Sciencedirect com neuropeptides effect of methionine enkephalin plus zncl2 on active t cell rosettes

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Volume 5, Issues 4–6, February 1985, Pages 367–370 Proceedings of the International Narcotic Research Conference

This article belongs to a special issue PPrroocceeeeddiinnggss ooff tthhee IInntteerrnnaattiioonnaall N Naarrccoottiicc R Reesseeaarrcchh C Coonnffeerreennccee

E Effffeecctt ooff m meetthhiioonniinnee--eennkkeepphhaalliinn pplluuss ZZnnC Cll2 oonn aaccttiivvee TT cceellll rroosseetttteess Anthony J. Murgo Department of Medicine, West Virginia University Medical Center Morgantown, WV 26506 USA

Nicholas P. Plotnikoff Department of Pharmacology Oral Roberts University School of Medicine Tulsa, OK USA

Robert E. Faith

Other articles from this special issue EEffffeecctt ooff W Wiinn 4444444411--33 aanndd nnaallooxxoonnee oonn … … A.F. DeFelice , J.D. Norton , H.E. Lape , W.F. Mic… Show more information

TThhee eeffffeeccttss ooff sseelleeccttiivvee ooppiiooiidd ddeellttaa--rreecc… … S.L. Hart , Helen Slusarczyk , T.W. Smith Show more information

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Department of Biology University of Houston Houston, TX USA http://dx.doi.org/10.1016/0143-4179(85)90030-7, How to Cite or Link Using DOI Permissions & Reprints

D.S. Baskin , H. Kuroda , Y. Hosobuchi , N.M. Lee Show more information

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Abstract Methionine-enkephalin (Met-Enk) and ZnCl2 in combination enhances active T cell rosette formation of human peripheral blood lymphocytes to a greater degree than either of the agents used separately. Enhancement of rosette formation by Met-Enk plus ZnCl2 was not inhibited by the opiate receptor

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antagonist naloxone but was completely blocked by the zinc chelator 1, 10-phenathroline. The results suggest a relationship between zinc and Met-Enk and that zinc may be a modulator of enkephalin binding and function in the immune system as well as the nervous system.

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G.C. Miller, A.J. Murgo, N.P. Plotnikoff EEnnkkeepphhaalliinnss:: eennhhaanncceem meenntt ooff aaccttiivvee TT--cceellll rroosseetttteess ffrroom m nnoorrm maall vvoolluunntteeeerrss Clin. Immunol. Immunopathol., 31 (1984), pp. 132–137

Article | 2.

PDF (376 K) | View Record in Scopus | Cited By in Scopus (9)

J. Wybran, T. Appelboom, J-P. Famaey, A. Govaerts SSuuggggeessttiivvee eevviiddeennccee ffoorr rreecceeppttoorrss ffoorr m moorrpphhiinnee aanndd m meetthhiioonniinnee--eennkkeepphhaalliinn oonn nnoorrm maall hhuum maann bblloooodd TT llyym mpphhooccyytteess J. Immunol., 123 (1979), pp. 1068–1070

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N.P. Plotnikoff, G.C. Miller, A.J. Murgo EEnnkkeepphhaalliinnss:: SSttrreessss aanndd IIm mm muunniittyy E.L. Cooper (Ed.), Stress, Immunity, and Aging, Marcel Dekker, Inc, New York (1984), pp. 249–255

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K. Stengaard-Pedersen IInnhhiibbiittiioonn ooff eennkkeepphhaalliinn bbiinnddiinngg ttoo ooppiiaattee rreecceeppttoorrss bbyy zziinncc iioonnss:: ppoossssiibbllee pphhyyssiioollooggiiccaall iim mppoorrttaannccee iinn tthhee bbrraaiinn Acta pharmacol. et toxicol., 50 (1982), pp. 213–220

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R.O. Williams, L.A. Loeb ZZiinncc rreeqquuiirreem meenntt ffoorr D DN NAA rreepplliiccaattiioonn iinn ssttiim muullaatteedd hhuum maann llyym mpphhooccyytteess J. Cell Biol., 58 (1973), pp. 594–601

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M. Dardenne, J.-M. Pleau, B. Nabarra et al. C Coonnttrriibbuuttiioonn ooff zziinncc aanndd ootthheerr m meettaallss ttoo tthhee bbiioollooggiiccaall aaccttiivviittyy ooff tthhee sseerruum m tthhyym miicc ffaaccttoorr Proc. Natl. Acad. Sci. U.S.A. (2nd edition), 79 (1982), pp. 5370–5373

View Record in Scopus | Full Text via CrossRef | Cited By in Scopus (123) reprint requests to A.J.M. Copyright © 1985 Published by Elsevier Ltd.

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