ANDRÉS JARAMILLO, Ph.D., HCLD/CC(ABB) Histocompatibility Laboratory Gift of Hope Organ & Tissue Donor Network 425 Spring Lake Drive Itasca, IL 60143 Tel: 630-758-2660, Fax: 630-758-2760 E-mail: ajaramillo@giftofhope.org PERSONAL DATA
Date & Place of Birth: Citizenship:
April 3, 1960. Armenia, Colombia USA & Colombia
EDUCATION & TRAINING
B.S. Department of Biological Sciences Los Andes University Bogotá, Colombia Ph.D. Department of Microbiology & Immunology University of Louisville Louisville, Kentucky Postdoctoral Fellowship The Banting & Best Department of Medical Research University of Toronto Toronto, Canada Postdoctoral Fellowship (Director-in-Training) Histocompatibility & Immunogenetics Laboratory Barnes-Jewish Hospital St. Louis, Missouri
08/1978 - 05/1982
08/1986 - 05/1991
08/1991 - 06/1994
08/1997 - 02/2001
PROFESIONAL EXPERIENCE
Director Histocompatibility Laboratory Gift of Hope Organ & Tissue Donor Network Itasca, Illinois Consulting Director Tissue Typing Laboratory University of Illinois Medical Center Chicago, Illinois Consulting Director Transplant Diagnostics Laboratory Services Life Technologies, Inc. Brown Deer, Wisconsin
11/2007 - Present
07/2010 - Present
02/2012 - Present
Andrés Jaramillo, Ph.D., HCLD/CC(ABB)
Consulting Director Histocompatibility & Immunogenetics Laboratory Rush University Medical Center Chicago, Illinois Director Histocompatibility & Immunogenetics Laboratory Rush University Medical Center Chicago, Illinois Assistant Professor Department of Pathology Rush University Medical Center Chicago, Illinois Assistant Director Histocompatibility & Immunogenetics Laboratory Barnes-Jewish Hospital St. Louis, Missouri Assistant Professor Department of Surgery Washington University School of Medicine St. Louis, Missouri Research Scientist Department of Surgery Washington University School of Medicine St. Louis, Missouri Assistant Professor Department of Microbiology & Parasitology University of Antioquia Medellín, Colombia Medical Technologist Diagnostic Immunology Laboratory San Jose Hospital Bogotá, Colombia Research Technician Colombian Institute of Immunology Foundation Bogotá, Colombia
11/2007 - 01/2012
12/2004 - 10/2007
12/2004 - 10/2007
03/2001 - 11/2004
03/2001 - 11/2004
08/1997 - 02/2001
07/1994 - 06/1997
07/1984 - 06/1986
07/1982 - 06/1984
CERTIFICATIONS
High-Complexity Clinical Laboratory Director (HCLD) American Board of Bioanalysis Discipline: Diagnostic Immunology
05/2005
Clinical Consultant (CC) American Board of Bioanalysis Discipline: Diagnostic Immunology
03/2012
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB)
Histocompatibility & Immunogenetics Laboratory Director American Society for Histocompatibility & Immunogenetics Categories: Solid Organ Transplantation: Live Donor Solid Organ Transplantation: Deceased Donor HSC/Bone Marrow Transplantation: Related Donor HSC/Bone Marrow Transplantation: Unrelated Donor Histocompatibility Testing for Other Clinical Purposes
10/2004
HONORS & AWARDS
Fulbright Fellowship U.S. Department of State Charles H. Best Fellowship University of Toronto Canadian Diabetes Association Fellowship Canadian Diabetes Association National Research Service Award U.S. National Institutes of Health ASHI Scholar Award American Society for Histocompatibility & Immunogenetics
1986 - 1991 1991 - 1993 1993 - 1994 1998 - 2001 1999
PROFESSIONAL AFFILIATIONS
American Society for Histocompatibility & Immunogenetics American Society of Transplantation The Transplantation Society American Association for Clinical Chemistry
ADMINISTRATIVE EXPERIENCE
Basic Science Committee American Society for Histocompatibility & Immunogenetics Strategic Planning Committee American Society for Histocompatibility & Immunogenetics Membership Committee American Society for Histocompatibility & Immunogenetics Director’s Training Review & Credentialing Committee American Society for Histocompatibility & Immunogenetics
2004 - 2008 2005 2005 - 2010 2006 - Present
EDITORIAL BOARDS
Editorial Board Member Journal of the Colombian Society of Dermatology & Dermatologic Surgery International Scholarly Research Network (ISRN)-Transplantation
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB)
Ad-hoc Reviewer American Journal of Transplantation Transplant Immunology The Journal of Immunology Human Immunology Biomédica
JOURNAL ARTICLES 1. Jaramillo A, Sonnenfeld G. Effects of amorphous and crystalline nickel sulfide on induction of IFN-, IFN-, and IL-2. Environmental Research 1989, 48: 275-286. 2. Jaramillo A, Sonnenfeld G. Characteristics of the inhibition of IFN- production after nickel sulfide exposure. Environmental Research 1992, 57: 88-95. 3. Jaramillo A, Sonnenfeld G. Potentiation of lymphocyte proliferative responses by nickel sulfide. Oncology 1992, 49: 396-406. 4. Jaramillo A, Bhattacherjee P, Sonnenfeld G, Paterson CA. Modulation of immune responses by cyclo-oxygenase inhibitors during intraocular inflammation. Current Eye Research 1992, 11: 571-576. 5. Jaramillo A, Sonnenfeld G. Effect of nickel sulfide on induction of IL-1 and phagocytic activity. Environmental Research 1993, 63: 16-25. 6. Rapoport MJ, Lazarus AH, Jaramillo A, Speck E, Delovitch TL. Thymic T cell anergy in autoimmune non-obese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation. Journal of Experimental Medicine 1993, 177: 1221-1226. 7. Jaramillo A, Rapoport MJ, Zipris D, Lazarus AH, Serreze DV, Leiter EH, Cyopick P, Danska JS, Delovitch TL. IL-4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in non-obese diabetic mice. Journal of Experimental Medicine 1993, 178: 87-99. 8. Jaramillo A, Gill BM, Ma L, Laupland KB, Delovitch TL. Genetic linkage of thymic T cell proliferative unresponsiveness to mouse chromosome 11 in non-obese diabetic mice: A possible role for chemokine genes. Diabetes 1995, 44: 614-619. 9. Muñoz A, Orrego JJ, Salazar M, Jaramillo D, Montoya F, Uribe O, Jaramillo A. Humoral reactivity against Borrelia burgdorferi in patients with skin and rheumatic diseases. Acta Médica 1995, 20: 257-261. 10. García D, Montoya CJ, Salgado H, Gomez RD, Patiño PJ, Botero JH, Bedoya G, Montoya F, Toro F, Vargas L, Jaramillo A, Lopez JA, Perez JE. Monitoring system for the hyperIgE syndrome. Revista Epidemiológica de Antioquia 1995, 157-166. 11. García D, Montoya CJ, Salgado H, Gomez RD, Botero JH, Patiño PJ, Montoya F, Bedoya G, Vargas L, Jaramillo A, Toro F, Lopez JA, Perez JE, Castrillon LE. Detection and management of the hyper-IgE syndrome. Revista Epidemiológica de Antioquia 1995, 167171. 12. Arreaza GA, Cameron MJ, Jaramillo A, Gill BM, Hardy D, Laupland KB, Rapoport MJ, Zucker P, Chakrabarti S, Chensue SW, Qin H-Y, Singh B, Delovitch TL. Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism. Journal of Clinical Investigation 1997, 100: 2243-2253. 13. Ramírez JR, Berberich C, Jaramillo A, Alonso C, Vélez ID. Molecular and antigenic characterization of the Leishmania (Viannia) panamensis kinetoplastid membrane protein11. Memorias Do Instituto Oswaldo Cruz 1998, 93: 247-254.
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AndrĂŠs Jaramillo, Ph.D., HCLD/CC(ABB) 14. Jaramillo A, Smith MA, Phelan D, Sundaresan, S, Trulock E, Lynch J, Cooper JD, Patterson GA, Mohanakumar T. Temporal relationship between the development of antiHLA antibodies and the development of bronchiolotis obliterans syndrome after lung transplantation. Transplantation Proceedings 1999, 31: 185-186. 15. Reznik SI, Jaramillo A, Zhang W, Naziruddin B, Patterson GA, Cooper JD, Mohanakumar T. Anti-HLA antibodies induce calcium flux and transcription of growth factors in lung epithelium: A possible mechanism for long-term lung allograft rejection. Surgical Forum 1999, L: 148-150. 16. Smith CR, Jaramillo A, Tu Y, Kaleem Z, and Mohanakumar T. Evidence for indirect T cell recognition of MHC class I antigens in a transgenic murine cardiac transplant model. Surgical Forum 1999, L: 397-399. 17. Jaramillo A, Smith MA, Phelan D, Sundaresan, S, Trulock EP, Lynch J, Cooper JD, Patterson GA, Mohanakumar T. Development of ELISA-detected anti-HLA antibodies precedes the development of bronchiolitis obliterans syndrome and correlates with progressive decline in pulmonary function after lung transplantation. Transplantation 1999, 67: 1155-1161. 18. Reznik SI, Jaramillo A, Zhang L, Patterson GA, Cooper JD, Mohanakumar T. Anti-HLA antibody binding to HLA class I molecules induces proliferation of airway epithelial cells: A potential mechanism for bronchiolitis obliterans syndrome. Journal of Thoracic & Cardiovascular Surgery 2000, 119: 39-45. 19. Olack B, Manna P, Jaramillo A, Steward N, Swanson C, Kaesberg DM, Poindexter N, Howard T, Mohanakumar T. Indirect recognition of porcine SLA class I molecules expressed on islets by human CD4+ T lymphocytes. Journal of Immunology 2000, 165: 1294-1299. 20. Smith CR, Jaramillo A, Duffy BF, Mohanakumar T. Airway epithelial cells damage mediated by antigen-specific T cells: Implications in lung allograft rejection. Human Immunology 2000, 61: 985-992. 21. Olack BJ, Jaramillo A, Zhang L, Swanson C, Rayan K, Goodnight DM, Howard T, Mohanakumar T. The role of indirect antigen recognition in islet xenograft rejection. Transplantation Proceedings 2001, 33: 784-785. 22. Jaramillo A, Naziruddin B, Zhang L, Reznik SI, Smith MA, Trulock EP, Patterson GA, Mohanakumar T. Activation of human airway epithelial cells by non-HLA antibodies developed after lung transplantation: A potential etiologic factor for bronchiolitis obliterans syndrome. Transplantation 2001, 71: 966-976. 23. Smith CR, Jaramillo A, Tu Y, Kaleem Z, Mohanakumar T. CD4+ T cell recognition of a single mismatched HLA-A2 transgenic molecule through the indirect antigen presentation pathway induces rejection of murine cardiac allografts. Transplantation 2001, 71: 16401648. 24. Nguyen TQ, Jaramillo A, Thompson RW, Dintzis S, Oppat WF, Allen BT, Sicard GA, Mohanakumar T. Increased expression of HDJ-2 (hsp40) in carotid artery atherosclerosis: A novel heat shock protein associated with luminal stenosis and plaque ulceration. Journal of Vascular Surgery 2001, 33: 1065-1071. 25. Jaramillo A, Reznik RI, SivaSai KSR, Womer KL, Sayegh MH, Trulock EP, Patterson GA, Monahakumar T. Indirect allorecognition of mismatched donor-derived HLA class II peptides in lung transplant recipients with bronchiolitis obliterans syndrome. American Journal of Transplantation 2001, 1: 228-235.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 26. Smith CR, Jaramillo A, Lu KC, Higuchi T, Kaleem Z, Mohanakumar T. Prevention of obliterative airway disease in HLA-A2-transgenic tracheal allografts by neutralization of TNF. Transplantation 2001, 72: 1512-1518. 27. Smith CR, Jaramillo A, Poindexter NJ, Steward NS, Lu KC, Brennan DC, Singer GG, Miller BW, Jendrisak MD, Shenoy S, Lowell JA, Howard TK, Mohanakumar T. In vitro T cell proliferation from kidney transplant biopsies with unremarkable pathology: New strategies for an old problem. Transplantation 2002, 73: 142-145. 28. Smith MA, Jaramillo A, SivaSai KSR, Naziruddin B, Kaleem Z, Patterson GA, Mohanakumar T. Indirect recognition and antibody production against a single mismatched HLA-A2-transgenic molecule precede the development of obliterative airway disease in murine heterotopic tracheal allografts. Transplantation 2002, 73: 186-193. 29. Higuchi T, Jaramillo A, Kaleem Z, Patterson GA, Mohanakumar T. Different kinetics of obliterative airway disease development induced by CD4+ and CD8+ T cells in murine heterotopic tracheal allografts. Transplantation 2002, 74: 646-651. 30. Jaramillo A, Olack BJ, Benshoff ND, Kaleem Z, Swanson CJ, Lowell JA, Mohanakumar T. Rejection of porcine islet xenografts mediated by CD4+ T cells activated through the indirect antigen recognition pathway. Xenotransplantation 2002, 9: 393-401. 31. Jaramillo A, Majumder K, Manna PP, Fleming TP, Doherty G, DiPersio JF, Mohanakumar T. Identification of HLA-A3-restricted CD8+ T cell epitopes derived from mammaglobin-A, a tumor-associated antigen of human breast cancer. International Journal of Cancer 2002, 102: 499-506. 32. Jaramillo A, Lu KC, Lecha RL, Schuessler RB, Aloush A, Trulock EP, Mendeloff EN, Huddleston CB, Patterson GA, Mohanakumar T. IL-6 and IFN- gene polymorphisms in the development of bronchiolitis obliterans syndrome after lung transplantation. Transplantation 2002, 74: 1297-1302. 33. Jaramillo A, Lu KC, Mendeloff EN, Huddleston CB, Sweet SC, Patterson GA, Mohanakumar T. Concomitant allorecognition of mismatched donor HLA class I- and class II-derived peptides in pediatric lung transplant recipients with bronchiolitis obliterans syndrome. Journal of Heart & Lung Transplantation 2003, 22: 35-43. 34. Sreenarasimhaiah J, Jaramillo A, Crippin J, Lisker-Melman M, Chapman WC, Mohanakumar T. Lack of optimal T cell reactivity to hepatitis C virus is associated with the development of fibrosis/cirrhosis during chronic hepatitis. Human Immunology 2003, 64: 224-230. 35. Jaramillo A, Sreenarasimhaiah J, Crippin J, Lisker-Melman M, Chapman WC, Mohanakumar T. Concomitant augmentation of type 1 CD4+ and CD8+ T cell responses during successful IFN- and ribavirin treatment for chronic hepatitis C virus infection Human Immunology 2003, 64: 497-504. 36. Jaramillo A, Smith CR, Maruyama T, Zhang L, Patterson GA, Mohanakumar T. Anti-HLA class I antibody binding to airway epithelial cells induces production of fibrogenic growth factors and apoptotic cell death: A possible mechanism for bronchiolitis obliterans syndrome. Human Immunology 2003, 64: 521-529. 37. Manna PP, Jaramillo A, Majumder K, Campbell LG, Fleming TP, Dietz JR, DiPersio JF, Mohanakumar T. Generation of CD8+ cytotoxic T lymphocytes against breast cancer cells by stimulation with mammaglobin-A-pulsed dendritic cells. Breast Cancer Research & Treatment 2003, 79: 133-136.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 38. Yang J, Jaramillo A, Liu W, Olack B, Yoshimura Y, Joyce S, Kaleem Z, Mohanakumar T. Chronic rejection of murine cardiac allografts discordant at the H13 minor histocompatibility antigen correlates with the generation of H13-specific CD8+ cytotoxic T cells. Transplantation 2003, 76: 84-91. 39. Dabil H, Kaplan HJ, Duffy BF, Phelan DL, Mohanakumar T, Jaramillo A. Association of the HLA-DR15/HLA-DQ6 haplotype with development of choroidal neovascular lesions in presumed ocular histoplasmosis syndrome. Human Immunology 2003, 64: 960-964. 40. Fernández FG, Jaramillo A, Chen C, Liu DZ, Tung T, Patterson GA, Mohanakumar T. Airway epithelium is the primary target of allograft rejection in murine obliterative airway disease. American Journal of Transplantation 2004, 4: 319-325. 41. Shi R, Yang J, Jaramillo A, Steward NS, Aloush A, Trulock EP, Patterson, GA, Suthanthiran M, Mohanakumar T. Correlation between IL-15 and granzyme B expression and acute lung allograft rejection. Transplant Immunology 2004, 12: 103-108. 42. Ramachandran S, Jaramillo A, Xu X-C, McKane B, Chapman WC, Mohanakumar T. Human immune responses to porcine endogenous retrovirus-derived peptides presented naturally in the context of porcine and human MHC class I molecules: Implications in xenotransplantation of porcine organs. Transplantation 2004, 77: 1580-1588. 43. Narayanan K, Jaramillo A, Phelan DL, Mohanakumar T. Pre-exposure to sub-saturating concentrations of anti-HLA class I antibodies confers resistance to endothelial cells against antibody/complement-mediated lysis by regulating Bad through the phosphatidylinositol 3-kinase/Akt pathway. European Journal of Immunology 2004, 34: 2303-2312. 44. Yang J, Jaramillo A, Shi R, Kwok WW, Mohanakumar T. In vivo biotinylation of the MHC class II/peptide complex by co-expression of BirA enzyme for the generation of MHC class II/tetramers. Human Immunology 2004, 65: 692-699. 45. Narayanan K, Jaramillo A, Benshoff ND, Campbell LG, Fleming TP, Dietz JR, Mohanakumar T. Response of established human breast tumors to vaccination with mammaglobin-A cDNA. Journal of the National Cancer Institute 2004, 96: 1388-1396. 46. Jaramillo A, Narayanan K, Campbell LG, Benshoff ND, Lybarger L, Hansen TH, Fleming TP, Dietz JR, Mohanakumar T. Recognition of HLA-A2-restricted mammaglobin-A-derived epitopes by CD8+ cytotoxic T lymphocytes from breast cancer patients. Breast Cancer Research & Treatment 2004, 88: 29-41. 47. Fox IK, Jaramillo A, Hunter DA, Rickman SR, Mohanakumar T, Mackinnon SE. Prolonged cold preservation of nerve allografts. Muscle & Nerve 2005, 31: 59-69. 48. Higuchi T, Maruyama T, Jaramillo A, Mohanakumar T. Induction of obliterative airway disease in murine tracheal allografts by CD8+ CTLs recognizing a single minor histocompatibility antigen. Journal of Immunology 2005, 174: 1871-1878. 49. Campbell LG, Ramachandran S, Liu W, Shipley JM, Itohara S, Rogers JG, Moazami N, Senior RM, Jaramillo A. Different roles of MMP-2 and MMP-9 in the pathogenesis of cardiac allograft rejection. American Journal of Transplantation 2005, 5: 517-528. 50. Fernández FG, Campbell LG, Liu W, Shipley JM, Itohara S, Patterson GA, Senior RM, Mohanakumar T, Jaramillo A. Inhibition of obliterative airway disease development in murine tracheal allografts by MMP-9-deficiency. American Journal of Transplantation 2005, 5: 671-683. 51. Fernández FG, Jaramillo A, Ewald G, Rogers J, Pasque MK, Mohanakumar T, Moazami N. Blood transfusions decrease the incidence of acute rejection in cardiac allograft recipients. Journal of Heart & Lung Transplantation 2005, 24: S255-S261.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 52. Brenner MJ, Mackinnon SE, Rickman SR, Jaramillo A, Tung TH, Hunter DA, Mohanakumar T. FK506 and anti-CD40 ligand in peripheral nerve allotransplantation. Restorative Neurology & Neuroscience 2005, 23: 237-249. 53. Jaramillo A, Maruyama T, Narayanan K, Higuchi T, Mohanakumar T. Induction of obliterative airway disease by anti-HLA class I antibodies. American Journal of Transplantation 2005, 5: 2126-2134. 54. Eaton VL, Lerret NM, Velásquez-Lopera MM, John R, Caicedo M, DeCresce RP, Jaramillo A. Enhancement of allograft survival and modulation of T cell alloreactivity induced by inhibition of MMP/ADAM enzymatic activity. American Journal of Transplantation 2008, 8: 507-516. 55. Velásquez-Lopera MM, Eaton VL, Lerret NM, Correa LA, DeCresce RP, García LF, Jaramillo A. Induction of transplantation tolerance by allogeneic donor-derived CD4+CD25+Foxp3+ regulatory T cells. Transplant Immunology 2008, 19: 127-135. 56. Kaul DR, Taranto S, Alexander C, Covington S, Marvin M, Nowicki M, Orlowski J, Pancoska C, Pruett TL, Ison MG, OPTN/UNOS HTLV Donor Screening Advisory Group. Donor screening for human T-cell lymphotropic virus-1/2: Changing paradigms for changing testing capacity. American Journal of Transplantation 2009, 9: 1-7. 57. Howard MS, Yepes MM, Maldonado-Estrada JG, Villa-Robles E, Jaramillo A, Botero JH, Patiño PJ, Hashimoto T, Abreu-Vélez AM. Broad histopathologic patterns of non-glabrous skin and glabrous skin from patients with a new variant of endemic pemphigus foliaceus. Journal of Cutaneous Pathology 2010, 37: 222-230. 58. Lerret NM, Rogozinska M, Jaramillo A, Marzo AL. Adoptive transfer of Mammaglobin-A epitope-specific CD8+ T cells combined with low-dose total body irradiation eradicates breast tumors. The Public Library of Science ONE. Submitted. 59. Du Z, Weidner JG, Chang A, Kunnavakkam R, Aggarwal N, Jaramillo A, Josephson MA, Marino SR. Pre-transplant donor-specific HLA antibodies and positive B-cell flow cytometric crossmatch predict long-term kidney allograft loss. Tranplantation. Submitted. 60. Theodoropoulos N, Jaramillo A, Penugonda S, Wasik C, Brooks K, Ladner DP, Jendrisak MD, Ison MG. Improving Syphilis Screening in Deceased Organ Donors. American Journal of Transplantation. Submitted. 61. Jendrisak MD, Salil Kalra S, Jendrisak A, Harmon M, Skolek R, Jaramillo A, Schwartz M, Cimbulak D. Application of the donor kidney biopsy audit score to clarify histopathology findings impacting organ utilization for transplantation. American Journal of Transplantation. In preparation. 62. Jaramillo A, Labuda B, Freedom D, Magas D. Virtual crossmatch using luminex singleantigen beads: An accurate method to predict the flow cytometric crossmatch outcome & strength. In preparation. 63. Jaramillo A, Jendrisak MD, Labuda B, Freedom D, Magas D, Jennings LJ, Kanangat S, Lower F, Susskind B, Marino SR, Gaitonde S, Tambur AR. Significant increase of deceased donor renal transplants in highly sensitized patients by implementation of the virtual crossmatch. In preparation. INVITED ARTICLES 1. Jaramillo A, Gill BM, Delovitch TL. Insulin-dependent diabetes mellitus in the non-obese diabetic mouse: A disease mediated by T cell anergy. Life Sciences 1994, 55: 1163-1177. 2. Vargas L, Jaramillo A. The chemokines: A new family of regulatory cytokines of the inflammation process. Acta Médica 1995, 20: 100-107. Page 8 of 19
Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 3. Bedoya LR, Ramírez BE, Caraballo D, Jaramillo A. Exercise-mediated immune regulation: Interaction between heat shock proteins and the endocrine-immune system. Acta Médica 1996, 21: 139-145. 4. Jaramillo A, Phelan D, Mohanakumar T. New aspects in histocompatibility testing: DNA sequence-based typing. Barnes-Jewish Hospital: Laboratory Medicine Newsletter 1999, 5: 1-4. 5. Mohanakumar T. Xu X-C, Jaramillo A. Regulation of xenoreactive CD4+ T-cell anergy by suppressor CD8+CD28 T cells. Transplantation 2000, 69: 1233-1234. 6. Jaramillo A, Fernández FG, Kuo EY, Trulock EP, Patterson GA, Mohanakumar T. Immune mechanisms in the pathogenesis of bronchiolitis obliterans syndrome after lung transplantation. Pediatric Transplantation 2005, 9: 84-93. 7. Jaramillo A, Turon J, Labuda B, Freedom D, Magas D. Single antigen beads are an accurate predictor of the flow cytometry crossmatch outcome & strength. Visuals of the One Lambda’s Clinical Histocompatibility Workshop 2009: 10-12. 8. Jaramillo A, Turon J, Labuda B, Freedom D, Magas D. Significant increase of kidney transplants in highly sensitized patients by implementation of the virtual crossmatch. Visuals of the One Lambda’s Clinical Histocompatibility Workshop 2011: 10-13. BOOK CHAPTERS 1. Rapoport MJ, Zipris D, Lazarus AH, Jaramillo A, Delovitch TL. Altered T-cell development and function in prediabetic non-obese diabetic mice: Mechanisms and relevance to disease. In: HLA 1991. Proceedings of the 11th International Histocompatibility Workshop & Conference. Editors: Tsuji K, et al. Oxford University Press, New York, New York. 1992: C1.112-121. 2. Delovitch TL, Jaramillo A, Rapoport MJ, Laupland KB, Zipris D, Smith S, Kelvin D, Gill BM. Anti-inflammatory role of IL-4 and Th2 cells in the protection against insulindependent diabetes mellitus. In: Diabetes 1994. Proceedings of the 15th International Congress of Immunology & Diabetes. Editors: Baba S & Kaneko T. Elsevier Science Publishers, New York, New York. 1995: 203-209. 3. Jaramillo A, Mohanakumar T. Clinical significance of the monocyte crossmatch technique in kidney transplantation. In: Guidelines for Clinical Histocompatibility Practice. Editors: ASHI Council. Lenexa, Kansas. 1999: 65-69. 4. Reznik SI, Jaramillo A, Mohanakumar T. Induction of transplant immunity: An overview of the initial immune events after allotransplantation. In: Transplantation Immunobiology. Editors: Duquesnoy RJ & Li Y. Beijing, China. 2000: 141-154. 5. Xu X-C, Jaramillo A, Mohanakumar T. Minor histocompatibility and non-MHC antigens. In: Transplantation Immunobiology. Editors: Duquesnoy RJ & Li Y. Beijing, China. 2000: 493-507. 6. Lu KC, Jaramillo A, Mohanakumar T. Tissue and solid organ allograft rejection. In: Samter’s Immunologic Diseases. Editors: Austen KF, et al. Lippincott Williams & Wilkins, Baltimore, Maryland. 2001: 1121-1132. 7. Fernández FG, Jaramillo A, Mohanakumar T. Epithelial cell biology in organ transplantation. In: Immunobiology of Organ Transplantation. Editors: Wilkes DS & Burlingham W. Kluwer Academic/Plenum Publishers, New York, NY. 2004: 607-619. 8. Jaramillo A, Fernández FG, Rugeles-López MT. Immune responses to allografts. In: Immunology: An Active Science. First Edition. Editors: Rugeles-López MT & PatiñoGrajales PJ. Biogenesis, Medellín, Colombia. 2004: 435-448. Page 9 of 19
Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 9. Marino SG, Jaramillo A, Fernández-Viña MA. The human major histocompatibility complex and DNA-based typing of human leukocyte antigens for transplantation. In: Handbook of Human Immunology. Second Edition. Editors: Donnenberg AD & O'Gorman M. CRC Press-Taylor & Francis Group, LLC, New York, New York. 2008: 541-564. 10. Jaramillo A, Rugeles-López MT. Immune responses to allografts. In: Immunology: An Active Science. Second Edition. Editors: Rugeles-López MT, et al. University of Antioquia, Medellín, Colombia. 2009: 455-469. ABSTRACTS 1. Jaramillo A, Sonnenfeld G. Immunotoxic effects of crystalline nickel sulfide. Meeting of the International Society for Interferon Research. San Francisco, California. 1990. 2. Bhattacherjee P, Jaramillo A, Sonnenfeld G, Paterson CA. Modulation of immune responses by cyclo-oxygenase inhibitors during intraocular inflammation. Meeting of the Association for Research in Vision & Ophthalmology. Tampa, Florida. 1992. 3. Rapoport MJ, Jaramillo A, Lazarus AH, Delovitch TL. Defective thymic T cell signalling in prediabetic NOD mice. Meeting of the Canadian Society for Immunology. Mont Roland, Canada. 1992. 4. Delovitch TL, Rapoport MJ, Jaramillo A, Lazarus AH. Defective thymic T cell signalling in prediabetic NOD mice. International congress of Immunology. Budapest, Hungary. 1992. 5. Jaramillo A, Rapoport MJ, Zipris D, Lazarus AH, Serreze DV, Leiter EH, Cyopick P, Delovitch TL. IL-4 reverses T cell unresponsiveness and prevents the onset of diabetes in NOD mice. International Congress of Immunology & Diabetes. Orlando, Florida. 1993. 6. Jaramillo A, Laupland KB, Gill BM, Van Houten N, Budd RC, Delovitch TL. Thymic T cell anergy in NOD mice is reversed by costimulation via CD28. Keystone symposia. Keystone, Colorado. 1994. 7. Forero C, Vargas L, García D, Montoya F, Patiño PJ, Jaramillo A. Reduced L-selectin expression on granulocytes from patients with hyper-IgE syndrome. AAAAI/AAI/CIS joint meeting. San Francisco, California. 1997. 8. Vargas L, Patiño PJ, García D, Rodriguez MF, Forero C, Montoya F, Jaramillo A. Effect of mononuclear cell culture supernatants from patients with hyper-IgE syndrome and allergic asthma on chemotaxis, oxidative metabolism, and CD11b/CD18 expression of human granulocytes. AAAAI/AAI/CIS joint meeting. San Francisco, California. 1997. 9. Abreu-Vélez AM, Maldonado JG, Jaramillo A, Patiño PJ, Prada S, Leon-Herrera W, Botero J, Warfvinge G, Montoya F. Description of an unusual focus of endemic pemphigus foliaceus in a rural area of El Bagre, Colombia. Meeting of the Federation of American Societies for Experimental Biology. San Francisco, California. 1998. 10. Abreu-Vélez AM, Maldonado JG, Jaramillo A, Botero J, Montoya F. Description of an unusual focus of endemic pemphigus foliaceus in a rural area of the municipality of El Bagre, Colombia, South America. Meeting of the Society for Investigative Dermatology. Cologne, Germany. 1998. 11. Abreu-Vélez AM, Maldonado JG, Jaramillo A, Patiño PJ, Prada S, Leon-Herrera W, Montoya F. Immunological characterization of a unique focus of endemic pemphigus foliaceus in the rural area of El Bagre, Colombia. Meeting of the Society for Investigative Dermatology. Cologne, Germany. 1998.
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AndrĂŠs Jaramillo, Ph.D., HCLD/CC(ABB) 12. Jaramillo A, Naziruddin B, Smith M, Phelan D, Sundaresan S, Trulock E, Lynch J, Cooper J, Patterson GA, Mohanakumar T. Correlation of antibodies to HLA with bronchiolitis obliterans after lung transplantation. World Congress of the Transplantation Society. Montreal, Canada. 1998. 13. Jaramillo A, Smith M, Phelan D, Sundaresan S, Trulock EP, Lynch J, Cooper JD, Patterson GA, Mohanakumar T. Correlation of development of ELISA-detected IgG antiHLA antibodies with the development of bronchiolitis obliterans syndrome after lung transplantation. Meeting of the American Society for Histocompatibility & Immunogenetics. Vancouver, Canada. 1998. 14. Reznik SI, Jaramillo A, Zhang WJ, Patterson GA, Cooper JD, Mohanakumar T. Anti-HLA antibodies stimulate phosphorylation and proliferation of lung epithelial cells: A possible mechanism for chronic lung allograft rejection. Meeting of the International Society for Heart & Lung Transplantation. San Francisco, California. 1999. 15. Reznik SI, Jaramillo A, Patterson GA, Cooper JD, Mohanakumar T. Indirect allorecognition of HLA class II allopeptides in lung allograft recipients. Meeting of the International Society for Heart & Lung Transplantation. San Francisco, California. 1999. 16. Reznik SI, Jaramillo A, Zhang W, Patterson G, Cooper J, Mohanakumar T. Proliferation of airway epithelial cells secondary to anti-HLA antibody binding: A potential mechanism for bronchiolitis obliterans syndrome. Meeting of the American Association for Thoracic Surgery. New Orleans, Louisiana. 1999. 17. Reznik SI, Jaramillo A, Sayegh M, Patterson GA, Mohanakumar T. Sensitization against donor mismatched HLA class II peptides in lung transplant recipients with bronchiolitis obliterans syndrome. Meeting of the American Society of Transplantation. Chicago, Illinois. 1999. 18. Jaramillo A, Naziruddin B, Smith MA, Phelan D, Trulock EP, Lynch JP, Cooper JD, Patterson GA, Mohanakumar T. Development of anti-airway epithelial cell specific antibodies in lung transplant recipients with bronchiolitis obliterans syndrome. Meeting of the American Society of Transplantation. Chicago, Illinois. 1999. 19. Olack B, Duffy B, Phelan D, Jaramillo A, Brennan D, Howard T, Mohanakumar T. HLA antibody development following islet transplantation. World Congress of the International Pancreas & Islet Transplant Association. Sydney, Australia. 1999. 20. Smith C, Jaramillo A, Kaleen Z, Mohanakumar T. Indirect recognition of MHC class I antigens elicits allograft rejection in a transgenic murine cardiac transplant model. Basic Sciences Symposium of the Transplantation Society. Monterey, California. 1999. 21. Jaramillo A, Smith MA, Cooper J, Patterson GA, Mohanakumar T. Characterization of airway epithelial cell-specific non-HLA antibodies developed in lung transplant recipients with bronchiolitis obliterans syndrome (BOS): Implications in BOS pathogenesis. Basic Sciences Symposium of the Transplantation Society. Monterey, California. 1999. 22. Jaramillo A, Naziruddin B, Zhang L, Phelan D, Smith MA, Trulock EP, Patterson GA, Mohanakumar T. Biochemical and biological characterization of non-HLA anti-airway epithelial cell antibodies developed in lung transplant recipients with bronchiolitis obliterans syndrome. Meeting of the American Society for Histocompatibility & Immunogenetics. New Orleans, Louisiana. 1999. 23. Smith C, Jaramillo A, Tu Y, Kaleem Z, Mohanakumar T. Vascularized cardiac allografts from HLA-A2 transgenic animals are rejected by syngeneic recipients primarily by indirect recognition of HLA-A2 antigen by CD4+ T cells. Transplant Fellows Research Symposium. Orlando, Florida. 1999.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 24. Jaramillo A, Lu KC, Zhang L, Mohanakumar T. Binding of anti-HLA class I antibodies to airway epithelial cells induces activation and growth factor production and indirectly upregulates lung fibroblast proliferation. Meeting of the American Society of Transplantation. Chicago, Illinois. 2000. 25. Jaramillo A, Zhang L, Trulock EP, Patterson GA, Mohanakumar T. Anti-HLA antibodymediated activation of airway epithelial cells induces the production of several fibrogenic growth factors followed by apoptotic cell death. Meeting of the American Society of Transplantation. Chicago, Illinois. 2001. 26. Jaramillo A, Jarrett D, Santoro R, Mohanakumar T. Intra-tracheal instillation of allogeneic spleen cells induce early signs of obliterative bronchiolitis associated with expression of PCNA and IGF-1 in situ. Meeting of the Federation of American Societies for Experimental Biology. Orlando, Florida. 2001. 27. Jaramillo A, Reznik RI, SivaSai KSR, Womer KL, Sayegh MH, Trulock EP, Patterson GA, Monahakumar T. Indirect allorecognition of mismatched donor HLA class II peptides in lung transplant recipients with bronchiolitis obliterans syndrome. Basic Sciences Symposium of the Transplantation Society. Bern, Switzerland. 2001. 28. Jaramillo A, Lu W, Smith CR, Kaleem Z, Monahakumar T. The role of MMP-2 and MMP9 during the development of obliterative airway disease after heterotopic tracheal transplantation in mice. Basic Sciences Symposium of the Transplantation Society. Bern, Switzerland. 2001. 29. Jaramillo A, Lu W, Mohanakumar T. Up-regulation of MMP-2 and MMP-9 production during acute rejection of murine cardiac allografts. American Transplant Congress. Washington, DC. 2002. 30. Jaramillo A, Lu W, Mohanakumar T. MMP-2 and MMP-9 up-regulation during the development of obliterative airway disease in murine tracheal allografts. American Transplant Congress. Washington, DC. 2002. 31. Jaramillo A, Lu W, Campbell LG, Shipley JM, Senior RM, Itohara S. Prolongation of cardiac allograft survival by abrogation of MMP-2 activity. American Transplant Congress. Washington, DC. 2003. 32. Ramachandran S, Jaramillo A, Chapman WC, Mohanakumar T. Porcine endogenous retrovirus-derived peptides are presented naturally in the context of porcine and human MHC class I molecules. Basic Sciences Symposium of the Transplantation Society. Keystone, Colorado. 2003. 33. Fernández FG, MacKane B, Marshbank S, Jaramillo A, Patterson GA, Mohanakumar T. Inhibition of obliterative airway disease development by costimulatory molecule blockade using anti-CD40L alone or in combination with donor bone marrow following heterotopic murine tracheal transplantation. Basic Sciences Symposium of the Transplantation Society. Keystone, Colorado. 2003. 34. Fernández FG, Jaramillo A, Chen C, Tung T, Patterson GA, Mohanakumar T. Epithelial cell repopulation of recipient origin markedly attenuates obliterative airway disease lesions in murine orthotopic tracheal allografts. Basic Sciences Symposium of the Transplantation Society. Keystone, Colorado. 2003. 35. Fernández FG, Campbell LG, Chen C, Lu W, Shipley JM, Senior RM, Itohara S, Jaramillo A. Inhibition of obliterative airway disease development in murine tracheal allografts by MMP-9-deficiency. Basic Sciences Symposium of the Transplantation Society. Keystone, Colorado. 2003.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 36. Jaramillo A, Lu W, Campbell LG, Shipley JM, Senior RM, Itohara S. Prolongation of cardiac allograft survival by abrogation of MMP-2 activity. Basic Sciences Symposium of the Transplantation Society. Keystone, Colorado. 2003. 37. Maruyama T, Jaramillo A, Patterson GA, Mohanakumar T. The role of humoral immune mechanisms in the development of obliterative airway disease after heterotopic tracheal allograft transplantation. Basic Sciences Symposium of the Transplantation Society. Keystone, Colorado. 2003. 38. Thompson C, Phelan D, Jaramillo A, Ceriotti C, Chapman W, Mohanakumar T. Transplant test sensitivity: How much is necessary? Meeting of the American Society for Histocompatibility & Immunogenetics. Miami, Florida. 2003. 39. Fernández FG, Jaramillo A, Liu D, Chen C, Mohanakumar T. Development of obliterative airway disease after heterotopic tracheal transplantation is abrogated by TNF--deficiency in either donor or recipient. Meeting of the American Society for Histocompatibility & Immunogenetics. Miami, Florida. 2003. 40. Fernández FG, Jaramillo A, Chen C, Tung T, Patterson GA, Mohanakumar T. Airway epithelium is the primary target of tracheal allograft rejection in obliterative airway disease. Meeting of the American Society for Histocompatibility & Immunogenetics. Miami, Florida. 2003. 41. Fernández FG, McKane B, Jaramillo A, Patterson GA, Mohanakumar T. Prevention of obliterative airway disease through tolerance induction following CD40 costimulatory blockade in combination with donor bone marrow cell infusion. Meeting of the American Society for Histocompatibility & Immunogenetics. Miami, Florida. 2003. 42. Ramachandran S, Jaramillo A, Chapman WC, Mohanakumar T. Porcine endogenous retrovirus significantly contributes peptide epitopes for SLA and HLA class I molecules: Implications for xenotransplantation. Meeting of the American Society for Histocompatibility & Immunogenetics. Miami, Florida. 2003. 43. Fernández FG, Campbell LG, Chen C, Senior RM, Itohara S, Mohanakumar T, Jaramillo A. Abrogation of obliterative airway disease in murine tracheal allografts in MMP-9deficient mice. Meeting of the American Society for Histocompatibility & Immunogenetics. Miami, Florida. 2003. 44. Jaramillo A, Lu W, Campbell LG, Shipley JM, Senior RM, Itohara S. Prolongation of cardiac allograft survival in MMP-2-deficient mice. Meeting of the American Society for Histocompatibility & Immunogenetics. Miami, Florida. 2003. 45. Fernández FG, Jaramillo A, Ewald G, Rogers J, Pasque MK, Mohanakumar T, Moazami N. Negative association between transfusions and acute cardiac allograft rejection. Meeting of the International Society for Heart & Lung Transplantation. San Francisco, California. 2004. 46. Fernández FG, Campbell LG, Liu W, Shipley JM, Itohara S, Patterson GA, Senior RM, Mohanakumar T, Jaramillo A. Inhibition of obliterative airway disease development in murine tracheal allografts by MMP-9-deficiency. Meeting of the International Society for Heart & Lung Transplantation. San Francisco, California. 2004. 47. Fox IK, Hunter DA, Jaramillo A, Mackinnon SE, Mohanakumar T, Rickman SR. The effect of cold preservation on nerve allografts. Meeting of the American Society of Plastic Surgeons, Philadelphia, Pennsylvania, 2004. 48. Fox IK, Jaramillo A, Mohanakumar T, Hunter DA, Mackinnon SE. Effect of cold preservation on nerve allografts. Meeting of the American Society for the Peripheral Nerve, Palm Springs, California, 2004.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 49. Jaramillo A, Campbell LG, Shipley JM, Senior RM, Itohara S. Different roles of MMP-2 and MMP-9 in the pathogenesis of cardiac allograft rejection. Meeting of the American Society for Histocompatibility & Immunogenetics. San Antonio, Texas. 2004. 50. Jaramillo A, Narayanan K, Campbell LG, Steward NS, Trulock EP, Paterson GA, Mohanakumar T. Lack of chronic lung allograft rejection is associated with the expansion of regulatory CD4+CD25+ and CD4+CD28 T cells and a predominant Th2 alloreactivity. Meeting of the American Society for Histocompatibility & Immunogenetics. San Antonio, Texas. 2004. 51. Wetter L, Phelan DL, Ceriotti, C, Jendrisak M, Jaramillo A, Mohanakumar T. Risk of renal allograft rejection predicted using IFN- ELISPOT assay. Meeting of the American Society for Histocompatibility & Immunogenetics. San Antonio, Texas. 2004. 52. Jennemann J, Phelan DL, Ceriotti C, Jaramillo A, Chapman WC, Mohanakumar T. NonHLA: A potential cause for rejection in renal transplantation. Meeting of the American Society for Histocompatibility & Immunogenetics. San Antonio, Texas. 2004. 53. Jaramillo A, Coon JS, DeCresce RP. Different roles of MMP-2 and MMP-9 in the pathogenesis of cardiac allograft rejection. Rush University Forum for Research & Clinical Investigation. Chicago, Illinois. 2005. 54. Eaton VL, Velásquez-Lopera MM, Caicedo M, Coon JS, DeCresce RP, Jaramillo A. Prolongation of cardiac allograft survival and modulation of T cell alloreactivity induced by MMP inhibition. Rush University Forum for Research & Clinical Investigation. Chicago, Illinois. 2006. 55. Velásquez-Lopera MM, Eaton VL, Coon JS, DeCresce RP, García LF, Jaramillo A. Inhibition of CD4+ and CD8+ T cell alloreactivity by allogeneic donor-derived regulatory CD4+CD25+ T cells. Rush University Forum for Research & Clinical Investigation. Chicago, Illinois. 2006. 56. Velásquez-Lopera MM, Vargas A, Arellano G, Correa LA, Wolff JC, Villamizar JC, Jaramillo A, García LF, Cuellar-Ambrosi F. Immunohistochemical evaluation of infiltrating cells (CD4+, CD8+, and CD56+) and Langerhans cells in skin of graft-versus-host disease patients. European Hematology Association Congress. Amsterdam, Netherlands, 2006. 57. Eaton VL, Velásquez-Lopera MM, Caicedo M, DeCresce RP, Jaramillo A. Prolongation of cardiac allograft survival and modulation of T cell alloreactivity induced by inhibition of MMP activity. Meeting of the American Society for Histocompatibility & Immunogenetics. San Diego, California. 2006. 58. Velásquez-Lopera MM, Eaton VL, DeCresce RP, García LF, Jaramillo A. Inhibition of CD4+ and CD8+ T cell alloreactivity by allogeneic donor-derived regulatory CD4+CD25+ T cells. Meeting of the American Society for Histocompatibility & Immunogenetics. San Diego, California. 2006. 59. Braun CM, Jaramillo A. Optimization of sequence-based HLA typing using the SeCore sequencing kits with the POP-7 polymer. Meeting of the American Society for Histocompatibility & Immunogenetics. San Diego, California. 2006. 60. Velásquez-Lopera MM, Eaton VL, Lerret NM, Correa LA, DeCresce RP, García LF, Jaramillo A. Induction of transplantation tolerance by allogeneic donor-derived CD4+CD25+Foxp3+ regulatory T cells. Meeting of the American Society for Histocompatibility & Immunogenetics. Minneapolis. Minnesota. 2007.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 61. Braun CM, Prod MH, Oppermann M, Piggott S, Jackson AN, Sheldon S, Cano P, Fernández-Viña M, Jaramillo A. Report of a new HLA-DRB1*03 allele escaping detection by high-resolution sequence-specific priming and sequence-based typing. Meeting of the American Society for Histocompatibility & Immunogenetics. Minneapolis. Minnesota. 2007. 62. Piggott S, Prod MH, Oppermann M, Braun CM, Jackson AN, Jensik S, Mital D, Jaramillo A. Successful kidney transplantation in the presence of solid phase-detected donorspecific antibodies with negative flow cytometric crossmatches. Meeting of the American Society for Histocompatibility & Immunogenetics. Minneapolis. Minnesota. 2007. 63. John R, Jaramillo A, Mozes M, Saltzberg S, Jensik S, Schwartz M. C4d: A valuable marker of humoral rejection in the early and late post-transplant period. Meeting of the American Society of Nephrology. San Francisco, California. 2007. 64. Velásquez-Lopera MM, Eaton VL, Lerret NM, Correa LA, DeCresce RP, García LF, Jaramillo A. Induction of transplantation tolerance by allogeneic donor-derived CD4+CD25+Foxp3+ regulatory T cells. ImmunoPharmacology. Varadero Beach, Cuba, 2008 65. Patel KP, Liptay MJ, Faber LP, Kim A, Jaramillo A, Coon JS, Bonomi P, Borgia JA. Molecular staging of NSCLC using tumor specific autoantibodies. Meeting of the American Association for Cancer Research. San Diego, California. 2008. 66. Mozes M, Harmon M, Jaramillo A, Labuda B. Correlations between responses to CDC guided screening questions for high risk behavior and results of EIA antibody screening assays in potential deceased organ donors. International Congress of the Transplantation Society. Sydney, Australia. 2008. 67. Harmon M, Mozes M, Jaramillo A, Labuda B. Correlation between CDC High Risk designation and positive viral screening tests: A retrospective analysis of 4,877 deceased organ donors. Meeting of the National Association of Transplant Coordinators. Boston, Massachusetts. 2008. 68. Jaramillo A, Labuda B, Turon J, Freedom D, Magas D. Single-antigen bead analysis: A highly accurate predictor of the outcome & strength of the flow cytometric crossmatch. Meeting of the American Society for Histocompatibility & Immunogenetics. San Francisco, California. 2009. 69. Lerret NM, Rogozinska M, Jaramillo A, Marzo AL. Mam-A2.4 DNA vaccination leads to generation of effector phenotype CD8+ T cells and results in tumor regression. Autumn Immunology Conference. Chicago, Illinois, 2009. 70. Jaramillo A, Labuda B, Turon J, Freedom D, Magas D. Luminex single antigen beads: A highly accurate tool to predict the outcome & strength of the flow cytometry crossmatch (virtual crossmatch). European Immunogenetics & Histocompatibility Conference, Florence, Italy, 2010. 71. Du Z, Weidner J, Ramahi S, Aggarwal N, Jaramillo A, Thistlethwaite JR, Josephson M, Marino SR. HLA antibody detected by solid-phase assay combined with flow cytometric crossmatch but not a single test predict long-term kidney graft survival. European Immunogenetics & Histocompatibility Conference, Florence, Italy, 2010. 72. Lerret NM, Rogozinska M, Jaramillo A, Marzo AL. Mam-A2.4 DNA vaccination leads to generation of effector phenotype CD8+ T cells and results in tumor regression. Rush University Forum for Research & Clinical Investigation. Chicago, Illinois. 2010.
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AndrĂŠs Jaramillo, Ph.D., HCLD/CC(ABB) 73. Lerret NM, Rogozinska M, Jaramillo A, Marzo AL. Mam-A2.4 DNA vaccination leads to the generation of effector phenotype CD8+ T cells when used in combination with lowdose TBI results in long-term tumor regression. International Congress of Immunology. Kobe, Japan. 2010. 74. Lerret NM, Rogozinska M, Jaramillo A, Marzo AL. Low-dose irradiation reduces lipid uptake in tumor resident dendritic cells which in combination with tumor specific CD8+ T cells induces regression and prevents relapse. Meeting of the American Association of Immunologists. Baltimore, Maryland. 2010. 75. Kanangat S, Prod M, Kurbegovic-Skaljic I, Jaramillo A. Painful family memories. Meeting of the American Society for Histocompatibility & Immunogenetics. Hollywood, Florida. 2010. 76. Jendrisak MD, Kalra S, Harmon M, Skolek R, Jaramillo A, Schwartz, M, Cimbulak D. Use of a donor kidney biopsy audit score to clarify histopathology findings impacting organ utilization for transplantation. American Transplant Congress. Philadelphia, Pennsylvania. 2011. 77. Lerret NM, Rogozinska M, Jaramillo A, Marzo AL. Low-dose irradiation reduces lipid uptake in tumor resident dendritic cells which in combination with tumor specific CD8+ T cells induces regression and prevents relapse. Meeting of the American Association of Immunologists. San Franscisco, California. 2011. 78. Jaramillo A, Labuda B, Turon J, Freedom D, Magas D, Jendrisak MD, Jennings LJ, Kanangat S, Lower F, Susskind B, Marino SR, Gaitonde S, Tambur AR. Significant increase of kidney transplants in highly sensitized patients by implementation of the virtual crossmatch. Meeting of the American Society for Histocompatibility & Immunogenetics. New Orleans, Louisiana. 2011. 79. Du Z, Labuda B, Jaramillo A, Gaitonde S. Monitoring donor-specific antibody strength by Luminex single antigen bead assay aids kidney post-transplant clinical management: Two case reports. Meeting of the American Society for Histocompatibility & Immunogenetics. New Orleans, Louisiana. 2011. 80. Kanangat S, Prod MH, Oppermann M, Piggott SC, Kurbegovic-Skaljic I, Jensik S, Jaramillo A. Is a 10/10 really perfect? Meeting of the American Society for Histocompatibility & Immunogenetics. New Orleans, Louisiana. 2011. 81. Jaramillo A, Jendrisak MD, Labuda B, Jennings LJ, Kanangat S, Lower F, Susskind B, Marino SR, Gaitonde S, Tambur AR. Significant increase of deceased donor kidney transplant rates in sensitized patients with the use of the virtual crossmatch. American Transplant Congress. Boston, Massachusetts. 2012. 82. Jendrisak MD, Jendrisak A, Harmon M, Jaramillo A, Cimbulak D. Utilization and outcomes of deceased donor kidneys evaluated by biopsy. American Transplant Congress. Boston, Massachusetts. 2012. 83. Jendrisak MD, Harmon M, Jendrisak A, Jaramillo A. A priority approach to donation after cardiac death (DCD). American Transplant Congress, Boston, Massachusetts. 2012. 84. Theodoropoulos N, Wasik C, Brooks K, Ison MG, Jendrisak MD, Jaramillo A. Comparison of syphilis screening tests in deceased organ donors. American Transplant Congress. Boston, Massachusetts. 2012. 85. Theodoropoulos N, Nowicki M, Chinchilla-Reyes C, Pancoska C, Jaramillo A, Mone T, Hasz R, Jendrisak MD, Ladner DP, Ison MG. Discordant serology and nucleic acid testing results for HIV, HBV and HCV in 2010. American Transplant Congress. Boston, Massachusetts. 2012.
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) 86. Theodoropoulos N, Eidbo E, Paster M, Jaramillo A, Ladner DP, Ison MG. Screening Deceased Organ Donors for HIV, HBV and HCV: A Survey of Organ Procurement Organizations Practices. American Transplant Congress. Boston, Massachusetts. 2012. 87. Theodoropoulos N, Wasik C, Brooks K, Ladner DP, Jendrisak MD, Jaramillo A, Ison MG. Comparison of syphilis screening tests in deceased organ donors. International Congress of the Transplantation Society. Berlin, Germany. 2012. 88. Theodoropoulos N, Eidbo E, Paster M, Jaramillo A, Ladner DP, Ison MG. Screening Deceased organ donors for syphilis: A survey of OPO practices. International Congress of the Transplantation Society. Berlin, Germany. 2012. 89. Mehendale S, Labuda B, Jaramillo A, Gaitonde S. Significant increase in cadaveric renal transplants in highly sensitized patients by implementation of the virtual crossmatch: A unicenter experience. Meeting of the United States & Canadian Academy of Pathology. Vancouver, Canada. 2012. 90. Singh M, Setty S, Jaramillo A, Gaitonde S. Strength of donor specific antibodies detected by Luminex single antigen bead assay correlates with C4d positivity in kidney transplant biopsies and guides clinical management to prevent allograft loss. Meeting of the Academy of Clinical Laboratory Physicians and Scientists. Milwaukee, Wisconsin, 2012. 91. Theodoropoulos N, Jaramillo A, Wasik C, Brooks K, Ladner DP, Jendrisak MD, Ison MG. Comparison of syphilis screening tests in deceased organ donors. Meeting of the Association of Organ Procurement Organizations. Chicago, Illinois. 2012. 92. Du Z, Mehendale S, Labuda B, Jaramillo A, Gaitonde S. Significant increase in deceased donor kidney transplants in highly sensitized patients by implementation of the virtual crossmatch: A unicenter experience. Meeting of the American Society for Histocompatibility & Immunogenetics. San Juan, Puerto Rico. 2012. 93. Du Z, Kowalkowski N, Sun W, Kristin Dastych K, Jaramillo A, Gaitonde S. HLA antibody against self and donor HLA-C*04:01 molecule: DSA or not? Meeting of the American Society for Histocompatibility & Immunogenetics. San Juan, Puerto Rico. 2012. 94. Sieg K, Magas D, Brooks K, Carrera JD, Labuda B, Jendrisak MD, Jaramillo A. FalsePositive T-Cell Flow Cytometry Crossmatch Results With Pronase-Treated Cells in HIVPositive Patients. Meeting of the American Society for Histocompatibility & Immunogenetics. San Juan, Puerto Rico. 2012. GRANT SUPPORT
Research Grant Jaramillo (PI) 07/2007 - 07/2009 Prevent Cancer Foundation $40,000 “Characterization of T cell immune responses to mammaglobin-A” Role: PI Research Grant Jaramillo (PI) 05/2007 - 04/2009 The Brian Piccolo Cancer Research Foundation $50,000 “Definition of tumor-associated antibodies: Towards the diagnosis of non-small cell lung cancer” Role: PI Research Grant Jaramillo (PI) 05/2006 - 04/2009 The Susan G. Komen Breast Cancer Foundation $65,000 “Characterization of CD4+ and CD8+ T cell immune responses to mammaglobin-A” Role: PI Biomedical Research Grant Jaramillo (PI) 07/2005 - 12/2007 Page 17 of 19
Andrés Jaramillo, Ph.D., HCLD/CC(ABB)
American Lung Association $40,000 “Role of MMP-9 in experimental bronchiolitis obliterans” Role: PI 1-RO1-HL056643 Mohanakumar (PI) 08/2004 - 07/2008 NIH/SAT/NHLB $250,000 “Immune mechanisms of rejection in human lung allografts” Role: Co-investigator 1-RO1-DK065982 Mohanakumar (PI) 08/2004 - 07/2009 NIH/NIDDK $250,000 “Immune response to hepatitis C in liver transplantation” Role: Co-investigator 2-RO1-HL66452 Mohanakumar (PI) 12/2004 - 11/2008 NIH/SAT/NHLBI $250,000 “Pathogenesis of post-transplant bronchiolitis obliterans” Role: Co-investigator Research Grant Mohanakumar (PI) 05/2003 - 04/2005 Susan G. Komen Breast Cancer Foundation $62,000 “Definition of the T cell-mediated immune response to mammaglobin-A: A novel breast cancer-associated protein” Role: Co-investigator Research Grant Mohanakumar (PI) 07/2003 - 06/2005 American Liver Foundation $50,000 “Immune response to hepatitis C viral infection in liver transplant recipients” Role: Co-investigator Grant-in-Aid Jaramillo (PI) 07/2003 - 06/2006 American Heart Association $55,000 “Definition of the role of MMP-2 in the pathogenesis of cardiac allograft rejection” Role: PI Basic Scientist Faculty Grant Jaramillo (PI) 07/2001 - 06/2003 American Society of Transplantation $40,000 “The role of MMPs in the pathogenesis of post-transplant obliterative airway disease” Role: PI 2-RO1-NS33406 Mackinnon (PI) 08/2001 - 07/2006 NIH/SAT/NHLBI $250,000 “Nerve allotransplantation for traumatic nerve injury” Role: Co-investigator 1-RO1-HL66452 Mohanakumar (PI) 12/2000 - 11/2004 NIH/SAT/NHLBI $225,000 “Pathogenesis of post-transplant bronchiolitis obliterans” Role: Co-investigator
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Andrés Jaramillo, Ph.D., HCLD/CC(ABB) MENTORING & TRAINING Ph.D. Students:
Margarita M. Velásquez-Lopera, M.D. Graduate Program in Basic Biomedical Sciences University of Antioquia Medellín, Colombia Nadine M. Lerret Department of Immunology & Microbiology Rush University Chicago, Illinois
2004 - 2008
2006 - 2011
M.S. Students:
José Robinson Ramírez-Pineda Department of Biology University of Antioquia Medellín, Colombia Syeda Razvi Department of Clinical Laboratory Science Rush University Chicago, Illinois Valerie L. Eaton Department of Immunology & Microbiology Rush University Chicago, Illinois Navin Albazi Department of Clinical Laboratory Science Rush University Chicago, Illinois
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1995 - 1997
2005
2005 - 2007
2008