Column: Dr. Oz and Rozien

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FROM KING FEATURES SYNDICATE, 300 W 57th STREET, 41st FLOOR, NEW YORK, NY 10019 CUSTOMER SERVICE: (800) 708-7311 EXT. 236 DRS. OZ AND ROIZEN FOR RELEASE WEEK OF JULY 4, 2021 BY MICHAEL ROIZEN, M.D., AND MEHMET OZ, M.D. Reboot your aging body for a stronger, mentally sharper you We’re at the dawn of a new age for healthy human aging. Recently, scientists have made astounding insights into how to turn back the clock on declining health, sagging muscles and fading brain power. Some of the new knowledge builds on what we have known for a while — that what you eat, how you sleep, your level of physical activity and your lifestyle habits all have the power to make your body and brain old before its time or to make your biological age a lot younger than your chronological age. But the latest science delivers some booster shots (don’t worry, no needles involved) that can super-power your life-enhancing efforts. One area of research into the mechanisms of aging is called induced tissue regeneration, or ITR. What is ITR? It’s a process of using drugs to reset your cells back to their immature stem cell stage so they can become, for example, brown fat cells, increasing your metabolic rate and defeating obesity, or so they can help renew body tissue, brain cells and neurological functions. One of the newcomers to this field is Calico Labs, Google’s mostly under-theradar division that’s devoted to anti-aging research and development. They explore things like how cells (in yeast) age and have untangled what happens to muscle stem cells over time that causes a decline in lean muscle mass and loss of muscle cells’ regenerative powers. Recently, they developed an experimental drug — an integrated stress response inhibitor, or ISRIB — that dramatically reverses age-related decline in memory and mental flexibility in mice. The researchers say the drug’s extremely rapid effects show that a significant component of age-related cognitive losses may be caused by a kind of reversible “blockage,” not an irreversible erosion of ability. A couple more anti-aging breakthroughs from other researchers are worth noting too: — A study in Plos Biology reveals that the aging brain is being cheated out of sufficient oxygen as a protein that helps red blood cells deliver the needed fuel declines. In lab mice, boosting the protein improves cognition and memory. To us it sounds like a huge endorsement for getting a lot of blood-pumping exercise as you age: at least 300 minutes a week. — Researchers have sounded the alarm about “inflammaging” — a contraction of

“inflammation” and “aging” — especially in the pituitary gland. Located at the base of your brain, this gland tells other glands to release hormones and affects your brain, skin, energy, mood, reproductive organs, vision, growth and more. But inflammaging prevents the pituitary gland’s cells from regenerating. So, you guessed it, tamp down the inflammation, and you may unleash the gland to do its keeping-you-younger good works. An anti-inflammatory plant-based diet, plenty of exercise and anti-inflammatory drugs might slow down pituitary aging or rejuvenate the gland. There’s more: Dr. Michael West has investigated the latest research on aging. He says blueberries are a storehouse of brain-protecting nutrients, especially anthocyanins. This flavonoid helps protect you from cardiovascular disease and Type-2 diabetes, promotes weight maintenance and provides neuroprotection. Anthocyanins are also found in other foods that are red, blue, purple or black. Coffee extract made from the whole coffee fruit also boosts mental performance — and Dr. Mike is a big fan of coffee’s many other benefits to your heart and head. Another brain-loving chemical is acetylcholine, the messenger that helps brain cells communicate and retrieve memories. It needs to be actively replenished as you get older, and you can help increase production by eating foods such as poultry, fish, cruciferous vegetables, beans, nuts, seeds and whole grains. All this fascinating info and more on how to beat unnecessary aging using the latest scientific insights will be in Dr. Mike’s upcoming book titled “The Great Age Reboot: Cracking the Longevity Code to Live Younger for Longer.” It’s about how to have a body that’s 20, 30 and 40 even when you’re 70. We hope this inspires you to pursue your younger self. *** Mehmet Oz, M.D. is host of “The Dr. Oz Show,” and Mike Roizen, M.D. is Chief Wellness Officer and Chair of Wellness Institute at Cleveland Clinic. To live your healthiest, tune into “The Dr. Oz Show” or visit www.sharecare.com. ©2021 Michael Roizen, M.D. and Mehmet Oz, M.D. Distributed by King Features Syndicate, Inc.


FROM KING FEATURES SYNDICATE, 300 W 57th STREET, 41st FLOOR, NEW YORK, NY 10019 CUSTOMER SERVICE: (800) 708-7311 EXT. 236 DRS. OZ AND ROIZEN FOR RELEASE WEEK OF JULY 4, 2021 BY MICHAEL ROIZEN, M.D., AND MEHMET OZ, M.D. Help! My partner is sleep talking; should I switch statins? Q: My partner has started talking in his sleep — a lot. Is it a sign of anxiety or something physically wrong? It’s ruining my sleep, and it can’t be good for his. How can I help him stop? — Jessica S., San Francisco A: Sleep talking is both common and almost always harmless — to the person doing the talking. It may be expressed in incoherent mumbles or be clear as a bell. It can be related to dreams or simply come from thoughts floating through a sleeping brain. The talkers usually have no idea it’s going on, and their sleep is not disturbed by it. It’s estimated that around 66% of folks have experienced sleep talking — but it isn’t something that is frequent or persistent. Sleep talking is not considered a health risk, but there are sleep disturbances that are linked to long-term health problems, such as mood disorders, cognition problems, heart disease, diabetes and even colorectal cancer. Sleep talking is also distinct from other conditions that trigger vocalization during sleep, such as catathrenia, a breathing disorder that causes audible groaning, and REM sleep behavior disorder, in which a person physically acts out a dream. Those conditions should be treated by a sleep specialist. Your best bet to tame the talk is to help your partner address stress and anxiety issues and adopt healthy sleep habits. That includes avoiding digital devices for 30 minutes before bedtime, meditating for 10 to 15 minutes before sleep, going to bed at a consistent time, reducing or eliminating alcohol consumption, and getting outside for 30 to 60 minutes of physical activity a day. And if your partner also sleepwalks or has nightmares, you should make an appointment with a sleep specialist to get an accurate diagnosis and treatment. In the meantime, earplugs might help you get a good night’s rest. *** Q: I’m 75 and a bit forgetful. My LDL cholesterol is pretty high, and my doctor wants me to take a statin, but I just read that it could increase my risk of dementia. Is there an alternative that might work as well for me? — Gregory T., Austin, Texas A: For a while now, there’s been conflicting info about statins’ effect on cognition.

While some studies have found that they decrease your risk for dementia, others have found that they may not help or even increase the risk. A recent study presented at the annual meeting of The Society of Nuclear Medicine and Molecular Imaging, that is intended to help clarify the impact of different types of statins, may be what you read about. While all statins are designed to lower bad LDL cholesterol and reduce the risk of heart attack and stroke, they don’t all work in the same way. Some, called hydrophilic statins, work in the liver to control the production of cholesterol; others, called lipophilic statins, are distributed to tissues throughout the body. Lipophilic statins were identified in that study as a risk to cognition — but only for certain people. The researchers found that study participants with low or moderate cholesterol levels and no or early mild cognitive impairment who took lipophilic statins (atorvastatin, simvastatin, lovastatin, etc.) doubled their risk of developing fullblown dementia. However, no such clinical or metabolic decline was found in users of other types of statins or for statin users having higher baseline serum cholesterol levels. So what’s your next step? We know that reducing lousy cholesterol levels and protecting your cardiovascular system is a powerful way to avoid some forms of dementia. We also know that the first — and safest — way to do that is to eliminate all red meats and dairy and shift to a plant-based diet. You can get great guidance on making this shift in Dr. Mike’s “What to Eat When Cookbook.” Your next step is to ask your doctor if it seems necessary to shift to another type of statin. That is a decision you must make together. *** Mehmet Oz, M.D. is host of “The Dr. Oz Show,” and Mike Roizen, M.D. is Chief Wellness Officer Emeritus at Cleveland Clinic. Email your health and wellness questions to Dr. Oz and Dr. Roizen at youdocsdaily(at sign)sharecare.com. ©2021 Michael Roizen, M.D. and Mehmet Oz, M.D. Distributed by King Features Syndicate, Inc.


FROM KING FEATURES SYNDICATE, 300 W 57th STREET, 41st FLOOR, NEW YORK, NY 10019 CUSTOMER SERVICE: (800) 708-7311 EXT. 236 DRS. OZ AND ROIZEN FOR RELEASE WEEK OF JULY 4, 2021 WEEKLY TIP PACKAGE BY MICHAEL ROIZEN, M.D., AND MEHMET OZ, M.D. Individual vitamin supplements — do’s and don’ts

When it comes to combining vitamins, it pays to know which may block each other from doing their good work and which may amplify their effects. Fat-soluble vitamins A, D, E and K — Absorption is improved if you take fatsoluble vitamins with a meal containing healthy fats. One study found that taking vitamin D with your largest meal of the day increases your blood level by 50%. — Vitamin A may be better absorbed when taken with vitamin E, but remember, Johns Hopkins University research shows doses of vitamin E over 400 units daily are associated with a higher risk of all causes of death. That may be because most vitamin E supplements contain just one of the eight forms of vitamin alpha-tocopherol. Make sure you buy vitamin E containing mixed tocopherols, or at least the one most experts think is beneficial: gamma topherol. Water-soluble vitamins C and the Bs (B6, B12, biotin, folate, niacin, pantothenic acid, riboflavin and thiamine) — Take water-soluble vitamins on an empty stomach with a glass of water. — Excessive doses of vitamin B6 can produce peripheral neuropathy, especially if your levels of B12, B2 and B9 are low. — Vitamin C increases absorption of iron from supplements and food. Your move? Increase your vitamin intake with fresh fruits and veggies, oily fish, nuts and seeds. Twice daily take half a multivitamin/multimineral that delivers the recommended levels of nutrients, not mega-doses — a balanced intake is what you’re aiming for. Get a blood test to check for vitamin deficiencies, then follow your doctor’s advice. ***

Don’t kid yourself — there’s no such thing as healthy obesity

The blue whale is the largest ocean dweller, weighing around 180 tons, and the ostrich is the largest bird — it can hit 345 pounds and still run 42 mph. Those heavyweight creatures are, well, a healthy weight. But for you, becoming a heavyweight is downright unhealthy, even if you qualify as having what some folks (not us) have called “metabolically healthy obesity.” FYI: MHO is defined as having a body mass index of 30 while meeting at least four of six normals for metabolic health: blood pressure, C-reactive protein, triglycerides, LDL and HDL cholesterol, and HbA1c, a

measure of average blood glucose. A study published in Diabetologia reveals that having a “normal” metabolic profile doesn’t exempt an obese person from increased risks for diabetes, heart diseases, strokes and respiratory diseases. Looking at 10 years’ worth of data on 381,363 individuals, the researchers found that compared to metabolicallyhealthy people without obesity, folks with MHO were 4.3 times more likely to have diabetes, 18% more likely to suffer heart attack or stroke, have a 76% higher risk of heart failure, were 28% more likely to develop respiratory disease and 19% more likely to contend with chronic obstructive pulmonary disease. Clearly, if you have MHO, you’re at risk for health problems. Our advice: If you’re overweight or obese, get weightloss support through cognitive behavioral therapy, Overeaters Anonymous or System Oz (at DocotorOZ.com). Consult a nutritionist and Dr. Mike’s www.when way.com for nutritional advice and recipes. Start a walking program heading to 10,000 steps a day. Say no to MHO. ***

Hot car hazards

In the summer of 2019, a 5-month-old child was rescued after spending almost an hour alone in a scorching-hot car in the parking lot of an Arizona Target store (it was 100 degrees outside and more than 134 degrees inside the car). Thankfully, the baby was not seriously harmed. But such circumstances don’t always end with a rescue. According to the National Highway Traffic Safety Administration, a record 53 children died from vehicular heatstroke in 2018 and 2019. And it doesn’t have to be baking outside to become dangerous inside — even if it is just 70 degrees, a closed car left in the sun can heat up to 115 degrees inside, more than enough to cause life-threatening distress. Cleveland Clinic Children’s emergency medicine physician, Dr. Purva Grover, hopes that hearing about the dangers can help people be more aware of the risk of simply forgetting that your child is in the backseat (as amazing as it sounds, that is the most common cause). Breaks in your usual routines, preoccupation and worry, and distraction — put down that cellphone — can all contribute to being forgetful. To help you stay aware, Dr. Grover suggests you put your purse, cellphone, backpack or briefcase in the back seat next to your child.


And remember, consciously deciding to leave the child in the turned off car while you just “run in for a minute” is also too risky, as is leaving the car running with the AC on. That’s ended up more than once with a stolen car and stolen baby being reported! ***

Only 7% of you are getting enough fiber

“The Seven Per-Cent Solution” is a mystery that offers intriguing insights into Sherlock Holmes’ psychology, eccentricities — and addiction to a 7% solution of cocaine. We hope you’ll find it just as entertaining to try to unravel the mystery of — and find a solution for — the fact that an average of only 7% of you are taking in enough fiber every day. An analysis of nutritional data from 14,640 adults in the National Health and Nutrition Examination Survey from 2013 to 2018 was presented at NUTRITION 2021 Live. It shows that a paltry 8.6% of guys and 11.5% of gals with diabetes — and 4.3% of guys and 8% of gals without diabetes — get an adequate intake of daily fiber. That means most of you are losing out on a powerful way to fight obesity, heart disease, diabetes, inflammation, brain fog and certain cancers. Fiber shows up in whole fruits, vegetables, nuts and seeds, 100% whole grains and cereals, and legumes — and is stripped out of processed foods like chips, white bread and pasta, pizza and premade meals. If you eat whole grains — two servings a day — and seven to nine servings of produce, you will get the 38 grams of fiber that is officially recommended on a 2,000-calorie-a-day diet. Your rewards are improved digestion, a healthier gut biome and a boost to your immune system; you’ll lose weight; inflammation decreases; and your risk for a roster of chronic diseases plummets. Now that’s a nearly 100% solution. ***

Taming your glucose levels

Greg Aiello’s “Nature Gone Wild”

brings raging bears, disastrous lightning strikes and ferocious crocodiles to your TV screen, demonstrating just how magnificent and hard to tame Mother Nature really is. That’s great fun to watch. But when it is your nature that’s untamed, it can turn seriously risky. A study by Johns Hopkins Bloomberg School of Public Health looked at how Americans who have diabetes are doing with their glucose control. Turns out that they’re going from bad to worse. From 2007 to 2010, around 57% of U.S. adults with diabetes kept their blood sugar levels in a healthy range, with an A1C of 7% or less. Now it’s about 50%. That means half of U.S. adults with diabetes are at severely increased risk for heart disease, obesity, diabetic kidney, nerve or vision complications — all health problems associated with chronically-elevated glucose levels. The study in the New England Journal of Medicine also saw that blood pressure and lipid (cholesterol and triglyceride) control have declined. These days, only 22.2% of adults with diabetes also have their lipids and blood pressure in a healthy range, a decline from 25% in 2010. This triple-whammy threatens the quality of daily life ... and longevity. The good news: You can KO these health risks with your own triplewhammy. 1. Reduce your intake of highly-processed foods, red meats and high glycemic index foods (check out “High and Low Glycemic Foods” at www.Doctor. Oz.com). 2. Achieve a healthy weight. 3. Get at least 300 minutes of aerobic activity a week. *** Mehmet Oz, M.D. is host of “The Dr. Oz Show,” and Mike Roizen, M.D. is Chief Wellness Officer Emeritus at Cleveland Clinic. To live your healthiest, tune into “The Dr. Oz Show” or visit www. sharecare.com. ©2021 Michael Roizen, M.D. and Mehmet Oz, M.D. Distributed by King Features Syndicate, Inc.

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