/FGT SILENT AUCTION Don’t miss the opening of the AGT 42nd Annual Meeting with a Welcome Reception in the Exhibit Hall. The reception is an excellent opportunity to learn more about the latest services and products from our exhibitors. AGT will provide a variety of hors d’oeuvres and one drink ticket (beverages may be purchased after you have used your drink ticket). Attendance at the reception is included with your registration fee. If you would like a guest to attend the Welcome Reception, tickets can be purchased for $35.
The integrated solution: •
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The Hanabi Harvesting System establishes the foundation for a consistent and reliable process in any cell suspension cultures while meeting the throughput demands of small, mid-sized and high throughput environments. The CellWriter Workstation enables the FISHArray technology and manages the digital information that brings the benefits
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Registration Brochure 5
June 15-17, 2017
St. Louis Union Station St. Louis, MO
AGT 42nd Annual Meeting 11:25 a.m. – 12:15 p.m. Informing Clinical Interpretations of Structural Chromosome Rearrangements: Implementing Evolving Knowledge from Chromatin Structure
Friday, June 16, 2017 7:30 a.m. – 8:00 a.m. CONTINENTAL BREAKFAST IN THE EXHIBIT HALL
Cynthia Casson Morton, PhD, FFACMG, Director of Cytogenetics, William Lambert Richardson Professor of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women’s Hospital; Professor of Pathology, Harvard Medical School
7:00 a.m. - 4:00 p.m. EXHIBIT HALL OPEN
Scientific Sessions
Next-generation sequencing and knowledge of the 3D structure of the human genome are providing new insight into the diagnosis and clinical phenotypes of individuals with apparently balanced chromosome rearrangements. Dr. Morton will discuss her laboratory's research underway in the Developmental Genome Anatomy Project.
8:00 a.m. – 8:10 a.m. Welcome to the AGT 42nd Annual Meeting
12:15 p.m. – 1:45 p.m. LUNCH ON YOUR OWN
7:00 a.m. - 4:00 p.m. Agilent Microscope Demonstration
8:00 a.m. - 8:50 a.m. Opening Keynote Address Joshua D. Schiffman, MD, Associate Professor of Pediatrics, University of Utah; Adjunct Associate Professor, Department of Oncological Sciences, Division of Hematology/Oncology, Primary Children’s Medical Center; Medical Director, High Risk Pediatric Cancer Clinic, Huntsman Cancer Institute 9:00 a.m. – 9:50 a.m. Pharmacogenetics Victoria M. Pratt, PhD, FACMG, Director of Pharmacogenetics and Molecular Genetics Laboratories, Indiana University School of Medicine Pharmacogenetics is the study of how different groups of people respond to drugs, based on their genetic makeup. Dr. Pratt will explore some common drugs and the genes involved in their metabolism. She will also provide an overview of pharmacogenetic nomenclature and review guidelines that support pharmacogenetic testing.
Oncology Sessions 1:45 p.m. – 2:25 p.m. Laboratory Testing for Plasma Cell Neoplasia Denise I. Quigley, PhD, FACMGG, Medical Director, Cytogenetics, ARUP Laboratories Plasma cell neoplasms (PCNs) are a diverse group of disorders with varied clinical presentation and prognosis. There is little consensus regarding the approach to laboratory testing for PCNs, particularly molecular cytogenetic FISH panels. Approach to diagnostic and prognostic laboratory testing, including potential new molecular strategies will be discussed.
2:25 p.m. - 3:05 p.m. Neoplastic vs. Constitutional Copy Number Variants Identified by Chromosome Microarray Analysis in Cancer Specimens Jacqueline R. Batanian, PhD, ACMG C, Professor, Director of Molecular Cytogenetics Laboratory, Saint Louis University Unique chromosome rearrangements found in every cell of a neoplastic specimen need to be ruled out constitutionally. However, the identification of disruptive genes in the form of copy number variants within such balanced rearrangements raise another level of interpretation. Cytogenomic analysis was performed on patient bone marrows to rule out hematological disorders. Following conventional cytogenetic (CCA) and fluorescence-in situ hybridization (FISH) analyses, chromosome microarray analysis (CMA), patient bone marrows were found to carry copy number variants disrupting novel constitutional aberrations that may explain their excessive clinical feature.
June 15-17, 2017
9:50 a.m. – 10:35 a.m. BREAK IN EXHIBIT HALL/POSTER VIEWING/FGT SILENT AUCTION
Technical Sessions 10:35 a.m. – 11:25 a.m. NIPS/T: (Mis)Adventures in Confirmatory Testing
St. Louis Union Station Hotel St. Louis, MO
Stephen Moore, MBA, PhD, FACMG, Director, Cytogenetics and Molecular, Knight Diagnostic Laboratories; Assistant Professor, Oregon Health and Science University Dr. Moore will discuss approaches for confirming non-invasive prenatal testing and testing results in an academic clinical laboratory and what his lab has learned about positive and false positive test results.
3:05 p.m. - 3:45 p.m. Molecular & Cytogenetic Tools in the Characterization of Aggressive B-cell Lymphomas Nathan D. Montgomery, MD, PhD, Molecular Genetic Pathology Fellow, The University of North Carolina School of Medicine Cytogenetic and molecular tools are increasingly fundamental in the diagnosis, classification and treatment of hematolymphoid
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Registration Brochure
www.AGT-info.org
neoplasms. In the 2016 revision of the World Health Organization classification, many lymphomas are now defined by their cytogenetic characteristics, much as occurred with myeloid lesions in earlier versions of the classification. In this session, key cytogenetic findings in the classification of high grade B-cell lymphomas will be reviewed, with an emphasis on the important role of fluorescence in situ hybridization, chromosomal microarrays and even conventional karyotype. Areas of special attention will include newly recognized entities such as “High grade B-cell lymphoma with abnormalities of MYC and BCL2 and/or BCL6” and “Burkitt-Like lymphoma with 11q abnormalities.” In addition, the emerging role of next generation sequencing assays as diagnostic and prognostic tools in lymphoid neoplasia will be considered.
3:45 p.m. – 4:20 p.m. BREAK IN EXHIBIT HALL/POSTER VIEWING/FGT SILENT AUCTION
Constitutional Sessions 4:20 p.m. – 5:10 p.m. Applications of Genomics in Pediatrics Emily G. Farrow, PhD, CGC, Director of Laboratory Operations, Center for Pediatric Genomic Medicine; Assistant Professor, Children’s Mercy Hospitals and Clinics Next generation sequencing has rapidly changed the landscape of genomic testing. Dr. Farrow will discuss current ways that genomics is being implemented in a pediatric hospital.
5:10 p.m. – 6:00 p.m. Genetics & Genomics of Fanconi Anemia Lisa Dyer, PhD, Co-Director of Cytogenetics, Cincinnati Children’s Hospital Medical Center Fanconi Anemia is a rare, inherited bone marrow failure syndrome that, over time, can lead to aplastic anemia and cancer. Cincinnati Children’s Hospital Medical Center has been performing Fanconi Anemia chromosomal breakage analysis and complementary next-generation sequencing diagnostic testing for several years. Dr. Dyer will describe the clinical phenotype of Fanconi Anemia, the appropriate diagnostic testing algorithm and provide some casebased lessons learned about this rare disorder.
6:00 p.m. – 7:00 p.m. AGT JOB FAIR AGT has invited laboratories and other organizations with employment opportunities for technologists to participate at its annual Job Fair. You may find the job that you have been looking for or just satisfy your curiosity by discovering the other employment opportunities available. The Job Fair will allow you to network in a casual atmosphere with potential employers and fellow professionals one-on-one. Attendance at the Job Fair is complimentary and open to the public.
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Saturday, June 17, 2017 7:00 a.m. – 7:45 a.m. BUSINESS MEETING BREAKFAST This complimentary breakfast provides the opportunity for both members and non-members to learn more about the Association, meet the incoming Board of Directors, get the latest updates on AGT activities and hear updates from other organizations.
7:00 a.m. - 2:00 p.m. EXHIBIT HALL OPEN 7:00 a.m. - 2:00 p.m. Agilent Microscope Demonstration
Scientific Sessions 8:00 a.m. – 8:10 a.m. Opening Remarks & Announcements Patricia Dowling, PhD, FACMG, Director, Cytogenetics, HistoPathology Services, Pathline Labs; AGT President Jennifer N. Sanmann, PhD, FACMG, Interim Director and Assistant Professor, Human Genetics Laboratory at the MunroeMeyer Institute, University of Nebraska Medical Center; AGT Annual Meeting Director 8:10 a.m. – 9:00 a.m. Gordon W. Dewald Lecture: FISH - The Land of Opportunity in the World of Make Believe Rhett P. Ketterling, MD, Co-Director, Laboratory; Professor of Laboratory Medicine and Pathology, Mayo Clinic 9:00 a.m. – 9:50 a.m. I Just Want to Develop a Good Test! Navigating Guidelines & Validation Requirements Catherine Rehder, PhD, Assistant Professor/Director, Duke Cytogenetics Laboratory; Associate Director, Duke Molecular Diagnostics Laboratory Laboratories strive to deliver the highest quality analytical services to their patients and physician clients. Many groups, including CAP, ACMG, AMP, CLSI and the FDA, issue guidance documents to ensure that all laboratories provide the highest caliber testing. In this session, Dr. Rehder will discuss these various groups and their guidelines, highlighting test validation procedures.
9:50 a.m. – 10:30 a.m. BREAK IN EXHIBIT HALL/POSTER VIEWING/FGT SILENT AUCTION
Registration Brochure 7
June 15-17, 2017
AGT 42nd Annual Meeting
St. Louis Union Station St. Louis, MO Treatment Sessions
area. Of note is the critical role of cytogenetics in the diagnosis of myeloid neoplasms, as highlighted by the inclusion of recurrent cytogenetic abnormalities in the World Health Organization classification of these diseases. Dr. Williams will focus on the effective implementation of NGS into the genetic workup of myeloid neoplasms, including challenges and opportunities of NGS-based testing, as well as a comparison and correlation of NGS results with cytogenetic results.
10:30 a.m. – 11:20 a.m. The Pathway to FDA Approval for NGS Companion Diagnostics Philip D. Cotter, PhD, FACMGG, FFSc(RCPA), Laboratory Director, ResearchDx, Inc. The FDA has prescribed a pathway for the co-approval of therapeutics and companion diagnostics. In recent years, a number of molecular companion diagnostics have been FDA approved. Dr. Cotter will provide an overview of, and discusses the pathway to, FDA approval using an NGS-based companion diagnostic in oncology as an example.
11:20 a.m. – 12:10 p.m. Cytogenetic Studies Supporting the Development of New Immunotherapy for B-cell Acute Lymphoblastic Leukemia Vania Aikawa, MD, Laboratory Supervisor, University of Pennsylvania Immune-based therapies represent an effective treatment modality for hematologic malignancies. Conventional cytogenetics and fluorescence in situ hybridization (FISH) may be utilized to support the development of new immunotherapies, such as chimeric antigen receptors (CARs), which have shown impressive results in B-cell acute lymphoblastic leukemia.
2:30 p.m. – 3:45 p.m. Roundtable Discussions: Expanding Knowledge through Dialogue Join in a lively discussion on topics of interest to you! Participants will have a choice of molecular, cytogenetics, education and compliance topics, and discussion leaders will guide the conversation regarding the issues relevant to genetic technologists. A great networking and information gathering opportunity!
2:30 p.m. – 3:10 p.m. 2A. Molecular Roundtable Discussions • • • • • •
Sequencing – Constitutional Sequencing – Somatic Variant Analysis MLPA & Other Molecular Techniques Sequencing Nomenclature Expansion Repeat Analysis
2B. Cytogenetics Roundtable Discussions
12:10 p.m. – 1:45 p.m. LUNCH ON YOUR OWN
Concurrent Tracks 1:45 p.m. – 2:30 p.m. 1A. Strategic Genetic Testing Algorithms for Diagnosis Yoshiko Mito, PhD, FACMG, Associate Director of Cytogenetics and Molecular Pathology; Assistant Professor of Pathology and Immunology, Washington University School of Medicine With an ever-growing number and variety of genetic diagnostic tests, it is critical to understand the benefits and limitations of each testing method and determine testing algorithms strategically. In this session, Dr. Mito will discuss clinical cases in which the initial genetic testing revealed unexpected results and a strategically selected series of follow-up testings led to diagnosis.
• • • • • • • •
FISH – Technical FISH – Assessment COG Nomenclature – Oncological Nomenclature – Constitutional Array Tissue Culture – Long-Term Tissue Culture – Suspension
3:10 p.m. – 3:45 p.m. 3A. Education & Career Development Roundtable Discussions
June 15-17, 2017 • • • • •
Certification – Molecular Certification – Cytogenetics Management Professional Engagement Mentorship
St. Louis Union Station Hotel 1B. Incorporating NGS into the Genetic Work-up of St. Louis, MO Myeloid Neoplasms Eli Williams, PhD, FACMG, Director of Cytogenetics, Co-Scientific Director of Clinical Genomics, University of Virginia Next generation sequencing (NGS) based assays are being implemented in a variety of clinical settings. Whole genome sequencing and whole exome sequencing have been successful in identifying disease-causing genetic variants in a variety of constitutional disorders. However, the clinical utility of NGS in cancer applications is less clear, whereas cytogenetics has well-established utility in this
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Registration Brochure
3B. Compliance & Quality Roundtable Discussions • • • • • • •
CAP – Molecular CAP – Cytogenetics Proficiency Testing Automation Validation FISH Assay Validation Molecular Assay Validation Banding Quality
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3:45 p.m. – 4:00 p.m. BREAK
5:30 p.m. Closing Remarks
4:00 p.m. – 5:30 p.m. 4A. Molecular/Biochemical Platform Presentations
6:30 p.m. – 9:00 p.m. ANNUAL AWARDS BANQUET
Six abstracts in the areas of biochemical and molecular genetics will be selected for presentation.
Join us to celebrate the last evening of the meeting by honoring our award winners and thanking our sponsors for their support. AGT will provide dinner and one drink ticket (beverages can be purchased after you have used your drink ticket). This is a wonderful opportunity to network with your colleagues from across the country one last time! Prize drawings will also take place during this time. You must be present to win!
4B. Cytogenetics Platform Presentations Six abstracts in the area of cytogenetics will be selected for presentation.
Hotel & Travel Information St. Louis Union Station Hotel 1820 Market St. St Louis, MO, 63103 314-231-1234
Make hotel reservations at http://group.curiocollection.com/ assngenetictech17. For additional reservation help, please call 314-231-1234.
Hall Market for a morning Starbucks coffee and grab a local treat or souvenir. After a busy day in St. Louis, unwind with one of our many hotel amenities. Workout in the fitness center, swim some laps in the outdoor seasonal pool and revel in The Grand Hall Experience 3D Light Show. Hotel description from St. Louis Union Station Hotel’s website.
Ground Transportation in St. Louis
St. Louis Union Station is approximately 17 miles from Lambert-St. Louis International Airport. We suggest the following methods of transportation to and from the hotel:
Rate: $149; rate includes guestroom wireless Internet
GO Best Express Airport Shuttle – $16 per person one way. Reservations MUST be made in advance.
Reservation Deadline: May 22, 2017
Taxi – Rates may vary, estimated cost is $52 one way.
Within sweeping archways, fresco and gold leaf detailing, mosaics and glass windows, you’ll find the St. Louis Union Station Hotel, Curio Collection by Hilton. This AAA Four Diamond Hotel provides a truly elegant experience in the heart of a bustling metropolitan area. Transport yourself to a time when travel was an art and the fine details were important. Every guest room boasts timeless décor, a work area, a flat screen TV and spacious bathroom. Opt for a suite with a courtyard view, concierge lounge access and added amenities. Several suites offer exclusive access on the historical side of the building and are individually railroad themed. Dining is a unique experience at the Union Station hotel with offerings ranging from upscale American cuisine to a quick sandwich or pastry. Savor delicious breakfast, lunch and dinner at the Station Grille with lovely fountain views. Stop by the Grand
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For the convenience of the guests, St. Louis Union Station is pleased to offer valet parking for $35. Self-parking is available but is not in close proximity to the hotel entrance.
Weather
St. Louis’s average daytime temperature in June is in the mid80s, and the average nighttime temperature is in the mid-60s.
Attire
Attire for the meeting and all social functions is business casual. Meeting rooms are often chilly so bring a sweater or jacket for the sessions.
Registration Brochure 9
AGT 42nd Annual Meeting
REGISTRATION FORM
Register one person per form. Please use photocopies for additional registrants. To register online, please visit the AGT website at www.AGT-info.org.
STEP 1: Name Badge & Roster Information First Name
Last Name
Name Preferred on Name Badge Company/Institution Business Address City State/Province Business Phone
Zip/Postal Code Cell Phone (to be used in case of emergency)
Country Email
_______________________________________________________________________________________________________________________ Specific requests (subject to availability)
Vegetarian Vegan Gluten-Free
Other (describe allergies here)_____________________________________________________
I am a new AGT member since June 2016.
STEP 4: Pre-Conference Workshops – Thursday, June 15
This is the first AGT meeting that I have attended.
NEW THIS YEAR: Pay one fee and attend a full- or half-day of workshops! Mix and match workshops below. See pages 4-9 for full titles and descriptions.
I DO NOT consent to allow my photo to be taken during the meeting to be published on AGT social media sites, AGT website or in publications to promote AGT or the Annual Meeting.
Emergency Contact
Please ensure that the workshops you select do not overlap! Space is limited and will be assigned on a first-come, first-serve basis.
Emergency Contact Name/Relationship/Phone
Full-Day Fee: $125 (mix and match morning and afternoon workshops to create a full-day)
STEP 2: Join AGT! Join AGT now and register for the Annual Meeting at the member price below. Membership will run through December 31, 2018.
Morning Workshops:
Join AGT (membership benefits will begin in July) Full - $95 Emeritus - $40 Student - $35 Collaborative - $40
8:00 - 11:50 - Workshop 1 8:00 - 9:50 - Workshop 2
STEP 3: Full & Single-Day Registration Fees On or before April 22After May 19 April 21 May 19 - On-Site Member $350 $400 $425 Non-Member $460 $510 $535 Student $125 $150 $170 Single-Day Member $185 $210 $220 Single-Day Non-Member $245 $265 $285 Single-Day Student $65 $85 $95 Single-Day Registration Only: Please indicate day attending: Friday, June 16 Saturday, June 17
Fees:
Half-Day Fee: $75 (mix and match workshops from either the morning OR afternoon sessions to create a half-day)
10:00 - 11:50 - Workshop 3 10:00 - 11:50 - Workshop 4
June 15-17, 2017 Afternoon Workshops:
1:30 - 4:20 - Workshop 6
1:30 - 2:50 - Workshop 7 Station Hotel St. Louis Union 3:00 - 4:20 - Workshop 9 St. Louis, MO OR choose one of the following complimentary workshops. 12:00 - 1:50 - Workshop 5 (Lunch provided for the first 25 attendees. You will be notified if you are outside of this 25.)
2:30 - 4:20 - Workshop 8
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Registration Brochure
www.AGT-info.org
AGT 42nd Annual Meeting
REGISTRATION FORM CONTINUED
STEP 5: Guest Registration
STEP 8: Send Your Registration
Are you bringing a guest to the Annual Meeting? Consider purchasing special events tickets so that your guest can join you at the following functions.
To register, complete the registration form and return it, along with the appropriate payment, to:
Welcome Reception Guest
(___ persons x $35)
Awards Banquet Guest
(___ persons x $45)
Guest Name:__________________________________________ Please note: Each attendee will receive one ticket to each event at no additional cost as part of the registration fee.
STEP 6: Total Fees Total Membership Fee
$__________
Total Registration Fee
$__________
Total Workshop Fee(s)
$__________
Total Guest Registration Fee(s)
$__________
Total Payment Enclosed
$__________
Mail: AGT Executive Office
4400 College Blvd., Ste. 220 Overland Park, KS 66211
Fax: 913-222-8606
Registration forms and payment information can be faxed.
Online Registration:
Registrations can be completed and submitted online via the AGT website at www.AGT-info.org. A link to online registration is located on the Annual Meeting page.
STEP 7: Payment Information
Payment is due in full with your registration form. Fees are based upon the postmark date. Payment may be made by credit card or check in U.S. funds drawn on a U.S. bank.
If you register online, enter code RB1 to be entered into a prize drawing!
Please make checks payable to the Association of Genetic Technologists (AGT) – Federal Tax ID #94-2668057 Check enclosed Credit Card MasterCard VISA American Express Discover Credit Card No. Expiration Date Signature Name as it appears on the card (please print) Cardholder Phone Number
Cancellations All fees must be paid in U.S. dollars, with checks drawn in U.S. funds from U.S. banks. In the event of cancellation prior to or on May 19, registration fees will be returned, less a $50 processing fee. All refunds on cancellations will be issued after the meeting. Substitutions are allowed. There will be no refunds issued or substitutions allowed after May 19.
www.AGT-info.org
Registration Brochure 11
4400 College Blvd., Ste. 220 Overland Park, KS 66211